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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 13.

Can a 15m-overground wheelchair sprint be used to assess wheelchair-specific anaerobic work capacity?
Abstract: Objective: To evaluate whether outcomes based on stopwatch time and power output (PO) over a 15m-overground wheelchair sprint test can be used to assess wheelchair-specific anaerobic work capacity, by studying their relationship with outcomes on a Wingate-based 30s-wheelchair ergometer sprint (WAnT).Methods: Able-bodied persons (N=19, 10 men, aged 18–26y) performed a 15m overground sprint test in an instrumented wheelchair and a WAnT. 15m-outcomes were based on stopwatch time (time and mean velocity over 15m) and on PO (primary outcome: highest mean unilateral PO over successive 5s-intervals (P5-15m)). WAnT-out...
Source: Medical Engineering and Physics - February 18, 2014 Category: Biomedical Engineering Authors: Jan W. van der Scheer, Sonja de Groot, Riemer J.K. Vegter, DirkJan (H.E.J.) Veeger, Lucas H.V. van der Woude Tags: Papers Source Type: research

A geometric scaling model for assessing the impact of aneurysm size ratio on hemodynamic characteristics
Background: The intracranial aneurysm (IA) size has been proved to have impacts on the hemodynamics and can be applied for the prediction of IA rupture risk. Although the relationship between aspect ratio and hemodynamic parameters was investigated using real patients and virtual models, few studies focused on longitudinal experiments of IAs based on patient-specific aneurysm models. We attempted to do longitudinal simulation experiments of IAs by developing a series of scaled models. Methods: In this work, a novel scaling approach was proposed to create IA models with different aneurysm size ratios (ASRs) defined as IA he...
Source: BioMedical Engineering OnLine - February 17, 2014 Category: Biomedical Engineering Authors: Yunling LongHongyu YuZhizheng ZhuoYing ZhangYang WangXinjian YangHaiyun Li Source Type: research

Automatic online detection of atrial fibrillation based on symbolic dynamics and Shannon entropy
Conclusions: Overall, in contrast to the other available techniques, the test results indicate that the newly developed approach outperforms traditional methods using these databases under assessed various experimental situations, and suggest our technique could be of practical use for clinicians in the future. (Source: BioMedical Engineering OnLine)
Source: BioMedical Engineering OnLine - February 17, 2014 Category: Biomedical Engineering Authors: Xiaolin ZhouHongxia DingBenjamin UngEmma Pickwell-MacPhersonYuanting Zhang Source Type: research

An orthotropic viscoelastic material model for passive myocardium: theory and algorithmic treatment.
Abstract This contribution presents a novel constitutive model in order to simulate an orthotropic rate-dependent behaviour of the passive myocardium at finite strains. The motivation for the consideration of orthotropic viscous effects in a constitutive level lies in the disagreement between theoretical predictions and experimentally observed results. In view of experimental observations, the material is deemed as nearly incompressible, hyperelastic, orthotropic and viscous. The viscoelastic response is formulated by means of a rheological model consisting of a spring coupled with a Maxwell element in parallel. In...
Source: Computer Methods in Biomechanics and Biomedical Engineering - February 17, 2014 Category: Biomedical Engineering Authors: Cansız FB, Dal H, Kaliske M Tags: Comput Methods Biomech Biomed Engin Source Type: research

Numerical simulation of fluid-structure interaction in bypassed DeBakey III aortic dissection.
Abstract It was found that bypass graft alone could achieve great effects in treating aortic dissection. In order to investigate the mechanical mechanism and the haemodynamic validity of the bypassing treatment for DeBakey III aortic dissection, patient-specific models of DeBakey III aortic dissection treated with different bypassing strategies were constructed. One of the bypassing strategies is bypassing between ascending aorta and abdominal aorta, and the other is bypassing between left subclavian artery and abdominal aorta. Numerical simulations under physiological flow conditions based on fluid-structure inter...
Source: Computer Methods in Biomechanics and Biomedical Engineering - February 17, 2014 Category: Biomedical Engineering Authors: Qiao A, Yin W, Chu B Tags: Comput Methods Biomech Biomed Engin Source Type: research

