Biomedical Engineering Biomedical Engineering RSS feedThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 13.

Tailoring the hybrid palliation for hypoplastic left heart syndrome: A simulation study using a lumped parameter model
The management of HLHS with the HP is challenging as it depends on several variables [1,9]. In fact, Q p/Q s depends on the PDA dimensions, PAB tightness, ASD dimension, systemic and pulmonary resistances regulation in the post operative management [[1,2,6],[9–11],[14],[18–20]]. Additionally, the coronary and cerebral circulations depend on retrograde perfusion assured by the PDA stent [19]. The placement of a RevBT was proposed to maintain the coronary and brain perfusion in patients with limited/absent anterograde flow from the left ventricle, high risk of CoAo development after the HP, hypoplastic aorta [[2,9,14...
Source: Medical Engineering and Physics - July 24, 2015 Category: Biomedical Engineering Authors: A. Di Molfetta, M. Pilati, M.G. Gagliardi, L. Fresiello, A. Amodeo, A. Cristofaletti, G. Pongiglione, G. Ferrari Tags: Technical note Source Type: research

Discipline : bloc operatoire
Publication date: Available online 23 July 2015 Source:IRBM News (Source: IRBM News)
Source: IRBM News - July 24, 2015 Category: Biomedical Engineering Source Type: research

Hidden pattern discovery on epileptic EEG with 1-D local binary patterns and epileptic seizures detection by grey relational analysis
In this study, 1D-LBP, which utilizes all data points, was employed for extracting features in raw EEG signals, Fisher score (FS) was employed to select the representative features, which can also be determined as hidden patterns. Additionally, GRA is performed to classify EEG signals through these Fisher scored features. The experimental results of the proposed approach, which was employed in a public dataset for validation, showed that it has a high accuracy in identifying epileptic EEG signals. For various combinations of epileptic EEG, such as A–E, B–E, C–E, D–E, and A–D clusters, 100, 96, 100, 99.00 and 100...
Source: Australasian Physical and Engineering Sciences in Medicine - July 24, 2015 Category: Biomedical Engineering Source Type: research

Age and sex-specific relationships between blood pressure variability and carotid intima-media thickness
This study evaluated the association between carotid intima-media thickness (IMT) and 24 h ambulatory blood pressure variability (BPV) in 150 subjects. The subjects were divided into different age groups and gender groups. We found that for the subjects aged less than 45 years, 24 h and daytime diastolic BPV were associated with the increased IMT (r = 0.525, P = 0.018; r = 0.507, P = 0.022). For the middle aged people (46–55 years), daytime (r = 0.377, P = 0.014) and 24 h systolic BPV (r = 0.366, P = 0.017) were more related to the increases in IMT than 24 h diastolic BPV (r = 0.320, P = 0.039)....
Source: Australasian Physical and Engineering Sciences in Medicine - July 24, 2015 Category: Biomedical Engineering Source Type: research

Treatment of the distal fracture in radioulna based on the volar wrist dual channel approach and postoperative X-ray diagnosis
In this study, we implemented the improved palmar wrist surgery by a volar wrist dual channel approach. Between 2011 and 2014, we have treated 67 distal radius fracture patients. We divided them into two parts randomly, and treat them by the Carpometacarpal direct approach solution and dual wrist palmar surgical approach solution respectively. After the surgery, the differences in the incidence of median nerve irritation are significant (P < 0.01). With reference to the exposure time of fracture, the operation time and the pronator quadratus muscle repair rate, we find that the exposure time of fracture and the operat...
Source: Australasian Physical and Engineering Sciences in Medicine - July 24, 2015 Category: Biomedical Engineering Source Type: research

Novel immobilization process of a thermophilic catalase: efficient purification by heat treatment and subsequent immobilization at high temperature.
Abstract The main goal of the present work is to investigate a novel process of purification and immobilization of a thermophilic catalase at high temperatures. The catalase, originated from Bacillus sp., was overexpressed in a recombinant Escherichia coli BL21(DE3)/pET28-CATHis and efficiently purified by heat treatment, achieving a threefold purification. The purified catalase was then immobilized onto an epoxy support at different temperatures (25, 40, and 55 °C). The immobilizate obtained at higher temperatures reached its maximum activity in a shorter time than that obtained at lower temperatures. Furthermor...
Source: Bioprocess and Biosystems Engineering - July 24, 2015 Category: Biomedical Engineering Authors: Xu J, Luo H, López C, Xiao J, Chang Y Tags: Bioprocess Biosyst Eng Source Type: research

