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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 23.

Production of Antibody Fragments in Escherichia coli
Escherichia coli is a host widely used in the industrial production of recombinant proteins. However, the expression of heterologous proteins in E. coli often encounters the formation of inclusion bodies, which are insoluble and nonfunctional protein aggregates. For the successful production of antibody fragments, which includes single-chain variable fragments (scFvs), we describe here the modification of linker, signal, and Shine–Dalgarno (SD) sequences, the coexpression of cytoplasmic and periplasmic chaperones, and a method for fed-batch cultivation with exponential feed.
Source: Springer protocols feed by Immunology - August 21, 2012 Category: Allergy & Immunology Source Type: news

Mammalian Cell Surface Display of Full Length IgG
Display technology has been developed and widely used in antibody screening and selecting. While phage can only display antibody fragments, mammalian cells can display not only fragments but full-length antibodies. Here we described the display of full length antibody on the surface of 293 cells. Both heavy chain and light chain genes were cloned in a single mammalian expression vector containing dual mammalian expression cassettes. While transfected into 293 cells of the vector, both heavy and light chains were expressed. With the help of transmembrane domain of platelet-derived growth factor receptor (PDGFR-TM) fused at ...
Source: Springer protocols feed by Immunology - August 21, 2012 Category: Allergy & Immunology Source Type: news

Evolution of Antibodies In Vitro by Ribosome Display
Ribosome display is a cell-free technology which enables in vitro selection and evolution of antibodies from very large diversified DNA libraries. It operates through the following key steps: (1) generation of PCR library; (2) formation of stable antibody-ribosome-mRNA (ARM) complexes as the selection particles, (3) selection of ligand-binding ARM complexes on an immobilized ligand and (4) recovery of the selected genetic information as DNA by RT-PCR. Since PCR-based random or/and site-directed mutagenesis can be easily used to introduce mutations into the selected DNA pool in each cycle, ribosome display offers an efficie...
Source: Springer protocols feed by Immunology - August 21, 2012 Category: Allergy & Immunology Source Type: news

Selection of Antibody Fragments by Yeast Display
The critical need for renewable, high-quality affinity reagents in biological research, as well as for diagnostic and therapeutic applications, has required the development of new platforms of discovery. Yeast display is one of the main methods of in vitro display technology with phage display. Yeast display has been chosen by numerous groups to refine both affinity and specificity of antibodies because it enables fine discrimination between mutant clones of similar affinity. In addition, the construction of display libraries of antibody fragments in yeast permit to sample the immune antibody repertoire more fully than usi...
Source: Springer protocols feed by Immunology - August 21, 2012 Category: Allergy & Immunology Source Type: news

Humanization by Guided Selections
Guided selection provides a powerful tool for humanization of the preexisting nonhuman antibodies as exemplified by HUMIRA, the world’s first human antibody approved. This chapter describes the sequential guided selection procedure in which mouse VL and VH domains are replaced sequentially with human VL and VH, respectively to derive completely human antibody. The detailed protocols for construction of phage-displayed antibody library, panning, screening, and characterization, are included to achieve successful selection of human antibody with similar characteristics to original mouse antibody.
Source: Springer protocols feed by Immunology - August 21, 2012 Category: Allergy & Immunology Source Type: news

Humanization by CDR Grafting and Specificity-Determining Residue Grafting
Humanized antibodies are constructed by CDR grafting, while retaining those murine framework residues that influence the antigen-binding activity. To reduce the immunogenicity of CDR-grafted humanized antibodies, the murine content in the CDR-grafted humanized antibodies is minimized through SDR grafting. Within each CDR, there are more variable positions that are directly involved in the interaction with antigen, i.e., specificity-determining residues (SDRs), whereas there are more conserved residues that maintain the conformations of CDRs loops. SDRs may be identified from the 3D structure of the antigen–antibody c...
Source: Springer protocols feed by Immunology - August 21, 2012 Category: Allergy & Immunology Source Type: news

