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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 13.

Development of Penicillin G biosensor based on Penicillinase enzymes immobilized onto bio-chips.
Abstract Penicillin G (Pen-G) biosensor was developed by immobilizing penicillinase enzymes (Pen-X) onto tiny bio-chips using thioglycolic acid self-assembled monolayer (TGA-SAM). The selective pen-G biosensor was investigated by ferri/ferrocyanide couple using electrochemical method for catalytic hydrolysis of Pen-G/Pen-X in a very sensible approach. Pen-G was detected with modified bio-chip (Gold electrode of bio-chip/Thioglycolic acid/Penicillinase enzyme, in shortly AuE/TGA/Pen-X) by reliable cyclic voltammetric method at pH 7.1 in room conditions. The AuE/TGA/Pen-X modified bio-chip sensor demonstrates good ...
Source: Biomedical Microdevices - February 1, 2015 Category: Biomedical Engineering Authors: Rahman MM, Asiri AM Tags: Biomed Microdevices Source Type: research

Detection of GNAQ mutations and reduction of cell viability in uveal melanoma cells with functionalized gold nanoparticles.
CONCLUSION: AuNPs may in future be developed to serve as sensors for mutations of vital importance. The new release system for siRNA-AuNP improves previous systems, which conceivably will be useful for future therapeutic gene regulatory approaches. PMID: 25653058 [PubMed - in process] (Source: Biomedical Microdevices)
Source: Biomedical Microdevices - February 1, 2015 Category: Biomedical Engineering Authors: Posch C, Latorre A, Crosby MB, Celli A, Latorre A, Vujic I, Sanlorenzo M, Green GA, Weier J, Zekhtser M, Ma J, Monico G, Char DH, Jusufbegovic D, Rappersberger K, Somoza Á, Ortiz-Urda S Tags: Biomed Microdevices Source Type: research

Multi-electrode array capable of supporting precisely patterned hippocampal neuronal networks.
We present here the effective pretreatment methods, to improve cytocompatibility of cured thin SU-8 epoxy, commonly used in the fabrication of MEAs. The functionality of our novel MEA is proven by the successful recording of spontaneous and stimulated neuronal potentials from primary hippocampal neurons, including the propagation of evoked neuronal bursts between electrodes. PMID: 25653057 [PubMed - in process] (Source: Biomedical Microdevices)
Source: Biomedical Microdevices - February 1, 2015 Category: Biomedical Engineering Authors: Zhou T, Perry SF, Berdichevsky Y, Petryna S, Fluck V, Tatic-Lucic S Tags: Biomed Microdevices Source Type: research

A double-sided, single-chip integration scheme using through-silicon-via for neural sensing applications.
We present a new double-sided, single-chip monolithic integration scheme to integrate the CMOS circuits and MEMS structures by using through-silicon-via (TSV). Neural sensing applications were chosen as the implementation example. The proposed heterogeneous device integrates standard 0.18 μm CMOS technology, TSV and neural probe array into a compact single chip device. The neural probe array on the back-side of the chip is connected to the CMOS circuits on the front-side of the chip by using low-parasitic TSVs through the chip. Successful fabrication results and detailed characterization demonstrate the feasibility and p...
Source: Biomedical Microdevices - February 1, 2015 Category: Biomedical Engineering Authors: Chang CW, Chou LC, Huang PT, Wu SL, Lee SW, Chuang CT, Chen KN, Hwang W, Chen KH, Chiu CT, Tong HM, Chiou JC Tags: Biomed Microdevices Source Type: research

Microfluidic filtration and extraction of pathogens from food samples by hydrodynamic focusing and inertial lateral migration.
Abstract Detecting pathogenic bacteria in food or other biological samples with lab-on-a-chip (LOC) devices requires several sample preparation steps prior to analysis which commonly involves cleaning complex sample matrices of large debris. This often underestimated step is important to prevent these larger particles from clogging devices and to preserve initial concentrations when LOC techniques are used to concentrate or isolate smaller target microorganisms for downstream analysis. In this context, we developed a novel microfluidic system for membrane-free cleaning of biological samples from debris particles by...
Source: Biomedical Microdevices - February 1, 2015 Category: Biomedical Engineering Authors: Clime L, Hoa XD, Corneau N, Morton KJ, Luebbert C, Mounier M, Brassard D, Geissler M, Bidawid S, Farber J, Veres T Tags: Biomed Microdevices Source Type: research

