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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 24.
The inter-optic course of a unique precommunicating anterior cerebral artery with aberrant origin of an ophthalmic artery: an anatomic case report
Conclusion To the best of our knowledge, this is a very rare illustrated case of an inter-optic course of a unique precommunicating anterior cerebral artery with aberrant origin of an ophthalmic artery. Content Type Journal ArticleCategory Anatomic VariationsPages 1-3DOI 10.1007/s00276-012-1028-6Authors Pierre Hannequin, Department of Neurosurgery, University of Amiens, CHU AMIENS Nord, Place Victor Pauchet, 80054 AMIENS Cedex 1, FranceJohann Peltier, Department of Neurosurgery, University of Amiens, CHU AMIENS Nord, Place Victor Pauchet, 80054 AMIENS Cedex 1, FranceChristophe Destrieux, Department o...
Source: Surgical and Radiologic Anatomy - September 30, 2012 Category: Anatomy Tags: Surgical and Radiologic Anatomy Source Type: research
New to Nature No 86: Discus rupivagus
A snail from the Canary Islands catches the eye not just for its priapic anatomy, but also for links it reveals with other islandsA new land snail of the family Discidae from the Canary Islands makes it easy to understand the popularity of shell collecting.Its compressed and spiralled form is at once intricate, delicate and detailed. Discus rupivagus differs, in part, from species found in the Palaearctic and Nearctic regions by its "large" (up to 13mm), excessively flattened, sharply keeled and widely umbilicated shell. Unlike most other species of the genus which have strong and regular radial ribs, the shell of D r...
Source: Guardian Unlimited Science - September 29, 2012 Category: Science Authors: Quentin Wheeler Tags: Evolution World news Features Animals The Observer Zoology Environment Science Wildlife Source Type: news
Morphometric evaluation of parasagittal venous anatomy for intracranial approaches: a cadaveric study.
CONCLUSION: Knowing details of anatomic structures of SSS and venous structures draining into it may protect the patients from many surgical complications. SSS and related structures with surgical landmarks are valuable for neurosurgeons. PMID: 23015329 [PubMed - in process]
Source: Turkish Neurosurgery - September 29, 2012 Category: Neurosurgery Authors: Sayhan S, Guvencer M, Ozer E, Arda MN Tags: Turk Neurosurg Source Type: research
Anatomy in undergraduate medical education: A survey of student perceptions
Aims: A shift away from cadaveric dissection in UK medical curricula has emerged. The impacts of this on future anatomical and surgical competences are unclear. We assessed student perceptions to different methods of Anatomy teaching.
Source: International Journal of Surgery - September 28, 2012 Category: Surgery Authors: S.J. Chapman, A.R. Hakeem, G. Marangoni, K.R. Prasad Tags: Abstracts from the Assocation of Surgeons in Training Conference Source Type: research
Surgical simulation in anatomy education: An untapped resource?
We present the first prospective cohort-controlled trial to evaluate the use of an ENT surgical simulator in teaching temporal bone anatomy by designing an interactive simulator-based module and a non-interactive self-directed module.
Source: International Journal of Surgery - September 28, 2012 Category: Surgery Authors: Ussamah El-khani, Asit Arora, Jean Nehme, Arvind Singh, Shamim Toma, Ceri Davies Tags: Abstracts from the Assocation of Surgeons in Training Conference Source Type: research
Disordered sleep physiology in children presenting for primary cleft repair. The use of sleep study results to guide preoperative respiratory intervention and plan the timing of surgical cleft repair
This study investigates breathing patterns indicative of the need for respiratory intervention in patients undergoing primary repair.
Source: International Journal of Surgery - September 28, 2012 Category: Surgery Authors: Justice Reilly, Craig Russell, Neil Gibson, Tony Moores, Arup Ray, Mark Devlin, David Wynne Tags: Abstracts from the Assocation of Surgeons in Training Conference Source Type: research
Calot's triangle. A common misconception of basic anatomy
This study aimed to review the medical literature on the description of CT.