Phage Display and Selections on Cells
We describe here a procedure of a panning strategy on cell surface receptors including a depletion step. We explain every step of the protocol: production of phage library, depletion and selection, elution, screening by ELISA, and analysis of soluble antibodies by ELISA and flow cytometry. Finally, several possible variants of the protocol are explained in Subheading 4.
Source: Springer protocols feed by Immunology - August 21, 2012 Category: Allergy & Immunology Source Type: news

Phage Display and Selections on Purified Antigens
The isolation of antibody fragments targeting proteins implicated in cancers and other diseases remains a crucial issue on targeted therapy or diagnostic tool development (Hoogenboom HR, Henderikx P, de Haard H. Adv Drug Deliv Rev 31 (1–2):5–31, 1998). In many case, the protein of interest, or a relevant portion of this protein such as its extracellular domain is available as purified protein. In such cases, phage display on purified antigen is an easy and fast way to select antibody fragment able to efficiently bind this antigen. However, the output of phage selection can vary significantly depending on the wa...
Source: Springer protocols feed by Immunology - August 21, 2012 Category: Allergy & Immunology Source Type: news

Generation and Isolation of Target-Specific Single-Domain Antibodies from Shark Immune Repertoires
The drive to exploit novel targets and biological pathways has lead to the expansion of classical antibody research into innovative fragment adaptations and novel scaffolds. The hope being that alternative or cryptic epitopes may be targeted, tissue inaccessibility may be overcome, and easier engineering options will facilitate multivalent, multi-targeting approaches. To this end, we have been isolating shark single domains to gain a greater understanding of their potential as therapeutic agents. Their unique shape, small size, inherent stability, and simple molecular architecture make them attractive candidates from a dru...
Source: Springer protocols feed by Immunology - August 21, 2012 Category: Allergy & Immunology Source Type: news

Generation of Single Domain Antibody Fragments Derived from Camelids and Generation of Manifold Constructs
Immunizing a camelid (camels and llamas) with soluble, properly folded proteins raises an affinity-matured immune response in the unique camelid heavy-chain only antibodies (HCAbs). The peripheral blood lymphocytes of the immunized animal are used to clone the antigen-binding antibody fragment from the HCAbs in a phage display vector. A representative aliquot of the library of these antigen-binding fragments is used to retrieve single domain antigen-specific binders by successive rounds of panning. These single domain antibody fragments are cloned in tandem to generate manifold constructs (bivalent, biparatopic or bispecif...
Source: Springer protocols feed by Immunology - August 21, 2012 Category: Allergy & Immunology Source Type: news

Selection of Stable scFv Antibodies by Phage Display
ScFv fragments are popular recombinant antibody formats but often suffer from limited stability. Phage display is a powerful tool in antibody engineering and applicable also for stability selection. ScFv variants with improved stability can be selected from large randomly mutated phage displayed libraries with a specific antigen after the unstable variants have been inactivated by heat or GdmCl. Irreversible scFv denaturation, which is a prerequisite for efficient selection, is achieved by combining denaturation with reduction of the intradomain disulfide bonds. Repeated selection cycles of increasing stringency result in ...
Source: Springer protocols feed by Immunology - August 21, 2012 Category: Allergy & Immunology Source Type: news

Synthetic Customized scFv Libraries
We describe here a simple protocol to make large and diverse libraries based on a single or few frameworks. Diversity is introduced in the third hypervariable loops using degenerate synthetic oligonucleotides and PCR assembly. Because all the antibody fragments isolated from the library will share their framework sequence, their stability and physical properties will be more consistent and customizable than when antibody fragments are isolated from a library prepared from human donors.
Source: Springer protocols feed by Immunology - August 21, 2012 Category: Allergy & Immunology Source Type: news

