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This page shows you the most recent publications within this specialty of the MedWorm directory.

The Pain Course: A randomised controlled trial of a clinician-guided Internet-delivered cognitive behaviour therapy program for managing chronic pain and emotional well-being
Summary: Examination of a clinician-guided Internet-delivered cognitive behaviour therapy program for chronic pain found significant improvements in disability, anxiety, depression, and average pain ratings.Abstract: The present study evaluated the efficacy of a clinician-guided Internet-delivered cognitive behaviour therapy (iCBT) program, the Pain Course, to reduce disability, anxiety, and depression associated with chronic pain. Sixty-three adults with chronic pain were randomised to either a Treatment Group or waitlist Control Group. Treatment consisted of 5 iCBT-based lessons, homework tasks, additional resources, wee...
Source: Pain - May 23, 2013 Category: Anesthesiology Authors: Blake F. Dear, Nick Titov, Kathryn Nicholson Perry, Luke Johnston, Bethany M. Wootton, Matthew D. Terides, Ron M. Rapee, Jennifer L. Hudson Tags: Research papers Source Type: research

Sickness absence due to musculoskeletal diagnoses and risk of diagnosis-specific disability pension: A nationwide Swedish prospective cohort study
In conclusion, this nationwide cohort study reveals strongly increased risks of all-cause and diagnosis-specific disability pension among those sickness absent due to musculoskeletal diagnoses. (Source: Pain)
Source: Pain - May 23, 2013 Category: Anesthesiology Authors: Catarina Jansson, Kristina Alexanderson Tags: Research papers Source Type: research

Disabling musculoskeletal pain in working populations: Is it the job, the person, or the culture?
Summary: Large international variation in the prevalence of disabling forearm and low back pain was only partially explained by established personal and socioeconomic risk factors.Abstract: To compare the prevalence of disabling low back pain (DLBP) and disabling wrist/hand pain (DWHP) among groups of workers carrying out similar physical activities in different cultural environments, and to explore explanations for observed differences, we conducted a cross-sectional survey in 18 countries. Standardised questionnaires were used to ascertain pain that interfered with everyday activities and exposure to possible risk factor...
Source: Pain - May 23, 2013 Category: Anesthesiology Authors: David Coggon, Georgia Ntani, Keith T. Palmer, Vanda E. Felli, Raul Harari, Lope H. Barrero, Sarah A. Felknor, David Gimeno, Anna Cattrell, Consol Serra, Matteo Bonzini, Eleni Solidaki, Eda Merisalu, Rima R. Habib, Farideh Sadeghian, M. Masood Kadir, Sudat Tags: Research papers Source Type: research

Editorial Board
(Source: Pain)
Source: Pain - May 23, 2013 Category: Anesthesiology Source Type: research

The following abstracts were presented at the Annual Meeting of the Scottish Airway Group in Glasgow, February 2011
(Source: Anaesthesia)
Source: Anaesthesia - May 23, 2013 Category: Anesthesiology Tags: Abstract Source Type: research

Efficacy and safety of spontaneous ventilation technique using dexmedetomidine for rigid bronchoscopic airway foreign body removal in children
ConclusionDexmedetomidine may provide appropriately deep anesthesia and ideal conditions for rigid bronchoscopic airway foreign body removal without respiratory depression or hemodynamic instability. (Source: Pediatric Anesthesia)
Source: Pediatric Anesthesia - May 23, 2013 Category: Anesthesiology Authors: Yirong Cai, Wenxian Li, Kaizheng Chen Tags: Original Article Source Type: research

How effectively do midwives manage the care of obese pregnant women? A cross-sectional survey of Australian midwives.
CONCLUSIONS: Registered midwives need continuing professional development in communication and counselling to more effectively manage the care of obese pregnant women. The universal use of a clinical guideline may have a positive impact by helping midwives to base early care decisions on clinical evidence. PMID: 23485364 [PubMed - in process] (Source: Women Birth)
Source: Women Birth - May 23, 2013 Category: Midwifery Authors: Biro MA, Cant R, Hall H, Bailey C, Sinni S, East C Tags: Women Birth Source Type: research