Source: International Journal of Surgery - September 28, 2012 Category: Surgery Authors: Darmarajah Veeramootoo, Amanda Bond, Anthony Miles, Krishna Singh Tags: Abstracts from the Assocation of Surgeons in Training Conference Source Type: research
Skin reference point for the zygomatic branch of the facial nerve innervating the orbicularis oculi muscle (anatomical study)
Conclusions The simplicity and reliability of this landmark is important in clinical practice and has numerous potential applications in surgery for rehabilitation of facial paralysis associated with VII healthy and VII affected neurorraphies, in facial paresis for superneurotizations and in traumatology. Content Type Journal ArticleCategory Anatomic Bases of Medical, Radiological and Surgical TechniquesPages 1-4DOI 10.1007/s00276-012-1023-yAuthors A. Chatellier, Department of Maxillo-facial and Plastic Surgery, CHU Caen, Avenue de la Côte de Nacre, 14033 Caen Cedex, FranceD. Labbé, Department of ...
Source: Surgical and Radiologic Anatomy - September 28, 2012 Category: Anatomy Tags: Surgical and Radiologic Anatomy Source Type: research
Attachments of separate small bundles of human posterior cruciate ligament: an anatomic study
Conclusion Small bundles of PCL showed a relatively layered arrangement between tibial and femoral attachments. Therefore, anatomic PCL reconstruction cannot be completed simply performed merely with straight bundles and circular bone tunnels. Content Type Journal ArticleCategory KneePages 1-7DOI 10.1007/s00167-012-2224-yAuthors Daisuke Hatsushika, Section of Orthopedic Surgery, Graduate School, Tokyo Medical and Dental University, Tokyo, JapanAkimoto Nimura, Unit of Clinical Anatomy, Graduate School, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519 JapanTomoyuki Mochiz...
Source: Knee Surgery, Sports Traumatology, Arthroscopy - September 28, 2012 Category: Orthopaedics Tags: Knee Surgery, Sports Traumatology, Arthroscopy Source Type: research
mTORC1 is a target of nordihydroguaiaretic acid to prevent breast tumor growth in vitro and in vivo
In this study, we identified mammalian target of rapamycin complex 1 (mTORC1) as a target of NDGA both in cultured breast cancer cells and in xenograft models. NDGA effectively inhibited basal level of mTORC1 but not mTORC2 activity in breast cancer cell lines. NDGA also suppressed mTORC1 downstream signaling such as expression of cyclin D1, hypoxia-inducible factor-α and VEGF, and prevented proliferation in breast cancer cells. Although NDGA stimulated AMP-activated protein kinase (AMPK)/tuberous sclerosis complex 2 (TSC2) signaling, which negatively regulates mTORC1, AMPK and TSC2 deletion could not diminish the in...
Source: Breast Cancer Research and Treatment - September 28, 2012 Category: Cancer & Oncology Tags: Breast Cancer Research and Treatment Source Type: research
Evolution of customization design for total knee arthroplasty
Abstract Total Knee Arthroplasty (TKA) is a highly successful surgical procedure with more than 600,000 TKA’s performed annually in the US. Interest in improving surgical outcomes has led to improvements in surgical technique, instrumentation, and implant design. Computer navigation and robotic systems were introduced to further refine the mechanical alignment of joint replacement procedures. The cost to implement some of these technologies and the additional time required in the operating room to utilize these developments has limited the acceptance of them broadly. The introduction of custom instrumentat...
Source: Current Reviews in Musculoskeletal Medicine - September 28, 2012 Category: Orthopaedics Tags: Current Reviews in Musculoskeletal Medicine Source Type: research
Neferine Inhibits the Upregulation of CCL5 and CCR5 in Vascular Endothelial Cells During Chronic High Glucose Treatment
Abstract We investigated whether the expressions of CCL5 and CCR5 participate in dysfunctional changes in human umbilical vein endothelial cells (HUVECs) induced by chronic high glucose treatment and examined whether neferine exerts its therapeutic effects by blocking the development of dysfunctional vascular endothelium. HUVECs were cultured with control or high concentrations of glucose in the absence or presence of neferine for 5 days. Nitric acid reductase method was used to detect the concentration of nitric oxide (NO) released into culture media. The level of intracellular reactive oxygen species ...
Source: Inflammation - September 28, 2012 Category: Biomedical Science Tags: Inflammation Source Type: research
Med Sci Monit 2012; 18(10):BR419-426 "Quantitative anatomy of the growing abdominal aorta in human fetuses: An anatomical, digital and statistical study"
Conclusions: There are no significant differences between males and females for morphometric parameters of the abdominal aorta. The abdominal aorta grows linearly in both length and diameters, and parabolically in volume. These detailed morphometric data of the abdominal aorta provide a database for intra-uterine echographic examinations in the early diagnosis, monitoring and management of aorto-iliac malformations.