Liquid perfluorochemical-supported hybrid cell culture system for proliferation of chondrocytes on fibrous polylactide scaffolds.
Abstract CP5 bovine chondrocytes were cultured on biodegradable electrospun fibrous polylactide (PLA) scaffolds placed on a flexible interface formed between two immiscible liquid phases: (1) hydrophobic perfluorochemical (PFC) and (2) aqueous culture medium, as a new way of cartilage implant development. Robust and intensive growth of CP5 cells was achieved in our hybrid liquid-solid-liquid culture system consisting of the fibrous PLA scaffolds in contrast to limited growth of the CP5 cells in traditional culture system with PLA scaffold placed on solid surface. The multicellular aggregates of CP5 cells covered th...
Source: Bioprocess and Biosystems Engineering - February 16, 2014 Category: Biomedical Engineering Authors: Pilarek M, Grabowska I, Senderek I, Wojasiński M, Janicka J, Janczyk-Ilach K, Ciach T Tags: Bioprocess Biosyst Eng Source Type: research

Erratum to: Universal hydrophilic coating of thermoplastic polymers currently used in microfluidics.
PMID: 24526363 [PubMed - as supplied by publisher] (Source: Biomedical Microdevices)
Source: Biomedical Microdevices - February 15, 2014 Category: Biomedical Engineering Authors: Zilio C, Sola L, Damin F, Faggioni L, Chiari M Tags: Biomed Microdevices Source Type: research

Scaffold-Free Tissue Engineering: Organization of the Tissue Cytoskeleton and Its Effects on Tissue Shape.
Abstract Work described herein characterizes tissues formed using scaffold-free, non-adherent systems and investigates their utility in modular approaches to tissue engineering. Immunofluorescence analysis revealed that all tissues formed using scaffold-free, non-adherent systems organize tissue cortical cytoskeletons that appear to be under tension. Tension in these tissues was also evident when modules (spheroids) were used to generate larger tissues. Real-time analysis of spheroid fusion in unconstrained systems illustrated modular motion that is compatible with alterations in tensions, due to the process of dis...
Source: Annals of Biomedical Engineering - February 15, 2014 Category: Biomedical Engineering Authors: Czajka CA, Mehesz AN, Trusk TC, Yost MJ, Drake CJ Tags: Ann Biomed Eng Source Type: research

Flexible Codebook Design for Limited Feedback Systems Via Sequential Smooth Optimization on the Grassmannian Manifold
Grassmannian quantization codebooks play a central role in a number of limited feedback schemes for single and multi-user multiple-input multiple-output (MIMO) communication systems. In practice, it is often desirable that these codebooks possess additional properties that facilitate their implementation, beyond the provision of good quantization performance. Although some good codebooks exist, their design tends to be a rather intricate task. The goal of this paper is to suggest a flexible approach to the design of Grassmannian codebooks based on sequential smooth optimization on the Grassmannian manifold and the use of s...
Source: IEEE Transactions on Signal Processing - February 14, 2014 Category: Biomedical Engineering Source Type: research

Joint Power and Antenna Selection Optimization in Large Cloud Radio Access Networks
Large multiple-input multiple-output (MIMO) networks promise high energy efficiency, i.e., much less power is required to achieve the same capacity compared to the conventional MIMO networks if perfect channel state information (CSI) is available at the transmitter. However, in such networks, huge overhead is required to obtain full CSI especially for Frequency-Division Duplex (FDD) systems. To reduce overhead, we propose a downlink antenna selection scheme, which selects $S$ antennas from $M > S$ transmit antennas based on the large scale fading to serve $Kleq S$ users in large distributed MIMO networks employing regulari...
Source: IEEE Transactions on Signal Processing - February 14, 2014 Category: Biomedical Engineering Source Type: research

On Forward Channel Estimation for MIMO Precoding in Cooperative Relay Wireless Transmission Systems
Linear precoding for wireless multi-input multi-output (MIMO) transceivers has demonstrated substantial strength in cooperative relay networks for achieving high system throughput and performance. However, traditional precoder optimization critically assumes knowledge of channel state information (CSI) at source nodes. For linear MIMO source precoding design, we propose a novel method to estimate the quadratic product of forward-link channel information between source and relay nodes. To conserve bandwidth, our source estimates the forward-link MIMO CSI by utilizing inherent signals transmitted by amplify-and-forward (AF) ...
Source: IEEE Transactions on Signal Processing - February 14, 2014 Category: Biomedical Engineering Source Type: research