Effect of bias voltage and temperature on lifetime of wireless neural interfaces with Al2O 3 and parylene bilayer encapsulation.
Abstract The lifetime of neural interfaces is a critical challenge for chronic implantations, as therapeutic devices (e.g., neural prosthetics) will require decades of lifetime. We evaluated the lifetime of wireless Utah electrode array (UEA) based neural interfaces with a bilayer encapsulation scheme utilizing a combination of alumina deposited by Atomic Layer Deposition (ALD) and parylene C. Wireless integrated neural interfaces (INIs), equipped with recording version 9 (INI-R9) ASIC chips, were used to monitor the encapsulation performance through radio-frequency (RF) power and telemetry. The wireless devices we...
Source: Biomedical Microdevices - February 1, 2015 Category: Biomedical Engineering Authors: Xie X, Rieth L, Caldwell R, Negi S, Bhandari R, Sharma R, Tathireddy P, Solzbacher F Tags: Biomed Microdevices Source Type: research

Controlled delivery of hollow corn protein nanoparticles via non-toxic crosslinking: in vivo and drug loading study.
Abstract In this research, controlled delivery of hollow nanoparticles from zein, the corn storage protein, to different organs of mice was achieved via crosslinking using citric acid, a non-toxic polycarboxylic acid derived from starch. Besides, crosslinking significantly enhanced water stability of nanoparticles while preserving their drug loading efficiency. Protein nanoparticles have been widely investigated as vehicles for delivery of therapeutics. However, protein nanoparticles were not stable in physiological conditions, easily cleared by mononuclear phagocyte system (MPS), and thus mainly accumulated and de...
Source: Biomedical Microdevices - February 1, 2015 Category: Biomedical Engineering Authors: Xu H, Shen L, Xu L, Yang Y Tags: Biomed Microdevices Source Type: research

A giant magnetoimpedance-based biosensor for sensitive detection of Escherichia coli O157:H7.
Abstract A giant magnetoimpedance (GMI)-based biosensor was developed for detection of Escherichia coli (E. coli) O157: H7. The GMI sensor involving the sensing elements of Cr/Cu/NiFe/Cu/NiFe was fabricated by Micro Electro-Mechanical system (MEMS) technology, including thick photoresist lithography and electroplating. A separate Au film substrate as immunoplatform was used to capture E. coli O157:H7. The monoclonal mouse anti-E. coli antibody was immobilized on Au film substrate surface with a self-assembled layer. The different concentration E. coli O157:H7 (100, 300 and 500 cfu/ml) were combined with Dynabeads-...
Source: Biomedical Microdevices - February 1, 2015 Category: Biomedical Engineering Authors: Yang Z, Sun XC, Wang T, Lei C, Liu Y, Zhou Y, Lei J Tags: Biomed Microdevices Source Type: research

Publisher's note.
Authors: PMID: 25663445 [PubMed - in process] (Source: Biomedical Microdevices)
Source: Biomedical Microdevices - February 1, 2015 Category: Biomedical Engineering Tags: Biomed Microdevices Source Type: research

In vivo imaging of microfluidic-produced microbubbles.
Abstract Microfluidics-based production of stable microbubbles for ultrasound contrast enhancement or drug/gene delivery allows for precise control over microbubble diameter but at the cost of a low production rate. In situ microfluidic production of microbubbles directly in the vasculature may eliminate the necessity for high microbubble production rates, long stability, or small diameters. Towards this goal, we investigated whether microfluidic-produced microbubbles directly administered into a mouse tail vein could provide sufficient ultrasound contrast. Microbubbles composed of nitrogen gas and stabilized with ...
Source: Biomedical Microdevices - February 1, 2015 Category: Biomedical Engineering Authors: Dhanaliwala AH, Dixon AJ, Lin D, Chen JL, Klibanov AL, Hossack JA Tags: Biomed Microdevices Source Type: research

