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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 21.
Duodenal gastrointestinal stromal tumors: Review on clinical and surgical aspects
Conclusions: Duodenal GISTs have uncertain malignant potential, and they may be asymptomatic, or present with abdominal pain or bleeding. A preoperative diagnosis can be difficult to obtain. Endoscopic ultrasound and fine needle aspiration cytology (FNAC) may be helpful. Surgical R0 resection remains the only curative approach. However, owing to the complex anatomy of the duodenum, limited resection is not always feasible. In these cases, extensive procedures such as pancreaticoduodenectomy or pancreas-preserving duodenectomy are the treatment of choice.
Source: International Journal of Surgery - September 17, 2012 Category: Surgery Authors: G. Cavallaro, A. Polistena, G. D'Ermo, G. Pedullà, G. De Toma Tags: Reviews Source Type: research
The AL 333-160 fourth metatarsal from Hadar compared to that of humans, great apes, baboons and proboscis monkeys: Non-conclusive evidence for pedal arches or obligate bipedality in Hadar hominins.
This study highlights evolutionary misconceptions underlying the practice of using localized anatomy and/or a single bony element to reconstruct overall locomotor behaviors and of summarizing great ape structure and behavior based on non-statistically representative samples of only a few living great ape species. PMID: 22995931 [PubMed - as supplied by publisher]
Source: Homo - September 17, 2012 Category: Physiology Authors: Mitchell PJ, Sarmiento EE, Meldrum DJ Tags: Homo Source Type: research
Anomalous high bifurcation of the common femoral artery at the groin: management of GSV incompetence with endovenous laser ablation.
CONCLUSION: EVLA is a safe treatment for SFJ/GSV incompetence in the presence of vascular anomalies that have historically resulted in serious vascular complications from surgery. PMID: 22987231 [PubMed - as supplied by publisher]
Source: Phlebology - September 17, 2012 Category: Internal Medicine Authors: Lekich C, Campbell W, Walton S, Hannah P Tags: Phlebology Source Type: research
Sectarianism and the problem of overpopulation: political representations of reproduction in two low-income neighbourhoods of Beirut, Lebanon.
Abstract The role of confessionalism in the Lebanese healthcare sector, especially since the resolution of the Lebanese civil war (1975-1990), has yet to discussed at length in reproductive health research. Using biopolitical and structural violence models to describe how community leaders in two low-income neighbourhoods in Beirut describe reproductive healthcare - specifically through judgments of perceived sect size vis-à-vis perceived use of birth control measures - this paper attempts to provide critical analysis of the state of reproductive health in this setting. By using a theoretical model of analysis, wh...
Source: Culture, Health and Sexuality - September 17, 2012 Category: Global & Universal Authors: Premkumar A, Salem K, Akhtar S, Deeb ME, Messersmith LJ Tags: Cult Health Sex Source Type: research
Influence of L1-CAM expression of breast cancer cells on adhesion to endothelial cells
Conclusions Our experiments indicate that L1-CAM expression on breast cancer cells can promote adherence to activated endothelial cells by binding to endothelial L1-CAM or ALCAM. This mechanism might lead to increased metastasis and a poor prognosis in L1-CAM-positive carcinomas in vivo. Therefore, L1-CAM might be a suitable therapeutic target in breast cancers with a high L1-CAM expression. Content Type Journal ArticleCategory Original PaperPages 1-15DOI 10.1007/s00432-012-1306-zAuthors Virginia Dippel, Department of Gynecology, University Medical Center Hamburg-Eppendorf, Martinistr. 52, Bldg. N27...
Source: Journal of Cancer Research and Clinical Oncology - September 16, 2012 Category: Cancer & Oncology Tags: Journal of Cancer Research and Clinical Oncology Source Type: research
Stereology as a valuable tool in the toolbox of testicular research.
Abstract The morphology of the testis may be altered in various developmental, physiological and pathological conditions and these changes are reflected by the alterations in the reproductive capacity. Studying testicular morphology under these conditions or following therapeutic interventions relies on quantitative data. Design-based stereology provides quantitative morphological data on the most important characteristics of the testis. The total volume of the testis, seminiferous tubules, interstitial tissues and germinal epithelium, length, diameter and cross sectional area of the tubules as well as the number o...
Source: Annals of Anatomy - September 16, 2012 Category: Anatomy Authors: Noorafshan A Tags: Ann Anat Source Type: research
Types of imaging, part 2: an overview of fluorescence microscopy.
PMID: 22941879 [PubMed - in process]
Source: Anatomical Record - September 15, 2012 Category: Anatomy Authors: Jensen EC Tags: Anat Rec (Hoboken) Source Type: research
The Gross Anatomy of the Original and Regenerated Tail in the Green Anole (Anolis carolinensis).
