Biology
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Calendar of Events – January 2010
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(Source: Chemical Biology and Drug Design)
Source: Chemical Biology and Drug Design - November 21, 2009 Category: Biology Source Type: journals
Just like old times: Generating RNA molecules in water
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(American Society for Biochemistry and Molecular Biology) A key question in the origin of biological molecules like RNA and DNA is how they first came together billions of years ago from simple precursors. Now, in a study appearing in this week's JBC, researchers in Italy have reconstructed one of the earliest evolutionary steps yet: generating long chains of RNA from individual subunits using nothing but warm water. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - November 20, 2009 Category: Biology Source Type: news
NSF awards $7.5M grant to University of Oklahoma for plant genomics
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(University of Oklahoma) A decade ago, a group of University of Oklahoma researchers were sequencing the first human chromosome as part of the human genome project. Today, the OU Advanced Center for Genome Technology is contributing to an international effort to sequence the tomato genome with a $7.5 million grant awarded by the National Science Foundation for plant genomics. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - November 20, 2009 Category: Biology Source Type: news
International expedition investigates climate change, alternative fuels in Arctic
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(Naval Research Laboratory) NRL marine biogeochemistry and geology and geophysics scientists return from Arctic expedition exploring methane hydrate deposits in the Beaufort Sea and spatial variation of sediment contribution to Arctic climate change. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - November 20, 2009 Category: Biology Source Type: news
NJIT receives NSF funding to improve Big Bear Telescope, study solar energy
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(New Jersey Institute of Technology) The National Science Foundation has recently provided support that totals nearly $4.3 million for the diverse efforts of the following investigators under the American Recovery and Reinvestment Act of 2009. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - November 20, 2009 Category: Biology Source Type: news
It's a gas: New discovery may lead to heartier, high-yielding plants
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(Genetics Society of America) In a research report in the November 2009 journal Genetics, scientists show how a family of genes (1-aminocyclopropane-1-carboxylate synthase, or ACS genes), in the weed Arabidopsis thaliana, are responsible for production of ethylene. This gas affects many aspects of plant development, and this information, which will be applicable to other plants, lays the foundation for future genetic manipulation that could make plants disease resistant, able to survive and thrive in difficult terrain, and increase yields. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - November 20, 2009 Category: Biology Source Type: news
Delft breakthrough in bioethanol production from agricultural waste
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(Delft University of Technology) With the introduction of a single bacterial gene into yeast, researchers from Delft University of Technology in the Netherlands achieved three improvements in bioethanol production from agricultural waste material: "More ethanol, less acetate and elimination of the major by-product glycerol." This week the invention was published in the scientific journal Applied and Environmental Microbiology. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - November 20, 2009 Category: Biology Source Type: news
Biologists discover bacterial defense mechanism against aggressive oxygen
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(VIB (the Flanders Institute for Biotechnology)) Bacteria possess an ingenious mechanism for preventing oxygen from harming the building blocks of the cell. This is the new finding of a team of biologists that includes Joris Messens of VIB, a life sciences research institute in Flanders, Belgium, connected to the Vrije Universiteit Brussel. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - November 20, 2009 Category: Biology Source Type: news
Flax and yellow flowers can produce bioethanol
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(FECYT - Spanish Foundation for Science and Technology) Surplus biomass from the production of flax sheaves, and generated from Brassica carinata, a yellow-flowered plant related to those which engulf fields in spring, can be used to produce bioethanol. This has been suggested by two studies carried out by Spanish and Dutch researchers and published in the journal Renewable and Sustainable Energy Reviews. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - November 20, 2009 Category: Biology Source Type: news
Lehigh receives grant to reduce cost of carbon capture at coal-fired power plants
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(Lehigh University) A US Department of Energy grant will help develop methods of recovering and reusing heat generated by the compression of CO2 in a carbon-capture system. The goal is to facilitate carbon capture and sequestration and limit the amount of CO2 emitted into the atmosphere by coal-fired power plants. Unlike other modeling studies, which focus on specific components of the carbon-capture system, the Lehigh researchers will look at the entire power plant. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - November 20, 2009 Category: Biology Source Type: news
Carvedilol shown to have unique characteristics among beta blockers
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(University of Illinois at Urbana-Champaign) In a new study, researchers report that a class of heart medications called beta-blockers can have a helpful, or harmful, effect on the heart, depending on their molecular activity. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - November 20, 2009 Category: Biology Source Type: news
CB&DD Senior Editor Team
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(Source: Chemical Biology and Drug Design)
Source: Chemical Biology and Drug Design - November 20, 2009 Category: Biology Source Type: journals
Computational Model of Membrane Fission Catalyzed by ESCRT-III
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Author Summary
Membrane fission is a key step of fundamental intracellular processes such as endocytosis, membrane trafficking, cytokinesis and virus budding. The fission reaction requires substantial energy inputs provided by specialized proteins. Recently, the ESCRT-III proteins have been implicated in membrane budding and fission involved in multivesicular body formation, cytokinesis and virus budding. The ESCRT-III proteins self-assemble into circular filaments and flat spirals in the membrane plane and generate tubular structures with dome-like end caps. We suggest and elaborate computationally on a mechanism by whic...