Impedance characterization, degradation, and in vitro biocompatibility for platinum electrodes on BioMEMS.
Abstract Fine control of molecular transport through microfluidic systems can be obtained by modulation of an applied electrical field across channels with the use of electrodes. In BioMEMS designed for biological fluids and in vivo applications, electrodes must be biocompatible, biorobust and stable. In this work, the analysis and characterization of platinum (Pt) electrodes integrated on silicon substrates for biomedical applications are presented. Electrodes were incorporated on the surface of silicon chips by adhesion of laminated Pt foils or deposited at 30°, 45° or 90° angle by e-beam or physical vapor (sp...
Source: Biomedical Microdevices - February 1, 2015 Category: Biomedical Engineering Authors: Geninatti T, Bruno G, Barile B, Hood RL, Farina M, Schmulen J, Canavese G, Grattoni A Tags: Biomed Microdevices Source Type: research

Sensitivity analysis of geometric errors in additive manufacturing medical models
For many years additive manufacturing (AM) models have been used in medical applications such as surgical planning, teaching aids and simulations, customized surgical implants, prosthetics and orthotics [1–4], with many benefits for patients and healthcare professionals [5,6]. (Source: Medical Engineering and Physics)
Source: Medical Engineering and Physics - January 31, 2015 Category: Biomedical Engineering Authors: Jose Miguel Pinto, Cristobal Arrieta, Marcelo E. Andia, Sergio Uribe, Jorge Ramos-Grez, Alex Vargas, Pablo Irarrazaval, Cristian Tejos Tags: Technical Note Source Type: research

On the Impact of Intraluminal Thrombus Mechanical Behavior in AAA Passive Mechanics.
Abstract Intraluminal thrombus (ILT) is a pseudo-tissue that develops from coagulated blood, and is found in most abdominal aortic aneurysms (AAAs) of clinically relevant size. A number of studies have suggested that ILT mechanical characteristics may be related to AAA risk of rupture, even though there is still great controversy in this regard. ILT is isotropic and inhomogeneous and may appear as a soft (single-layered) or stiff (multilayered fibrotic) tissue. This paper aims to investigate how ILT constitution and topology influence the magnitude and location of peak wall stress (PWS). In total 21 patient-specifi...
Source: Annals of Biomedical Engineering - January 31, 2015 Category: Biomedical Engineering Authors: Riveros F, Martufi G, Gasser TC, Rodriguez-Matas JF Tags: Ann Biomed Eng Source Type: research

The Application of Three-Dimensional Printing in Animal Model of Augmentation Rhinoplasty.
In this study, we evaluated the feasibility of using 3D-printed polycaprolactone (PCL) scaffold seeded with fibrin/chondrocytes as a new dorsal augmentation material for rhinoplasty. The construct was surgically implanted on the nasal dorsum in the subperiosteal plane of six rabbits. The implants were harvested 4 and 12 weeks after implantation and evaluated by gross morphological assessment, radiographic imaging, and histologic examination. The initial shape of the implant was unchanged in all cases, and no definite post-operative complications were seen over the 3-month period. Radiologic evaluation confirmed that impla...
Source: Annals of Biomedical Engineering - January 31, 2015 Category: Biomedical Engineering Authors: Kim YS, Shin YS, Park DY, Choi JW, Park JK, Kim DH, Kim CH, Park SA Tags: Ann Biomed Eng Source Type: research

