Beyond Tumors: Gastric Syphilis Emulating a Gastric Neoplasia
We present the case of a 35-year-old male with a first-degree family history of gastric cancer (his father was diagnosed at the age of 45), who was presumed to have gastric cancer himself when evaluating the features of his upper endoscopy performed after hematemesis. Surprisingly, no cancer cells were found in the biopsies. Thanks to a different diagnostic suspicion subsequent to performing a full clinical history, a more favorable diagnosis was reached: gastric syphilis.PMID:38674276 | PMC:PMC11052094 | DOI:10.3390/medicina60040629 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Claudia Guerrero Mu ñoz Andres Casta ñeda Agredo Maria Jose Romero Valle Andr és Mauricio Silva Silva Marta Le ón Del Campo Claudia Azpirtarte S ánchez Marta Dom ínguez Fraga Manuel Vicente Mil án Pilo Benjamin Arturo Polo Lorduy Agustina Gonz ále Source Type: research

Systematic Review and Meta-Analysis on Optimal Timing of Surgery for Acute Symptomatic Metastatic Spinal Cord Compression
Conclusion: Our study highlights that a 48 h window may be the safest and most beneficial for patients presenting with acute MSCC and a life expectancy of over three months.PMID:38674277 | PMC:PMC11052148 | DOI:10.3390/medicina60040631 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Nicola Bresolin Luca Sartori Giacomo Drago Giulia Pastorello Paolo Gallinaro Jacopo Del Verme Roberto Zanata Enrico Giordan Source Type: research

Assessing the Feasibility and Efficacy of Pre-Sleep Dim Light Therapy for Adults with Insomnia: A Pilot Study
Conclusions: This study provides evidence for the efficacy of LT in improving sleep quality and circadian rhythm alignment in adults with insomnia. Despite limitations, such as a small sample size and short study duration, the results underscore the potential of LT as a viable non-pharmacological approach for insomnia. Future research should expand on these results with larger and more diverse cohorts followed over a longer period to validate and further elucidate the value of LT in sleep medicine. Trial registration: The trial was registered with the Clinical Research Information Service (KCT0008501).PMID:38674278 | PMC:P...
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Jihyun Yoon Seok-Jae Heo Hyangkyu Lee Eun-Gyeong Sul Taehwa Han Yu-Jin Kwon Source Type: research

Endoscopic Gallbladder Drainage: A Comprehensive Review on Indications, Techniques, and Future Perspectives
Medicina (Kaunas). 2024 Apr 14;60(4):633. doi: 10.3390/medicina60040633.ABSTRACTIn recent years, therapeutic endoscopy has become a fundamental tool in the management of gallbladder diseases in light of its minimal invasiveness, high clinical efficacy, and good safety profile. Both endoscopic transpapillary gallbladder drainage (TGBD) and endoscopic ultrasound (EUS)-guided gallbladder drainage (EUS-GBD) provide effective internal drainage in patients with acute cholecystitis unfit for cholecystectomy, avoiding the drawbacks of external percutaneous gallbladder drainage (PGBD). The availability of dedicated lumen-apposing m...
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Edoardo Troncone Rosa Amendola Alessandro Moscardelli Elena De Cristofaro Pasquale De Vico Omero Alessandro Paoluzi Giovanni Monteleone Manuel Perez-Miranda Giovanna Del Vecchio Blanco Source Type: research

Treatment Nonadherence among Multimorbid Chronic Disease Patients: Evidence from 3515 Subjects in Indonesia
Conclusions: While the prevalence of multimorbidity in Indonesia is generally similar to that observed in previous studies, we have identified patient characteristics related to nonadherence. We suggest that patient's nonadherence was primarily dictated by their self-perception of health and treatment complexity. With the longstanding issue of nonadherence, this study indicated the need to consider creating patient-tailored treatment programs in clinical practice to improve adherence by considering individual patients' characteristics.PMID:38674280 | PMC:PMC11052292 | DOI:10.3390/medicina60040634 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Ivan Surya Pradipta Kevin Aprilio Yozi Fiedya Ningsih Mochammad Andhika Aji Pratama Sofa Dewi Alfian Rizky Abdulah Source Type: research

