Association of Air Pollution with Risk and Severity of Obstructive Sleep Apnea: A Systematic Review and Meta-Analysis
CONCLUSION: The findings suggest air pollutants, especially NO2, might play a role in worsening OSA risk and severity, but the evidence isn't definitive. This highlights the variability of different pollutants' effects and the necessity for more research. Understanding these links is vital for shaping public health policies and clinical approaches to address OSA amidst high air pollution.PMID:38636605 | DOI:10.1016/j.neuro.2024.04.005 (Source: Neurotoxicology)
Source: Neurotoxicology - April 18, 2024 Category: Neurology Authors: Tahani Alrahbeni Jeetendra Kumar Gupta Anas Alkhouri Ladi Alik Kumar Ahmed Mahal Khalid Al-Mugheed Prakasini Satapathy Neelima Kukreti Mahalaqua Nazli Khatib Shilpa Gaidhane Abhay M Gaidhane Sarvesh Rustagi Dibyalochan Mohanty Bijaya Kumar Padhi Source Type: research

Association of Air Pollution with Risk and Severity of Obstructive Sleep Apnea: A Systematic Review and Meta-Analysis
CONCLUSION: The findings suggest air pollutants, especially NO2, might play a role in worsening OSA risk and severity, but the evidence isn't definitive. This highlights the variability of different pollutants' effects and the necessity for more research. Understanding these links is vital for shaping public health policies and clinical approaches to address OSA amidst high air pollution.PMID:38636605 | DOI:10.1016/j.neuro.2024.04.005 (Source: Neurotoxicology)
Source: Neurotoxicology - April 18, 2024 Category: Neurology Authors: Tahani Alrahbeni Jeetendra Kumar Gupta Anas Alkhouri Ladi Alik Kumar Ahmed Mahal Khalid Al-Mugheed Prakasini Satapathy Neelima Kukreti Mahalaqua Nazli Khatib Shilpa Gaidhane Abhay M Gaidhane Sarvesh Rustagi Dibyalochan Mohanty Bijaya Kumar Padhi Source Type: research

Association of Air Pollution with Risk and Severity of Obstructive Sleep Apnea: A Systematic Review and Meta-Analysis
CONCLUSION: The findings suggest air pollutants, especially NO2, might play a role in worsening OSA risk and severity, but the evidence isn't definitive. This highlights the variability of different pollutants' effects and the necessity for more research. Understanding these links is vital for shaping public health policies and clinical approaches to address OSA amidst high air pollution.PMID:38636605 | DOI:10.1016/j.neuro.2024.04.005 (Source: Neurotoxicology)
Source: Neurotoxicology - April 18, 2024 Category: Neurology Authors: Tahani Alrahbeni Jeetendra Kumar Gupta Anas Alkhouri Ladi Alik Kumar Ahmed Mahal Khalid Al-Mugheed Prakasini Satapathy Neelima Kukreti Mahalaqua Nazli Khatib Shilpa Gaidhane Abhay M Gaidhane Sarvesh Rustagi Dibyalochan Mohanty Bijaya Kumar Padhi Source Type: research

Effects of acute insecticide exposure on neuronal activity in vitro in rat cortical cultures
Neurotoxicology. 2024 Apr 9;102:58-67. doi: 10.1016/j.neuro.2024.04.004. Online ahead of print.ABSTRACTExposure to pesticides, such as carbamates, organophosphates, organochlorines and pyrethroids, has been linked to various health problems, including neurotoxicity. Although most in vivo studies use only male rodents, some studies have shown in vivo sex-specific effects after acute exposure. Since in vivo studies are costly and require a large number of animals, in vitro assays that take sex-specific effects into account are urgently needed. We therefore assessed the acute effects of exposure to different carbamates (metho...
Source: Neurotoxicology - April 10, 2024 Category: Neurology Authors: Lennart V J van Melis Anneloes M Peerdeman Eva H W Huiberts Regina G D M van Kleef Aart de Groot Remco H S Westerink Source Type: research

NUFIP1-engineered exosomes derived from hUMSCs regulate apoptosis and neurological injury induced by propofol in newborn rats
CONCLUSIONS: NUFIP1-engineered exosomes from hUMSCs have the potential to regulate nerve cell apoptosis and mitigate neurological injury induced by propofol in neonatal rats. Targeting NUFIP1 may hold great significance in ameliorating propofol-induced nerve injury.PMID:38599287 | DOI:10.1016/j.neuro.2024.04.002 (Source: Neurotoxicology)
Source: Neurotoxicology - April 10, 2024 Category: Neurology Authors: Wen Sun Pengyue Zhao Shidong Hu Zhenting Zhao Boyan Liu Xingpeng Yang Jiaqi Yang Ze Fu Songyan Li Wenli Yu Source Type: research

