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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 13.

Winship Cancer Center researchers get $3.5M NCI award
The National Cancer Institute gave two researchers at Emory University’s Winship Cancer Center a total of $3.5 award for their work in informatics technology. Dr. David Gutman and Lee Cooper, assistant professors in the departments of Neurology, Biomedical Informatics and Biomedical Engineering, won the Informatics Technology for Cancer Research (ITCR) U24 award for their work, which is focused on digital microscopy images of tissue slides that have traditionally been used by pathologists for… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - May 4, 2015 Category: Pharmaceuticals Authors: Ellie Hensley Source Type: news

What are the most popular topics of CMPB in the past 3 years?
Computer Methods and Programs in Biomedicine (CMPB), since its inception in 1970, existed for more than 45 years. Over last three years, CMPB has published 658 papers (2012:219, 2013:221, 2014:216). Types of papers were classified original papers (602), special issues (44), editorial materials (8) and review papers (4). These all papers are covering different categories such as computer science, biomedical engineering, medical informatics and so on. We would like to aware the readers with keywords which appeared most frequently in that are the papers published in the past three years and their visualization would make it e...
Source: Computer Methods and Programs in Biomedicine - May 4, 2015 Category: Bioinformatics Authors: Hsuan-Chia Yang, Usman Iqbal, Yu-Chuan (Jack) Li Tags: Editorial Source Type: research

Enzymatic synthesis of isoamyl butyrate catalyzed by immobilized lipase on poly-methacrylate particles: optimization, reusability and mass transfer studies.
Abstract Isoamyl butyrate (banana flavor) was synthesized by esterification reaction of isoamyl alcohol and butyric acid in heptane medium. Immobilized Thermomyces lanuginosus lipase (TLL) prepared via physical adsorption on mesoporous poly-methacrylate particles (PMA) was used as biocatalyst. The factors that affect the esterification reaction were optimized by response surface methodology (RSM). Under optimal experimental conditions, maximum ester conversion percentage of 96.1 and 73.6 % was reached after 50 and 90 min, respectively, for esterification reaction performed at equimolar ratio alcohol:acid at 500 a...
Source: Bioprocess and Biosystems Engineering - May 3, 2015 Category: Biomedical Engineering Authors: Todero LM, Bassi JJ, Lage FA, Corradini MC, Barboza JC, Hirata DB, Mendes AA Tags: Bioprocess Biosyst Eng Source Type: research

Detection of an amphiphilic biosample in a paper microchannel based on length.
Abstract We developed a simple method to achieve semiquantitative detection of an amphiphilic biosample through measuring the length of flow on a microfluidic analytical device (μPAD) based on paper. When an amphiphilic sample was dripped into a straight microchannel defined with a printed wax barrier (hydrophobic) on filter paper (hydrophilic), the length of flow was affected by the reciprocal effect between the sample, the filter-paper channel and the wax barrier. The flow length decreased with increasing concentration of an amphiphilic sample because of adsorption of the sample on the hydrophobic barrier. Measu...
Source: Biomedical Microdevices - May 1, 2015 Category: Biomedical Engineering Authors: Chen YT, Yang JT Tags: Biomed Microdevices Source Type: research

Detection of Dependent Heavy-Tailed Signals
This paper examines the problem of detection of dependent $alpha$-stable signals. Measurements of several phenomena exhibit non-Gaussian, heavy-tailed behavior in their probability density functions (p.d.f.); we use the class of $alpha$ -stable distributions to characterize these signals. When two sensors make simultaneous measurements of such phenomena, these heavy-tailed realizations are dependent across sensors. The intersensor dependence is modeled using copulas. We consider a two-sided test in the Neyman–Pearson framework and present an asymptotic analysis of the generalized likelihood test (GLRT). Both, nested...
Source: IEEE Transactions on Signal Processing - May 1, 2015 Category: Biomedical Engineering Source Type: research

Model Order Selection Based on Information Theoretic Criteria: Design of the Penalty
Information theoretic criteria (ITC) have been widely adopted in engineering and statistics for selecting among an ordered set of candidate models the one that better fits the observed sample data. The selected model minimizes a penalized likelihood metric, where the penalty is determined by the criterion adopted. While rules for choosing a penalty that guarantees a consistent estimate of the model order are known, theoretical tools for its design with finite samples have never been provided in a general setting. In this paper, we study model order selection for finite samples under a design perspective, focusing on the ge...
Source: IEEE Transactions on Signal Processing - May 1, 2015 Category: Biomedical Engineering Source Type: research