Source: PLoS Computational Biology - November 20, 2009 Category: Biology Authors: Gur Fabrikant et al. Source Type: journals
Dynamic Allostery in the Methionine Repressor Revealed by Force Distribution Analysis
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Author Summary
Proteins carry out most of the cellular processes, from metabolic reactions to the regulation and expression of genes. Tight and effective regulation of the executing protein machinery is commonly achieved by allostery. The only general requirement for allosteric communication is the transmission of a signal, e.g., the binding of a cofactor, from the ligand binding site to the allosteric (active) protein site; in other words an internal propagation of strain. Based on molecular dynamics simulations, we recently presented a method that allows visualization of force distribution in proteins. We here applied t...
Source: PLoS Computational Biology - November 20, 2009 Category: Biology Authors: Wolfram Stacklies et al. Source Type: journals
Evaluation of the Oscillatory Interference Model of Grid Cell Firing through Analysis and Measured Period Variance of Some Biological Oscillators
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Author Summary
For many animals, including rats, accurate spatial memory over relatively large areas is important in order to find food and shelter. Just as unique points in time can be efficiently represented by combinations of repeating elements like hours, days, and months, points in space can be represented as combinations of elements that repeat at different spatial scales. Just such a code has been identified in the brains of rats and it shows an intriguing triangular spacing of encoded locations. Two different explanations have been developed as to what general mechanism in the brain might be able to generate this ...
Source: PLoS Computational Biology - November 20, 2009 Category: Biology Authors: Eric A. Zilli et al. Source Type: journals
Stochastic Drift in Mitochondrial DNA Point Mutations: A Novel Perspective Ex Silico
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Author Summary
Aging is characterized by a systemic decline of an organism's capacity in responding to internal and external stresses, leading to increased mortality. The mitochondrial Free Radical Theory of Aging (mFRTA) attributes this decline to the accumulation of damages, in the form of mitochondrial DNA (mtDNA) mutations, caused by free radical byproducts of metabolism. However, there is still a great deal of uncertainty with this theory due to the difficulties in quantifying mtDNA mutation burden. In this modeling study, we have shown that a random drift in mtDNA point mutation during life, in combination with the ...
Source: PLoS Computational Biology - November 20, 2009 Category: Biology Authors: Suresh Kumar Poovathingal et al. Source Type: journals
Exon Array Analysis of Head and Neck Cancers Identifies a Hypoxia Related Splice Variant of LAMA3 Associated with a Poor Prognosis
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Alternative splicing is the process by which cells express a set of different, but related, transcripts from a single gene. When translated, each transcript results in a different protein, resulting in additional cellular complexity. Affymetrix Exon microarrays, which feature multiple probesets targeting different locations throughout each gene, allow the changes in transcription that result from alternative splicing to be investigated in a single genome-wide assay. In addition, the increased number of probesets targeting each gene offers the potential to combine signals in order to increase statistical pow...
Source: PLoS Computational Biology - November 20, 2009 Category: Biology Authors: Carla S. Moller-Levet et al. Source Type: journals
A Novel Extended Granger Causal Model Approach Demonstrates Brain Hemispheric Differences during Face Recognition Learning
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The right temporal cortex has previously been shown to play a greater role in the discrimination of faces in both sheep and humans. In the frequency domain, analysis of the relative causal contributions of low (theta 4–8Hz) and high (gamma 30–70Hz) frequency oscillations reveals that prior to learning, theta activity is more predominant in right than in left hemisphere processing, and that learning reduces this so that high frequency oscillations gain more control. We have been able to demonstrate that the frequency of connections increases in the right hemisphere and decreases between the left and righ...
