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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 12.

Pregabalin for acute and chronic pain in adultsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Source: Cochrane Library Area: Evidence > Drug Specific Reviews Background Antiepileptic drugs have been used in pain management since the 1960s. Pregabalin is a recently developed antiepileptic drug also used in management of chronic neuropathic pain conditions.   Objectives To assess analgesic efficacy and associated adverse events of pregabalin in acute and chronic pain.   Search strategy We searched MEDLINE, EMBASE, and CENTRAL to May 2009 for randomised controlled trials (RCTs). Additional studies were identified from the reference lists of retrieved papers and on-line clinical trial databases. &n...
Source: NeLM - Pain control - October 12, 2009 Category: Anesthesiology Source Type: organizations

misoprostol, Cytotecemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Title: misoprostol, CytotecCategory: MedicationsCreated: 12/31/1997Last Editorial Review: 10/12/2009
Source: MedicineNet Chronic Pain General - October 12, 2009 Category: Anesthesiology Source Type: consumer

etidronate, Didronelemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Title: etidronate, DidronelCategory: MedicationsCreated: 12/31/1997Last Editorial Review: 10/12/2009
Source: MedicineNet Chronic Pain General - October 12, 2009 Category: Anesthesiology Source Type: consumer

meclofenamate, Meclomenemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Title: meclofenamate, MeclomenCategory: MedicationsCreated: 12/31/1997Last Editorial Review: 10/12/2009
Source: MedicineNet Chronic Pain General - October 12, 2009 Category: Anesthesiology Source Type: consumer

fenoprofen, Nalfonemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Title: fenoprofen, NalfonCategory: MedicationsCreated: 12/31/1997Last Editorial Review: 10/12/2009
Source: MedicineNet Chronic Pain General - October 12, 2009 Category: Anesthesiology Source Type: consumer

estropipate, Ogenemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Title: estropipate, OgenCategory: MedicationsCreated: 3/26/1998 2:30:00 PMLast Editorial Review: 10/12/2009
Source: MedicineNet Chronic Pain General - October 12, 2009 Category: Anesthesiology Source Type: consumer

Vitamin D Good for Breast Cancer Patientsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Title: Vitamin D Good for Breast Cancer PatientsCategory: Health NewsCreated: 10/9/2009 12:10:00 PMLast Editorial Review: 10/12/2009
Source: MedicineNet Chronic Pain General - October 12, 2009 Category: Anesthesiology Source Type: consumer

Coach K: Osteoarthritis Can Be Beatenemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Title: Coach K: Osteoarthritis Can Be BeatenCategory: Health NewsCreated: 10/12/2009 8:10:00 AMLast Editorial Review: 10/12/2009
Source: MedicineNet Chronic Pain General - October 12, 2009 Category: Anesthesiology Source Type: consumer

Response to Cicero et al.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Opioid use in non-cancer pain is an important subject for all involved in chronic pain management. Descriptive surveys of opioid use by this patient group in different geographical territories show big differences in use. This is not surprising, because opioid use is subject to major medical, political and social influences. An example of the disparity is evident comparing the data in Cicero et al.’s paper with that reported in Pain from Denmark in 2003 by Eriksen and colleagues (Pain 106 (2003) 221–228 [Table 7]). Extrapolating from their survey results, Eriksen et al. concluded that 3% of the general population was t...
Source: Pain - October 12, 2009 Category: Anesthesiology Authors: Henry McQuay, R. Andrew Moore Tags: Letters to the Editor Source Type: journals

Noninvasive cardiac output and blood pressure monitoring cannot replace an invasive monitoring system in critically ill patientsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion Although the noninvasive CO measurement appears promising, the noninvasive blood pressure assessment is clearly less reliable than the invasively measured blood pressure. Therefore, according to the present data application of the Nexfin HD monitoring system in the ICU cannot be recommended generally. Whether such a tool might be reliable in certain critically ill patients remains to be determined.
Source: BMC Anesthesiology - October 11, 2009 Category: Anesthesiology Authors: John StoverReto StockerRenato LenherrThomas NeffSilvia CottiniBernhard ZollerMarkus Bechir Source Type: journals

'Use of winged laryngoscope blade for endotracheal intubation in a cleft lip child'– a case seriesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Source: Pediatric Anesthesia - October 11, 2009 Category: Anesthesiology Authors: Dhulkhed Vithal, Desai Nitish, Gupta Arun Kumar Source Type: journals