Evaluation of sub-chronic toxicity of melamine via systematic or oral delivery in adult zebrafish based on behavioral endpoints
Neurotoxicology. 2024 Apr 9;102:68-80. doi: 10.1016/j.neuro.2024.04.003. Online ahead of print.ABSTRACTMelamine-tainted products have been found in the market and raised issues about food safety. Recent studies done in rodents and humans demonstrated the toxicities of melamine, especially in causing kidney damage and bladder stone formation. However, very few studies assessed its behavior toxicity in organisms, including fish. Therefore, in this study, the researchers aim to determine whether sub-chronic exposure to melamine via oral and systematic administration could induce behavioral abnormality in zebrafish. After 14 d...
Source: Neurotoxicology - April 10, 2024 Category: Neurology Authors: Hsiu-Chao Chen Wen-Wei Feng Gilbert Audira Kevin Adi Kurnia San-Ho Hung Agnes L Castillo Marri Jmelou M Roldan Chung-Der Hsiao Chih-Hsin Hung Source Type: research

Effects of acute insecticide exposure on neuronal activity in vitro in rat cortical cultures
Neurotoxicology. 2024 Apr 9;102:58-67. doi: 10.1016/j.neuro.2024.04.004. Online ahead of print.ABSTRACTExposure to pesticides, such as carbamates, organophosphates, organochlorines and pyrethroids, has been linked to various health problems, including neurotoxicity. Although most in vivo studies use only male rodents, some studies have shown in vivo sex-specific effects after acute exposure. Since in vivo studies are costly and require a large number of animals, in vitro assays that take sex-specific effects into account are urgently needed. We therefore assessed the acute effects of exposure to different carbamates (metho...
Source: Neurotoxicology - April 10, 2024 Category: Neurology Authors: Lennart V J van Melis Anneloes M Peerdeman Eva H W Huiberts Regina G D M van Kleef Aart de Groot Remco H S Westerink Source Type: research

NUFIP1-engineered exosomes derived from hUMSCs regulate apoptosis and neurological injury induced by propofol in newborn rats
CONCLUSIONS: NUFIP1-engineered exosomes from hUMSCs have the potential to regulate nerve cell apoptosis and mitigate neurological injury induced by propofol in neonatal rats. Targeting NUFIP1 may hold great significance in ameliorating propofol-induced nerve injury.PMID:38599287 | DOI:10.1016/j.neuro.2024.04.002 (Source: Neurotoxicology)
Source: Neurotoxicology - April 10, 2024 Category: Neurology Authors: Wen Sun Pengyue Zhao Shidong Hu Zhenting Zhao Boyan Liu Xingpeng Yang Jiaqi Yang Ze Fu Songyan Li Wenli Yu Source Type: research

Evaluation of sub-chronic toxicity of melamine via systematic or oral delivery in adult zebrafish based on behavioral endpoints
Neurotoxicology. 2024 Apr 9;102:68-80. doi: 10.1016/j.neuro.2024.04.003. Online ahead of print.ABSTRACTMelamine-tainted products have been found in the market and raised issues about food safety. Recent studies done in rodents and humans demonstrated the toxicities of melamine, especially in causing kidney damage and bladder stone formation. However, very few studies assessed its behavior toxicity in organisms, including fish. Therefore, in this study, the researchers aim to determine whether sub-chronic exposure to melamine via oral and systematic administration could induce behavioral abnormality in zebrafish. After 14 d...
Source: Neurotoxicology - April 10, 2024 Category: Neurology Authors: Hsiu-Chao Chen Wen-Wei Feng Gilbert Audira Kevin Adi Kurnia San-Ho Hung Agnes L Castillo Marri Jmelou M Roldan Chung-Der Hsiao Chih-Hsin Hung Source Type: research

Effects of acute insecticide exposure on neuronal activity in vitro in rat cortical cultures
Neurotoxicology. 2024 Apr 9;102:58-67. doi: 10.1016/j.neuro.2024.04.004. Online ahead of print.ABSTRACTExposure to pesticides, such as carbamates, organophosphates, organochlorines and pyrethroids, has been linked to various health problems, including neurotoxicity. Although most in vivo studies use only male rodents, some studies have shown in vivo sex-specific effects after acute exposure. Since in vivo studies are costly and require a large number of animals, in vitro assays that take sex-specific effects into account are urgently needed. We therefore assessed the acute effects of exposure to different carbamates (metho...
Source: Neurotoxicology - April 10, 2024 Category: Neurology Authors: Lennart V J van Melis Anneloes M Peerdeman Eva H W Huiberts Regina G D M van Kleef Aart de Groot Remco H S Westerink Source Type: research