Optimum Compression of a Noisy Measurement for Transmission Over a Noisy Channel
This paper is motivated by sensing and wireless communication, where data compression or dimension reduction may be used to reduce the required communication bandwidth. High-dimensional measurements are converted into low-dimensional representations through linear compression. Our aim is to compress a noisy sensor measurement, allowing for the fact that the compressed measurement will then be transmitted over a noisy channel. We give the closed-form expression for the optimal compression matrix that minimizes the trace or determinant of the error covariance matrix. We show that the solutions share a common architecture con...
Source: IEEE Transactions on Signal Processing - February 14, 2014 Category: Biomedical Engineering Source Type: research

Rate Switching Filters: Model and Efficient Approximation
A filter model is proposed, allowing for the realization of a digital structure that computes a decimated version of the output signal. Each time the sampling rate is switched, pre-calculated coefficients are loaded by the processor in parallel to computing a filter state that fits the new rate. Sufficient conditions for the existence of the new state are given: holding these conditions, the sampling rate can be varied at runtime without introducing spurious transients in the output signal. The equivalence between the proposed filter model and existing polyphase networks for the efficient computation of decimated signals i...
Source: IEEE Transactions on Signal Processing - February 14, 2014 Category: Biomedical Engineering Source Type: research

Sequential Monte Carlo Methods for State and Parameter Estimation in Abruptly Changing Environments
This paper develops a novel sequential Monte Carlo (SMC) approach for joint state and parameter estimation that can deal efficiently with abruptly changing parameters which is a common case when tracking maneuvering targets. The approach combines Bayesian methods for dealing with change-points with methods for estimating static parameters within the SMC framework. The result is an approach that adaptively estimates the model parameters in accordance with changes to the target's trajectory. The developed approach is compared against the Interacting Multiple Model (IMM) filter for tracking a maneuvering target over a complex...
Source: IEEE Transactions on Signal Processing - February 14, 2014 Category: Biomedical Engineering Source Type: research

Analysis of the Gradient-Descent Total Least-Squares Adaptive Filtering Algorithm
The gradient-descent total least-squares (GD-TLS) algorithm is a stochastic-gradient adaptive filtering algorithm that compensates for error in both input and output data. We study the local convergence of the GD-TLS algoritlun and find bounds for its step-size that ensure its stability. We also analyze the steady-state performance of the GD-TLS algorithm and calculate its steady-state mean-square deviation. Our steady-state analysis is inspired by the energy-conservation-based approach to the performance analysis of adaptive filters. The results predicted by the analysis show good agreement with the simulation experiments...
Source: IEEE Transactions on Signal Processing - February 14, 2014 Category: Biomedical Engineering Source Type: research

Designing Unimodular Codes Via Quadratic Optimization
The NP-hard problem of optimizing a quadratic form over the unimodular vector set arises in radar code design scenarios as well as other active sensing and communication applications. To tackle this problem (which we call unimodular quadratic program (UQP)), several computational approaches are devised and studied. Power method-like iterations are introduced for local optimization of UQP. Furthermore, a monotonically error-bound improving technique (MERIT) is proposed to obtain the global optimum or a local optimum of UQP with good sub-optimality guarantees. The provided sub-optimality guarantees are case-dependent and may...
Source: IEEE Transactions on Signal Processing - February 14, 2014 Category: Biomedical Engineering Source Type: research

Cross-Layer MIMO Transceiver Optimization for Multimedia Streaming in Interference Networks
We consider dynamic precoder/decorrelator optimization for multimedia streaming in MIMO interference networks. We propose a truly cross-layer framework in the sense that the optimization objective is the application level performance metrics for multimedia streaming, namely the playback interruption and buffer overflow probabilities. The optimization variables are the MIMO precoders/decorrelators at the transmitters and the receivers, which are adaptive to both the instantaneous channel condition and the playback queue length. The problem is a challenging multi-dimensional stochastic optimization problem and brute-force so...
Source: IEEE Transactions on Signal Processing - February 14, 2014 Category: Biomedical Engineering Source Type: research

