Hypoxia-inducible factor-1 α in myocardial infarction
World J Cardiol. 2024 Apr 26;16(4):181-185. doi: 10.4330/wjc.v16.i4.181.ABSTRACTHypoxia-inducible factor 1 (HIF1) has a crucial function in the regulation of oxygen levels in mammalian cells, especially under hypoxic conditions. Its importance in cardiovascular diseases, particularly in cardiac ischemia, is because of its ability to alleviate cardiac dysfunction. The oxygen-responsive subunit, HIF1α, plays a crucial role in this process, as it has been shown to have cardioprotective effects in myocardial infarction through regulating the expression of genes affecting cellular survival, angiogenesis, and metabolism. Furthe...
Source: World Journal of Cardiology - May 1, 2024 Category: Cardiology Authors: Ivana Škrlec Sergey N Kolomeichuk Source Type: research
Challenging situation of coronary artery anomaly associated with ischemia and/or risk of sudden death
World J Cardiol. 2024 Apr 26;16(4):173-176. doi: 10.4330/wjc.v16.i4.173.ABSTRACTCoronary artery anomaly is known as one of the causes of angina pectoris and sudden death and is an important clinical entity that cannot be overlooked. The incidence of coronary artery anomalies is as low as 1%-2% of the general population, even when the various types are combined. Coronary anomalies are practically challenging when the left and right coronary ostium are not found around their normal positions during coronary angiography with a catheter. If there is atherosclerotic stenosis of the coronary artery with an anomaly and percutaneo...
Source: World Journal of Cardiology - May 1, 2024 Category: Cardiology Authors: Shigenori Ito Source Type: research
Aspirin interruption before neurosurgical interventions: A controversial problem
World J Cardiol. 2024 Apr 26;16(4):191-198. doi: 10.4330/wjc.v16.i4.191.ABSTRACTAspirin is widely used for primary or secondary prevention of ischemic events. At the same time, chronic aspirin consumption can affect blood clot formation during surgical intervention and increase intraoperative blood loss. This is especially important for high-risk surgery, including neurosurgery. Current European Society of Cardiology guidelines recommend aspirin interruption for at least 7 d before neurosurgical intervention, but this suggestion is not supported by clinical evidence. This narrative review presents evidence that challenges ...
Source: World Journal of Cardiology - May 1, 2024 Category: Cardiology Authors: Alexander Kulikov Anton Konovalov Pier Paolo Pugnaloni Federico Bilotta Source Type: research
Left bundle branch pacing set to outshine biventricular pacing for cardiac resynchronization therapy?
World J Cardiol. 2024 Apr 26;16(4):186-190. doi: 10.4330/wjc.v16.i4.186.ABSTRACTThe deleterious effects of long-term right ventricular pacing necessitated the search for alternative pacing sites which could prevent or alleviate pacing-induced cardiomyopathy. Until recently, biventricular pacing (BiVP) was the only modality which could mitigate or prevent pacing induced dysfunction. Further, BiVP could resynchronize the baseline electromechanical dssynchrony in heart failure and improve outcomes. However, the high non-response rate of around 20%-30% remains a major limitation. This non-response has been largely attributable...
Source: World Journal of Cardiology - May 1, 2024 Category: Cardiology Authors: Akash Batta Juniali Hatwal Source Type: research
Correction: Establishment of a prediction model for prehospital return of spontaneous circulation in out-of-hospital patients with cardiac arrest
World J Cardiol. 2024 Apr 26;16(4):215-216. doi: 10.4330/wjc.v16.i4.215.ABSTRACT[This corrects the article on p. 508 in vol. 15, PMID: 37900904.].PMID:38690216 | PMC:PMC11056875 | DOI:10.4330/wjc.v16.i4.215 (Source: World Journal of Cardiology)
Source: World Journal of Cardiology - May 1, 2024 Category: Cardiology Authors: Jing-Jing Wang Qiang Zhou Zhen-Hua Huang Yong Han Chong-Zhen Qin Zhong-Qing Chen Xiao-Yong Xiao Zhe Deng Source Type: research
Transcatheter aortic valve replacement in low-risk young population: A double edge sword?
