Incidence and management of prostatic urethra recurrence in a cohort of 21 patients who received BCG induction for non-muscle invasive bladder cancer
CONCLUSION: Patients with PU recurrences following intravesical BCG have a high-risk disease phenotype with a significant risk of recurrence. Conservative management may be appropriate for well-selected patients who do not desire a cystoprostatectomy.PMID:38688797 | DOI:10.1016/j.urolonc.2024.04.017 (Source: Urologic Oncology)
Source: Urologic Oncology - April 30, 2024 Category: Urology & Nephrology Authors: Justin W Ingram Rainjade Chung Caroline Laplaca James M McKiernan Andrew T Lenis Christopher B Anderson Source Type: research

Incidence and management of prostatic urethra recurrence in a cohort of 21 patients who received BCG induction for non-muscle invasive bladder cancer
CONCLUSION: Patients with PU recurrences following intravesical BCG have a high-risk disease phenotype with a significant risk of recurrence. Conservative management may be appropriate for well-selected patients who do not desire a cystoprostatectomy.PMID:38688797 | DOI:10.1016/j.urolonc.2024.04.017 (Source: Urologic Oncology)
Source: Urologic Oncology - April 30, 2024 Category: Urology & Nephrology Authors: Justin W Ingram Rainjade Chung Caroline Laplaca James M McKiernan Andrew T Lenis Christopher B Anderson Source Type: research

Cost of upper tract imaging obtained during hematuria evaluation: Analysis of a national claims database
CONCLUSIONS: In this nationally representative analysis, hematuria evaluation confers a significant cost burden, while the primary factor associated with higher costs of screening was imaging type. Based upon reduced cost of US-based strategies, further investigation should delineate its cost-effectiveness in the diagnosis of urological disease.PMID:38679529 | DOI:10.1016/j.urolonc.2024.03.008 (Source: Urologic Oncology)
Source: Urologic Oncology - April 28, 2024 Category: Urology & Nephrology Authors: Alex Hannemann Rodrigo Rodrigues Pessoa Thomas Flaig Elizabeth Molina Kuna Adam Warren Tyler Robin Simon P Kim Eric Ballon-Landa Source Type: research

Cost of upper tract imaging obtained during hematuria evaluation: Analysis of a national claims database
CONCLUSIONS: In this nationally representative analysis, hematuria evaluation confers a significant cost burden, while the primary factor associated with higher costs of screening was imaging type. Based upon reduced cost of US-based strategies, further investigation should delineate its cost-effectiveness in the diagnosis of urological disease.PMID:38679529 | DOI:10.1016/j.urolonc.2024.03.008 (Source: Urologic Oncology)
Source: Urologic Oncology - April 28, 2024 Category: Urology & Nephrology Authors: Alex Hannemann Rodrigo Rodrigues Pessoa Thomas Flaig Elizabeth Molina Kuna Adam Warren Tyler Robin Simon P Kim Eric Ballon-Landa Source Type: research

The emotional toll of surgical complications in the early career
Urol Oncol. 2024 Apr 26:S1078-1439(24)00425-3. doi: 10.1016/j.urolonc.2024.04.009. Online ahead of print.ABSTRACTSurgical complications and errors impact all surgeons throughout their career. Early career surgeons may be particularly vulnerable. In this invited manuscript the impact of surgical complications on early career surgeons is discussed. Review of current systems to aid in emotional support of complications is provided.PMID:38677938 | DOI:10.1016/j.urolonc.2024.04.009 (Source: Urologic Oncology)
Source: Urologic Oncology - April 27, 2024 Category: Urology & Nephrology Authors: Amy N Luckenbaugh Source Type: research

The emotional toll of surgical complications in the early career
Urol Oncol. 2024 Apr 26:S1078-1439(24)00425-3. doi: 10.1016/j.urolonc.2024.04.009. Online ahead of print.ABSTRACTSurgical complications and errors impact all surgeons throughout their career. Early career surgeons may be particularly vulnerable. In this invited manuscript the impact of surgical complications on early career surgeons is discussed. Review of current systems to aid in emotional support of complications is provided.PMID:38677938 | DOI:10.1016/j.urolonc.2024.04.009 (Source: Urologic Oncology)
Source: Urologic Oncology - April 27, 2024 Category: Urology & Nephrology Authors: Amy N Luckenbaugh Source Type: research

Patient- and caregiver-related factors affecting family caregiver burden of urologic cancer patients
CONCLUSION: Care recipient performance status was a strong patient-related factor associated with higher FC burden regardless of duration of caregiving and other caregiver-related factors after adjusting for caregiver demographics.PMID:38670816 | DOI:10.1016/j.urolonc.2024.04.004 (Source: Urologic Oncology)
Source: Urologic Oncology - April 26, 2024 Category: Urology & Nephrology Authors: Li Ping Wong Xiaonan Xu Haridah Alias Chuo Yew Ting Hui Meng Tan Yulan Lin Source Type: research

Histologic and molecular landscape of genitourinary tumors and clinical implications
Urol Oncol. 2024 Apr 26:S1078-1439(24)00434-4. doi: 10.1016/j.urolonc.2024.04.016. Online ahead of print.NO ABSTRACTPMID:38670817 | DOI:10.1016/j.urolonc.2024.04.016 (Source: Urologic Oncology)
Source: Urologic Oncology - April 26, 2024 Category: Urology & Nephrology Authors: Deepika Sirohi Source Type: research

