Calcifying fibrous tumour of the pleura without gross calcification
We report a rare case that enhancing pleural thickening, confirmed as CFTP through pathological examination, despite the absence of visible calcification on radiological imaging. Key messageCalcifying fibrous tumours of the pleura (CFTP) typically appear as calcified, non-enhancing lesions on chest CT scans. However, enhancing pleural lesions can mimic malignancy like mesothelioma. We report a rare case that enhancing pleural thickening, confirmed as CFTP through pathological examination, despite the absence of visible calcification on radiological imaging. (Source: Respirology Case Reports)
Source: Respirology Case Reports - May 2, 2024 Category: Respiratory Medicine Authors: Hwan Jin Lee, Jae Seok Jeong, Yong Chul Lee Tags: CLINICAL IMAGE Source Type: research

A case of pulmonary primary MALT lymphoma with distinctive bronchoscopic findings
This article is a case of pulmonary primary MALT lymphoma with characteristic bronchoscopy findings. Immunochemical staining of IRTA-1 was especially useful for diagnosis. AbstractMucosa-associated lymphoid tissue (MALT) is a low-grade lymphoma, but cases in which it has transformed into a high-grade lymphoma have been reported, necessitating an accurate diagnosis. The patient was a 79-year-old nonsmoking Japanese female with history of ocular sarcoidosis. A computed tomography scan of her chest revealed a 35-mm nodule in the left S1  + 2, contiguous with the lymph nodes. Additional nodules were observed around the lef...
Source: Respirology Case Reports - May 1, 2024 Category: Respiratory Medicine Authors: Hiroyuki Miura, Jun Miura, Shinichi Goto, Tomoko Yamamoto Tags: CASE REPORT Source Type: research

Tracheobronchomalacia following allogeneic haematopoietic stem cell transplantation
We present two patients who developed tracheobronchomalacia (TBM) following allogeneic haematopoietic stem cell transplantation (HSCT) and were initially treated for post-transplant bronchiolitis obliterans syndrome (BOS) but did not experience symptom improvement. However, after treatment with continuous positive airway pressure, their symptom subsided. AbstractTracheobronchomalacia (TBM) occurs due to the weakening of cartilaginous part of the trachea, resulting in compromised airway function and leading to symptoms such as dyspnea, cough, and inability to clear secretions. Bronchiolitis obliterans syndrome (BOS) is the ...
Source: Respirology Case Reports - May 1, 2024 Category: Respiratory Medicine Authors: Pitirat Panpruang, Dararat Eksombatchai, Viboon Boonsarngsuk Tags: CASE REPORT Source Type: research

Recommencement of atezolizumab with associated pulmonary sarcoid ‐like reaction
An 81  year old male with Child-Pugh A cirrhosis and metastatic hepatocellular carcinoma (HCC) treated with 3-weekly atezolizumab and bevacizumab developed a pulmonary sarcoid-like reaction (SLR) after 5 months. Atezolizumab was identified as the likely culprit. He was treated with prednisolone, resul ting in improvement, and was successfully rechallenged with both atezolizumab and bevacizumab. AbstractAn 81  year old male with Child-Pugh A cirrhosis and metastatic hepatocellular carcinoma (HCC) treated with 3-weekly atezolizumab and bevacizumab developed a pulmonary sarcoid-like reaction (SLR) after 5 months. Atez...
Source: Respirology Case Reports - April 27, 2024 Category: Respiratory Medicine Authors: Khai Tam, Michael Wallace, Siobhain Mulrennan Tags: CASE REPORT Source Type: research

An example of ventilatory limitation during cardiopulmonary exercise testing in a patient with COPD
A 64-year-old gentleman with obesity and moderate COPD attended for further evaluation of ongoing dyspnoea despite treatment with dual long acting bronchodilators. A cardiopulmonary exercise test (CPET) was performed, which demonstrated reduced peak work and oxygen consumption with evidence of dynamic hyperinflation, abnormal gas exchange and ventilatory limitation despite cardiac reserve. The CPET clarified the physiological process underpinning the patient's dyspnoea and limiting the patient's activities. This, in turn, helped the clinician tailor the patient's management plan. AbstractA 64-year-old obese gentleman atten...
Source: Respirology Case Reports - April 26, 2024 Category: Respiratory Medicine Authors: Claude S. Farah, Leigh M. Seccombe, Greg G. King, David G. Chapman, Charles G. Irvin Tags: CASE REPORT Source Type: research

