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Imaging of Endolymphatic and Perilymphatic Fluid after Intravenous Administration of Single-dose Gadodiamide.
Abstract To visualize endolymph as bright signal after intravenous injection of single-dose gadodiamide, we shortened the inversion time of heavily T<inf>2</inf>-weighted 3-dimensional (3D) fluid-attenuated inversion recovery (FLAIR) to 2050 ms. In 14 patients with suspected Ménière's disease, we observed high signal of vestibular endolymph in all ears, including 6 ears without vestibular endolymphatic hydrops. We observed high signal of cochlear endolymph in 17 ears with cochlear endolymphatic hydrops but not 11 ears without cochlear endolymphatic hydrops. PMID: 22790302 [PubMed - in process]
Source: Magnetic Resonance in Medical Sciences : MRMS - July 27, 2012 Category: Radiology Authors: Naganawa S, Yamazaki M, Kawai H, Bokura K, Sone M, Nakashima T Tags: Magn Reson Med Sci Source Type: research

Therapeutic Group in Speech Language and Hearing Sciences: literature review
CONCLUSION: there are a limited number of publications concerning the topic (28 articles). Most studies were conducted with adult audiences, followed by groups of children, adolescents and elderly, respectively. The index of articles involving family groups was low. Among the areas of Speech, Language has the largest number of publications involving groups, followed by the areas of Speech and Audiology. As for the year of publication, we noted that, in general, there has been a decline in the number of publications on the subject since the year 2007. We may conclude then that the number of publications on the therapeutic g...
Source: Revista CEFAC - July 27, 2012 Category: Speech Therapy Source Type: research

Speech and language therapy and humanization: perception of speech and language therapist of a public hospital
CONCLUSION: in what concerns the concept of humanization presented by the speech therapists, it is in consonance with what has been described in the National Politic of Humanization. About the criteria needed in order to guarantee a humanized assistance taking as reference the institution, the user and the professional, the interviewed subjects partially cited the principles of the National Policy of Humanization.
Source: Revista CEFAC - July 27, 2012 Category: Speech Therapy Source Type: research

Cochlear implantation in children with cochlear nerve deficiency: A report of nine cases
Conclusions: The decision to perform cochlear implantation in children with cochlear nerve deficiency must be undertaken with caution as it has limited effectiveness and uncertain cost-benefit.
Source: International Journal of Pediatric Otorhinolaryngology - July 27, 2012 Category: ENT & OMF Authors: Zhihua Zhang, Yun Li, Lingxiang Hu, Zhaoyan Wang, Qi Huang, Hao Wu Tags: Research papers Source Type: research

Cochlear implanted children present vocal parameters within normal standards
Conclusion: implanted children who participate in a (re) habilitation and follow-up program, can present vocal characteristics similar to those vocal characteristics of children with normal hearing.
Source: International Journal of Pediatric Otorhinolaryngology - July 27, 2012 Category: ENT & OMF Authors: Lourdes Bernadete Rocha de Souza, Maria Cecília Bevilacqua, Alcione Ghedini Brasolotto, Ana Cristina Coelho Tags: Research papers Source Type: research

Mutation detection in GJB2 gene among Malays with non-syndromic hearing loss
Conclusions: The types of GJB2 gene mutation were different and vary in Malay non-syndromic hearing loss as compared to the other races. Furthermore, the mutation did not associate with hearing loss in the population. Other related genes are believed to be involved and need to be sought in this group of patients.
Source: International Journal of Pediatric Otorhinolaryngology - July 27, 2012 Category: ENT & OMF Authors: Siti Aishah Zainal, Mohd Khairi Md Daud, Normastura Abd Rahman, Zafarina Zainuddin, Zilfalil Alwi Tags: Research papers Source Type: research