This study investigates the gross anatomy of the original and the regenerated tail in the green anole (Anolis carolinensis). Dissections were conducted on 24 original and 13 regenerated tails. While the extrinsic muscles of the original tail in A. carolinensis are similar to those in other known Anolis lizard species, the extent of the origins of m. caudofemoralis longus and m. caudofemoralis brevis is more restricted. These differences may underlie variation in locomotor performance among anole ecomorphs. The intrinsic muscles of the original tail are also described, confirming previous findings and documenting new detail...
Source: Anatomical Record - September 15, 2012 Category: Anatomy Authors: Ritzman TB, Stroik LK, Julik E, Hutchins ED, Lasku E, Denardo DF, Wilson-Rawls J, Rawls JA, Kusumi K, Fisher RE Tags: Anat Rec (Hoboken) Source Type: research
Retrobulbar vasculature using 7-T magnetic resonance imaging with dedicated eye surface coil
Conclusions High-resolution 7-T MRI with a dedicated eye coil can provide unique high-resolution noninvasive images of retro-orbital and posterior ocular structural and vascular anatomy and is able to resolve structures as small as the central retina vein. Content Type Journal ArticleCategory Oculoplastics and OrbitPages 1-7DOI 10.1007/s00417-012-2154-xAuthors John B. Christoforidis, Department of Ophthalmology, College of Medicine, The Ohio State University, Columbus, OH, USAPeter A. Wassenaar, Department of Radiology, College of Medicine, The Ohio State University, Columbus, OH, USAGreg A. Christof...
Source: Graefe's Archive for Clinical and Experimental Ophthalmology - September 15, 2012 Category: Opthalmology Tags: Graefe's Archive for Clinical and Experimental Ophthalmology Source Type: research
De Garengeot’s hernia: a comprehensive review
Conclusion Preoperative diagnosis of de Garengeot’s hernia is difficult due to its atypical clinical presentation. Further surgical treatment depends on the surgeon’s sound clinical judgment. Content Type Journal ArticleCategory ReviewPages 1-6DOI 10.1007/s10029-012-0993-3Authors V. Kalles, 1st Propaedeutic Surgical Clinic, AHEPA Hospital, Medical School, Aristotle University of Thessaloniki, P.Perimeni 1-2, Nea Smyrni, 17121 Athens, GreeceA. Mekras, 1st Propaedeutic Surgical Clinic, AHEPA Hospital, Medical School, Aristotle University of Thessaloniki, P.Perimeni 1-2, Nea Smyrni, 17121 Athens, Gr...
Source: Hernia - September 15, 2012 Category: Sports Medicine Tags: Hernia Source Type: research
High trefoil factor 1 (TFF1) expression in human retinoblastoma cells correlates with low growth kinetics, increased cyclin-dependent kinase (CDK) inhibitor levels and a selective down-regulation of CDK6
Abstract Trefoil factor family (TFFs) peptides facilitate epithelial restitution, but also effect cell proliferation and apoptosis of normal and various cancer cell lines. In a recent study by our group, TFF2 expression was demonstrated in the murine retina, where it exhibits pro-proliferative and pro-apoptotic effects. In the present study, we investigated the expression and function of TFF peptides in eight human retinoblastoma cell lines. TFF1 was the only TFF peptide expressed at detectable levels in immunoblots of retinoblastoma cells. TFF1 expression levels were highly variable in different retinoblast...
Source: Histochemistry and Cell Biology - September 15, 2012 Category: Biomedical Science Tags: Histochemistry and Cell Biology Source Type: research
Giant basilar artery aneurysm and unexpected death
Content Type Journal ArticleCategory Lessons from the MuseumPages 1-3DOI 10.1007/s12024-012-9381-7Authors Roger W. Byard, Discipline of Anatomy and Pathology, School of Health Sciences, The University of Adelaide, Level 3 Medical School North Building, Frome Road, Adelaide, 5005 Australia Journal Forensic Science, Medicine, and PathologyOnline ISSN 1556-2891Print ISSN 1547-769X
Source: Forensic Science, Medicine, and Pathology - September 15, 2012 Category: Forensic Medicine Tags: Forensic Science, Medicine, and Pathology Source Type: research
Anatomical and CT angiographic study of superior gluteal neurovascular pedicle: implications for hip surgery
Conclusions This study analyzed the relationships between superior gluteal neurovascular pedicle and the GT in vivo (considering also the muscular tone), showing that during direct lateral access a safe area of 4.7 cm exists from the GT to the SGN and of 3.5 cm to its lower rami. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00276-012-1014-zAuthors Carla Stecco, Section of Anatomy, Department of Molecular Medicine, University of Padova, Padua, ItalyVeronica Macchi, Section of Anatomy, Department of Molecular Medicine, University of Padova, Padua, ItalyLuca Bagg...
