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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 32.

Microvascular reconstruction of the mouth, face and jaws. Oromandibular reconstruction – free fibula flap
We present our experience with the free fibula flap used for oromandibular reconstruction; this was undertaken in 21 patients following resective surgery for malignant pathology, cytologically benign but biologically aggressive odontogenic pathology and radiation induced osteonecrosis. We also review the history, surgical anatomy, surgical assessment and potential complications that are relevant to the free fibula flap.
Source: Australian Dental Journal - July 23, 2012 Category: Dentistry Authors: GR Hoffman, S Islam, RL Eisenberg Tags: CLINICAL REPORT Source Type: research

Comparison of Everolimus-Eluting and Sirolimus-Eluting Coronary Stents: 1-Year Outcomes from the Randomized Evaluation of Sirolimus-Eluting Versus Everolimus-Eluting Stent Trial (RESET).
CONCLUSIONS: One-year clinical and angiographic outcome after EES implantation was non-inferior to and not different from that after SES implantation in a stable coronary artery disease population with relatively less complex coronary anatomy. One-year clinical outcome after both EES- and SES-use was excellent with low rate of TLR and very low rate of stent thrombosis. CLINICAL TRIAL REGISTRATION INFORMATION: clinicaltrials.gov; Identifier: NCT01035450. PMID: 22824435 [PubMed - as supplied by publisher]
Source: Circulation - July 23, 2012 Category: Cardiology Authors: Kimura T, Morimoto T, Natsuaki M, Shiomi H, Igarashi K, Kadota K, Tanabe K, Morino Y, Akasaka T, Takatsu Y, Nishikawa H, Yamamoto Y, Nakagawa Y, Hayashi Y, Iwabuchi M, Umeda H, Kawai K, Okada H, Kimura K, Simonton CA, Kozuma K Tags: Circulation Source Type: research

Tunicamycin Inhibits PDGF-BB-Induced Proliferation and Migration of Vascular Smooth Muscle Cells Through Induction of HO-1.
In this study, we found that pretreatment with tunicamycin (Tm), an ER stress inducer, significantly inhibited platelet-derived growth factor (PDGF)-BB-induced VSMC proliferation and migration in a dose-dependent manner without causing significant apoptosis. Tm stimulated the expression of the antioxidant gene heme oxygenase-1 (HO-1) both at the transcriptional and translational levels, while reducing phosphorylation and activation of mitogen-activated protein (MAP) kinases. The negative regulative effects of Tm were associated with a decrease in cyclins and cyclin-dependent kinases (CDKs) activation. More importantly, HO-...
Source: Anatomical Record - July 23, 2012 Category: Anatomy Authors: Yi N, Chen SY, Ma A, Chen PS, Yao B, Liang TM, Liu C Tags: Anat Rec (Hoboken) Source Type: research

Reversed intestinal malrotation with concurrent cecal carcinoma
AbstractA 57‐year‐old man was admitted with a type 2 (ulcerated with clear margin) cancer in the cecum. Contrast‐enhanced CT showed that the superior mesenteric vein was anterior to the superior mesenteric artery, and the patient was suspected of having intestinal malrotation. A laparoscopic‐assisted ileocecal resection was performed. At operation, the cecum and the transverse colon passed through the root of the mesentery behind the superior mesenteric artery with the duodenum. Therefore, this was thought to be a reversed‐type intestinal malrotation. After the operation, 3D‐CT colonography with duodenography i...
Source: Asian Journal of Endoscopic Surgery - July 23, 2012 Category: Surgery Authors: M Morimoto, H Horie, H Kumano, A Lefor, K Utano, Y Yasuda Tags: Case Report Source Type: research

Fracture Mimics on Temporal Bone CT: A Guide for the Radiologist
CONCLUSION. Small normal anatomic fissures are now routinely visualized with the increasing use of MDCT in trauma patients. An awareness of these structures is required by radiologists interpreting studies with fine temporal bone slices to prevent erroneous interpretation.
Source: American Journal of Roentgenology - July 23, 2012 Category: Radiology Authors: Kwong, Y., Yu, D., Shah, J. Tags: Neuroradiology/Head and Neck Imaging Source Type: research

Performing Fluoroscopically Guided Interlaminar Lumbar Epidural Injections
CONCLUSION. Low back pain and radiculopathy afflict millions of people each year with enormous socioeconomic ramifications and individual disability. This condition has a prevalence of at least 13% and is the second most common symptom-related cause for office visits in the United States. Epidural injections have become the most commonly performed intervention in the management of chronic low back pain in the United States.
Source: American Journal of Roentgenology - July 23, 2012 Category: Radiology Authors: Rosas, H. G., Lee, K. S. Tags: Musculoskeletal Imaging Source Type: research

