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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 27.

Anesthetic management of a patient with Alport-leiomyomatosis syndromeemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We report the anesthetic management of esophagectomy for a patient with Alport-leiomyomatosis syndrome. A 23-year-old woman complained of dysphagia and severe chest pain. Her chest X-ray, computed tomography (CT), and magnetic resonance imaging (MRI) showed an enlarged esophagus, in contact with the trachea, heart, aorta, and large vessels. She frequently experienced severe asthma attacks. Because various risks in both respiration and circulation, especially in anesthesia induction, were of concern, her right femoral vessels were exposed, for the emergency use of percutaneous cardiopulmonary support (PCPS), prior to an...
Source: Journal of Anesthesia - August 14, 2009 Category: Anesthesiology Tags: Journal of Anesthesia Source Type: journals

Successful extracorporeal membranous oxygenation for a patient with life-threatening transfusion-related acute lung injuryemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  A case of transfusion-related acute lung injury (TRALI) that was successfully treated with extracorporeal membranous oxygenation (ECMO) is reported. A 58-year-old male patient underwent hepatectomy, and pulmonary edema occurred after the administration of fresh-frozen plasma and packed red cells. In the postoperative period, the impaired oxygenation progressively worsened, resulting in life-threatening hypoxemia, despite vigorous treatments. ECMO was therefore applied to the patient as a method of safe emergency support. Aggressive treatments under ECMO led to the successful improvement of the impai...
Source: Journal of Anesthesia - August 14, 2009 Category: Anesthesiology Tags: Journal of Anesthesia Source Type: journals

Atracurium during induced hyperthermiaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  During hyperthermic intraperitoneal chemotherapy (HIPEC), we observed a partial recovery from neuromuscular block in a hyperthermic patient after hours of monitored adequate surgical relaxation and continuous infusion of atracurium during normothermia. This recovery is indicative of the higher clearance of atracurium during hyperthermia. This case report emphasizes the clinical relevance of the well-known temperature dependence of the Hofmann elimination of atracurium. Moreover, this report illustrates the importance of monitoring muscle relaxation during HIPEC. Clinicians should be aware that the u...
Source: Journal of Anesthesia - August 14, 2009 Category: Anesthesiology Tags: Journal of Anesthesia Source Type: journals

Volume manipulation by phlebotomy for cesarean section in a patient with pulmonary hypertensionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We describe a successful case of cesarean section performed under general anesthesia in a parturient with pulmonary hypertension. A distinctive feature of our management was active blood volume manipulation by phlebotomy and reinfusion of the blood. Just after the baby was delivered, about 250 ml of blood was phlebotomized to counteract autotransfusion by the contracting uterus. We stopped phlebotomy at this volume because moderate systemic hypotension occurred. The blood was slowly infused, with transesophageal echocardiography used to evaluate right ventricle filling. The patient was hemodynamically stable during th...
Source: Journal of Anesthesia - August 14, 2009 Category: Anesthesiology Tags: Journal of Anesthesia Source Type: journals

Anesthetic management of apicoaortic bypass in patients with severe aortic stenosisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  Apicoaortic bypass (AAB), or apicoaortic conduit insertion, is a conventional surgical method that has been regaining attention due to the aging population and the increasing number of repeat surgeries. The indication for the procedure has been extended as an alternative for aortic stenosis when the usual sternotomy or aortic clamping is considered to be difficult, e.g., in patients with severe calcification of the ascending aorta (porcelain aorta), or in patients with a patent coronary artery bypass graft located adjacent to the posterior surface of the sternum. Herein, we report our recent anesthe...
Source: Journal of Anesthesia - August 14, 2009 Category: Anesthesiology Tags: Journal of Anesthesia Source Type: journals

Anesthetic management of a child with Langer-Giedion (TRPS II) syndromeemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We describe the anesthetic and perioperative management of a child with Langer-Giedion syndrome (trichorhinophalangeal syndrome type II). This is a very rare genetic syndrome caused by 8q chromosome deletion. The clinical features of this syndrome include craniofacial and urogenital abnormities, variable postnatal growth deficiency with mental retardation, multiple exostoses, hyperflexible joints, and recurrent respiratory tract infections. Potential perioperative problems are highlighted. Content Type Journal ArticleCategory Clinical ReportDOI 10.1007/s00540-009-0779-7Authors Pavel Michalek, Antrim Area Hospital D...
Source: Journal of Anesthesia - August 14, 2009 Category: Anesthesiology Tags: Journal of Anesthesia Source Type: journals

