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Patient-reported outcomes after personalised dose-escalation for stage II-III non-small-cell lung cancer patients: Results from the randomised ARTFORCE PET-Boost trial
CONCLUSION: In patients with LA-NSCLC treated with two dose-escalation strategies, the average patient-reported HRQoL remained stable in both groups, despite frequent patient-reported symptoms, including dyspnoea, dysphagia, and fatigue.PMID:38663582 | DOI:10.1016/j.radonc.2024.110312 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 25, 2024 Category: Radiology Authors: Saskia A Cooke Jos é S A Belderbos Bart Reymen Maarten Lambrecht Gitte Fredberg Persson Corinne Faivre-Finn Edith M T Dieleman Judi N A van Diessen Jan-Jakob Sonke Dirk de Ruysscher Source Type: research

Partially Ablative Body Radiotherapy (PABR): A novel approach for palliative radiotherapy of locally advanced bulky unresectable sarcomas
Radiother Oncol. 2024 Apr 21:110275. doi: 10.1016/j.radonc.2024.110275. Online ahead of print.NO ABSTRACTPMID:38653378 | DOI:10.1016/j.radonc.2024.110275 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 23, 2024 Category: Radiology Authors: Kelvin Ken Yu Adam Yeo Samuel Ngan Julie Chu David Chang Shankar Siva Aaron Wong Tomas Kron Nick Hardcastle Mathieu Gaudreault Therese Chesson Siena Williams Mark Burns Sarat Chander Source Type: research

Towards a European prospective data registry for particle therapy
Radiother Oncol. 2024 Apr 21;196:110293. doi: 10.1016/j.radonc.2024.110293. Online ahead of print.ABSTRACTThe evidence for the value of particle therapy (PT) is still sparse. While randomized trials remain a cornerstone for robust comparisons with photon-based radiotherapy, data registries collecting real-world data can play a crucial role in building evidence for new developments. This Perspective describes how the European Particle Therapy Network (EPTN) is actively working on establishing a prospective data registry encompassing all patients undergoing PT in European centers. Several obstacles and hurdles are discussed,...
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 23, 2024 Category: Radiology Authors: Cai Grau Alexandru Dasu Esther G C Troost Karin Haustermans Damien C Weber Johannes A Langendijk Vincent Gregoire Ester Orlandi Juliette Thariat Neige Journy Abdulhamid Chaikh Aurelie Isambert Barbara Alicja Jereczek-Fossa Ana Vaniqui Pavel Vitek Renata K Source Type: research

Durvalumab impacts progression-free survival while high-dose radiation & gt;66  Gy improves local control without excess toxicity in unresectable NSCLC stage III: Real-world data from the Austrian radio-oncological lung cancer study association registry (ALLSTAR)
CONCLUSION: While Durvalumab impacts PFS, LC can be improved by total radiation doses > 66 Gy without excess toxicity.PMID:38653380 | DOI:10.1016/j.radonc.2024.110294 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 23, 2024 Category: Radiology Authors: Franz Zehentmayr Petra Feurstein Elvis Ruznic Brigitte Langer Brane Grambozov Marisa Klebermass Herbert H üpfel Johann Feichtinger Danijela Minasch Martin Heilmann Barbara Breitfelder Claudia Steffal Gisela Gastinger-Grass Karoline Kirchhammer Margit Kaz Source Type: research

Partially Ablative Body Radiotherapy (PABR): A novel approach for palliative radiotherapy of locally advanced bulky unresectable sarcomas
Radiother Oncol. 2024 Apr 21:110275. doi: 10.1016/j.radonc.2024.110275. Online ahead of print.NO ABSTRACTPMID:38653378 | DOI:10.1016/j.radonc.2024.110275 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 23, 2024 Category: Radiology Authors: Kelvin Ken Yu Adam Yeo Samuel Ngan Julie Chu David Chang Shankar Siva Aaron Wong Tomas Kron Nick Hardcastle Mathieu Gaudreault Therese Chesson Siena Williams Mark Burns Sarat Chander Source Type: research