Source: Surgical and Radiologic Anatomy - September 15, 2012 Category: Anatomy Tags: Surgical and Radiologic Anatomy Source Type: research
The lumbar sympathetic trunk: its visibility and distance to two anatomical landmarks
Conclusions The costal process is a usable landmark for fluoroscopic guidance and the psoas major for CT- and MRI-guided techniques. The LST is clearly visible in MR and CT images, which gives both techniques a decisive advantage over fluoroscopy concerning the block of the LST due to a visible target. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00276-012-1015-yAuthors Georg C. Feigl, Institute of Anatomy, Medical University of Graz, Harrachgasse 21, 8010 Graz, AustriaManuel Kastner, Institute of Anatomy, Medical University of Graz, Harrachgasse 21, 8010 Graz, AustriaH...
Source: Surgical and Radiologic Anatomy - September 15, 2012 Category: Anatomy Tags: Surgical and Radiologic Anatomy Source Type: research
The use of the Anaconda stent graft for abdominal aortic aneurysms.
Abstract The AnacondaTM is a modular bifurcated stent-graft of woven polyester and nitinol ring stents that has been commercially available since 2005. It was the first truly repositionable stent-graft and features a magnet wire contralateral limb cannulation system. It has excellent fixation and sealing properties and its ring stent construction results in it being highly conformable and therefore applicable in angulated and tortuous anatomy. PMID: 22955552 [PubMed - in process]
Source: The Journal of Cardiovascular Surgery - September 15, 2012 Category: Cardiovascular & Thoracic Surgery Authors: Bungay P Tags: J Cardiovasc Surg (Torino) Source Type: research
The use of Endurant stent-graft for abdominal aortic aneurysm: the story about extension of Instruction for Use with persistent good results of stent-graft latest generation.
Abstract The Endurant stent-graft (Medtronic, Inc., Minneapolis, MN, USA) is a latest generation device for the treatment of abdominal aortic aneurysm. The idea behind designing such a graft came from the intention to broad the instruction for use (IFU) and to enable it to treat more challenging anatomy including the 10mm neck lengths, and more severe suprarenal and infrarenal angulations. Endurant stent-graft has active fixation through suprarenal stent with anchoring pins to provide migration resistance, optimized heights of stents and spacing between them for improved flexibility and conformability, low-profile ...
Source: The Journal of Cardiovascular Surgery - September 15, 2012 Category: Cardiovascular & Thoracic Surgery Authors: Rancic Z, Pecoraro F, Pfammatter T, Banzic I, Klein H, Kyriakidis K, Mayer D, Lachat M Tags: J Cardiovasc Surg (Torino) Source Type: research
Evaluation and Management of Rectourethral Fistula Following Radiation Treatment for Prostate Cancer
Abstract Rectourethral Fistula (RUF) is an unusual entity with severe consequences to patients. Radiation induced RUF is an infrequent complication following prostate cancer treatment. Evaluation and management of radiation induced RUF is not uniform. A variety of alternatives are offered to manage RUF, including but not limited to the transanal, transrectal approach (York-Mason), pure perineal and combined abdomino-perineal approaches. It is of utmost importance that the genitourinary reconstructive surgeon be familiar with the etiology, anatomy and options to treat RUF. Treatment strategies must be tailore...
Source: Current Bladder Dysfunction Reports - September 15, 2012 Category: Urology & Nephrology Tags: Current Bladder Dysfunction Reports Source Type: research
What can imaging tell us about physiology? Lung growth and regional mechanical strain
The interplay of mechanical forces transduces diverse physico-biochemical processes to influence lung morphogenesis, growth, maturation, remodeling and repair. Because tissue stress is difficult to measure in vivo, mechano-sensitive responses are commonly inferred from global changes in lung volume, shape, or compliance and correlated with structural changes in tissue blocks sampled from postmortem-fixed lungs. Recent advances in noninvasive volumetric imaging technology, nonrigid image registration, and deformation analysis provide valuable tools for the quantitative analysis of in vivo regional anatomy and air and tissue...
Source: Journal of Applied Physiology - September 15, 2012 Category: Physiology Authors: Hsia, C. C. W., Tawhai, M. H. Tags: HIGHLIGHTED TOPIC Source Type: research
Canal Configuration in the Mesiobuccal Root of the Maxillary First Molar and Its Endodontic Significance
The ultimate objective of endodontic therapy has been stated to be the obliteration of the prepared root canal space with an inert material in order to restore the integrity and state of good health of the treated tooth in the dental arch . According to Ingle , the most common cause of endodontic failure is apical percolation, with the largest percentage of cases failing due to incomplete canal obliteration. Other reasons for failure in this category include leaving a canal completely unfilled and inadvertently removing a silver point. Quite often a canal is left unfilled because the operator has failed to recognize its pr...
