Impact of HLA-B51 on Uveitis and Retinal Vasculitis: Data from the AIDA International Network Registries on Ocular Inflammatory Disorders
CONCLUSIONS: Patients with NIU testing positive for HLA-B51 exhibit an increased likelihood of RV throughout disease course, irrespective of a systemic diagnosis of BD. The rate of complications as well as VA are comparable between NIU cases unrelated to BD testing positive for HLA-B51 and uveitis associated with BD. Therefore, it is advisable to perform the HLA-B typing in patients with NIU or retinal vasculitis, even in the absence of typical BD features.PMID:38759215 | DOI:10.1080/09273948.2024.2346815 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 17, 2024 Category: Allergy & Immunology Authors: Jurgen Sota Silvana Guerriero Giuseppe Lopalco Abdurrahman Tufan Gaafar Ragab Ibrahim AlMaglouth Marcello Govoni Petros P Sfikakis Micol Frassi Antonio Vitale Riza Can Kardas Paola Triaggianese Maria Sole Chimenti Aos A Aboabat Matteo Piga Sara Monti Gian Source Type: research
Clinical Insights: Antimicrobial Therapy for Infectious Uveitis
Ocul Immunol Inflamm. 2024 May 17:1-21. doi: 10.1080/09273948.2024.2345848. Online ahead of print.ABSTRACTInfectious uveitis is a major global cause of vision impairment. Despite the eye's immune privilege, afforded by the blood-ocular barrier that restricts microbial entry, several pathogens such as bacteria, viruses, fungi, and parasites can still infiltrate and cause ocular infections and complications. Clinicians often encounter significant challenges in treating infectious uveitis due to limited or ineffective treatment options. Modern molecular techniques and imaging can aid in diagnosing and assessing intraocular in...
Source: Ocular Immunology and Inflammation - May 17, 2024 Category: Allergy & Immunology Authors: Evangeline Leong Carlos Cifuentes-Gonz ález Jeremy Hu Y W Ramar Perumal Samy Moncef Khairallah William Rojas-Carabali Ikhwanuliman Putera Alejandra de-la-Torre Rupesh Agrawal Source Type: research
Treatment Outcomes of Intravitreal Aflibercept for Uveitic Macular Edema
CONCLUSION: Intravitreal aflibercept injections resulted in reduced central subfield thickness at all time-points. It appears to be an effective treatment alternative for UME, particularly for patients who are not responsive to local corticosteroids or who have contraindications to corticosteroid treatment.PMID:38759221 | DOI:10.1080/09273948.2024.2344709 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 17, 2024 Category: Allergy & Immunology Authors: Enny Oyeniran Sanjeeb Bhandari Ali Amir Matias Soifer Sunil Bellur Susan Vitale H Nida Sen Shilpa Kodati Source Type: research
Clinical Course and Outcomes of Autoimmune Versus Non-Autoimmune Surgically Induced Scleral Necrosis: A Multicentric Comparative Study
CONCLUSIONS: Eyes with autoimmune SISN had a higher rate of cataract surgery, severe scleral inflammation, and ocular complications. Early SISN diagnosis and appropriate management, based on clinical features and pathogenic mechanisms, are critical to avoid sight-threatening complications.PMID:38759224 | DOI:10.1080/09273948.2024.2349914 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 17, 2024 Category: Allergy & Immunology Authors: Raul E Ruiz-Lozano Eugenia M Ramos-D ávila Maria F Colorado-Zavala Manuel E Quiroga-Garza Nadim S Azar Hazem M Mousa Victor L Perez Maite Sainz-de-la-Maza C Stephen Foster Alejandro Rodriguez-Garcia Source Type: research
Management of Acute Non-Infectious Anterior Uveitis in Adults - Practice Patterns Among Uveitis Specialists in North America
CONCLUSION: Our results show that topical corticosteroid, most frequently prednisolone acetate 1%, is the treatment of choice for patients with acute noninfectious anterior uveitis. Reported initial medication dosing and follow-up care approaches are highly variable, which suggests heterogeneity in practice patterns. Further research on the optimal initial dosing is needed.PMID:38749068 | DOI:10.1080/09273948.2024.2346819 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 15, 2024 Category: Allergy & Immunology Authors: Howard Zhang Crystal M Nicholson John H Kempen Gui-Shuang Ying Sapna S Gangaputra Source Type: research
Childhood-Onset Non-Infectious Uveitis in the "Biologic Era". Results From Spanish Multicenter Multidisciplinary Real-World Clinical Settings
CONCLUSION: Prognosis of childhood uveitis has improved in the "biologic era," particularly in JIAu. Early referral and DMARD therapy may reduce steroid use and improve outcomes, especially in PP and IDIu.PMID:38728578 | DOI:10.1080/09273948.2024.2336609 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 10, 2024 Category: Allergy & Immunology Authors: Pablo Mesa-Del-Castillo In és Yago Ugarte J M Bolar ín David Mart ínez Berta L ópez Montesinos Honorio Barranco Gonz ález Inmaculada Calvo Penad és Lucia Lacruz P érez Daniel Clemente Juan Carlos Robledillo Isabel Valls Ferr án Beatriz Bravo Manch Source Type: research
Intermediate Uveitis with Cystoid Macular Edema as Presentation of Retained Caterpillar Hair in the Vitreous Cavity
CONCLUSION: We highlight a rare and unusual presentation of ophthalmia nodosa and its successful management.PMID:38713820 | DOI:10.1080/09273948.2024.2345282 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 7, 2024 Category: Allergy & Immunology Authors: Nitin Kumar Menia Sabia Handa Ashish Markan Umang Thakur Aniruddha Agarwal Vishali Gupta Source Type: research
Unveiling Key Pathological Indicators for Disease Progression in Vogt Koyanagi Harada Disease and Sympathetic Ophthalmia Through Advanced Choroidal Volume Analysis
CONCLUSIONS: The volume analysis of OCT images facilitates a three-dimensional visualization of choroidal alterations, which may serve as a reflection of disease severity in VKHD and SO patients. Furthermore, noninvasive initial CVV or CV measurements may serve as potential biomarkers for predicting disease recurrence in VKHD and SO.PMID:38709183 | DOI:10.1080/09273948.2024.2337836 (Source: Ocular Immunology and Inflammation)
Source: Ocular Immunology and Inflammation - May 6, 2024 Category: Allergy & Immunology Authors: Akira Tanikawa Kazuichi Maruyama Shiyi Liu Zaixing Mao Zhenguo Wang Nobuhiko Shiraki Noriyasu Hashida Ryo Kawasaki Kinpui Chan Kohji Nishida Source Type: research