Efficacy of conduction hyperthermia in the treatment of non-muscle invasive bladder cancer: A systematic review
CONCLUSIONS: Studies on conduction hyperthermia present great variability, which do not allow us to determine the superiority of 1 device over another in terms of recurrence, progression, and/or adverse effects. Further research with consistent administration protocols is crucial for definitive conclusions.PMID:38670818 | DOI:10.1016/j.urolonc.2024.03.013 (Source: Urologic Oncology)
Source: Urologic Oncology - April 26, 2024 Category: Urology & Nephrology Authors: M Teresa Melgarejo Segura Yaiza Y áñez Castillo Macarena Lozano Lorca Ana Morales Mart ínez Miguel Ángel Arrabal Polo Miguel Arrabal Mart ín Source Type: research

Voided urine cytology is a useful tool predicting non-muscle-invasive bladder cancer risk before surgery
CONCLUSIONS: VUC appears to be a good, inexpensive and easily available method to determine risk stratification before surgery. This can be useful in daily practice to determine which patients should receive a single instillation of MMC and to prioritize patients more likely to have a high- risk tumor.PMID:38664179 | DOI:10.1016/j.urolonc.2024.03.014 (Source: Urologic Oncology)
Source: Urologic Oncology - April 25, 2024 Category: Urology & Nephrology Authors: Carmen G ómez Del Cañizo Ignacio Gonz ález Ginel Cristina Mart ín-Arriscado Arroba Ana de la Calle Moreno Mario Hern ández Arroyo Alfredo Rodr íguez Antolín F élix Guerrero Ramos Source Type: research

An exploratory study investigating the impact of the bladder tumor microbiome on Bacillus Calmette Guerin (BCG) response in non-muscle invasive bladder cancer
CONCLUSION: A compositional difference exists in the tumor microbiome of BCG responders and non-responders with Lactobacillus having increased abundance in BCG responders.PMID:38664180 | DOI:10.1016/j.urolonc.2024.04.011 (Source: Urologic Oncology)
Source: Urologic Oncology - April 25, 2024 Category: Urology & Nephrology Authors: Jacob Knorr Zaeem Lone Glenn Werneburg Ava Adler Jose Agudelo Mangesh Suryavanshi Rebecca A Campbell Kyle Ericson Hong Qiu Petar Bajic Georges-Pascal Haber Christopher J Weight Philip P Ahern Nima Almassi Aaron W Miller Byron H Lee Source Type: research

Voided urine cytology is a useful tool predicting non-muscle-invasive bladder cancer risk before surgery
CONCLUSIONS: VUC appears to be a good, inexpensive and easily available method to determine risk stratification before surgery. This can be useful in daily practice to determine which patients should receive a single instillation of MMC and to prioritize patients more likely to have a high- risk tumor.PMID:38664179 | DOI:10.1016/j.urolonc.2024.03.014 (Source: Urologic Oncology)
Source: Urologic Oncology - April 25, 2024 Category: Urology & Nephrology Authors: Carmen G ómez Del Cañizo Ignacio Gonz ález Ginel Cristina Mart ín-Arriscado Arroba Ana de la Calle Moreno Mario Hern ández Arroyo Alfredo Rodr íguez Antolín F élix Guerrero Ramos Source Type: research

An exploratory study investigating the impact of the bladder tumor microbiome on Bacillus Calmette Guerin (BCG) response in non-muscle invasive bladder cancer
CONCLUSION: A compositional difference exists in the tumor microbiome of BCG responders and non-responders with Lactobacillus having increased abundance in BCG responders.PMID:38664180 | DOI:10.1016/j.urolonc.2024.04.011 (Source: Urologic Oncology)
Source: Urologic Oncology - April 25, 2024 Category: Urology & Nephrology Authors: Jacob Knorr Zaeem Lone Glenn Werneburg Ava Adler Jose Agudelo Mangesh Suryavanshi Rebecca A Campbell Kyle Ericson Hong Qiu Petar Bajic Georges-Pascal Haber Christopher J Weight Philip P Ahern Nima Almassi Aaron W Miller Byron H Lee Source Type: research

Impact of body composition on outcomes of immune checkpoint inhibitor combination therapy in patients with previously untreated advanced renal cell carcinoma
CONCLUSION: The SFI can be potentially utilized as an effective predictive and prognostic biomarker for first-line ICI combination therapy for advanced RCC.PMID:38653590 | DOI:10.1016/j.urolonc.2024.04.008 (Source: Urologic Oncology)
Source: Urologic Oncology - April 23, 2024 Category: Urology & Nephrology Authors: Hiroki Ishihara Koichi Nishimura Takashi Ikeda Hironori Fukuda Kazuhiko Yoshida Junpei Iizuka Tsunenori Kondo Toshio Takagi Source Type: research

Prognostic significance of lymph node count in surgically treated patients with T < sub > 2-4 < /sub > stage nonmetastatic adrenocortical carcinoma
CONCLUSIONS: Lymphadenectomy provides a prognostic benefit in nmACC patients and identifies pN1 patients with dismal prognosis. Conversely, in pN0 patients, a LNC cut-off ≥4 identifies those with particularly favorable prognosis.PMID:38653591 | DOI:10.1016/j.urolonc.2024.04.003 (Source: Urologic Oncology)
Source: Urologic Oncology - April 23, 2024 Category: Urology & Nephrology Authors: Anis Assad Francesco Barletta Reha-Baris Incesu Lukas Scheipner Simone Morra Andrea Baudo Cristina Cano Garcia Zhe Tian Sascha Ahyai Nicola Longo Felix K H Chun Shahrokh F Shariat Derya Tilki Alberto Briganti Fred Saad Pierre I Karakiewicz Source Type: research