Source: Journal of Endodontics - September 14, 2012 Category: Dentistry Authors: Franklin S. Weine, Harry J. Healey, Harold Gerstein, Leonard Evanson Tags: In Remembrance Source Type: research
Microdomains in Forebrain Spines: an Ultrastructural Perspective
Abstract Glutamatergic axons in the mammalian forebrain terminate predominantly onto dendritic spines. Long-term changes in the efficacy of these excitatory synapses are tightly coupled to changes in spine morphology. The reorganization of the actin cytoskeleton underlying this spine “morphing” involves numerous proteins that provide the machinery needed for adaptive cytoskeletal remodeling. Here, we review recent literature addressing the chemical architecture of the spine, focusing mainly on actin-binding proteins (ABPs). Accumulating evidence suggests that ABPs are organized into functionally distinct...
Source: Molecular Neurobiology - September 14, 2012 Category: Neurology Tags: Molecular Neurobiology Source Type: research
Robotic-assisted pedicle screw placement: lessons learned from the first 102 patients
Conclusion Of the 960 screws that were implanted using the robot, 949 (98.9 %) were successfully and accurately implanted and 11 (1.1 %) were malpositioned, despite the fact that the majority of patients had significant spinal deformities and/or previous spine surgeries. “Tool skiving” was thought to be the inciting issue with the misplaced screws. Intraoperative anteroposterior and oblique fluoroscopic imaging for registration is critical and was the limiting issue in four of the seven aborted cases. Content Type Journal ArticleCategory Original ArticlePages 1-6DOI 10.1007/s00586-012-2...
Source: European Spine Journal - September 14, 2012 Category: Orthopaedics Tags: European Spine Journal Source Type: research
Chyloretroperitoneum following anterior spinal surgery.
Abstract Injury to the lymphatic channels is a rare and relatively unknown complication of anterior approaches to the lumbar spine and can cause fluid to build up in the retroperitoneal space, resulting in a lymphocele. If they enlarge sufficiently, these collections of chyle in the abdomen can cause pain and bowel ischemia, and can compress nearby organs. The authors report 4 cases in which anterior approaches to the lumbar spine were complicated by a postoperative retroperitoneal chylous fluid collection. They describe the anatomy of the lymphatic system and pathophysiology of this disease entity, review the spar...
Source: Journal of Neurosurgery.Spine - September 14, 2012 Category: Neurosurgery Authors: Hussain NS, Hanscom D, Oskouian RJ Tags: J Neurosurg Spine Source Type: research
Diurnal Rhythms of Spherical Refractive Error, Optical Axial Length, and Power in the Chick [Anatomy and Pathology]
Conclusions. We confirmed a diurnal variation in OAL and found diurnal variations in pupil size and MOR. Although changes in OAL explain the MOR previously observed in response to lenses and diffusers, they do not completely account for the observed diurnal variation of MOR nor for the reduction in hyperopia during normal development. We infer that the diurnal variation in MOR and normal emmetropization both result from small differences in the relative changes of OAL and ocular power.
Source: Investigative Ophthalmology - September 14, 2012 Category: Opthalmology Authors: Campbell, M. C. W., Bunghardt, K., Kisilak, M. L., Irving, E. L. Tags: Anatomy and Pathology Source Type: research
Retinal Thickening in HLA-B27-Associated Acute Anterior Uveitis: Evolution with Time and Association with Severity of Inflammatory Activity [Retina]
Conclusions. Retinal thickness in eyes affected with AAU presents a steep increase over 3 to 4 weeks and then gradually decreases. Severity of inflammation at baseline predicts the amount of retinal thickening in affected eyes. A characteristic pattern of temporal response of retinal anatomy to inflammatory stimuli seems to arise.
Source: Investigative Ophthalmology - September 14, 2012 Category: Opthalmology Authors: Balaskas, K., Ballabeni, P., Guex-Crosier, Y. Tags: Retina Source Type: research
Is the transverse acetabular ligament a reliable cup orientation guide?
Abstract Background and purpose It is controversial whether the transverse acetabular ligament (TAL) is a reliable guide for determining the cup orientation during total hip arthroplasty (THA). We investigated the variations in TAL anatomy and the TAL-guided cup orientation. Methods 80 hips with osteoarthritis secondary to hip dysplasia (OA) and 80 hips with osteonecrosis of the femoral head (ON) were examined. We compared the anatomical anteversion of TAL and the TAL-guided cup orientation in relation to both disease and gender using 3D reconstruction of computed tomography (CT) images. Results Mean TAL antevers...
