Facilitated lexical processing accuracy and reaction times following repetitive Transcranial Magnetic Stimulation in dementia of the Alzheimer type: a case study
Neurocase. 2024 May 3:1-9. doi: 10.1080/13554794.2024.2348222. Online ahead of print.ABSTRACTWe investigated the potential effects of high-frequency (10 Hz) repetitive Transcranial Magnetic Stimulation (rTMS) of the bilateral Dorsolateral Prefrontal Cortex (DLPFC) (30-sessions; 2-sessions/day) on improving lexical processing in one participant with mild - Alzheimer's disease (hereafter dementia of the Alzheimer type-DAT). Increased accuracy and faster reaction times (RTs) were reported in a lexical-decision task (LDT) up to 2-months post-intervention. The current findings indicate that high-frequency stimulation of the DLP...
Source: Neurocase - May 3, 2024 Category: Neurology Authors: Georgia Roumpea Jurij Bon Katarina Marjanovi č Zvezdan Pirto šek Christina Manouilidou Source Type: research

Functional neuroimaging and behavioral correlates of multisite tDCS as an add-on to language training in a person with post-stroke non-fluent aphasia: a year-long case study
Neurocase. 2024 May 3:1-10. doi: 10.1080/13554794.2024.2349327. Online ahead of print.ABSTRACTMary, who experienced non-fluent aphasia as a result of an ischemic stroke, received 10 years of personalized language training (LT), resulting in transient enhancements in speech and comprehension. To enhance these effects, multisite transcranial Direct Current Stimulation (tDCS) was added to her LT regimen for 15 sessions. Assessment using the Reliable Change Index showed that this combination improved her left inferior frontal connectivity and speech production for two months and significantly improved comprehension after one m...
Source: Neurocase - May 3, 2024 Category: Neurology Authors: Augusto J Mendes Alberto Lema Jos é Miguel Soares Adriana Sampaio Jorge Leite Sandra Carvalho Source Type: research

Isolated bilateral fornix anterior columns infarction with acute amnesia and fiber tracts damage, a case report
We report the case of a 75-year-old female who experienced acute anterograde amnesia. MRI performed within 24 h after amnesia onset showed an isolated infarction of the bilateral anterior columns of the fornix on diffusion-weighted imaging (DWI). Her symptoms persisted for up to 50 days, and diffusion tensor imaging (DTI) showed disruption of the fiber tracts of the fornix. when acute amnesia syndrome onset, fornix anterior column infarction should be considered, and optimized DWI and DTI methods are needed to study the fornix in vivo in future research.PMID:38700142 | DOI:10.1080/13554794.2024.2348762 (Source: Neurocase)
Source: Neurocase - May 3, 2024 Category: Neurology Authors: Wen-Ting Yang Fu-Qiang Tang Source Type: research

Alcohol-related posterior reversible encephalopathy syndrome: a case report of a patient managed with a benzodiazepine-sparing regimen for alcohol withdrawal
We report a case of posterior reversible encephalopathy syndrome (PRES) during treatment for alcohol withdrawal syndrome with gabapentin and clonidine. The patient developed severe hypertension, confusion and tremor, culminating in bilateral vision loss and a seizure. Imaging revealed posterior cerebral edema. Treatment with benzodiazepines, antihypertensives, and anti-seizure medications led to resolution. One year later, imaging showed resolution of the findings. We review the associated literature and propose the recognition of a PRES sub-entity, Alcohol-Related PRES (ARPRES), which can appear in the setting of alcohol ...
Source: Neurocase - May 3, 2024 Category: Neurology Authors: Rafail A Chionatos David P Lerner Joseph D Burns Anil Ramineni Source Type: research

A case of Pitt-Hopkins syndrome: psychopharmacological approach for anxiety, insomnia, and agitation
We present the case report of a seven-year-old PTHS patient with anxiety, insomnia, and agitation. We discuss the psychopharmacological intervention options for this patient. The present case study reports on a 7-year-old female with PTHS, autism spectrum disorder (ASD), and intellectual disability. She had insomnia, crying spells and agitation complaints. For anxiety symptoms and agitation, risperidone, fluoxetine, and clonazepam treatment were given by the neurologist which caused behavioral disinhibition, paroxysmal agitation and no benefit. After admission to our hospital, aripiprazole and hydroxyzine were prescribed f...
Source: Neurocase - May 3, 2024 Category: Neurology Authors: Cemre Istanbullu Binay Kayan Ocakoglu Gul Karacetin Source Type: research