Sevoflurane-induced post-conditioning has no beneficial effects on neuroprotection after incomplete cerebral ischemia in ratsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The aim of this study was to investigate whether sevoflurane-induced post-conditioning has a neuroprotective effect against incomplete cerebral ischemia in rats. After cerebral ischemia by right common carotid artery occlusion in combination with hemorrhagic hypotension (35 mmHg) for 30 min, 1.0 minimum alveolar concentration of sevoflurane was administered for 15 min (Post-C 15, n=8), 30 min (Post-C 30, n=8), or 60 min (Post-C 60, n=8) in rats. Sevoflurane was not administered in control (n=8) and sham control rats (n=8). Neurologic evaluations were performed at 24, 48, and 72 h after ischemia. Degrees of neuronal damage ...
Source: Acta Anaesthesiologica Scandinavica - October 10, 2009 Category: Anesthesiology Authors: H.-M. LEE, D.-H. LEE, J.-H. CHOI, S.-R. LEE, Y.-W. KIM, D.-L. JEE, H.-S. DO, H.-M. LEE, S.-J. PARK Source Type: journals

A comparison of a flexometallic tracheal tube with the intubating laryngeal mask tracheal tube for nasotracheal fibreoptic intubation using the two-scope technique*email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We compared the incidence and site of impingement of a flexometallic tracheal tube with those of the re-usable intubating laryngeal mask (ILMA) tube in 60 anaesthetised patients undergoing nasotracheal fibreoptic intubation for oral surgery. A two-scope technique was used, observing the site of impingement with one scope whilst intubating with the other. The tubes were 6.0-mm in females and 6.5-mm in males. Impingement occurred with 10 (33%) flexometallic and 2 (7%) ILMA tubes (p < 0.032). In all but one case, the impingement was posterior to the right arytenoid cartilage. When impingement was observed, a single disempacti...
Source: Anaesthesia - October 9, 2009 Category: Anesthesiology Authors: M. R. Rai, S. H. Scott, A. G. Marfin, M. T. Popat, J. J. Pandit Source Type: journals

[Coagulation management in the treatment of multiple trauma.]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In recent years a new understanding of trauma-associated hemorrhaging and trauma-induced coagulopathy has been achieved. This coagulopathy is multifactorial with the predominant mechanisms being tissue trauma, shock and hypoperfusion which can lead to hyperfibrinolysis by activation of the endothelium. Routinely tested coagulation parameters, such as prothrombin time and partial thromboplastin time, are frequently employed for decision making but remain problematic as they do not give any information on clot stability, lysis or platelet function. Thrombelastometry seems to be a useful alternative. A pro-active anticipa...
Source: Der Anaesthesist - October 9, 2009 Category: Anesthesiology Authors: Lier H, Krep H, Schöchl H Tags: Anaesthesist Source Type: journals

Dexamethasone decreases oxycodone consumption following osteotomy of the first metatarsal bone: a randomized controlled trial in day surgeryemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Dexamethasone may improve multimodal pain management following painful orthopedic day surgery procedures, and decrease the need for post-operative opioids. We hypothesized that dexamethasone would reduce the need for oxycodone after surgical correction of hallux valgus. Sixty patients planned to undergo unilateral osteotomy of the first metatarsal as a day surgery procedure were randomized to receive pre-operatively and 24 h afterwards, orally either dexamethasone 9 mg or placebo. For pain medication, paracetamol and oxycodone capsules for rescue medication were given. The study ended on the evening of the third post-opera...
Source: Acta Anaesthesiologica Scandinavica - October 9, 2009 Category: Anesthesiology Authors: K. MATTILA, V. K. KONTINEN, E. KALSO, M. J. HYNYNEN Source Type: journals

The potential for μ-opioid receptor agonists to be anti-emetic in humans: a review of clinical dataemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In animal models of vomiting, [mu]-opioid (MOP, OP3) receptors mediate both emesis and anti-emesis. [mu]-receptors within the blood[ndash]brain barrier, mediating anti-emesis, are more rapidly accessible to lipid-soluble [mu]-opioid receptor agonists such as fentanyl than to morphine, and fentanyl has broad-spectrum anti-emetic effects in a number of species. Whether a similar situation exists in humans is not known. A search was performed for clinical studies comparing the emetic side effects of opioids administered peri-operatively in an attempt to identify differences between morphine and more lipid-soluble [mu]-recepto...
Source: Acta Anaesthesiologica Scandinavica - October 9, 2009 Category: Anesthesiology Authors: KEVIN D. JOHNSTON Source Type: journals