Source: Medical Science Monitor - September 28, 2012 Category: Research Tags: Original article Source Type: research
A new species of Asthenocotyle Robinson, 1961 (Monogenea: Microbothriidae), a skin parasite of the great lanternshark Etmopterus princeps Collett from the Azores, with a redescription of A. kaikourensis Robinson, 1961 and observations on A. taranakiensis Beverley-Burton, Klassen & Lester, 1987.
A new species of Asthenocotyle Robinson, 1961 (Monogenea: Microbothriidae), a skin parasite of the great lanternshark Etmopterus princeps Collett from the Azores, with a redescription of A. kaikourensis Robinson, 1961 and observations on A. taranakiensis Beverley-Burton, Klassen & Lester, 1987. Syst Parasitol. 2012 Oct;83(2):145-58 Authors: Kearn GC, Whittington ID, Thomas P Abstract Asthenocotyle azorensis n. sp. (Monogenea: Microbothriidae) is described from the dermal denticles of the great lanternshark Etmopterus princeps Collett off the Azores. The type-species of the genus, A. kaikourensis Robinso...
Source: Systematic Parasitology - September 28, 2012 Category: Parasitology Authors: Kearn GC, Whittington ID, Thomas P Tags: Syst Parasitol Source Type: research
Blood Test Developed That Accurately Detects Early Stages Of Lung, Breast Cancer In Humans
Researchers at Kansas State University have developed a simple blood test that can accurately detect the beginning stages of cancer. In less than an hour, the test can detect breast cancer and non-small cell lung cancer -- the most common type of lung cancer -- before symptoms like coughing and weight loss start. The researchers anticipate testing for the early stages of pancreatic cancer shortly. The test was developed by Stefan Bossmann, professor of chemistry, and Deryl Troyer, professor of anatomy and physiology...
Source: Health News from Medical News Today - September 28, 2012 Category: Consumer Health News Tags: Lung Cancer Source Type: news
Galnt3 deficiency disrupts acrosome formation and leads to oligoasthenoteratozoospermia
Abstract Galnt3 belongs to the GalNAc transferase gene family involved in the initiation of mucin-type O-glycosylation. Male Galnt3-deficient (Galnt3 −/−) mice were infertile, as previously reported by Ichikawa et al. (2009). To investigate the involvement of Galnt3 in spermatogenesis, we examined the differentiation of germ cells in Galnt3 −/− mice. Galnt3 mRNA was most highly expressed in testis, and Galnt3 protein was localized in the cis-medial parts of the Golgi stacks of spermatocytes and spermatids in the seminiferous tubules. Spermatozoa in Galnt3 −/− mice were rare and immotile, and mo...
Source: Histochemistry and Cell Biology - September 28, 2012 Category: Biomedical Science Tags: Histochemistry and Cell Biology Source Type: research
Evidence-Based Practice to Improve Outcomes of Anterior Cruciate Ligament Reconstruction
Recent studies of anatomic anterior cruciate ligament (ACL) reconstruction have considered native knee anatomy and biomechanical function, and emphasized the long-term goals of protecting knee health and preventing the development of symptomatic ACL-deficient degenerative arthrosis. Validated and reproducible examination maneuvers are necessary for accurate diagnosis and appraisal of surgical interventions. Appropriately powered expertise-based trials should be emphasized to minimize bias, enhance validity, and reduce crossover. Best practice rehabilitation protocols can guide postoperative care while minimizing heterogene...
Source: Clinics in Sports Medicine - September 28, 2012 Category: Sports Medicine Authors: O.R. Ayeni, N. Evaniew, R. Ogilvie, D.C. Peterson, M.R. Denkers, M. Bhandari Source Type: research
Air in the main pancreatic duct: A case of innocent air.
We report a case of "innocent" air found incidentally in the main pancreatic duct. To our knowledge, this is only the third such case reported. A 54-year-old woman presented with hemoptysis that had lasted for 3 d. She underwent a chest computed tomography scan, which revealed not only focal bronchiectasis in the left lower lobe, but also air in the main pancreatic duct and dilatation of the common bile duct. She was managed conservatively for the hemoptysis and no further problems developed. She had no specific gastrointestinal symptoms and had no history of surgery or medication. Her laboratory parameters were normal. Ma...
Source: World Journal of Gastroenterology : WJG - September 28, 2012 Category: Gastroenterology Authors: Kim YJ, Kim HK, Cho YS, Kim SS, Chae HS, Kim SK, Kim ES, Lee SY Tags: World J Gastroenterol Source Type: research
Anterior longitudinal ligament release using the minimally invasive lateral retroperitoneal transpsoas approach: a cadaveric feasibility study and report of 4 clinical cases.