Albumin Dialysis in Artificial Liver Support Systems: Open-Loop or Closed-Loop Dialysis Mode?
In artificial liver support systems, the open-loop albumin dialysis mode (OLM) is usually used to remove protein-bound toxins from the blood of patients with liver failure. However, there is still interest in the closed-loop albumin dialysis mode (CLM) because this mode may enable not only the regeneration and reuse of albumin but also the miniaturization of artificial liver systems. In this article, we compared the two modes under a fixed amount of albumin in dialysate experimentally and theoretically. The results show that according to the detoxification efficiency in the 3 hour dialysis for removing albumin-bound biliru...
Source: ASAIO Journal - May 1, 2015 Category: Medical Equipment Tags: Biomedical Engineering Source Type: research

Hemodynamic Monitoring of Large Animal Chronic Studies After Median Sternotomy: Experiences With Different Telemetric Physiological Devices
In conclusion, TPMS implantation was feasible via median sternotomy in lambs. Telemetric physiological monitoring systems significantly improve reliability of hemodynamic monitoring in chronic survival animal study. EG1 was less costly than PTD. (Source: ASAIO Journal)
Source: ASAIO Journal - May 1, 2015 Category: Medical Equipment Tags: Biomedical Engineering Source Type: research

Table of Contents
Presents the table of contents for this issue of the publication. (Source: IEE Transactions on Medical Imaging)
Source: IEE Transactions on Medical Imaging - May 1, 2015 Category: Biomedical Engineering Source Type: research

IEEE Transactions on Medical Imaging publication information
Provides a listing of the editors, board members, and current staff for this issue of the publication. (Source: IEE Transactions on Medical Imaging)
Source: IEE Transactions on Medical Imaging - May 1, 2015 Category: Biomedical Engineering Source Type: research

Spectral Laplace-Beltrami Wavelets With Applications in Medical Images
The spectral graph wavelet transform (SGWT) has recently been developed to compute wavelet transforms of functions defined on non-Euclidean spaces such as graphs. By capitalizing on the established framework of the SGWT, we adopt a fast and efficient computation of a discretized Laplace-Beltrami (LB) operator that allows its extension from arbitrary graphs to differentiable and closed 2-D manifolds (smooth surfaces embedded in the 3-D Euclidean space). This particular class of manifolds are widely used in bioimaging to characterize the morphology of cells, tissues, and organs. They are often discretized into triangular mes...
Source: IEE Transactions on Medical Imaging - May 1, 2015 Category: Biomedical Engineering Source Type: research

Transfer Learning Improves Supervised Image Segmentation Across Imaging Protocols
We present four transfer classifiers that can train a classification scheme with only a small amount of representative training data, in addition to a larger amount of other training data with slightly different characteristics. The performance of the four transfer classifiers was compared to that of standard supervised classification on two magnetic resonance imaging brain-segmentation tasks with multi-site data: white matter, gray matter, and cerebrospinal fluid segmentation; and white-matter-/MS-lesion segmentation. The experiments showed that when there is only a small amount of representative training data available, ...
Source: IEE Transactions on Medical Imaging - May 1, 2015 Category: Biomedical Engineering Source Type: research

A Hybrid LDA+gCCA Model for fMRI Data Classification and Visualization
Linear predictive models are applied to functional MRI (fMRI) data to estimate boundaries that predict experimental task states for scans. These boundaries are visualized as statistical parametric maps (SPMs) and range from low to high spatial reproducibility across subjects (e.g., Strother , 2004; LaConte , 2003). Such inter-subject pattern reproducibility is an essential characteristic of interpretable SPMs that generalize across subjects. Therefore, we introduce a flexible hybrid model that optimizes reproducibility by simultaneously enhancing the prediction power and reproducibility. This hybrid model is formed by a we...
Source: IEE Transactions on Medical Imaging - May 1, 2015 Category: Biomedical Engineering Source Type: research

Three Dimensional Data-Driven Multi Scale Atomic Representation of Optical Coherence Tomography
In this paper, we discuss about applications of different methods for decomposing a signal over elementary waveforms chosen in a family called a dictionary (atomic representations) in optical coherence tomography (OCT). If the representation is learned from the data, a nonparametric dictionary is defined with three fundamental properties of being data-driven, applicability on 3D, and working in multi-scale, which make it appropriate for processing of OCT images. We discuss about application of such representations including complex wavelet based K-SVD, and diffusion wavelets on OCT data. We introduce complex wavelet based ...
Source: IEE Transactions on Medical Imaging - May 1, 2015 Category: Biomedical Engineering Source Type: research