Source: PLoS Computational Biology - November 20, 2009 Category: Biology Authors: Tian Ge et al. Source Type: journals
Spatial Analysis of Expression Patterns Predicts Genetic Interactions at the Mid-Hindbrain Boundary
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Understanding brain formation during development is a tantalizing challenge. It is also essential for the fight against neurodegenerative diseases. In vertebrates, the central nervous system arises from a structure called the neural plate. This tissue is divided into four regions, which continue to develop into forebrain, midbrain, hindbrain and spinal cord. Interactions between locally expressed genes and signaling molecules are responsible for this patterning. Two key signaling molecules in this process are Fgf8 and Wnt1 proteins. They are secreted from a signaling center located at the boundary between p...
Source: PLoS Computational Biology - November 20, 2009 Category: Biology Authors: Dominik M. Wittmann et al. Source Type: journals
Circadian KaiC Phosphorylation: A Multi-Layer Network
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Circadian clocks are endogenous timing mechanisms that allow living organisms to coordinate their activities with daily environmental fluctuations. In cyanobacteria, almost all the genes are rhythmically expressed with the same ~24 h period yet exhibit a variety of phase relationships and waveforms. Remarkably, the core pacemaker ticks robustly via simple biochemical reactions carried out by three Kai proteins: KaiC undergoes circadian phosphorylation in the presence of KaiA, KaiB and ATP. In this work, we propose a reaction network modeling the Kai oscillator based on the differentiation of dual phosphoryl...
Source: PLoS Computational Biology - November 20, 2009 Category: Biology Authors: Congxin Li et al. Source Type: journals
Genome-wide analysis of major intrinsic proteins in the tree plant Populus trichocarpa: Characterization of XIP subfamily of aquaporins from evolutionary perspective
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Conclusions:
Due to whole genome duplication, Populus has the largest number of MIPs identified in any single species. Non-XIP MIPs are similar in all four plant species considered in this study. Small and weakly polar residues at the helix-helix interface are group conserved presumably to maintain the hourglass fold of MIP channels. Substitutions in ar/R selectivity filter, insertion/deletion in loop C, increasing basic nature of loop D and loss of introns are some of the events occurred during the evolution of dicot XIPs. (Source: BMC Plant Biology - Latest articles)
Source: BMC Plant Biology - Latest articles - November 20, 2009 Category: Biology Authors: Anjali GuptaRamasubbu Sankararamakrishnan Source Type: journals
Environmentally-acquired bacteria influence microbial diversity and natural innate immune responses at gut surfaces
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Conclusions:
Early-life environment significantly affects both microbial composition of the adult gut and mucosal innate immune function. We observed that a microbiota dominated by lactobacilli may function to maintain mucosal immune homeostasis and limit pathogen colonization. (Source: BMC Biology - Latest articles)
Source: BMC Biology - Latest articles - November 20, 2009 Category: Biology Authors: Imke MulderBettina SchmidtChristopher StokesMarie LewisMick BaileyRustam AminovJames ProsserBhupinder GillJohn PluskeClaus-Dieter MayerCorran MuskDenise Kelly Source Type: journals
Announcements
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The Quarterly Review of Biology, Volume 84, Issue 4, Page 331, December 2009. (Source: QRB Latest Issue)
Source: QRB Latest Issue - November 19, 2009 Category: Biology Tags: article Source Type: journals
The Bentley Glass Memorial Endowment Fund
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The Quarterly Review of Biology, Volume 84, Issue 4, Page 332, December 2009. (Source: QRB Latest Issue)
Source: QRB Latest Issue - November 19, 2009 Category: Biology Tags: article Source Type: journals
Book Review: The Fading Identity of the Developing Organism
