Bystander cardiopulmonary resuscitation differences by sex – the role of arrest recognition
Out-of-hospital cardiac arrest (OHCA) is associated with poor survival [1,2,3]. Bystander response, including cardiopulmonary resuscitation (CPR) and the use of an automated external defibrillator (AED), is associated with greater survival and better neurological outcomes [4,5,6]. However, the provision of bystander CPR varies by physical, social, and attitudinal factors related to the bystander and patient [7,8]. There is also emerging evidence that bystander response may differ depending on the patient ’s sex [9,10,11]. (Source: Resuscitation)
Source: Resuscitation - April 27, 2024 Category: Emergency Medicine Authors: Sonali Munot, Janet E Bray, Julie Redfern, Adrian Bauman, Simone Marschner, Christopher Semsarian, Alan Robert Denniss, Andrew Coggins, Paul M Middleton, Garry Jennings, Blake Angell, Saurabh Kumar, Pramesh Kovoor, Matthew Vukasovic, Jason C Bendall, T Ev Tags: Clinical paper Source Type: research

Return to work after out of hospital cardiac arrest, insights from a prospective multicentric french cohort
The objective of this study was to assess components of return to work among OHCA survivors. (Source: Resuscitation)
Source: Resuscitation - April 27, 2024 Category: Emergency Medicine Authors: Nolwen Flajoliet, Jeremy Bourenne, Nathalie Marin, Jonathan Chelly, Jean Baptiste Lascarrou, C édric Daubin, Wulfran Bougouin, Alain Cariou, Guillaume Geri Tags: Clinical paper Source Type: research

Clinicians ’ approach to predicting post-cardiac arrest outcomes for patients enrolled in a United States clinical trial
Perceived poor prognosis can lead to withdrawal of life-sustaining therapies (WLST) in patients who might otherwise recover. We characterized clinicians ’ approach to post-arrest prognostication in a multicenter clinical trial. (Source: Resuscitation)
Source: Resuscitation - April 27, 2024 Category: Emergency Medicine Authors: Alexis Steinberg, Yanran Yang, Baruch Fischhoff, Clifton W. Callaway, Patrick Coppler, Romergryko Geocadin, Robert Silbergleit, William J. Meurer, Ramesh Ramakrishnan, Sharon D. Yeatts, Jonathan Elmer Tags: Clinical paper Source Type: research

Personalized Resuscitation Using 3D Transesophageal Echocardiography
To the Editor- (Source: Resuscitation)
Source: Resuscitation - April 23, 2024 Category: Emergency Medicine Authors: Chia-Ching Chen, Diane Lee, Hung-Tsang Yen, Wan-Ching Lien Tags: Letter to the Editor Source Type: research

The association of recent simulation training and clinical experience of team leaders with cardiopulmonary resuscitation quality during in-hospital cardiac arrest
We aimed to investigate the association of recent team leader simulation training ( (Source: Resuscitation)
Source: Resuscitation - April 19, 2024 Category: Emergency Medicine Authors: Johannes Wittig, Bo L øfgren, Rasmus P Nielsen, Rikke Højbjerg, Kristian Krogh, Hans Kirkegaard, Robert A. Berg, Vinay M. Nadkarni, Kasper G Lauridsen Tags: Clinical paper Source Type: research

Evaluating the impact of ELSO guideline adherence on favorable neurological outcomes among patients requiring extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest
Selecting the appropriate candidates for extracorporeal cardiopulmonary resuscitation (ECPR) for out-of-hospital cardiac arrest (OHCA) is challenging. Previously, the Extracorporeal Life Support Organization (ELSO) guidelines suggested the example of inclusion criteria. However, it is unclear whether patients who meet the inclusion criteria of the ELSO guidelines have more favorable outcomes. We aimed to evaluate the relationship between the outcomes and select inclusion criteria of the ELSO guidelines. (Source: Resuscitation)
Source: Resuscitation - April 19, 2024 Category: Emergency Medicine Authors: Akira Kawauchi, Yohei Okada, Makoto Aoki, Tomoko Ogasawara, Takashi Tagami, Nobuya Kitamura, Mitsunobu Nakamura, behalf of the SOS-KANTO 2017 Study Group Tags: Clinical paper Source Type: research

Biomarkers for Neuroprognostication after Standard versus Extracorporeal Cardiopulmonary Resuscitation – A Sub-analysis of Prague-OHCA Study
Limited evidence exists for prognostic performance of biomarkers in patients resuscitated from out-of-hospital cardiac arrest (OHCA) with extracorporeal CPR (ECPR). We hypothesized that (1) the time course and (2) prognostic performance of biomarkers might differ between CPR and ECPR in a sub-analysis of Prague-OHCA study. (Source: Resuscitation)
Source: Resuscitation - April 19, 2024 Category: Emergency Medicine Authors: Helena Brodska, Jana Smalcova, Petra Kavalkova, Danielle R. Lavage, Milan Dusik, Jan Belohlavek, Tomas Drabek Tags: Clinical paper Source Type: research

Cerebral Edema Following Cardiac Arrest: Are All Shades of Gray Equal?
The annual incidence of in-hospital cardiac arrest (IHCA) in the United States is increasing and approaching the burden of out-of-hospital cardiac arrest (OHCA) [1]. Guidelines for treatment and prognostication are often extrapolated from OHCA, however, IHCA is a distinct disease subtype that requires separate investigation [2 –4] . The recent publication of Ten Steps Toward Improving In-Hospital Cardiac Arrest Quality of Care and Outcomes highlights the importance of having systems of care focused on unique considerations for IHCA [5]. (Source: Resuscitation)
Source: Resuscitation - April 16, 2024 Category: Emergency Medicine Authors: Rachel Beekman, Emily J. Gilmore Tags: Editorial Source Type: research