Utilizing integrated facility design to improve the quality of a pediatric ambulatory surgery center
ConclusionsThe use of IFD in the design of a pediatric ambulatory clinic and surgery resulted in significant cost savings and improved clinical efficiency. (Source: Pediatric Anesthesia)
Source: Pediatric Anesthesia - May 23, 2013 Category: Anesthesiology Authors: Nicole Pelly, Brian Zeallear, Mark Reed, Lynn Martin Tags: Original Article Source Type: research

Video observation of anesthesia practice: a useful and reliable tool for quality improvement initiatives
ConclusionsAlthough video recording has been used to evaluate adherence to resuscitation protocols in both trauma and in neonatal resuscitation, (Pediatric Emergency Care, 26, 2010, 803; Pediatrics, 117, 2006, 658; Pediatrics, 106, 2000, 654) we believe this is the first time that video has been used to record before and after behaviors for an anesthesia quality improvement initiative. (Source: Pediatric Anesthesia)
Source: Pediatric Anesthesia - May 23, 2013 Category: Anesthesiology Authors: Sally E. Rampersad, Lizabeth D. Martin, Jeremy M. Geiduschek, Gillian K. Weiss, Shelly W. Bates, Lynn D. Martin Tags: Original Article Source Type: research

Alan Conn; his role in the development of the Anesthesia Department at Toronto SickKids
(Source: Pediatric Anesthesia)
Source: Pediatric Anesthesia - May 23, 2013 Category: Anesthesiology Authors: Robert E. Creighton, Ian A. Jeremy Sloan, David J. Steward Tags: Vignette Source Type: research

Using quality improvement methods to optimize resources and maximize productivity in an anesthesia screening and consultation clinic
ConclusionsBy applying quality improvement methods, we identified key drivers for the institution of an NP‐assisted preoperative screening process and successfully implemented this process while redirecting anesthesiologists' time for the provision of non‐OR anesthesia. This project was instrumental in improving the matching of provider skills with clinical need while maintaining superior outcomes at the lowest possible cost. (Source: Pediatric Anesthesia)
Source: Pediatric Anesthesia - May 23, 2013 Category: Anesthesiology Authors: Anna M. Varughese, Nancy Hagerman, Mari E. Townsend Tags: Original Article Source Type: research

The protective effect of dexmedetomidine on bupivacaine-induced sciatic nerve inflammation is mediated by mast cells.
CONCLUSION: Dexmedetomidine may ameliorate bupivacaine-induced neurotoxicity by modulating mast cell degranulation. The neuroprotective effect of dexmedetomidine may make it a suitable adjuvant agent to local anesthetics in peripheral nerve blocks. PMID: 23544611 [PubMed - in process] (Source: Clinical and Investigative Medicine)
Source: Clinical and Investigative Medicine - May 22, 2013 Category: Biomedical Science Authors: Tüfek A, Kaya S, Tokgöz O, Firat U, Evliyaoğlu O, Çelik F, Karaman H Tags: Clin Invest Med Source Type: research

Requirement for nuclear calcium signaling in Drosophila long-term memory.
Abstract Calcium is used throughout evolution as an intracellular signal transducer. In the mammalian central nervous system, calcium mediates the dialogue between the synapse and the nucleus that is required for transcription-dependent persistent neuronal adaptations. A role for nuclear calcium signaling in similar processes in the invertebrate brain has yet to be investigated. Here, we show by in vivo calcium imaging of adult brain neurons of the fruit fly Drosophila melanogaster, that electrical foot shocks used in olfactory avoidance conditioning evoked transient increases in cytosolic and nuclear calcium conce...
Source: Science Signaling - May 22, 2013 Category: Biomedical Science Authors: Weislogel JM, Bengtson CP, Müller MK, Hörtzsch JN, Bujard M, Schuster CM, Bading H Tags: Sci Signal Source Type: research

Complications of Perioperative Non-OB Epidural PuncturesComplications of Perioperative Non-OB Epidural Punctures
What are the patient risk factors and incidence of immediate complications following epidural puncture? BMC Anesthesiology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 22, 2013 Category: Consumer Health News Tags: Anesthesiology Journal Article Source Type: news