Graph-Based Airway Tree Reconstruction From Chest CT Scans: Evaluation of Different Features on Five Cohorts
We present a graph-based framework for airway tree reconstruction from computerized tomography (CT) scans and evaluate the performance of different feature categories and their combinations on five lung cohorts. The approach consists of two main processing steps. First, potential airway branch and connection candidates are identified and represented by a graph structure with weighted nodes and edges, respectively. Second, an optimization algorithm is utilized for generating an airway detection result by selecting a subset of airway branches and connections based on graph weights derived from image features. The performance...
Source: IEE Transactions on Medical Imaging - May 1, 2015 Category: Biomedical Engineering Source Type: research

Magnetic Particle Imaging With Tailored Iron Oxide Nanoparticle Tracers
Magnetic particle imaging (MPI) shows promise for medical imaging, particularly in angiography of patients with chronic kidney disease. As the first biomedical imaging technique that truly depends on nanoscale materials properties, MPI requires highly optimized magnetic nanoparticle tracers to generate quality images. Until now, researchers have relied on tracers optimized for MRI ${rm T}2^ {ast} $-weighted imaging that are sub-optimal for MPI. Here, we describe new tracers tailored to MPI's unique physics, synthesized using an organic-phase process and functionalized to ensure biocompatibility and adequate in vivo circula...
Source: IEE Transactions on Medical Imaging - May 1, 2015 Category: Biomedical Engineering Source Type: research

Three-Dimensional Nonrigid MR-TRUS Registration Using Dual Optimization
In this study, we proposed an efficient nonrigid magnetic resonance (MR) to transrectal ultrasound (TRUS) deformable registration method in order to improve the accuracy of targeting suspicious regions during a three dimensional (3-D) TRUS guided prostate biopsy. The proposed deformable registration approach employs the multi-channel modality independent neighborhood descriptor (MIND) as the local similarity feature across the two modalities of MR and TRUS, and a novel and efficient duality-based convex optimization-based algorithmic scheme was introduced to extract the deformations and align the two MIND descriptors. The ...
Source: IEE Transactions on Medical Imaging - May 1, 2015 Category: Biomedical Engineering Source Type: research

Learning Structured Models for Segmentation of 2-D and 3-D Imagery
Efficient and accurate segmentation of cellular structures in microscopic data is an essential task in medical imaging. Many state-of-the-art approaches to image segmentation use structured models whose parameters must be carefully chosen for optimal performance. A popular choice is to learn them using a large-margin framework and more specifically structured support vector machines (SSVM). Although SSVMs are appealing, they suffer from certain limitations. First, they are restricted in practice to linear kernels because the more powerful nonlinear kernels cause the learning to become prohibitively expensive. Second, they ...
Source: IEE Transactions on Medical Imaging - May 1, 2015 Category: Biomedical Engineering Source Type: research

Apparent Ultra-High $b$-Value Diffusion-Weighted Image Reconstruction via Hidden Conditional Random Fields
A promising, recently explored, alternative to ultra-high $b$-value diffusion weighted imaging (UHB-DWI) is apparent ultra-high $b$-value diffusion-weighted image reconstruction (AUHB-DWR), where a computational model is used to assist in the reconstruction of apparent DW images at ultra-high $b$ -values. Firstly, we present a novel approach to AUHB-DWR that aims to improve image quality. We formulate the reconstruction of an apparent DW image as a hidden conditional random field (HCRF) in which tissue model diffusion parameters act as hidden states in this random field. The second contribution of this paper is a new gener...
Source: IEE Transactions on Medical Imaging - May 1, 2015 Category: Biomedical Engineering Source Type: research

Domain Adaptation for Microscopy Imaging
Electron and light microscopy imaging can now deliver high-quality image stacks of neural structures. However, the amount of human annotation effort required to analyze them remains a major bottleneck. While machine learning algorithms can be used to help automate this process, they require training data, which is time-consuming to obtain manually, especially in image stacks. Furthermore, due to changing experimental conditions, successive stacks often exhibit differences that are severe enough to make it difficult to use a classifier trained for a specific one on another. This means that this tedious annotation process ha...
Source: IEE Transactions on Medical Imaging - May 1, 2015 Category: Biomedical Engineering Source Type: research