Unstructured hexahedral mesh generation of complex vascular trees using a multi-block grid-based approach.
Abstract The trend towards realistic numerical models of (pathologic) patient-specific vascular structures brings along larger computational domains and more complex geometries, increasing both the computation time and the operator time. Hexahedral grids effectively lower the computational run time and the required computational infrastructure, but at high cost in terms of operator time and minimal cell quality, especially when the computational analyses are targeting complex geometries such as aneurysm necks, severe stenoses and bifurcations. Moreover, such grids generally do not allow local refinements. As an att...
Source: Computer Methods in Biomechanics and Biomedical Engineering - July 24, 2015 Category: Biomedical Engineering Authors: Bols J, Taelman L, De Santis G, Degroote J, Verhegghe B, Segers P, Vierendeels J Tags: Comput Methods Biomech Biomed Engin Source Type: research

Comparison of three formal methods used to estimate the functional axis of rotation: an extensive in-vivo analysis performed on the knee joint.
This study compared three formal methods used to estimate functional AoR, namely a cylindrical fitting method, a mean helical axis transformation, and a symmetrical axis approach. These methods were tested on 106 subjects undergoing navigated total knee arthroplasty. AoR orientation in 3D and in the frontal and coronal planes provided by each method was compared to the transepicondylar axis direction. Although all the methods resulted effective, significant differences were identified among them, relatively to the orientation in 3D and in the frontal plane projection. This was probably due to the presence of secondary rota...
Source: Computer Methods in Biomechanics and Biomedical Engineering - July 24, 2015 Category: Biomedical Engineering Authors: Colle F, Lopomo N, Visani A, Zaffagnini S, Marcacci M Tags: Comput Methods Biomech Biomed Engin Source Type: research

Mathematical models of α-synuclein transport in axons.
Abstract To investigate possible effects of diffusion on α-synuclein (α-syn) transport in axons, we developed two models of α-syn transport, one that assumes that α-syn is transported only by active transport, as part of multiprotein complexes, and a second that assumes an interplay between motor-driven and diffusion-driven α-syn transport. By comparing predictions of the two models, we were able to investigate how diffusion could influence axonal transport of α-syn. The predictions obtained could be useful for future experimental work aimed at elucidating the mechanisms of axonal transport of α-syn. We also...
Source: Computer Methods in Biomechanics and Biomedical Engineering - July 24, 2015 Category: Biomedical Engineering Authors: Kuznetsov IA, Kuznetsov AV Tags: Comput Methods Biomech Biomed Engin Source Type: research

The Role of Synthetic Extracellular Matrices in Endothelial Progenitor Cell Homing for Treatment of Vascular Disease.
Abstract Poor vascular homeostasis drives many clinical disorders including diabetes, arthritis, atherosclerosis, and peripheral artery disease. Local tissue ischemia resultant of insufficient blood flow is a potent stimulus for recruitment of endothelial progenitor cells (EPCs). This mobilization and homing is a multi-step process involving EPC detachment from their steady state bone marrow niches, entry into circulation, rolling along vessel endothelium, transmigration, and adhesion to denuded extracellular matrix (ECM) where they may participate in neovessel formation. However, these events are often interrupted...
Source: Annals of Biomedical Engineering - July 24, 2015 Category: Biomedical Engineering Authors: Williams PA, Silva EA Tags: Ann Biomed Eng Source Type: research

Predicting Knee Osteoarthritis.
Abstract Treatment options for osteoarthritis (OA) beyond pain relief or total knee replacement are very limited. Because of this, attention has shifted to identifying which factors increase the risk of OA in vulnerable populations in order to be able to give recommendations to delay disease onset or to slow disease progression. The gold standard is then to use principles of risk management, first to provide subject-specific estimates of risk and then to find ways of reducing that risk. Population studies of OA risk based on statistical associations do not provide such individually tailored information. Here we arg...
Source: Annals of Biomedical Engineering - July 24, 2015 Category: Biomedical Engineering Authors: Gardiner BS, Woodhouse FG, Besier TF, Grodzinsky AJ, Lloyd DG, Zhang L, Smith DW Tags: Ann Biomed Eng Source Type: research