Towards a European prospective data registry for particle therapy
Radiother Oncol. 2024 Apr 21:110293. doi: 10.1016/j.radonc.2024.110293. Online ahead of print.ABSTRACTThe evidence for the value of particle therapy (PT) is still sparse. While randomized trials remain a cornerstone for robust comparisons with photon-based radiotherapy, data registries collecting real-world data can play a crucial role in building evidence for new developments. This Perspective describes how the European Particle Therapy Network (EPTN) is actively working on establishing a prospective data registry encompassing all patients undergoing PT in European centers. Several obstacles and hurdles are discussed, for...
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 23, 2024 Category: Radiology Authors: Cai Grau Alexandru Dasu Esther G C Troost Karin Haustermans Damien C Weber Johannes A Langendijk Vincent Gregoire Ester Orlandi Juliette Thariat Neige Journy Abdulhamid Chaikh Aurelie Isambert Barbara Alicja Jereczek-Fossa Ana Vaniqui Pavel Vitek Renata K Source Type: research

Durvalumab impacts progression-free survival while high-dose radiation & gt;66  Gy improves local control without excess toxicity in unresectable NSCLC stage III: Real-world data from the Austrian radio-oncological lung cancer study association registry (ALLSTAR)
CONCLUSION: While Durvalumab impacts PFS, LC can be improved by total radiation doses > 66 Gy without excess toxicity.PMID:38653380 | DOI:10.1016/j.radonc.2024.110294 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 23, 2024 Category: Radiology Authors: Franz Zehentmayr Petra Feurstein Elvis Ruznic Brigitte Langer Brane Grambozov Marisa Klebermass Herbert H üpfel Johann Feichtinger Danijela Minasch Martin Heilmann Barbara Breitfelder Claudia Steffal Gisela Gastinger-Grass Karoline Kirchhammer Margit Kaz Source Type: research

Partially Ablative Body Radiotherapy (PABR): A novel approach for palliative radiotherapy of locally advanced bulky unresectable sarcomas
Radiother Oncol. 2024 Apr 21:110275. doi: 10.1016/j.radonc.2024.110275. Online ahead of print.NO ABSTRACTPMID:38653378 | DOI:10.1016/j.radonc.2024.110275 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 23, 2024 Category: Radiology Authors: Kelvin Ken Yu Adam Yeo Samuel Ngan Julie Chu David Chang Shankar Siva Aaron Wong Tomas Kron Nick Hardcastle Mathieu Gaudreault Therese Chesson Siena Williams Mark Burns Sarat Chander Source Type: research

Towards a European prospective data registry for particle therapy
Radiother Oncol. 2024 Apr 21:110293. doi: 10.1016/j.radonc.2024.110293. Online ahead of print.ABSTRACTThe evidence for the value of particle therapy (PT) is still sparse. While randomized trials remain a cornerstone for robust comparisons with photon-based radiotherapy, data registries collecting real-world data can play a crucial role in building evidence for new developments. This Perspective describes how the European Particle Therapy Network (EPTN) is actively working on establishing a prospective data registry encompassing all patients undergoing PT in European centers. Several obstacles and hurdles are discussed, for...
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 23, 2024 Category: Radiology Authors: Cai Grau Alexandru Dasu Esther G C Troost Karin Haustermans Damien C Weber Johannes A Langendijk Vincent Gregoire Ester Orlandi Juliette Thariat Neige Journy Abdulhamid Chaikh Aurelie Isambert Barbara Alicja Jereczek-Fossa Ana Vaniqui Pavel Vitek Renata K Source Type: research

