Anesthesiology
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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 17.
Congenital tracheal stenosis managed with external chest compression exhalation technique for acute airway obstruction relief.
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PMID: 19754494 [PubMed - in process]
Source: Paediatric Anaesthesia - September 18, 2009 Category: Anesthesiology Authors: Al-Alami AA, Strricker L, Ahmed Z, Rajan S, Jwaida B, Zestos M Tags: Paediatr Anaesth Source Type: journals
Successful intubation using a simple fiberoptic assisted laryngoscope for Treacher Collins syndrome.
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We present three cases of Treacher Collins syndrome whose tracheas were successfully intubated with the aid of the FLS. These cases suggest that the FLS may be a useful alternative in the case of difficult pediatric intubation.
PMID: 19754495 [PubMed - in process]
Source: Paediatric Anaesthesia - September 18, 2009 Category: Anesthesiology Authors: Sugawara Y, Inagawa G, Satoh K, Kikuchi T, Goto T Tags: Paediatr Anaesth Source Type: journals
Health Tip: Could It Be a Torn Rotator Cuff?
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Title: Health Tip: Could It Be a Torn Rotator Cuff?Category: Health NewsCreated: 9/18/2009 8:10:00 AMLast Editorial Review: 9/18/2009
Source: MedicineNet Chronic Pain General - September 18, 2009 Category: Anesthesiology Source Type: consumer
Numerical rating scale for self-report of pain intensity in children and adolescents: Recent progress and further questions
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Until very recently there has been an anomaly in the assessment of the intensity of pediatric pain. The most commonly used self-report scale is the one that, up to now, has had the smallest amount of supportive research. This scale, the numerical rating scale (NRS), is administered by asking patients to say a number, usually from 0 to 10, to express the intensity of their pain.
Source: European Journal of Pain - September 18, 2009 Category: Anesthesiology Authors: Carl L. von Baeyer Tags: Editorial Source Type: journals
Introduction
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Source: Seminars in Cardiothoracic and Vascular Anesthesia - September 17, 2009 Category: Anesthesiology Authors: Nuttall, G. A., Schears, G. J. Tags: Articles Source Type: journals
Update on Safety Equipment for Extracorporeal Life Support (ECLS) Circuits
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Though much has been surveyed and written about the equipment aspects of extracorporeal life support (ECLS) in the past 10 years, there is value in reviewing the use and nonuse of multiple safety devices and techniques. Minimally equipped ECLS circuits for adult and pediatric bridge to decision during cardiac and respiratory failure are rapidly gaining popularity to maintain simplicity and portability. ECLS circuits employed for long-term therapy are outfitted differently and should include more safety devices. The purpose of this review is to compare and contrast the spectrum of minimally equipped ECLS circuits to circuit...
Source: Seminars in Cardiothoracic and Vascular Anesthesia - September 17, 2009 Category: Anesthesiology Authors: Riley, J. B., Scott, P. D., Schears, G. J. Tags: Articles Source Type: journals
Optimal Time for Initiating Extracorporeal Membrane Oxygenation
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The technical evolution of extracorporeal membrane oxygenation (ECMO) coincides with the vast improvement in intensive care medicine of the past 4 decades. Extracorporeal circulatory technology substitutes for acutely failed cardiac or pulmonary function until these organs regain sustainable function through goal-oriented intensive care practice. The technology has been validated to improve survival in select patients who would otherwise have 100% mortality. This is by far the most complex life-sustaining technology employed and thus can contribute significant risks such that the decision to institute ECMO requires prompt ...
Source: Seminars in Cardiothoracic and Vascular Anesthesia - September 17, 2009 Category: Anesthesiology Authors: Haile, D. T., Schears, G. J. Tags: Articles Source Type: journals
Anticoagulation and Coagulation Management for ECMO
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Advances in extracorporeal membrane oxygenation (ECMO) management have helped to reduce complications compared with its inception but they remain high. The principal causes of mortality and morbidity are bleeding and thrombosis. The nonbiologic surface of an extracorporeal circuit provokes a massive inflammatory response leading to consumption and activation of procoagulant and anticoagulant components. The vast differences in neonatal and adult anticoagulation and transfusion requirements demands tremendous clinical knowledge to provide the best care. Increased use of thrombelastogram will complement other methods current...