The spectrum of GJB2 mutations in the Iranian population with non-syndromic hearing loss—A twelve year study
Conclusion: Our data also show that there is a gradual decrease in the frequency of the c.35delG mutation and of GJB2-related deafness in general in a cline across Iran extending from the northwest to southeast.
Source: International Journal of Pediatric Otorhinolaryngology - July 27, 2012 Category: ENT & OMF Authors: Niloofar Bazazzadegan, Nooshin Nikzat, Zohreh Fattahi, Carla Nishimura, Nicole Meyer, Shima Sahraian, Payman Jamali, Mojgan Babanejad, Atie Kashef, Hilda Yazdan, Farahnaz Sabbagh Kermani, Maryam Taghdiri, Batool Azadeh, Faezeh Mojahedi, Atefeh Khoshaeen, Tags: Research papers Source Type: research

Measuring what matters: Effectively predicting language and literacy in children with cochlear implants
Conclusions: Before 24 months of age, the best predictor of later language success is language comprehension. In general, measures that index a child's cognitive processing of language are the most sensitive predictors of school-age language abilities.
Source: International Journal of Pediatric Otorhinolaryngology - July 27, 2012 Category: ENT & OMF Authors: Susan Nittrouer, Amanda Caldwell, Christopher Holloman Tags: Research papers Source Type: research

The conceptions of hearing impairment, causes and its management: A train survey
Conclusions: An awareness pamphlet targeting the myths can be distributed on train, role of an audiologist as a hearing professional can also be targeted in the pamphlets, language used in the advertisements and pamphlets should be culture and region specific, pictorial representation could be a better idea, the need for a healthy and comfortable communication has to be explained especially to the adults and geriatric population and the elderly persons must have both, the skills and the motivation to communicate in the external environment which must be conducive for communication .
Source: International Journal of Pediatric Otorhinolaryngology - July 27, 2012 Category: ENT & OMF Authors: Suman Kumar, Nachiketa Rout, Punam Kumari, Bhaskar Dey Tags: Research papers Source Type: research

Strengths and difficulties in children with cochlear implants – Comparing self-reports with reports from parents and teachers
Conclusions: Children with cochlear implants express greater concerns about their mental health than their parents and teachers do. This is important knowledge for adults in families, schools, and health care in order to support these children and offer treatment when needed.
Source: International Journal of Pediatric Otorhinolaryngology - July 27, 2012 Category: ENT & OMF Authors: Lena Anmyr, Kjerstin Larsson, Mariann Olsson, Anders Freijd Tags: Research papers Source Type: research

Minimal access and standard cochlear implantation: A comparative study
Abstract: Objective: To compare the operative times and complications between patients who underwent minimal access cochlear implantation and standard technique cochlear implantation.Methods: Patients who underwent unilateral cochlear implantation by a single surgeon from 2001 to 2010. The minimal access technique of an approximately 2.5–3cm post-auricular incision with creation of subperiosteal pocket for the device was compared to the longer standard “S” incision into the scalp (∼8–10cm) with bone well creation and suture fixation. Outcomes include operative times and complications.Results: There were 122 unila...
Source: International Journal of Pediatric Otorhinolaryngology - July 27, 2012 Category: ENT & OMF Authors: Jeremy D. Prager, Marci J. Neidich, Jonathan N. Perkins, Jareen Meinzen-Derr, John H. Greinwald Tags: Research papers Source Type: research

Surgical treatment of paediatric cholesteatoma: Long-term follow up in comparison with adults
Conclusion: Our results suggest that one-stage eradication of ACH and CCH in children using total reconstruction procedure (TRP) provide long-term improvement or preservation of hearing, with a low incidence of persistent or recurrent disease. No difference in surgical outcome between children and adults was found.
Source: International Journal of Pediatric Otorhinolaryngology - July 27, 2012 Category: ENT & OMF Authors: Lennart Edfeldt, Anders Kinnefors, Karin Strömbäck, Susanne Köbler, Helge Rask-Andersen Tags: Research papers Source Type: research