Coronary Flow Impacts Aortic Leaflet Mechanics and Aortic Sinus Hemodynamics.
Abstract Mechanical stresses on aortic valve leaflets are well-known mediators for initiating processes leading to calcific aortic valve disease. Given that non-coronary leaflets calcify first, it may be hypothesized that coronary flow originating from the ostia significantly influences aortic leaflet mechanics and sinus hemodynamics. High resolution time-resolved particle image velocimetry (PIV) measurements were conducted to map the spatiotemporal characteristics of aortic sinus blood flow and leaflet motion with and without physiological coronary flow in a well-controlled in vitro setup. The in vitro setup consi...
Source: Annals of Biomedical Engineering - January 31, 2015 Category: Biomedical Engineering Authors: Moore BL, Dasi LP Tags: Ann Biomed Eng Source Type: research

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(Source: IEEE Transactions on Signal Processing)
Source: IEEE Transactions on Signal Processing - January 30, 2015 Category: Biomedical Engineering Source Type: research

IEEE Signal Processing Society Information
(Source: IEEE Transactions on Signal Processing)
Source: IEEE Transactions on Signal Processing - January 30, 2015 Category: Biomedical Engineering Source Type: research

information for authors
(Source: IEEE Transactions on Signal Processing)
Source: IEEE Transactions on Signal Processing - January 30, 2015 Category: Biomedical Engineering Source Type: research

IEEE Transactions on Signal Processing Edics
(Source: IEEE Transactions on Signal Processing)
Source: IEEE Transactions on Signal Processing - January 30, 2015 Category: Biomedical Engineering Source Type: research

Table of Contents
(Source: IEEE Transactions on Signal Processing)
Source: IEEE Transactions on Signal Processing - January 30, 2015 Category: Biomedical Engineering Source Type: research

IEEE Transactions on Signal Processing publication information
(Source: IEEE Transactions on Signal Processing)
Source: IEEE Transactions on Signal Processing - January 30, 2015 Category: Biomedical Engineering Source Type: research

Front Cover
(Source: IEEE Transactions on Signal Processing)
Source: IEEE Transactions on Signal Processing - January 30, 2015 Category: Biomedical Engineering Source Type: research

[Front cover / Table of contents]
Presents the cover/table of contents for this issue of the periodical. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - January 30, 2015 Category: Biomedical Engineering Source Type: research

Model-based scale-up methodology for aerobic fed-batch bioprocesses: application to polyhydroxybutyrate (PHB) production.
Abstract This work presents a general model-based methodology to scale-up fed-batch bioprocesses. The idea behind this approach is to establish a dynamics hierarchy, based on a model of the process, that allows the designer to determine the proper scale factors as well as at which point of the fed-batch the process should be scaled up. Here, concepts and tools of linear control theory, such as the singular value decomposition of the Hankel matrix, are exploited in the context of process design. The proposed scale-up methodology is first described in a bioprocesses general framework highlighting its main features, k...
Source: Bioprocess and Biosystems Engineering - January 30, 2015 Category: Biomedical Engineering Authors: Monsalve-Bravo GM, Garelli F, Mozumder MS, Alvarez H, De Battista H Tags: Bioprocess Biosyst Eng Source Type: research

Optimization of variables affecting the direct transesterification of wet biomass from Nannochloropsis oceanica using ionic liquid as a co-solvent.
Abstract Ionic liquids have many applications, one of which entails their utilization as powerful solvents. In the present study, various experimental conditions of ionic liquid-mediated direct transesterification were investigated in terms of lipid-extracting ionic liquids, catalyst, reaction time, reaction temperature and volume of methanol to achieve effective FAME conversion with wet microalgal feedstock, Nannochloropsis oceanica. With ionic liquid, [Bmim][CF3SO3], highest fatty acid methyl ester (FAME) yield was shown. Among many experimental parameters, the two most critical factors to enhance FAME conversion...
Source: Bioprocess and Biosystems Engineering - January 30, 2015 Category: Biomedical Engineering Authors: Lee H, Shin WS, Jung JY, Kim CW, Lee JW, Kwon JH, Yang JW Tags: Bioprocess Biosyst Eng Source Type: research

