Polystyrene nanoplastics with different functional groups and charges have different impacts on type 2 diabetes
Increasing attention is being paid to the environmental and health impacts of nanoplastics (NPs) pollution. Exposure to nanoplastics (NPs) with different charges and functional groups may have different advers... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - April 24, 2024 Category: Toxicology Authors: Yunyi Wang, Ke Xu, Xiao Gao, Zhaolan Wei, Qi Han, Shuxin Wang, Wanting Du and Mingqing Chen Tags: Research Source Type: research

Acute exposure to polystyrene nanoparticles promotes liver injury by inducing mitochondrial ROS-dependent necroptosis and augmenting macrophage-hepatocyte crosstalk
The global use of plastic materials has undergone rapid expansion, resulting in the substantial generation of degraded and synthetic microplastics and nanoplastics (MNPs), which have the potential to impose si... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - April 12, 2024 Category: Toxicology Authors: Junjie Fan, Li Liu, Yongling Lu, Qian Chen, Shijun Fan, Yongjun Yang, Yupeng Long and Xin Liu Tags: Research Source Type: research

The discovery of regional neurotoxicity-associated metabolic alterations induced by carbon quantum dots in brain of mice using a spatial metabolomics analysis
Recently, carbon quantum dots (CQDs) have been widely used in various fields, especially in the diagnosis and therapy of neurological disorders, due to their excellent prospects. However, the associated inevit... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - April 10, 2024 Category: Toxicology Authors: Min Chen, Siyuan Chen, Xinyu Wang, Zongjian Ye, Kehan Liu, Yijing Qian, Meng Tang and Tianshu Wu Tags: Research Source Type: research

Micro- and nanoplastics concepts for particle and fibre toxicologists
Micro- and nanoplastic particles (MNP) are omnipresent as either pollution or intentionally used in consumer products, released from packaging or even food. There is an exponential increase in the production o... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - April 2, 2024 Category: Toxicology Authors: Stephanie Wright, Flemming R. Cassee, Aaron Erdely and Matthew J. Campen Tags: Comment Source Type: research

Ferroptosis contributing to cardiomyocyte injury induced by silica nanoparticles via miR-125b-2-3p/HO-1 signaling
Amorphous silica nanoparticles (SiNPs) have been gradually proven to threaten cardiac health, but pathogenesis has not been fully elucidated. Ferroptosis is a newly defined form of programmed cell death that i... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - April 1, 2024 Category: Toxicology Authors: Xueyan Li, Hailin Xu, Xinying Zhao, Yan Li, Songqing Lv, Wei Zhou, Ji Wang, Zhiwei Sun, Yanbo Li and Caixia Guo Tags: Research Source Type: research

In vitro inflammation and toxicity assessment of pre- and post-incinerated organomodified nanoclays to macrophages using high-throughput screening approaches
Organomodified nanoclays (ONC), two-dimensional montmorillonite with organic coatings, are increasingly used to improve nanocomposite properties. However, little is known about pulmonary health risks along the... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - March 21, 2024 Category: Toxicology Authors: Todd A. Stueckle, Jake Jensen, Jayme P. Coyle, Raymond Derk, Alixandra Wagner, Cerasela Zoica Dinu, Tiffany G. Kornberg, Sherri A. Friend, Alan Dozier, Sushant Agarwal, Rakesh K. Gupta and Liying W. Rojanasakul Tags: Research Source Type: research

Epithelial MAPK signaling directs endothelial NRF2 signaling and IL-8 secretion in a tri-culture model of the alveolar-microvascular interface following diesel exhaust particulate (DEP) exposure
Particulate matter 2.5 (PM2.5) deposition in the lung ’s alveolar capillary region (ACR) is significantly associated with respiratory disease development, yet the molecular mechanisms are not completely understood... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - March 11, 2024 Category: Toxicology Authors: Eva C. M. Vitucci, Alysha E. Simmons, Elizabeth M. Martin and Shaun D. McCullough Tags: Research Source Type: research

Monitoring redox stress in human airway epithelial cells exposed to woodsmoke at an air –liquid interface
Wildland fires contribute significantly to the ambient air pollution burden worldwide, causing a range of adverse health effects in exposed populations. The toxicity of woodsmoke, a complex mixture of gases, v... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - March 8, 2024 Category: Toxicology Authors: Aiman Abzhanova, Jon Berntsen, Edward R. Pennington, Lisa Dailey, Syed Masood, Ingrid George, Nina Warren, Joseph Martin, Michael D. Hays, Andrew J. Ghio, Jason P. Weinstein, Yong Ho Kim, Earl Puckett and James M. Samet Tags: Research Source Type: research

