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Zogenix Initiates Pivotal Phase 3 Clinical Trial For Novel Formulation Of Oral Controlled-Release Hydrocodoneemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Zogenix, Inc. ("Zogenix"), a privately held pharmaceutical company, announced that it has initiated a pivotal Phase 3 clinical trial with ZX002, a novel, oral, controlled-release formulation of hydrocodone without acetaminophen. ZX002 is being developed for the treatment of moderate to severe pain in individuals who require around-the-clock opioid therapy for the control of pain... (Source: Pain / Anesthetics News From Medical News Today)
Source: Pain / Anesthetics News From Medical News Today - March 18, 2010 Category: Anesthesiology Tags: Pain / Anesthetics Source Type: news

Acetaminophen Alone Works Well For Postpartum Painemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
For many mothers of newborns, lingering pain from the delivery can interfere with their first days with their infant. A recent review examined whether over-the-counter medications containing acetaminophen Tylenol for example provided adequate relief for such pain and concluded that they are effective... (Source: Pain / Anesthetics News From Medical News Today)
Source: Pain / Anesthetics News From Medical News Today - March 17, 2010 Category: Anesthesiology Tags: Pain / Anesthetics Source Type: news

Pelvic Pain And Surgeries In Women Before Interstitial Cystitis/Painful Bladder Syndrome - Chronic Pelvic Pain, BPS And Pelvic Surgical Proceduresemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
UroToday.com - For years, bladder pain syndrome series have reported apparently high numbers of BPS patients with a history of hysterectomy and other pelvic surgeries. No study has compared cases with controls prior to onset of BPS symptoms... (Source: Pain / Anesthetics News From Medical News Today)
Source: Pain / Anesthetics News From Medical News Today - March 17, 2010 Category: Anesthesiology Tags: Urology / Nephrology Source Type: news

Essentials of cardiac anesthesiaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
‘Essentials of Cardiac Anesthesia’ is the first edition of this title which has been added to the ‘Essentials in Anaesthesia and Critical Care’ series by the Saunders Elsevier publishing house. The book is a new publication written by a distinguished list of North American experts, and edited by Joel A Kaplan, well known for his established textbook ‘Cardiac Anesthesia’, now in its 5th edition. (Source: Current Anaesthesia and Critical Care)
Source: Current Anaesthesia and Critical Care - March 16, 2010 Category: Anesthesiology Authors: B.M. Thomas Tags: Book Reviews Source Type: journals

Anaesthesiaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The intended reader of this book is the new anaesthetic trainee who, with little or no previous anaesthetic experience, expects a basic yet comprehensive insight into the principles of anaesthetic practice and a practical guide to clinical anaesthetic skills. (Source: Current Anaesthesia and Critical Care)
Source: Current Anaesthesia and Critical Care - March 16, 2010 Category: Anesthesiology Authors: Susan Farrow Tags: Book Reviews Source Type: journals

Reply to “Eclampsia a rare complication: A reminder that magnesium sulphate saves lives”email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We read with great interest the commentary of Durbgidge J, “Eclampsia a rare complication: A reminder that magnesium sulphate saves lives” on our case report “Posterior Reversible Encephalopathy Syndrome (PRES) in a patient of eclampsia with ‘partial’ HELLP-syndrome presenting with status-epilepticus”. We agree with you fully that there is a continuing gap between the availability of healthcare and access to drugs between the developed and developing countries. You have rightly pointed out the important role of magnesium sulphate in the management of preeclampsia and eclampsia and it is an indispensable drug in...
Source: Current Anaesthesia and Critical Care - March 16, 2010 Category: Anesthesiology Authors: Harihar V. Hegde, P. Raghavendra Rao Tags: Letter to the Editor Source Type: journals

Tumour necrosis factor inhibitors in critical care: Case report with review of the literatureemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Summary: This is a case report of a patient with Crohn's disease admitted to hospital with a typical flare. The main symptoms were abdominal pain and haemorrhagic diarrhoea. During the current admission she was commenced on her first course of Infliximab.The clinical benefits of monoclonal TNF-alpha inhibitors are described. The anxieties relating to infectious complications that may be, in part related to the TNF-alpha inhibition are also discussed. At present the impact of these agents on critical illness is unclear but as the use of these effective drugs increase it is inevitable there will be an increase in patients pr...
Source: Current Anaesthesia and Critical Care - March 16, 2010 Category: Anesthesiology Authors: Gustav F. Strandvik, Sara Polhill Tags: Case Reports Source Type: journals

