Mitral valve surgery in patients with Marfan syndrome
To review the pathology of the mitral valve (MV) and long-term outcomes of surgery in patients with Marfan syndrome (MFS). (Source: The Journal of Thoracic and Cardiovascular Surgery)
Source: The Journal of Thoracic and Cardiovascular Surgery - April 27, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Tirone E. David, Joy Park, Chun-Po Steve Fan Tags: Adult Source Type: research

Transient receptor potential vanilloid 4 channel inhibition attenuates lung ischemia-reperfusion injury in a porcine lung transplant model
Transient receptor potential vanilloid 4 (TRPV4) is a nonselective cation channel important in many physiological and pathophysiological processes, including pulmonary disease. Using a murine model, we previously demonstrated that TRPV4 mediates lung ischemia-reperfusion injury, the major cause of primary graft dysfunction after transplant. The current study tests the hypothesis that treatment with a TRPV4 inhibitor will attenuate lung ischemia-reperfusion injury in a clinically relevant porcine lung transplant model. (Source: The Journal of Thoracic and Cardiovascular Surgery)
Source: The Journal of Thoracic and Cardiovascular Surgery - April 27, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Raymond J. Strobel, Huy Q. Ta, Andrew M. Young, Alex M. Wisniewski, Anthony V. Norman, Evan P. Rotar, Mark H. Stoler, Irving L. Kron, Swapnil K. Sonkusare, Mark E. Roeser, Victor E. Laubach Tags: Thoracic Source Type: research

Reply: Defining successful decannulation from extracorporeal life support (ECLS)
We appreciate the interest in our article and commentary by Mariani and colleagues1 regarding our retrospective, single-center study of outcomes of patients successfully weaned from extracorporeal life support.2 First, we agree wholeheartedly that there is a need for standardized language in the extracorporeal membrane oxygenation (ECMO) space regarding what defines successful decannulation/weaning, myocardial recovery. In addition, we applaud Dr Mariani's and Dr Lorruso's team's efforts to shed light on reporting differences in the literature and define the “venoarterial-ECMO gap,” or the patients who are weaned from ...
Source: The Journal of Thoracic and Cardiovascular Surgery - April 27, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Ashley Zhang, Koji Takeda Tags: Letter to the Editor Source Type: research

The American Association for Thoracic Surgery (AATS) 2024 Expert Consensus Document: Management of neonates and infants with Ebstein anomaly.
Symptomatic neonates and infants with Ebstein Anomaly (EA) require complex management. A group of experts was commissioned by the American Association for Thoracic Surgery to provide a framework on this topic focusing on risk stratification and management. (Source: The Journal of Thoracic and Cardiovascular Surgery)
Source: The Journal of Thoracic and Cardiovascular Surgery - April 27, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Igor E. Konstantinov, Paul Chai, Emile Bacha, Christopher A. Caldarone, Jose Pedro Da Silva, Luciana Da Fonseca Da Silva, Joseph Dearani, Lisa Hornberger, Christopher Knott-Craig, Pedro del Nido, Muhammad Qureshi, George Sarris, Vaughn Starnes, Victor Tsa Source Type: research

Personalizing Patient Risk of a Life Altering Event: An Application of Machine Learning to Hemiarch Surgery
To assess a machine learning model ’s ability to predict the occurrence of life altering events (LAE) in hemiarch surgery and determine contributing patient characteristics and intraoperative factors. (Source: The Journal of Thoracic and Cardiovascular Surgery)
Source: The Journal of Thoracic and Cardiovascular Surgery - April 27, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Adam M. Carroll, Nicolas Chanes, Ananya Shah, Lance Dzubinski, Muhammad Aftab, T. Brett Reece Source Type: research

Artificial intelligence: the future of cardiothoracic surgery
Artificial intelligence (AI) is a rapidly emerging field of computer science with a significant predicted impact in cardiothoracic surgery. We investigate the role of this tool in the preoperative planning, intraoperative assistance, and postoperative management of patients. We also describe the future applications in the field and provide an insight on the advancements we have made at our institution. (Source: The Journal of Thoracic and Cardiovascular Surgery)
Source: The Journal of Thoracic and Cardiovascular Surgery - April 27, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Yash Pradeep Vaidya, Sara Jane Shumway Source Type: research

Transcatheter Heart Valve Explantation for TAVR Failure (TAVR-Explant): A Heart Valve Collaboratory Expert Consensus Document on Operative Techniques
(Source: The Journal of Thoracic and Cardiovascular Surgery)
Source: The Journal of Thoracic and Cardiovascular Surgery - April 24, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Tsuyoshi Kaneko, Vinayak N. Bapat, Ali M. Alakhtar, Syed Zaid, Isaac George, Kendra J. Grubb, Katherine Harrington, Luigi Pirelli, Marvin Atkins, Nimesh D. Desai, Sabine Bleiziffer, Thilo Noack, Thomas Modine, Paolo Denti, Joerg Kempfert, Hendrik Ruge, Ke Source Type: research

