Predicting the cognitive impairment with multimodal ophthalmic imaging and artificial neural network for community screening
CONCLUSIONS: This study demonstrates retinal spectral signature alteration, neurodegeneration and angiopathy occur concurrently in cognitive impairment. The combination of multimodal ophthalmic imaging and BPNN can be a useful tool for predicting cognitive impairment with high performance for community screening.PMID:38697799 | DOI:10.1136/bjo-2023-323283 (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - May 2, 2024 Category: Opthalmology Authors: Zi Jin Xuhui Chen Chunxia Jiang Ximeng Feng Da Zou Yanye Lu Jinying Li Qiushi Ren Chuanqing Zhou Source Type: research

Creating realistic anterior segment optical coherence tomography images using generative adversarial networks
CONCLUSIONS: This study successfully developed and leveraged GANs capable of generating high-definition synthetic AS-OCT images that are realistic and suitable for machine learning and image analysis tasks.PMID:38697800 | DOI:10.1136/bjo-2023-324633 (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - May 2, 2024 Category: Opthalmology Authors: Jad F Assaf Anthony Abou Mrad Dan Z Reinstein Guillermo Amescua Cyril Zakka Timothy J Archer Jeffrey Yammine Elsa Lamah Mich èle Haykal Shady T Awwad Source Type: research

Proliferative vitreoretinopathy: a revised concept of retinal injury and response
Br J Ophthalmol. 2024 May 2:bjo-2023-324417. doi: 10.1136/bjo-2023-324417. Online ahead of print.ABSTRACTPrevious concepts for the pathogenesis of proliferative vitreoretinopathy (PVR) have focused on the central role of retinal pigment epithelium cells only, potentially contributing to the lack of clinical advances. More recent studies have demonstrated the essential role of retinal glial cells in the PVR healing response but failed to identify a consistent triggering mechanism.We propose a revised concept for the pathogenesis of PVR based on retinal injury and response. A posterior vitreous detachment (PVD) is invariably...
Source: The British Journal of Ophthalmology - May 2, 2024 Category: Opthalmology Authors: Alexandre Assi David Charteris Source Type: research

Predicting the cognitive impairment with multimodal ophthalmic imaging and artificial neural network for community screening
CONCLUSIONS: This study demonstrates retinal spectral signature alteration, neurodegeneration and angiopathy occur concurrently in cognitive impairment. The combination of multimodal ophthalmic imaging and BPNN can be a useful tool for predicting cognitive impairment with high performance for community screening.PMID:38697799 | DOI:10.1136/bjo-2023-323283 (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - May 2, 2024 Category: Opthalmology Authors: Zi Jin Xuhui Chen Chunxia Jiang Ximeng Feng Da Zou Yanye Lu Jinying Li Qiushi Ren Chuanqing Zhou Source Type: research

Creating realistic anterior segment optical coherence tomography images using generative adversarial networks
CONCLUSIONS: This study successfully developed and leveraged GANs capable of generating high-definition synthetic AS-OCT images that are realistic and suitable for machine learning and image analysis tasks.PMID:38697800 | DOI:10.1136/bjo-2023-324633 (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - May 2, 2024 Category: Opthalmology Authors: Jad F Assaf Anthony Abou Mrad Dan Z Reinstein Guillermo Amescua Cyril Zakka Timothy J Archer Jeffrey Yammine Elsa Lamah Mich èle Haykal Shady T Awwad Source Type: research

Proliferative vitreoretinopathy: a revised concept of retinal injury and response
Br J Ophthalmol. 2024 May 2:bjo-2023-324417. doi: 10.1136/bjo-2023-324417. Online ahead of print.ABSTRACTPrevious concepts for the pathogenesis of proliferative vitreoretinopathy (PVR) have focused on the central role of retinal pigment epithelium cells only, potentially contributing to the lack of clinical advances. More recent studies have demonstrated the essential role of retinal glial cells in the PVR healing response but failed to identify a consistent triggering mechanism.We propose a revised concept for the pathogenesis of PVR based on retinal injury and response. A posterior vitreous detachment (PVD) is invariably...
Source: The British Journal of Ophthalmology - May 2, 2024 Category: Opthalmology Authors: Alexandre Assi David Charteris Source Type: research

Predicting the cognitive impairment with multimodal ophthalmic imaging and artificial neural network for community screening
CONCLUSIONS: This study demonstrates retinal spectral signature alteration, neurodegeneration and angiopathy occur concurrently in cognitive impairment. The combination of multimodal ophthalmic imaging and BPNN can be a useful tool for predicting cognitive impairment with high performance for community screening.PMID:38697799 | DOI:10.1136/bjo-2023-323283 (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - May 2, 2024 Category: Opthalmology Authors: Zi Jin Xuhui Chen Chunxia Jiang Ximeng Feng Da Zou Yanye Lu Jinying Li Qiushi Ren Chuanqing Zhou Source Type: research