Source: Seminars in Cardiothoracic and Vascular Anesthesia - September 17, 2009 Category: Anesthesiology Authors: Oliver, W. C. Tags: Articles Source Type: journals
ECMO Cannulation Controversies and Complications
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Advances in extracorporeal life support have expanded indications for use extending beyond patients undergoing cardiac surgery. The approach to cannulation in patients requiring extracorporeal membrane oxygenation should be individualized and based on the specific clinical scenario in which the need arises. Adherence to proper techniques of vessel visualization, exposure, and cannulation along with accurate placement of cannulae will optimize flows and minimize complications in this setting. Patients in need of mechanical circulatory support require input from a multidisciplinary team approach with systematic clinical eval...
Source: Seminars in Cardiothoracic and Vascular Anesthesia - September 17, 2009 Category: Anesthesiology Authors: Stulak, J. M., Dearani, J. A., Burkhart, H. M., Barnes, R. D., Scott, P. D., Schears, G. J. Tags: Articles Source Type: journals
Extracorporeal Life Support: Utilization, Cost, Controversy, and Ethics of Trying to Save Lives
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Since the first successful application of extracorporeal membrane oxygenation (ECMO) in 1972, ECMO’s role in the management of respiratory and circulatory collapse continues to be refined and debated. Randomized clinical trials aimed at establishing efficacy and patient selection criteria have been fraught with ethical challenges. Growing concerns over rising health care costs require that careful evaluations of cost, utilization, and ethical issues surrounding heroic life-saving interventions such as ECMO are undertaken. Continued analyses of ECMO’s place in the medical management of respiratory and circulator...
Source: Seminars in Cardiothoracic and Vascular Anesthesia - September 17, 2009 Category: Anesthesiology Authors: Crow, S., Fischer, A. C., Schears, R. M. Tags: Articles Source Type: journals
Extracorporeal Membrane Oxygenation for the Treatment of Neonatal Respiratory Failure
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This review discusses the use of extracorporeal membrane oxygenation (ECMO) for the treatment of respiratory failure in neonates. After briefly reviewing the early history of neonatal ECMO, the authors describe the respiratory diagnoses most often treated with ECMO and the manner in which affected neonates are deemed to have "failed" conventional therapies and thus require ECMO. After reviewing the most common indications for ECMO, factors that influence the timing of conversion to extracorporeal life support, as well as criteria that may exclude patients from receiving ECMO therapy, are described. At the conclusion of thi...
Source: Seminars in Cardiothoracic and Vascular Anesthesia - September 17, 2009 Category: Anesthesiology Authors: Carey, W. A., Colby, C. E. Tags: Articles Source Type: journals
RCT of dietary intervention and quadriceps strengthening exercises on pain and function in overweight people with knee pain
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Source: BMJ
Area: News
The effect of dietary intervention or knee strengthening exercise, or both on knee pain and knee function in overweight and obese adults in the community has been assessed in a RCT. The study involved 389 men and women aged ?45 years with a BMI ? 28.0 and self reported knee pain from 5 general practices in Nottingham, who were randomised to one of the following interventions:
. Dietary intervention plus quadriceps strengthening exercises
. Dietary intervention alone
. Quadriceps strengthening exercises alone
. Advice leaflet only (control group)
Dietar...
Source: NeLM - Pain control - September 17, 2009 Category: Anesthesiology Source Type: organizations
[Experiment of an anesthetic adverse events reporting.]
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CONCLUSION: The reporting system is simple and available but some professionals don't declare, generating reporting bias. This network underlines major general dysfunctions (identity) but ways to solve are limited to date.
PMID: 19767172 [PubMed - as supplied by publisher]
Source: Annales Francaises d'Anesthesie et de Reanimation - September 17, 2009 Category: Anesthesiology Authors: Thevenin A, Chenet V, Schlumberger S, Fischler M Tags: Ann Fr Anesth Reanim Source Type: journals
[New oral anticoagulant agents: Do not walk out of the line.]
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PMID: 19767171 [PubMed - as supplied by publisher]
Source: Annales Francaises d'Anesthesie et de Reanimation - September 17, 2009 Category: Anesthesiology Authors: Samama CM, Rosencher N Tags: Ann Fr Anesth Reanim Source Type: journals
[Three cases of IgM monoclonal gammopathy with haemostasis dysfunction.]
