Subject: Infusion of hypertonic saline/starch during cardiopulmonary bypass reduces fluid overload and may impact cardiac function

Infusion of hypertonic saline/starch during cardiopulmonary bypass reduces fluid overload and may impact cardiac functionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study aimed to confirm an improvement of cardiopulmonary function by reducing fluid loading during an open-heart surgery. Forty-nine elective CABG patients were randomized to an intraoperative infusion of hypertonic saline/hydroxyethyl starch (HSH group) or Ringer's solution (CT group). Both groups received 1 ml/kg/h of the study solution for 4 h after baseline values were obtained (PICCO® transpulmonary thermodilution technique). Net fluid balance (NFB), hemodynamic and laboratory parameters were measured. NFB was four times higher in the CT group compared with the HSH group during the first 6 h post-operatively. Th...
Source: Acta Anaesthesiologica Scandinavica - October 30, 2009 Category: Anesthesiology Authors: V. L. KVALHEIM, M. FARSTAD, E. STEIEN, A. MONGSTAD, B. A. BORGE, P. M. KVITTING, P. HUSBY Source Type: journals