Significant mitral regurgitation after permanent right ventricular pacemaker implantation: prognostic implications
Right ventricular (RV) pacing is the standard of care for pathological bradycardia, with implantation rates of more than 1000 per million population.1, 2 However, despite its symptomatic and survival benefits, left ventricular (LV) adverse remodeling and LV systolic dysfunction have been reported as unwanted effects of chronic RV pacing.2, 3 Furthermore, the development of severe mitral regurgitation (MR) is noted after permanent RV pacemaker (PM) implantation.4, 5 Loss of atrioventricular and interventricular synchrony and transient papillary muscle dysfunction secondary to ischemia caused by fast cardiac pacing, are thou...
Source: The American Journal of Cardiology - May 7, 2024 Category: Cardiology Authors: Takeru Nabeta, Xavier Galloo, Laurens Tops, Jan Stassen, Nina Ajmone Marsan, Pieter van der Bijl, Jeroen J Bax Source Type: research
Valve-in-Valve Transcatheter Aortic Valve Replacement Versus Redo Surgical Aortic Valve Replacement In Patients With Aortic Stenosis: A Systematic Review and Meta-analysis
Aortic stenosis is a common and significant valve condition requiring bioprosthetic heart valves (BHV) with transcatheter aortic valve replacement (TAVR) being strongly recommended for high-risk patients or patients over 75. This meta-analysis aimed to pool existing data on post-procedural clinical as well as echocardiographic outcomes comparing ViV-TAVR to redo-SAVR to assess the short-term and medium-term outcomes for both treatment modalities. A systematic literature search on Cochrane Central, Scopus, and Medline (PubMed interface) electronic databases from inception to August 2023. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - May 7, 2024 Category: Cardiology Authors: Muhammad Moiz Nasir, Armeen Ikram, Muhammad Usman, Jawad Sarwar, Jawad Ahmed, Mohammad Hamza, Syed Ali Farhan, Rabbia Siddiqi, Laila Tul Qadar, Syed Raza Shah, Muhammad Rizwan Khalid, Roha Saeed Memon, Irbaz Hameed Source Type: research
Are sodium-glucose cotransporter-2 inhibitors fantastic for coronary plaque stabilization?
We have read with interest the article by Kurozumi et al about a study conducted in Japan, suggesting the efficacy of sodium-glucose cotransporter-2inhibitors (SGLT2i) on the stabilization of coronary plaques.1 The authors retrospectively investigated serial changes in vulnerable characteristics of non-culprit plaques, including fibrous cap thickness (FCT), by using optical coherence tomography (OCT) at baseline and 6-month follow-up among diabetic patients with acute coronary syndrome (ACS) and compared the changes between patients treated with SGLT2i and those without. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - May 6, 2024 Category: Cardiology Authors: Yoshiyasu Minami, Toshiyuki Iwaya Tags: Readers' comments Source Type: research
Predictors of Disease Progression and Adverse Clinical Outcomes in Patients with Moderate Aortic Stenosis Using an Artificial Intelligence-Based Software Platform
Moderate Aortic Stenosis (AS) patients have a higher risk of adverse clinical outcomes than the general population. How this risk compares to those with severe AS, along with factors associated with outcomes and disease progression, is less clear. We analyzed serial echoes (from 2017-2019) from a single healthcare system using Tempus Next (Chicago, IL) software. AS severity was defined according to American Heart Association/American College of Cardiology (AHA/ACC) guidelines. Outcomes of interest included death or heart failure (HF) hospitalization. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - May 4, 2024 Category: Cardiology Authors: Mahmoud Salem, Hemal Gada, Basel Ramlawi, Miguel Sotelo, Paul Nona, Loren Wagner, Chris Rogers, Logan Brigman, Amit N. Vora Source Type: research
Unveiling the Hidden Danger of Prosthesis Infolding
Since its inception in 2002, transcatheter aortic valve implantation (TAVI) has revolutionized the treatment landscape for symptomatic severe aortic stenosis. Over the years, this minimally invasive procedure has evolved into a cornerstone therapeutic option, catering to a broad spectrum of patients, including those deemed at low surgical risks1,2. The remarkable progress in TAVI technology, coupled with the growing expertise of operators, has propelled this procedure to achieve outcomes comparable with traditional surgical aortic valve replacement. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - May 3, 2024 Category: Cardiology Authors: Giuseppe Tarantini, Francesco Cardaioli Tags: Editorial Source Type: research
Chronic Total Occlusion Percutaneous Coronary Intervention: Mindset, Culture, and Continuous Improvement
The development of complex and higher risk indicated procedures (CHIP) and chronic total occlusion (CTO) percutaneous coronary intervention (PCI) has brought along new challenges in terms of operator training. While the technical aspect of learning CHIP/CTO PCI have been described in detail, very little has been discussed on the mental skills that the operator must possess or develop to be successful.Moreover, an at least equally important piece to CHIP/CTO PCI program development is the professional culture of the institution where these complex procedures are performed, as this can mark the difference between a thriving ...