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We relate three cases of IgM gammopathy with haemostatic dysfunction in the perioperative period. The acquired von Willebrand syndrome due to IgM gammopathy is rare and sometimes serious. Its different treatments and their efficiency are discussed: desmopressin, intravenous gammaglobulin, chemotherapy and plasmapheresis.
PMID: 19767170 [PubMed - as supplied by publisher]
Source: Annales Francaises d'Anesthesie et de Reanimation - September 17, 2009 Category: Anesthesiology Authors: Brémaud M, Giraud C, Boinot C, Caranobe C, Macchi L, Gohler C, Guilhot F Tags: Ann Fr Anesth Reanim Source Type: journals
[Antimicrobial prophylaxis for caesarean delivery: Before or after cord clamping? A meta-analysis.]
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CONCLUSION: This meta-analysis provides strong evidence that the preoperative rather than after cord clamping administration of antimicrobial prophylaxis for caesarean delivery provides a reduction in the incidence of endometritis and maternal total infectious morbidity without affecting the incidence of wound infection and neonatal infectious morbidity.
PMID: 19767169 [PubMed - as supplied by publisher]
Source: Annales Francaises d'Anesthesie et de Reanimation - September 17, 2009 Category: Anesthesiology Authors: Boselli E, Bouvet L, Rimmelé T, Chassard D, Allaouchiche B Tags: Ann Fr Anesth Reanim Source Type: journals
Health Tip: Stress Has Its Warning Signs
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Title: Health Tip: Stress Has Its Warning SignsCategory: Health NewsCreated: 9/17/2009 8:10:00 AMLast Editorial Review: 9/17/2009
Source: MedicineNet Chronic Pain General - September 17, 2009 Category: Anesthesiology Source Type: consumer
Propofol has anti-inflammatory effects on alveolar type II epithelial cells
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We investigated whether lipopolysaccharide (LPS) induced inflammation in alveolar epithelial type II (ATII) cells is through cluster of differentiation 14 (CD14) and Toll-like receptor 4 (TLR4) and the effect of different dosages of propofol on the inflammation in primary cultured rat ATII cells. Cultured ATII cells were randomly assigned to one of the following five groups: Group C: untreated group (control) cultured in the absence of propofol and LPS; Group LPS: treated with 1 [mu]g/ml LPS; Group P1: treated with 1 [mu]g/ml LPS and 25 [mu]M propofol; Group P2: treated with 1 [mu]g/ml LPS and 50 [mu]M propofol; Group P3: ...
Source: Acta Anaesthesiologica Scandinavica - September 16, 2009 Category: Anesthesiology Authors: L. MA, X. WU, W. CHEN, Y. FUJINO Source Type: journals
Sex differences in cerebral injury after severe haemorrhage and ventricular fibrillation in pigs
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Experimental studies of haemorrhagic shock have documented a superior haemodynamic response and a better outcome in female animals as compared with male controls. Such sexual dimorphism has, nevertheless, not been reported after circulatory arrest that follows exsanguination and shock. We aimed to study differences in cerebral injury markers after exsanguination cardiac arrest in pre-pubertal piglets. The hypothesis was that cerebral injury is less extensive in female animals, and that this difference is independent of sexual hormones or choice of resuscitative fluid. Thirty-two sexually immature piglets (14 males and 18 f...
Source: Acta Anaesthesiologica Scandinavica - September 16, 2009 Category: Anesthesiology Authors: E. SEMENAS, A. NOZARI, H. S. SHARMA, S. BASU, S. RUBERTSSON, L. WIKLUND Source Type: journals
Effects of surfactant replacement on alveolar overdistension and plasma cytokines in ventilator-induced lung injury
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Overdistension of the lung causes ventilator-induced lung injury (VILI) accompanied by surfactant abnormalities and inflammatory changes. We investigated the effects of surfactant replacement on overdistension of the terminal airspaces and plasma cytokine levels in VILI. VILI was induced by high-pressure ventilation (HPV) in rats anesthetized with pentobarbital, followed by ventilation for 2 h in the maintenance mode (tidal volume=10 ml/kg, positive end-expiratory pressure=7.5 cmH2O) with or without surfactant replacement. The sizes of the terminal airspaces were determined after fixing the lungs at an airway pressure of 1...
