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Biomedical Engineering

This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 13.

Effect of an exclusion range of jaw movement data from the intercuspal positionon the estimation of the kinematic axis point
In patients who have lost natural occlusal contacts, the centric relation is usually estimated based on several anatomical factors such as the temporomandibular joint and masticatory muscles except dental arch. The clinical procedure to record the centric relation often depends on the clinician's expertise and technique; an objective method to determine proper occlusal position is desirable. The kinematic axis point (KAP) is kinematically estimated from sagittal movements and is an ideal posterior reference point that is used in dental articulators for reproducing jaw movement. (Source: Medical Engineering and Physics)
Source: Medical Engineering and Physics - July 19, 2014 Category: Biomedical Engineering Authors: Shuji Shigemoto, Nobuyuki Bando, Keisuke Nishigawa, Yoshitaka Suzuki, Toyoko Tajima, Kazuo Okura, Yoshizo Matsuka Source Type: research

Low torque levels can initiate a removal of the passivation layer and cause fretting in modular hip stems
Taper connections of modular hip prostheses are at risk of fretting and corrosion, which can result in reduced implant survival. The purpose of this study was to identify the minimum torque required to initiate a removal of the passivation layer at the taper interface as a function of assembly force and axial load.Titanium stems and cobalt–chromium heads were assembled with peak impaction forces of 4.5kN or 6.0kN and then mounted on a materials testing machine whilst immersed in Ringer's solution. (Source: Medical Engineering and Physics)
Source: Medical Engineering and Physics - July 19, 2014 Category: Biomedical Engineering Authors: S.Y. Jauch, L.G. Coles, L.V. Ng, A.W. Miles, H.S. Gill Source Type: research

Towards the Asymptotic Sum Capacity of the MIMO Cellular Two-Way Relay Channel
In this paper, we consider the transceiver and relay design for the multiple-input multiple-output (MIMO) cellular two-way relay channel (cTWRC), where a multi-antenna base station (BS) exchanges information with multiple multiantenna mobile stations via a multi-antenna relay station (RS). We propose a novel two-way relaying scheme to approach the sum capacity of the MIMO cTWRC. A key contribution of this work is a new nonlinear lattice-based precoding technique to precompensate the interstream interference, so as to achieve efficient interference-free lattice decoding at the relay. We derive sufficient conditions for the ...
Source: IEEE Transactions on Signal Processing - July 18, 2014 Category: Biomedical Engineering Source Type: research

Distributed Hybrid Power State Estimation Under PMU Sampling Phase Errors
Phasor measurement units (PMUs) have the advantage of providing direct measurements of power states. However, as the number of PMUs in a power system is limited, the traditional supervisory control and data acquisition (SCADA) system cannot be replaced by the PMU-based system overnight. Therefore, hybrid power state estimation taking advantage of both systems is important. As experiments show that sampling phase errors among PMUs are inevitable in practical deployment, this paper proposes a distributed power state estimation algorithm under PMU phase errors. The proposed distributed algorithm only involves local computatio...
Source: IEEE Transactions on Signal Processing - July 18, 2014 Category: Biomedical Engineering Source Type: research

IEEE Transactions on Biomedical Engineering information for authors
Provides instructions and guidelines to prospective authors who wish to submit manuscripts. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - July 18, 2014 Category: Biomedical Engineering Source Type: research

IEEE Transactions on Industrial Electronics publication information
(Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - July 18, 2014 Category: Biomedical Engineering Source Type: research

Preoperative Discrimination of Benign from Malignant Disease in Thyroid Nodules With Indeterminate Cytology Using Elastic Light-Scattering Spectroscopy
We describe the results of a large, prospective, blinded study validating the ESS algorithm in patients with thyroid nodules. An ESS system was used to acquire spectra from human thyroid tissue. Spectroscopic results were compared to the histopathology of the biopsy samples. Sensitivity and specificity of the ESS system in the differentiation of benign from malignant thyroid nodules are 74% and 90% respectively, with a negative predictive value of 97%. These data suggest that ESS has the potential for use in real time diagnosis of thyroid nodules as an adjunct to FNAB cytology. (Source: IEEE Transactio...
Source: IEEE Transactions on Biomedical Engineering - July 18, 2014 Category: Biomedical Engineering Source Type: research