On Meeting the Peak Correlation Bounds
In this paper, we study the problem of meeting peak periodic or aperiodic correlation bounds for complex-valued sets of sequences. To this end, the Welch, Levenstein, and Exponential bounds on the peak inner-product of sequence sets are considered and used to provide compound peak correlation bounds in both periodic and aperiodic cases. The peak aperiodic correlation bound is further improved by using the intrinsic dimension deficiencies associated with its formulation. In comparison to the compound bound, the new aperiodic bound contributes an improvement of more than 35% for some specific values of the sequence length $n...
Source: IEEE Transactions on Signal Processing - February 14, 2014 Category: Biomedical Engineering Source Type: research

Table of contents
Presents the table of contents for this issue of the periodical. (Source: IEEE Transactions on Signal Processing)
Source: IEEE Transactions on Signal Processing - February 14, 2014 Category: Biomedical Engineering Source Type: research

Transformation of aromatic dyes using green synthesized silver nanoparticles.
Abstract Nowadays, increasing use of nanoproducts in area of human and environmental applications raises concern about safety aspects of nanoparticles synthesized using traditional physicochemical methods. Silver nanoparticles (AgNPs) synthesis at ambient parameters using latex of medicinally important plant Jatropha gossypifolia (J. gossypifolia) is reported in the present study. Potential of AgNPs in degradation of methylene blue and eosin B was also evaluated. Rapid formation of stable AgNPs was analyzed by visual color change from colorless to yellow-red after addition of latex in AgNO3 solution and by characte...
Source: Bioprocess and Biosystems Engineering - February 14, 2014 Category: Biomedical Engineering Authors: Borase HP, Patil CD, Salunkhe RB, Suryawanshi RK, Salunke BK, Patil SV Tags: Bioprocess Biosyst Eng Source Type: research

Process optimization for increased yield of surface-expressed protein in Escherichia coli.
Abstract The autotransporter family of Gram-negative protein exporters has been exploited for surface expression of recombinant passenger proteins. While the passenger in some cases was successfully translocated, a major problem has been low levels of full-length protein on the surface due to proteolysis following export over the cytoplasmic membrane. The aim of the present study was to increase the surface expression yield of the model protein SefA, a Salmonella enterica fimbrial subunit with potential for use in vaccine applications, by reducing this proteolysis through process design using Design of Experiments ...
Source: Bioprocess and Biosystems Engineering - February 14, 2014 Category: Biomedical Engineering Authors: Jarmander J, Janoschek L, Lundh S, Larsson G, Gustavsson M Tags: Bioprocess Biosyst Eng Source Type: research

Marine algae-mediated synthesis of gold nanoparticles using a novel Ecklonia cava.
Abstract In the present study, we report rapid biological synthesis of gold nanoparticles (Au NPs) using a novel marine brown alga Ecklonia cava (Family: Lessoniaceae) by the reduction of chloroauric acid. The formation of Au NPs reaction was complete within 1 min at 80 °C and physiochemically characterized with different analytical techniques. FTIR spectroscopy revealed that Au NPs were functionalized with biomolecules that have primary amine group, hydroxyl group and other stabilizing functional groups. X-ray diffraction pattern showed high purity and face-centered cubic structure of Au NPs. Microscopy results...
Source: Bioprocess and Biosystems Engineering - February 14, 2014 Category: Biomedical Engineering Authors: Venkatesan J, Manivasagan P, Kim SK, Kirthi AV, Marimuthu S, Rahuman AA Tags: Bioprocess Biosyst Eng Source Type: research

Scale-down effect on the extracellular proteome of Escherichia coli: correlation with membrane permeability and modulation according to substrate heterogeneities.
Abstract Protein leakage is induced in well-mixed fed-batch bioreactor by comparison with cultures carried out in scale-down conditions. This effect is attributed to a progressive increase of cell membrane permeability and the synthesis of several outer-membrane components allowing to cope with substrate limitation commonly found in high cell density culture. A comparative analysis of protein leakage has thus been performed in well-mixed bioreactors and in scale-down devices. The extracellular proteome of E.coli has been investigated by 2D-gel electrophoresis and identified by subsequent MALDI-TOF analysis. On 110 ...
Source: Bioprocess and Biosystems Engineering - February 14, 2014 Category: Biomedical Engineering Authors: Brognaux A, Francis F, Twizere JC, Thonart P, Delvigne F Tags: Bioprocess Biosyst Eng Source Type: research

