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This page shows you the most recent publications within this specialty of the MedWorm directory.

Mapping of Contributions From Collateral Ligaments to Overall Knee Joint Constraint: An Experimental Cadaveric Study
Understanding the contribution of the soft-tissues to total joint constraint (TJC) is important for predicting joint kinematics, developing surgical procedures, and increasing accuracy of computational models. Previous studies on the collateral ligaments have focused on quantifying strain and tension properties under discrete loads or kinematic paths; however, there has been little work to quantify collateral ligament contribution over a broad range of applied loads and range of motion (ROM) in passive constraint. To accomplish this, passive envelopes were collected from nine cadaveric knees instrumented with implantable p...
Source: Journal of Biomechanical Engineering - March 27, 2015 Category: Biomedical Engineering Source Type: research

Stability of Carotid Artery Under Steady-State and Pulsatile Blood Flow: A Fluid–Structure Interaction Study
The objective of this study was to simulate the buckling and post-buckling behaviors of the carotid artery under pulsatile flow using a fully coupled fluid–structure interaction (FSI) method. The artery wall was modeled as a nonlinear material with a two-fiber strain-energy function. FSI simulations were performed under steady-state flow and pulsatile flow conditions with a prescribed flow velocity profile at the inlet and different pressures at the outlet to determine the critical buckling pressure. Simulations were performed for normal (160 ml/min) and high (350 ml/min) flow rates and normal (1.5) and reduced (1.3) axi...
Source: Journal of Biomechanical Engineering - March 27, 2015 Category: Biomedical Engineering Source Type: research

A Three-Dimensional Ankle Kinetostatic Model to Simulate Loaded and Unloaded Joint Motion
A kinetostatic model able to replicate both the natural unloaded motion of the tibiotalar (or ankle) joint and the joint behavior under external loads is presented. The model is developed as the second step of a sequential procedure, which allows the definition of a kinetostatic model as a generalization of a kinematic model of the joint defined at the first step. Specifically, this kinematic model taken as the starting point of the definition procedure is a parallel spatial mechanism which replicates the ankle unloaded motion. It features two rigid bodies (representing the tibia–fibula and the talus–calcaneus complexe...
Source: Journal of Biomechanical Engineering - March 27, 2015 Category: Biomedical Engineering Source Type: research

A Class of Multivariate Denoising Algorithms Based on Synchrosqueezing
Univariate thresholding techniques based on high resolution time-frequency algorithms, such as the synchrosqueezing transform, have emerged as important tools in removing noise from real world data. Low cost multichannel sensor technology has highlighted the need for direct multivariate denoising, and to this end, we introduce a class of multivariate denoising techniques based on the synchrosqueezing transform. This is achieved by partitioning the time-frequency domain so as to identify a set of modulated oscillations common to the constituent data channels within multivariate data, and by employing a modified universal th...
Source: IEEE Transactions on Signal Processing - March 27, 2015 Category: Biomedical Engineering Source Type: research

Clutter Subspace Estimation in Low Rank Heterogeneous Noise Context
This paper addresses the problem of the Clutter Subspace Projector (CSP) estimation in the context of a disturbance composed of a Low Rank (LR) heterogeneous clutter, modeled here by a Spherically Invariant Random Vector (SIRV), plus a white Gaussian noise (WGN). In such context, the corresponding LR adaptive filters and detectors require less training vectors than classical methods to reach equivalent performance. Unlike classical adaptive processes, which are based on an estimate of the noise Covariance Matrix (CM), the LR processes are based on a CSP estimate. This CSP estimate is usually derived from a Singular Value D...
Source: IEEE Transactions on Signal Processing - March 27, 2015 Category: Biomedical Engineering Source Type: research