Microwave Stethoscope: Development and Benchmarking of a Vital Signs Sensor Using Computer-Controlled Phantoms and Human Studies
This paper describes a new microwave-based method and associated measurement system for monitoring multiple vital signs (VS) as well as the changes in lung water content. The measurement procedure utilizes a single microwave sensor for reflection coefficient measurements, hence the name “microwave stethoscope (MiSt),” as opposed to the two-sensor transmission method previously proposed by the authors. To compensate for the reduced sensitivity due to reflection coefficient measurements, an improved microwave sensor design with enhanced matching to the skin and broadband operation, as well as an advanced digita...
Source: IEEE Transactions on Biomedical Engineering - July 18, 2014 Category: Biomedical Engineering Source Type: research

Wavelet-Based Localization of Oscillatory Sources From Magnetoencephalography Data
This study is aimed at describing, evaluating, and illustrating with clinical data a new method for localizing the sources of oscillatory cortical activity recorded by MEG. The method combines time–frequency representation and an entropic regularization technique in a common framework, assuming that brain activity is sparse in time and space. Spatial sparsity relies on the assumption that brain activity is organized among cortical parcels. Sparsity in time is achieved by transposing the inverse problem in the wavelet representation, for both data and sources. We propose an estimator of the wavelet coefficients of th...
Source: IEEE Transactions on Biomedical Engineering - July 18, 2014 Category: Biomedical Engineering Source Type: research

Tumor Localization Using Magnetic Nanoparticle-Induced Acoustic Signals
Cancer is a major public health problem worldwide, especially in developed countries. Early detection of cancer can greatly increase both survival rates and quality of life for patients. A magnetoacoustic-based method had been previously proposed for early tumor detection, in a minimal invasive procedure, using magnetic nanoparticles (MNPs). This paper presents a supporting localization algorithm that can provide the clinician with essential tumor location data and could enable a sequential biopsy. It provides localization algorithm development, as well as its validation in both computerized simulations and in vitro experi...
Source: IEEE Transactions on Biomedical Engineering - July 18, 2014 Category: Biomedical Engineering Source Type: research

Analysis of Low-Dimensional Radio-Frequency Impedance-Based Cardio-Synchronous Waveforms for Biometric Authentication
Over the past two decades, there have been a lot of advances in the field of pattern analyses for biomedical signals, which have helped in both medical diagnoses and in furthering our understanding of the human body. A relatively recent area of interest is the utility of biomedical signals in the field of biometrics, i.e., for user identification. Seminal work in this domain has already been done using electrocardiograph (ECG) signals. In this paper, we discuss our ongoing work in using a relatively recent modality of biomedical signals—a cardio-synchronous waveform measured using a Radio-Frequency Impedance-Interro...
Source: IEEE Transactions on Biomedical Engineering - July 18, 2014 Category: Biomedical Engineering Source Type: research

Caenorhabditis Elegans Segmentation Using Texture-Based Models for Motility Phenotyping
With widening interests in using model organisms for reverse genetic approaches and biomimmetic microrobotics, motility phenotyping of the nematode Caenorhabditis elegans is expanding across a growing array of locomotive environments. One ongoing bottleneck lies in providing users with automatic nematode segmentations of C. elegans in image sequences featuring complex and dynamic visual cues, a first and necessary step prior to extracting motility phenotypes. Here, we propose to tackle such automatic segmentation challenges by introducing a novel texture factor model (TFM). Our approach revolves around the use of combined ...
Source: IEEE Transactions on Biomedical Engineering - July 18, 2014 Category: Biomedical Engineering Source Type: research