Robot-aided in vitro measurement of patellar stability with consideration to the influence of muscle loading
Background: Anterior knee pain is often associated with patellar maltracking and instability. However, objective measurement of patellar stability under clinical and experimental conditions is difficult, and muscular activity influences the results. In the present study, a new experimental setting for in vitro measurement of patellar stability was developed and the mediolateral force–displacement behavior of the native knee analyzed with special emphasis on patellar tilt and muscle loading. Methods: In the new experimental setup, two established testing methods were combined: an upright knee simulator for positioning and...
Source: BioMedical Engineering OnLine - July 23, 2015 Category: Biomedical Engineering Authors: Andrea LorenzEvgenij BobrowitschMarkus WünschelChristian WalterNikolaus WülkerUlf Leichtle Source Type: research

Detection of central fixation using short-time autoregressive spectral estimation during retinal birefringence scanning
The human fovea is the most sensitive part of the retina, projecting the objects in the direction of gaze. The polarization-changing property (birefringence) of the Henle fibers surrounding the fovea has been used to identify its position and hence the direction of gaze [1–5]. This allows checking for eye alignment and strabismus – a major risk factor for amblyopia. Screening techniques and an instrument have been reported by Hunter et al., based on the birefringence signal derived from circular scanning in the foveal region [6]. (Source: Medical Engineering and Physics)
Source: Medical Engineering and Physics - July 23, 2015 Category: Biomedical Engineering Authors: Boris I. Gramatikov Source Type: research

46th Mary McMillan Lecture: Not Eureka.
Abstract Lynn Snyder-Mackler, PT, PhD, ScD, SCS, ATC, FAPTA, for more than 25 years, has been a leader in developing evidence-based approaches for the rehabilitation of knee injuries, educating new physical therapy professionals and mentoring future rehabilitation scientists. She has received almost all of APTA's distinguished awards and is an international leader in physical therapy.Holding several positions and appointments at the University of Delaware, Dr Snyder-Mackler is Alumni Distinguished Professor of Physical Therapy, Academic Director of the Delaware Physical Therapy Clinic, Faculty Athletics Representat...
Source: Physical Therapy - July 23, 2015 Category: Physiotherapy Authors: Snyder-Mackler L Tags: Phys Ther Source Type: research

Dielectrophoresis-Mediated Electrodeformation as a Means of Determining Individual Platelet Stiffness.
Abstract Platelets, essential for hemostasis, are easily activated via biochemical and mechanical stimuli. Cell stiffness is a vital parameter modulating the mechano-transduction of exogenous mechanical stimuli. While methods exist to measure cell stiffness, no ready method exists for measuring platelet stiffness that is both minimally-contacting, imparting minimal exogenous force and non-activating. We developed a minimal-contact methodology capable of trapping and measuring the stiffness of individual platelets utilizing dielectrophoresis (DEP)-mediated electrodeformation. Parametric studies demonstrate a non-uni...
Source: Annals of Biomedical Engineering - July 23, 2015 Category: Biomedical Engineering Authors: Leung SL, Lu Y, Bluestein D, Slepian MJ Tags: Ann Biomed Eng Source Type: research

An integrated CAD/CAM/robotic milling method for custom cementless femoral prostheses
A custom cementless femoral prosthesis can improve the fit and fill of a prosthesis in the femoral cavity and increase the primary stability of the prosthesis [1–3]. The primary cause of cementless femoral prosthesis failure is aseptic loosening. Aseptic loosening prevents the osseointegration of the proximal prosthesis, and long-term stability cannot be achieved [4,5]. The proper fit and fill of the prosthesis in the femoral cavity can increase the primary stability and improve the osseointegration of the proximal prosthesis. (Source: Medical Engineering and Physics)
Source: Medical Engineering and Physics - July 22, 2015 Category: Biomedical Engineering Authors: Xi Wen-ming, Wang Ai-min, Wu Qi, Liu Chang-Hua, Zhu Jian-fei, Xia Fang-fang Tags: Communication Source Type: research

Laboratory Evaluation of the gForce Tracker™, a Head Impact Kinematic Measuring Device for Use in Football Helmets.
This study sought to compare a new head impact-monitoring device, which is not limited to specific helmet styles, against reference accelerometer measurements. Laboratory controlled impacts were delivered using a linear pneumatic impactor to a Hybrid III headform (HIII) fitted with a football helmet and the impact monitoring device (gForce Tracker-GFT) affixed to the inside of the helmet. Linear regression analyses and absolute mean percent error (MAPE) were used to compare the head impact kinematics measured by the GFT to a reference accelerometer located at the HIII's center of mass. The coefficients of determination wer...
Source: Annals of Biomedical Engineering - July 22, 2015 Category: Biomedical Engineering Authors: Campbell KR, Warnica MJ, Levine IC, Brooks JS, Laing AC, Burkhart TA, Dickey JP Tags: Ann Biomed Eng Source Type: research

