Morphometric Analysis of Cervical Neuroforaminal Dimensions from C2-T1 Using Computed Tomography of 1,000 Patients
Race and sex differences are not consistently reported in the literature. Fundamentally, anatomical differences of cervical neuroforaminal dimensions (CNFD) amongst these groups would be important to know. (Source: The Spine Journal)
Source: The Spine Journal - May 3, 2024 Category: Orthopaedics Authors: Jacob Razzouk, Trevor Case, Ethan Vyhmeister, Kai Nguyen, Davis Carter, Mei Carter, Grant Sajdak, Mikayla Kricfalusi, Rachel Taylor, Derran Bedward, David Shin, Nathaniel Wycliffe, Omar Ramos, Shaina A. Lipa, Christopher M. Bono, Wayne Cheng, Olumide Dani Tags: Clinical Study Source Type: research

The Effect of Cannabinoids on Single-level Lumbar Arthrodesis Outcomes in a Rat Model
The opioid epidemic is a public health crisis affecting spine care and pain management. Medical marijuana is a potential non-opioid analgesic yet to be studied in the surgical setting since its effects on bone healing are not fully understood. Studies have demonstrated analgesic and potentially osteoinductive properties of cannabinoids with endocannabinoid receptor expression in bone tissue. (Source: The Spine Journal)
Source: The Spine Journal - May 2, 2024 Category: Orthopaedics Authors: Harold Fogel, Diana Yeritsyan, Kaveh Momenzadeh, Nadim Kheir, Caleb M. Yeung, Mohammadreza Abbasian, Edith Martinez Lozano, Rosalynn M. Nazarian, Ara Nazarian Tags: Basic Science Source Type: research

Accurate placement of thoracolumbar pedicle screws using a handheld iOS-based navigation device: a prospective intra-patient agreement study
Accurate pedicle screw placement is a challenge with reported misplacement rates of 10% and higher. A handheld navigation device (HND) may provide accuracy equal to CT-based navigation (CT-Nav) but without the cost and complexity. (Source: The Spine Journal)
Source: The Spine Journal - May 1, 2024 Category: Orthopaedics Authors: Mark P. Arts, Geert Lycklama à Nijeholt, Eddie Van Eeckhoven, Jasper F.C. Wolfs Tags: Clinical Study Source Type: research

Complications and Outcomes After Three-Column Osteotomy: A 5-Year Follow-up
Three-column spinal osteotomies (3-CO) are powerful techniques used to correct spinal deformity. These surgeries are associated with an elevated risk of complications. While outcomes have been reported in the literature with 2 years follow-up, longer-term outcomes of three-column osteotomies remain understudied. (Source: The Spine Journal)
Source: The Spine Journal - April 29, 2024 Category: Orthopaedics Authors: Andrew N. Corbett, Biodun Adeniyi, Brandon A. Simonetta, Dennis G. Crandall, Michael S. Chang Tags: Clinical Study Source Type: research

The biomechanical effect of lumbopelvic distance reduction on reconstruction after total sacrectomy: a comparative finite element analysis of four techniques
The lumbosacral complex serves as a biomechanical keystone, transmitting the forces from the axial skeleton to the lower limbs [1,2]. It plays a crucial role in maintaining an upright posture and enabling the ability to walk [3]. If this anatomical junction is affected by primary malignant sacral tumors [4 –6], surgical interventions invariably emerge as the preferred treatment strategy. However, the surgical treatment of sacral tumors is technically demanding and necessitates careful consideration of anatomical and biomechanical factors [2,7,8]. (Source: The Spine Journal)
Source: The Spine Journal - April 27, 2024 Category: Orthopaedics Authors: Mate Turbucz, Agoston Jakab Pokorni, Benjamin Hajnal, Kristof Koch, Zsolt Szoverfi, Peter Pal Varga, Aron Lazary, Peter Endre Eltes Source Type: research