A near miss; malpositioned nasogastric tube in the left bronchus of a spontaneously breathing critically-ill patientemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We report a 60-year male in whom the attempted NGT insertion led to a near fatal complication. He was admitted to the medical intensive care-unit of our institute with dysphagia, cough with expectoration and breathlessness. In an un-cooperative patient with ineffective cough, the administration of sedation and multiple attempts to place the NGT resulted in an impacted tooth in the upper esophagus, and misplacement of the NGT. An urgent chest radiograph showed that the NGT had entered into the airway and its tip lay in the left main bronchus. A brief review of the complications associated with NGT insertion is presented. (S...
Source: Current Anaesthesia and Critical Care - March 16, 2010 Category: Anesthesiology Authors: Harihar V. Hegde, P. Raghavendra Rao Tags: Case Reports Source Type: journals

“To MAP or not to MAP; is that the question?” The role of platelet function tests in the perioperative management of patients on antiplatelet therapyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Summary: Platelets aggregate at the site of ruptured atherosclerotic plaques and have a key role in the pathophysiology of occlusive vascular events. Antiplatelet agents (APA) have proven efficacy in the primary and secondary prevention of ischaemic heart and cerebrovascular disease. The peri-operative management of patients taking such drugs is increasingly challenging and necessitates consideration of the risk of thrombosis following cessation of APA versus that of haemorrhage through continuation. We discuss the current and future role of platelet function tests in optimising clinical management of patients taking APA a...
Source: Current Anaesthesia and Critical Care - March 16, 2010 Category: Anesthesiology Authors: N. Jones, R.H. Broomhead, J. Kaur, S.V. Mallett Tags: Points of View Source Type: journals

Commentary on transfusion triggersemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In this review article Bunker et al. present their approach to the clinical conundrum regarding the use of red cell transfusion triggers. The impetus to use numerical values of haemoglobin concentration as transfusion triggers has been driven by several factors that have been clearly outlined by the authors. Whilst public perception may differ, blood itself has never been safer and currently the most pressing problem associated with this pharmacological product is the reduction in the donor pool and the exponential rise in cost due to even more sensitive screening tools and pathogen inactivation methods. This has to be te...
Source: Current Anaesthesia and Critical Care - March 16, 2010 Category: Anesthesiology Authors: Munita Grover Tags: Points of View Source Type: journals

Transfusion triggersemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Summary: Transfusion triggers are increasingly accepted in surgery and in the critically ill. There is very little evidence to suggest a restrictive policy is harmful although higher levels might be sensible in those with cardiovascular disease. A considerable tranche of literature shows that blood is bad for a patient but to date no clear mechanism has emerged and there is an argument that needing blood, a surrogate for illness may be as relevant. The impact of anaemia in the postoperative phase has not been evaluated adequately. The triggers lend themselves to non-acute elective situations but where there is acute blood ...
Source: Current Anaesthesia and Critical Care - March 16, 2010 Category: Anesthesiology Authors: Neil Soni, Nick Bunker Tags: Points of View Source Type: journals

Continuing professional development: Renal MCQs and self-assessmentemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
True. Pre-existing chronic kidney disease is a risk factor for acute kidney injury (Source: Current Anaesthesia and Critical Care)
Source: Current Anaesthesia and Critical Care - March 16, 2010 Category: Anesthesiology Tags: Continuing Professional Development Source Type: journals

Continuing professional development: Renal MCQs and self-assessment questionsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
1. Risk factors for acute kidney injury include Pre-existing chronic kidney disease (Source: Current Anaesthesia and Critical Care)
Source: Current Anaesthesia and Critical Care - March 16, 2010 Category: Anesthesiology Authors: Andrew Lewington Tags: Continuing Professional Development Source Type: journals

Management of the peri-operative and critically ill renal transplant patientemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Summary: Recipients of successful renal transplants experience a markedly improved quality of life and almost certainly improved survival compared to patients treated with dialysis. Haemodialysis treatment in the immediate period prior to transplantation is associated with a poorer outcome including a higher rate of delayed graft function (DGF). Individuals undergoing renal transplantation require close intra-operative monitoring with optimisation of intravascular fluid volume to maximise renal transplant perfusion. Whether mannitol, loop diuretics, dopamine or other therapies influence the rate of DGF is not possible to d...
Source: Current Anaesthesia and Critical Care - March 16, 2010 Category: Anesthesiology Authors: Chas Newstead Tags: Focus on: Renal Source Type: journals

