Nutrient remobilization and C:N:P stoichiometry in response to elevated CO < sub > 2 < /sub > and low phosphorus availability in rice cultivars introgressed with and without Pup1
Plant Physiol Biochem. 2024 Apr 23;210:108657. doi: 10.1016/j.plaphy.2024.108657. Online ahead of print.ABSTRACTThe continuously rising atmospheric CO2 concentration potentially increase plant growth through stimulating C metabolism; however, plant C:N:P stoichiometry in response to elevated CO2 (eCO2) under low P stress remains largely unknown. We investigated the combined effect of eCO2 and low phosphorus on growth, yield, C:N:P stoichiometry, and remobilization in rice cv. Kasalath (aus type), IR64 (a mega rice variety), and IR64-Pup1 (Pup1 QTL introgressed IR64). In response to eCO2 and low P, the C accumulation increa...
Source: Physiological Research - April 26, 2024 Category: Physiology Authors: Sandeep Sharma D H Raviteja Tarun Kumar Prem S Bindraban Renu Pandey Source Type: research
Biocompatible silver nanoparticles as nanopriming mediators for improved rice germination and root growth: A transcriptomic perspective
Plant Physiol Biochem. 2024 Apr 18;210:108645. doi: 10.1016/j.plaphy.2024.108645. Online ahead of print.ABSTRACTSilver nanoparticles (AgNPs) have an important role in agriculture since they have several applications that are essential for the enhanced yield of crops. Furthermore, they act as nano-pesticides, delivering a proper dose to the target plants without releasing unwanted pesticides into the environment. Upholding the sustainable nano agriculture, biocompatible silver nanoparticles were synthesised utilising Piper colubrinum Link. leaf extract. Different characterization methods (TEM, EDX and XRD) revealed that AgN...
Source: Physiological Research - April 25, 2024 Category: Physiology Authors: R Santhoshkumar A Hima Parvathy E V Soniya Source Type: research
Biocompatible silver nanoparticles as nanopriming mediators for improved rice germination and root growth: A transcriptomic perspective
Plant Physiol Biochem. 2024 Apr 18;210:108645. doi: 10.1016/j.plaphy.2024.108645. Online ahead of print.ABSTRACTSilver nanoparticles (AgNPs) have an important role in agriculture since they have several applications that are essential for the enhanced yield of crops. Furthermore, they act as nano-pesticides, delivering a proper dose to the target plants without releasing unwanted pesticides into the environment. Upholding the sustainable nano agriculture, biocompatible silver nanoparticles were synthesised utilising Piper colubrinum Link. leaf extract. Different characterization methods (TEM, EDX and XRD) revealed that AgN...
Source: Physiological Research - April 25, 2024 Category: Physiology Authors: R Santhoshkumar A Hima Parvathy E V Soniya Source Type: research
Redox Status as a Key Driver of Healthy Pancreatic Beta-Cells
Physiol Res. 2024 Apr 22. Online ahead of print.ABSTRACTRedox status plays a multifaceted role in the intricate physiology and pathology of pancreatic beta-cells, the pivotal regulators of glucose homeostasis through insulin secretion. They are highly responsive to changes in metabolic cues where reactive oxygen species are part of it, all arising from nutritional intake. These molecules not only serve as crucial signaling intermediates for insulin secretion but also participate in the nuanced heterogeneity observed within the beta-cell population. A central aspect of beta-cell redox biology revolves around the localized p...
Source: Physiological Research - April 22, 2024 Category: Physiology Authors: B Holendov á Š Benáková M K řivonosková L Plecit á-Hlavatá Source Type: research
Mitochondrial Physiology of Cellular Redox Regulations
Physiol Res. 2024 Apr 22. Online ahead of print.ABSTRACTMitochondria (mt) represent the vital hub of the molecular physiology of the cell, being decision-makers in cell life/death and information signaling, including major redox regulations and redox signaling. Now we review recent advances in understanding mitochondrial redox homeostasis, including superoxide sources and H2O2 consumers, i.e., antioxidant mechanisms, as well as exemplar situations of physiological redox signaling, including the intramitochondrial one and mt-to-cytosol redox signals, which may be classified as acute and long-term signals. This review exempl...