Rapid response systememail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  There is growing evidence that early detection and response to physiological deterioration can improve outcomes for hospitalized infants, children, and adults. A rapid response system (RRS) is a multidisciplinary system to decrease the incidence of in-hospital cardiopulmonary arrests by detecting a crisis event and triggering a response and by dispatching a responding team. For quality improvement of the system, a review mechanism is vital to identify opportunities for preventing future events or improving response after crises occur. The whole system requires an administrative component that overse...
Source: Journal of Anesthesia - August 14, 2009 Category: Anesthesiology Tags: Journal of Anesthesia Source Type: journals

Protective effects of the free radical scavenger edaravone against glutamate neurotoxicity in nearly pure neuronal cultureemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion  Edaravone mainly showed a prophylactic effect on neurons against glutamate neurotoxicity, possibly through the inhibition of necrosis via the suppression of ROS production. However, for a protective effect, a higher, supraclinical concentration was required, compared to the concentrations producing a protective effect in glial and endothelial cells in previous studies. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00540-009-0766-zAuthors Kenjiro Hisano, Hokkaido University Graduate School of Medicine Department of Anesthesiology and Critical Care Medicine N15 W7, Kita-ku...
Source: Journal of Anesthesia - August 14, 2009 Category: Anesthesiology Tags: Journal of Anesthesia Source Type: journals

Dexmedetomidine-induced cerebral hypoperfusion exacerbates ischemic brain injury in ratsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion  Hypertension following the administration of high-dose dexmedetomidine is associated with cerebral hypoperfusion and the exacerbation of ischemic brain injury, possibly through alpha-2-induced cerebral vasoconstriction. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00540-009-0777-9Authors Takaaki Nakano, Kitasato University School of Medicine Department of Anesthesiology 1-15-1 Kitasato Sagamihara 228-8555 JapanHirotsugu Okamoto, Kitasato University School of Medicine Department of Anesthesiology 1-15-1 Kitasato Sagamihara 228-8555 Japan Journal Journal of Anesthes...
Source: Journal of Anesthesia - August 14, 2009 Category: Anesthesiology Tags: Journal of Anesthesia Source Type: journals

Use of Intralipid in an infant with impending cardiovascular collapse due to local anesthetic toxicityemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  Local anesthetic-associated cardiac toxicity following caudal epidural blockade is, fortunately, a rare event. Prompt recognition and early treatment is the key to successful resuscitation. Early use of the lipid emulsion Intralipid in bupivacaine-induced cardiac toxicity may lead to a good outcome. Content Type Journal ArticleCategory Clinical ReportDOI 10.1007/s00540-009-0754-3Authors Shailesh Shah, Arkansas Children’s Hospital/University of Arkansas for Medical Sciences Little Rock AR USASenthil Gopalakrishnan, Arkansas Children’s Hospital/University of Arkansas for Medical Sciences Little...
Source: Journal of Anesthesia - August 14, 2009 Category: Anesthesiology Tags: Journal of Anesthesia Source Type: journals

The impact of two arterial catheters, different in diameter and length, on postcannulation radial artery diameter, blood flow, and occlusion in atherosclerotic patientsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion  A 22-gauge catheter for radial arterial cannulation in patients with atherosclerosis provides unchanged postcannulated radial artery diameter, decreases postcannulation complications, and improves the first-attempt success rate. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00540-009-0753-4Authors H. Evren Eker, Ankara University School of Medicine Department of Anesthesiology and ICM Ankara TurkeyAcar Tuzuner, Ankara University School of Medicine Department of General Surgery Ankara TurkeyAli Abbas Yilmaz, Ankara University School of Medicine Department of Anesthesiology...
Source: Journal of Anesthesia - August 14, 2009 Category: Anesthesiology Tags: Journal of Anesthesia Source Type: journals

