Ability of < em > Helicobacter pylori < /em > to internalize into < em > Candida < /em >
World J Gastroenterol. 2024 Apr 28;30(16):2281-2284. doi: 10.3748/wjg.v30.i16.2281.ABSTRACTThe following are our views regarding the "letter to the editor" (Helicobacter is preserved in yeast vacuoles! Does Koch's postulates confirm it?) by Alipour and Gaeini, and the response "letter to the editor" (Candida accommodates non-culturable Helicobacter pylori in its vacuole-Koch's postulates aren't applicable) by Siavoshi and Saniee. Alipour and Gaeini rejected the methods, results, discussion, and conclusions summarized in a review article by Siavoshi and Saniee. The present article reviews and discusses evidence on the evolu...
Source: World Journal of Gastroenterology - May 1, 2024 Category: Gastroenterology Authors: Zheng-Hong Chen Jian-Chao Sun Ting-Xiu Yang Gu-Zhen Cui Source Type: research

Drug-induced mucosal alterations observed during esophagogastroduodenoscopy
World J Gastroenterol. 2024 Apr 28;30(16):2220-2232. doi: 10.3748/wjg.v30.i16.2220.ABSTRACTSeveral features of drug-induced mucosal alterations have been observed in the upper gastrointestinal tract, i.e., the esophagus, stomach, and duodenum. These include pill-induced esophagitis, desquamative esophagitis, worsening of gastroesophageal reflux, chemotherapy-induced esophagitis, proton pump inhibitor-induced gastric mucosal changes, medication-induced gastric erosions and ulcers, pseudomelanosis of the stomach, olmesartan-related gastric mucosal inflammation, lanthanum deposition in the stomach, zinc acetate hydrate tablet...
Source: World Journal of Gastroenterology - May 1, 2024 Category: Gastroenterology Authors: Masaya Iwamuro Seiji Kawano Motoyuki Otsuka Source Type: research

Fecal microbiota transplantation for irritable bowel syndrome: Current evidence and perspectives
World J Gastroenterol. 2024 Apr 28;30(16):2179-2183. doi: 10.3748/wjg.v30.i16.2179.ABSTRACTIn this editorial we comment on the article published in the recent issue of the World journal of Gastroenterology. We focus specifically on the mechanisms un-derlying the effects of fecal microbiota transplantation (FMT) for irritable bowel syndrome (IBS), the factors which affect the outcomes of FMT in IBS patients, and challenges. FMT has emerged as a efficacious intervention for clostridium difficile infection and holds promise as a therapeutic modality for IBS. The utilization of FMT in the treatment of IBS has undergone scrutin...
Source: World Journal of Gastroenterology - May 1, 2024 Category: Gastroenterology Authors: Cong Dai Yu-Hong Huang Min Jiang Source Type: research

Transjugular intrahepatic portosystemic shunt: A promising therapy for recompensation in cirrhotic patients
World J Gastroenterol. 2024 Apr 28;30(16):2285-2286. doi: 10.3748/wjg.v30.i16.2285.ABSTRACTThis is a retrospective study focused on recompensation after transjugular intrahepatic portosystemic shunt (TIPS) procedure. The authors confirmed TIPS could be a treatment for recompensation of patients with cirrhosis according to Baveno VII. The paper identified age and post-TIPS portal pressure gradient as independent predictors of recompensation in patients with decompensated cirrhosis after TIPS. These results need to be validated in a larger prospective cohort.PMID:38690019 | PMC:PMC11056914 | DOI:10.3748/wjg.v30.i16.2285 (Sou...
Source: World Journal of Gastroenterology - May 1, 2024 Category: Gastroenterology Authors: Ya-Ni Jin Wei Zhang Source Type: research

MicroRNAs in inflammatory bowel disease: What do we know and what can we expect?
World J Gastroenterol. 2024 Apr 28;30(16):2184-2190. doi: 10.3748/wjg.v30.i16.2184.ABSTRACTMicroRNAs (miRNAs), small non-coding RNAs composed of 18-24 nucleotides, are potent regulators of gene expression, contributing to the regulation of more than 30% of protein-coding genes. Considering that miRNAs are regulators of inflammatory pathways and the differentiation of intestinal epithelial cells, there is an interest in exploring their importance in inflammatory bowel disease (IBD). IBD is a chronic and multifactorial disease of the gastrointestinal tract; the main forms are Crohn's disease and ulcerative colitis. Several s...
Source: World Journal of Gastroenterology - May 1, 2024 Category: Gastroenterology Authors: Ellen Cristina Souza de Oliveira Ana Elisa Valencise Quaglio Thais Gagno Grillo Luiz Claudio Di Stasi Ligia Yukie Sassaki Source Type: research