Source: Acta Anaesthesiologica Scandinavica - September 16, 2009 Category: Anesthesiology Authors: H. WU, T. KOBAYASHI, Q. WAN, W. SHI, H. QIAN, X. CUI, W. LI Source Type: journals
Pre-operative fasting: a nationwide survey of German anaesthesia departments
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Shorter pre-operative fasting improves clinical outcome without an increased risk. Since October 2004, German Anaesthesiology Societies have officially recommended a fast of 2 h for clear fluids and 6 h for solid food before elective surgery. We conducted a nationwide survey to evaluate the current clinical practice in Germany. Between July 2006 and January 2007, standardized questionnaires were mailed to 3751 Anaesthesiology Society members in leading positions requesting anonymous response. The overall response rate was 66% (n=2418). Of those, 2148 (92%) claimed familiarity with the new guidelines. About a third (n=806, ...
Source: Acta Anaesthesiologica Scandinavica - September 16, 2009 Category: Anesthesiology Authors: J.-P. BREUER, G. BOSSE, S. SEIFERT, L. PROCHNOW, J. MARTIN, A. SCHLEPPERS, G. GELDNER, E. SOREIDE, C. SPIES Source Type: journals
Dopamine increases renal oxygenation: a clinical study in post-cardiac surgery patients
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Imbalance of the renal medullary oxygen supply/demand relationship can cause ischaemic acute renal failure (ARF). The use of dopamine for prevention/treatment of ischaemic ARF has been questioned. It has been suggested that dopamine may increase renal oxygen consumption (RVO2) due to increased solute delivery to tubular cells, which may jeopardise renal oxygenation. Information on the effects of dopamine on renal perfusion, filtration and oxygenation in man is, however, lacking. We evaluated the effects of dopamine on renal blood flow (RBF), glomerular filtration rate (GFR), RVO2 and renal O2 demand/supply relationship, i....
Source: Acta Anaesthesiologica Scandinavica - September 16, 2009 Category: Anesthesiology Authors: BENGT REDFORS, GUDRUN BRAGADOTTIR, JOHAN SELLGREN, KRISTINA SWÄRD, SVEN-ERIK RICKSTEN Source Type: journals
Evaluation of the Video Intubation Unit in morbid obese patients
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Tracheal intubation may be more difficult in morbidly obese (MO) patients than in the non-obese. The aim of this study was to evaluate clinically if the use of the Video Intubation Unit (VIU), a video-optical intubation stylet, could improve the laryngoscopic view compared with the standard Macintosh laryngoscope in this specific population. We studied 40 MO patients (body mass index >35 kg/m2) scheduled for bariatric surgery. Each patient had a conventional laryngoscopy and a VIU inspection. The laryngoscopic grades (LG) using the Cormack and Lehane scoring system were noted and compared. Thereafter, the patients were ran...
Source: Acta Anaesthesiologica Scandinavica - September 16, 2009 Category: Anesthesiology Authors: I. BATHORY, J.-C. GRANGES, P. FRASCAROLO, L. MAGNUSSON Source Type: journals
Should dynamic parameters for prediction of fluid responsiveness be indexed to the tidal volume?
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The respiratory variation in the pre-ejection period ([Delta]PEP) has been used to predict fluid responsiveness in mechanically ventilated patients. Recently, we modified this parameter (PEPV) and showed that it was a reliable predictor for post-cardiac surgery, mainly paced, patients when moderately low tidal volumes were used. One of the modifications involved tidal volume indexation, which had not been proposed before for dynamic parameters. The aim of the present animal study was to investigate whether indexation to tidal volume should be part of a new definition of dynamic parameters such as the case for our newly pro...
Source: Acta Anaesthesiologica Scandinavica - September 16, 2009 Category: Anesthesiology Authors: S. T. VISTISEN, J. KOEFOED-NIELSEN, A. LARSSON Source Type: journals
Depth of anaesthesia and post-operative cognitive dysfunction
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A deep level of anaesthesia measured by the bispectral index has been found to improve processing speed as one aspect of cognitive function after surgery. The purpose of the present study was to assess the possible effect of the level of anaesthesia on post-operative cognitive dysfunction (POCD) 1 week after surgery, as assessed by a neuropsychological test battery. We included 70 patients >60 years of age scheduled for elective non-cardiac surgery with general anaesthesia. The depth of anaesthesia was monitored using the cerebral state monitor, which provided a cerebral state index (CSI) value. Cognitive function was asse...
