Helicobacter Pylori infection in children with cerebral palsy: A cross-sectional study
Children with cerebral palsy (CP) frequently have associated disorders and complications, including gastrointestinal problems. Helicobacter Pylori is a common infection worldwide, frequently associated with gastrointestinal manifestations. (Source: Pediatric Neurology)
Source: Pediatric Neurology - May 3, 2024 Category: Neurology Authors: Sally M. Ismael, Dina S. Atia, Salwa A. Atlam, Abeer A. Eltoukhy, Amira Hamed Darwish Tags: Research Paper Source Type: research
Pediatric Neuroglial Tumors: A Review of Ependymoma and Dysembryoplastic Neuroepithelial Tumor
Pediatric brain tumors are the most common solid malignancy in children. While categorized by their location in the central nervous system (CNS), this group of tumors is highly heterogeneous, composed of numerous different tumor types, each with a unique cell of origin, clinical behavior, and prognosis. Advances in molecular diagnostics have pushed the field of pediatric neuro-oncology forward in recent years. Tumors that were once considered a singular diagnosis are now known to be multiple entities with a unique genetic signature. (Source: Pediatric Neurology)
Source: Pediatric Neurology - May 2, 2024 Category: Neurology Authors: Melissa Arfuso, Sandeepkumar Kuril, Harshal Shah, Derek Hanson Source Type: research
Assessing the Role of Asthma on the Relationship between Neurodevelopmental Disabilities and Adverse Birth Outcomes
(s): To examine the role of asthma as an effect modifier of the association between adverse birth outcomes and neurodevelopmental disabilities (NDDs) with an emphasis on race/ethnicity. (Source: Pediatric Neurology)
Source: Pediatric Neurology - May 2, 2024 Category: Neurology Authors: Omobola Oluwafemi, Sneha Manoharan, Luyu Xie, George Pro, Rikinkumar S. Patel, George L. Delclos, Andrew Gelfand, Sarah E. Messiah, David S. Lopez, Jenil Patel Tags: Research Paper Source Type: research
Eculizumab in Adolescent Patients with Refractory Generalized Myasthenia Gravis: A Phase 3, Open-Label, Multicenter Study
This study evaluated the efficacy and safety of eculizumab, a terminal complement C5 inhibitor. (Source: Pediatric Neurology)
Source: Pediatric Neurology - April 25, 2024 Category: Neurology Authors: John F. Brandsema, Matthew Ginsberg, Hideki Hoshino, Masakazu Mimaki, Satoru Nagata, Vamshi K. Rao, Katherine Ruzhansky, Niraja Suresh, Emmanuelle Tiongson, Hideo Yamanouchi, Glen Frick, Eden Hicks, Serena Liao, James F. Howard, MG 303 Study Group Tags: Research Paper Source Type: research
Enterovirus-Related Parainfectious Acute Disseminated Encephalomyelitis Presenting with Dorsal Midbrain Syndrome: A Pediatric Case Report
An 8-year-old male patient presented to the pediatric clinic with complaints of cough, cold, lethargy, fever, restricted eye movements, and altered sensorium for one day. A detailed clinical examination revealed bilateral ophthalmoparesis, with left occulomotor nerve involvement leading to limitations of vertical gaze. The patient was referred to the ophthalmology clinic for assessment. Upon evaluation, it was observed that the child exhibited upward gaze palsy and convergence-retraction nystagmus as can be seen in Figure 1. (Source: Pediatric Neurology)
Source: Pediatric Neurology - April 25, 2024 Category: Neurology Authors: H Shafeeq Ahmed, Chinmayee J. Thrishulamurthy Tags: Correspondence Source Type: research
Sensory symptoms across the lifespan in people with cerebral palsy
To estimate prevalence of sensory symptoms in people with cerebral palsy (CP) across the lifespan. (Source: Pediatric Neurology)
Source: Pediatric Neurology - April 25, 2024 Category: Neurology Authors: Ariel M. Lyons-Warren, Danielle Guez-Barber, Sruthi P. Thomas, Evelyne K. Tantry, Aditya Mahat, Bhooma Aravamuthan, Cerebral Palsy Research Network Tags: Research Paper Source Type: research
Investigating associations between non-adherence to guideline-recommended treatment of pediatric seizures and adverse outcomes: a Canadian feasibility study
We found evidence of substantial non-adherence to guideline-recommended treatment of pediatric seizures. Medical records do not contain sufficient information to comprehensively investigate this issue. A multi-centre prospective study is the most feasible option to examine the association between non-adherence to guideline-recommended treatment and patient outcomes. (Source: Pediatric Neurology)
Source: Pediatric Neurology - April 25, 2024 Category: Neurology Authors: Meaghan Moreau, Helen Coo, Niveditha Pattathil, Vinay Kukreti, Steven C. Brooks, Anupam Sehgal Tags: Research Paper Source Type: research
Fetal Cerebral Ventriculomegaly: A Narrative Review and Practical Recommendations for Pediatric Neurologists
Fetal cerebral ventriculomegaly is one of the most common fetal neurological disorders identified prenatally by neuroimaging. The challenges in the evolving landscape of conditions like fetal cerebral ventriculomegaly involve accurate diagnosis and how best to provide prenatal counseling regarding prognosis as well as postnatal management and care of the infant. The purpose of this narrative review is to discuss the literature on fetal ventriculomegaly, including postnatal management and neurodevelopmental outcome, and to provide practice recommendations for pediatric neurologists. (Source: Pediatric Neurology)