Renal replacement therapy in the intensive care unitemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This article explores the techniques available for renal replacement and support in the intensive care unit, discussing vascular access, choice of technique, choice of membrane, choice of dialysis buffer and strategies for maintaining circuit patency. It examines the techniques in common use in the United Kingdom and the outcome following renal replacement therapy, discussing some of the controversies surrounding renal replacement in terms of timing and dose. It also discusses some future development in technologies for renal replacement. (Source: Current Anaesthesia and Critical Care)
Source: Current Anaesthesia and Critical Care - March 16, 2010 Category: Anesthesiology Authors: A.D. Drummond, M.C. Bellamy Tags: Focus on: Renal Source Type: journals

Prevention of acute kidney injury in the intensive care unitemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Summary: Acute Kidney injury (AKI) is a relatively common condition in the intensive care unit and is associated with an increase in mortality. Whilst it can be treated by the use of renal replacement therapies an independent increase in mortality still exists. It is therefore seems intuitive that the prevention of AKI should be associated with a reduction in both mortality and morbidity and an improvement in patient care for this reason there has been many attempts to develop strategies to reduce the incidence of AKI. These strategies involve the use of therapeutic agents to prevent renal failure, the avoidance of nephrot...
Source: Current Anaesthesia and Critical Care - March 16, 2010 Category: Anesthesiology Authors: Stuart Murdoch Tags: Focus on: Renal Source Type: journals

Acute kidney injury in the critically ill patientemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract: The stage at which acute kidney injury (AKI) is detected is dependent upon the definition used. More recently it has been demonstrated that even relatively small increments of serum creatinine portend a worse outcome. This has prompted the development of new definitions based on small rises in serum creatinine or decreases in urine output. Acute kidney injury on the intensive care unit (ICU) is usually multifactorial secondary to hypovolaemia and sepsis resulting in hypoperfusion of the kidneys. In patients with good baseline kidney function the condition is generally reversible if the patient regains health. How...
Source: Current Anaesthesia and Critical Care - March 16, 2010 Category: Anesthesiology Authors: Seerapani Gopaluni, Simon Lines, Andrew J.P. Lewington Tags: Focus on: Renal Source Type: journals

Critical care nephrologyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Over the last few years there has been an increased interest in acute renal failure now termed acute kidney injury (AKI) particularly in relation to its association with increased patient morbidity, mortality and length of hospital stay. The term AKI encompasses all types of acute renal failure (ARF). The National Service Framework (NSF) for Renal Services has recommended that patients at risk of suffering from AKI should be identified promptly, with hospital services delivering high-quality, clinically appropriate care in partnership with specialised teams. (Source: Current Anaesthesia and Critical Care)
Source: Current Anaesthesia and Critical Care - March 16, 2010 Category: Anesthesiology Authors: Andrew Lewington Tags: Focus on: Renal Source Type: journals

Editorial Board & Aims and Scopeemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Current Anaesthesia and Critical Care)
Source: Current Anaesthesia and Critical Care - March 16, 2010 Category: Anesthesiology Source Type: journals

Discovery Of Codeine And Morphine Genes By University Of Calgary Researchersemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Researchers at the University of Calgary have discovered the unique genes that allow the opium poppy to make codeine and morphine, thus opening doors to alternate methods of producing these effective painkillers either by manufacturing them in a lab or controlling the production of these compounds in the plant... (Source: Pain / Anesthetics News From Medical News Today)
Source: Pain / Anesthetics News From Medical News Today - March 16, 2010 Category: Anesthesiology Tags: Pain / Anesthetics Source Type: news

Vertebroplasty For Patients With Osteoporosis Provides Effective Pain Reliefemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Patient selection is key for vertebroplasty a minimally invasive treatment performed by interventional radiologists in individuals with painful osteoporotic vertebral compression fractures that fail to respond to conventional medical therapy to be effective and successful, according to a study of more than 1,500 persons who were followed over seven years... (Source: Pain / Anesthetics News From Medical News Today)
Source: Pain / Anesthetics News From Medical News Today - March 16, 2010 Category: Anesthesiology Tags: Bones / Orthopedics Source Type: news