Source: Acta Orthopaedica - September 14, 2012 Category: Orthopaedics Authors: Abe H, Sakai T, Hamasaki T, Takao M, Nishii T, Nakamura N, Sugano N Tags: Acta Orthop Source Type: research
Muscle Patterning in Mouse and Human Abdominal Wall Development and Omphalocele Specimens of Humans.
Abstract Human omphalocele is a congenital defect of the abdominal wall in which the secondary abdominal wall structures (muscle and connective tissue) in an area centered around the umbilicus are replaced by a translucent membranous layer of tissue. Histological examination of omphalocele development and moreover the staging of normal human abdominal wall development has never been described. We hypothesized that omphalocele is the result of an arrest in the secondary abdominal wall development and predicted that we would observe delays in myoblast maturation and an arrest in secondary abdominal wall development. ...
Source: Anatomical Record - September 14, 2012 Category: Anatomy Authors: Nichol PF, Corliss RF, Yamada S, Shiota K, Saijoh Y Tags: Anat Rec (Hoboken) Source Type: research
Wnt/β-Catenin Signaling Pathway Upregulates c-Myc Expression to Promote Cell Proliferation of P19 Teratocarcinoma Cells.
In conclusion, activation of the Wnt/β-catenin pathway could promote the proliferation and inhibit the differentiation of mouse teratocarcinoma cells by upregulation of c-myc expression. Anat Rec, 2012. © 2012 Wiley Periodicals, Inc. PMID: 22976998 [PubMed - as supplied by publisher]
Source: Anatomical Record - September 14, 2012 Category: Anatomy Authors: Zhang S, Li Y, Wu Y, Shi K, Bing L, Hao J Tags: Anat Rec (Hoboken) Source Type: research
Comparing the Distribution of Strains with the Distribution of Bone Tissue in a Human Mandible: A Finite Element Study.
Abstract Comparative anatomy and experimental studies suggest that the mass and distribution of tissue within a bone is adapted to the strains the bone experiences during function. Finite element analysis is a powerful tool that can be used to investigate this since it allows the creation of hypothetical models with unadapted morphology. Here we use FE models of a human mandible with modified internal morphology to study the relationships between the gross distribution of bone tissue (i.e., the presence or absence of bone in a certain area), the variation of cortical bone thickness within the mandible and the distr...
Source: Anatomical Record - September 14, 2012 Category: Anatomy Authors: Gröning F, Fagan M, O'higgins P Tags: Anat Rec (Hoboken) Source Type: research
A new ontology (structured hierarchy) of human developmental anatomy for the first 7 weeks (Carnegie stages 1-20).
Abstract This paper describes a new ontology of human developmental anatomy covering the first 49 days [Carnegie stages (CS)1-20], primarily structured around the parts of organ systems and their development. The ontology includes more than 2000 anatomical entities (AEs) that range from the whole embryo, through organ systems and organ parts down to simple or leaf tissues (groups of cells with the same morphological phenotype), as well as features such as cavities. Each AE has assigned to it a set of facts of the form <AE><relationship><parent>, with the relationships including starts_at and end...
Source: Journal of Anatomy - September 14, 2012 Category: Anatomy Authors: Bard J Tags: J Anat Source Type: research
Prospective Evaluation of Defibrillation Threshold and Postshock Rhythm in Young ICD Recipients
Conclusions: These data suggest that many pediatric ICD patients have low DFTs and adequate postshock escape rhythm. This may help determine appropriate parameters for future design of pediatric‐specific ICDs. (PACE 2012;00:1–7)
Source: Pacing and Clinical Electrophysiology : PACE - September 14, 2012 Category: Cardiology Authors: ANDREW E. RADBILL, JOHN K. TRIEDMAN, CHARLES I. BERUL, EDWARD P. WALSH, MARK E. ALEXANDER, GREGORY WEBSTER, FRANK CECCHIN Source Type: research
Comparing the Distribution of Strains with the Distribution of Bone Tissue in a Human Mandible: A Finite Element Study
Abstract Comparative anatomy and experimental studies suggest that the mass and distribution of tissue within a bone is adapted to the strains the bone experiences during function. Finite element analysis is a powerful tool that can be used to investigate this since it allows the creation of hypothetical models with unadapted morphology. Here we use FE models of a human mandible with modified internal morphology to study the relationships between the gross distribution of bone tissue (i.e., the presence or absence of bone in a certain area), the variation of cortical bone thickness within the mandible and the distribution ...