Macrophage-derived exosomal HMGB3 regulates silica-induced pulmonary inflammation by promoting M1 macrophage polarization and recruitment
Chronic inflammation and fibrosis are characteristics of silicosis, and the inflammatory mediators involved in silicosis have not been fully elucidated. Recently, macrophage-derived exosomes have been reported... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - March 7, 2024 Category: Toxicology Authors: Xiaofeng Qin, Zhiyuan Niu, Hui Chen and Yongbin Hu Tags: Research Source Type: research

Exposure to high dose of polystyrene nanoplastics causes trophoblast cell apoptosis and induces miscarriage
With rapid increase in the global use of various plastics, microplastics (MPs) and nanoplastics (NPs) pollution and their adverse health effects have attracted global attention. MPs have been detected out in h... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - March 7, 2024 Category: Toxicology Authors: Shukun Wan, Xiaoqing Wang, Weina Chen, Manli Wang, Jingsong Zhao, Zhongyan Xu, Rong Wang, Chenyang Mi, Zhaodian Zheng and Huidong Zhang Tags: Research Source Type: research

Correction: Perinatal foodborne titanium dioxide exposure-mediated dysbiosis predisposes mice to develop colitis through life
(Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - March 6, 2024 Category: Toxicology Authors: Caroline Carl é, Delphine Boucher, Luisa Morelli, Camille Larue, Ekaterina Ovtchinnikova, Louise Battut, Kawthar Boumessid, Melvin Airaud, Muriel Quaranta-Nicaise, Jean-Luc Ravanat, Gilles Dietrich, Sandrine Menard, Gérard Eberl, Nicolas Barnich, Emmanu Tags: Correction Source Type: research

Results from omic approaches in rat or mouse models exposed to inhaled crystalline silica: a systematic review
Crystalline silica (cSiO2) is a mineral found in rocks; workers from the construction or denim industries are particularly exposed to cSiO2 through inhalation. cSiO2 inhalation increases the risk of silicosis and... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - March 1, 2024 Category: Toxicology Authors: Laura Morin, Val érie Lecureur and Alain Lescoat Tags: Review Source Type: research

Zinc oxide nanoparticles exacerbate skin epithelial cell damage by upregulating pro-inflammatory cytokines and exosome secretion in M1 macrophages following UVB irradiation-induced skin injury
Zinc oxide nanoparticles (ZnONPs) are common materials used in skin-related cosmetics and sunscreen products due to their whitening and strong UV light absorption properties. Although the protective effects of... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - February 28, 2024 Category: Toxicology Authors: Bour-Jr Wang, Yu-Ying Chen, Hui-Hsuan Chang, Rong-Jane Chen, Ying-Jan Wang and Yu-Hsuan Lee Tags: Research Source Type: research

Differential pulmonary toxicity and autoantibody formation in genetically distinct mouse strains following combined exposure to silica and diesel exhaust particles
Inhalation of airborne particulate matter, such as silica and diesel exhaust particles, poses serious long-term respiratory and systemic health risks. Silica exposure can lead to silicosis and systemic autoimm... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - February 27, 2024 Category: Toxicology Authors: Lisa MF Janssen, Frauke Lemaire, Nora Fopke Marain, Steven Ronsmans, Natasja Heylen, Arno Vanstapel, Greetje Vande Velde, Jeroen AJ Vanoirbeek, Kenneth Michael Pollard, Manosij Ghosh and Peter HM Hoet Tags: Research Source Type: research

Effective density of inhaled environmental and engineered nanoparticles and its impact on the lung deposition and dosimetry
Airborne environmental and engineered nanoparticles (NPs) are inhaled and deposited in the respiratory system. The inhaled dose of such NPs and their deposition location in the lung determines their impact on ... (Source: Particle and Fibre Toxicology)
Source: Particle and Fibre Toxicology - February 17, 2024 Category: Toxicology Authors: Denisa Lizonova, Amogh Nagarkar, Philip Demokritou and Georgios A. Kelesidis Tags: Research Source Type: research