Forensic Laboratories Develops First Oral Fluid Test For Tapentadolemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Forensic Laboratories, a Denver-based laboratory specializing in toxicology services for drug abuse, has unveiled the first oral fluid test for Tapentadol, a new federally approved drug prescribed by doctors for pain management. Previously, laboratories could only detect the drug through urine using liquid chromatography-mass spectrometry-mass spectrometry (LC/MS/MS) technology... (Source: Pain / Anesthetics News From Medical News Today)
Source: Pain / Anesthetics News From Medical News Today - March 16, 2010 Category: Anesthesiology Tags: Pain / Anesthetics Source Type: news

Hip Fracture Risks Linger After Recoveryemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Title: Hip Fracture Risks Linger After RecoveryCategory: Health NewsCreated: 3/16/2010 10:57:00 AMLast Editorial Review: 3/16/2010 10:57:38 AM (Source: MedicineNet Chronic Pain General)
Source: MedicineNet Chronic Pain General - March 16, 2010 Category: Anesthesiology Source Type: consumer

Meditation Techniques Effective For Pain Reliefemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Meditation has analgesic benefits associated with creating a relaxed state of mind and enhancing the ability to moderate reactions to pain, according to new research published in The Journal of Pain, the peer review publication of the American Pain Society... (Source: Pain / Anesthetics News From Medical News Today)
Source: Pain / Anesthetics News From Medical News Today - March 16, 2010 Category: Anesthesiology Tags: Pain / Anesthetics Source Type: news

Reducing delirium in elderly patients with hip fracture: a multi-factorial intervention studyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
There is an evident need for improved management of elderly patients with trauma in order to avoid common and troublesome complications such as delirium. The aim of this study was to investigate whether an implementation of a multi-factorial program including intensified pre-hospital and perioperative treatment and care could reduce the incidence of delirium in elderly patients with hip fracture, cognitively intact at admission to the hospital. In addition, we explored the factors that characterize patients who developed delirium. A prospective, quasi-experimental design was used. A total of 263 patients with hip fracture ...
Source: Acta Anaesthesiologica Scandinavica - March 16, 2010 Category: Anesthesiology Authors: K. B. BJÖRKELUND, A. HOMMEL, K.-G. THORNGREN, L. GUSTAFSON, S. LARSSON, D. LUNDBERG Source Type: journals

Disclosure of industry relationships by anesthesiologists: is the conflict of interest resolved?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Purpose of review: Anesthesiologists are flooded with requests that they themselves reveal their associations with industry and other external sources of financial support and also with stories about adverse outcomes related to poorly managed conflict of interest (COI) in research, education, and clinical practice. Guidelines for evaluating COI in these areas are needed and provision of such guidelines is the goal of this review. Recent findings: The medical literature and lay press provide ample publications outlining the extent of the COI problem and recent efforts to manage COI with numerous opinions on how to best acc...
Source: Current Opinion in Anaesthesiology - March 15, 2010 Category: Anesthesiology Tags: Ethics, economics and outcome: Edited by Alex Macario Source Type: journals

Challenges that limit meaningful use of health information technologyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Purpose: Health information technology (HIT) is perceived as an essential component for addressing inefficiencies in healthcare. Without understanding the challenges that limit meaningful use of HIT, there is a high chance that institutions will convert complex paper-based systems to expensive digital chaos. Recent findings: Clinical information systems do not communicate with each other automatically because integration of existing data standards is lacking. Data standards for medical specialties need further development. Database architectures are often designed to support single clinical applications and are not easily...
Source: Current Opinion in Anaesthesiology - March 15, 2010 Category: Anesthesiology Tags: Ethics, economics and outcome: Edited by Alex Macario Source Type: journals

Progenics To Advance Oral Methylnaltrexone Into Late Stage Clinical Developmentemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Progenics Pharmaceuticals, Inc. (Nasdaq: PGNX) today announced that it plans to advance oral methylnaltrexone for the treatment of opioid-induced constipation (OIC) into late stage clinical development and will commence a phase 2b/3 clinical trial of a methylnaltrexone tablet in chronic-pain patients in the second half of 2010... (Source: Pain / Anesthetics News From Medical News Today)
Source: Pain / Anesthetics News From Medical News Today - March 15, 2010 Category: Anesthesiology Tags: Pain / Anesthetics Source Type: news

