Anesthesiology
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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 19.
Some Parents Aren't Giving Kids Pain Meds Post-Surgery
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Title: Some Parents Aren't Giving Kids Pain Meds Post-SurgeryCategory: Health NewsCreated: 9/9/2009 12:10:00 PMLast Editorial Review: 9/10/2009
Source: MedicineNet Chronic Pain General - September 10, 2009 Category: Anesthesiology Source Type: consumer
Blood-Stained Combat Boots and Acute Pain Medicine
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Source: Pain Medicine - September 9, 2009 Category: Anesthesiology Authors: Chester"Trip" Buckenmaier III Source Type: journals
Targinact (oxycodone / naloxone) 5mg/2.5mg and 40mg/20mg prolonged release tablets - New Product
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Source: Manufacturer notification
Area: Other Library Updates > SPC Changes
Targinact 5mg/2.5mg and 40mg/20mg prolonged release tablets are new strengths of this product launched by Napp.
These new strengths will add to the existing range of Targinact prolonged release tablets which are currently available in 10 mg/5 mg and 20 mg/10 mg tablet strengths. Targinact 5 mg/2.5 mg prolonged release tablets are intended for dose titration when initiating opioid therapy and individual dose adjustment.
Targinact is indicated for severe pain, which can be adequately managed only with opioid analgesics.
The opioid antagon...
Source: NeLM - Pain control - September 9, 2009 Category: Anesthesiology Source Type: organizations
Evaluating outcomes in ultrasound-guided regional anesthesia.
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PMID: 19763732 [PubMed - as supplied by publisher]
Source: Canadian Journal of Anaesthesia - September 9, 2009 Category: Anesthesiology Authors: Chin KJ, Chan V Tags: Can J Anaesth Source Type: journals
Airway topicalization during tracheal intubation using the Airtraq((R)) laryngoscope in anesthetized patients.
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PMID: 19763731 [PubMed - as supplied by publisher]
Source: Canadian Journal of Anaesthesia - September 9, 2009 Category: Anesthesiology Authors: Xue FS, He N, Liu JH, Liao X Tags: Can J Anaesth Source Type: journals
Dexmedetomidine supplemented with local anesthesia for awake laryngoplasty
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Abstract: Certain laryngeal procedures require a sedated patient who is responsive to allow for the assessment of vocalization. Dexmedetomidine as a single agent for sedation and anxiolysis for awake laryngoplasty in a patient with unilateral vocal fold paralysis is presented.
Source: Journal of Clinical Anesthesia - September 9, 2009 Category: Anesthesiology Authors: Basem Abdelmalak, Larina Gutenberg, Robert R. Lorenz, Michael Smith, Ehab Farag, D. John Doyle Tags: Case Reports Source Type: journals
Acid–base disturbances: A need to reunify clinical and scientific medicine
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Disturbances of acid–base homeostasis are a well recognised and clinically significant element of acute illness and physiological derangements. Over many decades, there have been high profile changes in perspectives of the interpretation, clinical effects, diagnostic significance and management of such metabolic alterations. One of the side-effects of these challenges has been to place a shroud of confusion over many aspects of understanding in acid–base physiology, and this decade is no different from others in adding further to this state. More importantly perhaps, is that the more the academic arguments reign over t...
Source: Current Anaesthesia and Critical Care - September 9, 2009 Category: Anesthesiology Authors: J.M. Handy Tags: Letters to the Editor Source Type: journals
Eclampsia a rare complication: A reminder that magnesium sulphate saves lives
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Posterior Reversible Encephalopathy Syndrome (PRES) in a patient of eclampsia with ‘partial’ HELLP-syndrome presenting with status-epilepticus The case highlights a rare but interesting condition; posterior reversible encephalopathy syndrome (PRES) a clinicoradiological syndrome associated with hypertensive disorders, which has only been recognised since 1996. There have been several other obstetric cases of PRES reported, all of which seem to have a similarly good neurological outcome.
Source: Current Anaesthesia and Critical Care - September 9, 2009 Category: Anesthesiology Authors: Jackie Durbridge Tags: Letters to the Editor Source Type: journals
Sodium bicarbonate—the bicarbonate challenge test in metabolic acidosis: A practical consideration
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This article explores the combination of a bicarbonate challenge test with defined endpoints of haemodynamic resuscitation as a semi-quantitative method for differentiating between simultaneous reasons for severe metabolic acidosis.