Low-Complexity Multiclass Encryption by Compressed Sensing
The idea that compressed sensing may be used to encrypt information from unauthorized receivers has already been envisioned but never explored in depth since its security may seem compromised by the linearity of its encoding process. In this paper, we apply this simple encoding to define a general private-key encryption scheme in which a transmitter distributes the same encoded measurements to receivers of different classes, which are provided partially corrupted encoding matrices and are thus allowed to decode the acquired signal at provably different levels of recovery quality. The security properties of this scheme are ...
Source: IEEE Transactions on Signal Processing - March 27, 2015 Category: Biomedical Engineering Source Type: research

Corrections to “A Neuro-Fuzzy Approach for Medical Image Fusion” [Dec 13 3347-3353]
The title of the paper in reference (S. Das and M. K. Kundu, ???A neuro-fuzzy approach for medical image fusion,??? IEEE Trans. Biomed. Eng., vol. 60, no. 12, pp. 3347???3353) should have read ???A note on grey level-intensity transformation: effect on HVS thresholding.??? (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - March 27, 2015 Category: Biomedical Engineering Source Type: research

East Africa: Rwanda to Champion E-Health in EAC
[New Times] Rwanda was yesterday selected to be East Africa's centre of excellence in e-health and biomedical engineering as well as health vaccines and immunisation logistics. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - March 26, 2015 Category: African Health Source Type: news

Hand-in-hand advances in biomedical engineering and sensorimotor restoration - Pisotta I, Perruchoud D, Ionta S.
BACKGROUND: Living in a multisensory world entails the continuous sensory processing of environmental information in order to enact appropriate motor routines. The interaction between our body and our brain is the crucial factor for achieving such sensorim... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - March 26, 2015 Category: Global & Universal Tags: Engineering, Physics, Structural Soundness and Failure Source Type: news

A soft, stretchable and conductive biointerface for cell mechanobiology.
Abstract In mechanobiology the study of cell response to mechanical stimuli is fundamental, and the involved processes (i.e., mechanotransduction) need to be investigated by interfacing (mechanically and electrically) with the cells in dynamic and non-invasive natural-like conditions. In this work, we present a novel soft, stretchable and conductive biointerface that allows both cell mechanical stimulation and dynamic impedance recording. The biointerface stretchability and conductivity, jointly to the biocompatibility and transparency needed to perform cell culture studies, were obtained by exploiting the formatio...
Source: Biomedical Microdevices - March 24, 2015 Category: Biomedical Engineering Authors: Bernardeschi I, Greco F, Ciofani G, Marino A, Mattoli V, Mazzolai B, Beccai L Tags: Biomed Microdevices Source Type: research

Rotational Stiffness of American Football Shoes Affects Ankle Biomechanics and Injury Severity
While previous studies have investigated the effect of shoe–surface interaction on injury risk, few studies have examined the effect of rotational stiffness of the shoe. The hypothesis of the current study was that ankles externally rotated to failure in shoes with low rotational stiffness would allow more talus eversion than those in shoes with a higher rotational stiffness, resulting in less severe injury. Twelve (six pairs) cadaver lower extremities were externally rotated to gross failure while positioned in 20 deg of pre-eversion and 20 deg of predorsiflexion by fixing the distal end of the foot, axially loading...
Source: Journal of Biomechanical Engineering - March 24, 2015 Category: Biomedical Engineering Source Type: research

In vitro-analysis of kinematics and intradiscal pressures in cervical arthroplasty versus fusion – A biomechanical study in a sheep model with two semi-constrained prosthesis
Conclusion: The results of this biomechanical study indicate that single-level implantation of semi-constrained TDR lead to a certain hypermobility in the treated segments with lowering the ROM in the adjacent levels in almost all situations. (Source: BioMedical Engineering OnLine)
Source: BioMedical Engineering OnLine - March 24, 2015 Category: Biomedical Engineering Authors: Dorothea DaentzerBastian WelkeChristof HurschlerNathalie HusmannChristina JansenChristian FlammeBerna Richter Source Type: research

