Anesthesiology Research This is an OPML file. It can be used to export all the MedWorm RSS feeds on this topic into your personal RSS reader (usually you have to save this file to your own computer before clicking on an Import OPML command in your own feed reader to upload the file which will then import all the feeds) or it can be used by webmasters to integrate MedWorm feeds with their own website. This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader, such as GoogleReader, or to display this data on your own website or blog. Subscribe to this data using MyMedWorm.Subscribe to this data using GoogleReader.Subscribe to this data using Bloglines.Subscribe to this data using MyYahoo.
This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 2.
Phacoemulsification under topical anaesthesia in remote areas: experiences in the Amazon
Despite many global initiatives to eliminate avoidable blindness, the number of cataract‐blind people is still unacceptably high in many parts of the world, particularly in remote rural areas of developing countries. One of the established ways to increase uptake of cataract services is by extending ophthalmic care facilities to rural areas through mobile eye units, thereby providing cataract surgical services close to large numbers of affected individuals.1,2 Unfortunately, however, results of camp surgery are often poor. 1,3 As a result, the quality and safety of surgery in eye camps is questioned 1, and a growing body...
Source: Clinical and Experimental Ophthalmology - January 21, 2013 Category: Opthalmology Authors: Janna Minderhoud, Jerrel C Pawiroredjo, Dennis RA Mans, Anne‐Marie T Bueno Mesquita‐Voigt, Peerooz Saeed Tags: Letter to the Editor Source Type: research
Pain assessment in neonates and infants in the post-operative period following cardiac surgery
Conclusions There was poor agreement between the COMFORT scale and CAAS for detection of pain in neonates and infants who had undergone cardiac surgery. A reduction in systemic systolic blood pressure and a rise in pulmonary artery pressure were observed during painful stimulation on the first post-operative day. For this population, a pain scale scoring physiological parameters according to their variation to higher and lower values should be developed.
Source: Postgraduate Medical Journal - January 21, 2013 Category: Journals (General) Authors: Cury, M. R. J., Martinez, F. E., Carlotti, A. P. C. P. Tags: Pain (neurology), Hypertension, Interventional cardiology, Pain (palliative care), Pain (anaesthesia), Mechanical ventilation, Drugs: musculoskeletal and joint diseases, Cardiothoracic surgery Original article Source Type: research
Incidence of neuraxial haematoma after total hip or knee surgery: RECORD programme (rivaroxaban vs. enoxaparin)
ConclusionAlthough no issues were observed with the use of neuraxial anaesthesia in this population of 4086 patients receiving rivaroxaban after total hip or knee replacement, it is important to remain aware of the risk of compressive haematoma. This may be of particular concern in elderly patients with renal insufficiency receiving an anticoagulant predominantly eliminated via the kidneys.
Source: Acta Anaesthesiologica Scandinavica - January 21, 2013 Category: Anesthesiology Authors: N. ROSENCHER, J. V. LLAU, W. MUECK, A. LOEWE, S. D. BERKOWITZ, M. HOMERING Tags: Original Article Source Type: research
Targeting Oxidative Injury and Cytokines' Activity in the Treatment with Anti‐Tumor Necrosis Factor‐α Antibody for Complex Regional Pain Syndrome 1
Abstract Cytokines and oxygen free radicals have been implicated in the potential pathogenic development of complex regional pain syndrome (CRPS). We aimed to analyze the relationship between clinical status, circulating levels of cytokines, and markers of oxidative damage during the treatment with anti‐TNFα antibodies. The patient chosen for treatment had not had improvement through a number of conventional therapies and fulfilled the current diagnostic criteria for CRPS‐1. We investigated the clinical variables before and after systemic administration of 1.4 mg/kg anti‐TNFα antibody (infliximab), repeated after ...
Source: Pain Practice - January 21, 2013 Category: Anesthesiology Authors: Adriana A. Miclescu, Lena Nordquist, Eva‐Britt Hysing, Stephen Butler, Samar Basu, Anne‐Li Lind, Torsten Gordh Tags: Clinical Report Source Type: research
Introducing Interventional Pain Services in a Large African Teaching Hospital: Challenges and Opportunities
Abstract There is a need for interventional pain management in the developing world; however, there are many barriers to the introduction of interventional pain therapies. This brief report describes one approach to the introduction of interventional pain medicine to a Nigerian teaching hospital. Although many barriers exist, interventional pain medicine can be brought to the developing world, as demonstrated in this case series.