Posterior Atlantoaxial Fixation of Osteoporotic Odontoid Fracture: Biomechanical Analysis of the Magerl versus Harms Techniques in a Cadaver Model.
Odontoid fractures are among the most common cervical spine fractures in the elderly and are associated with increased morbidity and mortality. Clinical evidence suggests improved survival and quality of life after operative intervention compared to nonoperative treatment. (Source: The Spine Journal)
Source: The Spine Journal - April 27, 2024 Category: Orthopaedics Authors: Austin Mike-Mayer, Kendrick Lam, Randal P. Morris, Abeer Al Barghouthi, Francesco Travascio, Loren L. Latta, Ronald W. Lindsey Tags: Basic Science Source Type: research

Transabdominal Motor Evoked Potential Neuromonitoring of Lumbosacral Spine Surgery
Transcranial Motor Evoked Potentials (TcMEPs) can improve intraoperative detection of femoral plexus and nerve root injury during lumbosacral spine surgery. However, even under ideal conditions, TcMEPs are not completely free of false-positive alerts due to the immobilizing effect of general anesthetics, especially in the proximal musculature. The application of transcutaneous stimulation to activate ventral nerve roots directly at the level of the conus medularis (bypassing the brain and spinal cord) has emerged as a method to potentially monitor the motor component of the femoral plexus and lumbosacral nerves free from t...
Source: The Spine Journal - April 27, 2024 Category: Orthopaedics Authors: David W. Allison, Amit Verma, Paul J. Holman, Meng Huang, Todd W. Trask, Sean M. Barber, Anthony R. Cockrell, Matthew R. Weber, Dalton W. Brooks, Leo Delgado, William J. Steele, Jonathan N. Sellin, Loyola V. Gressot, Bradley Lambert, Brandy B. Ma, Amir H. Tags: Clinical Study Source Type: research

Poor postoperative pain control is associated with poor long-term patient-reported outcomes after elective spine surgery: an observational cohort study
A significant proportion of patients experience poorly controlled surgical pain and fail to achieve satisfactory clinical improvement after spine surgery. However, a direct association between these variables has not been previously demonstrated. (Source: The Spine Journal)
Source: The Spine Journal - April 27, 2024 Category: Orthopaedics Authors: Michael M.H. Yang, Rena Far, Jay Riva-Cambrin, Tolulope T. Sajobi, Steven Casha Tags: Clinical Study Source Type: research

S1 vertebral bone quality score independently predicts pedicle screw loosening following surgery in patients with adult degenerative scoliosis
MRI-based vertebral bone quality (VBQ) score is an effective predictor of pedicle screw loosening after lumbar fusion surgery and has been recognized as a valuable tool for assessing preoperative bone quality. Due to the lateral curvature of lumbar spine of degenerative scoliosis, accurate measurement of VBQ score by conventional measurement methods that capture MRI signal intensity at L1-4 may be limited under certain conditions. To this end, a new simplified S1 VBQ score method has been proposed, which is comparable to the previous L1-4 VBQ score or S1 Hounsfield unit (HU) value, and has high accuracy and reliability. (S...
Source: The Spine Journal - April 27, 2024 Category: Orthopaedics Authors: Qiujiang Li, Junhu Li, Huiliang Yang, Xi Yang, Lei Wang, Yueming Song Tags: Clinical Study Source Type: research

Which patients do we need to consider augmentation of muscle active potentials regarding transcranial electrical stimulation motor-evoked potentials monitoring before spine surgery?
Intraoperative neurophysiological monitoring (IONM) is important to prevent spinal cord or nerve root injuries during spinal surgery. Among the various modalities, transcranial electrical stimulation motor-evoked potentials (Tc-MEPs) have been widely used for IONM to assess motor pathway damage [1,2]. However, the amplitudes of compound muscle action potentials (CMAPs) can be suppressed by anesthetics and neuromuscular blockers [2,3]. Furthermore, patient-related factors such as preoperative motor deficits, age, presence of a lesion in the spinal cord, and endogenous diseases may also affect CMAPs [4 –7]. (Source: The Spine Journal)
Source: The Spine Journal - April 26, 2024 Category: Orthopaedics Authors: Takahiro Mui, Hideki Shigematsu, Tsunenori Takatani, Masaki Ikejiri, Sachiko Kawasaki, Hironobu Hayashi, Masahiko Kawaguchi, Yasuhito Tanaka Tags: Clinical Study Source Type: research