World J Cardiol. 2024 Apr 26;16(4):177-180. doi: 10.4330/wjc.v16.i4.177.ABSTRACTSince the advent of transcatheter aortic valve replacement (TAVR) in 2002, it has now become the default interventional strategy for symptomatic patients presenting with severe aortic stenosis, particularly in intermediate to high-surgical risk patients. In 2019, the United States Food and Drug Administration approved TAVR in low-risk patients based on two randomized trials. However, these breakthrough trials excluded patients with certain unfavorable anatomies and odd profiles. While currently there is no randomized study of TAVR in young pati...
Source: World Journal of Cardiology - May 1, 2024 Category: Cardiology Authors: Sukhdeep Bhogal Akash Batta Source Type: research
The cardiovascular system at high altitude: A bibliometric and visualization analysis
CONCLUSION: Over the past 32 years, research on the cardiovascular system in high-altitude regions has been steadily increasing. Future research in this field may focus on areas such as hypoxia adaptation, metabolism, and cardiopulmonary exercise. Strengthening interdisciplinary and multi-team collaborations will facilitate further exploration of the pathophysiological mechanisms underlying cardiovascular changes in high-altitude environments and provide a theoretical basis for standardized disease diagnosis and treatment.PMID:38690218 | PMC:PMC11056872 | DOI:10.4330/wjc.v16.i4.199 (Source: World Journal of Cardiology)
Source: World Journal of Cardiology - May 1, 2024 Category: Cardiology Authors: Mao-Lin Zhao Zhong-Jie Lu Li Yang Sheng Ding Feng Gao Yuan-Zhang Liu Xue-Lin Yang Xia Li Si-Yi He Source Type: research
Pacemaker post transcatheter aortic valve replacement: A multifactorial risk?
World J Cardiol. 2024 Apr 26;16(4):168-172. doi: 10.4330/wjc.v16.i4.168.ABSTRACTPacemaker post-transcatheter aortic valve replacement is related to multifactorial risk. Nwaedozie et al brought to the body of evidence electrocardiogram and clinical findings. However, procedural characteristics have at least as much impact on the final need for a permanent pacemaker and potentially on the pacing rate. In this regard, long-term follow-up and understanding of the impact of long-term stimulation is of utmost importance.PMID:38690219 | PMC:PMC11056876 | DOI:10.4330/wjc.v16.i4.168 (Source: World Journal of Cardiology)
Source: World Journal of Cardiology - May 1, 2024 Category: Cardiology Authors: Stephane Noble Karim Bendjelid Source Type: research
Hypoxia-inducible factor-1 α in myocardial infarction
World J Cardiol. 2024 Apr 26;16(4):181-185. doi: 10.4330/wjc.v16.i4.181.ABSTRACTHypoxia-inducible factor 1 (HIF1) has a crucial function in the regulation of oxygen levels in mammalian cells, especially under hypoxic conditions. Its importance in cardiovascular diseases, particularly in cardiac ischemia, is because of its ability to alleviate cardiac dysfunction. The oxygen-responsive subunit, HIF1α, plays a crucial role in this process, as it has been shown to have cardioprotective effects in myocardial infarction through regulating the expression of genes affecting cellular survival, angiogenesis, and metabolism. Furthe...
Source: World Journal of Cardiology - May 1, 2024 Category: Cardiology Authors: Ivana Škrlec Sergey N Kolomeichuk Source Type: research
Challenging situation of coronary artery anomaly associated with ischemia and/or risk of sudden death
World J Cardiol. 2024 Apr 26;16(4):173-176. doi: 10.4330/wjc.v16.i4.173.ABSTRACTCoronary artery anomaly is known as one of the causes of angina pectoris and sudden death and is an important clinical entity that cannot be overlooked. The incidence of coronary artery anomalies is as low as 1%-2% of the general population, even when the various types are combined. Coronary anomalies are practically challenging when the left and right coronary ostium are not found around their normal positions during coronary angiography with a catheter. If there is atherosclerotic stenosis of the coronary artery with an anomaly and percutaneo...