Triage and mortality in 2875 consecutive trauma patientsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Most studies on trauma and trauma systems have been conducted in the United States. We aimed to describe the factors predicting mortality in European trauma patients, with focus on triage. We prospectively registered all trauma patients in Eastern Denmark over 12 consecutive months. We analysed the flow of trauma patients through the system, the time spent at different locations, and we assessed the risk factors of mortality. We included 2875 trauma patients, of whom 158 (5.5%) died before arrival at the hospital. Most patients (75.3%) were brought to local hospitals and patients primarily (n=82) or secondarily triaged (n=...
Source: Acta Anaesthesiologica Scandinavica - October 9, 2009 Category: Anesthesiology Authors: R. MEISLER, A. B. THOMSEN, H. ABILDSTRØM, N. GULDSTAD, P. BORGE, S. W. RASMUSSEN, L. S. RASMUSSEN Source Type: journals

Knowledge Boosts Pain Killing Drugsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Giving cancer patients information on how to deal with their pain and manage their medicine can result in a 20 per cent improvement in pain control, according to research presented at the NCRI Cancer Conference in Birmingham.
Source: Pain / Anesthetics News From Medical News Today - October 9, 2009 Category: Anesthesiology Tags: Cancer / Oncology Source Type: news

Nicotinic acetylcholine receptor agonism: Progress in the management of neuropathic pain?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In this issue of PAIN, Rowbotham and co-workers present interesting results of a trial of the neuronal nicotinic acetylcholine receptor (NNR) agonist ABT-594 in patients with diabetic peripheral neuropathic pain . ABT-594 produced a statistically significant relief of pain compared to placebo, which supports the preclinical observations that NNR agonism resulting in opening of cationic channels is a relevant target in peripheral neuropathic pain. ABT-594 development followed upon proof of involvement of the α4β2 NNR subtype in pain processing. Thus, ABT-594 was specifically developed to target this receptor subtype to pr...
Source: Pain - October 9, 2009 Category: Anesthesiology Authors: Søren H. Sindrup Tags: Commentaries Source Type: journals

Spinal muscular atrophy: the challenges of 'doing the right thing'.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
PMID: 19807884 [PubMed - in process]
Source: Paediatric Anaesthesia - October 8, 2009 Category: Anesthesiology Authors: Wilton NC Tags: Paediatr Anaesth Source Type: journals

Impact of normal saline infusion on postoperative metabolic acidosis.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSIONS: Implementing serial Cl(eff) assessment could improve postoperative management by disclosing or excluding hyperchloremia as a cause of acidosis undetectable from SBE alone. Calculating the chloride-driven acidifying side effect of NS infusion using Cl(eff) improves the interpretation of SBE values and can optimize fluid management in postoperative metabolic acidosis. PMID: 19807885 [PubMed - in process]
Source: Paediatric Anaesthesia - October 8, 2009 Category: Anesthesiology Authors: Mann C, Held U, Herzog S, Baenziger O Tags: Paediatr Anaesth Source Type: journals

Parent-assisted or nurse-assisted epidural analgesia: is this feasible in pediatric patients?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSIONS: Parent-assisted or nurse-assisted epidural analgesia can be safely administered to children undergoing surgery who are physically or cognitively unable or unwilling to self-activate a demand dose. Additional studies are needed to compare the efficacy of PNEA with other modalities for postoperative pain control in children. PMID: 19807886 [PubMed - in process]
Source: Paediatric Anaesthesia - October 8, 2009 Category: Anesthesiology Authors: Birmingham PK, Suresh S, Ambrosy A, Porfyris S Tags: Paediatr Anaesth Source Type: journals