Investigating the Dynamics of Supine Fluid Redistribution Within Multiple Body Segments Between Men and Women.
The objective of this study was to investigate the dynamics of rostral fluid shift in men and women. We developed a bioelectrical impedance system to measure leg, abdominal, thoracic and neck fluid volumes (LFV, AFV, TFV, NFV) continuously. Forty healthy non-obese adults (20 men) lay supine for 90 min while fluid volumes were measured. After 90 min, a similar volume of fluid shifted out of the legs in both sexes (p = 0.079), but men accumulated more fluid in their thorax (63 ± 6 vs. 44 ± 11 ml, p = 0.016) and neck (17 ± 2 vs. 14 ± 1 ml, p = 0.029) than women. In both sexes, the increase in NFV caused ...
Source: Annals of Biomedical Engineering - January 30, 2015 Category: Biomedical Engineering Authors: Yadollahi A, Singh B, Bradley TD Tags: Ann Biomed Eng Source Type: research

Diversity in the Strength and Structure of Unruptured Cerebral Aneurysms.
Abstract Intracranial aneurysms are pathological enlargements of brain arteries that are believed to arise from progressive wall degeneration and remodeling. Earlier work using classical histological approaches identified variability in cerebral aneurysm mural content, ranging from layered walls with intact endothelium and aligned smooth muscle cells, to thin, hypocellular walls. Here, we take advantage of recent advances in multiphoton microscopy, to provide novel results for collagen fiber architecture in 15 human aneurysm domes without staining or fixation as well as in 12 control cerebral arteries. For all aneu...
Source: Annals of Biomedical Engineering - January 30, 2015 Category: Biomedical Engineering Authors: Robertson AM, Duan X, Aziz KM, Hill MR, Watkins SC, Cebral JR Tags: Ann Biomed Eng Source Type: research

A Genetic Algorithm Based Multi-Objective Shape Optimization Scheme for Cementless Femoral Implant
The objective of this study was to develop a novel multi-objective custom-based shape optimization scheme for cementless femoral implant by integrating finite element (FE) analysis and a multi-objective genetic algorithm (GA). The FE model of a proximal femur was based on a subject-specific CT-scan dataset. Eighteen parameters describing the nature of four key sections of the implant were identified as design variables. Two objective functions, one based on implant-bone interface failure criterion, and the other based on resorbed proximal bone mass fraction (BMF), were formulated. The results predicted by the two objective...
Source: Journal of Biomechanical Engineering - January 29, 2015 Category: Biomedical Engineering Source Type: research

Computational Simulation of the Adaptive Capacity of Vein Grafts in Response to Increased Pressure
Vein maladaptation, leading to poor long-term patency, is a serious clinical problem in patients receiving coronary artery bypass grafts (CABGs) or undergoing related clinical procedures that subject veins to elevated blood flow and pressure. We propose a computational model of venous adaptation to altered pressure based on a constrained mixture theory of growth and remodeling (G&R). We identify constitutive parameters that optimally match biaxial data from a mouse vena cava, then numerically subject the vein to altered pressure conditions and quantify the extent of adaptation for a biologically reasonable set of bounds fo...
Source: Journal of Biomechanical Engineering - January 29, 2015 Category: Biomedical Engineering Source Type: research

Characterizing the Importance of Free Space in the Numerical Human Body Models
The geometric fidelity of the inner organs on finite-element model (FEM) of the human body and the choice to use discontinuous mesh engender the appearance of empty spaces that do not reflect the real-life situation of human body cavities. The aim of this study is to assess the influence of these empty spaces on the behavior of a simplified FEM built with three different structures in interaction which properties are relevant with the abdominal cavity. This FEM is made up of a large sphere (peritoneum) containing two hemispheres (liver and spleen). The space between peritoneum and inner organs was defined with two differen...
Source: Journal of Biomechanical Engineering - January 29, 2015 Category: Biomedical Engineering Source Type: research