Source: Pain Practice - January 21, 2013 Category: Anesthesiology Authors: Zakari Suleiman, Allen W. Burton Tags: Clinical Report Source Type: research
Acupuncture and Burning Mouth Syndrome: A Pilot Study
Abstract Burning mouth syndrome (BMS) is a chronic condition most common in middle‐aged and elderly women, with prevalence rates in the general population ranging from 0.5% to 5%. Defined by the International Headache Society as “an intraoral burning sensation for which no medical or dental cause can be found,” BMS is considered a form of neuropathic pain. The management of BMS remains unsatisfactory. In this pilot study, we investigated the use of acupuncture in a small group of BMS patients. The study group, after 4 refusals, was composed of 10 BMS patients (9 females and 1 male; mean age, 65.2 years; range, from ...
Source: Pain Practice - January 21, 2013 Category: Anesthesiology Authors: Andrea Sardella, Giovanni Lodi, Marco Tarozzi, Elena Varoni, Roberto Franchini, Antonio Carrassi Tags: Original Article Source Type: research
Neuropathic Pain with Features of Complex Regional Syndrome in the Upper Extremity after Herpes Zoster
We report a case of a 73‐year‐old female who developed unbearable neuropathic pain after a herpes zoster episode. The pain persisted and could not be controlled despite multimodal analgesia. In addition to postherpetic neuralgia, myelitis and complex regional pain syndrome were diagnosed during the evolution of neuropathic pain. This complex neuropathic pain was resolved after sympathetic ganglion block.
Source: Pain Practice - January 21, 2013 Category: Anesthesiology Authors: Marc Giménez‐Milà, Carme Busquets, Antonio Ojeda, Adela Faulí, Luis Alfonso Moreno, Sebastian Videla Tags: Clinical Report Source Type: research
National risk prediction model for elective abdominal aortic aneurysm repair
Conclusion:This multivariable model for elective AAA repair can be used to risk‐adjust outcome analyses and provide patient‐specific estimates of in‐hospital mortality risk for open AAA repair or EVAR. Copyright © 2013 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
Source: British Journal of Surgery - January 21, 2013 Category: Surgery Authors: S. W. Grant, G. L. Hickey, A. D. Grayson, D. C. Mitchell, C. N. McCollum Tags: Original Article Source Type: research
Randomized clinical trial of the impact of insulin therapy on liver function in patients undergoing major liver resection
Conclusion:The glucose–insulin protocol reduced postoperative liver dysfunction and improved liver glycogen content. Registration number: NCT00774098 (http://www.clinicaltrials.gov). Copyright © 2013 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
Source: British Journal of Surgery - January 21, 2013 Category: Surgery Authors: M. Hassanain, P. Metrakos, A. Fisette, S. A. R. Doi, T. Schricker, R. Lattermann, G. Carvalho, L. Wykes, H. Molla, K. Cianflone Tags: Randomized Clinical Trial Source Type: research
Development of a multi-electrode array for spinal cord epidural stimulation to facilitate stepping and standing after a complete spinal cord injury in adult rats
Conclusions: Therefore the high density electrode array allows high spatial resolution and the ability to selectively activate different neural pathways within the lumbosacral region of the spinal cord to facilitate standing and stepping in adult spinal rats and provides the capability to evoke motor potentials and thus a means for assessing connectivity between sensory circuits and specific motor pools and muscles.
Source: Journal of NeuroEngineering and Rehabilitation - January 21, 2013 Category: Rehabilitation Authors: Parag GadJaehoon ChoeMandheerej NandraHui ZhongRoland RoyYu-Chong TaiV Edgerton Source Type: research
QT Prolongation and T‐Wave Alternans during Catheter Ablation of Atrial Fibrillation: A Case Report
We report a case of a 63‐year‐old woman who developed profound QT prolongation, T‐wave alternans, and spontaneous ventricular fibrillation during catheter ablation of atrial fibrillation. A thorough search into the possible mechanisms identified the use of sevoflurane, an inhalational gas anesthetic as the culprit. The patient was converted to propofol anesthesia and her QT interval normalized promptly.