Source: Current Anaesthesia and Critical Care - September 9, 2009 Category: Anesthesiology Authors: Mark G.A. Palazzo Tags: Metabolic Source Type: journals
Therapeutic adjuncts in sepsis
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This is a very interesting and timely discussion of some controversial and not so controversial aspects of treatment adjuncts in sepsis. Critical care medicine is in a mild confusional state at present with surviving sepsis recommendations falling from grace and seemingly robust studies being unrepeatable or contradicted by further studies. None of the adjunct treatments described is the magic bullet but might they be sufficient to gain an edge in the treatment of this devastating and costly disease?
Source: Current Anaesthesia and Critical Care - September 9, 2009 Category: Anesthesiology Authors: Rick Keays Tags: Letters to the Editor Source Type: journals
Pain management: from basics to clinical practice
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Pain is fundamentally important to the human condition. It is the most common symptom experienced by patients in critical care and all those in the health care service should have a basic understanding of the mechanisms underlying pain and how best to treat patients in the clinical setting. Based on this basic understanding, it is thus essential to identify and understand the rational for pain relief and the strategies available. This excellent and timely publication brings together a collection of academics, clinical directors, consultants, specialist registrars and even a final year medical student, each contributing a c...
Source: Current Anaesthesia and Critical Care - September 9, 2009 Category: Anesthesiology Authors: Paul L. Chazot Tags: Focus on: Neuropathic Pain and Appraising Drug Safety Source Type: journals
Neuropathic pain and drug safety MCQs and self-assessment
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Source: Current Anaesthesia and Critical Care - September 9, 2009 Category: Anesthesiology Tags: Continuing Professional Development Source Type: journals
Case Scenario
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Source: Current Anaesthesia and Critical Care - September 9, 2009 Category: Anesthesiology Tags: Continuing Professional Development Source Type: journals
Focus on Glutamate Neuropharmacology
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The neuropharmacology focus in this double issue includes a number of reviews with a common thread, namely the glutamatergic system, including aspects of glutamate receptor regulation, molecular RNA editing and excitotoxicity, with therapeutic implications in Motor neuron disease, schizophrenia and clinical depression, a highly debilitating spectrum of diseases and disorders which affect, in the main, relatively young adults. Exciting new insights through basic research have provided new therapeutic targets and rationale strategies which are reviewed in this focus.
Source: Current Anaesthesia and Critical Care - September 9, 2009 Category: Anesthesiology Authors: Paul L. Chazot Tags: Focus on: Glutamate Neuropharmacology Source Type: journals
The role of AMPA receptor-mediated excitotoxicity in ALS: Is deficient RNA editing to blame?
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Summary: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by selective degeneration of upper and lower motor neurons. To date, glutamate modulator riluzole is the only drug that has proved effective against disease progression. Based on this evidence, it has been proposed that glutamate excitotoxicity contributes to the neurodegeneration observed in ALS, with α-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate receptors (AMPARs) emerging as a likely candidate for glutamate receptor-mediated excitotoxicity. The calcium (Ca2+) conductance of AMPARs is determined by the presence of the ed...
Source: Current Anaesthesia and Critical Care - September 9, 2009 Category: Anesthesiology Authors: Kathryn Duncan Tags: Focus on: Glutamate Neuropharmacology Source Type: journals
The current understanding of motor neuron disease
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Abstract: Motor Neuron Disease is a term defining a group of neurodegenerative diseases, in which motor neurons degenerate, leading to muscle wasting, paralysis and ultimately death. Here I review the current understanding of Amyotrophic Lateral Sclerosis (ALS), the most common form of MND, looking particularly at the causative factors, and the available treatments for the disease. Familial ALS can be caused by a mutation in SOD1; research into the effects of this mutation has given an insight into the mechanisms by which MND progresses. Mutant SOD1 causes the initiation and progression of MND via protein aggregation, disr...
Source: Current Anaesthesia and Critical Care - September 9, 2009 Category: Anesthesiology Authors: Emma Burvill Tags: Focus on: Glutamate Neuropharmacology Source Type: journals
The dopamine and glutamate theories of schizophrenia: A short review
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Abstract: Schizophrenia is a psychiatric disorder involving the impairment of normal thinking, emotion, and everyday behaviours. Characteristics of schizophrenia can be divided into positive, negative and cognitive symptoms. Contributory factors of the disorder include genetics, early environmental factors and neuropsychological factors. Many years of research has investigated the dopamine hypothesis and glutamate hypothesis of schizophrenia, but more recently the field is scrutinizing the combined interactions of the glutamatergic and dopaminergic systems.
