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This page shows you the 20 most read items in the past 30 days within this specialty in the MedWorm directory.

Perioperative Management of the Adult with Cystic Fibrosis.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Since cystic fibrosis (CF) was first differentiated from celiac disease in 1938, the medical care of patients with CF has substantially improved. These improvements have resulted in a significant increase in median survival and the quality of life experienced by patients. The resultant increase in survival has caused the "average" CF patient to be a young adult and not a child. The gene that causes CF was first identified in 1989 and is the first gene discovered by positional cloning. Unfortunately, gene therapy for CF has not been successful, although it continues to hold great promise for future patient care. Althoug...
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Huffmyer JL, Littlewood KE, Nemergut EC Tags: Anesth Analg Source Type: journals

ACR: Drug Delivers Two-Fisted Punch to Fibromyalgia (CME/CE)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
PHILADELPHIA (MedPage Today) -- Milnacipran (Savella) improved pain and mental functioning in patients suffering from fibromyalgia, researchers said here. (Source: MedPage Today Pain Management)
Source: MedPage Today Pain Management - October 23, 2009 Category: Anesthesiology Source Type: news

62-Year-Old Man Becomes First Patient In China Implanted With Rechargeable Neurostimulator For Chronic PainEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
St. Jude Medical, Inc. (NYSE:STJ) announced that a 62-year-old man from Shenzhen, Guangdong province has become the first patient in China to be implanted with the Eon™ neurostimulator, a rechargeable device used to help manage chronic pain. Despite prior back surgeries, the patient suffered from chronic back pain for more than a decade. (Source: Pain / Anesthetics News From Medical News Today)
Source: Pain / Anesthetics News From Medical News Today - November 19, 2009 Category: Anesthesiology Tags: Pain / Anesthetics Source Type: news

Pain From Breast Cancer Treatment Can Linger For Years, Study FindsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Nearly half of all breast cancer patients experienced chronic pain two to three years after treatment and more than half felt discomfort, according to a study by Danish researchers published Tuesday in the Journal of the American Medical Association, the New York Times reports. (Source: Pain / Anesthetics News From Medical News Today)
Source: Pain / Anesthetics News From Medical News Today - November 13, 2009 Category: Anesthesiology Tags: Breast Cancer Source Type: news

Acetaminophen May Be Linked To Asthma In Children And AdultsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
New research shows that the widely used pain reliever acetaminophen may be associated with an increased risk of asthma and wheezing in both children and adults exposed to the drug. Researchers from the University of British Columbia, Vancouver, BC, Canada, conducted a systematic review and metaanalysis of 19 clinical studies (total subjects=425,140) that compared the risk of asthma or wheezing with acetaminophen exposure. (Source: Pain / Anesthetics News From Medical News Today)
Source: Pain / Anesthetics News From Medical News Today - November 6, 2009 Category: Anesthesiology Tags: Pain / Anesthetics Source Type: news

Central sensory-motor deficit after uneventful single-dose spinal morphine administration in a patient with preexisting migraine headaches.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report a persisting central neurological deficit after single-dose spinal administration of 400 mug of morphine in a patient with no previous neurological condition. Hemiplegic migraine was thought to be present when the patient emerged from anesthesia. Weakness in the left quadriceps and saddle anesthesia of the perineum and urinary retention of central origin remained present 3 yr later. Over the 3 postoperative years, the patient was admitted to a neurological unit 5 times because of acute headache associated with complete left-sided hemiplegia. These symptoms resolved within 24 h of onset. Hemiplegic migraine was th...
Source: Anesthesia and Analgesia - October 23, 2009 Category: Anesthesiology Authors: Lentschener C, Dousset B, Zuber M, Ozier Y Tags: Anesth Analg Source Type: journals

Pelvic Girdle Pain and Low Back Pain in Pregnancy: A ReviewEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This article will focus on the diagnosis and management of PGP and PLBP, with discussion of terminology, epidemiology, risk factors, pathophysiology, and prognosis. (Source: Pain Practice)
Source: Pain Practice - October 26, 2009 Category: Anesthesiology Authors: Era Vermani, Rajnish Mittal, Andrew Weeks Source Type: journals

