[Corrigendum] miR ‑27a promotes proliferation, migration, and invasion of colorectal cancer by targeting FAM172A and acts as a diagnostic and prognostic biomarker
Oncol Rep. 2024 Jun;51(6):83. doi: 10.3892/or.2024.8742. Epub 2024 Apr 26.ABSTRACTFollowing the publication of this article, an interested reader drew to the authors' attention that the western blots in Fig. 4B on p. 3560 and Fig. 6B on p. 3562 shared remarkably similar data (including both the GAPDH and the FAM172A blots in Fig. 4B), such that these data were likely to have been derived from the same original source. Upon asking the authors to provide an explanation, the authors realized that these errors inadvertently arose during the process of assembling these figures. Due to a mislabelling of the files, representative...
Source: Oncology Reports - April 26, 2024 Category: Cancer & Oncology Authors: Wenjun Liu Kai Qian Xing Wei Haijun Deng Bei Zhao Qing Chen Jinqian Zhang Hao Liu Source Type: research

Involvement of lncRNAs in the regulation of aerobic glycolysis in hepatocellular carcinoma: Main functions, regulatory mechanisms and potential therapeutic implications (Review)
Oncol Rep. 2024 Jun;51(6):84. doi: 10.3892/or.2024.8743. Epub 2024 Apr 26.ABSTRACTEven under aerobic conditions, tumor cells can reprogram their metabolism to preferentially metabolize glucose into lactic acid. This abnormal metabolic pattern, known as the 'Warburg' effect or aerobic glycolysis, promotes cancer progression. Long non‑coding RNAs (lncRNAs) are RNAs that are >200 nucleotides in length and do not have protein‑coding capabilities. However, these RNAs play a key role in tumor development. There is increasing evidence to indicate that lncRNAs regulate glucose metabolism in tumor cells by affecting metaboli...
Source: Oncology Reports - April 26, 2024 Category: Cancer & Oncology Authors: Qiongqing Huang Zhengui Liang Qiqi Huang Xueyu Li Jingjing Xia Lining Huang Lin Bing Huang Chao Ou Source Type: research

[Retracted] Fangchinoline suppresses growth and metastasis of melanoma cells by inhibiting the phosphorylation of FAK
Oncol Rep. 2024 Jun;51(6):81. doi: 10.3892/or.2024.8740. Epub 2024 Apr 26.ABSTRACTFollowing the publication of this paper, it was drawn to the Editor's attention by a concerned reader that certain of the Transwell migration and invasion assay data shown in Fig. 3C and D on p. 67 were strikingly similar to data appearing in different form in another pair of articles written by different authors at different research institutes, one of which (subsequently retracted) had already been published elsewhere prior to the submission of this paper to Oncology Reports, with the other having been submitted for publication at around th...
Source: Oncology Reports - April 26, 2024 Category: Cancer & Oncology Authors: Jie Shi Bingyu Guo Qiang Hui Peng Chang Kai Tao Source Type: research

Overexpression of ZNF169 promotes the growth and proliferation of colorectal cancer cells via the upregulation of ANKZF1
Oncol Rep. 2024 Jun;51(6):82. doi: 10.3892/or.2024.8741. Epub 2024 Apr 26.ABSTRACTColorectal cancer (CRC) is one of the most common malignancies worldwide. The 5‑year survival rate of patients diagnosed with the early stages of the disease is markedly higher than that of patients in the advanced stages. Therefore, identifying novel biomarkers and drug targets for CRC is critical for clinical practice. Zinc finger protein 169 (ZNF169) is a crucial transcription factor, and its role in CRC remains to be explored. The present study aimed to investigate the clinical relevance, function and underlying mechanisms of ZNF169 in ...
Source: Oncology Reports - April 26, 2024 Category: Cancer & Oncology Authors: Jie Zhang Ye Wang Shiyang Hou Xiaoqian Chi Danyang Ding Mei Xue Mengqiao Zhang Jing Wang Junfang Shuai Haiying Sun Qiang Gao Chunbo Kang Source Type: research

Developing innovative strategies of tumor ‑infiltrating lymphocyte therapy for tumor treatment
Oncol Rep. 2024 Jun;51(6):85. doi: 10.3892/or.2024.8744. Epub 2024 Apr 26.ABSTRACTCancer is the main cause of global mortality, and thus far, effective therapeutic strategies for cancer treatment are in high demand. Adoptive transfer of tumor‑infiltrating lymphocytes (TILs) represents a promising avenue in immunotherapy for the management of malignancies. The clinical safety and efficacy of TIL‑based therapy have been established through numerous rigorous clinical trials. However, the efficacy of TIL infusion in inducing an anti‑tumor response is limited to a subset of clinical patients with cancer. Therefore, there ...
Source: Oncology Reports - April 26, 2024 Category: Cancer & Oncology Authors: Zhongjie Yu Jianhua Shi Yuan Fang Yi Zhao Aotian Xu Ning Li Source Type: research