Creating realistic anterior segment optical coherence tomography images using generative adversarial networks
CONCLUSIONS: This study successfully developed and leveraged GANs capable of generating high-definition synthetic AS-OCT images that are realistic and suitable for machine learning and image analysis tasks.PMID:38697800 | DOI:10.1136/bjo-2023-324633 (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - May 2, 2024 Category: Opthalmology Authors: Jad F Assaf Anthony Abou Mrad Dan Z Reinstein Guillermo Amescua Cyril Zakka Timothy J Archer Jeffrey Yammine Elsa Lamah Mich èle Haykal Shady T Awwad Source Type: research

Proliferative vitreoretinopathy: a revised concept of retinal injury and response
Br J Ophthalmol. 2024 May 2:bjo-2023-324417. doi: 10.1136/bjo-2023-324417. Online ahead of print.ABSTRACTPrevious concepts for the pathogenesis of proliferative vitreoretinopathy (PVR) have focused on the central role of retinal pigment epithelium cells only, potentially contributing to the lack of clinical advances. More recent studies have demonstrated the essential role of retinal glial cells in the PVR healing response but failed to identify a consistent triggering mechanism.We propose a revised concept for the pathogenesis of PVR based on retinal injury and response. A posterior vitreous detachment (PVD) is invariably...
Source: The British Journal of Ophthalmology - May 2, 2024 Category: Opthalmology Authors: Alexandre Assi David Charteris Source Type: research

Age-period-cohort analysis of the global burden of visual impairment according to major causes: an analysis of the Global Burden of Disease Study 2019
CONCLUSIONS: The wide heterogeneity in age-period-cohort effects reflects different stages of societal transition and vision health. The unfavourable trends in age-period-cohort effects on disease prevalence identified in specific groups provide key information that may be used to identify priority groups in need of treatment and prevention.PMID:38664003 | DOI:10.1136/bjo-2023-324086 (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - April 25, 2024 Category: Opthalmology Authors: Jianqi Chen Yingting Zhu Zhidong Li Xiaohua Zhuo Shaochong Zhang Yehong Zhuo Source Type: research

Survival of medical treatment success in primary open-angle glaucoma and ocular hypertension
CONCLUSION: Large-scale survival analyses provide the expected duration of treatment success from topical glaucoma medication.PMID:38664004 | DOI:10.1136/bjo-2023-323708 (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - April 25, 2024 Category: Opthalmology Authors: Dun Jack Fu Ebenezer Ademisoye Vanessa Shih Andrew Ian McNaught Anthony Khawaja Source Type: research

Age-period-cohort analysis of the global burden of visual impairment according to major causes: an analysis of the Global Burden of Disease Study 2019
CONCLUSIONS: The wide heterogeneity in age-period-cohort effects reflects different stages of societal transition and vision health. The unfavourable trends in age-period-cohort effects on disease prevalence identified in specific groups provide key information that may be used to identify priority groups in need of treatment and prevention.PMID:38664003 | DOI:10.1136/bjo-2023-324086 (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - April 25, 2024 Category: Opthalmology Authors: Jianqi Chen Yingting Zhu Zhidong Li Xiaohua Zhuo Shaochong Zhang Yehong Zhuo Source Type: research

Survival of medical treatment success in primary open-angle glaucoma and ocular hypertension
CONCLUSION: Large-scale survival analyses provide the expected duration of treatment success from topical glaucoma medication.PMID:38664004 | DOI:10.1136/bjo-2023-323708 (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - April 25, 2024 Category: Opthalmology Authors: Dun Jack Fu Ebenezer Ademisoye Vanessa Shih Andrew Ian McNaught Anthony Khawaja Source Type: research

Age-period-cohort analysis of the global burden of visual impairment according to major causes: an analysis of the Global Burden of Disease Study 2019
CONCLUSIONS: The wide heterogeneity in age-period-cohort effects reflects different stages of societal transition and vision health. The unfavourable trends in age-period-cohort effects on disease prevalence identified in specific groups provide key information that may be used to identify priority groups in need of treatment and prevention.PMID:38664003 | DOI:10.1136/bjo-2023-324086 (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - April 25, 2024 Category: Opthalmology Authors: Jianqi Chen Yingting Zhu Zhidong Li Xiaohua Zhuo Shaochong Zhang Yehong Zhuo Source Type: research

Survival of medical treatment success in primary open-angle glaucoma and ocular hypertension
CONCLUSION: Large-scale survival analyses provide the expected duration of treatment success from topical glaucoma medication.PMID:38664004 | DOI:10.1136/bjo-2023-323708 (Source: The British Journal of Ophthalmology)
Source: The British Journal of Ophthalmology - April 25, 2024 Category: Opthalmology Authors: Dun Jack Fu Ebenezer Ademisoye Vanessa Shih Andrew Ian McNaught Anthony Khawaja Source Type: research