Safety and efficacy of intravenous thrombolysis before mechanical thrombectomy in patients with atrial fibrillation
ConclusionIVT plus EVT leads to better functional outcomes and lower mortality in AIS-LVO patients with AF. Withholding IVT plus EVT from patients with AF alone may not be justified. (Source: Systematic Reviews)
Source: Systematic Reviews - April 30, 2024 Category: International Medicine & Public Health Source Type: research
Prevalence of thyroid dysfunction and associated factors among adult type 2 diabetes mellitus patients, 2000 –2022: a systematic review and meta-analysis
ConclusionThe current systematic review and meta-analysis showed that the TD ’s pooled prevalence was relatively higher than the general population. Therefore, regular screening of TD should be done for T2DM patients. (Source: Systematic Reviews)
Source: Systematic Reviews - April 30, 2024 Category: International Medicine & Public Health Source Type: research
Correction: Patient ‑reported outcome (PRO) instruments used in patients undergoing adoptive cell therapy (ACT) for the treatment of cancer: a systematic review
(Source: Systematic Reviews)
Source: Systematic Reviews - April 30, 2024 Category: International Medicine & Public Health Source Type: research
Epidemiology of hyperglycemia during pregnancy in Ethiopia: prevalence, associated factors, and feto-maternal outcomes: systematic review and meta-analysis
ConclusionAlthough there was some variation between studies, the meta-analysis revealed that approximately seven out of 100 pregnant women in Ethiopia had HIP. A family history of diabetes was found to be a significant predictor of HIP in Ethiopia. Additionally, HIP was associated with various serious adverse outcomes for both mothers and infants in Ethiopia. These findings highlight the need for national guidelines to ensure that pregnant women are uniformly screened for HIP. (Source: Systematic Reviews)
Source: Systematic Reviews - April 29, 2024 Category: International Medicine & Public Health Source Type: research
Psychometric properties of stigma and discrimination measurement tools for persons living with HIV: a systematic review using the COSMIN methodology
ConclusionsThis study recommends three PROMs for different stigma and discrimination scenarios, including IARSS for its good quality and convenience, IHSS for its broader range of items, higher sensitivity, and greater precision, and WHSS for its comprehensive and quick screening. Researchers should also consider the relevance and feasibility of the measurements before putting them into practice.Systematic review registrationPROSPEROCRD42022308579 (Source: Systematic Reviews)
Source: Systematic Reviews - April 27, 2024 Category: International Medicine & Public Health Source Type: research
Impact of the COVID-19 era on preventative primary care for children 0 –5 years old: a scoping review protocol
The objective of this scoping review is to characterise the utilisation of preventative primary care and its association with child development for children ages 0 –5 years old during the COVID-19 era. In addition, we will determine if specific groups of children are at greater risk for reduced access to care.MethodsA systematic search will be conducted for studies published between March 11, 2020, and October 2023 in the following databases: MEDLINE (Ovid), Embase (Ovid), Cochrane Library (CENTRAL and CDSR), Web of Science, and CINAHL (EBSCOhost). This scoping review will follow the methodological framework developed b...