Getting Athletes 'Back In The Game' Faster: Minimally Invasive Sports Hernia Repairemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
A new minimally invasive sports hernia repair gets athletes back in the game 3 times faster than the traditional repair, according to a new study presented at the American Orthopaedic Society for Sports Medicine's Specialty Day in New Orleans, (March 13). Sports hernia were often difficult to diagnose and prior to this new repair had a lengthy rehabilitation time... (Source: Pain / Anesthetics News From Medical News Today)
Source: Pain / Anesthetics News From Medical News Today - March 15, 2010 Category: Anesthesiology Tags: Sports Medicine / Fitness Source Type: news

Knee Surgeon's Expectations May Differ From Yoursemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Title: Knee Surgeon's Expectations May Differ From YoursCategory: Health NewsCreated: 3/12/2010 2:10:00 PMLast Editorial Review: 3/15/2010 (Source: MedicineNet Chronic Pain General)
Source: MedicineNet Chronic Pain General - March 15, 2010 Category: Anesthesiology Source Type: consumer

Bad Behavior in Youth Linked to Chronic Pain Later in Lifeemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Title: Bad Behavior in Youth Linked to Chronic Pain Later in LifeCategory: Health NewsCreated: 3/12/2010 2:10:00 PMLast Editorial Review: 3/15/2010 (Source: MedicineNet Chronic Pain General)
Source: MedicineNet Chronic Pain General - March 15, 2010 Category: Anesthesiology Source Type: consumer

High-Impact Sports Might Not Harm Knee Replacementsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Title: High-Impact Sports Might Not Harm Knee ReplacementsCategory: Health NewsCreated: 3/12/2010 10:10:00 AMLast Editorial Review: 3/15/2010 (Source: MedicineNet Chronic Pain General)
Source: MedicineNet Chronic Pain General - March 15, 2010 Category: Anesthesiology Source Type: consumer

Ondansetron is as effective as diphenhydramine for treatment of morphine-induced pruritus after cesarean deliveryemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Subarachnoid (SA) morphine, highly effective for the management of pain after a cesarean delivery, is associated with a significant incidence of pruritus in up to 80% of patients. No previous study has compared the effectiveness of ondansetron (5-HT3 antagonist) vs. diphenhydramine (H1 receptor blocker) for the treatment of this side effect. In this randomized, double-blind study, 113 patients with a pruritus score 3 or 4 (1=absent; 2=mild, no treatment required; 3=moderate pruritus, treatment required; and 4=severe pruritus) after SA morphine 0.2 mg were assigned to group ondansetron, which received 4 mg intravenously (i....
Source: Acta Anaesthesiologica Scandinavica - March 15, 2010 Category: Anesthesiology Authors: S. M. SIDDIK-SAYYID, V. G. YAZBECK-KARAM, B. W. ZAHREDDINE, A. M. B. F. ADHAM, C. M. DAGHER, W. A. SAASOUH, M. T. AOUAD Source Type: journals

Can intraoperative TEE correctly measure residual shunt after surgical repair of ventricular septal defects?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion  TEE-derived Qp/Qs lacks the accuracy required to play a crucial role in quantitatively measuring the severity of residual shunt, while two-dimensional TEE can reliably detect residual leakage after VSD closure and lead to optimal judgment on the need for re-repair. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00540-010-0896-3Authors Satoshi Kurokawa, Tokyo Women’s Medical University Department of Anesthesiology, Faculty of Medicine 8-1 Kawadacho, Shinjuku-ku Tokyo 162-8666 JapanTakayuki Honma, Niigata University Department of Anesthesiology, Faculty of Medicine Niig...
Source: Journal of Anesthesia - March 14, 2010 Category: Anesthesiology Tags: Journal of Anesthesia Source Type: journals

Electroencephalographic response following midazolam-induced general anesthesia: relationship to plasma and effect-site midazolam concentrationsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion  Following the induction of general anesthesia with i.v. midazolam 0.2 or 0.3 mg kg−1, the BIS was positively correlated with the relative beta ratio. Despite a rapid decrease in the plasma and effect-site concentrations of midazolam, the average BIS remained >60 for 60 min after induction, reflecting an increased power of the electroencephalographic high-frequency band. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00540-010-0907-4Authors Wakako Miyake, Osaka City University Graduate School of Medicine Department of Anesthesiology 1-5-7 Asahimachi A...
Source: Journal of Anesthesia - March 14, 2010 Category: Anesthesiology Tags: Journal of Anesthesia Source Type: journals