Robust phase-based texture descriptor for classification of breast ultrasound images
Background: Classification of breast ultrasound (BUS) images is an important step in the computer-aided diagnosis (CAD) system for breast cancer. In this paper, a novel phase-based texture descriptor is proposed for efficient and robust classifiers to discriminate benign and malignant tumors in BUS images.MethodThe proposed descriptor, namely the phased congruency-based binary pattern (PCBP) is an oriented local texture descriptor that combines the phase congruency (PC) approach with the local binary pattern (LBP). The support vector machine (SVM) is further applied for the tumor classification. To verify the efficiency of...
Source: BioMedical Engineering OnLine - March 24, 2015 Category: Biomedical Engineering Authors: Lingyun CaiXin WangYuanyuan WangYi GuoJinhua YuYi Wang Source Type: research

Sensors, Vol. 15, Pages 6947-6995: The Application of Biomedical Engineering Techniques to the Diagnosis and Management of Tropical Diseases: A Review
This paper reviews a number of biomedical engineering approaches to help aid in the detection and treatment of tropical diseases such as dengue, malaria, cholera, schistosomiasis, lymphatic filariasis, ebola, leprosy, leishmaniasis, and American trypanosomiasis (Chagas). Many different forms of non-invasive approaches such as ultrasound, echocardiography and electrocardiography, bioelectrical impedance, optical detection, simplified and rapid serological tests such as lab-on-chip and micro-/nano-fluidic platforms and medical support systems such as artificial intelligence clinical support systems are discussed. The paper a...
Source: Sensors - March 23, 2015 Category: Biotechnology Authors: Fatimah IbrahimTzer ThioTarig FaisalMichael Neuman Tags: Review Source Type: research

Drug coated microneedles for minimally-invasive treatment of oral carcinomas: development and in vitro evaluation.
The objective of this study was to develop coated microneedles as a novel device for direct and minimally invasive intratumoral delivery of anti-cancer drugs. Poly(lactic-co-glycolic) acid (PLGA) nanoparticles encapsulating doxorubicin (DOX) were prepared and coated on inplane (1D) microneedles. Microscopic evaluation of 3D tissue phantoms and porcine cadaver buccal tissues that were treated with 1D microneedle arrays coated with DOX-PLGA nanoparticles demonstrated that DOX could diffuse both laterally and vertically in to the tissues and produced cellular cytotoxicity. Out of plane (2D) microneedle arrays measuring 1 cm ...
Source: Biomedical Microdevices - March 22, 2015 Category: Biomedical Engineering Authors: Ma Y, Boese SE, Luo Z, Nitin N, Gill HS Tags: Biomed Microdevices Source Type: research

Tapered-slit membrane filters for high-throughput viable circulating tumor cell isolation.
Abstract This paper presents tapered-slit membrane filters for high-throughput viable circulating tumor cell (CTC) isolation. The membrane filter with a 2D array of vertical tapered slits with a gap that is wide at the entrance and gradually decreases with depth, provide minimal cell stress and reduce 82.14 % of the stress generated in conventional straight-hole filters. We designed two types of tapered-slit filters, Filters 6 and 8, respectively, containing the tapered slits with outlet widths of 6 μm and 8 μm at a slit density of 34,445/cm(2) on the membrane. We fabricated the vertical slits with a tapered a...
Source: Biomedical Microdevices - March 22, 2015 Category: Biomedical Engineering Authors: Kang YT, Doh I, Cho YH Tags: Biomed Microdevices Source Type: research

Heart monitoring using left ventricle impedance and ventricular electrocardiography in left ventricular assist device patients
Background: Patients who develop critical arrhythmia during left ventricular assist device (LVAD) perfusion have a low survival rate. For diagnosis of unexpected heart abnormalities, new heart-monitoring methods are required for patients supported by LVAD perfusion. Ventricular electrocardiography using electrodes implanted in the ventricle to detect heart contractions is unsuitable if the heart is abnormal. Left ventricular impedance (LVI) is useful for monitoring heart movement but does not show abnormal action potential in the heart muscle.ObjectivesTo detect detailed abnormal heart conditions, we obtained ventricular e...
Source: BioMedical Engineering OnLine - March 21, 2015 Category: Biomedical Engineering Authors: Keun HerChi AhnSung ParkSeong Choi Source Type: research

