Managing hepatocellular carcinoma across the stages: efficacy and outcomes of stereotactic body radiotherapy
ConclusionSBRT offers a  compelling option for achieving high local control and promising survival outcomes in HCC. The study supports a radiation dose range of 61–73.1 Gy, coupled with a mean liver dose under 12.6–12.8 Gy as EQD2, to achieve favorable FFLP rates, with acceptable toxicity rates. (Source: Strahlentherapie und Onkologie)
Source: Strahlentherapie und Onkologie - April 30, 2024 Category: Cancer & Oncology Source Type: research

Knowledge and competences in hematological malignancies amongst radiation oncology residents in Germany —results from a national survey
ConclusionThis survey highlights the diversity of resident education regarding hematological malignancies in German radiation oncology programs. Knowledge gaps exist in key areas, including pediatric cases and specialized techniques. Competence-based education, interactive teaching formats, and rotations to specialized centers are potential strategies to address these gaps. The study contributes to the understanding of the federal educational landscape, underscoring the need for standardized and comprehensive training to ensure optimal patient care in hematological malignancies within the context of radiation oncology. Fur...
Source: Strahlentherapie und Onkologie - April 29, 2024 Category: Cancer & Oncology Source Type: research

Potential Single Nucleotide Polymorphisms markers for radiation dermatitis in head and neck cancer patients: a  meta-analysis
ConclusionThe most prevalent SNPs may be predictors of acute RD. The analysis of SNP before starting radiation therapy may be a  promising method to predict the risk of developing radiation dermatitis and allow radiosensitive patients to have a customized treatment. This current review provides new research directions. (Source: Strahlentherapie und Onkologie)
Source: Strahlentherapie und Onkologie - April 26, 2024 Category: Cancer & Oncology Source Type: research

Patient vulnerability in stereotactic arrhythmia radioablation  (STAR): a preliminary ethical appraisal from the STOPSTORM.eu consortium
AbstractThis preliminary ethical appraisal from the STOPSTORM.eu consortium is meant to raise critical points that clinicians administering stereotactic arrhythmia radioablation should consider to meet the highest standards in medical ethics and thus promote quality of life of patients recruited for radiotherapy treatments at a  stage in which they experience a significant degree of vulnerability. (Source: Strahlentherapie und Onkologie)
Source: Strahlentherapie und Onkologie - April 23, 2024 Category: Cancer & Oncology Source Type: research

Dosimetric comparison of advanced radiation techniques for scalp-sparing in low-grade gliomas
ConclusionOur study provides evidence that the SO approach is a  feasible technique for reducing scalp radiation dose. However, it is imperative to conduct prospective trials to assess the benefits associated with this approach. (Source: Strahlentherapie und Onkologie)
Source: Strahlentherapie und Onkologie - April 22, 2024 Category: Cancer & Oncology Source Type: research

5-Jahres-Follow-up der RAPIDO-Studie: Zur ück in die Zukunft der Langzeitradiochemotherapie bei totaler neoadjuvanter Therapie (TNT) des lokal fortgeschrittenen Rektumkarzinoms?
(Source: Strahlentherapie und Onkologie)
Source: Strahlentherapie und Onkologie - April 22, 2024 Category: Cancer & Oncology Source Type: research

Radiotherapie plus Durvalumab beim lokal fortgeschrittenen NSCLC: die DOLPHIN-Studie
(Source: Strahlentherapie und Onkologie)
Source: Strahlentherapie und Onkologie - April 18, 2024 Category: Cancer & Oncology Source Type: research

Advances and residual knowledge gaps in the neck management of head and neck squamous cell carcinoma patients with advanced nodal disease undergoing definitive (chemo)radiotherapy for their primary
ConclusionPersonalized neck management is an increasingly important aspect of the overall therapeutic strategies in cN+ HNSCC.Graphic abstract (Source: Strahlentherapie und Onkologie)
Source: Strahlentherapie und Onkologie - April 10, 2024 Category: Cancer & Oncology Source Type: research

Letter to the Editor: reply to “Comparison of patient setup accuracy for optical surface-guided and X-ray-guided imaging with respect to the impact on intracranial stereotactic radiotherapy”
(Source: Strahlentherapie und Onkologie)
Source: Strahlentherapie und Onkologie - April 5, 2024 Category: Cancer & Oncology Source Type: research

Reply to Letter to the Editor: Reply to comparison of patient setup accuracy for optical surface-guided and X-ray-guided imaging with respect to the impact on intracranial stereotactic radiotherapy
(Source: Strahlentherapie und Onkologie)
Source: Strahlentherapie und Onkologie - April 5, 2024 Category: Cancer & Oncology Source Type: research

Letter to the Editor: reply to “Comparison of patient setup accuracy for optical surface-guided and X-ray-guided imaging with respect to the impact on intracranial stereotactic radiotherapy”
(Source: Strahlentherapie und Onkologie)
Source: Strahlentherapie und Onkologie - April 5, 2024 Category: Cancer & Oncology Source Type: research

Reply to Letter to the Editor: Reply to comparison of patient setup accuracy for optical surface-guided and X-ray-guided imaging with respect to the impact on intracranial stereotactic radiotherapy
(Source: Strahlentherapie und Onkologie)
Source: Strahlentherapie und Onkologie - April 5, 2024 Category: Cancer & Oncology Source Type: research

DEGRO guideline for personalized radiotherapy of brain metastases and leptomeningeal carcinomatosis in patients with breast cancer
Conclusion and recommendationsDespite the fact that the biological subtype of breast cancer influences both the occurrence and relapse patterns of breast cancer brain metastases (BCBM), for most scenarios, no specific recommendations regarding radiotherapy can be made based on the existing evidence. For a  limited number of BCBM (1–4), stereotactic radiosurgery (SRS) or fractionated stereotactic radiotherapy (SRT) is generally recommended irrespective of molecular subtype and concurrent/planned systemic therapy. In patients with 5–10 oligo-brain metastases, these techniques can also be condition ally recommended. For ...
Source: Strahlentherapie und Onkologie - April 1, 2024 Category: Cancer & Oncology Source Type: research