Postnatal alteration of collapsin response mediator protein 4 mRNA expression in the mouse brain.
Abstract Collapsin response mediator protein 4 (CRMP4) is a molecular marker for immature neurons but only limited information is available on the spatiotemporal gene expression changes of Crmp4 in the developing rodent. In the present study, the variation of CRMP4 mRNA expression in the mouse brain was investigated from postnatal day (PD) 0 (the day of birth) to adulthood by in situ hybridization. The hybridization signals were broadly detected on PD0 and regional changes in expression during development were noted. Expression patterns of CRMP4 mRNA were classified into the following three types: (i) signals that ...
Source: Journal of Anatomy - July 22, 2012 Category: Anatomy Authors: Tsutiya A, Ohtani-Kaneko R Tags: J Anat Source Type: research

The oblique branch trap in the harvest of the anterolateral thigh myocutaneous flap
AbstractA 67‐year‐old man with squamous cell carcinoma underwent reconstruction with a free anterolateral thigh myocutaneous flap. Unroofing the skin perforators found that the skin perforators originated from the oblique branch of the lateral circumflex femoral artery with no connections with the descending branch. Thus, the flap was harvested based on the oblique branch, leaving the descending branch in situ. Reconstruction was completed uneventfully and he had an excellent outcome at 1‐year follow‐up. The anterolateral thigh myocutaneous flap was reputed to be a technically easy flap to harvest. The perforators ...
Source: Microsurgery - July 22, 2012 Category: Surgery Authors: Chin‐Ho Wong Tags: Case Report Source Type: research

The use of thoracoscopy to enhance medical students' interest and understanding of thoracic anatomy
Conclusion: Incorporating live surgery using thoracoscopic video presentation in the gross anatomy teaching curriculum had high acceptance and satisfaction scores from first year medical students. The video increased students' interest in learning, in clinically applying anatomic fact, and in surgery as a future career.
Source: Annals of Thoracic Medicine - July 21, 2012 Category: Respiratory Medicine Authors: Sami A AlNassarWaseem HajjarSalah RahalJoanne CliftonRichard FinleyRavi Sidhu Source Type: research

Soft tissue coverage in open fractures of tibia
Conclusion: open fracture of the tibia which needs flap coverage should be treated with high priority of radical early debridement, rigid fixation, and early flap coverage. A majority of these wounds can be satisfactorily covered with local or regional nonmicrovascular flaps.
Source: Table of Contents : Indian Journal of Orthopaedics : 2007 - 41(1) - July 21, 2012 Category: Orthopaedics Authors: Jagannath B KamathM Shantaram ShettyThangam Verghese JoshuaAjith KumarHarshvardhanDeepak M Naik Source Type: research

Microsurgical anatomy of the infratentorial arteries: stereoscopic printing study
CONCLUSION: The microsurgical anatomy of the infratentorial arteries is complex and the stereoscopic images presented are an important tool for documentation.
Source: Jornal Vascular Brasileiro - July 20, 2012 Category: Surgery Source Type: research

Treating stress urinary incontinence in female patients with neuropathic bladder: the value of the autologous fascia rectus sling
Conclusion  The free autologous rectus fascia sling is a highly effective technique for the treatment of female stress incontinence in patients with neuropathic bladder, while the morbidity is mild. Content Type Journal ArticleCategory Urology - Original PaperPages 1-5DOI 10.1007/s11255-012-0247-4Authors Anastasios Athanasopoulos, Department of Urology, Medical School, University of Michigan, Ann Arbor, MI, USAKonstantinos Gyftopoulos, Department of Anatomy, Medical School, University of Patras, Patras, GreeceEdward J. McGuire, Department of Urology, Medical School, University of Michigan, Ann Arbor, ...
Source: International Urology and Nephrology - July 20, 2012 Category: Urology & Nephrology Tags: International Urology and Nephrology Source Type: research

Genomic analysis of the appearance of testicular oocytes in MRL/MpJ mice
In this study we focused on the autosomal genes and examined their relationship with this phenotype by analyzing the progeny from crosses between MRL mice and other strains. We first observed the male F1 progeny from the crosses between female A/J, C57BL/6 (B6), BALB/c, C3H/He, or DBA/2 mice and male MRL mice, and two consomic strains, male B6-YMRL and MRL-YB6. Testicular oocytes that were morphologically similar to those of MRL mice were detected in all mouse strains except BALBMRLF1; however, the incidence of testicular oocytes was significantly lower than that in MRL mice. The appearance of testicular oocytes in MR...
Source: Mammalian Genome - July 20, 2012 Category: Genetics & Stem Cells Tags: Mammalian Genome Source Type: research