Optimization of tracheoesophageal fistula model established with T-shaped magnet system based on magnetic compression technique
CONCLUSION: Use of the modified T-shaped magnet scheme is safe and feasible for establishing TEF and can achieve a more stable and uniform fistula size compared with ordinary magnets. Most importantly, this model offers better controllability, which improves the flexibility of follow-up studies.PMID:38690021 | PMC:PMC11056911 | DOI:10.3748/wjg.v30.i16.2272 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - May 1, 2024 Category: Gastroenterology Authors: Miao-Miao Zhang Jian-Qi Mao Lin-Xin Shen Ai-Hua Shi Xin Lyu Jia Ma Yi Lyu Xiao-Peng Yan Source Type: research

Laryngopharyngeal reflux disease: Updated examination of mechanisms, pathophysiology, treatment, and association with gastroesophageal reflux disease
World J Gastroenterol. 2024 Apr 28;30(16):2209-2219. doi: 10.3748/wjg.v30.i16.2209.ABSTRACTLaryngopharyngeal reflux disease (LPRD) is an inflammatory condition in the laryngopharynx and upper aerodigestive tract mucosa caused by reflux of stomach contents beyond the esophagus. LPRD commonly presents with sym-ptoms such as hoarseness, cough, sore throat, a feeling of throat obstruction, excessive throat mucus. This complex condition is thought to involve both reflux and reflex mechanisms, but a clear understanding of its molecular mechanisms is still lacking. Currently, there is no standardized diagnosis or treatment protoc...
Source: World Journal of Gastroenterology - May 1, 2024 Category: Gastroenterology Authors: Na Cui Ting Dai Yang Liu Ya-Yu Wang Jia-Yu Lin Qing-Fan Zheng Dong-Dong Zhu Xue-Wei Zhu Source Type: research

Chitin-glucan improves important pathophysiological features of irritable bowel syndrome
CONCLUSION: CG decreased visceral perception and intestinal inflammation through master gene regulation and direct binding of microbial products, suggesting that CG may constitute a new therapeutic strategy for patients with IBS or IBS-like symptoms.PMID:38690023 | PMC:PMC11056916 | DOI:10.3748/wjg.v30.i16.2258 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - May 1, 2024 Category: Gastroenterology Authors: Caroline Valibouze Caroline Dubuquoy Philippe Chavatte Micha ël Genin Veronique Maquet Salvatore Modica Pierre Desreumaux Christel Rousseaux Source Type: research

Mechanisms of tumor immunosuppressive microenvironment formation in esophageal cancer
World J Gastroenterol. 2024 Apr 28;30(16):2195-2208. doi: 10.3748/wjg.v30.i16.2195.ABSTRACTAs a highly invasive malignancy, esophageal cancer (EC) is a global health issue, and was the eighth most prevalent cancer and the sixth leading cause of cancer-related death worldwide in 2020. Due to its highly immunogenic nature, emer-ging immunotherapy approaches, such as immune checkpoint blockade, have demonstrated promising efficacy in treating EC; however, certain limitations and challenges still exist. In addition, tumors may exhibit primary or acquired resistance to immunotherapy in the tumor immune microenvironment (TIME); ...
Source: World Journal of Gastroenterology - May 1, 2024 Category: Gastroenterology Authors: Xiao-Jun Zhang Yan Yu He-Ping Zhao Lei Guo Kun Dai Jing Lv Source Type: research

Association between childhood obesity and gut microbiota: 16S rRNA gene sequencing-based cohort study
CONCLUSION: Obese children exhibited lower α-diversity in their gut microbiota than did the normal-weight children. Significant differences were observed in the composition of gut microbiota between obese and normal-weight children.PMID:38690025 | PMC:PMC11056921 | DOI:10.3748/wjg.v30.i16.2249 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - May 1, 2024 Category: Gastroenterology Authors: Xu-Ming Li Qing Lv Ya-Jun Chen Lu-Biao Yan Xin Xiong Source Type: research