Source: Annals of Noninvasive Electrocardiology - January 20, 2013 Category: Cardiology Authors: Aditya Saini, Hemal Shah, Samir Saba Tags: Case Report Source Type: research
A prospective study of early removal of the urethral catheter after colorectal surgery in patients having epidural analgesia as part of the Enhanced Recovery After Surgery programme
ConclusionEarly TWOC with epidural analgesia running significantly increases the risk of urinary retention, however it was still successful in 88% of patients.© 2013 The Authors. Colorectal Disease © 2013 The Association of Coloproctology of Great Britain and Ireland
Source: Colorectal Disease - January 19, 2013 Category: Gastroenterology Authors: Benjamin M Stubbs, Kathrine JM Badcock, Catherine Hyams, Faira E Rizal, Steve Warren, Daren Francis Tags: Original Article Source Type: research
Effects of microcurrent stimulation on Hyaline cartilage repair in immature male rats (Rattus norvegicus)
Conclusion: We conclude that microcurrent stimulation accelerates the cartilage repair in non-articular site from prepuberal animals.
Source: BMC Complementary and Alternative Medicine - January 19, 2013 Category: Complementary Medicine Authors: Carla de Campos CicconeDenise ZuzziLia NevesJosué MendonçaPaulo JoazeiroMarcelo Esquisatto Source Type: research
A comparison of cardiopulmonary and anesthetic effects of an induction dose of alfaxalone or propofol in dogs
Conclusions and clinical relevanceThere were no clinically significant differences in cardiopulmonary effects between propofol and alfaxalone. A single bolus of propofol resulted in shorter recovery times and fewer adverse events than a single bolus of alfaxalone.
Source: Veterinary Anaesthesia and Analgesia - January 19, 2013 Category: Veterinary Research Authors: Jill K Maney, Molly K Shepard, Christina Braun, Jeannette Cremer, Erik H Hofmeister Tags: Research Paper Source Type: research
Association of partial pressure of carbon dioxide in expired gas and arterial blood at three different ventilation states in apneic chickens (Gallus domesticus) during air sac insufflation anesthesia
ConclusionsMeasured PĒCO2 cannot be used in a simple linear fashion to predict PaCO2 in birds during air sac insufflation anesthesia. The PĒCO2 at which apnea occurs during air sac insufflation anesthesia is not predictable. Clinical relevanceArterial blood gases should be used to monitor CO2 during air sac insufflation anesthesia to verify appropriate patient ventilation.
Source: Veterinary Anaesthesia and Analgesia - January 19, 2013 Category: Veterinary Research Authors: Monique Paré, John W Ludders, Hollis N Erb Tags: Research Paper Source Type: research
Quadriplegia in a child following adenotonsillectomy
We report the case of a child who, following adentonsillectomy, developed quadriplegia and acute respiratory distress due to previously undetected atlanto‐axial instability. Patients with atlanto‐axial instability often have mild or non‐specific symptoms, despite severe cervical cord compression. Subtle manifestations may be ignored or attributed to other disease processes, which render patients with undiagnosed atlanto‐axial instability at risk of serious neurological injury during general anaesthesia, particularly at the time of laryngoscopy and tracheal intubation.
Source: Anaesthesia - January 18, 2013 Category: Anesthesiology Authors: J. Agarwal, M. S. Tandon, D. Singh, P. Ganjoo Tags: Case Report Source Type: research
Potassium‐induced cortical spreading depression bilaterally suppresses the electroencephalogram but only ipsilaterally affects red blood cell velocity in intraparenchymal capillaries
Abstract Cortical spreading depression (CSD) is a repetitive, propagating profile of mass depolarization of neuronal and glial cells, followed by sustained suppression of spontaneous neuronal activity. We have reported a long‐lasting suppressive effect on red blood cell (RBC) velocities in intraparenchymal capillaries. Here, to test the hypothesis that the prolonged decrease of RBC velocity in capillaries is due to suppression of neuronal activity, we measured CSD‐elicited changes in the electroencephalogram (EEG) as an index of neuronal activity. In isoflurane‐anesthetized rats, DC potential, EEG, partial pressure o...
Source: Journal of Neuroscience Research - January 18, 2013 Category: Neuroscience Authors: Miyuki Unekawa, Yutaka Tomita, Haruki Toriumi, Kazuto Masamoto, Iwao Kanno, Norihiro Suzuki Tags: Research Article Source Type: research
Impaired Contractile Recovery after Low-Flow Myocardial Ischemia in a Porcine Model of Metabolic Syndrome.