Efficacy and Safety of Low Dose Subcutaneous Diclofenac in the Management of Acute Pain: A Randomized Double‐Blind Trial
ConclusionSingle SC doses of diclofenac HPβCD of 25 and 50 mg are effective and well tolerated for relieving pain compared with placebo. (Source: Pain Practice)
Source: Pain Practice - May 22, 2013 Category: Anesthesiology Authors: Thomas Dietrich, Rachel Leeson, Barbara Gugliotta, Birte Petersen Tags: Original Article Source Type: research

Self‐Critical Perfectionism Predicts Outcome in Multidisciplinary Treatment for Chronic Pain
ConclusionResults suggest that self‐critical perfectionistic personality features may negatively interfere with treatment response in patients with chronic pain. Thus, findings indicate that chronic pain patients with high levels of self‐critical perfectionism may benefit less from brief interventions such as MPEP, and therefore may need more intensive and tailored treatment. (Source: Pain Practice)
Source: Pain Practice - May 22, 2013 Category: Anesthesiology Authors: Stefan Kempke, Patrick Luyten, Peter Wambeke, Eline Coppens, Bart Morlion Tags: Original Article Source Type: research

Severe Left Main Coronary Artery Stenosis with Abnormal Branching Pattern in a Patient with Mild Supravalvar Aortic Stenosis and Williams‐Beuren Syndrome
Abstract Williams–Beuren syndrome (WBS) is a multisystem genetic disorder comprising of craniofacial, developmental, and cardiac malformations. The most common cardiac defects found are supravalvar aortic stenosis and peripheral pulmonary stenosis. However, WBS should be regarded as a general arteriopathy consisting of stenoses of medium‐ and large‐sized arteries including the coronary arteries. Cardiac manifestations are often the initial reason for referral and careful cardiovascular assessment is important as coronary artery involvement confers a significant anesthetic risk and may be associated with ischemia and ...
Source: Congenital Heart Disease - May 22, 2013 Category: Cardiology Authors: Guido E. Pieles, Victor Ofoe, Gareth J. Morgan Tags: Case Report Source Type: research

Attributes Associated with Patient Perceived Outcome in an Academic Chronic Pain Clinic
ConclusionsOur results suggest that pain physicians may positively impact patient perceived outcomes of clinic visits by explaining the patient's condition and treatment, providing instructions, and taking the time to understand the patient and their values. (Source: Pain Practice)
Source: Pain Practice - May 22, 2013 Category: Anesthesiology Authors: Terrence L. Trentman, Yu‐Hui H. Chang, James J. Chien, David M. Rosenfeld, Andrew W. Gorlin, David P. Seamans, John A. Freeman, Laurie L. Wilshusen Tags: Original Article Source Type: research

Efficacy and Safety of Carisbamate in Patients with Diabetic Neuropathy or Postherpetic Neuralgia: Results from 3 Randomized, Double‐Blind Placebo‐Controlled Trials
Abstract The results of 3 proof‐of‐concept studies to evaluate carisbamate's efficacy and safety in treating neuropathic pain are presented. In studies 1 (postherpetic neuralgia, n = 91) and 2 (diabetic neuropathy, n = 137), patients received carisbamate 400 mg/day or placebo for 4 weeks and then crossed over to the other treatment for 4 weeks. In study 3 (diabetic neuropathy, higher carisbamate doses), patients (n = 386) were randomized (1:1:1:1) to receive either carisbamate 800 mg/day, 1200 mg/day, pregabalin 300 mg/day or placebo for 15 weeks. Primary efficacy end point was the mean of the last 7 avera...
Source: Pain Practice - May 22, 2013 Category: Anesthesiology Authors: Timothy Smith, Allitia DiBernardo, Yingqi Shi, Mike J. Todd, H. Robert Brashear, Lisa M. Ford Tags: Original Article Source Type: research