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The Quarterly Review of Biology, Volume 84, Issue 4, Page 391-395, December 2009. (Source: QRB Latest Issue)
Source: QRB Latest Issue - November 19, 2009 Category: Biology Tags: book review New Biological Books Source Type: journals
Book Review: Structure and Dynamics of Membranous Interfaces
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The Quarterly Review of Biology, Volume 84, Issue 4, Page 417, December 2009. (Source: QRB Latest Issue)
Source: QRB Latest Issue - November 19, 2009 Category: Biology Tags: book review New Biological Books Source Type: journals
Book Review: Owen's Ape and Darwin's Bulldog: Beyond Darwinism and Creationism
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The Quarterly Review of Biology, Volume 84, Issue 4, Page 396, December 2009. (Source: QRB Latest Issue)
Source: QRB Latest Issue - November 19, 2009 Category: Biology Tags: book review New Biological Books Source Type: journals
Book Review: Single Molecule Dynamics in Life Science
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The Quarterly Review of Biology, Volume 84, Issue 4, Page 416-417, December 2009. (Source: QRB Latest Issue)
Source: QRB Latest Issue - November 19, 2009 Category: Biology Tags: book review New Biological Books Source Type: journals
Book Review: Darwin's Gift to Science and Religion
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The Quarterly Review of Biology, Volume 84, Issue 4, Page 396-397, December 2009. (Source: QRB Latest Issue)
Source: QRB Latest Issue - November 19, 2009 Category: Biology Tags: book review New Biological Books Source Type: journals
Book Review: Mechanisms of Exocytosis
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The Quarterly Review of Biology, Volume 84, Issue 4, Page 418, December 2009. (Source: QRB Latest Issue)
Source: QRB Latest Issue - November 19, 2009 Category: Biology Tags: book review New Biological Books Source Type: journals
Book Review: Reframing Scopes: Journalists, Scientists, and Lost Photographs from the Trial of the Century
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The Quarterly Review of Biology, Volume 84, Issue 4, Page 397-398, December 2009. (Source: QRB Latest Issue)
Source: QRB Latest Issue - November 19, 2009 Category: Biology Tags: book review New Biological Books Source Type: journals
Book Review: Molecular Recognition and Polymers: Control of Polymer Structure and Self‐Assembly
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The Quarterly Review of Biology, Volume 84, Issue 4, Page 417-418, December 2009. (Source: QRB Latest Issue)
Source: QRB Latest Issue - November 19, 2009 Category: Biology Tags: book review New Biological Books Source Type: journals
Medicine, Evolution, and Natural Selection: An Historical Overview
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The Quarterly Review of Biology, Volume 84, Issue 4, Page 333-355, December 2009.
ABSTRACT Contemporary Darwinian medicine is a still‐expanding new discipline, one of whose principal aims is to arrive at an evolutionary understanding of those aspects of the body that leave it vulnerable to disease. Historically, there was a precedent for this research; between 1880 and 1940, several scientists tried to develop some general evolutionary theories of disease as arising from deleterious traits that escape elimination by natural selection. In contrast, contemporary Darwinian medicine uses evolutionary theory to consider...
Source: QRB Latest Issue - November 19, 2009 Category: Biology Tags: article Source Type: journals
The Reticulating Phylogeny of Island Biogeography Theory
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The Quarterly Review of Biology, Volume 84, Issue 4, Page 357-390, December 2009.
ABSTRACT Biogeographers study all patterns in the geographic variation of life, from the spatial variation in genetic and physiological characteristics of cells and individuals, to the diversity and dynamics of biological communities among continental biotas or across oceanic archipelagoes. The field of island biogeography, in particular, has provided some genuinely transformative insights for the biological sciences, especially ecology and evolutionary biology. Our purpose here is to review the historical development of island biogeogr...