Conclusion: Pigs with characteristics of metabolic syndrome demonstrate impaired contractile and metabolic recovery after low-flow myocardial ischemia. Contributory mechanisms may include remodeling of cardiolipin, abnormal activation of Akt, and excessive utilization of fatty acid substrate. PMID: 23335793 [PubMed - as supplied by publisher]
Source: American Journal of Physiology. Heart and Circulatory Physiology - January 18, 2013 Category: Physiology Authors: Huang JV, Lu L, Ye S, Bergman BC, Sparagna GC, Sarraf M, Reusch JE, Greyson CR, Schwartz GG Tags: Am J Physiol Heart Circ Physiol Source Type: research
[Correspondence] Anaesthetic-related mortality in sub-Saharan Africa – Authors' reply
Gregor Pollach raises some excellent points about the limitations inherent in the published evidence base for anaesthetic-related mortality in developing countries. Relative to developed countries, there are precious few published studies on this issue from the lowest-income countries. We would like to see more attention placed on perioperative mortality, and would like to support increased awareness of the need for more studies in this area.
Source: LANCET - January 17, 2013 Category: Journals (General) Authors: Daniel Bainbridge, Janet Martin, Miguel Arango, Davy Cheng Tags: Correspondence Source Type: research
[Correspondence] Anaesthetic-related mortality in sub-Saharan Africa
In their systematic review and meta-analysis, Daniel Bainbridge and colleagues (Sept 22, p 1075) assess anaesthetic-related mortality in developed and developing countries. From the perspective of the anaesthesia department of a large sub-Saharan hospital in one of the poorest countries on earth, I feel that three additions might help to understand certain challenges.
Source: LANCET - January 17, 2013 Category: Journals (General) Authors: Gregor Pollach Tags: Correspondence Source Type: research
Stellate Ganglion Block as an Early Intervention in Sympathetically Maintained Headache and Orofacial Pain Caused by Temporal Arteritis
Conclusion.This case demonstrates that SGB may relieve pain related to temporal arteritis and sympathetically maintained headache and orofacial pain by reducing noxious stimulation peripherally and decreasing central pain transmission centrally.
Source: Pain Medicine - January 17, 2013 Category: Anesthesiology Authors: Noboru Noma, Hiroshi Kamo, Yuka Nakaya, Ko Dezawa, Andrew Young, Junad Khan, Yoshiki Imamura Tags: Case Report Source Type: research
Thoracic Endovascular Repair for Aorto-Esophageal Fistula in Patients With Esophageal Carcinoma: Report of 3 Cases
Aorto-esophageal fistula (AEF) is a rare complication of esophageal carcinoma. Left untreated, it may be lethal due to massive upper gastrointestinal bleeding, while open thoracic surgery is associated with high operative mortality and morbidity. In contrast, thoracic endovascular aortic repair (TEVAR) for AEF is less invasive than open thoracic surgery. Here, we report 3 successful cases of AEF with esophageal carcinoma treated using TEVAR under local anesthesia in the emergent or urgent phase. General condition of all the patients was dramatically improved, but 1 patient with exsanguinations developed infection of the im...
Source: Vascular and Endovascular Surgery - January 17, 2013 Category: Surgery Authors: Ishikawa, N., Maruta, K., Oi, M., Iizuka, H., Kawaura, H., Omoto, T. Tags: Case Reports Source Type: research
Delineating the role of multiple intra‐articular corticosteroid injections in the management of juvenile idiopathic arthritis in the biologic era
Conclusion.Multiple IAC therapy induced sustained remission of joint synovitis in a substantial proportion of patients. A controlled trial comparing multiple IAC therapy and methotrexate versus methotrexate and a tumor necrosis factor antagonist is worthy of consideration. © 2013 by the American College of Rheumatology
Source: Arthritis Care and Research - January 17, 2013 Category: Rheumatology Authors: Charalampia Papadopoulou, Mikhail Kostik, Maria Isabel Gonzalez‐Fernandez, Marek Bohm, Juan Carlos Nieto‐Gonzalez, Angela Pistorio, Stefano Lanni, Alessandro Consolaro, Alberto Martini, Angelo Ravelli Tags: Original Article Source Type: research
Pseudo ( Platelet-type) von Willebrand disease in pregnancy : a case report
Conclusion: Management of pseudo von Willebrand disease in pregnancy involves the co-operation of multidisciplinary teams, regular monitoring of platelet levels and factor VIII and replacement as appropriate. This case report highlights this rare condition and the need to exclude all the other differential diagnoses of thrombocytopenia in pregnant women with thrombocytopenia.