Source: The Anatomical Record Part A: Discoveries in Molecular, Cellular, and Evolutionary Biology - September 14, 2012 Category: Molecular Biology Authors: Flora Gröning, Michael Fagan, Paul O'higgins Tags: Full Length Article Source Type: research
Bicuspid aortic valve and thoracic aortic aneurysm: three patient populations, two disease phenotypes, and one shared genotype.
Abstract Bicuspid aortic valve (BAV) and thoracic aortic aneurysm (TAA) are two discrete cardiovascular phenotypes characterized by latent progressive disease states. There is a clear association between BAV and TAA; however the nature and extent of this relationship is unclear. There are both distinct and overlapping developmental pathways that have been established to contribute to the formation of the aortic valve and the aortic root, and the mature anatomy of these different tissue types is intimately intertwined. Likewise, human genetics studies have established apparently separate and common contributions to ...
Source: Cardiology Research and Practice - September 13, 2012 Category: Cardiology Authors: Hinton RB Tags: Cardiol Res Pract Source Type: research
Effects of experimentally induced hyperthyroidism on central hypothalamic–pituitary–adrenal axis function in rats: in vitro and in situ studies
Abstract Hyperthyroidism is associated with hypercorticosteronemia, although the locus that is principally responsible for the hypercorticosteronism remains unclear. The purpose of this study was to assess the effects of hyperthyroidism on the functional integrity of the hypothalamic–pituitary–adrenal (HPA) axis, to identify the locus in the HPA axis that is principally affected, and address the time-dependent effects of alterations in thyroid status. The functional integrity of each component of the HPA axis was examined in vitro and in situ in sham-thyroidectomized male Sprague–Dawley rats given plac...
Source: Pituitary - September 13, 2012 Category: Endocrinology Tags: Pituitary Source Type: research
Utility of the Short Double-Balloon Enteroscope to Perform Pancreaticobiliary Interventions in Patients with Surgically Altered Anatomy in a US Multicenter Study
Conclusions The current study demonstrates that DBE assisted ERCP for pancreaticobiliary interventions using a short enteroscope are feasible in patients with surgically altered anatomy. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s10620-012-2385-zAuthors Ali A. Siddiqui, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Thomas Jefferson University Hospital, Philadelphia, PA, USAAdib Chaaya, Division of Gastroenterology, Fox Chase Cancer Center, Philadelphia, PA, USACorbett Shelton, Division of Gastroenterology and Hepatology, Department of In...
Source: Digestive Diseases and Sciences - September 13, 2012 Category: Gastroenterology Tags: Digestive Diseases and Sciences Source Type: research
Electrophysiological changes precede morphological changes to frontal cortical pyramidal neurons in the rTg4510 mouse model of progressive tauopathy
Abstract Whole-cell patch-clamp recordings and high-resolution morphometry were used to assess functional and structural properties of layer 3 pyramidal neurons in early (<4 months) and advanced (>8 months) stages of tauopathy in frontal cortical slices prepared from rTg4510 tau mutant (P301L) mice. In early tauopathy, dendritic architecture is preserved. In advanced tauopathy, neurons can be categorized as either “atrophic” (58 %)—exhibiting marked atrophy of the apical tuft, or “intact” (42 %)—with normal apical tufts and, in some instances, proliferative sprouting of ...
Source: Acta Neuropathologica - September 13, 2012 Category: Neurology Tags: Acta Neuropathologica Source Type: research
Analysis of emotionality and locomotion in radio-frequency electromagnetic radiation exposed rats
Abstract In the current study the modulatory role of mobile phone radio-frequency electromagnetic radiation (RF-EMR) on emotionality and locomotion was evaluated in adolescent rats. Male albino Wistar rats (6–8 weeks old) were randomly assigned into the following groups having 12 animals in each group. Group I (Control): they remained in the home cage throughout the experimental period. Group II (Sham exposed): they were exposed to mobile phone in switch-off mode for 28 days, and Group III (RF-EMR exposed): they were exposed to RF-EMR (900 MHz) from an active GSM (Global system for mobile communi...
Source: Neurological Sciences - September 13, 2012 Category: Neurology Tags: Neurological Sciences Source Type: research
Postmortem imaging exposed: an aid in MR imaging of musculoskeletal structures
Conclusion Various factors were identified that affect postmortem MR image quality of MSK structures. Postmortem MR image quality was good, except for images of the fixated specimen. Freezing is the preferred method of conservation for specimens that are to be subjected to postmortem MRI. Content Type Journal ArticleCategory Review ArticlePages 1-6DOI 10.1007/s00256-012-1515-1Authors A. D. van der Made, Department of Radiology, Academic Medical Center, Amsterdam, The NetherlandsM. Maas, Department of Radiology, Academic Medical Center, Amsterdam, The NetherlandsL. F. M. Beenen, Department of Radiolo...