Beyond Weight Loss: A Comprehensive Review of Pregnancy Management following Bariatric Procedures
Medicina (Kaunas). 2024 Apr 15;60(4):635. doi: 10.3390/medicina60040635.ABSTRACTThe increasing prevalence of bariatric surgery among women of childbearing age raises critical questions about the correct management of pregnancy following these procedures. This literature review delves into the multifaceted considerations surrounding pregnancy after bariatric surgery, with a particular focus on the importance of preconception counselling, appropriate nutrition assessment, and the necessity of correct folic acid supplementation. Key areas of investigation include nutrient absorption challenges, weight gain during pregnancy, a...
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Iulia Hulu ță Livia-Mihaela Apostol Radu Botezatu Anca Maria Panaitescu Corina Gic ă Romina-Marina Sima Nicolae Gic ă Florina Mihaela Nedelea Source Type: research

Time Course of Asymptomatic Stenosis in Multiple Lumbar Spinal Stenosis-Five-Year Results of Selective Decompression of Symptomatic Levels
Conclusion: Patients with asymptomatic L3-4 stenosis on preoperative MRI were not prone to develop new symptoms or need additional L3-4-level surgery within 5 years after surgery when compared to patients without preoperative L3-4 stenosis. These results indicate that prophylactic decompression for asymptomatic levels is unnecessary.PMID:38674282 | PMC:PMC11052377 | DOI:10.3390/medicina60040636 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Kazuyuki Watanabe Koji Otani Takuya Nikaido Kinshi Kato Hiroshi Kobayashi Shoji Yabuki Shin-Ichi Konno Yoshihiro Matsumoto Source Type: research

Association between Genetic Polymorphism of < em > SCN1A < /em > , < em > GABRA1 < /em > and < em > ABCB1 < /em > and Drug Responsiveness in Vietnamese Epileptic Children
Conclusions: Our study demonstrated a significant association between the SCN1A genetic polymorphism which increased risk of drug-resistant epilepsy in Vietnamese epileptic children. This important finding further supports the underlying molecular mechanisms of SCN1A genetic variants in the pathogenesis of drug-resistant epilepsy in children.PMID:38674283 | DOI:10.3390/medicina60040637 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Hai Xuan Tang Muoi Dang Ho Nhung Phuong Vu Hung Vu Cao Vinh Anh Ngo Van Thi Nguyen Thuan Duc Nguyen Ton Dang Nguyen Source Type: research

Management of Malignant Gastric Outlet Obstruction: A Comprehensive Review on the Old, the Classic and the Innovative Approaches
Medicina (Kaunas). 2024 Apr 16;60(4):638. doi: 10.3390/medicina60040638.ABSTRACTGastrojejunostomy is the principal method of palliation for unresectable malignant gastric outlet obstructions (GOO). Gastrojejunostomy was traditionally performed as a surgical procedure with an open approach butrecently, notable progress in the development of minimally invasive procedures such as laparoscopic gastrojejunostomies have emerged. Additionally, advancements in endoscopic techniques, including endoscopic stenting (ES) and endoscopic ultrasound-guided gastroenterostomy (EUS-GE), are becoming more prominent. ES involves the placement...
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Alessandro Fugazza Marta Andreozzi Hamid Asadzadeh Aghdaei Agustin Insausti Marco Spadaccini Matteo Colombo Silvia Carrara Maria Terrin Alessandro De Marco Gianluca Franchellucci Kareem Khalaf Pardis Ketabi Moghadam Chiara Ferrari Andrea Anderloni Giovann Source Type: research

Olmutinib Reverses Thioacetamide-Induced Cell Cycle Gene Alterations in Mice Liver and Kidney Tissues, While Wheat Germ Treatment Exhibits Limited Efficacy at Gene Level
Conclusions: It was predicted that the increased expression of the MKi67 gene by TAA leads to the increase in TP53, which negatively regulates the cell cycle via increased CDKN3 expression in kidneys and the restoration of TP53 levels in the liver. These findings contribute to our understanding of the effects of olmutinib and WGO on TAA-induced gene expression changes and highlight their contrasting effects based on cell cycle alterations.PMID:38674285 | DOI:10.3390/medicina60040639 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Seema Zargar Tanveer A Wani Salman Alamery Fatimah Yaseen Source Type: research