A review of perioperative complications during frameless stereotactic surgery: our institutional experienceemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion  Awareness and vigilance can help in the early identification and better management of the above intraoperative complications. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00540-009-0759-yAuthors Zulfiqar Ali, All India Institute of Medical Sciences Department of Neuroanaesthesiology, Neurosciences Center 7th floor New Delhi 110029 IndiaHemanshu Prabhakar, All India Institute of Medical Sciences Department of Neuroanaesthesiology, Neurosciences Center 7th floor New Delhi 110029 IndiaParmod K. Bithal, All India Institute of Medical Sciences Department of Neuroanaesthesiolog...
Source: Journal of Anesthesia - August 14, 2009 Category: Anesthesiology Tags: Journal of Anesthesia Source Type: journals

Treat Mind, Body in RA Patients: Studyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Title: Treat Mind, Body in RA Patients: StudyCategory: Health NewsCreated: 8/13/2009 1:08:00 PMLast Editorial Review: 8/14/2009
Source: MedicineNet Chronic Pain General - August 14, 2009 Category: Anesthesiology Source Type: consumer

Exercise May Help in Leukemia Recoveryemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Title: Exercise May Help in Leukemia RecoveryCategory: Health NewsCreated: 8/13/2009 1:08:00 PMLast Editorial Review: 8/14/2009
Source: MedicineNet Chronic Pain General - August 14, 2009 Category: Anesthesiology Source Type: consumer

Chronic pain after cardiac surgery: a prospective studyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In conclusion, we observed a lower prevalence of chronic pain after cardiac surgery than in previous studies. Still, more than one out of 10 patients reported chronic pain after cardiac surgery. Chronic pain appears to affect HRQOL. Thus, given the large number of patients subjected to cardiac surgery, this study confirms that chronic pain after cardiac surgery is an important health care issue.
Source: Acta Anaesthesiologica Scandinavica - August 13, 2009 Category: Anesthesiology Authors: K. H. GJEILO, P. KLEPSTAD, A. WAHBA, S. LYDERSEN, R. STENSETH Source Type: journals

[Adrenal function after induction of cardiac surgery patients with etomidate: A retrospective study.]email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSION: A high incidence of relative adrenal failure was observed in selected cardiac surgery patients with acute postoperative circulatory failure. PMID: 19683891 [PubMed - as supplied by publisher]
Source: Annales Francaises d'Anesthesie et de Reanimation - August 13, 2009 Category: Anesthesiology Authors: Seravalli L, Pralong F, Revelly JP, Que YA, Chollet M, Chioléro R Tags: Ann Fr Anesth Reanim Source Type: journals

Review: Diagnosis and management of neuropathic painemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Source: BMJ Area: News This BMJ review on the recognition and management of neuropathic pain addresses the following questions:   . What is neuropathic pain and who gets it? . How common is neuropathic pain? . How does neuropathic pain present in clinical practice? . How is neuropathic pain diagnosed? . What are the personal and societal costs of neuropathic pain? . What is a sensible therapeutic approach for patients with neuropathic pain? . What are the recommendations from clinical guidelines and algorithms? . Is there a role for non-pharmacological treatme...
Source: NeLM - Pain control - August 13, 2009 Category: Anesthesiology Source Type: organizations

Javelin Pharmaceuticals Reports Ereska (Intranasal Ketamine) Phase III Trial Results In Postoperative Orthopedic Painemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Javelin Pharmaceuticals, Inc. (NYSE Amex: JAV - News) today described its initial review of top line results from a Phase III study of Ereska™ (intranasal ketamine 30mg). This randomized, multicenter, double-blind, 1:1 placebo-controlled study assessed the safety and analgesic efficacy of repeated doses of Ereska over 6 hours in 259 patients with acute moderate-to-severe pain following orthopedic surgery.
Source: Pain / Anesthetics News From Medical News Today - August 13, 2009 Category: Anesthesiology Tags: Bones / Orthopaedics Source Type: news

Hematomaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Title: HematomaCategory: Diseases and ConditionsCreated: 8/13/2009Last Editorial Review: 8/13/2009
Source: MedicineNet Chronic Pain General - August 13, 2009 Category: Anesthesiology Source Type: consumer