Source: The American Journal of Cardiology - May 2, 2024 Category: Cardiology Authors: Lorenzo Azzalini, William L. Lombardi Source Type: research
Effect of Left Ventricular Diastolic Dysfunction on the Cardiopulmonary Exercise Test in Patients with Cardiovascular Disease
Left ventricular diastolic dysfunction is one of main pathophysiologies of heart failure with preserved ejection fraction (HFpEF)1. HFpEF is seen in around 50% of heart failure cases, is not related to sex, shows high multiple morbidities and a high proportion of non-cardiovascular death, in addition to cardiovascular death2. The high degree of left ventricular diastolic dysfunction in chronic heart failure has been shown to be associated with a poor prognosis3. Left ventricular diastolic dysfunction is also present in heart failure with reduced ejection fraction (HFrEF)4. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - May 2, 2024 Category: Cardiology Authors: Yuki Inada, Yasunori Suematsu, Takuro Matsuda, Yuiko Yano, Kai Morita, Kakeru Bando, Reiko Teshima, Hiroyuki Fukuda, Kanta Fujimi, Shin-ichiro Miura Source Type: research
Short-term Outcomes of Transcatheter Aortic Valve Replacement in Low-risk Patients with Pure Severe Aortic Regurgitation
This study aimed to explore the feasibility of TAVR treatment in different STS risk patients and to compare the adverse events between the groups. In this study, patients with PSAR who underwent TAVR at Zhongshan Hospital, Fudan University, China, during the inclusion period were included and categorized into three groups based on STS scores. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - May 2, 2024 Category: Cardiology Authors: Lin Da-wei, Weng Zi-long, Fang Yan-xing, Fan Jia-ning, Qi Yi-ming, Zhan Zhi, Long Yu-liang, Pan Wen-zhi, Zhou Da-xin, Ge Jun-bo Source Type: research
Association Between Vegetation Size And Outcome In The POET Trial
Step-down oral antibiotic therapy is associated with a non-inferior long-term outcome compared to continued intravenous antibiotic therapy in the treatment of left-sided infective endocarditis (IE). We aimed to analyze whether step-down oral therapy compared to continued intravenous antibiotic therapy is also associated with a non-inferior outcome in patients with large vegetations (vegetation length ≥ 10 mm) or among patients undergoing surgery before step-down oral therapy. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - May 2, 2024 Category: Cardiology Authors: Rasmus Carter-Storch, Mia Marie Pries-Heje, Jonas A. Povlsen, Ulrik Christensen, Sabine U. Gill, Julie Glud Hjulmand, Niels E. Bruun, Hanne Elming, Trine Madsen, Kurt Fuursted, Martin Schultz, Jens J Christensen, Flemming Rosenvinge, Jannik Helweg-Larsen, Source Type: research
Predictors of Polymorphic Ventricular Tachycardia and Ventricular Fibrillation in Patients with Takotsubo Syndrome
This study aims to identify demographic and clinical factors associated with PVT and VF in patients with TTS. Patients meeting the InterTak criteria for TTS between 2010-2022 were retrospectively identified. The occurrence of PVT/VF with each risk factor was analyzed using logistic regression. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - May 1, 2024 Category: Cardiology Authors: Maroun Chedid, Kevin Buda, Omer Iqbal, Mengistu Simegn, Maroun Chedid, Kevin Buda, Omer Iqbal, Mengistu Simegn Source Type: research
Outcomes After Transcatheter Mitral Valve Intervention: Threatened by Tricuspid Regurgitation
The tricuspid valve (TV) was historically referred to as the forgotten valve and considered to be a passive structure, on the systemic venous side of the heart, without clinically significant function. However, recent studies showed all-cause mortality was higher for tricuspid regurgitation (TR) than for aortic-valve disease or mitral-valve disease (hazard ratios: 2.74, 1.62, 1.25 respectively).1 TR is classified into primary, secondary or implantable device related. Primary tricuspid regurgitation occurs because of intrinsic valve disease and is attributable to congenital anomalies, infective endocarditis, rheumatic disea...
Source: The American Journal of Cardiology - May 1, 2024 Category: Cardiology Authors: Srinivasa Potluri Tags: Editorial Source Type: research
Clinical Outcomes and Resource Utilization in Patients with Peripheral Arterial Disease Hospitalized for Acute Coronary Syndrome
Previous studies have shown an association between acute limb ischemia and higher mortality in patients with Acute Myocardial Infarction. Although Peripheral Artery Disease is a well-known risk factor for development of macrovascular pathology, the effect of its severity is not well investigated in patients hospitalized for Acute Coronary Syndrome (ACS). Using a national cohort of patients with various degrees of Peripheral Arterial Disease, we investigated in-hospital outcomes in patients who were admitted for ACS. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - May 1, 2024 Category: Cardiology Authors: Nameer Ascandar, Joseph Hadaya, Nam Yong Cho, Konmal Ali, Yas Sanaiha, Peyman Benharash Source Type: research
Treating Atrial Fibrillation Is No MAZE: A Reminder To Heart Teams For Concomitant Surgical Ablation For Atrial Fibrillation With Cardiac Surgery
Atrial fibrillation (AF) is the most prevalent arrythmia and is often found during time of other cardiac pathologies which require surgical management including coronary revascularization and valve surgery. Surgical ablation of AF, most frequently performed via the Cox-Maze IV procedure, is highly effective in restoring sinus rhythm. Despite robust society guideline recommendations for concomitant surgical ablation (CSA) for AF, the practice has yet to be widely adopted. In this review, we discuss the current indications for CSA, its efficacy in maintaining freedom from atrial tachyarrhythmias, stroke, and adverse long-ter...
Source: The American Journal of Cardiology - May 1, 2024 Category: Cardiology Authors: Raghav Chandra, Jason Guo, Jewon Sohn, Michael E. Jessen, Christopher A. Heid Source Type: research
Editorial Board
(Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - April 30, 2024 Category: Cardiology Source Type: research
Contents
(Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - April 30, 2024 Category: Cardiology Source Type: research