Editorial Board
(Source: Medical Engineering and Physics)
Source: Medical Engineering and Physics - July 21, 2015 Category: Biomedical Engineering Source Type: research

Call for Papers: The mechanobiology and biomechanics of chronic wounds: aetiology, prevention and treatment
(Source: Medical Engineering and Physics)
Source: Medical Engineering and Physics - July 21, 2015 Category: Biomedical Engineering Source Type: research

Comparison of the bending performance of solid and cannulated spinal pedicle screws using finite element analyses and biomechanical tests
Posterior pedicle screw and rod fixation systems have been widely used for the treatment of degenerative diseases of human spines and the stabilization of fractured vertebrae [1–3]. In clinical applications, spinal pedicle screws are the key components of pedicle screw and rod systems [4]. However, patients might have non-union or other complications when breakage, loosening, or pulling out of spinal pedicle screws occurs [5–7]. A breakage of spinal pedicle screws should be avoided because a broken screw fragment trapped in the vertebral body is difficult to remove and may impede subsequent revision surgeries [8]. (Sou...
Source: Medical Engineering and Physics - July 21, 2015 Category: Biomedical Engineering Authors: Kao-Shang Shih, Ching-Chi Hsu, Sheng-Mou Hou, Shan-Chuen Yu, Chen-Kun Liaw Source Type: research

NF S99-170 et ISO 9001 : la certification biomédicale accessible à tous !
Publication date: Available online 21 July 2015 Source:IRBM News Author(s): S. Collet, A. Vial, J. Taglia, Y. Yang, G. Farges (Source: IRBM News)
Source: IRBM News - July 21, 2015 Category: Biomedical Engineering Source Type: research

40e congrès Arab Health, Dubaï, 26–29 janvier 2015
Publication date: Available online 21 July 2015 Source:IRBM News Author(s): S. Favre Alther, H. Jacquemoud, F. M’madi (Source: IRBM News)
Source: IRBM News - July 21, 2015 Category: Biomedical Engineering Source Type: research

A new approach to blood flow simulation in vascular networks.
In conclusion, the present model provides a morphological foundation for future analysis of blood flow in the pulmonary circulation. PMID: 26195135 [PubMed - as supplied by publisher] (Source: Computer Methods in Biomechanics and Biomedical Engineering)
Source: Computer Methods in Biomechanics and Biomedical Engineering - July 21, 2015 Category: Biomedical Engineering Authors: Tamaddon H, Behnia M, Behnia M, Kritharides L Tags: Comput Methods Biomech Biomed Engin Source Type: research

A porohyperelastic finite element model of the eye: the influence of stiffness and permeability on intraocular pressure and optic nerve head biomechanics.
This study demonstrates that porohyperelastic modeling provides a novel method for computationally studying the biomechanical environment of the ONH. Porohyperelastic simulations of ocular tissues may help provide further insight into the complex biomechanical environment of posterior ocular tissues in POAG. PMID: 26195024 [PubMed - as supplied by publisher] (Source: Computer Methods in Biomechanics and Biomedical Engineering)
Source: Computer Methods in Biomechanics and Biomedical Engineering - July 21, 2015 Category: Biomedical Engineering Authors: Ayyalasomayajula A, Park RI, Simon BR, Vande Geest JP Tags: Comput Methods Biomech Biomed Engin Source Type: research

Computational method for the real-time calculation of the full-body muscle load distribution.
Abstract A method is described for minimising a quadratic function subject to equality and inequality constraints. This approach is applicable to solving the full-body muscle load distribution problem and calculating joint contact loads. It has been found that this approach can provide the solution on modest computing facilities and in significantly less time than using active set and interior point quadratic programming techniques. Hence the approach is suitable for providing real-time feedback to subjects undergoing biomechanical analysis of muscle, skeletal and joint loadings. PMID: 26194902 [PubMed - as sup...
Source: Computer Methods in Biomechanics and Biomedical Engineering - July 21, 2015 Category: Biomedical Engineering Authors: Shippen J Tags: Comput Methods Biomech Biomed Engin Source Type: research

Assessing the impact of including leaflets in the simulation of TAVI deployment into a patient-specific aortic root.
Abstract Computational simulation of transcatheter aortic valve implantation (TAVI) device deployment presents a significant challenge over and above similar simulations for percutaneous coronary intervention due to the presence of prosthetic leaflets. In light of the complexity of these leaflets, simulations have been performed to assess the effect of including the leaflets in a complete model of a balloon-expandable TAVI device when deployed in a patient-specific aortic root. Using an average model discrepancy metric, the average frame positions (with and without the leaflets) are shown to vary by 0.236% of the e...
Source: Computer Methods in Biomechanics and Biomedical Engineering - July 21, 2015 Category: Biomedical Engineering Authors: Bailey J, Curzen N, Bressloff NW Tags: Comput Methods Biomech Biomed Engin Source Type: research