Epinephrine test dose in children: is it interpretable on ECG monitor?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSION: An increase in T-wave amplitude can easily be detected by carefully observing the ECG monitor or an ECG printout within a minute following the accidental i.v. administration of 0.1 ml x kg(-1) of 1% lidocaine-epinephrine (0.5 microg x kg(-1)) regional anesthetic test dose in children under sevoflurane anesthesia. PMID: 19807887 [PubMed - in process]
Source: Paediatric Anaesthesia - October 8, 2009 Category: Anesthesiology Authors: Varghese E, Deepak KM, Chowdary KV Tags: Paediatr Anaesth Source Type: journals

Anesthesia in Brown-Vialetto-Van Laere syndrome.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
PMID: 19807888 [PubMed - in process]
Source: Paediatric Anaesthesia - October 8, 2009 Category: Anesthesiology Authors: Fell D Tags: Paediatr Anaesth Source Type: journals

Fibreoptic intubation through the LMA in children.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
PMID: 19807889 [PubMed - in process]
Source: Paediatric Anaesthesia - October 8, 2009 Category: Anesthesiology Authors: Mayhew J Tags: Paediatr Anaesth Source Type: journals

Laryngeal mask airway-aided fiberoptic tracheal intubation in infant--a modified technique.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
PMID: 19807890 [PubMed - in process]
Source: Paediatric Anaesthesia - October 8, 2009 Category: Anesthesiology Authors: Khan RM, Sharma PK, Kaul N Tags: Paediatr Anaesth Source Type: journals

Use of an adult fiberoptic bronchoscope to facilitate endotracheal intubation in children with difficult airways.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
PMID: 19807891 [PubMed - in process]
Source: Paediatric Anaesthesia - October 8, 2009 Category: Anesthesiology Authors: Xue FS, Liu JH, Zhang YM, Liao X Tags: Paediatr Anaesth Source Type: journals

Use of the Glidescope video laryngoscope.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
PMID: 19807892 [PubMed - in process]
Source: Paediatric Anaesthesia - October 8, 2009 Category: Anesthesiology Authors: Gooden CK Tags: Paediatr Anaesth Source Type: journals

Use of an extraoral method to fix endotracheal tube during craniomaxillofacial surgery.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
PMID: 19807893 [PubMed - in process]
Source: Paediatric Anaesthesia - October 8, 2009 Category: Anesthesiology Authors: Xue FS, Xu YC, Liao X, Zhang YM Tags: Paediatr Anaesth Source Type: journals

Epidural catheter occlusion: disease-related or technique-related?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
PMID: 19807894 [PubMed - in process]
Source: Paediatric Anaesthesia - October 8, 2009 Category: Anesthesiology Authors: Veyckemans F, Scholtes JL Tags: Paediatr Anaesth Source Type: journals

Ganglion impar block for management of chronic coccydynia in an adolescent.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
PMID: 19807895 [PubMed - in process]
Source: Paediatric Anaesthesia - October 8, 2009 Category: Anesthesiology Authors: Ellinas H, Sethna NF Tags: Paediatr Anaesth Source Type: journals

Gas flow in the upper airway: turbulent or laminar?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Source: Pediatric Anesthesia - October 8, 2009 Category: Anesthesiology Authors: Jerrold Lerman Source Type: journals

Variable pre-transfusion patient identification practices exist in the perioperative setting.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSION: Due to intraoperative inacessibility, the system of patient ID banding has inherent limitations as a means for providing consistent pre-transfusion checks in surgical patients. A consistently accessible ID source that is continuously affixed to surgical patients should be introduced in the OR. PMID: 19816751 [PubMed - as supplied by publisher]
Source: Canadian Journal of Anaesthesia - October 8, 2009 Category: Anesthesiology Authors: Burrows JM, Callum JL, Belo S, Etchells E, Leeksma A Tags: Can J Anaesth Source Type: journals

[Peripheral nerve blocks of the lower extremities : Clinical and practical aspects.]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Peripheral nerve blocks (PNBs) of the lower extremities are effective techniques for anesthesia and postoperative pain control. So far, these techniques have been used less frequently than PNBs of the upper limb. Nevertheless, growing awareness of complications of neuroaxial techniques, improved equipment and modern techniques for nerve localization have led to an increased use of PNBs of the lower limb. Anesthesiologists should be familiar with the anatomical basics and procedural details of these PNBs. They should also know the typical complications and side-effects and thoroughly inform patients about such potential...
Source: Der Anaesthesist - October 8, 2009 Category: Anesthesiology Authors: Reske AW, Reske AP, Meier V, Wiegel M Tags: Anaesthesist Source Type: journals

