CDK4/6 activity is required during G2 arrest to prevent stress-induced endoreplication | Science
Cell cycle events are coordinated by cyclin-dependent kinases (CDKs) to ensure robust cell division. CDK4/6 and CDK2 regulate the growth 1 (G1) to synthesis (S) phase transition of the cell cycle by responding to mitogen signaling, promoting E2F ... (Source: Science: Current Issue)
Source: Science: Current Issue - May 2, 2024 Category: Science Source Type: research

Induction of social contagion for diverse outcomes in structured experiments in isolated villages | Science
Certain people occupy topological positions within social networks that enhance their effectiveness at inducing spillovers. We mapped face-to-face networks among 24,702 people in 176 isolated villages in Honduras and randomly assigned villages to ... (Source: Science: Current Issue)
Source: Science: Current Issue - May 2, 2024 Category: Science Source Type: research

A single cell atlas of sexual development in Plasmodium falciparum | Science
The developmental decision made by malaria parasites to become sexual underlies all malaria transmission. Here, we describe a rich atlas of short- and long-read single-cell transcriptomes of over 37,000 Plasmodium falciparum cells across ... (Source: Science: Current Issue)
Source: Science: Current Issue - May 2, 2024 Category: Science Source Type: research

A blueprint for tumor-infiltrating B cells across human cancers | Science
B lymphocytes are essential mediators of humoral immunity and play multiple roles in human cancer. To decode the functions of tumor-infiltrating B cells, we generated a B cell blueprint encompassing single-cell transcriptome, B cell –receptor repertoire, ... (Source: Science: Current Issue)
Source: Science: Current Issue - May 2, 2024 Category: Science Source Type: research

News at a glance | Science
HomeScienceVol. 384, No. 6695News at a glanceBack To Vol. 384, No. 6695 Full accessIn Brief Share on News at a glanceScience2 May 2024Vol 384, Issue 6695pp. 490-492 PREVIOUS ARTICLEA pandemic agreement is within reachPreviousNEXT ARTICLEBird flu appears entrenched in U.S. dairy herdsNext ContentsHighest scope opens its infrared eyesAll dog noses are created equalAustralia museum staff get a rep … (Source: Science: Current Issue)
Source: Science: Current Issue - May 2, 2024 Category: Science Source Type: research

A fellow engineer and presidential rival | Science
HomeScienceVol. 384, No. 6695A fellow engineer and presidential rivalBack To Vol. 384, No. 6695 Full accessFeature Share on A fellow engineer and presidential rivalRodrigo P érez OrtegaAuthors Info& AffiliationsScience2 May 2024Vol 384, Issue 6695p. 504 PREVIOUS ARTICLEA scientist for presidentPreviousNEXT ARTICLEConductive hydrogels put electrons in chargeNext ContentsInformation& AuthorsMetr … (Source: Science: Current Issue)
Source: Science: Current Issue - May 2, 2024 Category: Science Source Type: research

Unsettled science on longer-run effects of early education | Science
More rigorous research is needed on how to design programs (Source: Science: Current Issue)
Source: Science: Current Issue - May 2, 2024 Category: Science Source Type: research

Conductive hydrogels put electrons in charge | Science
Semiconductor hydrogels enable active bioelectronics (Source: Science: Current Issue)
Source: Science: Current Issue - May 2, 2024 Category: Science Source Type: research

B cell trajectories influence cancer outcomes | Science
Two types of B cell in the tumor microenvironment modulate antitumor immunity (Source: Science: Current Issue)
Source: Science: Current Issue - May 2, 2024 Category: Science Source Type: research

A reverse brake for the cell cycle | Science
Mitogenic signaling acts beyond S-phase entry to prevent whole-genome duplications (Source: Science: Current Issue)
Source: Science: Current Issue - May 2, 2024 Category: Science Source Type: research

Zombie malaria parasites | Science
Natural infections are distinct from those of laboratory —or zombie—strains (Source: Science: Current Issue)
Source: Science: Current Issue - May 2, 2024 Category: Science Source Type: research

Daniel Kahneman (1934 –2024) | Science
Pioneer in the psychology of judgment and decision-making (Source: Science: Current Issue)
Source: Science: Current Issue - May 2, 2024 Category: Science Source Type: research

Darwin meets Dickinson | Science
The biologist and the poet shared deep sensibilities about the natural world (Source: Science: Current Issue)
Source: Science: Current Issue - May 2, 2024 Category: Science Source Type: research

Pandemics and their accelerants | Science
A well-researched account of the factors that drive pandemics misses an opportunity to indict broader social systems (Source: Science: Current Issue)
Source: Science: Current Issue - May 2, 2024 Category: Science Source Type: research

Groundwater flooding risks overlooked | Science
HomeScienceVol. 384, No. 6695Groundwater flooding risks overlookedBack To Vol. 384, No. 6695 Full accessLetter Share on Groundwater flooding risks overlookedHamid M. Behzad and Yunpeng Nie [email  protected]Authors Info& AffiliationsScience2 May 2024Vol 384, Issue 6695pp. 518-519 PREVIOUS ARTICLEPandemics and their accelerantsPreviousNEXT ARTICLENextgen Voices: Preventing Bad BehaviorNext Conte … (Source: Science: Current Issue)
Source: Science: Current Issue - May 2, 2024 Category: Science Source Type: research