Optimized Detector Angular Configuration Increases the Sensitivity of X-ray Fluorescence Computed Tomography (XFCT)
In this work, we demonstrated that an optimized detector angular configuration based on the anisotropic energy distribution of background scattered X-rays improves X-ray fluorescence computed tomography (XFCT) detection sensitivity. We built an XFCT imaging system composed of a bench-top fluoroscopy X-ray source, a CdTe X-ray detector, and a phantom motion stage. We imaged a 6.4-cm-diameter phantom containing different concentrations of gold solution and investigated the effect of detector angular configuration on XFCT image quality. Based on our previous theoretical study, three detector angles were considered. The X-ray ...
Source: IEE Transactions on Medical Imaging - May 1, 2015 Category: Biomedical Engineering Source Type: research

Analysis of the Noise Correlation in MRI Coil Arrays Loaded With Metamaterial Magnetoinductive Lenses
A numerical method is shown for calculating the noise correlation coefficient in arrays of magnetic resonance imaging (MRI) coils loaded with capacitively-loaded ring metamaterial lenses, and in the presence of a conducting half-space resembling a sample. This numerical method is validated by comparison with experimental results obtained in two different experimental procedures for double check: noise resistance measurements with a network analyzer and noise correlation measurements in an MRI system. It is found that, for practical array configurations such as overlapping coils or capacitively-decoupled coils, the noise co...
Source: IEE Transactions on Medical Imaging - May 1, 2015 Category: Biomedical Engineering Source Type: research

Nonparametric Hemodynamic Deconvolution of fMRI Using Homomorphic Filtering
Functional magnetic resonance imaging (fMRI) is an indirect measure of neural activity which is modeled as a convolution of the latent neuronal response and the hemodynamic response function (HRF). Since the sources of HRF variability can be nonneural in nature, the measured fMRI signal does not faithfully represent underlying neural activity. Therefore, it is advantageous to deconvolve the HRF from the fMRI signal. However, since both latent neural activity and the voxel-specific HRF is unknown, the deconvolution must be blind. Existing blind deconvolution approaches employ highly parameterized models, and it is unclear w...
Source: IEE Transactions on Medical Imaging - May 1, 2015 Category: Biomedical Engineering Source Type: research

Detecting Statistically Significant Differences in Quantitative MRI Experiments, Applied to Diffusion Tensor Imaging
In this work we present a framework for reliably detecting significant differences in quantitative magnetic resonance imaging and evaluate it with diffusion tensor imaging (DTI) experiments. As part of this framework we propose a new spatially regularized maximum likelihood estimator that simultaneously estimates the quantitative parameters and the spatially-smoothly-varying noise level from the acquisitions. The noise level estimation method does not require repeated acquisitions. We show that the amount of regularization in this method can be set a priori to achieve a desired coefficient of variation of the estimated noi...
Source: IEE Transactions on Medical Imaging - May 1, 2015 Category: Biomedical Engineering Source Type: research

Simultaneous Multi-Scale Diffusion Estimation and Tractography Guided by Entropy Spectrum Pathways
We have developed a method for the simultaneous estimation of local diffusion and the global fiber tracts based upon the information entropy flow that computes the maximum entropy trajectories between locations and depends upon the global structure of the multi-dimensional and multi-modal diffusion field. Computation of the entropy spectrum pathways requires only solving a simple eigenvector problem for the probability distribution for which efficient numerical routines exist, and a straight forward integration of the probability conservation through ray tracing of the convective modes guided by a global structure of the e...
Source: IEE Transactions on Medical Imaging - May 1, 2015 Category: Biomedical Engineering Source Type: research

2015 IEEE Nuclear Science Symposium & Medical imaging Conference
Prospective authors are requested to submit new, unpublished manuscripts for inclusion in the upcoming event described in this call for papers. (Source: IEE Transactions on Medical Imaging)
Source: IEE Transactions on Medical Imaging - May 1, 2015 Category: Biomedical Engineering Source Type: research

Signal and informatin processing over networks
Prospective authors are requested to submit new, unpublished manuscripts for inclusion in the upcoming event described in this call for papers. (Source: IEE Transactions on Medical Imaging)
Source: IEE Transactions on Medical Imaging - May 1, 2015 Category: Biomedical Engineering Source Type: research

IEEE international symposium on biomedical imaging
Prospective authors are requested to submit new, unpublished manuscripts for inclusion in the upcoming event described in this call for papers. (Source: IEE Transactions on Medical Imaging)
Source: IEE Transactions on Medical Imaging - May 1, 2015 Category: Biomedical Engineering Source Type: research

IEEE Transactions on Medical Imaging information for authors
These instructions give guidelines for preparing papers for this publication. Presents information for authors publishing in this journal. (Source: IEE Transactions on Medical Imaging)
Source: IEE Transactions on Medical Imaging - May 1, 2015 Category: Biomedical Engineering Source Type: research