Neoadjuvant nivolumab plus chemotherapy followed by resection for superior sulcus tumour with high PD ‐L1 expression: A case report
This report represents a new treatment option for superior sulcus tumours. (Source: Respirology Case Reports)
Source: Respirology Case Reports - April 26, 2024 Category: Respiratory Medicine Authors: Takahito Nakaya, Yoshimitsu Hirai, Hiroaki Akamatsu, Fumiyoshi Kojima, Hideto Iguchi, Aya Fusamoto, Yumi Yata, Takahiro Nagai, Daiki Kitahara, Toshiaki Takakura, Yoshiharu Nishimura, Nobuyuki Yamamoto Tags: CASE REPORT Source Type: research

Issue Information
(Source: Respirology Case Reports)
Source: Respirology Case Reports - April 26, 2024 Category: Respiratory Medicine Tags: ISSUE INFORMATION Source Type: research

Lemborexant ‐induced interstitial lung disease: A case report
We report the first case of drug-induced interstitial lung disease attributed to lemborexant. AbstractWe report the first case of drug-induced interstitial lung disease attributed to lemborexant. A 66-year-old man reported to our hospital with the acute onset of cough and breathlessness with ground-glass opacity on radiological examination. Symptoms were identified after taking lemborexant for 2 consecutive days. The patient had undergone lemborexant treatment 2  years prior and had exhibited no symptoms at that time. The drug-induced lymphocyte stimulation test for lemborexant was positive. He showed rapid improvement u...
Source: Respirology Case Reports - April 26, 2024 Category: Respiratory Medicine Authors: Satoshi Nakahara, Yumiko Ishii, Reika Egashira, Kazuya Tsubouchi, Mikihiro Kohno, Tomoyoshi Takenaka, Kentaro Tanaka, Isamu Okamoto Tags: CASE REPORT Source Type: research

Respiratory maze: An anatomical variant of tracheal bronchus
Tracheal bronchus is a rare congenital abnormality of bronchial variation arising from trachea. Special attention should be paid during intubation as it can potentially obstruct the bronchus. Key messageThis case highlights an uncommon anatomical variation in the airway known as Tracheal bronchus, which can sometimes lead to recurrent pneumonia. It is crucial to exercise caution during intubation in patients with this condition. (Source: Respirology Case Reports)
Source: Respirology Case Reports - April 25, 2024 Category: Respiratory Medicine Authors: Dedeepya Gullapalli, Shivendra Tangutoori, Subramanya Shyam Ganti Tags: CLINICAL IMAGE Source Type: research

Arthrogryposis multiplex congenita causing hypercapnic respiratory failure and airway obstruction in an adult patient
This case highlights arthrogryposis multiplex congenita (AMC) as a rare cause of hypercapnoeic respiratory failure and airway obstruction in adults and emphasizes the usage of leak-port in tracheostomy-NIV (non-invasive-ventilation) specially in resource poor setting when the tracheostomy-NIV mask is unavailable. Key messageThis case highlights arthrogryposis multiplex congenita (AMC) as a rare cause of hypercapnoeic respiratory failure and airway obstruction in adults and emphasizes the usage of leak-port in tracheostomy-NIV (non-invasive-ventilation) specially in resource poor setting when the tracheostomy-NIV mask is un...
Source: Respirology Case Reports - April 24, 2024 Category: Respiratory Medicine Authors: Harshana Bandara, Sathiaruban Sathiyamoorthy, Dinusha Withana, Tharindi Dissanayake, Harshani Athapaththu, Wathsala Gunasinghe Tags: CLINICAL IMAGE Source Type: research

A challenging case of drug ‐related acute fibrinous and organizing pneumonia: A rare case report
We present a case of AFOP probably induced by anti-prostate cancer medications. AbstractA 65-year-old man presented with intermittent fever and progressive shortness of breath. He responded poorly to antibiotics and corticosteroids (methylprednisolone 40  mg/d). Chest computed tomography scans showed diffuse consolidations and ground glass density patchy opacities in both lungs and these lesions progressed rapidly. The diagnosis of acute fibrinous and organizing pneumonia (AFOP) was confirmed through transbronchial cryobiopsy. This patient had pro state cancer with bone metastasis for 4 months and took the anti-prostat...
Source: Respirology Case Reports - April 24, 2024 Category: Respiratory Medicine Authors: Chenxia Guo, Wei Wu, Xiang Zhu, Qingtao Zhou, Ying Liang Tags: CASE REPORT Source Type: research

