Semaglutide combined with empagliflozin vs. monotherapy for non-alcoholic fatty liver disease in type 2 diabetes: Study protocol for a randomized clinical trial
This study has been registered with Chinese Clinical Trial Registry (ChiCTR2300070674). (Source: PLoS One)
Source: PLoS One - May 3, 2024 Category: Biomedical Science Authors: Yu-Hao Lin Source Type: research
Maternal distress during the COVID-19 outbreak: A socio-ecological perspective
ConclusionsThe findings highlight the intersection of individual, familial, and environmental factors in mothers ’ mental health during crises. (Source: PLoS One)
Source: PLoS One - May 3, 2024 Category: Biomedical Science Authors: Mor Keleynikov Source Type: research
Role of the left posterior middle temporal gyrus in shape recognition and its reconstruction during drawing: A study combining transcranial magnetic stimulation and functional near infrared spectroscopy
by Nakako Okamoto, Akitoshi Seiyama, Shota Hori, Satoru Takahashi
There are numerous reports of enhanced or emerged visual arts abilities in patients with semantic impairment. These reports led to the theory that a loss of function on the language side of the brain can result in changes of ability to draw and/or to paint. Further, the left posterior middle tempo ral gyrus (l-pMTG) has been revealed to contribute to the higher control semantic mechanisms with objects recognition and integration of visual information, within a widely distributed network of the left hemisphere. Nevertheless, the theory has not been fully stu...
Source: PLoS One - May 3, 2024 Category: Biomedical Science Authors: Nakako Okamoto Source Type: research
Internet use and its association with physical activity among adolescents in Beni Municipality, Myagdi, Nepal
ConclusionThe study concludes that over two-thirds of adolescents were addicted to the Internet, and three-fourths were inadequately physically active, with late adolescents being more affected than middle adolescents. Inadequate physical activity was associated with various factors, including family type, monthly family income, monthly pocket money, father ’s occupation, type of school, type of internet access, and Internet Addiction Test (IAT) score. Internet-addicted adolescents were found to be more likely to be physically inactive. (Source: PLoS One)
Source: PLoS One - May 3, 2024 Category: Biomedical Science Authors: Shristi K. C. Source Type: research
Effects of systemic inflammation on the network oscillation in the anterior cingulate cortex and cognitive behavior
by Ayumi Hirao, Yasushi Hojo, Gen Murakami, Rina Ito, Miki Hashizume, Takayuki Murakoshi, Naonori Uozumi
Network oscillation in the anterior cingulate cortex (ACC) plays a key role in attention, novelty detection and anxiety; however, its involvement in cognitive impairment caused by acute systemic inflammation is unclear. To investigate the acute effects of systemic inflammation on ACC network oscil lation and cognitive function, we analyzed cytokine level and cognitive performance as well as network oscillation in the mouse ACC Cg1 region, within 4 hours after lipopolysaccharide (LPS, 30 μg/kg) administration. While th...
Source: PLoS One - May 3, 2024 Category: Biomedical Science Authors: Ayumi Hirao Source Type: research
Why does the number of antenatal care visits in Ethiopia remain low?: A Bayesian multilevel approach
ConclusionOverall, 26.5% of pregnant women do not have ANC visits during their pregnancy, and 3% of women have eight-time ANC visits. This result is much lower as compared to WHO ’s recommendation, which states that all pregnant women should have at least eight ANC visits. In this study, the ages of the women 25–28, 29–33, and ≥34 years, being a primary school, secondary school, and above, delivered in a health facility, delivered with caesarian section, multiple pre gnancies, rich, middle and poor wealth index, were significantly associated with the higher number of ANC visits, while households with large family s...
Source: PLoS One - May 3, 2024 Category: Biomedical Science Authors: Daniel Atlaw Source Type: research
A qualitative exploration of the experiences of pregnant women living with obesity and accessing antenatal care
This study explored the experiences of pregnant women living with obesity in accessing antenatal care. Seventeen women completed a semi-structured interview. Transcripts were analysed thematically. Four themes were developed: 1) antenatal care is inconsistent, 2) additional support is needed, 3) women feel judged about their weight, and 4) weight cycling is highly prevalent. Findings suggest that pregnant women living with obesity often experience weight bias from HCPs, feel judged because of thei r weight and are left feeling confused and overlooked. Women reported inconsistencies in advice and care offered and acknowledg...
Source: PLoS One - May 3, 2024 Category: Biomedical Science Authors: Margaret Charnley Source Type: research
Grandiose narcissism associates with higher cognitive performance under stress through more efficient attention distribution: An eye-tracking study
by Vasilena Stefanova, Christoph Scheepers, Paul Wilson, Kostas A. Papageorgiou
Narcissism is a part of the Dark Triad that consists also of the traits of Machiavellianism and psychopathy. Two main types of narcissism exist: grandiose and vulnerable narcissism. Being a Dark Triad trait, narcissism is typically associated with negative outcomes. However, recent research sugges ts that at least the grandiose type may be linked (directly or indirectly) to positive outcomes including lower levels of psychopathology, higher school grades in adolescents, deeper and more strategic learning in university students and higher cogni...
