Origin, identity, and function of terminal Schwann cells
Trends Neurosci. 2024 Apr 24:S0166-2236(24)00055-9. doi: 10.1016/j.tins.2024.03.007. Online ahead of print.ABSTRACTThe highly specialized nonmyelinating glial cells present at somatic peripheral nerve endings, known collectively as terminal Schwann cells (TSCs), play critical roles in the development, function and repair of their motor and sensory axon terminals and innervating tissue. Over the past decades, research efforts across various vertebrate species have revealed that while TSCs are a diverse group of cells, they share a number of features among them. In this review, we summarize the state-of-knowledge about each ...
Source: Trends in Neurosciences - April 25, 2024 Category: Neuroscience Authors: Robert Louis Hastings Gregorio Valdez Source Type: research
Window into the songbird brain reveals superdiffusive migration of adult-born neurons
This study highlights the value of ubiquitin C/green fluorescent protein (UBC-GFP) transgenic zebra finches in studying adult neurogenesis and advances our understanding of dispersed long-distance neuronal migration in the adult brain, shedding light on this understudied phenomenon.PMID:38664110 | DOI:10.1016/j.tins.2024.04.001 (Source: Trends in Neurosciences)
Source: Trends in Neurosciences - April 25, 2024 Category: Neuroscience Authors: Carolyn L Pytte Source Type: research
Origin, identity, and function of terminal Schwann cells
Trends Neurosci. 2024 Apr 24:S0166-2236(24)00055-9. doi: 10.1016/j.tins.2024.03.007. Online ahead of print.ABSTRACTThe highly specialized nonmyelinating glial cells present at somatic peripheral nerve endings, known collectively as terminal Schwann cells (TSCs), play critical roles in the development, function and repair of their motor and sensory axon terminals and innervating tissue. Over the past decades, research efforts across various vertebrate species have revealed that while TSCs are a diverse group of cells, they share a number of features among them. In this review, we summarize the state-of-knowledge about each ...
Source: Trends in Neurosciences - April 25, 2024 Category: Neuroscience Authors: Robert Louis Hastings Gregorio Valdez Source Type: research
Window into the songbird brain reveals superdiffusive migration of adult-born neurons
This study highlights the value of ubiquitin C/green fluorescent protein (UBC-GFP) transgenic zebra finches in studying adult neurogenesis and advances our understanding of dispersed long-distance neuronal migration in the adult brain, shedding light on this understudied phenomenon.PMID:38664110 | DOI:10.1016/j.tins.2024.04.001 (Source: Trends in Neurosciences)
Source: Trends in Neurosciences - April 25, 2024 Category: Neuroscience Authors: Carolyn L Pytte Source Type: research
Origin, identity, and function of terminal Schwann cells
Trends Neurosci. 2024 Apr 24:S0166-2236(24)00055-9. doi: 10.1016/j.tins.2024.03.007. Online ahead of print.ABSTRACTThe highly specialized nonmyelinating glial cells present at somatic peripheral nerve endings, known collectively as terminal Schwann cells (TSCs), play critical roles in the development, function and repair of their motor and sensory axon terminals and innervating tissue. Over the past decades, research efforts across various vertebrate species have revealed that while TSCs are a diverse group of cells, they share a number of features among them. In this review, we summarize the state-of-knowledge about each ...
Source: Trends in Neurosciences - April 25, 2024 Category: Neuroscience Authors: Robert Louis Hastings Gregorio Valdez Source Type: research
Window into the songbird brain reveals superdiffusive migration of adult-born neurons
This study highlights the value of ubiquitin C/green fluorescent protein (UBC-GFP) transgenic zebra finches in studying adult neurogenesis and advances our understanding of dispersed long-distance neuronal migration in the adult brain, shedding light on this understudied phenomenon.PMID:38664110 | DOI:10.1016/j.tins.2024.04.001 (Source: Trends in Neurosciences)
Source: Trends in Neurosciences - April 25, 2024 Category: Neuroscience Authors: Carolyn L Pytte Source Type: research
Origin, identity, and function of terminal Schwann cells
Trends Neurosci. 2024 Apr 24:S0166-2236(24)00055-9. doi: 10.1016/j.tins.2024.03.007. Online ahead of print.ABSTRACTThe highly specialized nonmyelinating glial cells present at somatic peripheral nerve endings, known collectively as terminal Schwann cells (TSCs), play critical roles in the development, function and repair of their motor and sensory axon terminals and innervating tissue. Over the past decades, research efforts across various vertebrate species have revealed that while TSCs are a diverse group of cells, they share a number of features among them. In this review, we summarize the state-of-knowledge about each ...
Source: Trends in Neurosciences - April 25, 2024 Category: Neuroscience Authors: Robert Louis Hastings Gregorio Valdez Source Type: research
Window into the songbird brain reveals superdiffusive migration of adult-born neurons
This study highlights the value of ubiquitin C/green fluorescent protein (UBC-GFP) transgenic zebra finches in studying adult neurogenesis and advances our understanding of dispersed long-distance neuronal migration in the adult brain, shedding light on this understudied phenomenon.PMID:38664110 | DOI:10.1016/j.tins.2024.04.001 (Source: Trends in Neurosciences)
Source: Trends in Neurosciences - April 25, 2024 Category: Neuroscience Authors: Carolyn L Pytte Source Type: research
Origin, identity, and function of terminal Schwann cells
Trends Neurosci. 2024 Apr 24:S0166-2236(24)00055-9. doi: 10.1016/j.tins.2024.03.007. Online ahead of print.ABSTRACTThe highly specialized nonmyelinating glial cells present at somatic peripheral nerve endings, known collectively as terminal Schwann cells (TSCs), play critical roles in the development, function and repair of their motor and sensory axon terminals and innervating tissue. Over the past decades, research efforts across various vertebrate species have revealed that while TSCs are a diverse group of cells, they share a number of features among them. In this review, we summarize the state-of-knowledge about each ...