[Corrigendum] miR ‑27a promotes proliferation, migration, and invasion of colorectal cancer by targeting FAM172A and acts as a diagnostic and prognostic biomarker
Oncol Rep. 2024 Jun;51(6):83. doi: 10.3892/or.2024.8742. Epub 2024 Apr 26.ABSTRACTFollowing the publication of this article, an interested reader drew to the authors' attention that the western blots in Fig. 4B on p. 3560 and Fig. 6B on p. 3562 shared remarkably similar data (including both the GAPDH and the FAM172A blots in Fig. 4B), such that these data were likely to have been derived from the same original source. Upon asking the authors to provide an explanation, the authors realized that these errors inadvertently arose during the process of assembling these figures. Due to a mislabelling of the files, representative...
Source: Oncology Reports - April 26, 2024 Category: Cancer & Oncology Authors: Wenjun Liu Kai Qian Xing Wei Haijun Deng Bei Zhao Qing Chen Jinqian Zhang Hao Liu Source Type: research

Involvement of lncRNAs in the regulation of aerobic glycolysis in hepatocellular carcinoma: Main functions, regulatory mechanisms and potential therapeutic implications (Review)
Oncol Rep. 2024 Jun;51(6):84. doi: 10.3892/or.2024.8743. Epub 2024 Apr 26.ABSTRACTEven under aerobic conditions, tumor cells can reprogram their metabolism to preferentially metabolize glucose into lactic acid. This abnormal metabolic pattern, known as the 'Warburg' effect or aerobic glycolysis, promotes cancer progression. Long non‑coding RNAs (lncRNAs) are RNAs that are >200 nucleotides in length and do not have protein‑coding capabilities. However, these RNAs play a key role in tumor development. There is increasing evidence to indicate that lncRNAs regulate glucose metabolism in tumor cells by affecting metaboli...
Source: Oncology Reports - April 26, 2024 Category: Cancer & Oncology Authors: Qiongqing Huang Zhengui Liang Qiqi Huang Xueyu Li Jingjing Xia Lining Huang Lin Bing Huang Chao Ou Source Type: research

[Retracted] Fangchinoline suppresses growth and metastasis of melanoma cells by inhibiting the phosphorylation of FAK
Oncol Rep. 2024 Jun;51(6):81. doi: 10.3892/or.2024.8740. Epub 2024 Apr 26.ABSTRACTFollowing the publication of this paper, it was drawn to the Editor's attention by a concerned reader that certain of the Transwell migration and invasion assay data shown in Fig. 3C and D on p. 67 were strikingly similar to data appearing in different form in another pair of articles written by different authors at different research institutes, one of which (subsequently retracted) had already been published elsewhere prior to the submission of this paper to Oncology Reports, with the other having been submitted for publication at around th...
Source: Oncology Reports - April 26, 2024 Category: Cancer & Oncology Authors: Jie Shi Bingyu Guo Qiang Hui Peng Chang Kai Tao Source Type: research

Overexpression of ZNF169 promotes the growth and proliferation of colorectal cancer cells via the upregulation of ANKZF1
Oncol Rep. 2024 Jun;51(6):82. doi: 10.3892/or.2024.8741. Epub 2024 Apr 26.ABSTRACTColorectal cancer (CRC) is one of the most common malignancies worldwide. The 5‑year survival rate of patients diagnosed with the early stages of the disease is markedly higher than that of patients in the advanced stages. Therefore, identifying novel biomarkers and drug targets for CRC is critical for clinical practice. Zinc finger protein 169 (ZNF169) is a crucial transcription factor, and its role in CRC remains to be explored. The present study aimed to investigate the clinical relevance, function and underlying mechanisms of ZNF169 in ...
Source: Oncology Reports - April 26, 2024 Category: Cancer & Oncology Authors: Jie Zhang Ye Wang Shiyang Hou Xiaoqian Chi Danyang Ding Mei Xue Mengqiao Zhang Jing Wang Junfang Shuai Haiying Sun Qiang Gao Chunbo Kang Source Type: research

Developing innovative strategies of tumor ‑infiltrating lymphocyte therapy for tumor treatment
Oncol Rep. 2024 Jun;51(6):85. doi: 10.3892/or.2024.8744. Epub 2024 Apr 26.ABSTRACTCancer is the main cause of global mortality, and thus far, effective therapeutic strategies for cancer treatment are in high demand. Adoptive transfer of tumor‑infiltrating lymphocytes (TILs) represents a promising avenue in immunotherapy for the management of malignancies. The clinical safety and efficacy of TIL‑based therapy have been established through numerous rigorous clinical trials. However, the efficacy of TIL infusion in inducing an anti‑tumor response is limited to a subset of clinical patients with cancer. Therefore, there ...
Source: Oncology Reports - April 26, 2024 Category: Cancer & Oncology Authors: Zhongjie Yu Jianhua Shi Yuan Fang Yi Zhao Aotian Xu Ning Li Source Type: research