The safety and feasibility of a less invasive distal femur closing wedge osteotomy technique: a cadaveric dissection study of the medial aspect of the distal femur
Conclusions  In this cadaveric dissection study, a less invasive approach to the medial side of the distal femur proved to be feasible and safe. Damage to the VM and its neurovascular structures is minimized as compared to the traditional subvastus approach. Content Type Journal ArticleCategory KneePages 1-8DOI 10.1007/s00167-012-2133-0Authors J. Visser, Department of Orthopaedics, University Medical Center Utrecht, Utrecht, The NetherlandsJ. -M. Brinkman, Department of Orthopaedics Maartenskliniek Woerden, Limb Deformity Reconstruction Unit, Polanerbaan 2, 3447 GN Woerden, The NetherlandsR. L. A. W. ...
Source: Knee Surgery, Sports Traumatology, Arthroscopy - July 20, 2012 Category: Orthopaedics Tags: Knee Surgery, Sports Traumatology, Arthroscopy Source Type: research

Characterization of the mucocutaneous junction of the human eyelid margin and meibomian glands with different biomarkers.
CONCLUSIONS: The present immunohistochemical findings lead to a better characterization of the MCJ. Additionally, the knowledge of distribution of biomarkers like cytokeratins, mucins and stem cells can be useful in the investigation of MCJ disturbances which occur in several disorders of the meibomian glands and the lid epithelium in the course of dry eye syndrome and especially meibomian gland dysfunction. PMID: 22877886 [PubMed - as supplied by publisher]
Source: Annals of Anatomy - July 20, 2012 Category: Anatomy Authors: Tektaş OY, Yadav A, Garreis F, Schlötzer-Schrehardt U, Schicht M, Hampel U, Bräuer L, Paulsen F Tags: Ann Anat Source Type: research

Two-handed endoscopic-directed vestibular nerve sectioning: case series and review of the literature.
Conclusions The endoscopic-directed approach represents a safe and effective method for performing vestibular nerve sectioning. Until now, the endoscope has been used primarily as an adjunct to the operating microscope in surgery at the cerebellopontine angle. In addition, previous endoscopic techniques typically require a third hand to manipulate the endoscope. With the 2-handed endoscopic-directed technique, however, the endoscope is used as the primary means of visualization, and the unique design of this endoscope allows for a bimanual procedure without the requirement of a cosurgeon. Advantages of using this techniqu...
Source: Journal of Neurosurgery - July 20, 2012 Category: Neurosurgery Authors: Cutler AR, Kaloostian SW, Ishiyama A, Frazee JG Tags: J Neurosurg Source Type: research

Exposing Exposure: Automated Anatomy-specific CT Radiation Exposure Extraction for Quality Assurance and Radiation Monitoring [Computer Applications]
Conclusion: Large-scale anatomy-specific radiation exposure data repositories can be created with high fidelity from existing digital image archives by using open-source informatics tools. ©RSNA, 2012 Supplemental material: http://radiology.rsna.org/lookup/suppl/doi:10.1148/radiol.12111822/-/DC1
Source: Radiology - July 20, 2012 Category: Radiology Authors: Sodickson, A., Warden, G. I., Farkas, C. E., Ikuta, I., Prevedello, L. M., Andriole, K. P., Khorasani, R. Tags: Informatics Computer Applications Source Type: research

Hip Capsule Dimensions in Patients With Femoroacetabular Impingement: A Pilot Study.
CONCLUSIONS: Knowledge of the capsular anatomy in patients with FAI before surgery is important to judge the postoperative changes and to plan potential further therapy including arthroscopic treatment of intraarticular adhesions. PMID: 22810156 [PubMed - as supplied by publisher]
Source: Clinical Orthopaedics and Related Research - July 19, 2012 Category: Orthopaedics Authors: Weidner J, Büchler L, Beck M Tags: Clin Orthop Relat Res Source Type: research

Transthoracic Echocardiography Simulation Is an Efficient Method to Train Anesthesiologists in Basic Transthoracic Echocardiography Skills.
Discussion:This prospective randomized study demonstrated that anesthesiology residents trained with simulation acquired better skills in TTE image acquisition and anatomy identification on volunteer subjects. The educational benefit of simulation persisted even with introduction of hands-on instruction with volunteer subjects in both groups. The impact of these short-term educational approaches on longer-term retention and actual clinical application warrants further investigation. PMID: 22822190 [PubMed - as supplied by publisher]
Source: Anesthesia and Analgesia - July 19, 2012 Category: Anesthesiology Authors: Neelankavil J, Howard-Quijano K, Hsieh TC, Ramsingh D, Scovotti JC, Chua JH, Ho JK, Mahajan A Tags: Anesth Analg Source Type: research