NUFIP1-engineered exosomes derived from hUMSCs regulate apoptosis and neurological injury induced by propofol in newborn rats
CONCLUSIONS: NUFIP1-engineered exosomes from hUMSCs have the potential to regulate nerve cell apoptosis and mitigate neurological injury induced by propofol in neonatal rats. Targeting NUFIP1 may hold great significance in ameliorating propofol-induced nerve injury.PMID:38599287 | DOI:10.1016/j.neuro.2024.04.002 (Source: Neurotoxicology)
Source: Neurotoxicology - April 10, 2024 Category: Neurology Authors: Wen Sun Pengyue Zhao Shidong Hu Zhenting Zhao Boyan Liu Xingpeng Yang Jiaqi Yang Ze Fu Songyan Li Wenli Yu Source Type: research

Evaluation of sub-chronic toxicity of melamine via systematic or oral delivery in adult zebrafish based on behavioral endpoints
Neurotoxicology. 2024 Apr 9;102:68-80. doi: 10.1016/j.neuro.2024.04.003. Online ahead of print.ABSTRACTMelamine-tainted products have been found in the market and raised issues about food safety. Recent studies done in rodents and humans demonstrated the toxicities of melamine, especially in causing kidney damage and bladder stone formation. However, very few studies assessed its behavior toxicity in organisms, including fish. Therefore, in this study, the researchers aim to determine whether sub-chronic exposure to melamine via oral and systematic administration could induce behavioral abnormality in zebrafish. After 14 d...
Source: Neurotoxicology - April 10, 2024 Category: Neurology Authors: Hsiu-Chao Chen Wen-Wei Feng Gilbert Audira Kevin Adi Kurnia San-Ho Hung Agnes L Castillo Marri Jmelou M Roldan Chung-Der Hsiao Chih-Hsin Hung Source Type: research

Effects of acute insecticide exposure on neuronal activity in vitro in rat cortical cultures
Neurotoxicology. 2024 Apr 9;102:58-67. doi: 10.1016/j.neuro.2024.04.004. Online ahead of print.ABSTRACTExposure to pesticides, such as carbamates, organophosphates, organochlorines and pyrethroids, has been linked to various health problems, including neurotoxicity. Although most in vivo studies use only male rodents, some studies have shown in vivo sex-specific effects after acute exposure. Since in vivo studies are costly and require a large number of animals, in vitro assays that take sex-specific effects into account are urgently needed. We therefore assessed the acute effects of exposure to different carbamates (metho...
Source: Neurotoxicology - April 10, 2024 Category: Neurology Authors: Lennart V J van Melis Anneloes M Peerdeman Eva H W Huiberts Regina G D M van Kleef Aart de Groot Remco H S Westerink Source Type: research

NUFIP1-engineered exosomes derived from hUMSCs regulate apoptosis and neurological injury induced by propofol in newborn rats
CONCLUSIONS: NUFIP1-engineered exosomes from hUMSCs have the potential to regulate nerve cell apoptosis and mitigate neurological injury induced by propofol in neonatal rats. Targeting NUFIP1 may hold great significance in ameliorating propofol-induced nerve injury.PMID:38599287 | DOI:10.1016/j.neuro.2024.04.002 (Source: Neurotoxicology)
Source: Neurotoxicology - April 10, 2024 Category: Neurology Authors: Wen Sun Pengyue Zhao Shidong Hu Zhenting Zhao Boyan Liu Xingpeng Yang Jiaqi Yang Ze Fu Songyan Li Wenli Yu Source Type: research

Evaluation of sub-chronic toxicity of melamine via systematic or oral delivery in adult zebrafish based on behavioral endpoints
Neurotoxicology. 2024 Apr 9;102:68-80. doi: 10.1016/j.neuro.2024.04.003. Online ahead of print.ABSTRACTMelamine-tainted products have been found in the market and raised issues about food safety. Recent studies done in rodents and humans demonstrated the toxicities of melamine, especially in causing kidney damage and bladder stone formation. However, very few studies assessed its behavior toxicity in organisms, including fish. Therefore, in this study, the researchers aim to determine whether sub-chronic exposure to melamine via oral and systematic administration could induce behavioral abnormality in zebrafish. After 14 d...
Source: Neurotoxicology - April 10, 2024 Category: Neurology Authors: Hsiu-Chao Chen Wen-Wei Feng Gilbert Audira Kevin Adi Kurnia San-Ho Hung Agnes L Castillo Marri Jmelou M Roldan Chung-Der Hsiao Chih-Hsin Hung Source Type: research