[Respiratory depression after an accidental large dose of intrathecal sufentanil.]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
PMID: 19819663 [PubMed - as supplied by publisher]
Source: Annales Francaises d'Anesthesie et de Reanimation - October 8, 2009 Category: Anesthesiology Authors: Bourgeade F, Payen M, Daigremont C, Malinovsky JM Tags: Ann Fr Anesth Reanim Source Type: journals

[Medication error in anaesthesia practice: Multimodal prevention and individual control.]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
PMID: 19819662 [PubMed - as supplied by publisher]
Source: Annales Francaises d'Anesthesie et de Reanimation - October 8, 2009 Category: Anesthesiology Authors: Benhamou D, Auroy Y, Amalberti R Tags: Ann Fr Anesth Reanim Source Type: journals

Statistical Modeling of Average and Variability of Time to Extubation for Meta-Analysis Comparing Desflurane to Sevoflurane.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: Desflurane reduces the average extubation time and the variability of extubation time by 20%-25% relative to sevoflurane. The principal economic value of these end points is their reductions of direct (labor) costs of OR time. However, reductions in intangible costs of prolonged extubation are real, being associated with subsequent delays. Reductions in the average and variance of times to extubation can be interpreted and monitored in terms of corresponding expected 75% reductions in the incidences of prolonged extubation times by using desflurane relative to sevoflurane. PMID: 19820242 [PubMed - as supplied by publisher]
Source: Anesthesia and Analgesia - October 8, 2009 Category: Anesthesiology Authors: Dexter F, Bayman EO, Epstein RH Tags: Anesth Analg Source Type: journals

An Evaluation of Remifentanil-Sevoflurane Response Surface Models in Patients Emerging from Anesthesia: Model Improvement Using Effect-Site Sevoflurane Concentrations.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Discussion: Results confirmed, in part, our study hypothesis; accounting for the lag time between Ce and ET sevoflurane concentrations improved model predictions of responsiveness but had no effect on predicting a response to a noxious stimulus in the recovery room. These models may be useful in predicting events of clinical interest but large-scale evaluations with numerous patients are needed to better characterize model performance. PMID: 19820241 [PubMed - as supplied by publisher]
Source: Anesthesia and Analgesia - October 8, 2009 Category: Anesthesiology Authors: Johnson KB, Syroid ND, Gupta DK, Manyam SC, Pace NL, Lapierre CD, Egan TD, White JL, Tyler D, Westenskow DR Tags: Anesth Analg Source Type: journals

Inhaled Anesthetic Potency in Aged Alzheimer Mice.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: These results show that the genetic vulnerabilities and neuropathology associated with AD produce a small but significant decrease in sensitivity to the hypnotic actions of three inhaled anesthetics. Emergence times were not altered. PMID: 19820240 [PubMed - as supplied by publisher]
Source: Anesthesia and Analgesia - October 8, 2009 Category: Anesthesiology Authors: Bianchi SL, Caltagarone BM, Laferla FM, Eckenhoff RG, Kelz MB Tags: Anesth Analg Source Type: journals

Response Surface Model Predictions of Emergence and Response to Pain in the Recovery Room: An Evaluation of Patients Emerging from an Isoflurane and Fentanyl Anesthetic.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This study explored the feasibility of adapting the predictions of sevoflurane-remifentanil interaction models to an isoflurane-fentanyl anesthetic. We hypothesized that model predictions adapted for isoflurane and fentanyl are consistent with observed patient responses and are similar to the predictions observed in our previous work with sevoflurane-remifentanil/fentanyl anesthetics. Methods: Twenty-five patients scheduled for elective surgery received a fentanyl-isoflurane anesthetic. Model predictions of unresponsiveness were recorded at emergence, and predictions of a response to noxious stimulus were recorded when pat...
Source: Anesthesia and Analgesia - October 8, 2009 Category: Anesthesiology Authors: Syroid ND, Johnson KB, Pace NL, Westenskow DR, Tyler D, Brühschwein F, Albert RW, Roalstad S, Costy-Bennett S, Egan TD Tags: Anesth Analg Source Type: journals