Source: Pediatric Neurology - April 25, 2024 Category: Neurology Authors: Sonika Agarwal, Charu Venkatesan, Brigitte Vollmer, Barbara Scelsa, Monica E. Lemmon, Andrea C. Pardo, Sarah B. Mulkey, Tomo Tarui, Vatsla Dadhwal, Mark Scher, Anthony R. Hart, Dawn Gano Tags: Review Article Source Type: research
PRESenting a Challenge: Posterior Reversible Encephalopathy Syndrome (PRES) in pediatric patients of Guillain-Barr é Syndrome (GBS) a case series and review of literature
Guillain-Barre syndrome (GBS) is an autoimmune disorder characterized by demyelination of peripheral nerves. GBS-associated posterior reversible encephalopathy syndrome (PRES) is a rare and potentially life-threatening complication in the pediatric population. We aimed to report and analyze the clinical features, management, and outcomes of three cases of GBS-associated PRES in our setting in the light of the existing literature. (Source: Pediatric Neurology)
Source: Pediatric Neurology - April 25, 2024 Category: Neurology Authors: Rohini M. Surve, Kunal K. Sharma, Prachi Sharma, Roshan Nisal, Hima S. Pendharkar, Girish B. Kulkarni Tags: Short Communication Source Type: research
Epidemiology of Spinal Muscular Atrophy Based on the Results of a Large-Scale Pilot Project on 202,908 Newborns
This study presents the findings of a newborn screening (NBS) pilot project for spinal muscular atrophy (SMA) 5q in multiple regions across Russia for a period of 2022 year. The aim was to assess the feasibility and reproducibility of NBS for SMA5q in diverse populations and estimate the real prevalence of SMA5q in Russia as well as the distribution of patients with different number of SMN2 copies. (Source: Pediatric Neurology)
Source: Pediatric Neurology - April 24, 2024 Category: Neurology Authors: Irina Yu. Efimova, Rena A. Zinchenko, Andrey V. Marakhonov, Natalya V. Balinova, Kristina A. Mikhalchuk, Olga A. Shchagina, Alexander V. Polyakov, Dzhaina A. Mudaeva, Djamila H. Saydaeva, Svetlana A. Matulevich, Polina D. Parshintseca, Elena Yu. Belyashov Tags: Research Paper Source Type: research
Neurocognitive impairment in patients with Ataxia Telangiectasia and their unaffected parents: Is it similar?
This study aimed to evaluate neurocognitive functioning in patients with AT and their unaffected parents. (Source: Pediatric Neurology)
Source: Pediatric Neurology - April 21, 2024 Category: Neurology Authors: Emel Uyar, Hacer Akturk, Sevil Usanmaz, Ayca Kiykim, Ali Evren Tufan, Hande Alibas, Omer Aydiner, Ayper Somer, Ahmet Ozen, Safa Baris, Elif Karakoc-Aydiner Tags: Research Paper Source Type: research
Brain network characterization of preterm infants with bronchopulmonary dysplasia
Bronchopulmonary dysplasia (BPD) affects the microstructure of white matter in preterm infants, but its influence on the changes of the brain structural network has not been elaborated. To investigate the connectivity characteristics of the brain structural network of BPD by using diffusion tensor imaging. (Source: Pediatric Neurology)
Source: Pediatric Neurology - April 20, 2024 Category: Neurology Authors: Ying Liu, Binbin Nie, Bing Wu, Shuai Wang, Qiaozhi Ma, Tao Han, Feng Wang, Han Meng, Hao Xie, Xuetao Mu Tags: Research Paper Source Type: research
Novel genetic variants distinguishing MOG-IgG positive from MOG-IgG negative pediatric ADEM in Northern China
Acute disseminated encephalomyelitis (ADEM) is a commonphenotype in children with myelin oligodendrocyte glycoprotein IgG (MOG-IgG)-associated disease. We aimed to identify novel genetic variants that distinguish children with MOG-IgG positive ADEM (MOG-IgG+ADEM) from children with MOG-IgG negative ADEM (MOG-IgG-ADEM) using whole exome sequencing (WES) analysis. (Source: Pediatric Neurology)
Source: Pediatric Neurology - April 18, 2024 Category: Neurology Authors: Yaqiong Cui, Bo Wu, Jinying Wu, Shuyue Zhang, Pan Guo, Jianbo Shu, Dong Li, Chunquan Cai Tags: Research Paper Source Type: research
Safety of Obinutuzumab in children with autoimmune encephalitis and early B cell repopulation on rituximab.
The study objective was to report the use and safety of obinutuzumab in rituximab-resistant children with neurological inflammatory diseases. (Source: Pediatric Neurology)
Source: Pediatric Neurology - April 18, 2024 Category: Neurology Authors: A.T. Nguyen, C. Cotteret, C. Gins, E. Sarda, C. Durrleman, B. Mesples, J. Bustamante, C. Fayard, S. Cisternino, I. Desguerre, M. Aubart Tags: Research Paper Source Type: research
Identifying Lesions of the Corpus Callosum in Patients with Neurofibromatosis Type 1
To investigate the rate of lesions of the corpus callosum (CC), specifically unidentified bright objects (UBOs) and gliomas, in a large cohort of Neurofibromatosis type 1 (NF1) patients. (Source: Pediatric Neurology)
Source: Pediatric Neurology - April 17, 2024 Category: Neurology Authors: Nora Jandhyala, Mekka R. Garcia, Monica Kim, Kaleb Yohay, Devorah Segal Tags: Research Paper Source Type: research