Lissencephaly: presentation of a clinical case of LIS 1 with a diagnosis confirmed by MLPA method and indications for rehabilitation treatment in childhood
Neurocase. 2024 May 3:1-10. doi: 10.1080/13554794.2024.2346985. Online ahead of print.ABSTRACTLissencephaly is a very rare clinical condition that affects the formation of the brain and causes severe psychomotor retardation, convulsions and muscular spasticity or hypotonia, often also associated with respiratory problems, facial dysmorphisms, abnormalities of the fingers and toes and difficulty swallowing resulting in reduced life expectancy. The clinical case described in the following article demonstrates the diagnostic process and rehabilitation treatment of a patient through a narrative review of the scientific literat...
Source: Neurocase - May 3, 2024 Category: Neurology Authors: Rita Abrunzo Source Type: research

When prion disease Isn't suspected: prion disease as the cause of terminal decline in chronic mixed dementia
Neurocase. 2024 Apr 30:1-6. doi: 10.1080/13554794.2024.2346990. Online ahead of print.ABSTRACTAlzheimer's Disease (AD) is the most common cause of dementia, although multiple pathologies are found in nearly half of the cases with clinically diagnosed AD. Prion diseases, such as Creutzfeldt-Jakob disease (CJD), are rare causes of dementia and typically manifest as a rapidly progressive dementia, where symptom onset to dementia most often occurs over the course of months. In this brief report, we describe a patient's typically progressive dementia with a precipitous decline at the end of their life who, on neuropathological ...
Source: Neurocase - April 30, 2024 Category: Neurology Authors: Sudarshan Krishnamurthy William Harrison Suzanne Craft Samuel N Lockhart James R Bateman Source Type: research

Cortical blindness after percutaneous vertebroplasty: a case report and comprehensive review of the literature
CONCLUSIONS: Percutaneous vertebroplasty, though helpful, carries a rare risk of cortical blindness. Surgeon awareness is crucial for informing patients of this potential complication.PMID:38687124 | DOI:10.1080/13554794.2024.2346984 (Source: Neurocase)
Source: Neurocase - April 30, 2024 Category: Neurology Authors: Chunnan Shi Zhijie Wang Meiying Lin Zhiqin Chen Peiyang Xu Yi Li Jinshan Zhang Source Type: research

When prion disease Isn't suspected: prion disease as the cause of terminal decline in chronic mixed dementia
Neurocase. 2024 Apr 30:1-6. doi: 10.1080/13554794.2024.2346990. Online ahead of print.ABSTRACTAlzheimer's Disease (AD) is the most common cause of dementia, although multiple pathologies are found in nearly half of the cases with clinically diagnosed AD. Prion diseases, such as Creutzfeldt-Jakob disease (CJD), are rare causes of dementia and typically manifest as a rapidly progressive dementia, where symptom onset to dementia most often occurs over the course of months. In this brief report, we describe a patient's typically progressive dementia with a precipitous decline at the end of their life who, on neuropathological ...
Source: Neurocase - April 30, 2024 Category: Neurology Authors: Sudarshan Krishnamurthy William Harrison Suzanne Craft Samuel N Lockhart James R Bateman Source Type: research

Cortical blindness after percutaneous vertebroplasty: a case report and comprehensive review of the literature
CONCLUSIONS: Percutaneous vertebroplasty, though helpful, carries a rare risk of cortical blindness. Surgeon awareness is crucial for informing patients of this potential complication.PMID:38687124 | DOI:10.1080/13554794.2024.2346984 (Source: Neurocase)
Source: Neurocase - April 30, 2024 Category: Neurology Authors: Chunnan Shi Zhijie Wang Meiying Lin Zhiqin Chen Peiyang Xu Yi Li Jinshan Zhang Source Type: research