Source: Skeletal Radiology - September 13, 2012 Category: Radiology Tags: Skeletal Radiology Source Type: research
A measure to evaluate deformable registration fields in clinical settings.
Abstract Deformable registration has migrated from a research topic to a widely used clinical tool that can improve radiotherapeutic treatment accuracy by tracking anatomical changes. Although various mathematical formulations have been reported in the literature and implemented in commercial software, we lack a straightforward method to verify a given solution in routine clinical use. We propose a metric using concepts derived from vector analysis that complements the standard evaluation tools to identify unrealistic wrappings in a displacement field. At the heart of the proposed procedure is identification of vor...
Source: Journal of Applied Clinical Medical Physics - September 13, 2012 Category: Physics Authors: Schreibmann E, Pantalone P, Waller A, Fox T Tags: J Appl Clin Med Phys Source Type: research
Short-Term Outcomes of the C3 Excluder for Patients With Abdominal Aortic Aneurysms and Unfavorable Proximal Aortic Seal Zones
Conclusions: The C3 Excluder endoprosthesis significantly reduces the need for proximal extension cuffs in patients with unfavorable aortic neck anatomy compared with the traditional Excluder with identical short-term clinical outcomes. Repositionable grafts could increase the number of patients who can effectively be treated with EVAR.
Source: Annals of Vascular Surgery - September 13, 2012 Category: Surgery Authors: Matthew R. Smeds, Donald L. Jacobs, Gary J. Peterson, Brian G. Peterson Tags: Papers Presented to the Peripheral Vascular Surgery Society - 22nd Annual Winter Meeting Source Type: research
Magnetic resonance imaging of muscle disease: A pattern‐based approach
We present a classification scheme that categorizes abnormal MR appearances of muscle into 4 main pattern descriptors: (1) distribution; (2) change in size and shape; (3) T1 signal; and (4) T2 signal. Each category is further subdivided into the various patterns seen on MRI. Such an approach allows one to systematically assess abnormal findings on muscle MRI studies and ascertain clues to the diagnosis or differential diagnosis, particularly when findings are correlated with the clinical context. Muscle Nerve 46: 520–481, 2012
Source: Muscle and Nerve - September 13, 2012 Category: Internal Medicine Authors: Andreu F. Costa, Gina A. Di Primio, Mark E. Schweitzer Tags: Invited Review Source Type: research
Contributions of Developmental Studies in the Dogfish Scyliorhinus canicula to the Brain Anatomy of Elasmobranchs: Insights on the Basal Ganglia
Brain Behav Evol 2012;80:127–141 (DOI:10.1159/000339871)
Source: Brain, Behavior and Evolution - September 12, 2012 Category: Neurology Source Type: research
3-T MRI of the biliary tract variations
Conclusion MRCP studies conducted using 3-T MRI devices may reveal similar or greater numbers of variations when compared to the existing MRCP studies in the literature. 3-T MRI shows a couple of variations. Pointing out these anatomical variations before the surgical intervention may prevent possible iatrogenic traumas. Donors with unsuitable variations for liver transplant may be spotted out at an early phase through the MRCP and certain operations with a high morbidity rate may thus be avoided. Content Type Journal ArticleCategory Anatomic Bases of Medical, Radiological and Surgical TechniquesPage...
Source: Surgical and Radiologic Anatomy - September 12, 2012 Category: Anatomy Tags: Surgical and Radiologic Anatomy Source Type: research
Complex anomalies of type 1 proatlantal intersegmental artery and aortic arch variations
Conclusion To our knowledge, this is the first report of a type 1 PIA associated with multiple vascular anomalies of the aortic arch, such as ARSA and origin of the left VA from the arch. In cases of persistent anastomoses between the carotid and vertebrobasilar arteries, such as PIAs, imaging examination should include the aortic arch to identify associated vascular variations. Content Type Journal ArticleCategory Anatomic VariationsPages 1-4DOI 10.1007/s00276-012-1017-9Authors Naoko Saito, Department of Radiology, Saitama Medical University International Medical Center, 1397-1 Yamane, Hidaka, Sait...
Source: Surgical and Radiologic Anatomy - September 12, 2012 Category: Anatomy Tags: Surgical and Radiologic Anatomy Source Type: research
The effects of AMPA receptor blockade in the prelimbic cortex on systemic and ventral tegmental area opiate reward sensitivity
Conclusions These findings suggest a critical role for intra-PLC AMPA receptor transmission in the processing of opiate reward signaling. Furthermore, blockade of AMPA transmission specifically within the PLC is capable of switching opiate reward processing to a DA-dependent reward system, independently of previous opiate exposure history. Content Type Journal ArticleCategory Original InvestigationPages 1-9DOI 10.1007/s00213-012-2852-4Authors Xavier De Jaeger, Department of Anatomy and Cell Biology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada N6C...