Source: BMC Pregnancy and Childbirth - Latest articles - January 17, 2013 Category: OBGYN Authors: Neetu GroverVincent BoamaMunazzah Chou Source Type: research
The use of 2‐chloroprocaine for spinal anaesthesia
Spinal anaesthesia is a safe and reliable anaesthetic modality for surgical procedures on the lower part of the body. However, because of the description of transient neurologic symptoms (TNS), most practitioners have abandoned intrathecal lidocaine. Chloroprocaine (2‐chloroprocaine, CP) has been one candidate to replace lidocaine for short procedures, despite the fact that neurologic sequelae have been described following the intrathecal injection of large doses of preservative‐containing CP intended for epidural use. The National Library of Medicine's Medline and the EMBASE databases were searched for the time period...
Source: Acta Anaesthesiologica Scandinavica - January 16, 2013 Category: Anesthesiology Authors: E. GOLDBLUM, A. ATCHABAHIAN Tags: Review Article Source Type: research
The use of local anaesthesia in haemorrhoidal banding: a randomised controlled trial
ConclusionLocal anesthetic injection at the time of banding is simple and safe. It may reduce patient discomfort following banding of haemorrhoids.© 2012 The Authors. Colorectal Disease © 2012 The Association of Coloproctology of Great Britain and Ireland
Source: Colorectal Disease - January 16, 2013 Category: Gastroenterology Authors: Henry CK Kwok, Sophie E Noblett, Natasha EA Murray, Arend EH Merrie, Julian L Hayes, Ian P Bissett Tags: Original Article Source Type: research
Effects of ρ‐Da1a a peptidic α1A‐adrenoceptor antagonist in human isolated prostatic adenoma and anaesthetized rats
Conclusions and Implicationsρ‐Da1a exhibited a relevant effect on IUP and a small effect on AP. In contrast, tamsulosin antagonized the effects of PHE on both IUP and AP. We conclude that ρ‐Da1a is more uroselective than tamsulosin. ρ‐Da1a is the most selective peptidic antagonist for α1A‐adenoceptors identified to date and could be a new treatment for various urological diseases.
Source: British Journal of Pharmacology - January 16, 2013 Category: Drugs & Pharmacology Authors: S Palea, A Maiga, V Guilloteau, M Rekik, M Guérard, C Rouget, P Rischmann, H Botto, P Camparo, P Lluel, N Gilles Tags: RESEARCH PAPER Source Type: research
Preoperative Assessment and Perioperative Management of Cardiovascular Risk
Preoperative cardiovascular evaluation of patients scheduled to undergo surgery requires a multidisciplinary approach involving anesthetists, surgeons, and cardiologists. Within the last 5 to 10 years, there have been considerable scientific advances in this field, and the European Society of Cardiology (ESC) and the American College of Cardiology/American Heart Association(ACC/AHA) have updated their guidelines.1,11 Greater emphasis now lies on preoperative clinical risk stratification and less on routine cardiac testing. Prophylactic coronary revascularization is now also seen as rarely indicated simply to lower the risk...
Source: Angiology - January 16, 2013 Category: Cardiology Authors: Schiefermueller, J., Myerson, S., Handa, A. I. Tags: Risk Factors Source Type: research
Association of medical student burnout with residency specialty choice
Conclusions Specialty choices regarding lifestyle controllability and income were associated with the amount and type of medical school burnout, as well as with lifestyle‐, prestige‐ and patient care‐related motivation. Given that burnout may influence specialty choice, particularly with regard to the primary care specialties, medical schools may consider the utility of burnout prevention strategies.
Source: Medical Education - January 16, 2013 Category: Universities & Medical Training Authors: Lindsey Enoch, John T Chibnall, Debra L Schindler, Stuart J Slavin Tags: student and specialty choice Source Type: research
Drug choice for ambulatory anaesthesia: a matter of personal preferences
Source: Acta Anaesthesiologica Scandinavica - January 16, 2013 Category: Anesthesiology Authors: M. BRATTWALL, M. W. STOMBERG, J. JAKOBSSON Tags: Letter to the Editor Source Type: research
Heparin‐binding protein (HBP): an early marker of respiratory failure after trauma?
ConclusionHBP is a potential biomarker candidate for early detection of ARDS development after trauma. Further research is required to confirm a casual relationship between plasma HBP and the development of ARDS.