Linguistic Analysis of Face‐to‐Face Interviews with Patients with An Explicit Request for Euthanasia, their Closest Relatives, and their Attending Physicians: the Use of Modal Verbs in Dutch
ConclusionsLinguistic analysis can help medical professionals to better understand their communicative skills, styles, and approach to patients in end‐of‐life situations. We have shown how linguistic analysis can contribute to a better understanding of physician–patient interaction. Moreover, we have illustrated the usefulness of interdisciplinary research in the medical domain. (Source: Pain Practice)
Source: Pain Practice - May 22, 2013 Category: Anesthesiology Authors: Sylvain M. Dieltjens, Priscilla C. Heynderickx, Marianne K. Dees, Kris C. Vissers Tags: Original Article Source Type: research

Report of a Preliminary Discontinued Double‐Blind, Randomized, Placebo‐Controlled Trial of the Anti‐TNF‐α Chimeric Monoclonal Antibody Infliximab in Complex Regional Pain Syndrome
ConclusionsThis study was terminated before the required number of participants had been reached for sufficient statistical power. Nevertheless, a trend was found toward an effect of infliximab on the initially high TNF‐α concentration. (Source: Pain Practice)
Source: Pain Practice - May 22, 2013 Category: Anesthesiology Authors: Maaike Dirckx, George Groeneweg, Feikje Wesseldijk, Dirk L. Stronks, Frank J.P.M. Huygen Tags: Original Article Source Type: research

Concern for Pain in the Pre‐Operative Period‐ Is the Internet Being Used for Information By Patients?
This study was conducted to provide information regarding prevalence of pain, type of provider managing pain, and use of Internet for information regarding pain, among patients coming for presurgical anesthesia consultation at a major academic institution. MethodsWith IRB approval, patients were invited to participate in a voluntary and anonymous 14 question survey given to them when they presented for anesthesia consultation prior to their surgical procedure. The qualitative/categorical data were summarized by number (percentage [%]) and analyzed by Chi‐square test or Fisher's exact test as appropriate. All data analyse...
Source: Pain Practice - May 22, 2013 Category: Anesthesiology Authors: Viji Kurup, Susan Dabu‐Bondoc, Audrey Senior, Feng Dai, Denise Hersey, Nalini Vadivelu Tags: Original Article Source Type: research

Cognitive Function in Older Patients with Postherpetic Neuralgia
ConclusionThis study shows the deleterious effect of systemic PHN treatment on several domains of cognition. Cognitive impairment associated with pain and antidepressants may be reversed by topical pain management. Topical treatment with 5% lidocaine medicated plaster is a valuable alternative for pain alleviation and maintains cognitive integrity in this vulnerable population. (Source: Pain Practice)
Source: Pain Practice - May 22, 2013 Category: Anesthesiology Authors: Gisèle Pickering, Bruno Pereira, Florentin Clère, Marc Sorel, Geraldine Montgazon, Malou Navez, Pascale Picard, Delphine Roux, Véronique Morel, Rachida Salimani, Mireille Adda, Valérie Legout, Claude Dubray Tags: Original Article Source Type: research

Hitachi and PENTAX Collaborate on HI VISION Preirus Ultrasound
Hitachi has released its HI VISION Preirus ultrasound system that it developed in conjunction with PENTAX. The system can be used in most ultrasound imaging situations, including OB/GYN, in interventional procedures, and for transesophageal cardiac echos thanks to an optional add on.From a PENTAX news release:Read More (Source: Medgadget Anesthesiology)
Source: Medgadget Anesthesiology - May 21, 2013 Category: Anesthesiology Authors: Editors Tags: Anesthesiology Cardiology Critical Care Emergency Medicine Ob/Gyn Radiology Urology Vascular Surgery Source Type: news

Nihon Kohden’s New Lightweight Mobile Transport Monitor
Japan’s Nihon Kohden is releasing in the U.S. its new patient transport monitor. The device weighs 3.5 pounds (1.5 Kg), features a touch screen 5.5 inch (14 cm) screen, and keeps track of a 12-lead ECG, respiration, pulse oximetry, patient temperature, blood pressure, and a few other things. The device records unusual events for later analysis, as well as trends that clinicians can use to get a better perspective on a patient’s condition.The system includes a removable battery that will keep the monitor running for five hours and a memory card stores all the readings for easy data transfer once the patient arri...
Source: Medgadget Anesthesiology - May 21, 2013 Category: Anesthesiology Authors: Editors Tags: Anesthesiology Cardiology Critical Care Emergency Medicine Military Medicine Source Type: news

