Lessons we learned during the past four challenging years in the COVID-19 era: pharmacotherapy, long COVID complications, and vaccine development
About four years have passed since the detection of the first cases of COVID-19 in China. During this lethal pandemic, millions of people have lost their lives around the world. Since the first waves of COVID-... (Source: Virology Journal)
Source: Virology Journal - April 26, 2024 Category: Virology Authors: Parisa Ghasemiyeh and Soliman Mohammadi-Samani Tags: Review Source Type: research
Presepsin as a prognostic biomarker in COVID-19 patients: combining clinical scoring systems and laboratory inflammatory markers for outcome prediction
There is still limited research on the prognostic value of Presepsin as a biomarker for predicting the outcome of COVID-19 patients. Additionally, research on the combined predictive value of Presepsin with cl... (Source: Virology Journal)
Source: Virology Journal - April 26, 2024 Category: Virology Authors: Zhipeng Wu, Nan Geng, Zhao Liu, Wen Pan, Yueke Zhu, Jing Shan, Hongbo Shi, Ying Han, Yingmin Ma and Bo Liu Tags: Research Source Type: research
Vpr driving DNA methylation variation of CD4 + T cells in HIV-1 infection
Despite the existence of available therapeutic interventions for HIV-1, this virus remains a significant global threat, leading to substantial morbidity and mortality. Within HIV-1-infected cells, the accessor... (Source: Virology Journal)
Source: Virology Journal - April 26, 2024 Category: Virology Authors: Peipei Wang, Zhuoyue Meng, Kai Deng, Zhiliang Gao and Jinfeng Cai Tags: Research Source Type: research
Antiviral screening of natural, anti-inflammatory compound library against African swine fever virus
African swine fever virus (ASFV) is a major threat to pig production and the lack of effective vaccines underscores the need to develop robust antiviral countermeasures. Pathologically, a significant elevation... (Source: Virology Journal)
Source: Virology Journal - April 25, 2024 Category: Virology Authors: Joshua A. Jackman, Astghik Hakobyan, Rafayela Grigoryan, Roza Izmailyan, Charles C. Elrod and Hovakim Zakaryan Tags: Research Source Type: research
Evaluation of different genomic regions of rotavirus B and rotavirus C for development of real-time RT ‒PCR assays
The causative agents of diarrhea, rotavirus B (RVB) and rotavirus C (RVC) are common in adults and patients of all age groups, respectively. Due to the Rotavirus A (RVA) vaccination program, a significant decr... (Source: Virology Journal)
Source: Virology Journal - April 24, 2024 Category: Virology Authors: Madhuri S. Joshi, Manohar S. Shinde and Mallika Lavania Tags: Methodology Source Type: research
Resistance to African swine fever virus among African domestic pigs appears to be associated with a distinct polymorphic signature in the RelA gene and upregulation of RelA transcription
African swine fever virus (ASFV) is a highly contagious and fatal hemorrhagic disease of domestic pigs, which poses a major threat to the swine industry worldwide. Studies have shown that indigenous African pi... (Source: Virology Journal)
Source: Virology Journal - April 24, 2024 Category: Virology Authors: Patrick N. Bisimwa, Juliette R. Ongus, Ronald Tonui, Espoir B. Bisimwa and Lucilla Steinaa Tags: Research Source Type: research
A randomized clinical trial investigating the impact of magnesium supplementation on clinical and biochemical measures in COVID-19 patients
This study sought to examine the impact of magnesium supplementation on clinical outcomes and biochemical factors among hospitalized patients with COVID-19. (Source: Virology Journal)
Source: Virology Journal - April 23, 2024 Category: Virology Authors: Sepideh Rostami, Seyed Mohammad Alavi, Robab Daghagheleh, Elham Maraghi and Seyed Ahmad Hosseini Tags: Research Source Type: research
Effect of S-region mutations on HBsAg in HBsAg-negative HBV-infected patients
Occult HBV infection (OBI) is a special form of hepatitis B virus (HBV) infection that may cause Liver cirrhosis and hepatocellular carcinoma, causing significant harm to patients. Given the insidious nature o... (Source: Virology Journal)
Source: Virology Journal - April 23, 2024 Category: Virology Authors: Hui Liu, Shuxiang Chen, Xin Liu and Jinli Lou Tags: Research Source Type: research