Source: Physiological Research - April 22, 2024 Category: Physiology Authors: P Je žek A Dlaskov á H Engstov á J Špačková J Tauber P Pr ůchová E Kloppel O Mozheitova M Jab ůrek Source Type: research
Mathematical Models of Diffusion in Physiology
Physiol Res. 2024 Apr 22. Online ahead of print.ABSTRACTDiffusion is a mass transport phenomenon caused by chaotic thermal movements of molecules. Studying the transport in specific domain is simplified by using evolutionary differential equations for local concentration of the molecules instead of complete information on molecular paths [1]. Compounds in a fluid mixture tend to smooth out its spatial concentration inhomogeneities by diffusion. Rate of the transport is proportional to the concentration gradient and coefficient of diffusion of the compound in ordinary diffusion. The evolving concentration profile c(x,t) is ...
Source: Physiological Research - April 22, 2024 Category: Physiology Authors: J Jan áček Source Type: research
Look for the Scaffold: Multifaceted Regulation of Enzyme Activity by 14-3-3 Proteins
Physiol Res. 2024 Apr 22. Online ahead of print.ABSTRACTEnzyme activity is regulated by several mechanisms, including phosphorylation. Phosphorylation is a key signal transduction process in all eukaryotic cells and is thus crucial for virtually all cellular processes. In addition to its direct effect on protein structure, phosphorylation also affects protein-protein interactions, such as binding to scaffolding 14-3-3 proteins, which selectively recognize phosphorylated motifs. These interactions then modulate the catalytic activity, cellular localisation and interactions of phosphorylated enzymes through different mechani...
Source: Physiological Research - April 22, 2024 Category: Physiology Authors: V Ob šilová T Ob šil Source Type: research
Redox Status as a Key Driver of Healthy Pancreatic Beta-Cells
Physiol Res. 2024 Apr 22. Online ahead of print.ABSTRACTRedox status plays a multifaceted role in the intricate physiology and pathology of pancreatic beta-cells, the pivotal regulators of glucose homeostasis through insulin secretion. They are highly responsive to changes in metabolic cues where reactive oxygen species are part of it, all arising from nutritional intake. These molecules not only serve as crucial signaling intermediates for insulin secretion but also participate in the nuanced heterogeneity observed within the beta-cell population. A central aspect of beta-cell redox biology revolves around the localized p...
Source: Physiological Research - April 22, 2024 Category: Physiology Authors: B Holendov á Š Benáková M K řivonosková L Plecit á-Hlavatá Source Type: research
Mitochondrial Physiology of Cellular Redox Regulations
Physiol Res. 2024 Apr 22. Online ahead of print.ABSTRACTMitochondria (mt) represent the vital hub of the molecular physiology of the cell, being decision-makers in cell life/death and information signaling, including major redox regulations and redox signaling. Now we review recent advances in understanding mitochondrial redox homeostasis, including superoxide sources and H2O2 consumers, i.e., antioxidant mechanisms, as well as exemplar situations of physiological redox signaling, including the intramitochondrial one and mt-to-cytosol redox signals, which may be classified as acute and long-term signals. This review exempl...
Source: Physiological Research - April 22, 2024 Category: Physiology Authors: P Je žek A Dlaskov á H Engstov á J Špačková J Tauber P Pr ůchová E Kloppel O Mozheitova M Jab ůrek Source Type: research
Mathematical Models of Diffusion in Physiology
Physiol Res. 2024 Apr 22. Online ahead of print.ABSTRACTDiffusion is a mass transport phenomenon caused by chaotic thermal movements of molecules. Studying the transport in specific domain is simplified by using evolutionary differential equations for local concentration of the molecules instead of complete information on molecular paths [1]. Compounds in a fluid mixture tend to smooth out its spatial concentration inhomogeneities by diffusion. Rate of the transport is proportional to the concentration gradient and coefficient of diffusion of the compound in ordinary diffusion. The evolving concentration profile c(x,t) is ...
