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This page shows you the 20 most read items in the past 30 days within this specialty in the MedWorm directory.

Interaction of [alpha]-gliadin with polyanions: Design considerations for sequestrants used in supportive treatment of celiac diseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This study provides insight into design considerations for polymer sequestrants used in the supportive treatment of celiac disease. © 2009 Wiley Periodicals, Inc. Biopolymers, 2009 (Source: Biopolymers)
Source: Biopolymers - November 18, 2009 Category: Biochemistry Authors: Li Liang, Maud Pinier, Jean-Christophe Leroux, Muriel Subirade Source Type: journals

Tryptophan Synthase: Structure and Function of the Monovalent Cation SiteEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Biochemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Biochemistry)
Source: Biochemistry - October 30, 2009 Category: Biochemistry Tags: article Source Type: journals

Matrix elasticity regulates the secretory profile of human bone marrow-derived multipotent mesenchymal stromal cells (MSCs).Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The therapeutic efficacy of multipotent mesenchymal stromal cells (MSCs) is attributed to particular MSC-derived cytokines and growth factors. As MSCs are applied locally to target organs or home there after systemic administration, they experience diverse microenvironments that are biochemically and biophysically distinct. Here we use well-defined in vitro conditions to study the impact of substrate elasticity on MSC-derived trophic factors. By varying hydrogel compliance, the elasticity of brain and muscle tissue was mimicked. We screened >90 secreted factors at the protein level, finding a diverse elasticity-depe...
Source: Biochemical and Biophysical Research communications - November 3, 2009 Category: Biochemistry Authors: Seib FP, Prewitz M, Werner C, Bornhäuser M Tags: Biochem Biophys Res Commun Source Type: journals

Critical Role of Tryptophan 154 for the Activity and Stability of Class D β-LactamasesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Biochemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Biochemistry)
Source: Biochemistry - November 5, 2009 Category: Biochemistry Tags: article Source Type: journals

Metabonomics in Ulcerative Colitis: Diagnostics, Biomarker Identification, And Insight into the PathophysiologyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Journal of Proteome Research, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Proteome Research)
Source: Journal of Proteome Research - November 20, 2009 Category: Biochemistry Tags: article Source Type: journals

Two-Dimensional Difference Gel Electrophoresis (DiGE) Analysis of Plasmas from Dengue Fever PatientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Journal of Proteome Research, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Proteome Research)
Source: Journal of Proteome Research - November 9, 2009 Category: Biochemistry Tags: article Source Type: journals

Multiorigination of Chromatographic Peaks in Derivatized GC/MS Metabolomics: A Confounder That Influences Metabolic Pathway InterpretationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Journal of Proteome Research, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Proteome Research)
Source: Journal of Proteome Research - October 31, 2009 Category: Biochemistry Tags: article Source Type: journals

Cytokines and Cytokine Profiles in Human Autoimmune Diseases and Animal Models of AutoimmunityEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The precise pathomechanisms of human autoimmune diseases are still poorly understood. However, a deepened understanding of these is urgently needed to improve disease prevention and early detection and guide more specific treatment approaches. In recent years, many new genes and signalling pathways involved in autoimmunity with often overlapping patterns between different disease entities have been detected. Major contributions were made by experiments using DNA microarray technology, which has been used for the analysis of gene expression patterns in chronic inflammatory and autoimmune diseases, among which were rheumatoi...
Source: Mediators of Inflammation - October 26, 2009 Category: Biochemistry Source Type: journals

Cloning and characterization of the 5'UTR of the rat anti-apoptotic Bcl-w gene.Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The anti-apoptotic Bcl-w regulator, which is expressed in the developing and mature brain, not only promotes neuronal survival, but also neuronal differentiation. However, its transcriptional regulation remains to be elucidated due to a lack of knowledge of the Bcl-w promoter. Here, we report the mapping and characterization of the rat Bcl-w promoter, which is highly conserved between the human, mouse, and rat species. Using a series of 5' and 3' deletions, we mapped the TATA-less minimal Bcl-w promoter and showed that it is under a combinatorial regulation with the neurogenic bHLH transcription factor NeuroD6 mediatin...
Source: Biochemical and Biophysical Research communications - November 3, 2009 Category: Biochemistry Authors: Uittenbogaard M, Baxter KK, Chiaramello A Tags: Biochem Biophys Res Commun Source Type: journals

Enzymatic and mRNA Transcript Response of Ovine 6-Phosphogluconate Dehydrogenase (6PGD) in Respect to Different Milk YieldEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Ovine 6-phosphogluconate dehydrogenase (6PGD) is an enzyme of the pentose phosphate pathway, providing the necessary compounds of NADPH for the synthesis of fatty acids. Much of research has been conducted both on enzymatic level and on molecular level. However, to our knowledge, any correlation between enzymatic activity and 6PGD gene expression pattern related to different physiological stages has not been yet reported. With this report, we tried to highlight if any correlation between enzymatic activity and expression of ovine 6PGD gene exists, in respect to different milk yield. According to the determined enzymatic ac...
Source: Research Letters in Biochemistry - November 16, 2009 Category: Biochemistry Source Type: journals