Decreased Elastic Energy Storage, Not Increased Material Stiffness, Characterizes Central Artery Dysfunction in Fibulin-5 Deficiency Independent of Sex
Central artery stiffness has emerged over the past 15 years as a clinically significant indicator of cardiovascular function and initiator of disease. Loss of elastic fiber integrity is one of the primary contributors to increased arterial stiffening in aging, hypertension, and related conditions. Elastic fibers consist of an elastin core and multiple glycoproteins; hence defects in any of these constituents can adversely affect arterial wall mechanics. In this paper, we focus on mechanical consequences of the loss of fibulin-5, an elastin-associated glycoprotein involved in elastogenesis. Specifically, we compared the bia...
Source: Journal of Biomechanical Engineering - January 29, 2015 Category: Biomedical Engineering Source Type: research

A Thick-Walled Fluid–Solid-Growth Model of Abdominal Aortic Aneurysm Evolution: Application to a Patient-Specific Geometry
We propose a novel thick-walled fluid–solid-growth (FSG) computational framework for modeling vascular disease evolution. The arterial wall is modeled as a thick-walled nonlinearly elastic cylindrical tube consisting of two layers corresponding to the media-intima and adventitia, where each layer is treated as a fiber-reinforced material with the fibers corresponding to the collagenous component. Blood is modeled as a Newtonian fluid with constant density and viscosity; no slip and no-flux conditions are applied at the arterial wall. Disease progression is simulated by growth and remodeling (G&R) of the load bearing cons...
Source: Journal of Biomechanical Engineering - January 29, 2015 Category: Biomedical Engineering Source Type: research

Unidirectional Cell Crawling Model Guided by Extracellular Cues
Cell migration is a highly regulated and complex cellular process to maintain proper homeostasis for various biological processes. Extracellular environment was identified as the main affecting factors determining the direction of cell crawling. It was observed experimentally that the cell prefers migrating to the area with denser or stiffer array of microposts. In this article, an integrated unidirectional cell crawling model was developed to investigate the spatiotemporal dynamics of unidirectional cell migration, which incorporates the dominating intracellular biochemical processes, biomechanical processes and the prope...
Source: Journal of Biomechanical Engineering - January 29, 2015 Category: Biomedical Engineering Source Type: research

Simulation of Occupant Response in Space Capsule Landing Configurations With Suit Hardware
The purpose of this study was to compare the response of the total human model for safety (THUMS) human body finite element model (FEM) to experimental postmortem human subject (PMHS) test results and evaluate possible injuries caused by suit ring elements. Experimental testing evaluated the PMHS response in frontal, rear, side, falling, and spinal impacts. The THUMS was seated in a rigid seat that mirrored the sled buck used in the experimental testing. The model was then fitted with experimental combinations of neck, shoulder, humerus and thigh rings with a five-point restraint system. Experimental seat acceleration data...
Source: Journal of Biomechanical Engineering - January 29, 2015 Category: Biomedical Engineering Source Type: research

Immersive Visualization for Enhanced Computational Fluid Dynamics Analysis
We present a semi-automatic workflow for the import, processing, rendering, and stereoscopic visualization of high resolution, patient-specific imaging data, and CFD results in an IVE. Versatility of the workflow is highlighted with current clinical sequelae known to be influenced by adverse hemodynamics to illustrate potential clinical utility. (Source: Journal of Biomechanical Engineering)
Source: Journal of Biomechanical Engineering - January 29, 2015 Category: Biomedical Engineering Source Type: research

Assessing the Local Mechanical Environment in Medial Opening Wedge High Tibial Osteotomy Using Finite Element Analysis
This study demonstrates the benefits of using image-based FE modeling and bone theory to fine-tune HTO implant design. (Source: Journal of Biomechanical Engineering)
Source: Journal of Biomechanical Engineering - January 29, 2015 Category: Biomedical Engineering Source Type: research

Rotational Acceleration, Brain Tissue Strain, and the Relationship to Concussion
The mechanisms of concussion have been investigated by many researchers using a variety of methods. However, there remains much debate over the relationships between head kinematics from an impact and concussion. This review presents the links between research conducted in different disciplines to better understand the relationship between linear and rotational acceleration and brain strains that have been postulated as the root cause of concussion. These concepts are important when assigning performance variables for helmet development, car design, and protective innovation research. (Source: Journal of Biomechanical Engineering)
Source: Journal of Biomechanical Engineering - January 29, 2015 Category: Biomedical Engineering Source Type: research