Source: Physiological Research - April 22, 2024 Category: Physiology Authors: J Jan áček Source Type: research
Look for the Scaffold: Multifaceted Regulation of Enzyme Activity by 14-3-3 Proteins
Physiol Res. 2024 Apr 22. Online ahead of print.ABSTRACTEnzyme activity is regulated by several mechanisms, including phosphorylation. Phosphorylation is a key signal transduction process in all eukaryotic cells and is thus crucial for virtually all cellular processes. In addition to its direct effect on protein structure, phosphorylation also affects protein-protein interactions, such as binding to scaffolding 14-3-3 proteins, which selectively recognize phosphorylated motifs. These interactions then modulate the catalytic activity, cellular localisation and interactions of phosphorylated enzymes through different mechani...
Source: Physiological Research - April 22, 2024 Category: Physiology Authors: V Ob šilová T Ob šil Source Type: research
Hemodynamic Mechanisms Initiating Salt-Sensitive Hypertension in Rat Model of Primary Aldosteronism
Physiol Res. 2024 Apr 18. Online ahead of print.ABSTRACTFew studies have investigated the hemodynamic mechanism whereby primary hyperaldosteronism causes hypertension. The traditional view holds that hyperaldosteronism initiates hypertension by amplifying salt-dependent increases in cardiac output (CO) by promoting increases in sodium retention and blood volume. Systemic vascular resistance (SVR) is said to increase only as a secondary consequence of the increased CO and blood pressure. Recently, we investigated the primary hemodynamic mechanism whereby hyperaldosteronism promotes salt sensitivity and initiation of salt-de...
Source: Physiological Research - April 18, 2024 Category: Physiology Authors: M Pravenec P Mlejnek M Šimáková J Šilhavý Source Type: research
Epitranscriptomic Regulations in the Heart
Physiol Res. 2024 Apr 18. Online ahead of print.ABSTRACTRNA modifications affect key stages of the RNA life cycle, including splicing, export, decay, and translation. Epitranscriptomic regulations therefore significantly influence cellular physiology and pathophysiology. Here, we selected some of the most abundant modifications and reviewed their roles in the heart and in cardiovascular diseases: N6-methyladenosine (m6A), N6,2'-O-dimethyladenosine (m6Am), N1-methyladenosine (m1A), pseudouridine (?), 5 methylcytidine (m5C), and inosine (I). Dysregulation of epitranscriptomic machinery affecting these modifications vastly ch...
Source: Physiological Research - April 18, 2024 Category: Physiology Authors: D Benak F Kolar M Hlavackova Source Type: research
Muscarinic Receptors in Cardioprotection and Vascular Tone Regulation
Physiol Res. 2024 Apr 18. Online ahead of print.ABSTRACTMuscarinic acetylcholine receptors are metabotropic G-protein coupled receptors. Muscarinic receptors in the cardiovascular system play a central role in its regulation. Particularly M2 receptors slow down the heart rate by reducing the impulse conductivity through the atrioventricular node. In general, activation of muscarinic receptors has sedative effects on the cardiovascular system, including vasodilation, negative chronotropic and inotropic effects on the heart, and cardioprotective effects, including antifibrillatory effects. First, we review the signaling of i...
Source: Physiological Research - April 18, 2024 Category: Physiology Authors: E Dolej ší A Janou šková J Jakub ík Source Type: research
Circadian Disruption as a Risk Factor for Development of Cardiovascular and Metabolic Disorders - From Animal Models to Human Population
Physiol Res. 2024 Apr 18. Online ahead of print.ABSTRACTThe lifestyle of human society is drifting apart from the natural environmental cycles that have influenced it since its inception. These cycles were fundamental in structuring the daily lives of people in the pre-industrial era, whether they were seasonal or daily. Factors that disrupt the regularity of human behaviour and its alignment with solar cycles, such as late night activities accompanied with food intake, greatly disturb the internal temporal organization in the body. This is believed to contribute to the rise of the so-called diseases of civilization. In th...
Source: Physiological Research - April 18, 2024 Category: Physiology Authors: A Sumov á M Sl ádek Source Type: research