Using polyethylene glycol as nonionic osmoticum to promote growth and lipid production of marine microalgae Nannochloropsis oculata.
In this study, 0.5 % (w/v) PEG-20000 (Π = 2.466 MPa) remarkably enhanced microalgal growth without interference of intracellular lipid productivity and cellular size, yielding >50 % (w/w) increases in biomass, total lipid, and eicosapentaenoic acid amounts after 7 days that provided the optimal condition for microalgal cultivation. These positive effects possibly resulted from the moderate enhancement of osmotic stress in the medium and stronger chaotrope-like behavior from higher molecular weight PEG. With further verification that 0.5 % (w/v) PEG-20000 enabled to reduce the effect of oxygen inhibition on micro...
Source: Bioprocess and Biosystems Engineering - February 13, 2014 Category: Biomedical Engineering Authors: Lee YH, Yeh YL Tags: Bioprocess Biosyst Eng Source Type: research

Production of citric acid using its extraction wastewater treated by anaerobic digestion and ion exchange in an integrated citric acid-methane fermentation process.
Abstract In order to solve the problem of extraction wastewater pollution in citric acid industry, an integrated citric acid-methane fermentation process is proposed in this study. Extraction wastewater was treated by mesophilic anaerobic digestion and then used to make mash for the next batch of citric acid fermentation. The recycling process was done for seven batches. Citric acid production (82.4 g/L on average) decreased by 34.1 % in the recycling batches (2nd-7th) compared with the first batch. And the residual reducing sugar exceeded 40 g/L on average in the recycling batches. Pigment substances, acetic aci...
Source: Bioprocess and Biosystems Engineering - February 13, 2014 Category: Biomedical Engineering Authors: Xu J, Chen YQ, Zhang HJ, Tang L, Wang K, Zhang JH, Chen XS, Mao ZG Tags: Bioprocess Biosyst Eng Source Type: research

On Efficient Design of High-Order Filters With Applications to Filter Banks and Transmultiplexers With Large Number of Channels
This paper proposes a method for designing high-order linear-phase finite-length impulse response (FIR) filters which are required as, e.g., the prototype filters in filter banks (FBs) and transmultiplexers (TMUXs) with a large number of channels. The proposed method uses the Farrow structure to express the polyphase components of the desired filter. Thereby, the only unknown parameters, in the filter design, are the coefficients of the Farrow subfilters. The number of these unknown parameters is considerably smaller than that of the direct filter design methods. Besides these unknown parameters, the proposed method needs ...
Source: IEEE Transactions on Signal Processing - February 12, 2014 Category: Biomedical Engineering Source Type: research

Decentralized Dynamic Optimization Through the Alternating Direction Method of Multipliers
This paper develops the application of the alternating direction method of multipliers (ADMM) to optimize a dynamic objective function in a decentralized multi-agent system. At each time slot, agents in the network observe local functions and cooperate to track the optimal time-varying argument of the sum objective. This cooperation is based on maintaining local primal variables that estimate the value of the optimal argument and auxiliary dual variables that encourage proximity with neighboring estimates. Primal and dual variables are updated by an ADMM iteration that can be implemented in a distributed manner whereby loc...
Source: IEEE Transactions on Signal Processing - February 12, 2014 Category: Biomedical Engineering Source Type: research

Distributed Source-Channel Coding Based on Real-Field BCH Codes
We use real-number codes to compress statistically dependent sources and establish a new framework for distributed lossy source coding in which we compress sources before, rather than after, quantization. This change in the order of binning and quantization blocks makes it possible to model the correlation between continuous-valued sources more realistically and compensate for the quantization error partially. We then focus on the asymmetric case, i.e., lossy source coding with side information at the decoder. The encoding and decoding procedures are described in detail for a class of real-number codes called discrete Four...
Source: IEEE Transactions on Signal Processing - February 12, 2014 Category: Biomedical Engineering Source Type: research