Cell-free DNA assay for malignancy classification of high-risk lung nodules.
Although low-dose computed tomography has been proven effective to reduce lung cancer-specific mortality, a considerable proportion of surgically resected high-risk lung nodules were still confirmed pathologically benign. There is an unmet need of a novel method for malignancy classification in lung nodules. (Source: The Journal of Thoracic and Cardiovascular Surgery)
Source: The Journal of Thoracic and Cardiovascular Surgery - April 24, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Siwei Wang, Fanchen Meng, Peng Chen, Yang Lv, Min Wu, Haimeng Tang, Hua Bao, Xue Wu, Yang Shao, Jie Wang, Juncheng Dai, Lin Xu, Xiaoxiao Wang, Rong Yin Source Type: research

Reply: Neoaortic root dilatation after arterial switch: The value of neoaortic root reduction
We read with interest the insightful comments of Dr Lacour-Gayet1 related to our recent article.2 It has previously been demonstrated that predictors for neoaortic root reoperation were either associated with an enlarged neoaortic root (ie, Taussig-Bing anomaly, previous pulmonary artery banding) or the neoaortic valve/subvalvular area (ie, bicuspid neoaortic valve, left ventricular outflow tract obstruction) before arterial switch operation.2,3 As Dr Lacour-Gayet  alludes to, further enlargement of the sinotubular junction after coronary artery transfer may potentially occur intraoperatively. (Source: The Journal of Thor...
Source: The Journal of Thoracic and Cardiovascular Surgery - April 23, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Tyson A. Fricke, Igor E. Konstantinov Tags: Letter to the Editor Source Type: research

The impact of permanent pacemaker implantation on long-term survival following cardiac surgery; A systematic review and meta-analysis
The long-term impact of permanent pacemaker (PPM) implantation on survival following cardiac surgery remains ill defined. We aimed to investigate the impact of PPM on survival and explore factors driving outcomes using meta-regression according to the type of surgery. (Source: The Journal of Thoracic and Cardiovascular Surgery)
Source: The Journal of Thoracic and Cardiovascular Surgery - April 22, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Yosuke Sakurai, J Hunter Mehaffey, Toshiki Kuno, Yujiro Yokoyama, Hisato Takagi, David A. Denning, Tsuyoshi Kaneko, Vinay Badhwar Source Type: research

Neoadjuvant, Perioperative, or Adjuvant Immunotherapy in Resectable NSCLC: How Do I Choose? Importance of Immune Biomarkers and Molecular Testing
(Source: The Journal of Thoracic and Cardiovascular Surgery)
Source: The Journal of Thoracic and Cardiovascular Surgery - April 20, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Jay M. Lee Source Type: research

Interhospital Variability in Cardiac Rehabilitation Use After Cardiac Surgery Among Medicare Beneficiaries
This study evaluated determinants of interhospital variability in CR use and outcomes. (Source: The Journal of Thoracic and Cardiovascular Surgery)
Source: The Journal of Thoracic and Cardiovascular Surgery - April 20, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Maximilian A. Fliegner, Hechuan Hou, Tyler M. Bauer, Temilolaoluwa Daramola, Jeffrey S. McCullough, Francis D. Pagani, Devraj Sukul, Donald S. Likosky, Steven J. Keteyian, Michael P. Thompson Source Type: research

Locally Advanced Esophageal Cancer Patients With Complete Clinical Response Post Neoadjuvant Chemoradiotherapy: A Markov Decision Analysis of Esophagectomy versus Active Surveillance
This study aims to compare surgery versus active surveillance for LAEC patients with complete clinical response (cCR) after neoadjuvant chemoradiotherapy (nCRT). (Source: The Journal of Thoracic and Cardiovascular Surgery)
Source: The Journal of Thoracic and Cardiovascular Surgery - April 19, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Adom Bondzi-Simpson, Tiago Ribeiro, Angelo Grant, Michael Ko, Natalie Coburn, Julie Hallet, Girish S. Kulkarni, Biniam Kidane Source Type: research

Discussion to: What drives variability in postoperative transfusion rates?
Presenter: Carrinton Mauney (Source: The Journal of Thoracic and Cardiovascular Surgery)
Source: The Journal of Thoracic and Cardiovascular Surgery - April 18, 2024 Category: Cardiovascular & Thoracic Surgery Tags: Perioperative Management Source Type: research

Discussion to: Implantation of the HeartMate 3 left ventricular assist device using a thoracotomy-based implant technique: Multicenter HeartMate 3 SWIFT study
Presenter: Dr Igor Gosev (Source: The Journal of Thoracic and Cardiovascular Surgery)
Source: The Journal of Thoracic and Cardiovascular Surgery - April 18, 2024 Category: Cardiovascular & Thoracic Surgery Tags: Adult Source Type: research