Are we getting anywhere in human pain genetics?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Over the past decade, the ready availability of non-invasive DNA sampling, genotyping cores and bioinformatics expertise has allowed pain researchers with access to patient cohorts (and human normals) to perform single nucleotide polymorphism (SNP)-based genetic association studies. Although genetic research in rodents – transgenic, linkage mapping and microarray studies – would predict the existence of many hundreds of pain-relevant genes, current work in humans has focused on a handful of genes, especially COMT (encoding catechol-O-methyltransferase), GCH1 (encoding GTP cyclohydrolase 1), and OPRM1 (encoding the μ-o...
Source: Pain - August 13, 2009 Category: Anesthesiology Authors: Jeffrey S. Mogil Tags: Commentaries Source Type: journals

Sparing the larynx during gynecological laparoscopy: a randomized trial comparing the LMA Supreme™ and the ETTemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We designed a prospective randomized single-blind study to compare efficiency and post-operative upper airway morbidity when the laryngeal mask airway (LMA) Supreme[trade] is used as an alternative to the endotracheal tube (ETT). One hundred and thirty-eight elective pelvic laparoscopic ASA I[ndash]II female patients were assigned to receive either the LMA Supreme® or the ETT for airway management. Balanced anesthesia and ventilation techniques were standardized to control end-tidal CO2 and BIS value in the range 4.5[ndash]5 kPa and 40[ndash]50, respectively, and to maintain adequate hemodynamic stability. A single surgeo...
Source: Acta Anaesthesiologica Scandinavica - August 12, 2009 Category: Anesthesiology Authors: W. ABDI, R. AMATHIEU, A. ADHOUM, C. PONCELET, V. SLAVOV, W. KAMOUN, X. COMBES, G. DHONNEUR Source Type: journals

The GlideScope Ranger® video laryngoscope can be useful in airway management of entrapped patientsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This study suggests that the Glidescope Ranger® may be merited in situations requiring endotracheal intubation by an experienced intubator in patient entrapment. Further studies are required to clarify whether performance in patients mimics that in a manikin.
Source: Acta Anaesthesiologica Scandinavica - August 12, 2009 Category: Anesthesiology Authors: A. R. NAKSTAD, M. SANDBERG Source Type: journals

Single vs. double stimulation during a lateral sagittal infraclavicular blockemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The objective of this study was to evaluate the influence of single vs. dual control during an ultrasound-guided lateral sagittal infraclavicular block on the efficacy of sensory block and the time of block onset. In a prospective manner, 60 adult patients scheduled for distal upper limb surgery were randomly allocated to single (Group S) or double stimulation (Group D) groups. A local anesthetic (LA) mixture of 20 ml of levobupivacaine 5 mg/ml and 20 ml of lidocaine 20 mg/ml with 5 [mu]g/ml epinephrine (total 40 ml) was administered in both groups. In the Group S following a median, an ulnar or a radial nerve response, th...
Source: Acta Anaesthesiologica Scandinavica - August 12, 2009 Category: Anesthesiology Authors: E. AKY[iota]LD[iota]Z, Y. GÜRKAN, Ç. ÇAĞLAYAN, M. SOLAK, K. TOKER Source Type: journals

Glutamine administration in patients undergoing cardiac surgery and the influence on blood glutathione levelsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Cardiac surgery with an extracorporeal circulation cardiopulmonary bypass (CPB) is characterized by an oxidative stress response. Glutathione (GSH) belongs to the major antioxidative defense. In metabolic stress, glutamine (GLN) may be the rate-limiting factor of GSH synthesis. Decreased GLN plasma levels were observed after various critical states. We evaluated, in patients undergoing open heart surgery with CPB, the effects of a peri-operative GLN supplementation on GSH in whole blood and assessed their influence on the Sequential Organ Failure Assessment score and the intensive care unit length of stay. In this prospect...
Source: Acta Anaesthesiologica Scandinavica - August 12, 2009 Category: Anesthesiology Authors: J. M. ENGEL, J. MÜHLING, M. KWAPISZ, M. HEIDT Source Type: journals