Remifentanil versus fentanyl compared in a target-controlled infusion of propofol anesthesia: quality of anesthesia and recovery profileemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion  We concluded that in propofol-based TCI anesthesia under BIS supervision for septorhinoplasty operations, remifentanil was better than fentanyl, especially with respect to emergence from total intravenous anesthesia (TIVA). Furthermore, the durations of anesthesia and operation were rather short, which indicates that fentanyl can be safely used. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00540-010-0898-1Authors Demet Coskun, Gazi University Faculty of Medicine Department of Anesthesiology and Reanimation 06500 Ankara TurkeyHulya Celebi, Gazi University Faculty of Me...
Source: Journal of Anesthesia - March 14, 2010 Category: Anesthesiology Tags: Journal of Anesthesia Source Type: journals

Post-scan: another role of ultrasound in central venous catheter insertionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Content Type Journal ArticleCategory Letter to the EditorDOI 10.1007/s00540-010-0897-2Authors Akihiro Suzuki, Asahikawa Medical College Department of Emergence Medicine and Intensive Care 2-1-1-1 Midorigaoka Higashi Hokkaido 078-8510 JapanMai Kishi, Asahikawa Medical College Department of Anesthesiology and Critical Care Medicine Hokkaido 078–8510 JapanAtsushi Kurosawa, Asahikawa Medical College Department of Anesthesiology and Critical Care Medicine Hokkaido 078–8510 JapanHirotsugu Kanda, Asahikawa Medical College Department of Anesthesiology and Critical Care Medicine Hokkaido 078–8510 JapanTakayuki Kunisawa, A...
Source: Journal of Anesthesia - March 14, 2010 Category: Anesthesiology Tags: Journal of Anesthesia Source Type: journals

Malignant Hyperthermia Travel Award To San Diego, CAemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
MHAUS announces availability of a $1,500 Travel Award to anesthesia resident/fellow or anesthesiologist who is within five years of ending his/her training to attend the 2010 annual meeting of the American Society of Anesthesiologists in San Diego CA. The Daniel Massik Fund at The Foundation for Jewish Philanthropies in Buffalo, NY was established by Mr... (Source: Pain / Anesthetics News From Medical News Today)
Source: Pain / Anesthetics News From Medical News Today - March 14, 2010 Category: Anesthesiology Tags: Pain / Anesthetics Source Type: news

Shoulder pain in the adolescent athlete: a multidisciplinary diagnostic approach from the medical, surgical, and imaging perspectives.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This article is a compilation work authored by a pediatric radiologist, primary care pediatric sports medicine physician and pediatric orthopedic surgeon with the goal of providing a simplified diagnostic approach to the adolescent athlete presenting with shoulder pain. The spectrum of complex diagnoses often confused by innumerable radiologic acronyms can be distilled into common recognizable injury patterns. Once the physiology leading to the injury pattern is understood, the pediatric radiologist can perform a more focused imaging approach and provide a more meaningful interpretation to the referring orthopedic speciali...
Source: Pain Physician - March 14, 2010 Category: Anesthesiology Authors: Marshall KW, Marshall DL, Busch MT Tags: Pediatr Radiol Source Type: journals

Strong Period Pain And Excess Weight In Childhood Increase Risk Of Endometriosisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Queensland Institute of Medical Research (QIMR) scientists have identified a new link between strong period pain experienced in adolescence and early adulthood and the risk of endometriosis. Researchers from QIMR's Gynaecological Cancer Laboratory have found having strong period pain often at an early age doubles a woman's risk of developing endometriosis... (Source: Pain / Anesthetics News From Medical News Today)
Source: Pain / Anesthetics News From Medical News Today - March 13, 2010 Category: Anesthesiology Tags: Women's Health / Gynecology Source Type: news

[False positive death certification : Does the Lazarus phenomenon partly explain false positive death certification by rescue services in Germany, Austria and Switzerland?]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Apart from misdiagnosis, the Lazarus phenomenon, a spontaneous return of circulation after cardiac arrest, is a potential cause for false positive death certification. Because of medicolegal consequences and thus a negative publication bias, the incidence of false positive death certification is unknown. As a false positive death certification results in criminal prosecution and thus media interest, numerous media archives in Germany, Austria and Switzerland were searched for such reports. A total of nine cases of false positive death certification in these three countries were identified since the early 1990s of which...
Source: Der Anaesthesist - March 13, 2010 Category: Anesthesiology Authors: Herff H, Loosen SJ, Paal P, Mitterlechner T, Rabl W, Wenzel V Tags: Anaesthesist Source Type: journals