Erratum to: Pulsatile Perfusion Bioreactor System for Durability Testing and Compliance Estimation of Tissue Engineered Vascular Grafts.
PMID: 25794963 [PubMed - as supplied by publisher] (Source: Annals of Biomedical Engineering)
Source: Annals of Biomedical Engineering - March 21, 2015 Category: Biomedical Engineering Authors: Diamantouros SE, Hurtado-Aguilar LG, Schmitz-Rode T, Mela P, Jockenhoevel S Tags: Ann Biomed Eng Source Type: research

A Systematic Assessment of the Use of Platelet-Rich Plasma in Spinal Fusion.
The objective of this review is to systematically discuss the role of PRP in augmentation of bone regeneration for the purpose of spinal fusion. Background information on PRP, including a discussion of its preparation, activation, and growth factors, is included. Additionally, data from in vitro studies utilizing PRP in bone tissue engineering strategies is analyzed, and the available animal and clinical studies are systematically reviewed in order to provide guidance on future research pathways as well as the potential role of PRP in spinal fusion surgery. PMID: 25794962 [PubMed - as supplied by publisher] (Source: An...
Source: Annals of Biomedical Engineering - March 21, 2015 Category: Biomedical Engineering Authors: Elder BD, Holmes C, Goodwin CR, Lo SF, Puvanesarajah V, Kosztowski TA, Locke JE, Witham TF Tags: Ann Biomed Eng Source Type: research

Five-Dimensional Depth-Velocity Filtering for Enhancing Moving Objects in Light Field Videos
Five-dimensional (5-D) light field video (LFV) (also known as plenoptic video) is a more powerful form of representing information of dynamic scenes compared to conventional three-dimensional (3-D) video. In this paper, the 5-D spectrum of an object in an LFV is derived for the important practical case of objects moving with constant velocity and at constant depth. In particular, it is shown that the region of support (ROS) of the 5-D spectrum is a skewed 3-D hyperfan in the 5-D frequency domain, with the degree of skew depending on the velocity and depth of the moving object. Based on this analysis, a 5-D depth-velocity d...
Source: IEEE Transactions on Signal Processing - March 20, 2015 Category: Biomedical Engineering Source Type: research

Generalized Selection Combining for Cognitive Relay Networks Over Nakagami- Fading
We consider transmit antenna selection with receive generalized selection combining (TAS/GSC) for cognitive decode-and-forward (DF) relaying in Nakagami-$m$ fading channels. In an effort to assess the performance, the probability density function and the cumulative distribution function of the end-to-end SNR are derived using the moment generating function, from which new exact closed-form expressions for the outage probability and the symbol error rate are derived. We then derive a new closed-form expression for the ergodic capacity. More important, by deriving the asymptotic expressions for the outage probability and the...
Source: IEEE Transactions on Signal Processing - March 20, 2015 Category: Biomedical Engineering Source Type: research

Table of Contents
Presents the table of contents for this issue of the publication. (Source: IEEE Transactions on Signal Processing)
Source: IEEE Transactions on Signal Processing - March 20, 2015 Category: Biomedical Engineering Source Type: research

IEEE Transactions on Biomedical Engineering information for authors
Presents information for authors publishing in this journal. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - March 20, 2015 Category: Biomedical Engineering Source Type: research

IEEE Transactions on Biomedical Engineering Handling Editors
Presents a listing of associate editors for this publication. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - March 20, 2015 Category: Biomedical Engineering Source Type: research

Call for Nominations 2014-2015 Region 9 Biennial Outstanding Student Paper Award
Presents information regarding the call for nominations for the 2014-2015 Region 9 Biennial Outstanding Student Paper Award. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - March 20, 2015 Category: Biomedical Engineering Source Type: research