Volumetric Three-Dimensional Ultrasound Imaging of the Anatomy Relevant for Thoracic Paravertebral Block.
Conclusions:Volumetric 3D ultrasound imaging of the thoracic paravertebral space is feasible and provides more detailed spatial anatomical information than 2D ultrasound imaging. PMID: 22822198 [PubMed - as supplied by publisher]
Source: Anesthesia and Analgesia - July 19, 2012 Category: Anesthesiology Authors: Karmakar MK, Li X, Li J, Hadzic A Tags: Anesth Analg Source Type: research

Advances in Molecular Genetics of Hirschsprung's Disease.
Abstract Hirschsprung's disease (HSCR) is a developmental disorder of the enteric nervous system, which occurs due to the failure of neural crest cells to fully colonize the gut during embryonic development. It is characterized by the absence of the enteric ganglia in a variable length of the intestine. Substantial progress has been made in understanding the genetic basis of HSCR with the help of advanced genetic analysis techniques and animal models. More than 11 genes have been found to be involved in the pathogenesis of HSCR. The RET gene is the most important susceptibility gene involved in HSCR with both codin...
Source: Anatomical Record - July 19, 2012 Category: Anatomy Authors: Pan ZW, Li JC Tags: Anat Rec (Hoboken) Source Type: research

Initial clinical experience with the coherex FlatStent™ and FlatStent™ EF PFO closure system for in‐tunnel PFO closure: Results of the Coherex‐EU study
Conclusion:This initial study of the Coherex FlatStent/FlatStent EF PFO Closure System demonstrated the potential for in‐tunnel PFO closure. The in‐tunnel Coherex FlatStent EF may offer an alternative to septal repair devices for PFO closure in appropriately selected patients; however, further investigation will be necessary to establish the best use of this device. © 2012 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - July 19, 2012 Category: Cardiovascular & Thoracic Surgery Authors: Horst Sievert, Nina Wunderlich, Isabel Reiffenstein, Peter Ruygrok, Eberhard Grube, Lutz Buellesfeld, Bernhard Meier, Joachim Schofer, David Muller, Randall K. Jones, Linda Gillam Source Type: research

Observations on torquaratorid acorn worms (Hemichordata, Enteropneusta) from the North Atlantic with descriptions of a new genus and three new species
AbstractEnteropneusts in the family Torquaratoridae were imaged using still and video cameras in the deep North Atlantic and then collected by remotely operated vehicles. From this material, we describe Yoda purpurata n. gen, n. sp., Tergivelum cinnabarinum n. sp., and Allapasus isidis n. sp. Individuals of the first two species were browsing completely exposed on the sea floor, whereas the specimen of the last species was encountered floating ~1 m above the sea floor. Living specimens of Y. purpurata were 12–19 cm long and had a dark reddish‐purple proboscis, collar, and genital wings (folded dorsally over the anter...
Source: Invertebrate Biology - July 19, 2012 Category: Biology Authors: Imants G. Priede, Karen J. Osborn, Andrey V. Gebruk, Dan Jones, David Shale, Antonina Rogacheva, Nicholas D. Holland Tags: Original Article Source Type: research

Global and regional alterations of hippocampal anatomy in long‐term meditation practitioners
AbstractStudies linking meditation and brain structure are still relatively sparse, but the hippocampus is consistently implicated as one of the structures altered in meditation practitioners. To explore hippocampal features in the framework of meditation, we analyzed high‐resolution structural magnetic resonance imaging data from 30 long‐term meditators and 30 controls, closely matched for sex, age, and handedness. Hippocampal formations were manually traced following established protocols. In addition to calculating left and right hippocampal volumes (global measures), regional variations in surface morphology were d...
Source: Human Brain Mapping - July 19, 2012 Category: Neurology Authors: Eileen Luders, Paul M. Thompson, Florian Kurth, Jui‐Yang Hong, Owen R. Phillips, Yalin Wang, Boris A. Gutman, Yi‐Yu Chou, Katherine L. Narr, Arthur W. Toga Tags: Research Article Source Type: research

Combined 3D rotational fluoroscopic-MRI cloacagram procedure defines luminal and extraluminal pelvic anatomy prior to surgical reconstruction of cloacal and other complex pelvic malformations
Conclusion  This novel form of preoperative imaging results in excellent delineation channel/fistula lengths, luminal anatomy, and extra-luminal soft tissue structures to aid in operative planning. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00383-012-3122-6Authors Marcus D. Jarboe, Section of Pediatric Surgery, Department of Surgery, C.S. Mott Children’s Hospital, University of Michigan, 1540 E. Hospital Dr., SPC 4211, Ann Arbor, MI 48109-4211, USADaniel H. Teitelbaum, Section of Pediatric Surgery, Department of Surgery, C.S. Mott Children’s Hospital, University of ...
Source: Pediatric Surgery International - July 18, 2012 Category: Surgery Tags: Pediatric Surgery International Source Type: research