[Lazarus phenomenon : Spontaneous return of circulation after cardiac arrest and cessation of resuscitation attempts.]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSIONS: In the relevant medical literature, the Lazarus phenomenon is a rare occurrence. It seems to be a phenomenon which has often been described in non-medical literature but not published in medical literature. The pathophysiological mechanisms are poorly understood. In the literature several mechanisms are discussed which could be important for this phenomenon, e.g. autopositive end-expiratory pressure, hyperventilation and alkalosis, hyperkalemia, delayed action of drugs and unobserved minimal vital signs. In the literature it is recommended that patients should be passively monitored for at least 10 min after c...
Source: Der Anaesthesist - March 13, 2010 Category: Anesthesiology Authors: Wiese CH, Bartels UE, Orso S, Graf BM Tags: Anaesthesist Source Type: journals

[Patent blue V : Inert dye or potent allergen?]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Patent blue V is widely used as a food dye. Clinically, patent blue V dye has been increasingly used in oncological surgery to identify the sentinel lymph nodes in breast cancer and other malignancies. The case of a patient who developed severe anaphylactic shock to subcutaneous injection of patent blue V during breast surgery is presented. The clinical course and the anesthesiological management are presented, and the pitfalls that may delay the correct diagnosis are highlighted. PMID: 20224949 [PubMed - as supplied by publisher] (Source: Der Anaesthesist)
Source: Der Anaesthesist - March 13, 2010 Category: Anesthesiology Authors: Rogler V, Röhm C, Reutershan J Tags: Anaesthesist Source Type: journals

[Status asthmaticus : Role of extracorporeal lung assist procedures.]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The successful application of a pumpless extracorporeal lung assist procedure ("interventional lung assist, iLA) in three cases of severe refractory status asthmaticus, which could not be solved with conventional pharmacological and respiratory therapy is reported. After an individual risk-benefit analysis such a therapy can be used to reduce lung injury due to invasive mechanical ventilation. Because of the complexity of this therapy it should only be applied in special medical centers with sufficient experience in dealing with extracorporeal lung assist procedures. PMID: 20224950 [PubMed - as supplied by publishe...
Source: Der Anaesthesist - March 13, 2010 Category: Anesthesiology Authors: Aniset L, Kalenka A Tags: Anaesthesist Source Type: journals

[Quality of premedication and patient satisfaction after premedication with midazolam, clonidine or placebo : Randomized double-blind study with age-adjusted dosage.]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSION: Midazolam was the most anxiolytic, sedative and favored premedication with the least adverse effects. Most patients would choose midazolam next time. PMID: 20224951 [PubMed - as supplied by publisher] (Source: Der Anaesthesist)
Source: Der Anaesthesist - March 13, 2010 Category: Anesthesiology Authors: Zalunardo MP, Ivleva-Sauerborn A, Seifert B, Spahn DR Tags: Anaesthesist Source Type: journals

Proceedings of the Anaesthetic Research Society Meeting: The Royal College of Anaesthetists, London, UK * December 3-4, 2009email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: British Journal of Anaesthesia)
Source: British Journal of Anaesthesia - March 12, 2010 Category: Anesthesiology Tags: Abstracts Source Type: journals

Corrigendumemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: British Journal of Anaesthesia)
Source: British Journal of Anaesthesia - March 12, 2010 Category: Anesthesiology Tags: Corrigendum Source Type: journals

Current Topics in Pain: 12th World Congress on Painemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: British Journal of Anaesthesia)
Source: British Journal of Anaesthesia - March 12, 2010 Category: Anesthesiology Authors: Power, I. Tags: Book Reviews Source Type: journals

Cardiopulmonary Bypassemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: British Journal of Anaesthesia)
Source: British Journal of Anaesthesia - March 12, 2010 Category: Anesthesiology Authors: Smith, D. Tags: Book Reviews Source Type: journals

Case-Based Anesthesia: Clinical Learning Guidesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: British Journal of Anaesthesia)
Source: British Journal of Anaesthesia - March 12, 2010 Category: Anesthesiology Authors: Young, E. J. W. Tags: Book Reviews Source Type: journals