Improving diffraction by humidity control: a novel device compatible with X-ray beamlinesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Dehydration of protein crystals is rarely used, despite being a post-crystallization method that is useful for the improvement of crystal diffraction properties, as it is difficult to reproduce and monitor. A novel device for hydration control of macromolecular crystals in a standard data-collection environment has been developed. The device delivers an air stream of precise relative humidity that can be used to alter the amount of water in macromolecular crystals. The device can be rapidly installed and is fully compatible with most standard synchrotron X-ray beamlines. Samples are mounted in cryoloops and the progress of...
Source: Acta Crystallographica Section D - November 18, 2009 Category: Biochemistry Authors: Sanchez-Weatherby, J.Bowler, M.W.Huet, J.Gobbo, A.Felisaz, F.Lavault, B.Moya, R.Kadlec, J.Ravelli, R.B.G.Cipriani, F. Tags: humidity-control device X-ray diffraction improvement crystallographic synchrotron instrumentation crystal dehydration research papers Source Type: journals

Th17: A New Participant in Gut Dysfunction in Mice Infected with Trichinella spiralisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Trichinella spiralis infection in rodents is a well-known model of intestinal inflammation associated with hypermotility. Our aim was to elucidate if Th17 cells were involved in the development of gastrointestinal hypermotility in this experimental model. Intestinal inflammation was observed by hematoxylin-eosin (HE) staining. Jejunal smooth muscle contractility was investigated in response to acetylcholine (Ach). The effects of IL-17 on jejunum smooth muscle contractility were explored. Flow cytometry was used to analyze the proportion of Th17 cells in jejunum. The levels of IL-17, IL-23, and TGF-β1 in jejunum were...
Source: Mediators of Inflammation - November 18, 2009 Category: Biochemistry Source Type: journals

Correlation of Plasma MMP-1 and TIMP-1 Levels and the Colonic Mucosa Expressions in Patients with Ulcerative ColitisEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion. Plasma MMP-1 and TIMP-1 levels reflect their colonic mucosal expression to some extent in patients with UC. Plasma MMP-1 and TIMP-1, in particular, demonstrate the potential to become biomarkers to clinically diagnose UC, predict its severity, and guide further therapy. (Source: Mediators of Inflammation)
Source: Mediators of Inflammation - November 9, 2009 Category: Biochemistry Source Type: journals

Ceramide Kinase Profiling by Mass Spectrometry Reveals a Conserved Phosphorylation Pattern Downstream of the Catalytic SiteEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Journal of Proteome Research, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Proteome Research)
Source: Journal of Proteome Research - November 20, 2009 Category: Biochemistry Tags: article Source Type: journals

The Red Blood Cell Proteome and Interactome: An UpdateEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Journal of Proteome Research, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Proteome Research)
Source: Journal of Proteome Research - November 20, 2009 Category: Biochemistry Tags: article Source Type: journals

Direct One-Step18F-Labeling of Peptides via Nucleophilic Aromatic SubstitutionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Bioconjugate Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Bioconjugate Chemistry)
Source: Bioconjugate Chemistry - November 18, 2009 Category: Biochemistry Tags: article Source Type: journals

Protection of Salvia miltiorrhizae to the Spleen and Thymus of Rats with Severe Acute Pancreatitis or Obstructive JaundiceEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusion. Salvia miltiorrhizae exerts protective effects on the spleen and thymus of SAP rats and spleen of OJ rats. (Source: Mediators of Inflammation)
Source: Mediators of Inflammation - November 16, 2009 Category: Biochemistry Source Type: journals

Gene Mutation Alone Causes Transmissible Prion DiseaseEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
For the first time, Whitehead Institute researchers have shown definitively that mutations associated with prion diseases are sufficient to cause a transmissible neurodegenerative disease. The discovery is reported in the August 27 edition of the journal Neuron. Until now, two theories about the role mutations play in prion diseases have been at odds. According to one theory, mutations make carriers more susceptible to prions in the environment. (Source: Biology / Biochemistry News From Medical News Today)
Source: Biology / Biochemistry News From Medical News Today - August 27, 2009 Category: Biochemistry Tags: CJD / vCJD / Mad Cow Disease Source Type: news

Why Younger People Are More At Risk Of vCJDEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Specific cells within the immune system could help explain why younger people are more susceptible to variant CJD, scientists believe. Patients diagnosed with variant CJD are, on average, 28 years old but it has been unclear why older people are not as affected by the disease. (Source: Biology / Biochemistry News From Medical News Today)
Source: Biology / Biochemistry News From Medical News Today - October 15, 2009 Category: Biochemistry Tags: CJD / vCJD / Mad Cow Disease Source Type: news

Research Into Fungal Self-Fertilisation Could Lead To Disease Prevention, Pharmaceuticals And Food ProductsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Research from The University of Nottingham sheds new light on a fascinating phenomenon of the natural world -- the ability of some species to reproduce sexually without a partner.Scientists have been trying to determine how individuals of a key fungus, Aspergillus nidulans, are able to have sex without the need for a partner. [click link for full article] (Source: Biology / Biochemistry News From Medical News Today)
Source: Biology / Biochemistry News From Medical News Today - August 19, 2007 Category: Biochemistry Source Type: news