[Corrigendum] miR ‑27a promotes proliferation, migration, and invasion of colorectal cancer by targeting FAM172A and acts as a diagnostic and prognostic biomarker
Oncol Rep. 2024 Jun;51(6):83. doi: 10.3892/or.2024.8742. Epub 2024 Apr 26.ABSTRACTFollowing the publication of this article, an interested reader drew to the authors' attention that the western blots in Fig. 4B on p. 3560 and Fig. 6B on p. 3562 shared remarkably similar data (including both the GAPDH and the FAM172A blots in Fig. 4B), such that these data were likely to have been derived from the same original source. Upon asking the authors to provide an explanation, the authors realized that these errors inadvertently arose during the process of assembling these figures. Due to a mislabelling of the files, representative...
Source: Oncology Reports - April 26, 2024 Category: Cancer & Oncology Authors: Wenjun Liu Kai Qian Xing Wei Haijun Deng Bei Zhao Qing Chen Jinqian Zhang Hao Liu Source Type: research

Involvement of lncRNAs in the regulation of aerobic glycolysis in hepatocellular carcinoma: Main functions, regulatory mechanisms and potential therapeutic implications (Review)
Oncol Rep. 2024 Jun;51(6):84. doi: 10.3892/or.2024.8743. Epub 2024 Apr 26.ABSTRACTEven under aerobic conditions, tumor cells can reprogram their metabolism to preferentially metabolize glucose into lactic acid. This abnormal metabolic pattern, known as the 'Warburg' effect or aerobic glycolysis, promotes cancer progression. Long non‑coding RNAs (lncRNAs) are RNAs that are >200 nucleotides in length and do not have protein‑coding capabilities. However, these RNAs play a key role in tumor development. There is increasing evidence to indicate that lncRNAs regulate glucose metabolism in tumor cells by affecting metaboli...
Source: Oncology Reports - April 26, 2024 Category: Cancer & Oncology Authors: Qiongqing Huang Zhengui Liang Qiqi Huang Xueyu Li Jingjing Xia Lining Huang Lin Bing Huang Chao Ou Source Type: research

[Retracted] Fangchinoline suppresses growth and metastasis of melanoma cells by inhibiting the phosphorylation of FAK
Oncol Rep. 2024 Jun;51(6):81. doi: 10.3892/or.2024.8740. Epub 2024 Apr 26.ABSTRACTFollowing the publication of this paper, it was drawn to the Editor's attention by a concerned reader that certain of the Transwell migration and invasion assay data shown in Fig. 3C and D on p. 67 were strikingly similar to data appearing in different form in another pair of articles written by different authors at different research institutes, one of which (subsequently retracted) had already been published elsewhere prior to the submission of this paper to Oncology Reports, with the other having been submitted for publication at around th...
Source: Oncology Reports - April 26, 2024 Category: Cancer & Oncology Authors: Jie Shi Bingyu Guo Qiang Hui Peng Chang Kai Tao Source Type: research

Overexpression of ZNF169 promotes the growth and proliferation of colorectal cancer cells via the upregulation of ANKZF1
Oncol Rep. 2024 Jun;51(6):82. doi: 10.3892/or.2024.8741. Epub 2024 Apr 26.ABSTRACTColorectal cancer (CRC) is one of the most common malignancies worldwide. The 5‑year survival rate of patients diagnosed with the early stages of the disease is markedly higher than that of patients in the advanced stages. Therefore, identifying novel biomarkers and drug targets for CRC is critical for clinical practice. Zinc finger protein 169 (ZNF169) is a crucial transcription factor, and its role in CRC remains to be explored. The present study aimed to investigate the clinical relevance, function and underlying mechanisms of ZNF169 in ...
Source: Oncology Reports - April 26, 2024 Category: Cancer & Oncology Authors: Jie Zhang Ye Wang Shiyang Hou Xiaoqian Chi Danyang Ding Mei Xue Mengqiao Zhang Jing Wang Junfang Shuai Haiying Sun Qiang Gao Chunbo Kang Source Type: research

Developing innovative strategies of tumor ‑infiltrating lymphocyte therapy for tumor treatment
Oncol Rep. 2024 Jun;51(6):85. doi: 10.3892/or.2024.8744. Epub 2024 Apr 26.ABSTRACTCancer is the main cause of global mortality, and thus far, effective therapeutic strategies for cancer treatment are in high demand. Adoptive transfer of tumor‑infiltrating lymphocytes (TILs) represents a promising avenue in immunotherapy for the management of malignancies. The clinical safety and efficacy of TIL‑based therapy have been established through numerous rigorous clinical trials. However, the efficacy of TIL infusion in inducing an anti‑tumor response is limited to a subset of clinical patients with cancer. Therefore, there ...
Source: Oncology Reports - April 26, 2024 Category: Cancer & Oncology Authors: Zhongjie Yu Jianhua Shi Yuan Fang Yi Zhao Aotian Xu Ning Li Source Type: research