A postmeningitic cochlear implant patient who was postoperatively diagnosed as having X-linked agammaglobulinemia
Abstract: X-linked agammaglobulinemia (XLA) is caused by a mutation in the Bruton tyrosine kinase, leading to an arrest in B cell development. Consequently, patients with XLA show significant decreases in gammaglobulin. Here, we describe a child with postmeningitic deafness and XLA who underwent a cochlear implantation. His psychomotor development had been normal and his congenital immunodeficiency was noticed only postoperatively. Immunoglobulin replacement treatment was started, but he still suffered repeated infections. Eventually, his cochlear implant was removed. A preoperative check of immunological status might be a...
Source: Auris, Nasus, Larynx - July 27, 2012 Category: ENT & OMF Authors: Ryosei Minoda, Haruo Takahashi, Satoru Miyamaru, Masako Masuda, Toru Miwa, Tetsuji Sanuki, Toshinori Hirai, Eiji Yumoto Tags: Case reports Source Type: research

Cochlear implantation in a patient with superficial siderosis
We report the case of a 65-year-old woman with bilateral progressive sensorineural hearing loss caused by superficial siderosis who benefited significantly from cochlear implantation.
Source: Auris, Nasus, Larynx - July 27, 2012 Category: ENT & OMF Authors: Hisashi Sugimoto, Makoto Ito, Miyako Hatano, Tomokazu Yoshizaki Tags: Case reports Source Type: research

Re-implantation of the Rion E-type semi-implantable hearing aid: Status of long-term use and hearing outcomes in eight patients
Conclusions: Re-implantation of an IHA is beneficial and safe for patients. As the absence of active inflammation has a crucial effect on the period of use, re-implantation should be judged carefully after deterioration of the initial implant.
Source: Auris, Nasus, Larynx - July 27, 2012 Category: ENT & OMF Authors: Masahiro Komori, Naoaki Yanagihara, Yasuyuki Hinohira, Naohito Hato, Kiyofumi Gyo Tags: Otology/Neurotology Source Type: research

CRPD Passes Committee Vote, Next Stop is the Senate Floor
July 27, 2012 SENATE FOREIGN RELATIONS COMMITTEE SENDS THE CONVENTION ON THE RIGHTS OF PERSONS WITH DISABILITIES TO A FLOOR VOTE AT THE UNITED STATES SENATE   read more
Source: National Association of the Deaf - July 27, 2012 Category: Audiology Authors: admin Source Type: news

Congenital Deafness May Be Reversed By Gene Therapy
A new gene therapy approach can reverse hearing loss caused by a genetic defect in a mouse model of congenital deafness, according to a preclinical study published by Cell Press in the journal Neuron. The findings present a promising therapeutic avenue for potentially treating individuals who are born deaf...
Source: Health News from Medical News Today - July 27, 2012 Category: Consumer Health News Tags: Hearing / Deafness Source Type: news

A non-invasive Cochlear Microphonic measurement system
Abstract: The Cochlear Microphonic is one of the electrical potentials generated by the ear in response to audible stimuli. It is very difficult to measure the CM non-invasively because it has a very small magnitude (less than 1μV). A high Common Mode Rejection Ratio (CMRR) and very large bandwidth (5Hz–20kHz) biomedical amplifier system is presented to measure the signal. The system also uses a driven right leg circuit to increase the CMRR.
Source: Medical Engineering and Physics - July 27, 2012 Category: Biomedical Engineering Authors: Asim Masood, Paul D. Teal, Christopher Hollitt Tags: Technical Notes Source Type: research

Gene Therapy helps with Hearing Loss
(Ivanhoe Newswire) -- The sound of a horn beeping at you while driving, the chirping crickets after a huge rain storm, and your favorite new One Direction song -- imagine going through life not being able to hear any of it. That is a reality for those living with hearing loss. Now, researchers are trying new things to turn up the volume for the deaf.
Source: Medical Headlines From Ivanhoe.com - July 26, 2012 Category: Consumer Health News Source Type: news

Celebrating 22 Years of the ADA
On July 26, 2012, the Americans with Disabilities Act (ADA) becomes 22 years old.  The passage of the ADA 22 years ago was a watershed moment in civil rights history, as it was the first time that the law contained protections for the civil rights of deaf and hard of hearing people and other people with disabilities. read more
Source: National Association of the Deaf - July 25, 2012 Category: Audiology Authors: admin Source Type: news