Development of the subcortical brain structures in the second trimester: assessment with 7.0-T MRI
Conclusion  Development of the subcortical brain structures during 12–22 weeks GA could be displayed with 7.0-T MRI. The measurement provides significant reference beneficial to the clinical evaluation of fetal brain development. Content Type Journal ArticleCategory Paediatric NeuroradiologyPages 1-7DOI 10.1007/s00234-012-1069-xAuthors Haiwei Meng, Research Center for Sectional and Imaging Anatomy, School of Medicine, Shandong University, 44 Wen-hua Xi Road, Jinan, Shandong Province, People’s Republic of China 250012Zhonghe Zhang, Department of Medical Imaging, Provincial Hospital Affiliated ...
Source: Neuroradiology - July 18, 2012 Category: Radiology Tags: Neuroradiology Source Type: research

Cancer cachexia alters intracellular surfactant metabolism but not total alveolar surface area
Abstract  Dyspnoea is frequently observed in cancer cachectic patients. Little is known whether this is accompanied by structural or functional alterations of the lung. We hypothesized that in analogy to calorie restriction cancer cachexia leads to loss of alveolar surface area and surfactant. Mice were subjected to subcutaneous injection of Lewis lung carcinoma cells (tumour group, TG) or saline (control group, CG). Twenty-one days later blood samples and the lungs were taken. Using design-based stereology, the alveolar surface area and the lamellar body (Lb) content were quantified. Messenger RNA expression...
Source: Histochemistry and Cell Biology - July 18, 2012 Category: Biomedical Science Tags: Histochemistry and Cell Biology Source Type: research

Three-dimensional shape differences in the bony pelvis of women with pelvic floor disorders
Conclusions  Pelvic shape in women with PFDs is characterized by the proportional mediolateral enlargement of the pelvic midplane and ischial eversion near the subpubic arch, consistent with inferolateral migration of the attachment points for the levator ani and correspondingly lateral displacement. These movements may result in increased strain on the pelvic floor’s muscular and connective tissues, increasing the risk of failure over a woman’s lifetime. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s00192-012-1876-yAuthors Kirsten M. Brown, Department of Anatomy and...
Source: International Urogynecology Journal - July 18, 2012 Category: OBGYN Tags: International Urogynecology Journal Source Type: research

Neural Stem Cells Enhance Nerve Regeneration after Sciatic Nerve Injury in Rats
Abstract  With the development of tissue engineering and the shortage of autologous nerve grafts in nerve reconstruction, cell transplantation in a conduit is an alternative strategy to improve nerve regeneration. The present study evaluated the effects and mechanism of brain-derived neural stem cells (NSCs) on sciatic nerve injury in rats. At the transection of the sciatic nerve, a 10-mm gap between the nerve stumps was bridged with a silicon conduit filled with 5 × 105 NSCs. In control experiments, the conduit was filled with nerve growth factor (NGF) or normal saline (NS). The functional and morpholog...
Source: Molecular Neurobiology - July 18, 2012 Category: Neurology Tags: Molecular Neurobiology Source Type: research

Quadrifascicular?
Two articles in this issue of the Journal review the complex anatomy of the left ventricular conducting system and the various electrocardiograms (ECGs) and vectorcardiograms (VCGs) resulting from dysfunction of various branches, divisions, or fascicles of the left bundle branch. These reviews and accompanying editorials present the several resulting problems in ECG diagnosis and terminology, which confront cardiologists on a daily basis.
Source: Journal of Electrocardiology - July 18, 2012 Category: Cardiology Authors: Irwin Hoffman Tags: Editorial Source Type: research

The distribution of HCN2-positive cells in the gastrointestinal tract of mice.
This study investigated the distribution of HCN2-positive cells in the mouse GI tract using immunohistochemistry. To identify the nature of these HCN2 cells, anti-ChAT and anti-Kit antibodies were used to co-label neurons and the interstitial cells of Cajal (ICCs), respectively. Additionally, differences in the distribution of HCN2-positive cells within the GI tract were also analyzed. Our results showed that HCN2 channels were mainly located within the myenteric neurons of the enteric nervous system in the GI tract. Double-staining revealed that HCN2-positive neurons were labeled by ChAT, indicating that these HCN2-positi...
Source: Journal of Anatomy - July 18, 2012 Category: Anatomy Authors: Yang S, Xiong CJ, Sun HM, Li XS, Zhang GQ, Wu B, Zhou DS Tags: J Anat Source Type: research