Expiration-Phase Template-Based Motion Correction of Free-Breathing Abdominal Dynamic Contrast Enhanced MRI
This paper studies a novel method to compensate for respiratory and peristaltic motions in abdominal dynamic contrast enhanced magnetic resonance imaging. The method consists of two steps: 1) expiration-phase “template” construction and retrospective gating of the data to the template; and 2) nonrigid registration of the gated volumes. Landmarks annotated by three experts were used to directly assess the registration performance. A tri-exponential function fit to time intensity curves from regions of interest was used to indirectly assess the performance. One of the parameters of the tri-exponential fit was u...
Source: IEEE Transactions on Biomedical Engineering - March 20, 2015 Category: Biomedical Engineering Source Type: research

Corrections to “A Neuro-Fuzzy Approach for Medical Image Fusion”
The title of the paper in reference ( S. Das and M. K. Kundu, ???A neuro-fuzzy approach for medical image fusion,??? IEEE Trans. Biomed. Eng., vol. 60, no. 12, pp. 3347???3353) should have read ???A note on grey level-intensity transformation: effect on HVS thresholding.??? (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - March 20, 2015 Category: Biomedical Engineering Source Type: research

Announcing a new IEEE working group for Location Services for healthcare
Presents information on the new IEEE working group for Location Services for healthcare. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - March 20, 2015 Category: Biomedical Engineering Source Type: research

Topological Modeling and Classification of Mammographic Microcalcification Clusters
Conclusion: The results indicate that the proposed approach is able to outperform the current state-of-the-art methods. Significance: This study shows that topology modeling is an important tool for microcalcification analysis not only because of the improved classification accuracy but also because the topological measures can be linked to clinical understanding. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - March 20, 2015 Category: Biomedical Engineering Source Type: research

Wavelet-Based Regularization for Robust Microwave Imaging in Medical Applications
Microwave imaging (MWI) is an emerging tool for medical diagnostics, potentially offering unique advantages such as the capability of providing quantitative images of the inspected tissues. This involves, however, solving a challenging nonlinear and ill-posed electromagnetic inverse scattering problem. This paper presents a robust method for quantitative MWI in medical applications where very little, if any, a priori information on the imaging scenario is available. This is accomplished by employing a distorted Born iterative method and a regularization by projection technique, which reconstructs the tissue parameters usin...
Source: IEEE Transactions on Biomedical Engineering - March 20, 2015 Category: Biomedical Engineering Source Type: research

Wavelet Augmented Cough Analysis for Rapid Childhood Pneumonia Diagnosis
Pneumonia is the cause of death for over a million children each year around the world, largely in resource poor regions such as sub-Saharan Africa and remote Asia. One of the biggest challenges faced by pneumonia endemic countries is the absence of a field deployable diagnostic tool that is rapid, low-cost and accurate. In this paper, we address this issue and propose a method to screen pneumonia based on the mathematical analysis of cough sounds. In particular, we propose a novel cough feature inspired by wavelet-based crackle detection work in lung sound analysis. These features are then combined with other mathematical...
Source: IEEE Transactions on Biomedical Engineering - March 20, 2015 Category: Biomedical Engineering Source Type: research

Ultrasound Elasticity Imaging for Determining the Mechanical Properties of Human Posterior Tibial Tendon: A Cadaveric Study
This study suggests that UEI could be a reliable in vivo technique for estimating the mechanical properties of the PTT, and as a clinical tool, help guide treatment decisions for advanced PTTD and other tendinopathies. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - March 20, 2015 Category: Biomedical Engineering Source Type: research

Assess Sleep Stage by Modern Signal Processing Techniques
In this paper, two modern adaptive signal processing techniques, empirical intrinsic geometry and synchrosqueezing transform, are applied to quantify different dynamical features of the respiratory and electroencephalographic signals. We show that the proposed features are theoretically rigorously supported, as well as capture the sleep information hidden inside the signals. The features are used as input to multiclass support vector machines with the radial basis function to automatically classify sleep stages. The effectiveness of the classification based on the proposed features is shown to be comparable to human expert...
Source: IEEE Transactions on Biomedical Engineering - March 20, 2015 Category: Biomedical Engineering Source Type: research