Occipital Nerve Stimulator Lead Pathway Length Changes with Volunteer Movement: An In Vitro StudyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Internal pulse generators in sites other than the buttock, including infraclavicular or low abdomen, may be associated with lower lead migration risk. There are many considerations when selecting insertion sites and lead pathways for occipital nerve stimulation. Implanters and patients may consider these results when contemplating surgical approaches to this challenging form of peripheral nerve stimulation. (Source: Pain Practice)
Source: Pain Practice - October 26, 2009 Category: Anesthesiology Authors: Terrence L. Trentman, Jeff T. Mueller, Deepesh M. Shah, Richard S. Zimmerman, Brie M. Noble Source Type: journals

The effect of a thoracic spinal block on fos expression in the lumbar spinal cord of the rat induced by a noxious electrical stimulus at the hindpaw.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: The increase in Fos-IR in Lamina V may have resulted from the interruption of a pain-modulating descending mechanism from the brain. A known modulating descending mechanism is the serotonergic system, controlled by the periaqueductal gray. This system inhibits the neurons in the superficial laminae. Another nonserotonergic system originates in the anterior pretectal nucleus. The latter facilitates neurons in the superficial laminae, while neurons in Lamina V are inhibited. We conclude that both systems are probably involved in the observed effects of the peripheral noxious stimulation given in the present mode...
Source: Anesthesia and Analgesia - October 23, 2009 Category: Anesthesiology Authors: Giele JL, Nabers AF, Veening JG, van Egmond J, Vissers KC Tags: Anesth Analg Source Type: journals

The effect of perioperative intravenous lidocaine on postoperative pain and immune function.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSION: The present findings indicate that preoperative and intraoperative IV lidocaine improves immediate postoperative pain management and reduces surgery-induced immune alterations. PMID: 19843784 [PubMed - in process] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - October 23, 2009 Category: Anesthesiology Authors: Yardeni IZ, Beilin B, Mayburd E, Levinson Y, Bessler H Tags: Anesth Analg Source Type: journals

Litigation related to drug errors in anaesthesia: an analysis of claims against the NHS in England 1995–2007Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Ninety-three claims (total cost £4 915 450) filed under 'anaesthesia' in the NHS Litigation Authority database between 1995 and 2007, alleging patient harm directly by drug administration error or by an allergic reaction, were analysed. Alleged errors were categorised using systems employed by the National Coordinating Council for Medication Error Reporting and Prevention, the American Society of Anesthesiologists Closed Claims Project and the UK Health and Safety Executive. The severity of outcome in each claim was categorised using adapted National Patient Safety Agency definitions. Sixty-two claims involved alleged dru...
Source: Anaesthesia - October 21, 2009 Category: Anesthesiology Authors: J. Cranshaw, K. J. Gupta, T. M. Cook Source Type: journals

Recombinant Activated Factor VII in Obstetric Hemorrhage: Experiences from the Australian and New Zealand Haemostasis Registry.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
CONCLUSIONS: The reported effect of rFVIIa in many, but not all, obstetric cases was positive. There was no mortality as a result of thromboembolic complications. Randomized, controlled trials are required to confirm its safety and efficacy and to assess the possibility that use at an earlier stage in treatment of severe postpartum hemorrhage may avoid the need to resort to postpartum hysterectomy for control of bleeding, thus preserving fertility. PMID: 19923520 [PubMed - as supplied by publisher] (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - November 20, 2009 Category: Anesthesiology Authors: Phillips LE, McLintock C, Pollock W, Gatt S, Popham P, Jankelowitz G, Ogle R, Cameron PA Tags: Anesth Analg Source Type: journals

A response to 'Evaluation of capsaicin ointment at the Korean hand acupressure point K-D2 for prevention of postoperative nausea and vomiting'Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Anaesthesia Volume 61, Issue 6, Page 617-617, Jun 2006 (Source: Anaesthesia)
Source: Anaesthesia - May 12, 2006 Category: Anesthesiology Source Type: journals

Study Links Herpes With Widespread Neuropathic PainEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Reactivation of genital herpes is linked in some cases with the emergence of widespread neuropathic pain, according to a Finnish study reported in The Journal of Pain. In the clinic at the University of Helsinki, 17 patients were examined who presented widespread chronic pain with no visible lesions in brain magnetic imaging. Because the majority had herpes simplex virus (HSV) infections, the researchers studied a possible association between herpes and neuropathic pain. (Source: Pain / Anesthetics News From Medical News Today)
Source: Pain / Anesthetics News From Medical News Today - July 22, 2008 Category: Anesthesiology Source Type: news