Full-Length Recombinant Human Proteoglycan 4 Interacts with Hyaluronan to Provide Cartilage Boundary Lubrication.
This study demonstrates that rhPRG4 can adsorb to an intact articular cartilage surface and functions as an effective boundary lubricant, both alone and with HA, and provides the foundation for in vivo evaluation of this clinically relevant full-length rhPRG4 for treatment of osteoarthritis. PMID: 26194040 [PubMed - as supplied by publisher] (Source: Annals of Biomedical Engineering)
Source: Annals of Biomedical Engineering - July 21, 2015 Category: Biomedical Engineering Authors: Abubacker S, Dorosz SG, Ponjevic D, Jay GD, Matyas JR, Schmidt TA Tags: Ann Biomed Eng Source Type: research

Bone Pose Estimation in the Presence of Soft Tissue Artifact Using Triangular Cosserat Point Elements.
Abstract Accurate estimation of the position and orientation (pose) of a bone from a cluster of skin markers is limited mostly by the relative motion between the bone and the markers, which is known as the soft tissue artifact (STA). This work presents a method, based on continuum mechanics, to describe the kinematics of a cluster affected by STA. The cluster is characterized by triangular cosserat point elements (TCPEs) defined by all combinations of three markers. The effects of the STA on the TCPEs are quantified using three parameters describing the strain in each TCPE and the relative rotation and translation ...
Source: Annals of Biomedical Engineering - July 21, 2015 Category: Biomedical Engineering Authors: Solav D, Rubin MB, Cereatti A, Camomilla V, Wolf A Tags: Ann Biomed Eng Source Type: research

Here's how OHSU is breaking new ground in finding a cure for Alzheimer's
Dr. Jeffrey Kaye is one of a dozen Oregon Health & Science University researchers heading to Washington, D.C., to attend the Alzheimer’s Association International Conference. Kaye, a professor of neurology and biomedical engineering, shared some news on the latest developments in finding a cure for Alzheimer’s, the sixth-leading cause of death in the U.S. Kaye has some major chops when it comes to research on Alzheimer's. He is director of the OHSU Layton Aging & Alzheimer’s Disease Center,… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - July 20, 2015 Category: Biotechnology Authors: Rivkela Brodsky Source Type: news

Here's how OHSU is breaking new ground in finding a cure for Alzheimer's
Dr. Jeffrey Kaye is one of a dozen Oregon Health & Science University researchers heading to Washington, D.C., to attend the Alzheimer’s Association International Conference. Kaye, a professor of neurology and biomedical engineering, shared some news on the latest developments in finding a cure for Alzheimer’s, the sixth-leading cause of death in the U.S. Kaye has some major chops when it comes to research on Alzheimer's. He is director of the OHSU Layton Aging & Alzheimer’s Disease Center,… (Source: bizjournals.com Health Care:Hospitals headlines)
Source: bizjournals.com Health Care:Hospitals headlines - July 20, 2015 Category: Hospital Management Authors: Rivkela Brodsky Source Type: news

Table of Contents
Presents the table of contents for this issue of the publication. (Source: IEEE Transactions on Signal Processing)
Source: IEEE Transactions on Signal Processing - July 18, 2015 Category: Biomedical Engineering Source Type: research

IEEE Transactions on Biomedical Engineering Handling Editors
Provides a listing of board members, committee members and society officers. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - July 18, 2015 Category: Biomedical Engineering Source Type: research

Quantitative Analysis of Deformable Model-Based 3-D Reconstruction of Coronary Artery From Multiple Angiograms
Three-dimensional (3-D) reconstruction of the coronary artery is important for the diagnosis and interventional treatment of cardiovascular diseases. In this paper, a novel mean composited external force back-projective composition model is proposed and integrated into the deformable model framework for the 3-D reconstruction of coronary arteries from multiple angiograms. The parametric snake evolves toward the real vascular centerline in 3-D space based on the integrated internal energy and composited external energy. In addition, a polynomial function is constructed to determine the diameter of the cross section of the v...
Source: IEEE Transactions on Biomedical Engineering - July 18, 2015 Category: Biomedical Engineering Source Type: research