MMSE Design of Time and Color Multiplexing Codes
Illumination multiplexing has proven itself to be a valuable tool in image quality improvement for many computer vision and graphics applications, provided that its limitations on photon noise and saturation are properly tackled. Currently, multiplexing codes are constructed according to the maximum signal-to-noise ratio (SNR), and they are primarily employed for time multiplexing, a technique that requires the number of measurements $M$to be equal to the number of illumination sources $N$. In this work, we propose an illumination multiplexing method based on minimum mean square errors (MMSEs) for the more general setting ...
Source: IEEE Transactions on Signal Processing - February 12, 2014 Category: Biomedical Engineering Source Type: research

Adaptive Bayesian Denoising for General Gaussian Distributed Signals
We study behavior of the Bayesian estimator for noisy General Gaussian Distributed (GGD) data and show that this estimator can be well estimated with a simple shrinkage function. The four parameters of this shrinkage function are functions of GGD's shape parameter and data variance. The Shrinkage map, denoted by Rigorous BayesShrink (R-BayesShrink), models the Bayesian estimator for any value of shape parameter. In addition, when the shape parameter is between 0.5 and 1, this Shrinkage function transforms into a simple soft threshold. This result places the role of soft thresholding image denoising methods, such as BayesSk...
Source: IEEE Transactions on Signal Processing - February 12, 2014 Category: Biomedical Engineering Source Type: research

Near-Optimal Sensor Placement for Linear Inverse Problems
A classic problem is the estimation of a set of parameters from measurements collected by only a few sensors. The number of sensors is often limited by physical or economical constraints and their placement is of fundamental importance to obtain accurate estimates. Unfortunately, the selection of the optimal sensor locations is intrinsically combinatorial and the available approximation algorithms are not guaranteed to generate good solutions in all cases of interest. We propose FrameSense, a greedy algorithm for the selection of optimal sensor locations. The core cost function of the algorithm is the frame potential, a sc...
Source: IEEE Transactions on Signal Processing - February 12, 2014 Category: Biomedical Engineering Source Type: research

A Frequency-Locked-Loop Filter for Biased Multi-Sinusoidal Estimation
In this paper, an adaptive filter, based on a third-order generalized integrator, is proposed to estimate all the parameters of a biased sinusoid. The averaging theory is used to prove that the filter identifies the unknown frequency of the signal, in the case of a pure biased sinusoid in input. Moreover, in the case of a generic periodic signal, the method provides an estimate of the fundamental frequency by converging to a limit cycle in its vicinity. The robustness of the proposed approach with respect to noise in the input signal is analyzed. A filter bank is also presented to deal with the reconstruction problem of a ...
Source: IEEE Transactions on Signal Processing - February 12, 2014 Category: Biomedical Engineering Source Type: research

Simultaneous Low-Pass Filtering and Total Variation Denoising
This paper seeks to combine linear time-invariant (LTI) filtering and sparsity-based denoising in a principled way in order to effectively filter (denoise) a wider class of signals. LTI filtering is most suitable for signals restricted to a known frequency band, while sparsity-based denoising is suitable for signals admitting a sparse representation with respect to a known transform. However, some signals cannot be accurately categorized as either band-limited or sparse. This paper addresses the problem of filtering noisy data for the particular case where the underlying signal comprises a low-frequency component and a spa...
Source: IEEE Transactions on Signal Processing - February 12, 2014 Category: Biomedical Engineering Source Type: research

Special Section: Cognitive and Affective Processes in Multimedia Learning
Learning and Instruction, Volume 29, (February 2014) Edited by (Source: Elsevier Updates: Engineering)
Source: Elsevier Updates: Engineering - February 12, 2014 Category: Biomedical Engineering Source Type: news

A stochastic filtering approach to recover strain images from quasi-static ultrasound elastography
Conclusions: The potential of our algorithm is to provide the distribution of mechanically meaningful strain under a proper biomechanical model constraint. We address the model-data discrepancy and measurement noise by introducing process noise and measurement noise in our framework, and then the mechanically meaningful strain is estimated through the Kalman filter in the minimum mean square error (MMSE)sense. (Source: BioMedical Engineering OnLine)
Source: BioMedical Engineering OnLine - February 12, 2014 Category: Biomedical Engineering Authors: Minhua LuDan WuWan-hua LinWeifang LiHeye ZhangWenHua Huang Source Type: research