Source: Acta Anaesthesiologica Scandinavica - January 16, 2013 Category: Anesthesiology Authors: J. JOHANSSON, O. BRATTSTRÖM, F. SJÖBERG, L. LINDBOM, H. HERWALD, E. WEITZBERG, A. OLDNER Tags: Original Article Source Type: research
Comparisons of perioperative outcomes and costs between open and laparoscopic radical prostatectomy: A propensity‐score matching analysis based on the Japanese Diagnosis Procedure Combination database
In conclusion, these findings confirm several benefits of laparoscopy over open approach for radical prostatectomy.
Source: International Journal of Urology - January 16, 2013 Category: Urology & Nephrology Authors: Toru Sugihara, Hideo Yasunaga, Hiromasa Horiguchi, Nobuo Tsuru, Hiroyuki Ihara, Tetsuya Fujimura, Hiroaki Nishimatsu, Kazuhiko Ohe, Kiyohide Fushimi, Yukio Homma Tags: Short Communication Source Type: research
Minimum alveolar concentration (MAC) for sevoflurane and xenon at normothermia and hypothermia in newborn pigs
ConclusionIn newborn swine sevoflurane, MAC was temperature dependent, while xenon MAC was independent of temperature. There was large individual variability in xenon MAC, from 60% to 120%.
Source: Acta Anaesthesiologica Scandinavica - January 15, 2013 Category: Anesthesiology Authors: X. LIU, J. DINGLEY, M. ELSTAD, E. SCULL‐BROWN, P. A. STEEN, M. THORESEN Tags: Original Article Source Type: research
Patient and doctor attitudes and beliefs concerning perioperative do not resuscitate orders: anesthesiologists¿ growing compliance with patient autonomy and self determination guidelines
Background: In 1993, the American Society of Anesthesiologists (ASA) published guidelines stating that automatic perioperative suspension of Do Not Resuscitate (DNR) orders conflicts with patients’ rights to self-determination. Almost 20 years later, we aimed to explore both patient and doctor views concerning perioperative DNR status. Methods: Five-hundred consecutive patients visiting our preoperative evaluation clinic were surveyed and asked whether they had made decisions regarding resuscitation and to rate their agreement with several statements concerning perioperative resuscitation. Anesthesiologists, surgeons a...
Source: BMC Anesthesiology - January 15, 2013 Category: Anesthesiology Authors: Christopher BurkleKeith SwetzMatthew ArmstrongMark Keegan Source Type: research
Effects of ACE inhibition and ANG II stimulation on renal Na-Cl cotransporter distribution, phosphorylation, and membrane complex properties
This study aimed to determine whether NCC phosphorylation (NCCp) was regulated by acute (20–30 min) treatment with the ACEI captopril (12 μg/min x 20 min) or by a sub-pressor dose of ANG II (20 ng·kg–1·min–1) in Inactin-anesthetized rats. By immuno-EM, NCCp was detected exclusively in or adjacent to apical plama membranes (APM) in controls and after ACEI or ANG II treatment, while NCC total was detected in both APM and subapical cytoplasmic vesicles (SCV) in all conditions. In renal homogenates, neither ACEI nor ANG II treatment altered NCCp abundance, assayed by immunoblot. However, by d...
Source: AJP: Cell Physiology - January 15, 2013 Category: Cytology Authors: Lee, D. H., Maunsbach, A. B., Riquier-Brison, A. D., Nguyen, M. T. X., Fenton, R. A., Bachmann, S., Yu, A. S., McDonough, A. A. Tags: ARTICLES Source Type: research
The administration of anesthetic in the thyroid pericapsular region increases the possibility of side effects during percutaneous laser photocoagulation of thyroid nodules
ConclusionsThe results of our study demonstrate that the injection of local anesthetic does not help reduce nodule volume and that side effects (fever and pain) increase about threefold in the early hours following LA treatment. Thus, we do not recommend local anesthesia before LA of thyroid nodules. Lasers Surg. Med. © 2013 Wiley Periodicals, Inc.
