Pharmacokinetics of intravenous piperacillin/tazobactam among patients with peritoneal dialysis-associated peritonitis
This study employed a prospective single-dose pharmacokinetic design to assess the pharmacokinetics of IV piperacillin/tazobactam in these patients. Four patients with PD peritonitis who received an IV loading dose of 4000 mg/500 mg piperacillin/tazobactam were enrolled in this study. The concentrations of piperacillin and tazobactam in plasma, peritoneal dialysis fluid (PDF) and urine were determined by high-performance liquid chromatography. Non-compartmental methods were used for pharmacokinetic analysis. During a 6-h dwell time for chronic ambulatory peritoneal dialysis (CAPD), 9.23 ± 4.01% of the piperacillin was rec...
Source: Peritoneal Dialysis International - April 26, 2024 Category: Urology & Nephrology Authors: Taweesak Maneerot Suwikran Wongpraphairot Aroonrut Lucksiri Sutep Jaruratanasirikul Weerachai Chaijamorn Nanthawut Ninwisut Uraiwan Parinyasiri Yuttitham Suteeka Sutthiporn Pattharachayakul Source Type: research
Survival, cumulative hospital days and infectious complications in urgent-start PD compared with urgent-start HD
CONCLUSIONS: Patient survival, cumulative first-year hospital care days and total KRT-related infection rate at 3 months and 1-year follow-up are similar between urgent-start PD and urgent-start HD patients. Furthermore, CVC insertion rate is associated with incident blood culture-positive bacteraemia and increased cumulative first-year hospital care days.PMID:38661183 | DOI:10.1177/08968608241244939 (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - April 25, 2024 Category: Urology & Nephrology Authors: Jonna Virtanen Maija Heiro Niina Koivuviita Eliisa L öyttyniemi Mikko J J ärvisalo Risto Tertti Kaj Mets ärinne Tapio Hellman Source Type: research
Exploring clinical practice guidelines in PD: When to guide and when to draw the line
Perit Dial Int. 2024 Apr 21:8968608241245900. doi: 10.1177/08968608241245900. Online ahead of print.NO ABSTRACTPMID:38644579 | DOI:10.1177/08968608241245900 (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - April 22, 2024 Category: Urology & Nephrology Authors: Antoine Lanot Annabel Boyer Thierry Lobbedez Cl émence Béchade Source Type: research
Pyogenic liver abscesses in peritoneal dialysis patients: A single-centre retrospective case series
This study aims to describe the characteristics, management and outcomes of liver abscesses in PD patients from a retrospective review of prevalent PD patients on follow-up at Tan Tock Seng Hospital between 1st January 2016 and 30th June 2021. A total of 11/383 PD patients (2.9%) were treated for liver abscesses. Most were diabetic (n =10, 90.9%), with a median PD vintage of 541 days (interquartile range: 310-931 days). Fever (n = 7, 63.6%), bacteraemia (n = 7, 63.6%) and concomitant PD peritonitis (n = 7, 63.6%) were the most common presenting symptoms. Majority of patients underwent radiological aspiration of abscess in ...
Source: Peritoneal Dialysis International - April 22, 2024 Category: Urology & Nephrology Authors: Regina Shaoying Lim Yong Pey See Source Type: research
Exploring clinical practice guidelines in PD: When to guide and when to draw the line
Perit Dial Int. 2024 Apr 21:8968608241245900. doi: 10.1177/08968608241245900. Online ahead of print.NO ABSTRACTPMID:38644579 | DOI:10.1177/08968608241245900 (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - April 22, 2024 Category: Urology & Nephrology Authors: Antoine Lanot Annabel Boyer Thierry Lobbedez Cl émence Béchade Source Type: research
Pyogenic liver abscesses in peritoneal dialysis patients: A single-centre retrospective case series
This study aims to describe the characteristics, management and outcomes of liver abscesses in PD patients from a retrospective review of prevalent PD patients on follow-up at Tan Tock Seng Hospital between 1st January 2016 and 30th June 2021. A total of 11/383 PD patients (2.9%) were treated for liver abscesses. Most were diabetic (n =10, 90.9%), with a median PD vintage of 541 days (interquartile range: 310-931 days). Fever (n = 7, 63.6%), bacteraemia (n = 7, 63.6%) and concomitant PD peritonitis (n = 7, 63.6%) were the most common presenting symptoms. Majority of patients underwent radiological aspiration of abscess in ...