Precision in defining sequelae of meningitis
Investigators in France report a cohort of infants and young children who were referred for vestibular testing because of postural instability following bacterial meningitis. Extensive vestibular tests, audiologic evaluations, neurologic examination, and brain and temporal bone imaging were performed. Of the 34 children who had a normal neurologic examination at the time of testing, 26 had partial or complete loss of vestibular function. Degree of vestibular loss was correlated highly with sensorineural hearing impairment and Streptococcus pneumoniae as the cause of meningitis. Although vestibular impairment was associated...
Source: The Journal of Pediatrics - July 25, 2012 Category: Pediatrics Authors: Sarah S. Long Tags: The Editors' Perspectives Source Type: research

Indications and outcome of subtotal petrosectomy for active middle ear implants
Abstract  The aim of this study was to describe the outcome and possible complications of subtotal petrosectomy (SP) for Vibrant Soundbridge (VSB) device surgery in a tertiary referral center. A secondary objective was the evaluation of hearing results in a subgroup of subjects who received the VSB device. Between 2009 and early 2011, 22 adult subjects with chronic otitis media (COM) underwent a SP, blind sac closure of the external auditory canal and abdominal fat obliteration to facilitate the application of an active middle ear implant (AMEI) in a staged procedure. Indications consisted of mixed hearing lo...
Source: European Archives of Oto-Rhino-Laryngology - July 25, 2012 Category: ENT & OMF Tags: European Archives of Oto-Rhino-Laryngology Source Type: research

Characteristics and application of inner ear CT in 20 cases of sensorineural hearing loss in children.
Conclusion: This study shows that a number of children with sensorineural hearing loss (SNHL) have inner ear malformations demonstrated by multi-slice spiral computed tomography (MSCT). MSCT allows a comprehensive assessment of various congenital inner ear malformations through high quality multiplanar reformation (MPR) and can display the site and degree of the malformation three-dimensionally and intuitively. This is very useful for cochlear implantation. Objective: To evaluate the feasibility and usability of MSCT in pediatric SNHL with inner ear malformations. Methods: Sixty-five patients were diagnosed with SNHL by br...
Source: Acta Oto-Laryngologica - July 25, 2012 Category: ENT & OMF Authors: Huo L, Wang H Tags: Acta Otolaryngol Source Type: research

Unilateral cochlear nerve hypoplasia in children with mild to moderate hearing loss.
Conclusion: Even if hearing loss is mild to moderate, the presence of cochlear nerve (CN) hypoplasia associated with retrocochlear disorders should be considered. Objectives: CN hypoplasia is a term that refers to an absent cochlear nerve on high-resolution magnetic resonance imaging (MRI). Most cases of CN hypoplasia are associated with profound hearing loss. The present study reports six pediatric cases of unilateral CN hypoplasia with mild to moderate hearing loss. Methods: Between May 2008 and April 2011, pure-tone hearing tests were performed in 17 patients who were diagnosed with CN hypoplasia on high resolution for ...
Source: Acta Oto-Laryngologica - July 25, 2012 Category: ENT & OMF Authors: Taiji H, Morimoto N, Matsunaga T Tags: Acta Otolaryngol Source Type: research

The prediction of CSF gusher in cochlear implants with inner ear abnormality.
Conclusion: The incidence rate of the cerebrospinal fluid (CSF) gusher in cochlear implant with inner ear abnormality is 30%. Bony defect in the fundus of the internal acoustic meatus is most often responsible for the occurrence of CSF gusher. This feature of the CT scan can be used to predict the occurrence of a CSF gusher. Objective: To predict the occurrence of CSF gusher in cochlear implants with inner ear abnormality. Methods: This was a retrospective analysis of 442 patients with inner ear abnormality who underwent cochlear implantation from February 1998 to July 2011. The patients were reviewed for the findings on t...
Source: Acta Oto-Laryngologica - July 25, 2012 Category: ENT & OMF Authors: Hongjian L, Guangke W, Song M, Xiaoli D, Daoxing Z Tags: Acta Otolaryngol Source Type: research