Construction of Human Naive Antibody Gene Libraries
Human antibodies are valuable tools for proteome research and diagnostics. Furthermore, antibodies are a rapidly growing class of therapeutic agents, mainly for inflammation and cancer therapy. The first therapeutic antibodies are of murine origin and were chimerized or humanized. The later-developed antibodies are fully human antibodies. Here, two technologies are competing the hybridoma technology using transgenic mice with human antibody gene loci and antibody phage display. The starting point for the selection of human antibodies against any target is the construction of an antibody phage display gene library.
Source: Springer protocols feed by Immunology - August 21, 2012 Category: Allergy & Immunology Source Type: news

Human In-Cell scFv Library from Infiltrating B Cell
The construction of a large library of single-chain Fv (scFv) antibody fragments involves a random assortment of heavy and light chains. Although useful for the production of recombinant antibodies, this method is not totally adapted to the study of the antibody repertoire formed in vivo during, for example, autoimmune diseases.
Source: Springer protocols feed by Immunology - August 21, 2012 Category: Allergy & Immunology Source Type: news

Cloning Single-Chain Antibody Fragments (ScFv) from Hyrbidoma Cells
Despite the rising impact of the generation of antibodies by phage display and other technologies, hybridoma technology still provides a valuable tool for the generation of high-affinity binders against different targets. But there exist several limitations of using hybridoma-derived antibodies. The source of the hybridoma clones are mostly rat or mouse B-lymphocytes. Therefore a human-anti-mouse or human-anti-rat antibody response may result in immunogenicity of these antibodies. This leads to the necessity of humanization of these antibodies where the knowledge of the amino acid sequence of the proteins is inalienable. F...
Source: Springer protocols feed by Immunology - August 21, 2012 Category: Allergy & Immunology Source Type: news

Generation of Human Single Domain Antibody Repertoires by Kunkel Mutagenesis
Human antibody single domains are a promising new class of antibody fragments. Here we describe methods for the cloning of human VH and VL genes into phage and phagemid vectors. Furthermore, we provide detailed protocols for the generation of single domain antibody libraries by Kunkel mutagenesis and the analysis of diversity by DNA sequencing and superantigen binding.
Source: Springer protocols feed by Immunology - August 21, 2012 Category: Allergy & Immunology Source Type: news

Computer-Assisted Modeling of Antibody Variable Domains
Antibody modeling is an interesting option to gain structure–function insights and to allow rational engineering of these molecules in the absence of experimental data. Among a diversity of algorithms, software packages, and specialized Web servers, the protocol described here presents the following main features: (1) nonautomatic modeling process guided by direct application of antibody modeling principles; (2) local generation of molecular models using free software which can be used in most common operational systems; and (3) the resulting model quality is comparable to models generated by Web servers which repres...
Source: Springer protocols feed by Immunology - August 21, 2012 Category: Allergy & Immunology Source Type: news

Use of IMGT® Databases and Tools for Antibody Engineering and Humanization
IMGT®, the international ImMunoGeneTics information system® (http://www.imgt.org), was created in 1989 to manage the huge diversity of the antigen receptors, immunoglobulins (IG) or antibodies, and T cell receptors (TR). Standardized sequence and structure analysis of antibody using IMGT® databases and tools allows one to bridge, for the first time, the gap between antibody sequences and three-dimensional (3D) structures. This is achieved through the IMGT Scientific chart rules, based on the IMGT-ONTOLOGY concepts of classification (IMGT gene and allele nomenclature), description (IMGT standardized labels), and...
Source: Springer protocols feed by Immunology - August 21, 2012 Category: Allergy & Immunology Source Type: news

MHRA warns against Echinacea use in under 12s
Children under 12 years old should not use oral herbal products containing Echinacea due to potential risks of severe allergic reactions, the Medicines and Healthcare products Regulatory Agency (MHRA) has warned read more
Source: Nursing in Practice - August 21, 2012 Category: Nursing Authors: lnaughton Tags: Children ' s health Editor s pick Source Type: news