When prion disease Isn't suspected: prion disease as the cause of terminal decline in chronic mixed dementia
Neurocase. 2024 Apr 30:1-6. doi: 10.1080/13554794.2024.2346990. Online ahead of print.ABSTRACTAlzheimer's Disease (AD) is the most common cause of dementia, although multiple pathologies are found in nearly half of the cases with clinically diagnosed AD. Prion diseases, such as Creutzfeldt-Jakob disease (CJD), are rare causes of dementia and typically manifest as a rapidly progressive dementia, where symptom onset to dementia most often occurs over the course of months. In this brief report, we describe a patient's typically progressive dementia with a precipitous decline at the end of their life who, on neuropathological ...
Source: Neurocase - April 30, 2024 Category: Neurology Authors: Sudarshan Krishnamurthy William Harrison Suzanne Craft Samuel N Lockhart James R Bateman Source Type: research

Cortical blindness after percutaneous vertebroplasty: a case report and comprehensive review of the literature
CONCLUSIONS: Percutaneous vertebroplasty, though helpful, carries a rare risk of cortical blindness. Surgeon awareness is crucial for informing patients of this potential complication.PMID:38687124 | DOI:10.1080/13554794.2024.2346984 (Source: Neurocase)
Source: Neurocase - April 30, 2024 Category: Neurology Authors: Chunnan Shi Zhijie Wang Meiying Lin Zhiqin Chen Peiyang Xu Yi Li Jinshan Zhang Source Type: research

Dystextia and dystypia due to phonological errors after ischemic stroke: a case report in a Japanese patient
Neurocase. 2024 Apr 26:1-8. doi: 10.1080/13554794.2024.2345403. Online ahead of print.ABSTRACTA 69-year-old Japanese male presented with acute dystextia and dystypia, defined as texting and typing impairments, respectively. His text input speed decreased due to a phonologically incorrect kana flick input on his smartphone. Additionally, dystypia occurred due to phonemic paragraphia of Romaji. Brain MRI revealed a new left lenticulostriate infarction sparing the cerebral cortex. SPECT showed reduced cerebral blood flow in the left inferior precentral frontal gyrus as well as in the infarction area. It was concluded that his...
Source: Neurocase - April 27, 2024 Category: Neurology Authors: Hiroshi Adachi Jun Numata Katsuya Nishida Hiroshi Yamasaki Naonobu Futamura Source Type: research

Multisensory perceptual distortion including auditory distortions in Alice in Wonderland syndrome: a case report
Neurocase. 2024 Apr 27:1-4. doi: 10.1080/13554794.2024.2345402. Online ahead of print.ABSTRACTAlice in Wonderland syndrome (AIWS) is a rare perceptual disorder characterized mainly by perceptual distortions of visual objects and one's own body. While there are many case reports of visual and somatosensory distortions associated with AIWS, little is known about auditory distortion. Therefore, we present the case of a 22-year-old right-handed woman who described having auditory as well as visual and somatosensory distortion experiences and a family history of AIWS. The subject reported experiencing multisensory perceptual di...
Source: Neurocase - April 27, 2024 Category: Neurology Authors: Godai Saito Gen Takagi Source Type: research

Back from the sideline, but back to baseline? A pediatric case study examining neuropsychological functioning after sustaining multiple sport-related concussions
Neurocase. 2024 Apr 27:1-8. doi: 10.1080/13554794.2024.2343154. Online ahead of print.ABSTRACTMost individuals recover quickly from a concussion; however, youth who sustain multiple concussions may be at risk for long-term cognitive impairments. This case study examines the neuropsychological performance of a 13-year-old malewith five head injuries. After his first concussion during study participation (fourth injury overall), several improvements were observed, likely due to practice effects, yet after sustaining another concussion <2 years later,declines were observed in visuoconstruction, verbal memory, and intellect...
Source: Neurocase - April 27, 2024 Category: Neurology Authors: Ryan C Thompson Dylan Vaughn Rayna B Hirst Rachel Murley Daniel Baldini Source Type: research