Paul Shankman. The Trashing of Margaret Mead: Anatomy of an Anthropological Controversy. Madison, WI: University of Wisconsin Press, 2009. 299 pp. $29.95 (paperback). ISBN‐13: 978‐029923454‐6.
Source: Journal of the History of the Behavioral Sciences - July 18, 2012 Category: Psychiatry & Psychology Authors: Gerald Sullivan Tags: Book Review Source Type: research

Greater saphenous vein evaluation from computed tomography angiography as a potential alternative to conventional ultrasonography
Conclusions: Indirect venography by CTA correlates well with US for GSV mapping in the lower extremity and offers significant reduction in imaging-related preoperative charges. CTA is sensitive and accurate for detecting GSVs that are appropriate for bypass. Furthermore, CTA allows AP and lateral evaluation of the GSV throughout its anatomic course. As CTA is often performed prior to arterial bypass, indirect evaluation of the GSV using preoperative CTA should be considered a promising alternative to the use of US.
Source: Journal of Vascular Surgery - July 17, 2012 Category: Surgery Authors: William F. Johnston, Jonathan K. West, Damien J. LaPar, Kenneth J. Cherry, John A. Kern, Margaret C. Tracci, Gorav Ailawadi, Gilbert R. Upchurch Tags: Clinical research studies Source Type: research

Professor Emeritus Phillip Vallentine Tobias (1925–2012)
Source: Clinical Anatomy - July 17, 2012 Category: Anatomy Authors: Beverley Kramer Tags: In Remembrance Source Type: research

The sinuvertebral nerves at the craniovertebral junction: A microdissection study
AbstractBogduk et al. (1988, Spine 13:2–8) noted that the joints and ligaments at the cervico‐occipital region are susceptible to whiplash injury. The upper three cervical sinuvertebral nerves (SVNs) at the craniovertebral junction (CVJ) are thought to be responsible for mediating pain from the ligaments, dura mater, and soft tissues of the posterior cranial fossa and upper cervical column. The purpose of this study was to describe in detail the origin and course of the SVNs at C0–C1, C1–C2, and C2–C3 intervertebral levels and their anterior intraspinal distribution. A sample comprising 10 adult, 12 fetal (crown ...
Source: Clinical Anatomy - July 17, 2012 Category: Anatomy Authors: C. Rennie, M.R. Haffajee, M.A.A. Ebrahim Tags: Original Communication Source Type: research

Macroscopic and microscopic features of the mandibular condyle in autopsied elderly individuals
In this study, 144 condyles from 78 cadavers (40 men, 38 women; age at death: >70 years) were investigated. The macroscopic shapes of the condyles were classified from posterior and lateral views into four types: convex, flattened, angled, and irregular. Of the 144 condyles, 25 were investigated microscopically. On macroscopic examination, in both posterior and lateral views, convex‐type condyles were most frequently observed. Most posterior convex‐type condyles were also categorized as the lateral convex type. On histological examination, we observed an increase in cartilage cells (7 condyles, 28%), a decrease in c...
Source: Clinical Anatomy - July 17, 2012 Category: Anatomy Authors: Mitsuyoshi Nakai, Masato Abe, Akihiro Miyazaki, Mineko Fujimiya, Hiroyoshi Hiratsuka Tags: Original Communication Source Type: research

4D blood flow visualization fusing 3D and 4D MRA image sequences
Conclusion:The presented method enables an improved combined representation of blood flow and anatomy while reducing the time needed for clinical rating. J. Magn. Reson. Imaging 2012;36:443–453. © 2012 Wiley Periodicals, Inc.
Source: Journal of Magnetic Resonance Imaging - July 17, 2012 Category: Radiology Authors: Nils Daniel Forkert, Jens Fiehler, Till Illies, Dietmar P.F. Möller, Heinz Handels, Dennis Säring Tags: Cover Image Source Type: research

Aberrant Right Subclavian Artery in Blunt Aortic Injury: Implication for Treatment and Review of the Literature
We report the case of a man with an ARSA who suffered from BAI. An initial conservative treatment with delayed open repair was chosen. A review of the published literature with discussion of the case is presented. The presence of an ARSA in patients with BAI can be considered a poor anatomy for endovascular repair, and suitable patients may benefit from delayed open repair.
Source: Annals of Vascular Surgery - July 16, 2012 Category: Surgery Authors: Giovanni Coppi, Yamume Tshomba, Daniele Psacharopulo, Enrico Maria Marone, Roberto Chiesa Tags: Case Report Abstracts Source Type: research