Immunogold TEM of otoconin 90 and otolin - relevance to mineralization of otoconia, and pathogenesis of benign positional vertigo.
Abstract Implementation of the deep-etch technique enabled unprecedented definition of substructural elements of otoconia, including the fibrillar meshwork of the inner core with its globular attachments. Subsequently the effects of the principal soluble otoconial protein, otoconin 90, upon calcite crystal growth in vitro were determined, including an increased rate of nucleation, inhibition of growth kinetics and significant morphologic changes. The logical next step, ultrastructural localization of otoconin 90, by means of immunogold TEM in young mature mice, demonstrated a high density of gold particles in the ...
Source: Hearing Research - July 25, 2012 Category: Audiology Authors: Andrade LR, Lins U, Farina M, Thalmann R Tags: Hear Res Source Type: research

Inner hair cells of mice express the glutamine transporter SAT1.
Abstract Glutamate has been implicated in signal transmission between inner hair cells and afferent fibers of the organ of Corti. The inner hair cells are enriched in glutamate and the postsynaptic membranes express AMPA glutamate receptors. However, it is not known whether inner hair cells contain a mechanism for glutamate replenishment. Such a mechanism must be in place to sustain glutamate neurotransmission. Here we provide RT-PCR and immunofluorescence data indicating that system A transporter 1, which is responsible for glutamine transport into glutamatergic neurons in brain, is expressed in inner hair cells. ...
Source: Hearing Research - July 25, 2012 Category: Audiology Authors: Oguchi T, Suzuki N, Hashimoto S, Chaudhry GA, Chaudhry FA, Usami SI, Ottersen OP Tags: Hear Res Source Type: research

Characterizing the dependence of pure-tone frequency difference limens on frequency, duration, and level.
This study examined the relationship between the difference limen for frequency (DLF) of pure tones and three commonly explored stimulus parameters of frequency, duration, and sensation level. Data from 12 published studies of pure-tone frequency discrimination (a total of 583 DLF measurements across 77 normal-hearing listeners) were analyzed using hierarchical (or "mixed-effects") generalized linear models. Model parameters were estimated using two approaches (Bayesian and maximum likelihood). A model in which log-transformed DLFs were predicted using a sum of power-law functions plus a random subject- or group-specific t...
Source: Hearing Research - July 25, 2012 Category: Audiology Authors: Micheyl C, Xiao L, Oxenham AJ Tags: Hear Res Source Type: research

Sign language aphasia from a neurodegenerative disease.
This report illustrates the challenges in evaluation of a patient for the presence of degenerative dementia when the person is deaf from birth, uses sign language, and has a late age of primary language acquisition. Although our patient could neither speak nor hear, in many respects her cognitive disorders mirror those of patients with AD who had normally learned to speak. PMID: 22823942 [PubMed - as supplied by publisher]
Source: Neurocase - July 24, 2012 Category: Neurology Authors: Falchook AD, Mayberry RI, Poizner H, Burtis DB, Doty L, Heilman KM Tags: Neurocase Source Type: research

'Out of nowhere I was deaf': How thousands are losing their hearing without warning
Chris Cooper, 54, suffered sudden sensorineural hearing loss, or sudden deafness. He had never heard of the condition before.
Source: the Mail online | Health - July 23, 2012 Category: Consumer Health News Source Type: news