Spatiotemporal Representations of Rapid Visual Target Detection: A Single-Trial EEG Classification Algorithm
Brain computer interface applications, developed for both healthy and clinical populations, critically depend on decoding brain activity in single trials. The goal of the present study was to detect distinctive spatiotemporal brain patterns within a set of event related responses. We introduce a novel classification algorithm, the spatially weighted FLD-PCA (SWFP), which is based on a two-step linear classification of event-related responses, using fisher linear discriminant (FLD) classifier and principal component analysis (PCA) for dimensionality reduction. As a benchmark algorithm, we consider the hierarchical discrimin...
Source: IEEE Transactions on Biomedical Engineering - July 18, 2014 Category: Biomedical Engineering Source Type: research

Combining Motor Imagery With Selective Sensation Toward a Hybrid-Modality BCI
A hybrid modality brain-computer interface (BCI) is proposed in this paper, which combines motor imagery with selective sensation to enhance the discrimination between left and right mental tasks, e.g., the classification between left/ right stimulation sensation and right/ left motor imagery. In this paradigm, wearable vibrotactile rings are used to stimulate both the skin on both wrists. Subjects are required to perform the mental tasks according to the randomly presented cues (i.e., left hand motor imagery, right hand motor imagery, left stimulation sensation or right stimulation sensation). Two-way ANOVA statistical an...
Source: IEEE Transactions on Biomedical Engineering - July 18, 2014 Category: Biomedical Engineering Source Type: research

Reduction of Edge Effect on Disk Electrodes by Optimized Current Waveform
Rectangular pulses applied to disk electrodes result in high current density at the edges of the disk, which can lead to electrode corrosion and tissue damage. We explored a method for reducing current density and corrosion, by varying the leading edge of the current pulse. Finite-element modeling and mathematical analysis were used to predict an optimal waveform that reduces current density at the edge while also maintaining short pulse duration. An approximation of the optimized waveform was implemented experimentally and applied to platinum disk electrodes. Surface analysis using energy-dispersive spectroscopy showed si...
Source: IEEE Transactions on Biomedical Engineering - July 18, 2014 Category: Biomedical Engineering Source Type: research

Tissue Doppler Imaging Optical Flow (TDIOF): A Combined B-Mode and Tissue Doppler Approach for Cardiac Motion Estimation in Echocardiographic Images
The quantitative analysis of cardiac motion from echocardiographic images helps clinicians in the diagnosis and therapy of patients suffering from heart disease. Quantitative analysis is usually based on tissue Doppler imaging (TDI) or speckle tracking. These methods are based on two techniques which to a large degree are independent: the Doppler phenomenon and image sequence processing. Herein, to increase the accuracy of the speckle tracking technique and to cope with the angle dependence of TDI, a combined approach dubbed tissue Doppler imaging optical flow (TDIOF) is proposed. TDIOF is formulated based on the combinati...
Source: IEEE Transactions on Biomedical Engineering - July 18, 2014 Category: Biomedical Engineering Source Type: research

Position-Dependent Characterization of Passive Wrist Stiffness
This study provides a characterization of passive wrist stiffness better suited to investigations of natural wrist rotations, which cover much of the wrist's ROM. It also provides a baseline for the study of neurological and/or orthopedic disorders that result in abnormal wrist stiffness. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - July 18, 2014 Category: Biomedical Engineering Source Type: research

An Optimal Decisional Space for the Classification of Alzheimer's Disease and Mild Cognitive Impairment
This paper proposes to combine MRI data with a neuropsychological test, mini-mental state examination (MMSE), as input to a multi-dimensional space for the classification of Alzheimer's disease (AD) and it's prodromal stages—mild cognitive impairment (MCI) including amnestic MCI (aMCI) and nonamnestic MCI (naMCI). The decisional space is constructed using those features deemed statistically significant through an elaborate feature selection and ranking mechanism. FreeSurfer was used to calculate 55 volumetric variables, which were then adjusted for intracranial volume, age and education. The classifica...
Source: IEEE Transactions on Biomedical Engineering - July 18, 2014 Category: Biomedical Engineering Source Type: research

IEEE Transactions on Biomedical Engineering publication information
(Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - July 18, 2014 Category: Biomedical Engineering Source Type: research

Table of Contents
(Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - July 18, 2014 Category: Biomedical Engineering Source Type: research