Therapeutic efficacy of adrenergic agents on systemic and spinal hemodynamics in an acute cervical spinal cord injury rodent model
Cervical spinal cord injury usually results in cardiorespiratory dysfunctions due to interruptions of the bulbospinal pathways innervating the cervical phrenic motoneurons and thoracic sympathetic preganglionic neurons. (Source: The Spine Journal)
Source: The Spine Journal - April 26, 2024 Category: Orthopaedics Authors: Kun-Ze Lee, Tzu-Ting Liu, Rui-Yi Chen Tags: Basic Science Source Type: research

Utility of somatosensory- and motor-evoked potential change thresholds in surgical treatment for thoracic spinal stenosis based on different pathologies.
: Thoracic spinal stenosis (TSS) is secondary to different pathologies that differ in clinical characteristics and surgical outcomes. (Source: The Spine Journal)
Source: The Spine Journal - April 26, 2024 Category: Orthopaedics Authors: Tun Liu, Gang Wu, Wentao Wang, Huaguang Qi, Songchuan Zhao, Jitao Zhang, Ruiguo Wang, Tao Yuan, Li Xiao, Zhenguo Luo, Weizhou Yang, Fei Wang, Gang Wang, Liang Yan Tags: Clinical Study Source Type: research

Pre-operative expectations of patients with Degenerative Cervical Myelopathy: An observational study from the Canadian Spine Outcomes and Research Network
Patients' expectations play a crucial role in the overall success and satisfaction with surgical outcomes. A patient's perception of the anticipated results, recovery process, and potential complications can influence their psychological and emotional well-being throughout their healthcare journey. Patients have a range of expectations, influenced by various factors: personal beliefs, cultural background, and previous medical experiences. Addressing these expectations allows healthcare providers to build trust, mitigate anxiety, and possibly enhance patient compliance with preoperative and postoperative instructions. (Sour...
Source: The Spine Journal - April 26, 2024 Category: Orthopaedics Authors: Alwalaa Althagafi, Nicolas Dea, Nathan Evaniew, Raja Y Rampersaud, W. Bradley Jacobs, J érome Paquet, Jefferson R Wilson, Hamilton Hall, Christopher S. Bailey, Michael H. Weber, Andrew Nataraj, Najmedden Attabib, David W. Cadotte, Philippe Phan, Sean D. Tags: Clinical Study Source Type: research

Advanced MRI metrics improve the prediction of baseline disease severity for individuals with degenerative cervical myelopathy
Degenerative cervical myelopathy (DCM) is the most common form of atraumatic spinal cord injury globally. Degeneration of spinal discs, bony osteophyte growth and ligament pathology results in physical compression of the spinal cord contributing to damage of white matter tracts and grey matter cellular populations. This results in an insidious neurological and functional decline in patients which can lead to paralysis. Magnetic resonance imaging (MRI) confirms the diagnosis of DCM and is a prerequisite to surgical intervention, the only known treatment for this disorder. (Source: The Spine Journal)
Source: The Spine Journal - April 26, 2024 Category: Orthopaedics Authors: Abdul Al-Shawwa, Kalum Ost, David Anderson, Newton Cho, Nathan Evaniew, W. Bradley Jacobs, Allan R. Martin, Ranjeet Gaekwad, Saswati Tripathy, Jacques Bouchard, Steven Casha, Roger Cho, Stephen duPlessis, Peter Lewkonia, Fred Nicholls, Paul T. Salo, Alex Tags: Clinical Study Source Type: research

Development and Validation of a Radiomics-Based Model for Predicting Osteoporosis in Patients with Lumbar Compression Fractures
Osteoporosis, a metabolic bone disorder, markedly elevates fracture risks, with vertebral compression fractures being predominant. Antiosteoporotic treatments for patients with osteoporotic vertebral compression fractures (OVCF) lessen both the occurrence of subsequent fractures and associated pain. Thus, diagnosing osteoporosis in OVCF patients is vital. (Source: The Spine Journal)
Source: The Spine Journal - April 26, 2024 Category: Orthopaedics Authors: Sunqi Nian, Yayu Zhao, Chengjin Li, Kang Zhu, Na Li, Weichao Li, Jiayu Chen Tags: Clinical Study Source Type: research