Potential of biodegradable microneedles as a transdermal delivery vehicle for lidocaine.
Abstract There has been an increasing interest in applying biotechnology in formulating and characterising new and innovative drug delivery methods, e.g., drug-loaded biodegradable microneedles within the area of transdermal delivery technology. Recently, microneedles have been proposed for use in pain management, e.g., post-operative pain management through delivery of a local anaesthetic, namely, lidocaine. Lidocaine is a fairly common, marketed prescription-based, local anaesthetic pharmaceutical, applied for relieving localised pain and lidocaine-loaded microneedles have been explored. The purpose of this revie...
Source: Biotechnology Letters - May 21, 2013 Category: Biotechnology Authors: Nayak A, Das DB Tags: Biotechnol Lett Source Type: research

A Critical Appraisal of the Evidence for Botulinum Toxin Type A in the Treatment for Cervico‐Thoracic Myofascial Pain Syndrome
Abstract Myofascial pain syndrome (MPS) is a musculoskeletal condition characterized by regional pain and muscle tenderness associated with the presence of myofascial trigger points (MTrPs). The last decade has seen an exponential increase in the use of botulinum toxin (BTX) to treat MPS. To understand the medical evidence substantiating the role of therapeutic BTX injections and to provide useful information for the medical practitioner, we applied the principles of evidence‐based medicine to the treatment for cervico‐thoracic MPS. A search was conducted through MEDLINE (PubMed, OVID, MDConsult), EMBASE, SCOPUS and th...
Source: Pain Practice - May 21, 2013 Category: Anesthesiology Authors: Mehul J. Desai, Tatyana Shkolnikova, Andrew Nava, Danielle Inwald Tags: Review Article Source Type: research

Ultrasound‐Guided Paravertebral Neurolytic Block: A Report of Two Cases
We report two cases of ultrasound‐guided neurolytic paravertebral blocks in patients suffering from intense cancer‐related thoracic pain. Ultrasound was used to identify the space and plane of injection at the mid‐thoracic level. Absolute alcohol was used to block the nerves at different segments. The two patients had great pain relief. Neurolytic paravertebral block can be a useful technique in patients with intractable cancer pain. Because of the risk of complication, it is recommended that this technique should be limited to relief of intractable pain in cancer patients with a poor prognosis. (Source: Pain Practice)
Source: Pain Practice - May 21, 2013 Category: Anesthesiology Authors: Tariq Malik Tags: Clinical Report Source Type: research

Fish Oil and Post-Operative Atrial Fibrillation A Meta-Analysis of Randomized Controlled Trials
Post-operative atrial fibrillation (PoAF) is among the most common complications of cardiac surgery and substantially increases morbidity and healthcare costs. Despite decades of surgical, anesthetic, and medical advances, rates of PoAF remain largely unchanged. Experiments and animal models suggest that perioperative fish oil (omega-3 fatty acids) may reduce PoAF (1). We recently reported in a large, multinational randomized trial that perioperative fish oil did not reduce PoAF (2). Yet several other trials have evaluated this question, with mixed results. Most of these trials were small, and some were open label (i.e., n...
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - May 20, 2013 Category: Cardiology Source Type: research

Reply
We want to thank Drs Farid and Morris-Stiff for their interest in our manuscript. They have indeed pointed out some of the limitations of the study. While a randomized controlled trial or at least a case-matched series between open pancreaticoduodenectomy (OPD) and laparoscopic pancreaticoduodenectomy (LPD) may have been ideal, we performed our analysis as described for 2 reasons. The first reason was to increase the number of OPDs with which to compare our LPD group. The increased denominator of the comparison group allowed us to gain significance with our results. Additionally, the surgeons performing OPD before we did ...
Source: Journal of the American College of Surgeons - May 20, 2013 Category: Surgery Authors: Horacio J. Asbun, John A. Stauffer Tags: Letters Source Type: research