Conclusions This initial experience suggests that ALL release through the minimally invasive lateral retroperitoneal transpsoas approach may be feasible, allows for improvement of lumbar lordosis without the need of an open laparotomy/thoracotomy, and minimizes the tissue disruption and morbidity associated with posterior osteotomies. PMID: 23020211 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery.Spine - September 28, 2012 Category: Neurosurgery Authors: Deukmedjian AR, Le TV, Baaj AA, Dakwar E, Smith DA, Uribe JS Tags: J Neurosurg Spine Source Type: research
Tumor volume and subvolume concordance between FDG‐PET/CT and diffusion‐weighted MRI for squamous cell carcinoma of the cervix
Conclusion:Concordance of functional imaging was observed between FDG‐PET and DWI for cervical cancer. Tumor subvolumes with increased metabolic activity on FDG‐PET also have greater cell density by DWI. J. Magn. Reson. Imaging 2012. © 2012 Wiley Periodicals, Inc.
Source: Journal of Magnetic Resonance Imaging - September 28, 2012 Category: Radiology Authors: Jeffrey R. Olsen, Jacqueline Esthappan, Todd DeWees, Vamsi R. Narra, Farrokh Dehdashti, Barry A. Siegel, Julie K. Schwarz, Perry W. Grigsby Tags: Original Research Source Type: research
Zinc α2‐glycoprotein as a potential novel urine biomarker for the early diagnosis of prostate cancer
CONCLUSIONS • Urine detected ZAG showed promising results in the prediction of prostate cancer. • Further validation is required to establish ZAG as a novel biomarker.
Source: BJU International - September 28, 2012 Category: Urology & Nephrology Authors: Ioannis Katafigiotis, Stavros I. Tyritzis, Konstantinos G. Stravodimos, Christos Alamanis, Kitty Pavlakis, Antonia Vlahou, Manousos Makridakis, Amalia Katafigioti, Spiros D. Garbis, Constantinos A. Constantinides Source Type: research
Qualitative and Quantitative Anatomic Analysis of the Posterior Root Attachments of the Medial and Lateral Menisci
Conclusion: This quantitative study reproducibly identified the posterior root attachment centers of the medial and lateral menisci in relation to arthroscopically pertinent landmarks and guidelines. Clinical Relevance: These data can be directly applied to assist in anatomic meniscal root repairs.
Source: The American Journal of Sports Medicine - September 28, 2012 Category: Sports Medicine Authors: Johannsen, A. M., Civitarese, D. M., Padalecki, J. R., Goldsmith, M. T., Wijdicks, C. A., LaPrade, R. F. Tags: Knee, Meniscus, Operative research-article Source Type: research
Scapholunate Instability: Current Concepts in Diagnosis and Management
Injuries to the scapholunate joint are the most frequent cause of carpal instability and account for a considerable degree of wrist dysfunction, lost time from work, and interference with activities. Although it is insufficient to cause abnormal carpal posture or collapse on static radiographs, an isolated injury to the scapholunate interosseous ligament may be the harbinger of a relentless progression to abnormal joint mechanics, cartilage wear, and degenerative changes. Intervention for scapholunate instability is aimed at arresting the degenerative process by restoring ligament continuity and normalizing carpal kinemati...
Source: The Journal of Hand Surgery - September 27, 2012 Category: Surgery Authors: Alison Kitay, Scott W. Wolfe Tags: Current Concepts Source Type: research
Cardiac hybrid imaging guides revascularization prior to non-cardiac surgery
Cardiac hybrid imaging combines two imaging modalities: single-photon-emission computed tomography (SPECT) and positron emission tomography (PET) with coronary computed tomography angiography (CCTA) into a hybrid system. While SPECT-/or PET provides functional information on myocardial perfusion (MPI), CCTA depicts exact anatomy. This dual image or co-registration allows a comprehensive identification of functional information with its subtending coronary stenosis by CCTA.
Source: International Journal of Cardiology - September 27, 2012 Category: Cardiology Authors: Jelena-R. Ghadri, Tobias A. Fuchs, Christian Templin, Thomas F. Lüscher, Willibald Maier, Philipp A. Kaufmann Tags: Online Letters to the Editor Source Type: research
Histopathology of Scarring and Nonscarring Hair Loss
This article reviews the histologic findings of alopecia, preceded by a brief discussion of biopsy and processing techniques, the normal follicular anatomy and cycle, and expected findings in transverse sections. Subtle histologic abnormalities will be missed unless the normal follicular anatomy and follicular cycle, when viewed in transverse sections, are understood.