Life-threatening systemic toxicity and airway compromise from a common European adder bite to the tongueemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
A 24-year-old man was bit on the tongue by a European common adder. Within 15 min following envenomation, he experienced tongue swelling, hypotension and impaired consciousness. Antihistamine, corticosteroid and crystalloids were administered. Within 105 min of envenomation, increasing oral, pharyngeal and facial oedema compromised the airway, leading to respiratory failure, concomitant with circulatory failure related to hypoxaemia and systemic toxic effects. Acute tracheotomy secured the airway, and two doses of antivenom successfully treated the systemic, toxic effects. The reaction was severe due to rapid and suspected...
Source: Acta Anaesthesiologica Scandinavica - August 12, 2009 Category: Anesthesiology Authors: L. C. G. HOEGBERG, C. L. JESSEN, K. LAMBERTSEN, J. STENSBALLE Source Type: journals

Effect of P6 acustimulation on post-operative nausea and vomiting in patients undergoing a laparoscopic cholecystectomyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Non-pharmacologic techniques such as electrical acustimulation may mitigate post-operative nausea and vomiting (PONV). The primary purpose of this study was to investigate the effectiveness of acustimulation on attenuating PONV. Moreover, we tested whether a pre- or a post-induction application of acustimulation results in differences in PONV reduction. In this prospective, double-blind, randomized, controlled trial, we studied 200 patients undergoing a laparoscopic cholecystectomy during propofol (induction) fentanyl/isoflurane/atracurium (maintenance) anaesthesia. In the acustimulation group (n=101), subdivided into grou...
Source: Acta Anaesthesiologica Scandinavica - August 12, 2009 Category: Anesthesiology Authors: U. H. FREY, M. FUNK, C. LÖHLEIN, J. PETERS Source Type: journals

The effects of obstructive jaundice on the pharmacodynamics of propofol: does the sensitivity of intravenous anesthetics change among icteric patients?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Some studies suggest that certain clinical symptoms of cholestasis, such as fatigue and pruritus, result from altered neurotransmission. Patients with obstructive jaundice also have labile blood pressure and heart rate. In the present study, the authors investigated whether obstructive jaundice affects a patient's sensitivity to hypnotics and the haemodynamic profile of propofol. Thirty-six ASA physical status I/II/III patients with serum total bilirubin (TBL) from 7.8 to 362.7 [mu]mol/l scheduled for bile duct surgery were recruited. A computer-controlled propofol infusion programmed for effect site target was used to rap...
Source: Acta Anaesthesiologica Scandinavica - August 12, 2009 Category: Anesthesiology Authors: J. C. SONG, M. Z. ZHANG, Z. J. LU, L. Q. YANG, J. G. SONG, Y. M. SUN, W. F. YU Source Type: journals

Measurements of functional residual capacity during intensive care treatment: the technical aspects and its possible clinical applicationsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Direct measurement of lung volume, i.e. functional residual capacity (FRC) has been recommended for monitoring during mechanical ventilation. Mostly due to technical reasons, FRC measurements have not become a routine monitoring tool, but promising techniques have been presented. We performed a literature search of studies with the key words 'functional residual capacity' or 'end expiratory lung volume' and summarize the physiology and patho-physiology of FRC measurements in ventilated patients, describe the existing techniques for bedside measurement, and provide an overview of the clinical questions that can be addressed...
Source: Acta Anaesthesiologica Scandinavica - August 12, 2009 Category: Anesthesiology Authors: H. HEINZE, W. EICHLER Source Type: journals

Active cooling in traumatic brain-injured patients: a questionable therapy?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Hypothermia is shown to be beneficial for the outcome after a transient global brain ischaemia through its neuroprotective effect. Whether this is also the case after focal ischaemia, such as following a severe traumatic brain injury (TBI), has been investigated in numerous studies, some of which have shown a tendency towards an improved outcome, whereas others have not been able to demonstrate any beneficial effect. A Cochrane report concluded that the majority of the trials that have already been published have been of low quality, with unclear allocation concealment. If only high-quality trials are considered, TBI patie...
Source: Acta Anaesthesiologica Scandinavica - August 12, 2009 Category: Anesthesiology Authors: P.-O. GRÄNDE, P. REINSTRUP, B. ROMNER Source Type: journals