Brown–Vialetto–van Laere and Fazio–Londe overlap syndromes: A clinical, biochemical and genetic study
Abstract: Brown–Vialetto–van Laere (BVVL) and Fazio–Londe (FL) are rare and clinically overlapping motor neurons syndromes. Recently BVVL has been associated with mutations in C20orf54/hRFT2 and defective riboflavin transport. We compared clinical and laboratory features of 6 patients (age range 11–17years), with features of BVVL and FL overlap syndromes. Patients were assessed as following: blood levels of riboflavin and redox status, electrophysiological, neuroradiological and pulmonary studies, ALS functional rating scale and molecular genetic analysis.Two patients manifested deafness at ages of 3 and 10years, a...
Source: Neuromuscular Disorders - July 23, 2012 Category: Neurology Authors: Marianna Ciccolella, Michela Catteruccia, Sabina Benedetti, Isabella Moroni, Graziella Uziel, Chiara Pantaleoni, Luisa Chiapparini, Alberto Bizzi, Adele D’Amico, Fabiana Fattori, Maria Letizia Salsano, Anna Pastore, Giulia Tozzi, Fiorella Piemonte, Enri Tags: Research papers Source Type: research

WDR1 expression in normal and noise‐damaged sprague‐dawley rat cochleae
AbstractWD40 repeat protein 1 (WDR1) has been suggested as a protective mechanism or a sign of regeneration in avian cochlea. However, its role in mammalian cochlea has yet to be determined. Hence we investigated WDR1 expression in sound‐overstimulated Sprague‐Dawley rats. Rats were divided into 3 groups [the permanent‐ and temporary threshold shift (PTS and TTS) groups and the control group], according to the extent of noise exposure and euthanized immediately, 3‐ or 7 days after noise exposure for cochlear harvest. Immunocytochemistry localized WDR1 to outer hair cells, Deiter's cells, outer sulcus cells and Reis...
Source: The Journal of Comparative Neurology - July 23, 2012 Category: Neurology Authors: Jae‐Jin Song, Henry J. Adler, Ho Sun Lee, Jeong Hun Jang, Min‐Hyun Park, Jun Ho Lee, Sun O Chang, Seung Ha Oh Tags: Research Article Source Type: research

[Allgrove syndrome (triple A). Finding of a mutation not described in the AAAS gene.]
We report a case of a 19 year-old male, assessed when he was 10 years old in our department due to suspected storage disease. Mild mental and language retardation, hypernasal voice, sensory-motor neuropathy with autonomic involvement and signs of spastic paraparesis, alacrimia. gastroesophageal reflux, and achalasia. Molecular studies showed to mutations, the undescribed p.Tyr 19 Cys, and IVS14 +1 G. PMID: 22824007 [PubMed - as supplied by publisher]
Source: Anales de Pediatria - July 21, 2012 Category: Pediatrics Authors: Capataz Ledesma M, Méndez Pérez P, Rodríguez López R, Galán Gómez E Tags: An Pediatr (Barc) Source Type: research

The auditory hair cell ribbon synapse: from assembly to function.
Abstract Cochlear inner hair cells (IHCs), the mammalian auditory sensory cells, encode acoustic signals with high fidelity by Graded variations of their membrane potential trigger rapid and sustained vesicle exocytosis at their ribbon synapses. The kinetics of glutamate release allows proper transfer of sound information to the primary afferent auditory neurons. Understanding the physiological properties and underlying molecular mechanisms of the IHC synaptic machinery, and especially its high temporal acuity, which is pivotal to speech perception, is a central issue of auditory science. During the past decade, su...
Source: Annual Review of Neuroscience - July 21, 2012 Category: Neurology Authors: Safieddine S, El-Amraoui A, Petit C Tags: Annu Rev Neurosci Source Type: research

The Incidence of Depression and Its Risk Factors in Dutch Nursing Homes and Residential Care Homes.
CONCLUSIONS:: The incidence rate for depression in residents of Dutch nursing homes and residential care homes was high and the associated risk factors found may have important implications for staff. PMID: 22828203 [PubMed - as supplied by publisher]
Source: Am J Geriatr Psychia... - July 21, 2012 Category: Geriatrics Authors: Boorsma M, Joling K, Dussel M, Ribbe M, Frijters D, van Marwijk HW, Nijpels G, van Hout H Tags: Am J Geriatr Psychiatry Source Type: research