Durvalumab impacts progression-free survival while high-dose radiation & gt;66  Gy improves local control without excess toxicity in unresectable NSCLC stage III: Real-world data from the Austrian radio-oncological lung cancer study association registry (ALLSTAR)
CONCLUSION: While Durvalumab impacts PFS, LC can be improved by total radiation doses > 66 Gy without excess toxicity.PMID:38653380 | DOI:10.1016/j.radonc.2024.110294 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 23, 2024 Category: Radiology Authors: Franz Zehentmayr Petra Feurstein Elvis Ruznic Brigitte Langer Brane Grambozov Marisa Klebermass Herbert H üpfel Johann Feichtinger Danijela Minasch Martin Heilmann Barbara Breitfelder Claudia Steffal Gisela Gastinger-Grass Karoline Kirchhammer Margit Kaz Source Type: research

Minimum and optimal requirements for a safe clinical implementation of ultra-high dose rate radiotherapy: A focus on patient's safety and radiation protection
Radiother Oncol. 2024 Apr 20:110291. doi: 10.1016/j.radonc.2024.110291. Online ahead of print.NO ABSTRACTPMID:38648991 | DOI:10.1016/j.radonc.2024.110291 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 22, 2024 Category: Radiology Authors: Cristina Garibaldi Sam Beddar Nicola Bizzocchi Till Tobias B öhlen Charoula Iliaskou Rapha ël Moeckli Serena Psoroulas Anna Subiel Paige A Taylor Frank Van den Heuvel Verdi Vanreusel Dirk Verellen Source Type: research

Partially Ablative Body Radiotherapy (PABR): A novel approach for palliative radiotherapy of locally advanced bulky unresectable sarcomas. In regard to Yu et al
Radiother Oncol. 2024 Apr 20:110274. doi: 10.1016/j.radonc.2024.110274. Online ahead of print.NO ABSTRACTPMID:38648992 | DOI:10.1016/j.radonc.2024.110274 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 22, 2024 Category: Radiology Authors: Aysenur Elmali Erkan Topkan Cem Onal Source Type: research

Comments on "Radiotherapy alone versus concurrent chemoradiotherapy in patients with stage II and T3N0 nasopharyngeal carcinoma with adverse features: A propensity score-matched cohort study"
Radiother Oncol. 2024 Apr 20:110292. doi: 10.1016/j.radonc.2024.110292. Online ahead of print.NO ABSTRACTPMID:38648993 | DOI:10.1016/j.radonc.2024.110292 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 22, 2024 Category: Radiology Authors: Caglayan Selenge Beduk Esen Gizem Nur Can Berna Akkus Yildirim Source Type: research

Radiation-associated changes in saliva composition of head and neck cancer patients: A systematic review
Radiother Oncol. 2024 Apr 20:110279. doi: 10.1016/j.radonc.2024.110279. Online ahead of print.ABSTRACTXerostomia is a common radiation-associated toxicity in patients with head and neck cancer. Although several studies examined the decrease in saliva production due to radiotherapy (RT) and investigated the factors associated with this side effect, little is known about the change in radiation-associated saliva composition. This systematic review is the first to summarize existing data and give an overview of the change in pH/buffer capacity, electrolytes, proteins, enzymes, and mucins due to radiation to the salivary gland...
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 22, 2024 Category: Radiology Authors: Michal Staruch Marlene M Speth Peter Neyer Oliver Riesterer Daniel M Aebersold Sonja Stieb Source Type: research

Systematic review of the efficacy of stereotactic ablative radiotherapy for oligoprogressive disease in metastatic cancer
CONCLUSIONS: SABR appears to have clinical benefit in oligoprogresssive prostate, lung, and renal patients. However, the optimal management of patients with oligoprogressive disease is still somewhat uncertain due to lack of prospective data. This will hopefully become clearer in the near future with the publication of further randomised trials.PMID:38648995 | DOI:10.1016/j.radonc.2024.110288 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 22, 2024 Category: Radiology Authors: Emma Doyle Angus J Killean Stephen Harrow Iain D Phillips Source Type: research