High-Order Statistics of Microtexton for HEp-2 Staining Pattern Classification
This study addresses the classification problem of the HEp-2 cell using indirect immunofluorescent (IIF) image analysis, which can indicate the presence of autoimmune diseases by finding antibodies in the patient serum. Generally, the method used for IIF analysis remains subjective, and depends too heavily on the experience and expertise of the physician. Recently, studies have shown that it is possible to identify the cell patterns using IIF image analysis and machine learning techniques. However, it still has large gap in recognition rates to the physical experts’ one. This paper explores an approach in which the ...
Source: IEEE Transactions on Biomedical Engineering - July 18, 2014 Category: Biomedical Engineering Source Type: research

Front Cover
(Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - July 18, 2014 Category: Biomedical Engineering Source Type: research

Design study of a Miniaturized Displacement Transducer (MDT) for an active middle ear implant system.
Abstract People suffering from moderate to severe hearing loss can be treated with active middle ear implants. A new approach in this field is to implant an electromechanical transducer onto the round window membrane in order to improve coupling and be able to treat patients with middle-ear problems. In this paper the design study for a miniaturized displacement transducer (MDT) for the round window is presented. Based on a requirement analysis, the basic principle and analytical modeling of the actuator is shown. A parameter variation study results in an optimized actuator configuration that is able to generate an...
Source: Biomedical Microdevices - July 18, 2014 Category: Biomedical Engineering Authors: Kaltenbacher D, Schächtele J, Goll E, Burkhardt C, Arnold H, Dalhoff E, Zenner HP Tags: Biomed Microdevices Source Type: research

Catalytic performance of functionalized polyurethane foam on the reductive decolorization of Reactive Red K-2G in up-flow anaerobic reactor under saline conditions.
Abstract Soluble anthraquinone compounds including anthraquinone-2-sulfonate (AQS) and anthraquinone-2,6-disulfonate can accelerate anaerobic decolorization of azo dyes. To realize the application of these compounds, the catalytic performance and stability of AQS-modified polyurethane foam (AQS-PUF) for Reactive Red K-2G decolorization were investigated in an up-flow anaerobic bioreactor under saline conditions. The results showed that the optimal influent pH value and hydraulic retention time were 7 and 10 h, respectively, in a continuous-flow bioreactor amended with AQS-PUF (R1). Under the above conditions, R1 (...
Source: Bioprocess and Biosystems Engineering - July 18, 2014 Category: Biomedical Engineering Authors: Zhou Y, Lu H, Wang J, Li J, Zhou J, Jin R Tags: Bioprocess Biosyst Eng Source Type: research

Potential new therapy with brain-on-a-chip axonal strain injury model
(World Scientific) Researchers from the Biomedical Engineering Department of Rutgers, The State University of New Jersey recently demonstrated the use of their 'Brain-on-a-Chip' microsystem to assess specific effects of traumatic axonal injury. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 17, 2014 Category: Global & Universal Source Type: news

Improving the catalytic potential and substrate tolerance of Gibberella intermedia nitrilase by whole-cell immobilization.
Abstract Comparative studies of immobilized and free cells of Gibberella intermedia CA3-1 in bioconversion of 3-cyanopyridine to nicotinic acid were performed. Entrapping method was chosen based on the advantages in enzymatic activity recovery, mechanical strength and preparation procedure. Four entrapment matrices were investigated and sodium alginate was screened to be the most suitable material. Maximal nitrilase activity of alginate immobilized cells was obtained under conditions of 2 % alginate, 0.6 % CaCl2, 0.4 g cell/g alginate, 1.8 mm bead size. The immobilized cells showed excellent substrate tolerance...
Source: Bioprocess and Biosystems Engineering - July 17, 2014 Category: Biomedical Engineering Authors: Li H, Yang T, Gong JS, Xiong L, Lu ZM, Li H, Shi JS, Xu ZH Tags: Bioprocess Biosyst Eng Source Type: research