Perioperative management of outpatients with implantable cardioverter defibrillatorsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Purpose of review: Implantable cardioverter defibrillators (ICDs) are increasingly being placed in patients worldwide. These patients pose significant perioperative challenges and are at an increased risk of complications; the suitability of ambulatory surgery in this patient population remains controversial. The purpose of the present review is to examine the potential challenges and optimal perioperative care of patients with an ICD. Recent findings: The American Society of Anesthesiologists Advisory for the perioperative management of patients with cardiac rhythm management devices as well as the American College of Ca...
Source: Current Opinion in Anaesthesiology - November 11, 2009 Category: Anesthesiology Tags: Ambulatory anesthesia: Edited by Girish Joshi Source Type: journals

Fibromyalgia: From treatment to rehabilitationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Fibromyalgia is a clinical syndrome of chronic widespread pain and reduced pain thresholds to palpation. The pathophysiology remains unknown, but there is increasing evidence that peripheral and central sensitization cause an amplification of sensory impulses that may alter pain perception in fibromyalgia patients. Interventions to treat fibromyalgia should aim at different targets simultaneously in order to reduce peripheral and central sensitization. There are both pharmacologic and non-pharmacologic approaches with evidence for effectiveness in the treatment of fibromyalgia and its associated symptoms. Evidenc...
Source: European Journal of Pain Supplements - October 27, 2009 Category: Anesthesiology Authors: Marta Imamura, David A. Cassius, Felipe Fregni Source Type: journals

FDA Discusses Neuromed NDA Application For ExalgoEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Covidien (NYSE: COV) announced that on November 13, 2009, representatives of Neuromed discussed the pending New Drug Application (NDA) for the product candidate ExalgoTM (hydromorphone HCl extended release) tablets with staff from the United States Food and Drug Administration (FDA). Mallinckrodt Inc., a Covidien company, obtained the commercial rights to Exalgo in the United States from Neuromed Development Inc., a subsidiary of Neuromed Pharmaceuticals Ltd., in June 2009. (Source: Pain / Anesthetics News From Medical News Today)
Source: Pain / Anesthetics News From Medical News Today - November 18, 2009 Category: Anesthesiology Tags: Pain / Anesthetics Source Type: news

Ultrasound and facet blocks: A reviewEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Facet or zygapophysial joints are considered to be common sources of chronic spinal pain. In addition to causing localized spinal pain, facet joints may refer pain to adjacent structures. Cervical facet-joint pain may radiate to the head, neck, and shoulders. Thoracic facets may produce paraspinous mid-back pain with neuralgic characteristics; and lumbar facet joints may refer pain to the back, buttocks, and proximal lower extremities. Because the facet joint is innervated by the medial branches arising from the posterior rami of the spinal nerve at the same level and a level above the joint, LA blocks of these n...
Source: European Journal of Pain Supplements - October 27, 2009 Category: Anesthesiology Authors: Laura Bertini, M. Baciarello Source Type: journals

Locoregional anesthesia and anticoagulationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Abstract: Spinal hematoma is a rare and potentially catastrophic complication of spinal or epidural anesthesia. Risk factors include traumatic needle/catheter placement, sustained anticoagulation in an indwelling neuraxial catheter, and catheter removal during therapeutic levels of anticoagulation. Generally, a patient’s coagulation status should be optimized at the time of spinal or epidural needle/catheter placement, and the level of anticoagulation should be monitored during epidural catheterization. Signs of cord compression, such as severe back pain, progression of numbness or weakness, and bowel and bladder dysfunc...
Source: European Journal of Pain Supplements - October 27, 2009 Category: Anesthesiology Authors: Terese T. Horlocker Source Type: journals

Hemoglobin-based Oxygen Carriers: Current Status and Future DirectionsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Similarity of toxicities for molecularly dissimilar hemoglobin-based oxygen carriers and mitigation strategies were discussed at a National Institutes of Health/Food and Drug Administration-sponsored workshop. Finding appropriate clinical balance of risk:benefit remains challenging. (Source: Anesthesiology)
Source: Anesthesiology - October 24, 2009 Category: Anesthesiology Tags: Special Articles Source Type: journals