Improved outcome after trauma care in university-level intensive care unitsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Centralized trauma care has been shown to be associated with improved patient outcome. We compared the outcomes of trauma patients in relation to the size of the intensive care unit (ICU) using a large Finnish database. A national prospectively collected ICU data registry was used for analysis. All adult trauma admissions excluding isolated head trauma and burns registered from July 1999 to December 2006 were analyzed. Data from 22 ICUs were available. The non-university-affiliated units were categorized according to the number of beds and referral population as small, mid size and large. Acute physiology and chronic healt...
Source: Acta Anaesthesiologica Scandinavica - August 12, 2009 Category: Anesthesiology Authors: T. I. ALA-KOKKO, P. OHTONEN, J. KOSKENKARI, J. J. LAURILA Source Type: journals

Levosimendan cardioprotection in acutely β-1 adrenergic receptor blocked open chest pigsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Levosimendan and volatile anesthetics have myocardial pre-conditioning effects. [beta]-1 adrenergic receptor antagonists may inhibit the protective effect of volatile anesthetics. No information exists as to whether this also applies to the pre-conditioning effect of levosimendan. We therefore investigated whether levosimendan added to metoprolol would demonstrate a cardioprotective effect. Three groups of anesthetized open chest pigs underwent 30 min of myocardial ischemia and 90 min of reperfusion by temporary occlusion of the largest side branch from the circumflex artery or the left anterior descending artery. One grou...
Source: Acta Anaesthesiologica Scandinavica - August 12, 2009 Category: Anesthesiology Authors: C. METZSCH, R. LINNÉR, S. STEEN, Q. LIAO, L. ALGOTSSON Source Type: journals

Visualization of alveolar recruitment in a porcine model of unilateral lung lavage using 3He-MRIemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In the acute respiratory distress syndrome potentially recruitable lung volume is currently discussed. 3He-magnetic resonance imaging (3He-MRI) offers the possibility to visualize alveolar recruitment directly. With the approval of the state animal care committee, unilateral lung damage was induced in seven anesthetized pigs by saline lavage of the right lungs. The left lung served as an intraindividual control (healthy lung). Unilateral lung damage was confirmed by conventional proton MRI and spiral-CT scanning. The total aerated lung volume was determined both at a positive end-expiratory pressure (PEEP) of 0 and 10 mbar...
Source: Acta Anaesthesiologica Scandinavica - August 12, 2009 Category: Anesthesiology Authors: A. RUDOLPH, K. MARKSTALLER, K. K. GAST, M. DAVID, W. G. SCHREIBER, B. EBERLE Source Type: journals

Late sensory function after intraoperative capsaicin wound instillationemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Intense capsaicin-induced C-fiber stimulation results in reversible lysis of the nerve soma, thereby making capsaicin wound instillation of potential interest for the treatment of post-operative pain. Clinical histological and short-term sensory studies suggest that the C-fiber function is partly re-established after skin injection of capsaicin. However, no study has evaluated the long-term effects of wound instillation of purified capsaicin on sensory functions. Patients included in a double-blind placebo-controlled randomized study of the analgesic effect of capsaicin after groin hernia repair were examined by quantitati...
Source: Acta Anaesthesiologica Scandinavica - August 12, 2009 Category: Anesthesiology Authors: E. K. AASVANG, J. B. HANSEN, H. KEHLET Source Type: journals

Brain death and its implications for management of the potential organ donoremail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The systemic physiologic changes that occur during and after brain death affect all organs suitable for transplantation. Major changes occur in the cardiovascular, pulmonary, endocrine, and immunological systems, and, if untreated may soon result in cardiovascular collapse and somatic death. Understanding these complex physiologic changes is mandatory for developing effective strategies for donor resuscitation and management in such a way that the functional integrity of potentially transplantable organs is maintained. This review elucidates these physiological changes and their consequences, and based on these consequence...
Source: Acta Anaesthesiologica Scandinavica - August 12, 2009 Category: Anesthesiology Authors: J. F. BUGGE Source Type: journals