Source: Lasers in Surgery and Medicine - January 15, 2013 Category: Laser Surgery Authors: Giovanni Gambelunghe, Vittorio Bini, Massimo Monacelli, Nicola Avenia, Michele D'Ajello, Renato Colella, Pierpaolo De Feo Tags: Clinical Report Source Type: research
Quantitative near infrared spectroscopic analysis of Q‐Switched Nd:YAG treatment of generalized argyria
ConclusionQS 1,064 nm laser treatment of argyria is a viable method to restore normal skin pigmentation with no evidence of recurrence over study period. Quantitative spectroscopic measurements: (1) confirmed dyspigmentation was due to silver, (2) validated our clinical assessment of no recurrence up to 1‐year post‐treatment, and (3) indicated no collateral tissue damage with treatments. Lasers Surg. Med. © 2013 Wiley Periodicals, Inc.
Source: Lasers in Surgery and Medicine - January 15, 2013 Category: Laser Surgery Authors: Rolf B. Saager, Khaled M. Hassan, Clement Kondru, Anthony J. Durkin, Kristen M. Kelly Tags: Basic Science Source Type: research
Intrafascicular stimulation of monkey arm nerves evokes coordinated grasp and sensory responses
In this study, we implanted Utah Slanted Electrode Arrays (USEAs) intrafascicularly at the elbow or shoulder in arm nerves of rhesus monkeys (n = 4) under isoflurane anesthesia. Input-output curves indicated that pulse-width-modulated single-electrode stimulation in each arm nerve could recruit single muscles with little or no recruitment of other muscles. Stimulus trains evoked specific, natural, hand movements, which could be combined via multielectrode stimulation to elicit coordinated power or pinch grasp. Stimulation also elicited short-latency evoked potentials (EPs) in primary somatosensory cortex, which might be us...
Source: Journal of Neurophysiology - January 15, 2013 Category: Neurology Authors: Ledbetter, N. M., Ethier, C., Oby, E. R., Hiatt, S. D., Wilder, A. M., Ko, J. H., Agnew, S. P., Miller, L. E., Clark, G. A. Tags: Innovative Methodology Source Type: research
Deep brain stimulation of the substantia nigra pars reticulata improves forelimb akinesia in the hemiparkinsonian rat
In this study, we assessed whether stimulation of the substantia nigra pars reticulata (SNr) improved motor function. Hemiparkinsonian rats predominantly touched with their unimpaired forepaw >90% of the time in the stepping and limb-use asymmetry tests. After SNr-HFS (150 Hz), rats touched equally with both forepaws, similar to naive and sham-lesioned rats. In vivo, SNr-HFS decreased beta oscillations (12–30 Hz) in the SNr of freely moving hemiparkinsonian rats and decreased SNr neuronal spiking activity from 28 ± 1.9 Hz before stimulation to 0.8 ± 1.9 Hz during DBS in anesthetized animals; also, ne...
Source: Journal of Neurophysiology - January 15, 2013 Category: Neurology Authors: Sutton, A. C., Yu, W., Calos, M. E., Smith, A. B., Ramirez-Zamora, A., Molho, E. S., Pilitsis, J. G., Brotchie, J. M., Shin, D. S. Tags: Articles Source Type: research
(-)-Epicatechin administration and exercising skeletal muscle vascular control and microvascular oxygenation in healthy rats
Consumption of the dietary flavanol (–)-epicatechin (EPI) is associated with enhanced endothelial function and augmented skeletal muscle capillarity and mitochondrial volume density. The potential for EPI to improve peripheral vascular function and muscle oxygenation during exercise is unknown. We tested the hypothesis that EPI administration in healthy rats would improve treadmill exercise performance secondary to elevated skeletal muscle blood flow and vascular conductance [VC, blood flow/mean arterial pressure (MAP)] and improved skeletal muscle microvascular oxygenation. Rats received water (control, n = 12) or 4...
Source: AJP: Heart and Circulatory Physiology - January 15, 2013 Category: Cardiology Authors: Copp, S. W., Inagaki, T., White, M. J., Hirai, D. M., Ferguson, S. K., Holdsworth, C. T., Sims, G. E., Poole, D. C., Musch, T. I. Tags: VASCULAR BIOLOGY AND MICROCIRCULATION Source Type: research
Increased renal sympathetic nerve activity leads to hypertension and renal dysfunction in offspring from diabetic mothers
The exposure of the fetus to a hyperglycemic environment promotes the development of hypertension and renal dysfunction in the offspring at adult age. We evaluated the role of renal nerves in the hypertension and renal changes seen in offspring of diabetic rats. Diabetes was induced in female Wistar rats (streptozotocin, 60 mg/kg ip) before mating. Male offspring from control and diabetic dams were studied at an age of 3 mo. Systolic blood pressure measured by tail cuff was increased in offspring of diabetic dams (146 ± 1.6 mmHg, n = 19, compared with 117 ± 1.4 mmHg, n = 18, in controls). Renal function, base...