Source: Acta Anaesthesiologica Scandinavica - September 16, 2009 Category: Anesthesiology Authors: J. STEINMETZ, K. S. FUNDER, B. T. DAHL, L. S. RASMUSSEN Source Type: journals
Regional anaesthesia for a Caesarean section in women with cardiac disease: a prospective study
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We conducted a prospective observational survey of pregnant women with cardiac disease. The aim was to analyse and present the mode of delivery, outcome, and haemodynamic changes during a caesarean section under regional anaesthesia in women with cardiac disease. All pregnant women with a cardiovascular diagnosis, except hypertension, were included in the registry. Based on the cardiac diagnoses, and on the New York Heart Association classification, a multidisciplinary group made recommendations for each patient and decided on the mode of delivery. The data from continuous, invasive haemodynamic monitoring in intermediate-...
Source: Acta Anaesthesiologica Scandinavica - September 16, 2009 Category: Anesthesiology Authors: E. LANGESÆTER, M. DRAGSUND, L. A. ROSSELAND Source Type: journals
Greater incidence of emergence agitation in children after sevoflurane anesthesia as compared with halothane: a meta-analysis of randomized controlled trials
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Source: DARE
Area: Evidence > Drug Class Focused Reviews
CRD Summary: This review assessed the incidence of emergence agitation in children anaesthetised with either sevoflurane or halothane. The authors concluded that sevoflurane exhibited a significantly greater incidence of emergence agitation. The authors' conclusions from this well-conducted review reflected the evidence presented and were likely to be reliable.
CRD Commentary: The review addressed a clear question and consulted a wide range of sources for studies with clear inclusion criteria. The literature search was restricted to publications in English and the...
Source: NeLM - Anaesthesia - September 16, 2009 Category: Anesthesiology Source Type: organizations
[What do we know about anesthetic mechanisms? : Hypnosis, unresponsiveness to surgical incision and amnesia.]
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This article focuses on presenting anesthetic sensitive ligand and voltage gated ion channels. The impact on anesthetic modulated ion channels is summarized for clinically commonly used anesthetics isoflurane, propofol and ketamine. Furthermore, the anesthetic features hypnosis, unresponsiveness to surgical incision and amnesia and their putative relevant anatomical sites in the central nervous system are briefly introduced.
PMID: 19760252 [PubMed - as supplied by publisher]
Source: Der Anaesthesist - September 16, 2009 Category: Anesthesiology Authors: Eckle VS, Hucklenbruch C, Todorovic SM Tags: Anaesthesist Source Type: journals
[Severe overdose in vitamin K antagonist secondary to grapefruit juice absorption.]
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We report here the case of a woman treated with VKA in whom massive absorption of grapefruit juice entailed an excessive VKA dosage and a severe haemorrhage.
PMID: 19766437 [PubMed - as supplied by publisher]
Source: Annales Francaises d'Anesthesie et de Reanimation - September 16, 2009 Category: Anesthesiology Authors: Desmard M, Hellmann R, Plantefève G, Mentec H Tags: Ann Fr Anesth Reanim Source Type: journals
Wideman and Sullivan Response to Letter to Editor by Vlaeyen et al.
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In their letter to the editor, Vlaeyen and his colleagues [The fear-avoidance model of pain: we are not there yet] raise several interesting points regarding our study and the related editorial by Nicholas . Their comments regarding our methodology and the evolution of the Fear-Avoidance (FA) model were greatly appreciated and will no doubt help direct future research.
Source: Pain - September 16, 2009 Category: Anesthesiology Authors: Timothy H. Wideman, Michael J.L. Sullivan Tags: Letters to the Editor Source Type: journals
Common Pain Cream Could Protect Heart During Attack
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New research from the University of Cincinnati (UC) shows that a common, over-the-counter pain salve rubbed on the skin during a heart attack could serve as a cardiac-protectant, preventing or reducing damage to the heart while interventions are administered. These findings are published in the Sept. 14 edition of the journal Circulation.
Source: Pain / Anesthetics News From Medical News Today - September 16, 2009 Category: Anesthesiology Tags: Cardiovascular / Cardiology Source Type: news
Shockwave Treatment May Not Be Best for Shoulder Pain
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Title: Shockwave Treatment May Not Be Best for Shoulder PainCategory: Health NewsCreated: 9/16/2009 9:52:00 AMLast Editorial Review: 9/16/2009
Source: MedicineNet Chronic Pain General - September 16, 2009 Category: Anesthesiology Source Type: consumer
[Neuroablative procedures in pain therapy.]