Ketamine Works in OCD, Stubborn Depression (CME/CE)
SAN FRANCISCO (MedPage Today) -- The anesthetic agent ketamine continues to show tantalizing promise in psychiatric disorders, with results from new studies in intractable depression and obsessive-compulsive disorder. (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - May 20, 2013 Category: Psychiatry Source Type: news

No Link Between Anesthesia and DementiaNo Link Between Anesthesia and Dementia
However, this new study does not settle the controversy surrounding postoperative cognitive decline. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 20, 2013 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news

Blood Loss During Endoscopic Sinus SurgeryBlood Loss During Endoscopic Sinus Surgery
Blood loss during endoscopic sinus surgery was similar for total intravenous anesthesia (TIVA) with propofol and for inhalational anesthesia with sevoflurane, in a randomized trial. Reuters Health Information (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 20, 2013 Category: Consumer Health News Tags: General Surgery News Source Type: news

Ketamine Associated With Rapid Antidepressant Effect In Largest Clinical Trial To Date
Patients with treatment-resistant major depression saw dramatic improvement in their illness after treatment with ketamine, an anesthetic, according to the largest ketamine clinical trial to-date led by researchers from the Icahn School of Medicine at Mount Sinai. The antidepressant benefits of ketamine were seen within 24 hours, whereas traditional antidepressants can take days or weeks to demonstrate a reduction in depression... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 20, 2013 Category: Consumer Health News Tags: Depression Source Type: news

Treatment with the sphingosine‐1‐phosphate analogue FTY 720 reduces loss of plasma volume during experimental sepsis in the rat
ConclusionFTY720 in a dose without haemodynamic side effects reduces loss of plasma volume during experimental sepsis most likely because of reduction in permeability and may therefore be beneficial in sepsis. (Source: Acta Anaesthesiologica Scandinavica)
Source: Acta Anaesthesiologica Scandinavica - May 20, 2013 Category: Anesthesiology Authors: CORNELIA LUNDBLAD, HELEN AXELBERG, PER‐OLOF GRÄNDE Tags: Original Article Source Type: research

A Preliminary Study to Determine if a Muscle Pain Protocol Can Produce Long‐Term Relief in Chronic Back Pain Patients
ConclusionIn patients thought to have neuraxial pain, identification and treatment of painful muscles had statistically significant long‐lasting and clinically meaningful reductions in pain and improvement in function. Muscle and tendon attachments may be an important and treatable source of pain in patients diagnosed with pre and postsurgical neuraxial pain. (Source: Pain Medicine)
Source: Pain Medicine - May 20, 2013 Category: Anesthesiology Authors: Norman J. Marcus, Allyson Augusta Shrikhande, Bill McCarberg, Edward Gracely Tags: Original Article Source Type: research

Excessive Peptidergic Sensory Innervation of Cutaneous Arteriole–Venule Shunts (AVS) in the Palmar Glabrous Skin of Fibromyalgia Patients: Implications for Widespread Deep Tissue Pain and Fatigue
ConclusionsThe excessive sensory innervation to the glabrous skin AVS is a likely source of severe pain and tenderness in the hands of FM patients. Importantly, glabrous AVS regulate blood flow to the skin in humans for thermoregulation and to other tissues such as skeletal muscle during periods of increased metabolic demand. Therefore, blood flow dysregulation as a result of excessive innervation to AVS would likely contribute to the widespread deep pain and fatigue of FM. SNRI compounds may provide partial therapeutic benefit by enhancing the impact of sympathetically mediated inhibitory modulation of the excess sensory ...
Source: Pain Medicine - May 20, 2013 Category: Anesthesiology Authors: Phillip J. Albrecht, Quanzhi Hou, Charles E. Argoff, James R. Storey, James P. Wymer, Frank L. Rice Tags: Research Article Source Type: research

Answer to Dr Alexey Schamko
(Source: Acta Anaesthesiologica Scandinavica)
Source: Acta Anaesthesiologica Scandinavica - May 20, 2013 Category: Anesthesiology Authors: H. FLAATTEN, M. HANEY, J. WERNERMAN Tags: Letter to the Editor Source Type: research