Source: PLoS One - May 3, 2024 Category: Biomedical Science Authors: Vasilena Stefanova Source Type: research
Investigating the nature of open science practices across complementary, alternative, and integrative medicine journals: An audit
ConclusionWhile several studies have audited open science practices across discipline-specific journals, none have focused on CAIM journals. The results of this study indicate that CAIM journals provide minimal guidelines to encourage or require authors to adhere to open science practices and there is an opportunity to improve the use of open science practices in the field. (Source: PLoS One)
Source: PLoS One - May 3, 2024 Category: Biomedical Science Authors: Jeremy Y. Ng Source Type: research
Comparison of the efficacy and complications of tolterodine and α-adrenergic receptor blockers in improving ureteral stent-related symptoms: A systematic review and meta-analysis
ConclusionThis meta-analysis suggests that tolterodine is superior to α-adrenergic receptor blockers in improving physical pain symptoms after ureteral stent placement, while α-adrenergic receptor blockers are more effective than tolterodine in enhancing work performance. Additionally, the incidence of dry mouth is higher with the use of tolterodine compared to α-a drenergic receptor blockers. However, higher-quality randomized controlled trials are needed to further investigate this issue. (Source: PLoS One)
Source: PLoS One - May 3, 2024 Category: Biomedical Science Authors: Ming Liu Source Type: research
Barriers and facilitators of adherence to low-dose aspirin during pregnancy: A co-produced systematic review and COM-B framework synthesis of qualitative evidence
ConclusionsThe COM-B framework allowed for detailed mapping of key factors shaping different phases of adherence in behavioural change terms and now provides a solid foundation for the development of a behavioural intervention. Although potential intervention elements could be suggested based on the results of this synthesis, additional co-production work is needed to define elements and plan for the delivery of the future intervention. Trial registrationPROSPERO CRD42022359718. https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022359718. (Source: PLoS One)
Source: PLoS One - May 3, 2024 Category: Biomedical Science Authors: Raya Vinogradov Source Type: research
Oral glucose tolerance test clearance in type 2 diabetes patients who underwent remission following intense lifestyle modification: A quasi-experimental study
by Pramod Tripathi, Nidhi Kadam, Diptika Tiwari, Anagha Vyawahare, Baby Sharma, Thejas Kathrikolly, Maheshkumar Kuppusamy, Venugopal Vijayakumar
Achieving diabetes remission (HbA1c (Source: PLoS One)
Source: PLoS One - May 3, 2024 Category: Biomedical Science Authors: Pramod Tripathi Source Type: research
Human-Derived collagen hydrogel as an antibiotic vehicle for topical treatment of bacterial biofilms
This study aims to assess the capacity of human -derived collagen hydrogel to provide sustained antibiotic release to disrupt bacterial biofilms and decrease bacterial load while maintaining host cell viability and scaffold integrity. Human collagen harvested from flexor tendons underwent processing to yield a gellable liquid, and subsequently wa s combined with varying concentrations of gentamicin (50–500 mg/L) or clindamycin (10–100 mg/L). The elution kinetics of antibiotics from the hydrogel were analyzed using liquid chromatography-mass spectrometry. The gel was used to topically treat Methicillin-resistantStaphylo...
Source: PLoS One - May 3, 2024 Category: Biomedical Science Authors: Evan Jarman Source Type: research
The effects of neck exercise in comparison to passive or no intervention on quantitative sensory testing measurements in adults with chronic neck pain: A systematic review
by Daniel Osborne, Ferozkhan Jadhakhan, Deborah Falla
BackgroundPrevious systematic reviews have identified the benefits of exercise for chronic neck pain on subjective reports of pain, but not with objective measures such as quantitative sensory testing (QST). A systematic review was conducted to identify the effects of neck specific exercise on QST measures in adults with chronic neck pain to synthesise existing literature and provide clinical recommendations. MethodsThe study protocol was registered prospectively with PROSPERO (PROSPERO CRD42021297383). For both randomised and non-randomised trials, the following databa...
Source: PLoS One - May 3, 2024 Category: Biomedical Science Authors: Daniel Osborne Source Type: research
Prevalence of oral rehydration solution use and its determinants in the treatment of diarrhea among under-five children in sub-Saharan Africa
This study examined the factors associated with ORS use for children with diarrhea in the sub-region. MethodsDemographic and Health Surveys (DHS) data sets of 31 countries in sub-Saharan Africa were used in this study. The data involved 30,102 under-five children with diarrhea. The multivariable analysis involved binary logistic regression. ResultsPrevalence of ORS use was 38% in sub-Saharan Africa with countries such as Namibia (71.8%), Zambia (66.4%) and Malawi (63.8%) having the highest rates. Use of ORS was most common among children whose mothers had secondary or higher education (45%), were exposed to media (41%) and...
Source: PLoS One - May 3, 2024 Category: Biomedical Science Authors: Sulaimon T. Adedokun Source Type: research