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Although surgical ablative procedures can be effective in the management of chronic pain of malignant and non-malignant origin, they are often disregarded as treatment options due to the fact that in the past these procedures were associated with high complication rates. The complications include the development of new neurological deficits and in cases of long-term follow-up, the occurrence of the old or new pain syndromes by deafferentation. On the other hand there exist many less invasive, e.g. neuromodulatory procedures or non-invasive measures (systemic oral or transdermal opioids) which are able to considerably r...
Source: Schmerz - September 15, 2009 Category: Anesthesiology Authors: Tronnier VM, Rasche D Tags: Schmerz Source Type: journals
Not All Kids With Head Injuries Need Brain Scans
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Title: Not All Kids With Head Injuries Need Brain ScansCategory: Health NewsCreated: 9/14/2009 6:10:00 PMLast Editorial Review: 9/15/2009
Source: MedicineNet Chronic Pain General - September 15, 2009 Category: Anesthesiology Source Type: consumer
Health Tip: Protect Your Eyes
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Title: Health Tip: Protect Your EyesCategory: Health NewsCreated: 9/15/2009 8:10:00 AMLast Editorial Review: 9/15/2009
Source: MedicineNet Chronic Pain General - September 15, 2009 Category: Anesthesiology Source Type: consumer
Ultrastructural Changes in Axons Following Exposure to Pulsed Radiofrequency Fields
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In this study, PRF is applied to the afferent axons of the sciatic nerves of rats. A standard radiofrequency (RF) electrode and RF generator is used to apply the RF signal output to the sciatic nerve using standard PRF parameters that have been successfully used in clinical practice. The ultrastructure of the treated axons is observed after 10 days by electron microscopy. A control, sham application is simultaneously applied to the contralateral sciatic nerve to provide a statistical differential comparison. It is found that the internal ultrastructural components of the axons show microscopic damage after PRF exposure, in...
Source: Pain Practice - September 14, 2009 Category: Anesthesiology Authors: Serdar Erdine, Ayhan Bilir, Eric R. Cosman, Eric R. Cosman Jr. Source Type: journals
The Vertebral Artery is Unlikely to be the Sole Source of Vascular Complications Occurring during Stellate Ganglion Block
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Discussion: Arterial vessels other than the vertebral artery that also supply the anterior spinal cord and brain stem pass directly anterior to the transverse processes at the most common sites of the SGB. It is anatomically possible, therefore, that accidental injection or induced spasm of these vessels and not the vertebral arteries is responsible for some cases of seizure, hematoma, or other vascular complications during SGB.
Source: Pain Practice - September 14, 2009 Category: Anesthesiology Authors: Marc A. Huntoon Source Type: journals
Anesthesia for children with hyperleukocytosis a retrospective review
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Conclusion: Children with leukemia-related hyperleukocytosis often require general anesthesia at the time of presentation and are at significant perioperative risk. Respiratory adverse events are very common and mandate close postanesthesia care.
Source: Pediatric Anesthesia - September 14, 2009 Category: Anesthesiology Authors: CLEMENT FONG, WINNIE FUNG, JANE McDONALD, LUCE DALLA-POZZA, JONATHAN DE LIMA Source Type: journals
Broken Finger
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Title: Broken FingerCategory: Diseases and ConditionsCreated: 9/14/2009 1:40:00 PMLast Editorial Review: 9/14/2009 1:40:51 PM
Source: MedicineNet Chronic Pain General - September 14, 2009 Category: Anesthesiology Source Type: consumer
Perisurgical amitriptyline produces a preventive effect on afferent hypersensitivity following spared nerve injury
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This study indicates that tricyclic antidepressants given in the perioperative period may be useful in preventing nerve injury-induced sensory changes that contribute to the development of chronic post-surgical neuropathic pain.
Source: Pain - September 14, 2009 Category: Anesthesiology Authors: Andre Arsenault, Jana Sawynok Tags: Research papers Source Type: journals
Conference report: Study compares fentanyl nasal spray (Instanyl®) to oral transmucosal fentanyl (Actiq®) in breakthrough cancer pain
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Source: EurekAlert
Area: News
Findings from an open-label crossover trial comparing intranasal fentanyl spray (Instanyl®) and oral transmucosal fentanyl citrate (OTFC; Actiq®) for the treatment of breakthrough pain in patients with cancer have been presented at the 6th congress of the European Federation of Chapters of the International Association for the Study of Pain, and are summarised in a press release (See link below).