Source: Dermatologic Clinics - September 27, 2012 Category: Dermatology Authors: John M. Childs, Leonard C. Sperling Source Type: research
MR Imaging of the Brachial Plexus
This article discusses MR imaging evaluation of the brachial plexus, relevant anatomy, and common pathology with clinical and imaging details, indications for use of intravenous contrast, differential considerations, and diagnostic pitfalls.
Source: Magnetic Resonance Imaging Clinics of North America - September 27, 2012 Category: Radiology Authors: Igor Mikityansky, Eric L. Zager, David M. Yousem, Laurie A. Loevner Source Type: research
Contrast-Enhanced Cardiac Magnetic Resonance Imaging
Cardiac magnetic resonance (CMR) imaging has significantly evolved in the past decade and is well established in the evaluation of coronary artery disease (CAD). The evaluation of cardiac anatomy and contractility by high-resolution CMR can be improved by using intravenous administration of gadolinium-based contrast agents. Delayed enhancement CMR imaging has become the gold standard for quantification of myocardial viability in CAD. Contrast-enhanced CMR imaging may circumvent the need for endomyocardial biopsy or localize the involved regions, thereby improving the diagnostic yield of this invasive procedure. The applica...
Source: Magnetic Resonance Imaging Clinics of North America - September 27, 2012 Category: Radiology Authors: Carlos S. Restrepo, Sina Tavakoli, Alejandro Marmol-Velez Source Type: research
Contrast-Enhanced MR Imaging in Neuroimaging
MR imaging without and with gadolinium-based contrast agents (GBCAs) is an important imaging tool for defining normal anatomy and characteristics of lesions. GBCAs have been used in contrast-enhanced MR imaging in defining and characterizing lesions of the central nervous system for more than 20 years. The combination of unenhanced and GBCA-enhanced MR imaging is the clinical gold standard for the noninvasive detection and delineation of most intracranial and spinal lesions. MR imaging has a high predictive value that rules out neoplasm and most inflammatory and demyelinating processes of the central nervous system.
Source: Magnetic Resonance Imaging Clinics of North America - September 27, 2012 Category: Radiology Authors: Bum-soo Kim, Juan E. Gutierrez Source Type: research
Three-dimensional anatomy of the Ciona intestinalis tailbud embryo at single-cell resolution.
In this study, to understand comprehensively the anatomy of the tailbud embryo at single-cell-level, real microscopic image stacks of the tailbud embryo in Ciona intestinalis were reconstructed into a 3D computer model. This comprehensive 3D model of the ascidian tailbud embryo was based on real images of confocal laser scanning microscope (CLSM) and therefore, cell shape, location and cell arrangement reflect real geometries of the tailbud embryo. We found that the tailbud embryo consists of 1580 cells, including 836 epidermal cells, 228 cells in the central nervous system, 219 mesenchymal cells, four trunk ventral cells,...
Source: Developmental Biology - September 27, 2012 Category: Biology Authors: Nakamura MJ, Terai J, Okubo R, Hotta K, Oka K Tags: Dev Biol Source Type: research
[Epidemiology, anatomy, biomechanics and imaging of acromioclavicular joint injuries.]
In conclusion a biomechanically effective treatment of AC joint separation should analyze the individual instability pattern in the first step. Therefore, the radiological standard according to Rockwood should be supplemented by specific stress x-rays for quantification of dynamic horizontal AC joint instability. In the second step an adequate surgical treatment considering CC and AC stabilization should be performed meeting the individual patient requirements. PMID: 23011261 [PubMed - as supplied by publisher]
Source: Der Unfallchirurg - September 27, 2012 Category: Orthopaedics Authors: Wellmann M, Smith T Tags: Unfallchirurg Source Type: research
Walking on Eggshells: Anatomy of a Science Story
Today I have a piece in Slate’s Food section on what physics has to say about the proper way to crack an egg . Yeah, you heard me: there’s physics in the Food section, which is AS IT SHOULD BE, because physics is everywhere, y’all, and the folks at Slate totally get that. Naturally, there was a lot of stuff that didn’t make it into the final story, but that’s what the blog is for, right? And in addition to the usual outtakes, I thought it might be fun and instructive to give readers a peek into my writing process this time around.1. The Idea : what piqued my interest? There’s always a bi...