Practice Misalignments in Randomized Controlled Trials: Identification, Impact, and Potential Solutions.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In this study, we review three recent RCTs to demonstrate how practice misalignments can affect the safety, results, and conclusions of RCTs. Furthermore, we discuss methods to prospectively identify potentially important relationships between therapy titration and patient- and disease-specific characteristics. Finally, we review trial design options that may minimize the occurrence and impact of practice misalignments. Because these designs may limit the feasibility of a clinical trial, a thorough characterization of usual care is necessary to determine whether one of these designs should be used to protect patient safety...
Source: Anesthesia and Analgesia - October 8, 2009 Category: Anesthesiology Authors: Deans KJ, Minneci PC, Danner RL, Eichacker PQ, Natanson C Tags: Anesth Analg Source Type: journals

Transgenic Alzheimer Mice Have a Larger Minimum Alveolar Anesthetic Concentration of Isoflurane than Their Nontransgenic Littermates.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: The increased MAC value in aged heterozygote APP23 mice seems to be attributable to changes related to Alzheimer's disease. PMID: 19820237 [PubMed - as supplied by publisher]
Source: Anesthesia and Analgesia - October 8, 2009 Category: Anesthesiology Authors: Eckel B, Richtsfeld M, Starker L, Blobner M Tags: Anesth Analg Source Type: journals

Postoperative Activity, but Not Preoperative Activity, of Antithrombin Is Associated with Major Adverse Cardiac Events After Coronary Artery Bypass Graft Surgery.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: Preoperative AT activity is not associated with MACE after CABG surgery. MACE is independently associated with postoperative AT activity but only at time points occurring predominantly after the MACE. PMID: 19820236 [PubMed - as supplied by publisher]
Source: Anesthesia and Analgesia - October 8, 2009 Category: Anesthesiology Authors: Garvin S, Muehlschlegel JD, Perry TE, Chen J, Liu KY, Fox AA, Collard CD, Aranki SF, Shernan SK, Body SC Tags: Anesth Analg Source Type: journals

Anesthesia and the Old Brain.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The perioperative period may have long-term consequences on cognitive function in the elderly patient. In this special article, we summarize the rationale and evidence that the anesthetic per se is a contributor. The evidence at this point is considered suggestive and further research is needed, especially in humans. PMID: 19820235 [PubMed - as supplied by publisher]
Source: Anesthesia and Analgesia - October 8, 2009 Category: Anesthesiology Authors: Tang J, Eckenhoff MF, Eckenhoff RG Tags: Anesth Analg Source Type: journals

Automation Is No Substitute For Accuracy In Nerve Conduction Studiesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
To the patient, automated nerve conduction studies (NCSs) may sound appealing because they are less invasive than needle electromyography (EMG). To the physician with no formal electrodiagnostic (EDX) training, the ability to perform an automated test in their office is convenient for patients and may generate additional revenue for their practice.
Source: Pain / Anesthetics News From Medical News Today - October 8, 2009 Category: Anesthesiology Tags: Neurology / Neuroscience Source Type: news

diflunisal, Dolobidemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Title: diflunisal, DolobidCategory: MedicationsCreated: 12/31/1997Last Editorial Review: 10/8/2009
Source: MedicineNet Chronic Pain General - October 8, 2009 Category: Anesthesiology Source Type: consumer

choline magnesium salicylate, Trilisateemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Title: choline magnesium salicylate, TrilisateCategory: MedicationsCreated: 12/31/1997Last Editorial Review: 10/8/2009
Source: MedicineNet Chronic Pain General - October 8, 2009 Category: Anesthesiology Source Type: consumer

Sebelius Urges Americans to Get Swine Flu Vaccineemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Title: Sebelius Urges Americans to Get Swine Flu VaccineCategory: Health NewsCreated: 10/7/2009 12:10:00 PMLast Editorial Review: 10/8/2009
Source: MedicineNet Chronic Pain General - October 8, 2009 Category: Anesthesiology Source Type: consumer

2nd Knee Surgery Common Among Young Patientsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Title: 2nd Knee Surgery Common Among Young PatientsCategory: Health NewsCreated: 10/7/2009 4:10:00 PMLast Editorial Review: 10/8/2009
Source: MedicineNet Chronic Pain General - October 8, 2009 Category: Anesthesiology Source Type: consumer

Reducing bias in outcome measuresemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Source: Pediatric Anesthesia - October 7, 2009 Category: Anesthesiology Authors: Jerrold Lerman Source Type: journals