Only brief details of trial design, methodology and results are available. The trial was multinational and compared the efficacy of the two treatments in patients who were receivin...
Source: NeLM - Pain control - September 13, 2009 Category: Anesthesiology Source Type: organizations
Anesthetic-induced neurotoxicity of the neonate: time for clinical guidelines?
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Source: Pediatric Anesthesia - September 13, 2009 Category: Anesthesiology Authors: ROBERT D. SANDERS, ANDREW DAVIDSON Source Type: journals
Role of SIP30 in the development and maintenance of peripheral nerve injury-induced neuropathic pain
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Abstract: Using the chronic constriction injury (CCI) model of neuropathic pain, we profiled gene expression in the rat spinal cord, and identified SIP30 as a gene whose expression was elevated after CCI. SIP30 was previously shown to interact with SNAP25, but whose function was otherwise unknown. We now show that in the spinal cord, SIP30 was present in the dorsal horn laminae where the peripheral nociceptive inputs first synapse, co-localizing with nociception-related neuropeptides CGRP and substance P. With the onset of neuropathic pain after CCI surgery, SIP30 mRNA and protein levels increased in the ipsilateral side o...
Source: Pain - September 13, 2009 Category: Anesthesiology Authors: Yu-Qiu Zhang, Ning Guo, Guangdun Peng, Mei Han, Jeremy Raincrow, Chi-hua Chiu, Lique M. Coolen, Robert J. Wenthold, Zhi-Qi Zhao, Naihe Jing, Lei Yu Tags: Research papers Source Type: journals
Instanyl (fentanyl) 50, 100 and 200 mcg/dose nasal spray - New product
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Source: eMC (electronic Medicines Compendium)
Area: Other Library Updates > SPC Changes
Instanyl is a new product indicated for the management of breakthrough pain in adults already receiving maintenance opioid therapy for chronic cancer pain. Breakthrough pain is a transitory exacerbation of pain that occurs on a background of otherwise controlled persistent pain.
Patients receiving maintenance opioid therapy are those who are taking at least 60 mg of oral morphine daily, at least 25 micrograms of transdermal fentanyl per hour, at least 30 mg oxycodone daily, at least 8 mg of oral hydromorphone daily or an equianalgesi...
Source: NeLM - Pain control - September 12, 2009 Category: Anesthesiology Source Type: organizations
[How many patient deaths can a team cope with? : A nationwide survey of palliative care units in Germany.]
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CONCLUSION: A clearer definition of the objectives of palliative care and support of team communication are desirable.
PMID: 19756766 [PubMed - as supplied by publisher]
Source: Schmerz - September 11, 2009 Category: Anesthesiology Authors: Müller M, Pfister D, Markett S, Jaspers B Tags: Schmerz Source Type: journals
Juvenile Bone Health
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Title: Juvenile Bone HealthCategory: Diseases and ConditionsCreated: 9/11/2009 4:25:00 PMLast Editorial Review: 9/11/2009 4:25:16 PM
Source: MedicineNet Chronic Pain General - September 11, 2009 Category: Anesthesiology Source Type: consumer
Black Eye
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Title: Black EyeCategory: Diseases and ConditionsCreated: 9/11/2009 11:44:00 AMLast Editorial Review: 9/11/2009 11:44:17 AM
Source: MedicineNet Chronic Pain General - September 11, 2009 Category: Anesthesiology Source Type: consumer
aurothioglucose, Solganal
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Title: aurothioglucose, SolganalCategory: MedicationsCreated: 12/31/1997Last Editorial Review: 9/11/2009
Source: MedicineNet Chronic Pain General - September 11, 2009 Category: Anesthesiology Source Type: consumer
Girl in Iconic Vietnam War Photo Brings Message of Hope
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Title: Girl in Iconic Vietnam War Photo Brings Message of HopeCategory: Health NewsCreated: 9/10/2009 8:10:00 AMLast Editorial Review: 9/11/2009
Source: MedicineNet Chronic Pain General - September 11, 2009 Category: Anesthesiology Source Type: consumer
In the October 2009 BJA ...
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Source: British Journal of Anaesthesia - September 10, 2009 Category: Anesthesiology Tags: In This Issue Source Type: journals
