Southern African Journal of HIV Medicine This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Effect of dolutegravir on ferritin, iron, and C-reactive protein among people living with HIV and co-infections
Conclusion: The presence of co-infections in PLWH is associated with higher VL and with chronic inflammation. Ferritin and CRP decreased on dolutegravir-based ART but remained higher in people with co-infections despite similar rates of virologic suppression. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - April 30, 2024 Category: African Health Authors: Bridget Kamurai Source Type: research

Southern African HIV Clinicians Society Guideline for the clinical management of syphilis
Syphilis, ‘the great imitator’, caused byTreponema pallidum infection, remains a complex and multifaceted disease with a rich history of clinical diversity. This guideline aims to be a comprehensive guide for healthcare workers in Southern Africa, offering practical insights into the epidemiology, pathogenesis, clinical manifestations, diagnostic testing, therapeutic principles, and public health responses to syphilis. Although the syphilis burden has declined over the years, recent data indicate a troubling resurgence, particularly among pregnant women and neonates. This guideline highlights the diagnostic challenges ...
Source: Southern African Journal of HIV Medicine - April 30, 2024 Category: African Health Authors: Remco P.H. Peters Source Type: research

Virologic outcomes with tenofovir-lamivudine-dolutegravir in adults failing PI-based second-line ART
Conclusion: Amongst patients failing second-line PI with no PI resistance, switching to TLD was associated with higher virologic suppression, likely due to improved adherence. Virologic outcomes were similar in patients with PI resistance switched to darunavir-based regimens or TLD. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - April 26, 2024 Category: African Health Authors: Ying Zhao Source Type: research

Trends in body mass index in the pre-dolutegravir period in South Africa
Conclusion: The increase in BMI in PLWH and HIV-negative participants is a serious warning signal as obesity results in morbidity and mortality. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - April 23, 2024 Category: African Health Authors: Florian van Ginkel Source Type: research

Management of drug-induced liver injury in people with HIV treated for tuberculosis: 2024 update
No abstract available. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - March 30, 2024 Category: African Health Authors: Tom Boyles Source Type: research

Inflammatory mechanisms contributing to retinal alterations in HIV infection and long-term ART
People living with HIV (PLWH) may face an increased risk of eye complications associated with ageing, chronic inflammation, and the toxicity arising from long-term antiretroviral therapy (ART). This review aims to understand how inflammatory pathways contribute to retinal alterations observed in PLWH on long-term ART. This review was conducted using four electronic database searches, namely Scopus, Hinari, Google Scholar, and PubMed; from 1996 (when ART became available) until January 2022, without language restriction. Sources from clinical trials, meta-analyses, randomised controlled trials, and systematic reviews were u...
Source: Southern African Journal of HIV Medicine - March 26, 2024 Category: African Health Authors: Lungile M. Buthelezi Source Type: research

Effects of the COVID-19 pandemic on early infant diagnosis of HIV in Cape Town, South Africa
Conclusion: Vertical transmission of HIV at 10 weeks increased in the Cape Town Metropolitan during the initial COVID-19 lockdown. There was also an increase in the proportion of deaths without testing by 10 weeks in the 2020 group. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - March 18, 2024 Category: African Health Authors: Hendrike van Vollenhoven Source Type: research

Retrospective review of maternal HIV viral load electronic gatekeeping codes in South Africa
Conclusion: Although overall national uptake of maternal HIV VL eGK codes was low, antenatal and delivery uptake improved over time, thereby facilitating use of eGK codes for programmatic monitoring of maternal VLS rates for the first time. Quality of care among pregnant AGYW requires urgent attention. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - February 20, 2024 Category: African Health Authors: Siphesihle K. Mahanjana Source Type: research

Very low HIV positivity on paediatric surgical wards in Mozambique: Implications for inpatient provider-initiated testing programmes
No abstract available. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - January 8, 2024 Category: African Health Authors: Henriques Viola Source Type: research

Outcomes and characteristics of patients on protease inhibitors at a tertiary level antiretroviral clinic
Conclusion: PIs have long been a cornerstone of second-line ART. This study demonstrates the real-world utility of PIs, as well as their disadvantages. There was no difference in the outcomes of patients who received recycled NRTIs in second-line regimens. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - December 21, 2023 Category: African Health Authors: Michele Perks Source Type: research

Country ownership and sustainable programming of the HIV response in South Africa: A scoping review
Conclusion: South Africa appears to be progressing well along the spectrum of country ownership, but sustained efforts are required to combat HIV. Greater ownership over KP programming and prevention services are especially needed to achieve greater impact. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - November 30, 2023 Category: African Health Authors: Refilwe N. Phaswana-Mafuya Source Type: research

Dolutegravir resistance in three pregnant and breastfeeding women in South Africa
No abstract available. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - November 28, 2023 Category: African Health Authors: Ninke Fourie Source Type: research

Acknowledgement to Reviewers
No abstract available. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - November 16, 2023 Category: African Health Authors: Editoial Office Source Type: research

Confronting the human papillomavirus –HIV intersection: Cervical cytology implications for Kenyan women living with HIV
Conclusion: Among WLHIV at KNH, abnormal cytology was common and more frequent among women with multiple HR-HPV infections. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - October 27, 2023 Category: African Health Authors: James M. Kangethe Source Type: research

Thrombotic thrombocytopaenic purpura in the era of HIV: A single-centre experience
Conclusion: HIV is an important cause of TTP in the local context. Haematological and neurological involvement are more severe in HIV-associated TTP. Acceptable survival rates are achievable with PEX even in advanced HIV infection; renal sequalae are less common in this group. (Source: Southern African Journal of HIV Medicine)
Source: Southern African Journal of HIV Medicine - October 27, 2023 Category: African Health Authors: Yusuf Moola Source Type: research