Nonlinear relationship between viral load and TCT in single/multiple HPV52 infection
To determine the correlation between HPV (human papillomavirus) 52 viral load, multiple infections and ThinPrep cytology test (TCT), to inform clinical management of HPV52-positive women after cervical cancer ... (Source: Virology Journal)
Source: Virology Journal - April 23, 2024 Category: Virology Authors: Bingbing Ma, Jie Zhou, Weijuan Zhou, Zhanzhong Ma, Juan Chen and Hongbo Hu Tags: Research Source Type: research
Computational analysis of affinity dynamics between the variants of SARS-CoV-2 spike protein (RBD) and human ACE-2 receptor
The novel coronavirus SARS-CoV-2 resulted in a significant worldwide health emergency known as the COVID-19 pandemic. This crisis has been marked by the widespread of various variants, with certain ones causin... (Source: Virology Journal)
Source: Virology Journal - April 19, 2024 Category: Virology Authors: Nishad Sultana, S. N. Nagesha, C. N. Lakshminarayana Reddy, B. N. Ramesh, S. Shyamalamma, K. S. Shashidhara, K. M. Satish, C. Pradeep and G. D Vidyadhar Tags: Research Source Type: research
MST1/2 exerts a pivotal role in inducing neuroinflammation and Coxsackievirus-A10 replication by interacting with innate immunity
Coxsackievirus-A10 (CV-A10), responsible for the hand, foot and mouth disease (HFMD) pandemic, could cause serious central nervous system (CNS) complications. The underlying molecular basis of CV-A10 and host ... (Source: Virology Journal)
Source: Virology Journal - April 19, 2024 Category: Virology Authors: Yajie Hu, Minigmei Zhong, Yaming Lv, Wei Zhao, Baojiang Qian, Jie Song and Yunhui Zhang Tags: Research Source Type: research
Stability and integrity of self-assembled bovine parvovirus virus ‑like particles (BPV‑VLPs) of VP2 and combination of VP1VP2 assisted by baculovirus-insect cell expression: a potential logistical platform for vaccine deployment
Bovine parvovirus (BPV) is an autonomous DNA virus with a smaller molecular size and subtle differences in its structural proteins, unlike other animal parvoviruses. More importantly, this virus has the potent... (Source: Virology Journal)
Source: Virology Journal - April 19, 2024 Category: Virology Authors: Ashenafi Kiros Wubshet, Guo-xiu Li, Qian Li, Jun-Fei Dai, Yao-Zhong Ding, Luoyi Zhou, Min Qu, Yang Wang, Zhongyuan Ma, Gebremeskel Mamu Werid, Birhanu Hadush Abera, Asmelash Tassew Kebede, Yuefeng Sun, Xiangping Yin, Yongsheng Liu and Zhang Jie Tags: Methodology Source Type: research
Deciphering the virome of Chunkung (Cnidium officinale) showing dwarfism-like symptoms via a high-throughput sequencing analysis
Viruses have notable effects on agroecosystems, wherein they can adversely affect plant health and cause problems (e.g., increased biosecurity risks and economic losses). However, our knowledge of their divers... (Source: Virology Journal)
Source: Virology Journal - April 15, 2024 Category: Virology Authors: Mesele Tilahun Belete, Se Eun Kim, Workitu Firmosa Gudeta, Davaajargal Igori, Jeong A. Kwon, Su-Heon Lee and Jae Sun Moon Tags: Research Source Type: research
Immunopathological investigation and genetic evolution of Avian leukosis virus Subgroup-J associated with myelocytomatosis in broiler flocks in Egypt
Avian leukosis virus Subgroup-J (ALV-J) is a rapidly oncogenic evolving retrovirus infecting a variety of avian species; causing severe economic losses to the local poultry industry. (Source: Virology Journal)
Source: Virology Journal - April 10, 2024 Category: Virology Authors: Ahmed Fotouh, Eman Abd El-Menamm Shosha, Ali Mahmood Zanaty and Marwa Mostafa Darwesh Tags: Research Source Type: research
Recombination analysis on the receptor switching event of MERS-CoV and its close relatives: implications for the emergence of MERS-CoV
PlMERS-CoV is a coronavirus known to cause severe disease in humans, taxonomically classified under the subgenus Merbecovirus. Recent findings showed that the close relatives of MERS-CoV infecting vespertillionid... (Source: Virology Journal)
Source: Virology Journal - April 10, 2024 Category: Virology Authors: Jarel Elgin Tolentino, Spyros Lytras, Jumpei Ito and Kei Sato Tags: Research Source Type: research