Simulations Reveal Adverse Hemodynamics in Patients With Multiple Systemic to Pulmonary Shunts
In this study, we hypothesize that multiple shunts may lead to undesirable flow competition, resulting in increased residence time (RT) and elevated risk of thrombosis, as well as pulmonary overcirculation. Computational fluid dynamics-based multiscale simulations were performed to compare a range of shunt configurations and systematically quantify flow competition, pulmonary circulation, and other clinically relevant parameters. In total, 23 cases were evaluated by systematically changing the PDA/CS diameter, pulmonary vascular resistance (PVR), and MBTS position and compared by quantifying oxygen delivery (OD) to the sys...
Source: Journal of Biomechanical Engineering - January 29, 2015 Category: Biomedical Engineering Source Type: research

Enhanced Targeted Drug Delivery Through Controlled Release in a Three-Dimensional Vascular Tree
“Controlled particle release and targeting” is a technique using particle release score map (PRSM) and transient particle release score map (TPRSM) via backtracking to determine optimal drug injection locations for achieving an enhanced target efficiency (TE). This paper investigates the possibility of targeting desired locations through an idealized but complex three-dimensional (3D) vascular tree geometry under realistic hemodynamic conditions by imposing a Poiseuille velocity profile and a Womersley velocity profile derived from cine phase contrast magnetic resonance imaging (MRI) data for steady and pulsatile simul...
Source: Journal of Biomechanical Engineering - January 29, 2015 Category: Biomedical Engineering Source Type: research

New Editorial Board
Publication date: February 2015 Source:IRBM, Volume 36, Issue 1 Author(s): Maximilien Vermandel , Christine Toumoulin (Source: IRBM)
Source: IRBM - January 29, 2015 Category: Biomedical Engineering Source Type: research

Call for papers for a Special Issue on Medical Image Analysis for Computer Aided Diagnosis
Publication date: February 2015 Source:IRBM, Volume 36, Issue 1 Author(s): Khalifa Djemal , Su Ruan , Christine Toumoulin (Source: IRBM)
Source: IRBM - January 29, 2015 Category: Biomedical Engineering Source Type: research

NIRS-based classification of clench force and speed motor imagery with the use of empirical mode decomposition for BCI
This study aims to investigate the brain hemodynamic responses of clench force and speed motor imagery and extract task-relevant features to obtain better classification performance. Given the non-stationary characteristics of real hemodynamic measurements, empirical mode decomposition (EMD) was applied to reduce the physiological noise overwhelmed in the task-relevant NIRS signals. Compared with continuous wavelet decomposition, EMD does not require a pre-determined basis function. (Source: Medical Engineering and Physics)
Source: Medical Engineering and Physics - January 29, 2015 Category: Biomedical Engineering Authors: Xuxian Yin, Baolei Xu, Changhao Jiang, Yunfa Fu, Zhidong Wang, Hongyi Li, Gang Shi Source Type: research

Bioresorbable scaffolds for bone tissue engineering: Optimal design, fabrication, mechanical testing and scale-size effects analysis
Bone scaffolds for tissue regeneration require an optimal trade-off between biological and mechanical criteria. Optimal designs may be obtained using topology optimization (homogenization approach) and prototypes produced using additive manufacturing techniques. However, the process from design to manufacture remains a research challenge and will be a requirement of FDA design controls to engineering scaffolds. This work investigates how the design to manufacture chain affects the reproducibility of complex optimized design characteristics in the manufactured product. (Source: Medical Engineering and Physics)
Source: Medical Engineering and Physics - January 29, 2015 Category: Biomedical Engineering Authors: Pedro G. Coelho, Scott J. Hollister, Colleen L. Flanagan, Paulo R. Fernandes Source Type: research