Source: Psychopharmacology - September 12, 2012 Category: Psychiatry Tags: Psychopharmacology Source Type: research
We found the comments of Dr. Gaibazzi very thoughtful. We certainly agree that echocardiography should be the “first line” technique for evaluation of left ventricular function because it is widely available, easily done, very cost efficient, and does not require ionizing radiation. Furthermore, contrast media are a possible way to improve the diagnostic performance of echocardiography (). However, there is also evidence that computed tomography (CT) shows better reproducibility and accuracy than contrast-enhanced (CE) echocardiography () and may be favored in certain patients (e.g., those with deformed ventricular anatomy).
Source: Journal of the American College of Cardiology - September 12, 2012 Category: Cardiology Authors: Johannes Greupner, Adrian C. Borges, Marc Dewey Tags: Letters to the Editor Source Type: research
Cardiac Magnetic Resonance and the Need for Routine Cardiac Catheterization in Single Ventricle Patients Prior to Fontan: A Comparison of 3 Groups: Pre-Fontan CMR Versus Cath Evaluation
Conclusions: Single ventricle patients not requiring an intervention can undergo successful Fontan completion with CMR and echo alone with similar short-term outcomes to C, which was used as a control, preventing an invasive test and exposure to radiation. CMR can add information in a significant number of patients. Cath and CMR are utilized together for interventions and assessment of aortopulmonary collaterals.
Source: Journal of the American College of Cardiology - September 12, 2012 Category: Cardiology Authors: Mark A. Fogel, Thomas W. Pawlowski, Kevin K. Whitehead, Matthew A. Harris, Marc S. Keller, Andrew C. Glatz, Winnie Zhu, David Shore, Laura K. Diaz, Jonathan J. Rome Tags: Congenital Heart Disease Source Type: research
Novel triplet of flexor muscles in the posterior tentacles of the snail, Helix pomatia.
Abstract The anatomy of three novel flexor muscles in the posterior tentacles of Helix pomatia is described. The muscles originate from the ventral side of the sensory pad and are anchored at different sites in the base of the tentacle stem. The muscles span the tentacle and always take the length of the stem which depends on the rate of tentacle protrusion indicating that the muscles are both contractile and extremely stretchable. The three anchoring points at the base of the stem determine three space axes along which the contraction of a muscle or the synchronous contraction of the muscles can move the tentacle ...
Source: Acta Biologica Hungarica - September 12, 2012 Category: Biology Authors: Hernádi L, Teyke T Tags: Acta Biol Hung Source Type: research
A Voluntary Breath-Hold Treatment Technique for the Left Breast With Unfavorable Cardiac Anatomy Using Surface Imaging
Conclusions: Daily real-time surface imaging ensures accurate and reproducible positioning for BH treatment of left-sided breast cancer patients with unfavorable cardiac anatomy.
Source: International Journal of Radiation Oncology * Biology * Physics - September 12, 2012 Category: Radiology Authors: David P. Gierga, Julie C. Turcotte, Gregory C. Sharp, Daniel E. Sedlacek, Christopher R. Cotter, Alphonse G. Taghian Tags: Physics Contributions Source Type: research
Acute injury affects lubricin expression in knee menisci: An immunohistochemical study.
Abstract The aim of this study was to investigate for the first time lubricin expression in intact menisci and in menisci from patients with recent knee joint injury using histology, immunohistochemistry, Western blotting and gene expression analysis, to provide insights into pathological processes affecting meniscal tissue. Lubricin expression was studied in vivo in 20 patients (14 males and 6 females) with recent joint injury subjected to arthroscopic partial meniscectomy and in vitro in fibroblast-like cells from meniscus tissue to establish whether it is down-regulated following acute traumatic knee injury. The...
Source: Annals of Anatomy - September 12, 2012 Category: Anatomy Authors: Musumeci G, Loreto C, Carnazza ML, Cardile V, Leonardi R Tags: Ann Anat Source Type: research
Flow control technique to prevent distal embolization during mechanical thrombectomy
We present a case using an endovascular flow control technique that can be used for reducing distal embolic events during endovascular recanalization of aortoiliac occlusive disease. This technique has been used in four patients so far (two with native anatomy and two with aorto-bi-iliac grafts) with no evidence of angiographic or clinical embolic complications.
Source: Journal of Vascular Surgery - September 12, 2012 Category: Surgery Authors: Mathew Wooster, Daniel Kloda, Jacob Robison, Joseph Hart, Marcelo Guimaraes, Thomas Todoran, Claudio Schönholz Tags: Vascular and endovascular techniques Source Type: research