Source: World Journal of Cardiology - May 1, 2024 Category: Cardiology Authors: Shigenori Ito Source Type: research
Aspirin interruption before neurosurgical interventions: A controversial problem
World J Cardiol. 2024 Apr 26;16(4):191-198. doi: 10.4330/wjc.v16.i4.191.ABSTRACTAspirin is widely used for primary or secondary prevention of ischemic events. At the same time, chronic aspirin consumption can affect blood clot formation during surgical intervention and increase intraoperative blood loss. This is especially important for high-risk surgery, including neurosurgery. Current European Society of Cardiology guidelines recommend aspirin interruption for at least 7 d before neurosurgical intervention, but this suggestion is not supported by clinical evidence. This narrative review presents evidence that challenges ...
Source: World Journal of Cardiology - May 1, 2024 Category: Cardiology Authors: Alexander Kulikov Anton Konovalov Pier Paolo Pugnaloni Federico Bilotta Source Type: research
Left bundle branch pacing set to outshine biventricular pacing for cardiac resynchronization therapy?
World J Cardiol. 2024 Apr 26;16(4):186-190. doi: 10.4330/wjc.v16.i4.186.ABSTRACTThe deleterious effects of long-term right ventricular pacing necessitated the search for alternative pacing sites which could prevent or alleviate pacing-induced cardiomyopathy. Until recently, biventricular pacing (BiVP) was the only modality which could mitigate or prevent pacing induced dysfunction. Further, BiVP could resynchronize the baseline electromechanical dssynchrony in heart failure and improve outcomes. However, the high non-response rate of around 20%-30% remains a major limitation. This non-response has been largely attributable...
Source: World Journal of Cardiology - May 1, 2024 Category: Cardiology Authors: Akash Batta Juniali Hatwal Source Type: research
Correction: Establishment of a prediction model for prehospital return of spontaneous circulation in out-of-hospital patients with cardiac arrest
World J Cardiol. 2024 Apr 26;16(4):215-216. doi: 10.4330/wjc.v16.i4.215.ABSTRACT[This corrects the article on p. 508 in vol. 15, PMID: 37900904.].PMID:38690216 | PMC:PMC11056875 | DOI:10.4330/wjc.v16.i4.215 (Source: World Journal of Cardiology)
Source: World Journal of Cardiology - May 1, 2024 Category: Cardiology Authors: Jing-Jing Wang Qiang Zhou Zhen-Hua Huang Yong Han Chong-Zhen Qin Zhong-Qing Chen Xiao-Yong Xiao Zhe Deng Source Type: research
Transcatheter aortic valve replacement in low-risk young population: A double edge sword?
World J Cardiol. 2024 Apr 26;16(4):177-180. doi: 10.4330/wjc.v16.i4.177.ABSTRACTSince the advent of transcatheter aortic valve replacement (TAVR) in 2002, it has now become the default interventional strategy for symptomatic patients presenting with severe aortic stenosis, particularly in intermediate to high-surgical risk patients. In 2019, the United States Food and Drug Administration approved TAVR in low-risk patients based on two randomized trials. However, these breakthrough trials excluded patients with certain unfavorable anatomies and odd profiles. While currently there is no randomized study of TAVR in young pati...
Source: World Journal of Cardiology - May 1, 2024 Category: Cardiology Authors: Sukhdeep Bhogal Akash Batta Source Type: research
The cardiovascular system at high altitude: A bibliometric and visualization analysis
CONCLUSION: Over the past 32 years, research on the cardiovascular system in high-altitude regions has been steadily increasing. Future research in this field may focus on areas such as hypoxia adaptation, metabolism, and cardiopulmonary exercise. Strengthening interdisciplinary and multi-team collaborations will facilitate further exploration of the pathophysiological mechanisms underlying cardiovascular changes in high-altitude environments and provide a theoretical basis for standardized disease diagnosis and treatment.PMID:38690218 | PMC:PMC11056872 | DOI:10.4330/wjc.v16.i4.199 (Source: World Journal of Cardiology)
Source: World Journal of Cardiology - May 1, 2024 Category: Cardiology Authors: Mao-Lin Zhao Zhong-Jie Lu Li Yang Sheng Ding Feng Gao Yuan-Zhang Liu Xue-Lin Yang Xia Li Si-Yi He Source Type: research