Hearing Aid Types and Bluetooth Electronics
People who experience a loss of hearing might be considering obtaining hearing aids, yet are concerned about how they will look. They may wonder if a hearing aid will truly help them. Knowing more about the options related to hearing aids that are available can help, such as what to look for when purchasing hearing aids and how they may interact with electronics, easing some concerns.
Source: Disabled World - July 20, 2012 Category: Disability Tags: Assistive Hearing Devices Source Type: news

Deafness: from suspicion to referral for intervention
CONCLUSIONS: The qualification and attention of health professionals is important to enable the early diagnosis of deafness, allowing appropriate support for the family and patients' referral and follow-up.OBJETIVO: Investigar la vivencia de las madres entre la sospecha, el diagnóstico de sordera y el encaminamiento para habilitación, así como la percepción de ellas respecto a la forma como se dio y explicó el diagnóstico. MÉTODOS: Estudio cualitativo con diez madres oyentes con hijos sordos que frecuentaban atención especializada en Centro de Estudios e Investigaciones en Rehabilitación, en la provincia de São P...
Source: Revista Paulista de Pediatria - July 20, 2012 Category: Pediatrics Source Type: research

ACTION ALERT: Support Deaf and Hard of Hearing Truck Drivers
Deaf and hard of hearing truck drivers need your support! We need your help to tell the U.S. Department of Transportation that deaf and hard of hearing people should be permitted to drive trucks! read more
Source: National Association of the Deaf - July 20, 2012 Category: Audiology Authors: admin Source Type: news

Differences in parvalbumin and calbindin chemospecificity in the centers of the turtle ascending auditory pathway revealed by double immunofluorescence labeling.
Abstract Using double immunofluorescence labeling, quantitative ratio between parvalbumin- and calbindin-containing neurons, neurons that co-localize both peptides, as well as the intensity of their immunoreactivities were studied in the brainstem, midbrain and forebrain auditory centers of two chelonian species, Testudo horsfieldi and Emys orbicularis. In the spiral ganglion and first-order cochlear nuclei, highly immunoreactive parvalbumin-containing neurons predominated, and almost all neurons in these nuclei also exhibited weak immunoreactivity to calbindin. The number of strongly calbindin-immunoreactive (-ir)...
Source: Brain Research - July 20, 2012 Category: Neurology Authors: Chudinova TV, Belekhova MG, Tostivint H, Ward R, Rio JP, Kenigfest NB Tags: Brain Res Source Type: research

Protein phosphatase‐1M and Rho‐kinase affect exocytosis from cortical synaptosomes and influence neurotransmission at a glutamatergic giant synapse of the rat auditory system
AbstractProtein phosphatase‐1M (PP1M, myosin phosphatase) consists of a PP1 catalytic subunit (PP1c) and the myosin phosphatase target subunit‐1 (MYPT1). RhoA‐activated kinase (ROK) regulates PP1M via inhibitory phosphorylation of MYPT1. Using multidisciplinary approaches, we have studied the roles of PP1M and ROK in neurotransmission. Electron microscopy demonstrated the presence of MYPT1 and ROK in both pre‐ and postsynaptic terminals. Tautomycetin (TMC), a PP1‐specific inhibitor, decreased the depolarization‐induced exocytosis from cortical synaptosomes. Y27632, a ROK‐specific inhibitor, had the opposite e...
Source: Journal of Neurochemistry - July 20, 2012 Category: Neurology Authors: Beáta Lontay, Balázs Pál, Zoltán Serfőző, Áron Kőszeghy, Géza Szücs, Zoltán Rusznák, Ferenc Erdődi Source Type: research

Your Input Needed: NAD Captioning Survey!
The National Association of the Deaf needs your input about captioning! Your responses will help to guide our position when we discuss captioning with the industry. Remember, your feedback is very important. The only way we'll know what is important to you is if you tell us now! Fill out our Captioning Survey here.  read more
Source: National Association of the Deaf - July 19, 2012 Category: Audiology Authors: admin Source Type: news