Socioeconomic and Other Risk Factors for Retear after Arthroscopic Surgery for Nontraumatic Rotator Cuff Tear
Conclusions: Age, initial tear size, and symptom duration significantly affect retear risk after arthroscopic rotator cuff repair. Occupation and type of medical insurance were also risk factors for retear. Socioeconomically vulnerable patients may be at a greater risk of retear. Proactive efforts are required to expand early access to medical care.PMID:38674286 | PMC:PMC11052191 | DOI:10.3390/medicina60040640 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Jung Sub Lee Kuen Tak Suh Won Chul Shin Jung Yun Bae Tae Sik Goh Sung Won Jung Min-Hyeok Choi Suk-Woong Kang Source Type: research

O < sub > 2 < /sub > Saturation Predicted the ICU Stay of COVID-19 Patients in a Hospital at Altitude: A Low-Cost Tool for Post-Pandemic
Conclusions: PO2S is a crucial factor in estimating ICU stays for COVID-19 patients at high altitudes and serves as an accessible and cost-effective measure. It should be used in infected patients to complement the prognosis of post-pandemic ICU stay.PMID:38674287 | PMC:PMC11052252 | DOI:10.3390/medicina60040641 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Jaime V ásquez-Gómez Lucero Gutierrez-Gutierrez Pablo Miranda-Cuevas Luis R íos-Florez Luz Casas-Condori Marcia Gumiel Marcelo Castillo-Retamal Source Type: research

Relationship between Depressive Symptoms, Caregiver Strain, and Social Support with Dementia Grief in Family Caregivers
Conclusions: In family caregivers, depressive symptoms, caregiver strain, and social support are related to the intensity of dementia grief, with a greater influence of depressive symptoms. Moreover, being female, having a low level of education, and caring for a care recipient at an advanced stage of dementia are factors associated with increased dementia grief. Concerning study limitations, the sample was restricted, belonging to a specific region of Spain and to a Provincial Federation of associations. It is necessary to exercise caution in generalizing results due to the sociodemographic and geographical characteristic...
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Miriam S ánchez-Alcón Almudena Garrido-Fern ández Jos é María Cano-Rojas Jos é Luis Sánchez-Ramos Juan Diego Ramos-Pichardo Source Type: research

Acute Infectious Purpura Fulminans Complicated by Bacterial Translocation after Rectal Cancer Surgery: A Case Report
Medicina (Kaunas). 2024 Apr 17;60(4):644. doi: 10.3390/medicina60040644.ABSTRACTThe patient was a man in his 80s who had undergone laparoscopic anterior resection for rectal cancer. Bowel obstruction occurred on the third postoperative day but improved with a decompression tube by the fifth postoperative day. A high fever (in the 38 °C range) was also observed. Blood culture tests detected two sets of the gram-negative bacilli Klebsiella aerogenes within 24 h of collection. On the seventh postoperative day, the patient subsequently went into septic shock with disseminated intravascular coagulation (DIC). On the eighth pos...
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Ryo Nakanishi Heita Ozawa Naoyuki Toyota Minori Mise Ritsuto Akutsu Shin Fujita Source Type: research

Adherence to the Mediterranean Diet in Saudi Arabia and Its Association with Socioeconomic Status and Depression
Conclusions: MedDiet adherence was associated with lower depression severity scores. In addition to education and television ownership, adherence was not associated with any objective indicators of SES.PMID:38674290 | PMC:PMC11051785 | DOI:10.3390/medicina60040642 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Majed Alnabulsi Ahmad Abdullah Imam Atheer Ahmed Alawlaqi Fatimah Hussain Alhawaj Ghazal Fareed Jamjoom Lina Dakhil Alsaeidi Fatma El-Sayed Hassan Shakeel Ahmed Ansari Source Type: research