Source: QRB Latest Issue - November 19, 2009 Category: Biology Tags: article Source Type: journals
Book Review: Incredible Anaerobes: From Physiology to Genomics to Fuels
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The Quarterly Review of Biology, Volume 84, Issue 4, Page 419-420, December 2009. (Source: QRB Latest Issue)
Source: QRB Latest Issue - November 19, 2009 Category: Biology Tags: book review New Biological Books Source Type: journals
Book Review: The Marie Selby Botanical Gardens Illustrated Dictionary of Orchid Genera
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The Quarterly Review of Biology, Volume 84, Issue 4, Page 421, December 2009. (Source: QRB Latest Issue)
Source: QRB Latest Issue - November 19, 2009 Category: Biology Tags: book review New Biological Books Source Type: journals
Book Review: Photosynthetic Protein Complexes: A Structural Approach
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The Quarterly Review of Biology, Volume 84, Issue 4, Page 419, December 2009. (Source: QRB Latest Issue)
Source: QRB Latest Issue - November 19, 2009 Category: Biology Tags: book review New Biological Books Source Type: journals
Book Review: Aptamers in Bioanalysis
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The Quarterly Review of Biology, Volume 84, Issue 4, Page 418-419, December 2009. (Source: QRB Latest Issue)
Source: QRB Latest Issue - November 19, 2009 Category: Biology Tags: book review New Biological Books Source Type: journals
Book Review: Field Guide to Tidal Wetland Plants of the Northeastern United States and Neighboring Canada: Vegetation of Beaches, Tidal Flats, Rocky Shores, Marshes, Swamps, and Coastal Ponds
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The Quarterly Review of Biology, Volume 84, Issue 4, Page 420-421, December 2009. (Source: QRB Latest Issue)
Source: QRB Latest Issue - November 19, 2009 Category: Biology Tags: book review New Biological Books Source Type: journals
Index to Titles and Authors/Editors of Books Reviewed Volume 84 (2009)
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The Quarterly Review of Biology, Volume 84, Issue 4, Page 433-446, December 2009. (Source: QRB Latest Issue)
Source: QRB Latest Issue - November 19, 2009 Category: Biology Tags: article Source Type: journals
Book Review: Plant Anatomy: An Applied Approach
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The Quarterly Review of Biology, Volume 84, Issue 4, Page 420, December 2009. (Source: QRB Latest Issue)
Source: QRB Latest Issue - November 19, 2009 Category: Biology Tags: book review New Biological Books Source Type: journals
Index to Reviewers of Books Volume 84 (2009)
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The Quarterly Review of Biology, Volume 84, Issue 4, Page 447-449, December 2009. (Source: QRB Latest Issue)
Source: QRB Latest Issue - November 19, 2009 Category: Biology Tags: article Source Type: journals
Book Review: Directory of Publishers
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The Quarterly Review of Biology, Volume 84, Issue 4, Page 428-429, December 2009. (Source: QRB Latest Issue)
Source: QRB Latest Issue - November 19, 2009 Category: Biology Tags: book review New Biological Books Source Type: journals
Titles and Authors of Articles
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The Quarterly Review of Biology, Volume 84, Issue 4, Page 431-432, December 2009. (Source: QRB Latest Issue)
Source: QRB Latest Issue - November 19, 2009 Category: Biology Tags: article Source Type: journals
Book Review: What a Time I am Having: Selected Letters of Max Perutz
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The Quarterly Review of Biology, Volume 84, Issue 4, Page 399-400, December 2009. (Source: QRB Latest Issue)
Source: QRB Latest Issue - November 19, 2009 Category: Biology Tags: book review New Biological Books Source Type: journals
Book Review: Treasure Your Exceptions: The Science and Life of William Bateson
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The Quarterly Review of Biology, Volume 84, Issue 4, Page 398-399, December 2009. (Source: QRB Latest Issue)
Source: QRB Latest Issue - November 19, 2009 Category: Biology Tags: book review New Biological Books Source Type: journals
Book Review: Urban Herpetology
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The Quarterly Review of Biology, Volume 84, Issue 4, Page 423, December 2009. (Source: QRB Latest Issue)
Source: QRB Latest Issue - November 19, 2009 Category: Biology Tags: book review New Biological Books Source Type: journals
Book Review: A Sea without Fish: Life in the Ordovician Sea of the Cincinnati Region
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The Quarterly Review of Biology, Volume 84, Issue 4, Page 404, December 2009. (Source: QRB Latest Issue)
Source: QRB Latest Issue - November 19, 2009 Category: Biology Tags: book review New Biological Books Source Type: journals
Book Review: Marine Ornamental Shrimp: Biology, Aquaculture and Conservation
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The Quarterly Review of Biology, Volume 84, Issue 4, Page 423, December 2009. (Source: QRB Latest Issue)
Source: QRB Latest Issue - November 19, 2009 Category: Biology Tags: book review New Biological Books Source Type: journals
Book Review: Mixed Effects Models and Extensions in Ecology with R
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The Quarterly Review of Biology, Volume 84, Issue 4, Page 404-405, December 2009. (Source: QRB Latest Issue)
Source: QRB Latest Issue - November 19, 2009 Category: Biology Tags: book review New Biological Books Source Type: journals