NIH awards $7.8 million for innovative HIV vaccine approaches
The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has awarded 14 grants totaling $7.8 million in first-year funding for basic research to identify new approaches for designing a safe and effective HIV vaccine. The grants were awarded under the Innovation for HIV Vaccine Discovery (IHVD) initiative, which is expected to receive up to $34.8 million over the next four years.
Source: National Institutes of Health (NIH) News Releases - August 21, 2012 Category: American Health Source Type: news

Best of Medical Blogs - weekly review and blog carnival
The “Best of Medical Blogs - weekly review and blog carnival” is a weekly summary of the best posts from medical blogs. Feel free to send your suggestions to my email at clinicalcases@gmail.com. Best of Medical Blogs (BMB) is published every Tuesday, just like the old Grand Rounds. What is #FOAM? Free Open Access Meducation http://goo.gl/ILrMh EM and critical care physicians adopt social media at rapid pace Here is the remarkable growth just in the last 18 months: 77% Twitter, 42% Facebook and 20% for Google Plus. An increasing number of blogs (21%) now have multiple authors. There is better identification...
Source: Clinical Cases and Images - August 21, 2012 Category: Journals (General) Tags: Best of Medical Blogs Source Type: news

Skin Test-Guided Elimination Diets for Eosinophilic EsophagitisSkin Test-Guided Elimination Diets for Eosinophilic Esophagitis
Adults with eosinophilic esophagitis (EoE) may not get much benefit from eliminating food antigens from their diet based on skin testing, according to a new study. Reuters Health Information
Source: Medscape Allergy Headlines - August 21, 2012 Category: Allergy & Immunology Tags: Allergy & Clinical Immunology News Source Type: news

Echinacea allergy warning for children under 12
‘Echinacea remedy is not for children under 12’, BBC News reports, while the Daily Mail tells us that echinacea can ‘trigger allergies’ in kids. The news is based on a press release issued by the Medicines and Healthcare products Regulatory Agency (MHRA) advising parents and carers not to give oral herbal products containing echinacea to children younger than 12 years. The warning has been issued due to the risk of rare allergic reactions the MHRA says ‘may sometimes be severe’ in this age group. The MHRA says that licensed echinacea products that were registered for use in children aged 6 to 12 are having thei...
Source: NHS News Feed - August 21, 2012 Category: Consumer Health News Tags: QA articles Medication Source Type: news

NIH awards $7.8 million for innovative HIV vaccine approaches
(NIH/National Institute of Allergy and Infectious Diseases) NIAID has awarded 14 grants totaling $7.8 million in first-year funding for basic research to identify new approaches for designing a safe and effective HIV vaccine. The grants were awarded under the Innovation for HIV Vaccine Discovery initiative, which is expected to receive up to $34.8 million over the next four years.
Source: EurekAlert! - Medicine and Health - August 21, 2012 Category: Global & Universal Source Type: news

CDD, SRI receive NIAID grant to develop tuberculosis drug discovery computational tools
The National Institute of Allergy and Infectious Diseases (NIAID), a part of the National Institutes of Health, has issued Phase II small business technology transfer research (STTR) grant to Collaborative Drug Discovery (CDD) and SRI International t…
Source: Drug Development Technology - August 20, 2012 Category: Pharmaceuticals Source Type: news

Echinacea could trigger allergies in children under 12, warns UK drugs watchdog
A popular herbal remedy used to ward off colds should not be given to children under 12, according to the UK drugs watchdog.
Source: the Mail online | Health - August 20, 2012 Category: Consumer Health News Source Type: news