Pulmonary artery pseudoaneurysm after thoracic radiation therapy: A case report and review of the literature
We describe a 72-year-old patient, with a past medical history of a lung carcinoma for which she was treated with chemoradiotherapy 6  years prior, who presented with hemoptysis. She was hemodynamically stable and there were no other complaints. CT angiography of the thorax showed a PAP originating from a branch of the right pulmonary artery in the previously irradiated area. The patient was successfully treated by an embolizati on with plugs. Treatment of lung carcinoma with chemoradiotherapy can result in the development of a PAP. Clinicians should be aware of this complication, even years after the therapy. In literat...
Source: Respirology Case Reports - April 24, 2024 Category: Respiratory Medicine Authors: Gerdinique (G. C.) Maessen, Thijs ( T. W.) Hoffman, Lidwien ( L.) Graat ‐Verboom, Marc ( M.) van Leersum, Hans‐Jurgen ( J. J.) Mager Tags: CASE REPORT Source Type: research

Achieving complete metabolic response in stage IV lung adenocarcinoma with chemotherapy, nivolumab, ipilimumab, and salvage SBRT: A case report
A 55-year-old male with stage IV oncogene-negative, PDL1-negative lung adenocarcinoma demonstrated a complete metabolic response to a novel treatment strategy. This regimen combined double immune checkpoint inhibition (ICI) with chemotherapy, followed by stereotactic body radiotherapy (SBRT), after initial partial response to two cycles of carboplatin, pemetrexed, nivolumab, and ipilimumab, plus maintenance with nivolumab and ipilimumab. This case underscores the effectiveness of integrating multiple treatment modalities for non-small cell lung cancer (NSCLC). AbstractOncogene-negative, PDL1-negative metastatic non-small c...
Source: Respirology Case Reports - April 24, 2024 Category: Respiratory Medicine Authors: Salvador Gamez Casado, Javier David Benitez Fuentes, Beatriz Álvarez Rodríguez, Gema García Ledo Tags: CASE REPORT Source Type: research

Successful ultrathin bronchoscopy with cryobiopsy for diagnosing and removing mucus plugs in allergic bronchopulmonary mycosis mimicking lung cancer
We present a case of successful ultrathin bronchoscopy with cryobiopsy for diagnosing and removing mucus plugs in a patient with allergic bronchopulmonary mycosis mimicking lung cancer. Key messageIn patients presenting with abnormal pulmonary nodules, especially those with a history of asthma, allergic bronchopulmonary mycosis should be considered. Eosinophil counts and IgE levels should be checked in such patients. (Source: Respirology Case Reports)
Source: Respirology Case Reports - April 24, 2024 Category: Respiratory Medicine Authors: Yuki Takigawa, Hiromi Watanabe, Ken Sato, Mayu Goda, Tomoyoshi Inoue, Miho Fujiwara, Suzuka Matsuoka, Kenichiro Kudo, Akiko Sato, Keiichi Fujiwara, Takuo Shibayama Tags: CLINICAL IMAGE Source Type: research

Acute myocardial infarction with e ‐cigarette or vaping‐use associated lung injury in a young Filipino vape user
We present a 22-year-old Filipino male with sudden chest pain. He had no known comorbidities but had a two-year history of daily vape use. Work-up revealed elevated cardiac markers, anteroseptal ST-elevation myocardial infarction, hypokinesia of the anterior wall and interventricular septum, and an ejection fraction of 30%. Chest radiography showed consolidation pneumonia but culture studies and Biofire Pneumonia Panel were negative for microbial detection. Coronary angiography revealed chronic total obstruction of the mid-left anterior descending (LAD) and right coronary arteries (RCA). Percutaneous coronary angioplasty o...
Source: Respirology Case Reports - April 18, 2024 Category: Respiratory Medicine Authors: Margarita Isabel C. Fernandez, Margaret Francine Co, Janine Bianca Marie Rafael, Regiel Christian Mag ‐usara, Vanessa Ediza, Rafael Luis Gavino, Jan Christian Feliciano, Nigel Jeronimo Santos, Mark Andrian Yano, Julian Alexander Huibonhoa, Ric Tags: CASE REPORT Source Type: research