CT Brain Perfusion Patterns and Clinical Outcome after Successful Cardiopulmonary Resuscitation: A Pilot Study
Cardiac arrest is a significant global health issue with an incidence rate of 38 –55 per 100,000 person-years [1]. Re-establishing the spontaneous circulation with restoration of the cerebral blood flow (CBF) to the ischaemic brain tissues can induce secondary brain injury and tissue inflammatory response, a condition known as post-cardiac-arrest brain injury (PCABI). PCABI ca uses changes in the cerebral perfusion [2], contributing significantly to mortality and morbidity following cardiac arrest. (Source: Resuscitation)
Source: Resuscitation - April 14, 2024 Category: Emergency Medicine Authors: Arsany Hakim, Mattia Branca, Christoph Kurmann, Benedikt Wagner, Manuela Iten, Matthias H änggi, Franca Wagner Tags: Clinical paper Source Type: research

Cardiac arrest: Treatment is Prevention?
The management of cardiac arrest has benefited from recent advances in cardiopulmonary resuscitation techniques. However, despite improvements, the incidence of sudden cardiac death is still high, with more than 4.1 deaths per 100,000 person-years in the United States, and continues to have very low survival rates at hospital discharge - 8% on average - ranging from 0% to 18% [1 –3]. In response to this issue, research and interventions on cardiac arrest prevention has been greatly developed. As early as 2005, the International Liaison Committee on Resuscitation included prevention of out-of-hospital cardiac arrest as th...
Source: Resuscitation - April 11, 2024 Category: Emergency Medicine Authors: Alexis Descatha, Dominique Savary Tags: Editorial Source Type: research

Recalled Experience of Death: Disinhibition not Degeneration in Relation to Death Facilitates Inner States of Lucid Hyperconsciousness with Novel Cognitive Insights
To the Editor, (Source: Resuscitation)
Source: Resuscitation - April 10, 2024 Category: Emergency Medicine Authors: Sam Parnia, Jignesh Patel, Benjamin M. Bloom, Erik Kulstad, Charles D. Deakin, Rebecca Spiegel Tags: Reply to Correspondence Source Type: research

Alternative defibrillation strategies: more answers and more questions
Approximately one-quarter of out-of-hospital cardiac arrests (OHCA) treated by emergency medical services (EMS) have an initial ventricular fibrillation (VF) or pulseless ventricular tachycardia.1 –3 While these patients have better outcomes compared to patients with non-shockable rhythms, about half do not respond to multiple defibrillation attempts and remains in VF, decreasing their likelihood of successful resuscitation and favourable outcomes.4–6 (Source: Resuscitation)
Source: Resuscitation - April 10, 2024 Category: Emergency Medicine Authors: Tommaso Scquizzato, Markus B Skrifvars Tags: Editorial Source Type: research

Organ donation after extracorporeal cardiopulmonary resuscitation for refractory out-of-hospital cardiac arrest in a metropolitan cardiac arrest centre in Milan, Italy
Extracorporeal cardiopulmonary resuscitation (ECPR) may improve survival in refractory out-of-hospital cardiac arrest (OHCA) but also expand the donor pool as these patients often become eligible for organ donation. Our aim is to describe the impact of organ donation in OHCA patients treated with ECPR in a high-volume cardiac arrest centre. (Source: Resuscitation)
Source: Resuscitation - April 10, 2024 Category: Emergency Medicine Authors: Matteo Aldo Bonizzoni, Tommaso Scquizzato, Marina Pieri, Silvia Delrio, Pasquale Nardelli, Alessandro Ortalda, Antonio Dell'Acqua, Anna Mara Scandroglio, ECPR-CARE Collaborators Tags: Clinical paper Source Type: research

Norepinephrine or just more epinephrine: which is the best vasopressor for post-arrest shock?
Shock is common after cardiac arrest, affecting up to two-thirds of patients.1,2 The pathophysiology of post-arrest shock is complex. Approximately half of out-of-hospital cardiac arrest (OHCA) patients have post-resuscitation myocardial dysfunction, and distributive shock is common due to systemic inflammation and reperfusion injury.2 –5 Vasopressors, the mainstay of treatment for post-arrest shock, are one of the most common interventions delivered to patients cardiac arrest, but the optimal agent remains unknown. (Source: Resuscitation)
Source: Resuscitation - April 10, 2024 Category: Emergency Medicine Authors: Nicholas J. Johnson, Ari Moskowitz Tags: Editorial Source Type: research

Recognizing the fastest growing cause of out-of-hospital cardiac arrest
Deaths due to opioid overdose have increased steadily in the past two decades with an incidence of 25 per 100,000 population in 2021. [1] Opioid toxicity, particularly from synthetic opioids other than methadone, accounts for over 75% of these deaths, with a peak incidence between 35-44 years of age.[1] Death due to opioid toxicity therefore approximates one third the incidence of emergency medical service (EMS) treated out-of-hospital cardiac arrest (OHCA) based on the 2019 Cardiac Arrest Registry to Enhance Survival (CARES) data. (Source: Resuscitation)
Source: Resuscitation - April 9, 2024 Category: Emergency Medicine Authors: Aaron M. Orkin, Cameron Dezfulian Tags: Editorial Source Type: research