Surgical management of portal hypertension in children
The management of children with portal hypertension has dramatically changed during the past decade, with an improvement in outcome. This has been achieved by improved efficiency of endoscopic variceal control and the success of liver transplantation. Emergency surgical shunt procedures are rarely required, with acute bleeding episodes generally controlled endoscopically or, occasionally in adults, by interventional radiological procedures. Portosystemic shunts may be considered as a bridge to transplant in adults but are rarely used in this context in children. Nontransplant surgery or radiological interventions may still...
Source: Seminars in Pediatric Surgery - July 16, 2012 Category: Pediatrics Authors: Jean de Ville de Goyet, Giuseppe D'Ambrosio, Chiara Grimaldi Source Type: research

Martius flap: historical and anatomical considerations
Abstract  Martius flap is used infrequently by urologists and coloproctologists for repair of fistulae in the perineal region, and is usually missing from the reconstructive palette of plastic surgeons. There is a considerable confusion regarding what the Martius flap contains. It may contain skin, fat, or muscle from the labium major region. In the original description, Heinrich Martius applied the bulbocavernous/bulbospongious muscle for repair of urethra-vaginal fistula. Nowadays, what is known as Martius flap contains the more voluminous labium major fat pad mostly independent of the above muscle. In cada...
Source: European Journal of Plastic Surgery - July 16, 2012 Category: Cosmetic Surgery Tags: European Journal of Plastic Surgery Source Type: research

Co-localisation of Kir4.1 and AQP4 in rat and human cochleae reveals a gap in water channel expression at the transduction sites of endocochlear K+ recycling routes
This study describes the subcellular co-localisation of the Kir4.1 K+ channel (Kir4.1) and the aquaporin-4 water channel (AQP4) in SCs, on the basis of immunohistochemical double-labelling experiments in rat and human cochleae. The results of this study reveal the expression of Kir4.1 in the basal or basolateral membranes of the SCs in the sensory domain of the organ of Corti that are adjacent to hair cells and in the non-sensory domains of the inner and outer sulci that abut large extracellular fluid spaces. The SCs of the inner sulcus (interdental cells, inner sulcus cells) and the outer sulcus (Hensen’s cells,...
Source: Cell and Tissue Research - July 16, 2012 Category: Cytology Tags: Cell and Tissue Research Source Type: research

Craniofacial surgical strategies for the correction of pneumosinus dilatans frontalis
Conclusion: A variety of surgical procedures have been proposed for the correction of the pneumosinus dilatans frontalis. The craniofacial approach is advocated to reproduce the normal anatomy of the forehead in the upper part, the supraorbital rim and glabellar area.
Source: Journal of Cranio-Maxillofacial Surgery - July 16, 2012 Category: ENT & OMF Authors: Manlio Galiè, Giuseppe Consorti, Luigi C. Clauser, Henry K. Kawamoto Source Type: research

Total adhesions treated by hysteroscopy: must we stop at two procedures?
Conclusion(s): The number of hysteroscopic procedures envisioned to treat Asherman syndrome should not be a limiting factor. It is appropriate to treat women, especially those younger than 35 years, until uterine anatomy permits the visualization of both ostia.
Source: Fertility and Sterility - July 16, 2012 Category: Reproduction Medicine Authors: Hervé Fernandez, Sarah Peyrelevade, Guillaume Legendre, Erika Faivre, Xavier Deffieux, André Nazac Tags: Gynecology and menopause Source Type: research

Neurosonoembryology by three-dimensional ultrasound
Summary: High-resolution three-dimensional (3D) ultrasound has enabled the visualization of small embryos and fetuses, and embryology in vivo – ‘3D sonoembryology’ – has been established based on conventional embryology. Recently developed imaging techniques allow the definition of in-vivo anatomy including visualization of the embryonic circulation and dynamic features that could not be characterized in fixed specimens. Three-dimensional ultrasound has facilitated increasingly accurate and objective prenatal diagnoses of cranium bifidum/spina bifida, holoprosencephaly and associated anomalies in the first trimest...
Source: Seminars in Fetal and Neonatal Medicine - July 16, 2012 Category: Perinatology & Neonatology Authors: Ritsuko K. Pooh Source Type: research