Qsymia and Belviq Drugs for Obesity, Weight Loss
If you’re obese and are at the end of your ropes looking for weight loss help, there’s good news from the U.S. Food and Drug Administration (FDA). The FDA in the past few months has approved two new weight loss drugs for people who struggle with obesity — Qsymia and Belviq. It should be noted up-front that these drugs are meant for people who are obese — those with a BMI number 30 or greater. While doctors often prescribe drugs for conditions not specifically approved by the FDA (called “off-label” use), doctors are likely to be more conservative in prescribing these two drugs when they...
Source: Psych Central - August 20, 2012 Category: Psychiatry Authors: John M. Grohol, Psy.D. Tags: Disorders Eating Disorders General Medications Miscellaneous Drugs Weight Loss Arena Pharmaceuticals Bmi Cholesterol Clinical Trials Effective Weight Loss Food And Drug Food And Drug Administration Food And Drug Administration Fd Source Type: news

Don't give children echinacea, warns MHRA
Parents should not give echinacea, the popular herbal remedy for coughs and colds, to children under 12 because of the risk of "severe" allergic reactions, the drugs regulator is warning.
Source: Telegraph Health - August 20, 2012 Category: Consumer Health News Tags: cough herbal medicine cold echinacea allergy Source Type: news

MHRA press release: Echinacea herbal products should not be used in children under 12 years old
Source: MHRA Area: News The Medicines and Healthcare products Regulatory Agency (MHRA) is advising parents and carers not to use oral herbal products containing Echinacea for children below 12 years of age.    This follows precautionary advice from the European Herbal Medicinal Products Committee (HMPC) and from the UK Herbal Medicines Advisory Committee (HMAC), who concluded that the perceived benefits of its use in this age group are outweighed by the potential risks.  There is a low risk of allergic reactions but these could be severe.    Risks of side effects in older children (aged ?1...
Source: NeLM - News - August 20, 2012 Category: Drugs & Pharmacology Source Type: news

What Causes Halitosis?
Discussion Halitosis or bad breath can be caused by a number of problems. The most common reason is retained food, cellular debris (epithelial cells) and bacteria (usually anaerobic) combining to cause problems in the mouth. These problems combined with decreased saliva (dehydration, mouth breathing, salivary gland disease, diabetes, chemotherapy, medications, etc.) and often poor dental hygiene are some of the most common reasons for halitosis. Other reasons can also include increased protein relative to carbohydrate in diet and the oral pH is more alkaline. The back of the tongue is the most common place for retained foo...
Source: PediatricEducation.org - August 19, 2012 Category: Pediatrics Authors: Donna M. D'Alessandro, M.D. Tags: Uncategorized Source Type: news

Podcast: Engineering living tissue
Dr Suwan Jayasinghe discusses his work at University College London, where his team is engineering at the cellular level to create tissues that will one day repair or replace whole organs.Dr Jayasinghe will be one of the speakers at the Electromagnetic Field festival, a science and tech camp that runs from Friday 31 August to Sunday 2 September at Pineham Park, Milton Keynes. Aleks Krotoski from our sister podcast Tech Weekly meets one of its founders, Jonty Wareing. Also on the show: Professor Polly Roy from the London School of Hygiene and Tropical Medicine talks about her decades working to build synthetic versions of t...
Source: Guardian Unlimited Science - August 19, 2012 Category: Science Authors: Alok Jha, Jason Phipps, Aleks Krotoski Tags: Tissue engineering Biology Infectious diseases guardian.co.uk Immunology Editorial Science Source Type: news

Malignant Brain Cancer Antigens Targeted By Vaccine Which Significantly Lengthens Survival
An experimental immune-based therapy more than doubled median survival of patients diagnosed with the most aggressive malignant brain tumor, Cedars-Sinai Medical Center researchers reported in Cancer Immunology, Immunotherapy, published online. Median survival in a Phase I clinical trial at Cedars-Sinai's Johnnie L. Cochran, Jr. Brain Tumor Center was 38.4 months, significantly longer than the typical 14.6-month survival of patients with newly diagnosed glioblastoma receiving standard therapy alone, which includes radiation and chemotherapy...
Source: Health News from Medical News Today - August 19, 2012 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news