Microplastics and microbiota: Unraveling the hidden environmental challenge
World J Gastroenterol. 2024 Apr 28;30(16):2191-2194. doi: 10.3748/wjg.v30.i16.2191.ABSTRACTThis editorial explores the intricate relationship between microplastics (MPs) and gut microbiota, emphasizing the complexity and environmental health implications. The gut microbiota, a crucial component of gastrointestinal health, is examined in the context of potential microbial degradation of MPs. Furthermore, dysbiosis induced by MPs emerges as a consensus, disrupting the balance of gut microbiota and decreasing diversity. The mechanisms triggering dysbiosis, including physical interactions and chemical composition, are under in...
Source: World Journal of Gastroenterology - May 1, 2024 Category: Gastroenterology Authors: Jean Demarquoy Source Type: research

Preoperative prediction of perineural invasion of rectal cancer based on a magnetic resonance imaging radiomics model: A dual-center study
CONCLUSION: The CR model based on preoperative MRI radiomics features and clinical risk factors can preoperatively predict the PNI status of RC noninvasively, which facilitates individualized treatment of RC patients.PMID:38690027 | PMC:PMC11056922 | DOI:10.3748/wjg.v30.i16.2233 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - May 1, 2024 Category: Gastroenterology Authors: Yan Liu Bai-Jin-Tao Sun Chuan Zhang Bing Li Xiao-Xuan Yu Yong Du Source Type: research

Ability of < em > Helicobacter pylori < /em > to internalize into < em > Candida < /em >
World J Gastroenterol. 2024 Apr 28;30(16):2281-2284. doi: 10.3748/wjg.v30.i16.2281.ABSTRACTThe following are our views regarding the "letter to the editor" (Helicobacter is preserved in yeast vacuoles! Does Koch's postulates confirm it?) by Alipour and Gaeini, and the response "letter to the editor" (Candida accommodates non-culturable Helicobacter pylori in its vacuole-Koch's postulates aren't applicable) by Siavoshi and Saniee. Alipour and Gaeini rejected the methods, results, discussion, and conclusions summarized in a review article by Siavoshi and Saniee. The present article reviews and discusses evidence on the evolu...
Source: World Journal of Gastroenterology - May 1, 2024 Category: Gastroenterology Authors: Zheng-Hong Chen Jian-Chao Sun Ting-Xiu Yang Gu-Zhen Cui Source Type: research

Drug-induced mucosal alterations observed during esophagogastroduodenoscopy
World J Gastroenterol. 2024 Apr 28;30(16):2220-2232. doi: 10.3748/wjg.v30.i16.2220.ABSTRACTSeveral features of drug-induced mucosal alterations have been observed in the upper gastrointestinal tract, i.e., the esophagus, stomach, and duodenum. These include pill-induced esophagitis, desquamative esophagitis, worsening of gastroesophageal reflux, chemotherapy-induced esophagitis, proton pump inhibitor-induced gastric mucosal changes, medication-induced gastric erosions and ulcers, pseudomelanosis of the stomach, olmesartan-related gastric mucosal inflammation, lanthanum deposition in the stomach, zinc acetate hydrate tablet...
Source: World Journal of Gastroenterology - May 1, 2024 Category: Gastroenterology Authors: Masaya Iwamuro Seiji Kawano Motoyuki Otsuka Source Type: research

Fecal microbiota transplantation for irritable bowel syndrome: Current evidence and perspectives
World J Gastroenterol. 2024 Apr 28;30(16):2179-2183. doi: 10.3748/wjg.v30.i16.2179.ABSTRACTIn this editorial we comment on the article published in the recent issue of the World journal of Gastroenterology. We focus specifically on the mechanisms un-derlying the effects of fecal microbiota transplantation (FMT) for irritable bowel syndrome (IBS), the factors which affect the outcomes of FMT in IBS patients, and challenges. FMT has emerged as a efficacious intervention for clostridium difficile infection and holds promise as a therapeutic modality for IBS. The utilization of FMT in the treatment of IBS has undergone scrutin...
Source: World Journal of Gastroenterology - May 1, 2024 Category: Gastroenterology Authors: Cong Dai Yu-Hong Huang Min Jiang Source Type: research