Source: Current Anaesthesia and Critical Care - September 9, 2009 Category: Anesthesiology Authors: A. Bradford Tags: Focus on: Glutamate Neuropharmacology Source Type: journals
AMPA receptors: New targets for psychiatric disorders
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Summary: AMPA receptors are one of the major excitatory receptors within the CNS with many of their functional effects being mediated by alterations in their trafficking to the cell surface and targeting into the synapse. Integral to these functions, and consequently, AMPA receptor activity is a class of proteins termed transmembrane AMPA receptor regulatory proteins (TARPs) which also possess diverse effects on AMPA receptor pharmacology. Incredibly, despite the evident importance of TARPs in AMPA receptor function, very few studies even allude to the potential significance of their potential role within the glutamatergic...
Source: Current Anaesthesia and Critical Care - September 9, 2009 Category: Anesthesiology Authors: P.S. Donoghue Tags: Focus on: Glutamate Neuropharmacology Source Type: journals
Glycopeptide resistant enterococci: What's the problem?
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This article had the aim to give an overview on problems associated to the spread of GRE and to provide some recommendation about the management of infected or colonized patients.
Source: Current Anaesthesia and Critical Care - September 9, 2009 Category: Anesthesiology Authors: G. Birgand Tags: Infectious Disease Source Type: journals
Posterior reversible encephalopathy syndrome (PRES) in a patient of eclampsia with ‘partial’ HELLP syndrome presenting with status-epilepticus
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We report the management of a 21y-female with peripartum eclampsia and ‘partial’ HELLP syndrome (haemolysis, elevated liver enzymes and low-platelets) presenting with status-epilepticus. She had neurological, cardiovascular, hepatic, renal and hematological involvement along with electrolyte abnormalities. Early diagnosis along with timely supportive therapy resulted in the successful management of this challenging case. Recent understanding on the pathophysiology of this uncommon condition is discussed. We highlight the importance to obstetricians, intensive-care physicians and anesthesiologists of recognizing such cases.
Source: Current Anaesthesia and Critical Care - September 9, 2009 Category: Anesthesiology Authors: Harihar V. Hegde, Raghavendra P. Rao Tags: Obstetrics Source Type: journals
Adjunctive therapy of severe sepsis and septic shock in adults
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Summary: Sepsis continues to be a major unresolved medical challenge of the present. Despite earlier diagnosis and treatment initiation, source control, improvements in the standard of care and attempts at standardization of treatment and resuscitation protocols intensive care unit mortality rates for severe sepsis is 32.2% and 54.1% for septic shock. Further reduction in mortality may be achievable through knowledge and use of the expanding field of adjunctive therapy: a supplement to optimal, supportive, intensive therapy and antibiotic treatment.Numerous and unsuccessful trials targeted at inhibiting various essential i...
Source: Current Anaesthesia and Critical Care - September 9, 2009 Category: Anesthesiology Authors: T.H. Andersen, T.H. Jensen, L.W. Andersen Tags: Sepsis Source Type: journals
Editorial Board & Aims and Scope
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Source: Current Anaesthesia and Critical Care - September 9, 2009 Category: Anesthesiology Source Type: journals
Chronic issues: Intractable pain and appraising drug safety post-launch
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This issue of current anaesthesia and critical care covers two long standing problems in pharmacology: (i) how important it is to appraise drug safety objectively beyond clinical trials (using a combination of spontaneous and longitudinal reporting) and (ii) how difficult it is to treat patients in the chronic pain clinic effectively with currently available drugs. All of the contributing authors are experts in these fields in New Zealand.
Source: Current Anaesthesia and Critical Care - September 9, 2009 Category: Anesthesiology Authors: George Lees Tags: Focus on: Neuropathic Pain and Appraising Drug Safety Source Type: journals
Novel targets in pain research: The case for CB2 receptors as a biorational pain target
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Summary: The prevalence of neuropathic pain is rising, and is expected to further increase in aging populations. However, drug treatment for neuropathic pain remains inadequate, with the best available treatments having limited efficacy and dose-limiting side effects. Cannabinoids have been shown in clinical trials to be moderately effective at reducing neuropathic pain, but doses of cannabinoids currently in use are severely curtailed by psychoactive side effects through actions on the cannabinoid CB1 receptor. A relatively new class of drugs, selective cannabinoid CB2 receptor agonists, have shown considerable efficacy ...