Influenza Vaccination Schedule for Children UpdatedInfluenza Vaccination Schedule for Children Updated
New recommendations also provide information on the 2012-2013 vaccine strains and support use of the trivalent inactivated influenza vaccine in persons with mild egg allergies. Medscape Medical News
Source: Medscape Today Headlines - August 17, 2012 Category: Consumer Health News Tags: Pediatrics News Source Type: news

Video: Home changes can improve allergies
A new study shows renters are less likely to make indoor modifications to improve their allergies than homeowners. Dr. Holly Phillips reports.
Source: Health News: CBSNews.com - August 17, 2012 Category: Consumer Health News Source Type: news

Allergic Reaction to Strap on Personal Heart Rate Monitor in a Marathon Runner
This man wore a personal heart rate monitor/transmitter while running, and had become allergic to the thiuram chemicals used to make the synthetic elastic band.
Source: Consultant Live - August 17, 2012 Category: Primary Care Source Type: news

ALLERGY RELIEF D 12 (Loratadine, Pseudoephedrine) Tablet, Extended Release [CVS Pharmacy]
Updated Date: Aug 17, 2012 EST
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - August 17, 2012 Category: Drugs & Pharmacology Source Type: news

ALLERGY AND CONGESTION RELIEF (Loratadine, Pseudoephedrine) Tablet, Extended Release [Kroger Company]
Updated Date: Aug 17, 2012 EST
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - August 17, 2012 Category: Drugs & Pharmacology Source Type: news

Allergy transmission may be gender specific
Parents with allergies are more likely to pass them on to their same gender children than to children of the opposite gender, say researchers.
Source: MedWire News - Dermatology - August 16, 2012 Category: Dermatology Source Type: news

Single Domain Antibodies
Methods and Protocolsseries:Methods in Molecular BiologyThe development of the hybridoma technology created the possibility to obtain unlimited amounts of monoclonal antibodies (mAb) with high specificity and affinity for any target and to introduce mAbs in a wide range of applications; however, the bulky size of mAbs, costly production, and cumbersome engineering hampered regularly their streamlined development in some applications.  In Single ...
Source: Springer Biomedical Sciences titles - August 16, 2012 Category: Biomedical Science Tags: Immunology Source Type: news

Time for transition? We can help.
Kitty O'Hare, MD By Kitty O’Hare, MD, coordinator of Transition Medicine at Boston Children’s Hospital’s Martha Eliot Health Center. The field of pediatric medicine has come a long way in the past few decades. Kids with health conditions like sickle cell disease, heart conditions, even cancer are living, full, healthy lives into adulthood. It’s a great accomplishment, but with increased survival rates come unique challenges. In addition to treating their chronically ill patients, today’s pediatricians need to prepare them for adult life, where they will be responsible for managing their own h...
Source: Thrive, Children's Hospital Boston - August 16, 2012 Category: Pediatrics Authors: Guest Blogger Tags: All posts Parenting Teen health Frances O’Hare Medical transitioning Niraj Sharma Transitioning from Pediatric to Adult-Centered Medial Care Source Type: news

Schoolgirl, six, has such severe allergies she could be killed by a kiss and has to be wrapped in bandages 24 hours a day
Isla Frank's parents, from Stoke-on-Trent, even have to keep her clothes in a freezer instead of a wardrobe - because of her extreme reaction to dust mites.
Source: the Mail online | Health - August 15, 2012 Category: Consumer Health News Source Type: news