Tell us what you think about #NAD12!
Now's your chance to tell us all about the 2012 NAD Conference in Louisville, and what we can do to make our next NAD Conference the best ever! Want to see more NAD apparel, books, or buy a "Nothing About Us, Without Us" T-shirt? Love a workshop or a presenter? Not crazy about the Louisville temperatures? Well, you can let us know what you want to see at our next NAD Conference! Fill out our NAD Conference Survey NOW and tell us about your NAD Conference experience, and what you'd like to see happen in Atlanta in 2014! read more
Source: National Association of the Deaf - July 18, 2012 Category: Audiology Authors: NAD Conference Tags: NAD Conference Source Type: news

URGENT: Support the Ratification of the Convention on the Rights of Persons with Disabilities TODAY!
UPDATE from our friends at USICD: The CRPD markup and vote in the Senate Foreign Relations Committee has been rescheduled for the ADA Anniversary date: Thursday, July 26th at 9:30 AM at the Dirksen Senate Office Building, G-50 on Capitol Hill. We need the room filled with advocates on Thursday, July 26th! read more
Source: National Association of the Deaf - July 18, 2012 Category: Audiology Authors: admin Source Type: news

Evaluation of round window accessibility to cochlear implant insertion
The objectives of this study were: (1) to prospectively evaluate the STH classification in selecting the appropriate cochlear insertion route in “RWM-intentioned” cases, and (2) to ascertain if RWM accessibility differs from adults to children. This was a prospective cohort study of consecutive patients (adult and paediatric) undergoing cochlear implantation at a specialist auditory implant centre. Visibility of the RWM was graded according to the STH classification after an “optimal” posterior tympanotomy had been performed and any overhang of the bony round window niche removed without breaching the RWM. Most...
Source: European Archives of Oto-Rhino-Laryngology - July 18, 2012 Category: ENT & OMF Tags: European Archives of Oto-Rhino-Laryngology Source Type: research

Metabolic disorders: Lipids go deaf
Nature Chemical Biology 8, 678 (2012). doi:10.1038/nchembio.1034 Author: Mirella Bucci
Source: Nature Chemical Biology - July 18, 2012 Category: Biology Authors: Mirella Bucci Tags: Research Highlights Source Type: research

The Effect of Superior Semicircular Canal Dehiscence on Intracochlear Sound Pressures
Audiol Neurotol 2012;17:338–348 (DOI:10.1159/000339653)
Source: Audiology and Neurotology - July 17, 2012 Category: Audiology Source Type: research

Hearing Preservation after Cochlear Implantation Using Deeply Inserted Flex Atraumatic Electrode Arrays
Audiol Neurotol 2012;17:331–337 (DOI:10.1159/000339894)
Source: Audiology and Neurotology - July 17, 2012 Category: Audiology Source Type: research

Clinical Trial Results with the MED-EL Fine Structure Processing Coding Strategy in Experienced Cochlear Implant Users
ORL 2012;74:185–198 (DOI:10.1159/000337089)
Source: ORL - July 17, 2012 Category: ENT & OMF Source Type: research

NLM Informationist Supplement Grants Awarded
Nineteen applications were received in response to NLM’s  Administrative Supplement for Informationist Services. The supplement provides up to $50,000 for 2 years to an active NIH-funded researcher, in order to bring needed information expertise into the research team. Applications were received from principal investigators currently funded by six NIH institutes: Aging, Cancer, Dental, Deafness, Eye and NLM.  Seven NIH researchers will receive Informationist supplement awards. All of the projects selected to receive awards bring librarian informationists into research settings and measure the value of their contrib...
Source: Midcontinental Region News - July 17, 2012 Category: Databases & Libraries Authors: liaison Tags: All Members Source Type: news

First Vlog from the New President of the NAD, Chris Wagner!
We proudly introduce the first vlog of Chris Wagner, the new President of the National Association of the Deaf! Watch President Wagner now, and learn more about his plans for the future of the NAD. President Wagner was just elected at the 51st Biennial NAD Conference in Louisville, Kentucky.   read more
Source: National Association of the Deaf - July 17, 2012 Category: Audiology Authors: admin Source Type: news