Source: Peritoneal Dialysis International - April 22, 2024 Category: Urology & Nephrology Authors: Regina Shaoying Lim Yong Pey See Source Type: research
Corrigendum to 2022 ISPD Peritonitis Guidelines: 2022 update on prevention and treatment
Perit Dial Int. 2024 Apr 21:8968608241251453. doi: 10.1177/08968608241251453. Online ahead of print.NO ABSTRACTPMID:38643390 | DOI:10.1177/08968608241251453 (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - April 21, 2024 Category: Urology & Nephrology Source Type: research
Health-related quality of life in paediatric patients on peritoneal dialysis: Data from a tertiary centre
Perit Dial Int. 2024 Apr 17:8968608241241177. doi: 10.1177/08968608241241177. Online ahead of print.ABSTRACTKidney failure has a negative impact on both children and families' quality of life (QOL). We evaluated the burden of home peritoneal dialysis (PD) using two local questionnaires and the French version of PedsQL3.0 end-stage kidney disease module and family impact module. Data are expressed as median (min-max). We reviewed the charts of 12 patients, at a median age of 8.8 (1.2-16.7) years, undergoing maintenance PD for 8 (1-42) months. Parathyroid hormone and haemoglobin levels were 215 (17-606) ng/L and 117 (104-141...
Source: Peritoneal Dialysis International - April 18, 2024 Category: Urology & Nephrology Authors: Elias Hajj Marijke Awouters Melodie Mosca Sacha Flammier Sarra Rachedi Justine Bacchetta Aurelie De Mul Bruno Ranchin Source Type: research
Is social deprivation associated with the peritoneal dialysis outcomes? A cohort study with REIN registry data
CONCLUSION: In PD patients, social deprivation was not associated with death or the composite event of death or transfer to HD. Socially deprived individuals had a greater risk of transfer to HD and lower access to kidney transplantation in the competing risk analysis.PMID:38632672 | DOI:10.1177/08968608241237685 (Source: Peritoneal Dialysis International)
Source: Peritoneal Dialysis International - April 18, 2024 Category: Urology & Nephrology Authors: Steve Biko Tobada Val érie Chatelet Clemence Bechade Antoine Lanot Annabel Boyer C écile Couchoud Fatouma Toure Sabrina Boime Thierry Lobbedez Mathilde Beaumier Source Type: research
Health-related quality of life in paediatric patients on peritoneal dialysis: Data from a tertiary centre
Perit Dial Int. 2024 Apr 17:8968608241241177. doi: 10.1177/08968608241241177. Online ahead of print.ABSTRACTKidney failure has a negative impact on both children and families' quality of life (QOL). We evaluated the burden of home peritoneal dialysis (PD) using two local questionnaires and the French version of PedsQL3.0 end-stage kidney disease module and family impact module. Data are expressed as median (min-max). We reviewed the charts of 12 patients, at a median age of 8.8 (1.2-16.7) years, undergoing maintenance PD for 8 (1-42) months. Parathyroid hormone and haemoglobin levels were 215 (17-606) ng/L and 117 (104-141...
Source: Peritoneal Dialysis International - April 18, 2024 Category: Urology & Nephrology Authors: Elias Hajj Marijke Awouters Melodie Mosca Sacha Flammier Sarra Rachedi Justine Bacchetta Aurelie De Mul Bruno Ranchin Source Type: research