Auvi-Q™, First Voice-Guided Epinephrine Auto-Injector For Patients With Life-Threatening Allergies, Receives FDA Approval
Breakthrough device design talks patients and caregivers through the injection process Sanofi (EURONEXT: SAN and NYSE: SNY) have announced that the U.S. Food and Drug Administration (FDA) has approved Auvi-Q (epinephrine injection, USP) for the emergency treatment of life-threatening allergic reactions in people who are at risk for or have a history of anaphylaxis. Auvi-Q is the first-and-only compact epinephrine auto-injector with audio and visual cues that guide patients and caregivers step-by-step through the injection process...
Source: Health News from Medical News Today - August 15, 2012 Category: Consumer Health News Tags: Allergy Source Type: news

NIH study suggests potential hurdle to universal flu vaccine development may be overcome
(NIH/National Institute of Allergy and Infectious Diseases) In the quest for a universal influenza vaccine -- one that elicits broadly neutralizing antibodies that can protect against most or all strains of flu virus -- scientists have faced a sobering question: Does pre-existing immunity generated by prior exposure to influenza virus or vaccine hamper production of broadly neutralizing antibodies? If so, then a universal flu vaccine might work best (and perhaps only) in very young children who have had limited exposure to influenza viruses or vaccines.
Source: EurekAlert! - Infectious and Emerging Diseases - August 15, 2012 Category: Infectious Diseases Source Type: news

Study: Vaccine targets malignant brain cancer antigens, significantly lengthens survival
(Cedars-Sinai Medical Center) An experimental immune-based therapy more than doubled median survival of patients diagnosed with the most aggressive malignant brain tumor, Cedars-Sinai Medical Center researchers reported in Cancer Immunology, Immunotherapy.
Source: EurekAlert! - Medicine and Health - August 15, 2012 Category: Global & Universal Source Type: news

Hummingbird Wholesale Issues Allergy Alert On Undeclared Peanuts In Organic Pinenuts
Hummingbird Wholesale of Eugene, OR is alerting consumers who purchased Organic Bulk Pinenuts from Natural Food Retail stores between 3/22/2012 and 8/16/2012 that these bulk pinenuts may contain undeclared peanuts.
Source: Food and Drug Administration - August 14, 2012 Category: Food Science Source Type: news

Should Young Men Be Vaccinated Against Human Papilloma Virus?
A new study published in Viral Immunology has sparked a debate on whether the human papilloma virus (HPV) vaccination should be given to men. The review - available at http://www.liebertpub.com/vim - was conducted by Gorren Low and colleagues from University of Southern California and David Geffen School of Medicine, Los Angeles, CA, and Georgetown University School of Medicine, Washington, DC. The researchers assessed how cost effective it is to expand routine HPV vaccination to include young males as well as the potential for reducing illness caused by HPV infection...
Source: Health News from Medical News Today - August 14, 2012 Category: Consumer Health News Tags: Cervical Cancer / HPV Vaccine Source Type: news

Almond Allergy Alert and Voluntary Recall of a Limited Number of Mislabeled Blueberry Crisp CLIF® Bars
Clif Bar & Company is initiating a voluntary recall today of a small amount of 12-pack Blueberry Crisp CLIF® Bars and individual mislabeled Blueberry Crisp CLIF Bars in Chocolate Chip CLIF Bar Wrappers with one "Best By" date 17MAR13G3 that were distributed to a limited number of stores predominately east of the Mississippi. The 12-packs may contain Blueberry Crisp CLIF Bars that are mislabeled with Chocolate Chip CLIF Bar wrappers and do not list almonds in the ingredient statement. Clif is taking this precautionary safety step for people who are allergic to almonds.
Source: Food and Drug Administration - August 14, 2012 Category: Food Science Source Type: news

Allergists Available to All at Aerius(R) Allergy Clinic in Montreal and Laval Shopping Malls - Merck
MONTREAL, Aug. 14, 2012 (GLOBE NEWSWIRE) -- Following the great success of the Allergy Clinics in past years, Merck Consumer Care is pleased to host for a third consecutive year, the Allergy Clinic in local shopping malls.
Source: Medical News (via PRIMEZONE) - August 14, 2012 Category: Pharmaceuticals Source Type: news