Source: Scientific American - Official RSS Feed - September 26, 2012 Category: Science Tags: More Science Source Type: research
The significance of tibial and common peroneal nerves in nerve blocks
Conclusion The results concerning the location of the TN and CPN at the popliteal crease offer a good guide to optimal nerve block. Content Type Journal ArticleCategory Original ArticlePages 1-5DOI 10.1007/s00276-012-1025-9Authors Je-Hun Lee, Department of Anatomy, College of Medicine, The Konyang University of Korea, Daejeon, KoreaBe-Na Lee, Department of Rehabilitation Medicine, College of Medicine, The Catholic University of Korea, Seoul, KoreaMichael Y. Lee, Department of Physical Medicine and Rehabilitation, School of Medicine, University of North Carolina, Chapel Hill, NC, USAXiaochun An, Departme...
Source: Surgical and Radiologic Anatomy - September 26, 2012 Category: Anatomy Tags: Surgical and Radiologic Anatomy Source Type: research
The influence of neural cell adhesion molecule isoform 140 on the metastasis of thyroid carcinoma
Abstract We previously showed that the preservation of neural adhesion molecule (NCAM) in differentiated thyroid carcinoma is an important indicator for a higher risk of distant metastasis. In the present study, we further demonstrated that forced NCAM-140 isoform expression in human thyroid cancer cells could lead to aggressive growth by enhancing migration and anchorage-independent growth, and exhibiting partial features of epithelial mesenchymal transition. More extensive distant metastasis was also noted in an animal xenograft model when NCAM-expressing thyroid cancer cells were introduced into mice intr...
Source: Clinical and Experimental Metastasis - September 26, 2012 Category: Cancer & Oncology Tags: Clinical and Experimental Metastasis Source Type: research
IgNobel Prize in Anatomy: I would know that butt anywhere
Today we present the IgNobel prize in ANATOMY, presented to de Waal and Pokorny. They were very pleased to win the IgNobel this year, noting especially that scientists always take themselves so seriously (sigh, yeah, we do), and it’s nice to have a little fun once in a while.de Waal and Pokorny. “Faces and behinds: chimpanzee sex preception” Advanced science letters, 2008. [More]
Source: Scientific American - Official RSS Feed - September 26, 2012 Category: Science Tags: Mind & Brain Source Type: research
Alarm!!! A UFO inside the heart
An 8-year-old asymptomatic child was referred for surgical repair of coronary sinus atrial septal defect resulting in significant left-to-right shunt and right chamber volume overload. The septal fenestration was located near to its drainage site into the right atrium. Due to this seemingly favourable anatomy, transcatheter closure of the septal defect was performed using an Amplatzer Septal Occluder device. The echocardiographic postprocedural evaluation imaged the occluding device almost perpendicular to the atrial septum, seemingly floating above the mitral valve orifice, like an alien spaceship inside the heart.
Source: Journal of Cardiovascular Medicine - September 26, 2012 Category: Cardiology Tags: Images in cardiovascular medicine Source Type: research
Ocular Anatomy, Ganglion Cell Distribution and Retinal Resolution of a Killer Whale (Orcinus orca)
Brain Behav Evol (DOI:10.1159/000341949)
Source: Brain, Behavior and Evolution - September 25, 2012 Category: Neurology Source Type: research
Endothelialization approaches for viable engineered tissues
Abstract One of the main limitation in obtaining thick, 3-dimensional viable engineered constructs is the inability to provide a sufficient and functional blood vessel system essential for the in vitro survival and the in vivo integration of the construct. Different strategies have been proposed to simulate the ingrowth of new blood vessels into engineered tissue, such as the use of growth factors, fabrication scaffold technologies, in vivo prevascularization and cell-based strategies, and it has been demonstrated that endothelial cells play a central role in the neovascularization process and in the control...
Source: Angiogenesis - September 25, 2012 Category: Molecular Biology Tags: Angiogenesis Source Type: research
Alleviation of autophagy by knockdown of Beclin-1 enhances susceptibility of hippocampal neurons to proapoptotic signals induced by amino acid starvation
This study examined the potential impact of knockdown of Beclin-1 in an autophagic response in HT22 neurons challenged with amino acid starvation (AAS). AAS exposure induced light chain-3 (LC-3)-immunopositive and monodansylcadaverine (MDC) fluorescent dye-labeled autophagosome formation in cell bodies as early as 3 h post-AAS in wild type cells. Elevated levels of the autophagosome-targeting LC3-II were also observed following AAS. In addition, neuronal death induced by AAS in HT22-cells led to a moderate activation of caspase-3, a slight upregulation of AIF and did not alter the HtrA2 levels. Autophagy inhibiti...