Optimization and robustness analysis of hybridoma cell fed-batch cultures using the overflow metabolism model.
Abstract The maximization of biomass productivity in fed-batch cultures of hybridoma cells is analyzed based on the overflow metabolism model. Due to overflow metabolism, often attributed to limited oxygen capacity, lactate and ammonia are formed when the substrate concentrations (glucose and glutamine) are above a critical value, which results in a decrease in biomass productivity. Optimal feeding rate, on the one hand, for a single feed stream containing both glucose and glutamine and, on the other hand, for two separate feed streams of glucose and glutamine are determined using a Nelder-Mead simplex optimization...
Source: Bioprocess and Biosystems Engineering - February 12, 2014 Category: Biomedical Engineering Authors: Amribt Z, Dewasme L, Vande Wouwer A, Bogaerts P Tags: Bioprocess Biosyst Eng Source Type: research

Implementation and validation of thoracic side impact injury prediction metrics in a human body model.
This study's purpose was to implement injury metrics into the Total Human Model for Safety (THUMS) mirroring the spinal accelerometers, rib accelerometers and chest band instrumentation from two lateral post-mortem human subject sled test configurations. In both sled configurations, THUMS contacted a flat rigid surface (either a wall or beam) at 6.7 m/s. Sled A maximum simulated wall forces for the thorax, abdomen and pelvis were 7.1, 5.0 and 10.0 kN versus 5.7 ± 0.8, 3.4 ± 1.2 and 6.2 ± 2.7 kN experimentally. Sled B maximum simulated beam forces for the torso and pelvis were 8.0 and 7.6 kN versus 8.5 ± 0.2...
Source: Computer Methods in Biomechanics and Biomedical Engineering - February 12, 2014 Category: Biomedical Engineering Authors: Golman AJ, Danelson KA, Gaewsky JP, Stitzel JD Tags: Comput Methods Biomech Biomed Engin Source Type: research

A Novel Testing Platform for Assessing Knee Joint Mechanics: A Parallel Robotic System Combined with an Instrumented Spatial Linkage.
Abstract Assessing joint function following trauma and its inter-relation with degenerative changes requires an understanding of the normal state of structural loading in the joint. Very few studies have attempted to reproduce joint specific in vivo motions in vitro to quantify the actual loads carried by different tissues within the knee joint. The most significant challenge in this area is the very high sensitivity of the loads in joint structures to motion reproduction accuracy. A novel testing platform for assessing knee joint mechanics is described, comprised of a highly accurate (0.3 ± 0.1 mm, 0.3 ± 0....
Source: Annals of Biomedical Engineering - February 12, 2014 Category: Biomedical Engineering Authors: Atarod M, Rosvold JM, Frank CB, Shrive NG Tags: Ann Biomed Eng Source Type: research

Review of "Adaptive Optics for Biological Imaging" edited by Joel A. Kubby
This article is a review of the book "Adaptive Optics for Biological Imaging", edited by Joel A. Kubby and published by CRC Press. The book provides an introduction to the defining concepts and implementation aspects of adaptive optics in field of microscopy. In addition, it presents state-of-the-art applications of this technique, which dramatically improves the performance of imaging devices. (Source: BioMedical Engineering OnLine)
Source: BioMedical Engineering OnLine - February 11, 2014 Category: Biomedical Engineering Authors: Gaspard Duchêne Source Type: research

Review of ¿Adaptive Optics for Biological Imaging¿ edited by Joel A. Kubby
This article is a review of the book "Adaptive Optics for Biological Imaging", edited by Joel A. Kubby and published by CRC Press. The book provides an introduction to the defining concepts and implementation aspects of adaptive optics in field of microscopy. In addition, it presents state-of-the-art applications of this technique, which dramatically improves the performance of imaging devices. (Source: BioMedical Engineering OnLine)
Source: BioMedical Engineering OnLine - February 11, 2014 Category: Biomedical Engineering Authors: Gaspard Duchêne Source Type: research