Source: Current Anaesthesia and Critical Care - September 9, 2009 Category: Anesthesiology Authors: Philip W. Brownjohn, John C. Ashton Tags: Focus on: Neuropathic Pain and Appraising Drug Safety Source Type: journals
Voltage-gated sodium channels in nociception and their potential as targets for new drugs in treatment of chronic neuropathic pain
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Summary: Voltage-gated sodium channels are important in the pathophysiology of chronic neuropathic pain and as targets for analgesic drugs. This review will cover the molecular structure and signalling roles for this ion channel super-family with a focus on the channels thought to be involved in nociception. We highlight the mode of action of current analgesic drugs and the difficulty of treating chronic inflammatory or neuropathic pain states. The discovery of key channel classes, or familial mutations, associated with chronic pain syndromes has resulted in intensive drug discovery programmes. The quest for selective drug...
Source: Current Anaesthesia and Critical Care - September 9, 2009 Category: Anesthesiology Authors: George Lees, Edward Shipton Tags: Focus on: Neuropathic Pain and Appraising Drug Safety Source Type: journals
Complex regional pain syndrome – Mechanisms, diagnosis, and management
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This article explores an interdisciplinary setting with comprehensive approach (pharmacological, interventional, and psychological in conjunction with rehabilitation pathway) as the protocol for the practical management of CRPS. Insight in predisposing factors may facilitate early diagnosis and elucidate underlying mechanisms that could provide targets for pharmacotherapy.
Source: Current Anaesthesia and Critical Care - September 9, 2009 Category: Anesthesiology Authors: Edward A. Shipton Tags: Focus on: Neuropathic Pain and Appraising Drug Safety Source Type: journals
Appraising the post-marketing safety of medicines: A description of national and international pharmacovigilance with a focus on medicines used in chronic pain
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We describe the role of pharmacovigilance in detecting and evaluating emerging evidence of adverse drug reactions, i.e. “signals” using the New Zealand Pharmacovigilance Centre as an example. The benefits to individual patient safety through a medical warning system are of particular relevance to anaesthetic practice. Effective and holistic pharmacovigilance relies on voluntary reporting systems for all therapeutic products, prescription or cohort event monitoring of selected medicines and vaccines, and specific monitoring of medication error. Ongoing development of computational methods for data-mining in the voluntar...
Source: Current Anaesthesia and Critical Care - September 9, 2009 Category: Anesthesiology Authors: Ruth L. Savage, Desiree L. Kunac, Jeanette Johansson Tags: Focus on: Neuropathic Pain and Appraising Drug Safety Source Type: journals
Author Index to Volume 145
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Source: Pain - September 9, 2009 Category: Anesthesiology Source Type: journals
Subject Index to Volume 145
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Source: Pain - September 9, 2009 Category: Anesthesiology Source Type: journals
Contents to Volume 145
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Source: Pain - September 9, 2009 Category: Anesthesiology Source Type: journals
Editorial list
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Source: Pain - September 9, 2009 Category: Anesthesiology Source Type: journals
Instructions to authors
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Source: Pain - September 9, 2009 Category: Anesthesiology Source Type: journals
A practical guide to commonly performed ultrasound-guided peripheral-nerve blocks
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This article serves to display the most clinically relevant nerve blocks utilized in the perioperative setting. It is meant to be used as a clinical starting point for the development of regional anesthesia skills.
(C) 2009 Lippincott Williams & Wilkins, Inc.
Source: Current Opinion in Anaesthesiology - September 9, 2009 Category: Anesthesiology Tags: Pain medicine: Edited by Raymond Sinatra Source Type: journals
Cerebral autoregulation and anesthesia
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Purpose of review: This review will examine the recent literature on anesthesia and monitoring techniques in relation to cerebral autoregulation. We will discuss the effect of physiologic and pharmacological factors on cerebral autoregulation alongside its clinical relevance with the help of new evidence.
Recent findings: Intravenous anesthesia, such as combination of propofol and remifentanil, provides best preservation of autoregulation. Among inhaled agents sevoflurane appears to preserve autoregulation at all doses, whereas with other agents autoregulation is impaired in a dose-related manner.
Summary: Intraoperative c...
Source: Current Opinion in Anaesthesiology - September 9, 2009 Category: Anesthesiology Tags: Neuroanaesthesia: Edited by Arthur Lam Source Type: journals
milnacipran, Savella
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Title: milnacipran, SavellaCategory: MedicationsCreated: 9/9/2009 5:18:00 PMLast Editorial Review: 9/9/2009 5:18:33 PM
Source: MedicineNet Chronic Pain General - September 9, 2009 Category: Anesthesiology Source Type: consumer
Yoga Can Ease Lower Back Pain
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Title: Yoga Can Ease Lower Back PainCategory: Health NewsCreated: 9/8/2009 12:10:00 PMLast Editorial Review: 9/9/2009
Source: MedicineNet Chronic Pain General - September 9, 2009 Category: Anesthesiology Source Type: consumer
Review: Diagnosis and management of cervicogenic headache
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Source: Lancet Neurology
Area: News
The Lancet Neurology has featured a review on the diagnosis, and management of cervicogenic headache, which is characterised by pain referred to the head from the cervical spine.