Source: Trends in Neurosciences - April 25, 2024 Category: Neuroscience Authors: Robert Louis Hastings Gregorio Valdez Source Type: research
Window into the songbird brain reveals superdiffusive migration of adult-born neurons
This study highlights the value of ubiquitin C/green fluorescent protein (UBC-GFP) transgenic zebra finches in studying adult neurogenesis and advances our understanding of dispersed long-distance neuronal migration in the adult brain, shedding light on this understudied phenomenon.PMID:38664110 | DOI:10.1016/j.tins.2024.04.001 (Source: Trends in Neurosciences)
Source: Trends in Neurosciences - April 25, 2024 Category: Neuroscience Authors: Carolyn L Pytte Source Type: research
Equalizing transcallosal inhibition in the mouse anterior cingulate mitigates visuospatial neglect
Trends Neurosci. 2024 Apr 23:S0166-2236(24)00060-2. doi: 10.1016/j.tins.2024.04.002. Online ahead of print.ABSTRACTA recent study by Wang and colleagues disentangled a transcallosal inhibitory circuit in mouse anterior cingulate cortex (ACC), which modulates excitatory ipsilateral tonus and contralateral inhibition by exciting contralateral parvalbumin-positive (PV+) interneurons. The authors conclude that the identified circuit mediates interhemispheric balance for visuospatial attention and provides top-down modulation of visual cortices.PMID:38658244 | DOI:10.1016/j.tins.2024.04.002 (Source: Trends in Neurosciences)
Source: Trends in Neurosciences - April 24, 2024 Category: Neuroscience Authors: Kerstin Erika Schmidt Source Type: research
Advances in animal models of prenatal opioid exposure
Trends Neurosci. 2024 Apr 12:S0166-2236(24)00042-0. doi: 10.1016/j.tins.2024.03.005. Online ahead of print.ABSTRACTNeonatal opioid withdrawal syndrome (NOWS) is a growing public health concern. The complexity of in utero opioid exposure in clinical studies makes it difficult to investigate underlying mechanisms that could ultimately inform early diagnosis and treatments. Clinical studies are unable to dissociate the influence of maternal polypharmacy or the environment from direct effects of in utero opioid exposure, highlighting the need for effective animal models. Early animal models of prenatal opioid exposure primaril...
Source: Trends in Neurosciences - April 13, 2024 Category: Neuroscience Authors: Julia R Ferrante Julie A Blendy Source Type: research
Orchestrating neuronal activity-dependent translation via the integrated stress response protein GADD34
Trends Neurosci. 2024 Apr 12:S0166-2236(24)00058-4. doi: 10.1016/j.tins.2024.03.008. Online ahead of print.ABSTRACTIn a recent study, Oliveira and colleagues revealed how growth arrest and DNA damage-inducible protein 34 (GADD34), an effector of the integrated stress response, initiates the translation of synaptic plasticity-related mRNAs following brain-derived neurotrophic factor (BDNF) stimulation. This work suggests that GADD34 may link transcriptional products with translation control upon neuronal activation, illuminating how protein synthesis is orchestrated in neuronal plasticity.PMID:38614892 | DOI:10.1016/j.tins....
Source: Trends in Neurosciences - April 13, 2024 Category: Neuroscience Authors: Xingzhi He Wenwen Li Huan Ma Source Type: research
Advances in animal models of prenatal opioid exposure
Trends Neurosci. 2024 Apr 12:S0166-2236(24)00042-0. doi: 10.1016/j.tins.2024.03.005. Online ahead of print.ABSTRACTNeonatal opioid withdrawal syndrome (NOWS) is a growing public health concern. The complexity of in utero opioid exposure in clinical studies makes it difficult to investigate underlying mechanisms that could ultimately inform early diagnosis and treatments. Clinical studies are unable to dissociate the influence of maternal polypharmacy or the environment from direct effects of in utero opioid exposure, highlighting the need for effective animal models. Early animal models of prenatal opioid exposure primaril...
Source: Trends in Neurosciences - April 13, 2024 Category: Neuroscience Authors: Julia R Ferrante Julie A Blendy Source Type: research
Orchestrating neuronal activity-dependent translation via the integrated stress response protein GADD34
Trends Neurosci. 2024 Apr 12:S0166-2236(24)00058-4. doi: 10.1016/j.tins.2024.03.008. Online ahead of print.ABSTRACTIn a recent study, Oliveira and colleagues revealed how growth arrest and DNA damage-inducible protein 34 (GADD34), an effector of the integrated stress response, initiates the translation of synaptic plasticity-related mRNAs following brain-derived neurotrophic factor (BDNF) stimulation. This work suggests that GADD34 may link transcriptional products with translation control upon neuronal activation, illuminating how protein synthesis is orchestrated in neuronal plasticity.PMID:38614892 | DOI:10.1016/j.tins....
Source: Trends in Neurosciences - April 13, 2024 Category: Neuroscience Authors: Xingzhi He Wenwen Li Huan Ma Source Type: research