Automated pre-ejection period variation predicts fluid responsiveness in low tidal volume ventilated pigsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The respiratory variation in the pre-ejection period ([Delta]PEP) has been used to predict fluid responsiveness in mechanically ventilated patients. Recently, we automated this parameter and indexed it to tidal volume (PEPV) and showed that it was a reliable predictor for post-cardiac surgery, mainly paced, patients ventilated with low tidal volumes. The aims of the present animal study were to investigate PEPV's ability to predict fluid responsiveness under different fluid loading conditions and natural heart rates during low tidal volume ventilation (6 ml/kg) and to compare the performance of PEPV with other markers of f...
Source: Acta Anaesthesiologica Scandinavica - August 12, 2009 Category: Anesthesiology Authors: S. T. VISTISEN, J. KOEFOED-NIELSEN, A. LARSSON Source Type: journals

In the September 2009 BJA ...email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Source: British Journal of Anaesthesia - August 12, 2009 Category: Anesthesiology Tags: In This Issue Source Type: journals

Does strict glucose control improve outcome?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Source: British Journal of Anaesthesia - August 12, 2009 Category: Anesthesiology Authors: Webster, N. R., Galley, H. F. Tags: Editorial Source Type: journals

Does regional anaesthesia improve outcome after total hip arthroplasty? A systematic reviewemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Total hip arthroplasty (THA) is amenable to a variety of regional anaesthesia (RA) techniques that may improve patient outcome. We sought to answer whether RA decreased mortality, cardiovascular morbidity, deep venous thrombosis (DVT) and pulmonary embolism (PE), blood loss, duration of surgery, pain, opioid-related adverse effects, cognitive defects, and length of stay. We also questioned whether RA improved rehabilitation. To do so, we performed a systematic review of the contemporary literature to compare general anaesthesia (GA) and RA and also systemic and regional analgesia for THA. To reflect contemporary surgical a...
Source: British Journal of Anaesthesia - August 12, 2009 Category: Anesthesiology Authors: Macfarlane, A. J. R., Prasad, G. A., Chan, V. W. S., Brull, R. Tags: Review Article Source Type: journals

Evaluation of stroke volume variation obtained by arterial pulse contour analysis to predict fluid responsiveness intraoperativelyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions This prospective, interventional observer-blinded study demonstrates that SVV obtained by APCO, using the FloTracTM/VigileoTM system, is not a reliable predictor of fluid responsiveness in the setting of major abdominal surgery.
Source: British Journal of Anaesthesia - August 12, 2009 Category: Anesthesiology Authors: Lahner, D., Kabon, B., Marschalek, C., Chiari, A., Pestel, G., Kaider, A., Fleischmann, E., Hetz, H. Tags: Cardiovascular Source Type: journals

Audit of anaesthetist-performed echocardiography on perioperative management decisions for non-cardiac surgeryemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions Anaesthetist-performed point-of-care TTE and thoracic ultrasound may have a high clinical impact on the perioperative management of patients scheduled for non-cardiac surgery.
Source: British Journal of Anaesthesia - August 12, 2009 Category: Anesthesiology Authors: Canty, D. J., Royse, C. F. Tags: Clinical Practice Source Type: journals

Droperidol has comparable clinical efficacy against both nausea and vomitingemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions We conclude that droperidol prevents PON and POV equally well, yet its duration of action is short-lived.
Source: British Journal of Anaesthesia - August 12, 2009 Category: Anesthesiology Authors: Apfel, C. C., Cakmakkaya, O. S., Frings, G., Kranke, P., Malhotra, A., Stader, A., Turan, A., Biedler, A., Kolodzie, K. Tags: Clinical Practice Source Type: journals

Influence of patient-controlled i.v. analgesia with opioids on supraventricular arrhythmias after pulmonary resectionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions PCA with opioids (fentanyl and tramadol) can reduce postoperative SVA after pulmonary resection compared with PCEA with ropivacaine.
Source: British Journal of Anaesthesia - August 12, 2009 Category: Anesthesiology Authors: Jiang, Z., Dai, J. Q., Shi, C., Zeng, W. S., Jiang, R. C., Tu, W. F. Tags: Clinical Practice Source Type: journals