Commentary on ‘AAA with a Challenging Neck: Early Outcomes Using the Endurant Stent-graft System’
Latest generation devices for endovascular aortic repair (EVAR) are raising an increasing interest due to the possibility to extend effective treatment to aneurysm anatomies judged unfeasible by endovascular route in the past. The Endurant Medtronic stent graft has been introduced as an improved device to manage abdominal aortic aneurysms (AAAs) with difficult necks. In this issue of EJVES, Setacci et al. showed that the Endurant can also work well on really adverse neck anatomies using compelled off-label indications such as short neck length 60° neck angle, significant thrombus or conical neck. Despite the adverse anat...
Source: European Journal of Vascular and Endovascular Surgery - July 16, 2012 Category: Surgery Authors: E. Cieri, P. De Rango Tags: Invited Commentary Source Type: research

Cardiac specific ATP-sensitive K+ channel (KATP) overexpression results in embryonic lethality
In conclusion, KATP channels are present and active in embryonic myocytes, and overexpression causes in utero heart failure and results in embryonic lethality. These results suggest that the KATP channel may have an important physiological role during early cardiac development.Highlights: ► KATP currents are detected in embryonic cardiomyocytes since early cardiac development. ► Embryos overexpressing KATP demonstrate normal cardiac looping pattern. ► Transgenic mice overexpressing KATP channel subunits demonstrate embryonic lethality. ► The embryonic lethality of the KATP overexpressing embryos is a result of in utero heart failure.
Source: Journal of Molecular and Cellular Cardiology - July 16, 2012 Category: Cytology Authors: Amir Toib, Hai Xia Zhang, Thomas J. Broekelmann, Krzysztof L. Hyrc, Qiusha Guo, Feng Chen, Maria S. Remedi, Colin G. Nichols Tags: Regular Articles Source Type: research

MR Imaging of the Temporomandibular Joint
MR imaging allows detailed evaluation of temporomandibular (TMJ) anatomy because of its inherent tissue contrast and high resolution. Joint biomechanics can be assessed through imaging patients in the closed and open jaw positions. Despite the accuracy of MR imaging in detecting disc position, results must be interpreted together with clinical findings, because an anteriorly displaced disc can be seen in up to one-third of asymptomatic patients, and a normal disc position can be seen in up to one-quarter of symptomatic patients. Interpretation of MR imaging requires knowledge of the normal anatomy and an understanding of n...
Source: Magnetic Resonance Imaging Clinics of North America - July 16, 2012 Category: Radiology Authors: Ashley Aiken, Gary Bouloux, Patricia Hudgins Source Type: research

Ultrastructural and Morphological Characteristics of Human Anterior Cruciate Ligament and Hamstring Tendons.
This study compared the anatomy of normal human ACL and hamstring tendons, which may provide a standard for evaluating hamstring tendons grafts after ACL reconstruction and may facilitate the application of hamstring tendons in clinical applications. Anat Rec, 2012. © 2012 Wiley Periodicals, Inc. PMID: 22807249 [PubMed - as supplied by publisher]
Source: Anatomical Record - July 16, 2012 Category: Anatomy Authors: Zhu J, Zhang X, Ma Y, Zhou C, Ao Y Tags: Anat Rec (Hoboken) Source Type: research

Three-Dimensional Analysis of the Islet Vasculature.
Abstract The pancreatic islets of Langerhans are highly vascularized structures scattered throughout the pancreas that contain a capillary network 5-10 times denser than that of the exocrine pancreas. A simple method for three-dimensional (3D) analysis of this intricate intraislet vasculature has been difficult because of the intrinsic opacity of the pancreas. We developed a whole-mount imaging technique that allows relatively easy visualization of the islet vasculature. In combination with confocal microscopy and the use of 3D imaging software, we were able to readily reconstruct the 3D architecture of an islet, a...
Source: Anatomical Record - July 16, 2012 Category: Anatomy Authors: El-Gohary Y, Sims-Lucas S, Lath N, Tulachan S, Guo P, Xiao X, Welsh C, Paredes J, Wiersch J, Prasadan K, Shiota C, Gittes GK Tags: Anat Rec (Hoboken) Source Type: research

Cortical Bone Response to the Presence of Load-Bearing Percutaneous Osseointegrated Prostheses.
Abstract Although the current percutaneous osseointegrated (OI) prosthetic attachment systems are novel clinical treatments for patients with limb loss, there have only been limited translational studies undertaken to date. To bridge this knowledge gap, from a larger study group of 86 animals that were implanted with a novel percutaneous OI implant construct, 33 sheep were randomly selected from the 0-, 3-, 6-, 9- and 12-month groups for histomorphometric analyses of periprosthetic cortical bone tissue. At necropsy, implanted and nonimplanted limbs were harvested and processed for the evaluation of cortical bone po...
Source: Anatomical Record - July 16, 2012 Category: Anatomy Authors: Jeyapalina S, Beck JP, Bachus KN, Bloebaum RD Tags: Anat Rec (Hoboken) Source Type: research