Source: Histochemistry and Cell Biology - September 25, 2012 Category: Biomedical Science Tags: Histochemistry and Cell Biology Source Type: research
Impact of video-endoscopy on the results of retrosigmoid-transmeatal microsurgery of vestibular schwannoma: prospective study
Abstract Endoscopy-assisted microsurgery represents modern trend of treatment of the cerebellopontine angle (CPA) pathologies including vestibular schwannoma (VS). Endoscopes are used in adjunct to microscope to achieve better functional results with less morbidity. Angled optics, magnification and illumination enable superior view in the operative field. Consecutive 89 patients with untreated unilateral sporadic vestibular schwannoma undergoing tumor resection via a retrosigmoid approach during 2008–2010 were prospectively analysed. Endoscopy-assisted microsurgical (EA-MS) removal was performed in 39 case...
Source: European Archives of Oto-Rhino-Laryngology - September 25, 2012 Category: ENT & OMF Tags: European Archives of Oto-Rhino-Laryngology Source Type: research
From external to internal auditory canal: surgical anatomy by an exclusive endoscopic approach
The objective of this study is to analyze the morphology, and surgical and anatomic findings of an exclusive endoscopic transcanal approach (EETA) to the IAC. Cadaveric dissections were performed on 11 temporal bones, approaching the internal auditory meatus directly through the external ear canal and avoiding mastoidectomy. In all cases, it was possible to dissect the internal carotid artery and jugular bulb with a 0° endoscope, and with good control of these two structures. The medial wall of the bony labyrinth guaranteed good landmarks for IAC dissection, such as the spherical recess, and the labyrinthine tract of...
Source: European Archives of Oto-Rhino-Laryngology - September 25, 2012 Category: ENT & OMF Tags: European Archives of Oto-Rhino-Laryngology Source Type: research
Exaggerated cue-induced reinstatement of cocaine seeking but not incubation of cocaine craving in a developmental rat model of schizophrenia
Conclusion These data confirm previous reports on enhanced resistance to extinction after NVHL and demonstrate that NVHL rats exhibit enhanced cue-induced reinstatement of cocaine seeking after extinction, a measure of drug relapse. Content Type Journal ArticleCategory Original InvestigationPages 1-7DOI 10.1007/s00213-012-2882-yAuthors Rose-Marie Karlsson, Department of Anatomy and Neurobiology, University of Maryland School of Medicine, 20 Penn St, HSFII, Room S251, Baltimore, MD 21201, USADaniel M. Kircher, Department of Anatomy and Neurobiology, University of Maryland School of Medicine, 20 Penn S...
Source: Psychopharmacology - September 25, 2012 Category: Psychiatry Tags: Psychopharmacology Source Type: research
Ocular Anatomy, Ganglion Cell Distribution and Retinal Resolution of a Killer Whale (Orcinus orca)
Brain Behav Evol (DOI:10.1159/000341949)
Source: Karger Publishers - September 25, 2012 Category: Cancer & Oncology Source Type: research
Malignant Tumors of the Skull Base
Skull base surgery for the treatment of malignant tumors has undergone substantial evolution over the past 50 years. Although resection of skull base tumors was sporadically attempted in the early part of the 20th century, it was not until the 1960s that interdisciplinary approaches combining expertise from neurosurgery, otolaryngology, and maxillofacial surgery facilitated the development of the field of skull base surgery. During the 1980s and 1990s, significant advancements in surgical and reconstructive techniques made oncologic resections at the skull base possible with acceptable morbidity. Concurrent advancements in...
Source: Neurosurgery Clinics of North America - September 25, 2012 Category: Neurosurgery Authors: Orin Bloch, Franco DeMonte Source Type: research
Blood Pressure and Blood Volume: Acute and Chronic Considerations in Hemodialysis.
Abstract Hypertension is highly prevalent yet poorly controlled in the majority of dialysis patients and represents a significant burden of disease, with rates of morbidity and mortality greater than those in the general population. In dialysis, blood volume plays a critical role in the pathogenesis of hypertension, with expansion of extracellular volume increasingly recognized as an independent risk factor for morbidity and mortality. Within the current paradigm of dialysis prescription the majority of patients remain chronically volume expanded. However, management of blood pressure and volume state is difficult ...