Meperidine-induced serotonin syndrome in a susceptible patientemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This report heightens appreciation of population at risk and also recognition of potential toxicity in meperidine.
Source: British Journal of Anaesthesia - August 12, 2009 Category: Anesthesiology Authors: Guo, S.-L., Wu, T.-J., Liu, C.-C., Ng, C.-C., Chien, C.-C., Sun, H.-L. Tags: Clinical Practice Source Type: journals

Pre-hospital tracheal intubation in patients with traumatic brain injury: systematic review of current evidenceemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions Overall, the available evidence did not support any benefit from pre-hospital intubation and mechanical ventilation after TBI. Additional arguments need to be taken into account, including medical and procedural aspects.
Source: British Journal of Anaesthesia - August 12, 2009 Category: Anesthesiology Authors: von Elm, E., Schoettker, P., Henzi, I., Osterwalder, J., Walder, B. Tags: Critical Care Source Type: journals

Bispectral and spectral entropy indices at propofol-induced loss of consciousness in young and elderly patientsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions In adults undergoing propofol induction, BIS, SE, and RE indices at LOC are significantly affected by age.
Source: British Journal of Anaesthesia - August 12, 2009 Category: Anesthesiology Authors: Lysakowski, C., Elia, N., Czarnetzki, C., Dumont, L., Haller, G., Combescure, C., Tramer, M. R. Tags: Neurosciences And Neuroanaesthesia Source Type: journals

Time delay of electroencephalogram index calculation: analysis of cerebral state, bispectral, and Narcotrend indices using perioperatively recorded electroencephalographic signalsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions Our results may show a limitation of the value of electronic EEG indices in prevention of awareness with recall. Furthermore, due to different time delays for ascending and descending values, the results of pharmacodynamic studies may be influenced by this phenomenon.
Source: British Journal of Anaesthesia - August 12, 2009 Category: Anesthesiology Authors: Zanner, R., Pilge, S., Kochs, E. F., Kreuzer, M., Schneider, G. Tags: Neurosciences And Neuroanaesthesia Source Type: journals

A randomized prospective study comparing two flexible epidural catheters for labour analgesiaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions There were no differences in the initial analgesia success rate, complications, or labour analgesia between end-hole vs multi-hole flexible epidural catheters.
Source: British Journal of Anaesthesia - August 12, 2009 Category: Anesthesiology Authors: Spiegel, J. E., Vasudevan, A., Li, Y., Hess, P. E. Tags: Obstetrics Source Type: journals

Cardiopulmonary arrest in pregnancy: two case reports of successful outcomes in association with perimortem Caesarean deliveryemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In this report, we describe two cases of cardiac arrest in pregnancy in which a perimortem Caesarean was performed as part of the resuscitation process and was associated with excellent maternal and neonatal outcomes. We discuss some of the issues surrounding the performance of a perimortem Caesarean delivery that were relevant to this case, including experience from the training that is provided in our institution.
Source: British Journal of Anaesthesia - August 12, 2009 Category: Anesthesiology Authors: McDonnell, N. J. Tags: Obstetrics Source Type: journals

Prevention of propofol-induced pain in children: combination of alfentanil and lidocaine vs alfentanil or lidocaine aloneemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions Our study demonstrated that the combination treatment of two different analgesic modalities, alfentanil and lidocaine, could prevent the moderate and severe pain on propofol injection, and reduce the incidence of mild pain compared with each drug alone.
Source: British Journal of Anaesthesia - August 12, 2009 Category: Anesthesiology Authors: Kwak, H. J., Min, S. K., Kim, J. S., Kim, J. Y. Tags: Paediatrics Source Type: journals

Perioperative use of dexmedetomidine in an infant with familial dysautonomiaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We report the safe use of dexmedetomidine in an infant with this extremely rare condition.
Source: British Journal of Anaesthesia - August 12, 2009 Category: Anesthesiology Authors: Abulhasan, Y., Buu, N., Frigon, C. Tags: Paediatrics Source Type: journals