Efficient utilization of cassava pulp for succinate production by metabolically engineered Escherichia coli KJ122.
Abstract A metabolically engineered Escherichia coli KJ122 was efficiently utilized for succinate production from cassava pulp during batch separate hydrolysis and fermentation (SHF) under simple anaerobic conditions. Succinate concentration of 41.46 ± 0.05 g/L with yield and productivity of 82.33 ± 0.14 g/100 g dry pulp and 0.84 ± 0.02 g/L/h was obtained. In batch simultaneous saccharification and fermentation (SSF), hydrolysis of 12 % (w/v) cassava pulp with an enzyme loading of 2 % AMG + 3 % Cel (v/w) at pH 6.5 was optimized at 39 °C. Succinate concentration of 80.86 ± 0.49 g/L with a yie...
Source: Bioprocess and Biosystems Engineering - July 17, 2014 Category: Biomedical Engineering Authors: Sawisit A, Jantama SS, Kanchanatawee S, Jantama K Tags: Bioprocess Biosyst Eng Source Type: research

Magnetic sensor for arterial distension and blood pressure monitoring.
Abstract A novel sensor for measuring arterial distension, pulse and pressure waveform is developed and evaluated. The system consists of a magnetic sensor which is applied and fixed to arterial vessels without any blood vessel constriction, hence avoiding stenosis. The measurement principle could be validated by in vitro experiments on silicone tubes, and by in vivo experiments in an animal model, thereby indicating the non-linear viscoelastic characteristics of real blood vessels. The sensor is capable to provide absolute measurements of the dynamically varying arterial diameter. By calibrating the sensor, a long...
Source: Biomedical Microdevices - July 16, 2014 Category: Biomedical Engineering Authors: Ruhhammer J, Herbstritt T, Ruh D, Foerster K, Heilmann C, Beyersdorf F, Goldschmidtboeing F, Seifert A, Woias P Tags: Biomed Microdevices Source Type: research

Analysis of particle size reduction on overall surface area and enzymatic hydrolysis yield of corn stover.
In this study, corn stover was milled and sieved into different size fractions from 1.42, 0.69, 0.34, to 0.21 mm, and the corresponding enzymatic hydrolysis yields were 24.69, 23.96, 25.34, and 26.97 %, respectively. The results indicate that the hydrolysis yield is approximately constant with changing corn stover particle sizes in the experimental range. The overall surface area and the inner pore size measurement show that the overall specific surface area was less than 2 % with the half reduction of particle size due to the greater inner pore surface area. The scanning electron microscope photographs gave direct evid...
Source: Bioprocess and Biosystems Engineering - July 16, 2014 Category: Biomedical Engineering Authors: Li H, Ye C, Liu K, Gu H, Du W, Bao J Tags: Bioprocess Biosyst Eng Source Type: research

Toxic influence of silver and uranium salts on activated sludge of wastewater treatment plants and synthetic activated sludge associates modeled on its pure cultures.
Abstract Toxic impact of silver and uranium salts on activated sludge of wastewater treatment facilities has been studied. Some dominating cultures (an active nitrogen fixer Agrobacterium tumifaciens (A.t) and micromyces such as Fusarium nivale, Fusarium oxysporum, and Penicillium glabrum) have been isolated and identified as a result of selection of the activated sludge microorganisms being steadiest under stressful conditions. For these cultures, the lethal doses of silver amounted 1, 600, 50, and 300 µg/l and the lethal doses of uranium were 120, 1,500, 1,000, and 1,000 mg/l, respectively. A.tumifaciens is sh...
Source: Bioprocess and Biosystems Engineering - July 16, 2014 Category: Biomedical Engineering Authors: Tyupa DV, Kalenov SV, Skladnev DA, Khokhlachev NS, Baurina MM, Kuznetsov AY Tags: Bioprocess Biosyst Eng Source Type: research

Early detection of abnormal left ventricular relaxation in acute myocardial ischemia with a quadratic model
This study investigates whether the relaxation curve can be better fitted with a “quadratic” model than with the “conventional” monoexponential model and if changes in the LV relaxation waveform due to acute myocardial ischemia could be better detected with the quadratic model. (Source: Medical Engineering and Physics)
Source: Medical Engineering and Physics - July 16, 2014 Category: Biomedical Engineering Authors: Philippe Morimont, Antoine Pironet, Thomas Desaive, Geoffrey Chase, Bernard Lambermont Source Type: research