Source: NeLM - Pain control - September 8, 2009 Category: Anesthesiology Source Type: organizations
Pharmacological Management of Persistent Pain in Older Persons
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Source: Pain Medicine - September 8, 2009 Category: Anesthesiology Source Type: journals
Evolving Pharmacological Management of Persistent Pain in Older Persons
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Source: Pain Medicine - September 8, 2009 Category: Anesthesiology Authors: Joseph T. Hanlon, Misha Backonja, Debra Weiner, Charles Argoff Source Type: journals
The Evolution of Pain Medicine: Residency Training for Health Care Reform
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Source: Pain Medicine - September 8, 2009 Category: Anesthesiology Authors: Rollin M. Gallagher Source Type: journals
Jayantilal Govind MB, ChB, DPH, MMed (Pain Med), FAFOM, FAFMM
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Source: Pain Medicine - September 8, 2009 Category: Anesthesiology Authors: Nikolai Bogduk Source Type: journals
Chronic Pain, Smoking, and Obesity: A Pain Physician's Perspective on Patient Selection
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Source: Pain Medicine - September 8, 2009 Category: Anesthesiology Authors: Gerald Aronoff Source Type: journals
2009 ANZCA ANNUAL SCIENTIFIC MEETING ABSTRACTS
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Source: Pain Medicine - September 8, 2009 Category: Anesthesiology Source Type: journals
Advanced Regional Anesthesia Morbidity and Mortality Grading System: Regional Anesthesia Outcomes Reporting (ROAR)
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Conclusions. The value of the ROAR system is that it identifies important issues in risk management in regional anesthesia, thereby providing opportunities for further investigation and clinical practice refinement. Furthermore, it provides for a common language when reporting outcomes in the regional anesthesia literature. Use of the ROAR system will provide consistency in outcomes reporting and facilitate comparisons between methods and procedures.
Source: Pain Medicine - September 8, 2009 Category: Anesthesiology Authors: Chester C. Buckenmaier III, Scott M. Croll, Cynthia H. Shields, Sean M. Shockey, Lisa L. Bleckner, Greg Malone, Anthony Plunkett, Geselle M. McKnight, Kyung H. Kwon, Richard Joltes, Alexander Stojadinovic Source Type: journals
Response to: Exercise Performance and Chronic Pain in Chronic Fatigue Syndrome: The Role of Pain Catastrophizing
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Source: Pain Medicine - September 8, 2009 Category: Anesthesiology Authors: Tom Kindlon Source Type: journals
Neurogenetics Can Help Turn Pain Concepts More Objective
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Source: Pain Medicine - September 8, 2009 Category: Anesthesiology Authors: Francisco Hélder Cavalcante Félix, Juvenia Bezerra Fontenele Source Type: journals
Pain, Exercise and Employment Status in Patients with Chronic Fatigue Syndrome: Research Priorities—Response to the Letter by T. Kindlon
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Source: Pain Medicine - September 8, 2009 Category: Anesthesiology Authors: Jo Nijs, Jessica Van Oosterwijck, Mira Meeus Source Type: journals
Re: Neurogenetics Can Help Turn Pain Concepts More Objective
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Source: Pain Medicine - September 8, 2009 Category: Anesthesiology Authors: Claudia M. Campbell, Robert R. Edwards Source Type: journals
Radiofrequency Neurotomy for a Patient with Deep Brain Stimulators: Proposed Safety Guidelines
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Conclusions. Radiofrequency medial branch neurotomy was performed on a patient with two deep brain stimulators with a satisfactory clinical outcome, and no adverse sequelae. Additional study is warranted regarding the safety and compatibility of brain neurostimulators and radiofrequency interventions.
Source: Pain Medicine - September 8, 2009 Category: Anesthesiology Authors: Michael D. Osborne Source Type: journals
A Unique Presentation of Complex Regional Pain Syndrome Type I Treated with a Continuous Sciatic Peripheral Nerve Block and Parenteral Ketamine Infusion: A Case Report
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Conclusion. This case suggests therapeutic benefit from aggressive treatment of both the peripheral and central components of CRPS.
Source: Pain Medicine - September 8, 2009 Category: Anesthesiology Authors: Adam Everett, Brian Mclean, Anthony Plunkett, Chester Buckenmaier Source Type: journals