Source: Systematic Reviews - April 26, 2024 Category: International Medicine & Public Health Source Type: research
Comparative benefits and harms of perioperative interventions to prevent chronic pain after orthopedic surgery: a systematic review and network meta-analysis of randomized trials
DiscussionThis network meta-analysis will assess the comparative effectiveness of pharmacological and psychological interventions directed at preventing CPSP after orthopedic surgery. Our findings will inform clinical decision-making and identify promising interventions for future research.Systematic review registrationPROSPERO CRD42023432503. (Source: Systematic Reviews)
Source: Systematic Reviews - April 26, 2024 Category: International Medicine & Public Health Source Type: research
Efficacy of non-instrumental Endodontic treatment in primary teeth: a systematic review of clinical randomized trials
ConclusionNo difference between the NIET technique and the conventional endodontic therapy in primary molars requiring pulpectomy could be confirmed. Results of the present review need to be interpreted with caution since the quality of evidence according to the GRADE was considered as moderate to very low. Therefore, additional clinical trials on the NIET technique are recommended. (Source: Systematic Reviews)
Source: Systematic Reviews - April 25, 2024 Category: International Medicine & Public Health Source Type: research
The usage of population and disease registries as pre-screening tools for clinical trials, a systematic review
Discussion and conclusionThe use of registries for trial pre-screening increases reproducibility of the pre-screening process across trials and sites, allowing for implementation and improvement of a quality assurance process. Pre-screening strategies seem under-reported, and we encourage more trials to use and describe their pre-screening processes, as there is a need for standardized methodological guidelines. (Source: Systematic Reviews)
Source: Systematic Reviews - April 23, 2024 Category: International Medicine & Public Health Source Type: research
Protocol for a systematic review and meta-analysis on Janus kinase inhibitors in the management of vitiligo
DiscussionThe proposed systematic review and meta-analysis describe the methods for summarizing and synthesizing the evidence on the effectiveness and patient-centered outcomes concerning the treatment of vitiligo with JAK inhibitors that were recently approved for this indication. To disseminate further the results of our systematic review, we plan to present them at international conferences and meetings. Our findings will provide robust evidence to facilitate decision-making at the policy or practitioner level.Systematic review registrationPROSPERO CRD42023383920. (Source: Systematic Reviews)
Source: Systematic Reviews - April 19, 2024 Category: International Medicine & Public Health Source Type: research
Efficacy and safety of antibiotics for treatment of leptospirosis: a systematic review and network meta-analysis
ConclusionsFindings recommend that leptospirosis patients be treated with antibiotics, which significantly reduced the leptospirosis defervescence time. Cephalosporins, doxycycline, and penicillin are suggested, and azithromycin may be a suitable alternative for drug-resistant cases.Systematic review registrationPROSPERO CRD42022354938. (Source: Systematic Reviews)
Source: Systematic Reviews - April 16, 2024 Category: International Medicine & Public Health Source Type: research
Protocol for a systematic review and meta-analysis of the prevalence of mental illness among nursing home residents
DiscussionThe study will provide a comprehensive and contemporary account of the prevalence of mental illness among nursing home residents. Meta-analyses will provide robust prevalence estimates across a range of presentations. Key insights will be highlighted, including potential sources of heterogeneity. Implications for residents, researchers, care providers, and policymakers will be noted.Systematic review registrationPROSPERO: CRD42023456226. (Source: Systematic Reviews)
Source: Systematic Reviews - April 16, 2024 Category: International Medicine & Public Health Source Type: research
Natural language processing (NLP) to facilitate abstract review in medical research: the application of BioBERT to exploring the 20-year use of NLP in medical research
ConclusionsBioBERT showed an acceptable performance in the abstract review. If future research shows the high performance of this language model, it can reliably replace manual abstract reviews. (Source: Systematic Reviews)
Source: Systematic Reviews - April 15, 2024 Category: International Medicine & Public Health Source Type: research
Does arthroscopic or open washout in native knee septic arthritis result in superior post-operative function? A systematic review and meta-analysis of randomised controlled trials and observational studies
ConclusionsAW was associated with equivalent to superior post-operative function and lower requirement for further intervention compared with OW. Results need to be interpreted cautiously, taking into consideration the methodological and clinical heterogeneity of the included studies.Systematic review registrationPROSPERO 2022, CRD42022364062. (Source: Systematic Reviews)
Source: Systematic Reviews - April 12, 2024 Category: International Medicine & Public Health Source Type: research
Palliative care needs of people and/or their families with serious and/or chronic health conditions in low- or middle-income country (LMIC) humanitarian settings —a systematic scoping review protocol
DiscussionFindings will be presented in tables and diagrams/charts, followed by a narrative description. The review will run from late October 2022 to early 2023. This is the first systematic scoping review specifically exploring the palliative care needs of patients and/or their family, in LMIC humanitarian settings. The paper from the review findings will be submitted for publication in 2023. (Source: Systematic Reviews)
Source: Systematic Reviews - April 11, 2024 Category: International Medicine & Public Health Source Type: research