Source: AJP: Renal Physiology - January 15, 2013 Category: Urology & Nephrology Authors: de Almeida Chaves Rodrigues, A. F., de Lima, I. L. B., Bergamaschi, C. T., Campos, R. R., Hirata, A. E., Schoorlemmer, G. H. M., Gomes, G. N. Tags: ARTICLES Source Type: research
Bronchial balloon occlusion in children with complex pulmonary air leaks
Pulmonary air leaks in children are most commonly due to infection or barotrauma. While cases of severe barotrauma are falling because of advances in neonatal care, the incidence of necrotising pneumonia is rising. The majority of air leaks can be managed conservatively, but more severe cases pose a significant challenge to the clinician. The use of occlusive endobronchial balloons is an established anaesthetic technique for a number of indications, but is not widely used in children. We conducted a review over a 12-year period, and report six cases of complex air leaks in which balloon occlusion was used. Balloon occlusio...
Source: Archives of Disease in Childhood - January 15, 2013 Category: Pediatrics Authors: Hathorn, C., Armitage, N., Wensley, D., Seear, M. Tags: Pneumonia (infectious disease), TB and other respiratory infections, Pneumonia (respiratory medicine), Trauma, Injury Case reports Source Type: research
Response to Letter by Dr. Ruan
Source: Pain Medicine - January 15, 2013 Category: Anesthesiology Authors: Beatrice Setnik, Carl L. Roland, Lynn Webster Tags: LETTER TO THE EDITOR Source Type: research
A Feasibility Study of Transdermal Buprenorphine Versus Transdermal Fentanyl in the Long‐Term Management of Persistent Non‐Cancer Pain
ConclusionThirty percent of the total number of patients discontinued treatment because of side effects or unsatisfactory pain relief. For those continuing treatment, clinical improvements were seen in the initial 6 months in both groups. Fifty percent of the TDB and 43% of TDF groups had significant relief in 3 months, which persisted up to 6 months. Only 11% and 13% of patients, respectively, had sustained relief after 6 months. Twenty percent more patients in the TDB group benefited significantly in symptoms of depression from TDB compared with the TDF group. Interestingly, switching of patches seemed to increase accept...
Source: Pain Medicine - January 15, 2013 Category: Anesthesiology Authors: Farzana Mitra, Shahead Chowdhury, Mike Shelley, Gary Williams Tags: Original Research Article Source Type: research
Headline: Your Attendance at the 29th Annual Meeting Is Vital—Now More Than Ever!
Source: Pain Medicine - January 15, 2013 Category: Anesthesiology Authors: Martin Grabois Tags: PRESIDENT'S MESSAGE Source Type: research
What Would Bonica Say? A Word on the DVPRS Validation Study
Source: Pain Medicine - January 15, 2013 Category: Anesthesiology Authors: Alex Cahana Tags: EDITORIAL Source Type: research
Patient and doctor attitudes and beliefs concerning perioperative do not resuscitate orders: anesthesiologists' growing compliance with patient autonomy and self determination guidelines
Conclusions: Although many patients agree that their DNR orders should be suspended for their operation, they expect a discussion regarding the performance and nature of perioperative resuscitation. In contrast to previous studies, anesthesiologists were least likely to automatically suspend a DNR order.
Source: BMC Anesthesiology - January 15, 2013 Category: Anesthesiology Authors: Christopher BurkleKeith SwetzMatthew ArmstrongMark Keegan Source Type: research
While pain is neither uncommon nor novel, the concept of central pain (CP) has only recently become a prominent concern in the medical literature. CP results from lesions to the central nervous system caused by conditions such as stroke, multiple sclerosis, epilepsy, Parkinson's disease, and brain and spinal cord injuries. With the incidence of disability from these conditions increasing dramatically worldwide, it is no surprise that the diagnosis and treatment of CP are of growing interest in the fields of pain management, neurology, neurosurgery, and anesthesiology. However, inconsistent and contradictory reporting has e...
Source: Journal of the Neurological Sciences - January 14, 2013 Category: Neurology Authors: Aimee L. Alphonso, Jack W. Tsao Tags: Book Reviews Source Type: research