Source: Seminars in Dialysis - September 25, 2012 Category: Urology & Nephrology Authors: Lewicki MC, Kerr PG, Polkinghorne KR Tags: Semin Dial Source Type: research
Women’s speech is said to be more polite and considerate — the tag question is a case in point. It does not force agreement but rather is solicitous and democratic. However, the tag question can become a sort of Pandora's box. Now she has opened up the potential for denial of the request. Is there a place for the tag question?read more
Source: Psychology Today Work Center - September 24, 2012 Category: Psychiatry & Psychology Authors: Audrey Nelson, Ph.D. Tags: Gender Work anatomy audrey nelson phd case in point co author code switching collisions communication handbook denial distinction gender communication hesitancy ifs ands or buts insecurity lakoff pandora pfeiffer phd co Source Type: news
[18F]Fluorodeoxyglucose-PET/Computed Tomography, PET, and Magnetic Resonance Imaging: Normal Anatomy, Pitfalls, and Artifacts
Each anatomic region of the head and neck has physiologic variations that can mimic a primary tumor or lymph node. Many of these variations can be recognized as reflecting benign lymphoid, salivary, brown fat, and muscular activity. A few artifacts are related to computed tomography (CT) attenuation. A knowledge of tumor types and patterns of lymph node and metastatic spread helps categorize patterns as benign or malignant. The anatomic reference of CT helps solve many pitfalls. A recently introduced instrument, PET/magnetic resonance imaging, will face new pitfalls as its role in oncology is developed.
Source: PET Clinics - September 24, 2012 Category: Radiology Authors: Lina Mehta, Ryan T. Huber, Peter F. Faulhaber Source Type: research
Left Atrial Appendage Occlusion for Stroke Prevention
Abstract: Atrial fibrillation (AF) remains the most common arrhythmia encountered in clinical practice. One of its most devastating complication is the development of thromboembolism leading to stroke. The left atrial appendage (LAA) has been shown to be the site of thrombus formation in the majority of strokes associated with AF. Anticoagulation with warfarin has been the treatment of choice for prevention of embolic events in these patients, but it does have significant limitations including bleeding, need for continued follow-up blood tests, and drug–drug interactions. Although newer anticoagulants have been develope...
Source: Current Problems in Cardiology - September 24, 2012 Category: Cardiology Authors: Oluseun Alli, David R. Holmes Source Type: research
Computer tomography assessment of pedicle screw placement in thoracic spine: comparison between free hand and a generic 3D-based navigation techniques
Conclusion In conclusion, 3D navigation-assisted pedicle screw placement is superior to free hand technique in the thoracic spine. Content Type Journal ArticleCategory Original ArticlePages 1-6DOI 10.1007/s00586-012-2505-7Authors Yasser Allam, Spine Unit, El-Hadra University Hospital, Alexandria, EgyptJ. Silbermann, Department of Spine Surgery, Waldklinikum, Gera, GermanyF. Riese, Department of Radiology, University Heart Centre, Leipzig, GermanyR. Greiner-Perth, Department of Orthopaedic and Neurosurgery, Hochfranken, Hof, Germany Journal European Spine JournalOnline ISSN 1432-0932Print ISSN 0940-6719
Source: European Spine Journal - September 24, 2012 Category: Orthopaedics Tags: European Spine Journal Source Type: research
Ultrasound-guided trunk and core blocks in infants and children
Abstract Regional anesthetic techniques for perioperative analgesia in children are being increasingly utilized with the reported advantages of providing superior analgesia, decreasing opioid consumption, and reducing opioid-related adverse effects. The following article reviews the available literature regarding core and trunk blocks in infants and children; specifically, transversus abdominis plane, ilioinguinal/iliohypogastric nerve, rectus sheath, lumbar plexus, and paravertebral and intercostal nerve blockade. The common indications and potential complications and adverse effects for each block are pres...
Source: Journal of Anesthesia - September 24, 2012 Category: Anesthesiology Tags: Journal of Anesthesia Source Type: research
A new partial trisomy 12p with artery catheter vagus, congenital cataracts, external auditory canal, and no turbinate.
This study supports that phenotypic variability depends on the type and extent of the associated partial monosomy. PMID: 22959136 [PubMed - in process]
Source: Gene - September 24, 2012 Category: Genetics & Stem Cells Authors: Liu YH, Xie RG, Zhang XY, Wei SD, He Y, Xu WF, Lin YY, Xiong F Tags: Gene Source Type: research