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This page or pages intentionally left blank. (Source: IEE Transactions on Medical Imaging)
Source: IEE Transactions on Medical Imaging - May 1, 2015 Category: Biomedical Engineering Source Type: research

Pupillometric sleepiness measurements PST with concurrent video optic sensor of pupillary size
Publication date: Available online 22 April 2015 Source:Biocybernetics and Biomedical Engineering Author(s): Krzysztof Różanowski , Tadeusz Sondej , Jarosław Lewandowski The article describes the design solutions of a mobile headset device used for the assessment of involuntary and oscillatory movements of the pupils. The pupillographic sleepiness test (PST) is used to assess the human psychophysiological state influenced by the level of drowsiness or alertness by observing the so-called fatigue wave. Since the overall size of the pupil is controlled predominantly by sympathetic inhibition of the parasympathetic Eding...
Source: Biocybernetics and Biomedical Engineering - May 1, 2015 Category: Biomedical Engineering Source Type: research

Whole slurry saccharification and fermentation of maleic acid-pretreated rice straw for ethanol production.
Abstract We evaluated the feasibility of whole slurry (pretreated lignocellulose) saccharification and fermentation for producing ethanol from maleic acid-pretreated rice straw. The optimized conditions for pretreatment were to treat rice straw at a high temperature (190 °C) with 1 % (w/v) maleic acid for a short duration (3 min ramping to 190 °C and 3 min holding at 190 °C). Enzymatic digestibility (based on theoretical glucose yield) of cellulose in the pretreated rice straw was 91.5 %. Whole slurry saccharification and fermentation of pretreated rice straw resulted in 83.2 % final yield of ethanol bas...
Source: Bioprocess and Biosystems Engineering - May 1, 2015 Category: Biomedical Engineering Authors: Jung YH, Park HM, Kim KH Tags: Bioprocess Biosyst Eng Source Type: research

Apparent Ultra-High -Value Diffusion-Weighted Image Reconstruction via Hidden Conditional Random Fields
A promising, recently explored, alternative to ultra-high b-value diffusion weighted imaging (UHB-DWI) is apparent ultra-high b-value diffusion-weighted image reconstruction (AUHB-DWR), where a computational model is used to assist in the reconstruction of apparent DW images at ultra-high b-values. Firstly, we present a novel approach to AUHB-DWR that aims to improve image quality. We formulate the reconstruction of an apparent DW image as a hidden conditional random field (HCRF) in which tissue model diffusion parameters act as hidden states in this random field. The second contribution of this paper is a new generation o...
Source: IEE Transactions on Medical Imaging - May 1, 2015 Category: Biomedical Engineering Source Type: research

Review and the state of the art: Sol–gel and melt quenched bioactive glasses for tissue engineering
This article is an attempt to provide state of the art of the sol–gel and melt quenched bioactive bioglasses for tissue regeneration. Fabrication routes for bioglasses suitable for bone tissue engineering are highlighted and the effect of these fabrication techniques on the porosity, pore‐volume, mechanical properties, cytocompatibilty and especially apatite layer formation on the surface of bioglasses is analyzed in detail. Drug delivery capability of bioglasses is addressed shortly along with the bioactivity of mesoporous glasses. © 2015 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2015. (Source...
Source: Journal of Biomedical Materials Research Part B: Applied Biomaterials - May 1, 2015 Category: Materials Science Authors: Gurbinder Kaur, Gary Pickrell, Nammalwar Sriranganathan, Vishal Kumar, Daniel Homa Tags: Review Article Source Type: research

Reference point detection for camera-based fingerprint image based on wavelet transformation
Conclusion: The proposed method yields promising results in a collected-image database. Moreover, the proposed method outperformed compare to existing method. (Source: BioMedical Engineering OnLine)
Source: BioMedical Engineering OnLine - April 30, 2015 Category: Biomedical Engineering Authors: Mohammed Khalil Source Type: research

Corrigendum to “Biomechanical analysis of different types of pedicle screw augmentation: a cadaveric and synthetic bone sample study of instrumented vertebral specimens” [Med. Eng. Phys. 35/10 (2013) 1506–1522]
The authors wish to report the following errors in the aforementioned article: (Source: Medical Engineering and Physics)
Source: Medical Engineering and Physics - April 30, 2015 Category: Biomedical Engineering Authors: Kuo-Hua Chao, Yu-Shu Lai, Wen-Chuan Chen, Chia-Ming Chang, Colin J. McClean, Chang-Yuan Fan, Chia-Hao Chang, Leou-Chyr Lin, Cheng-Kung Cheng Tags: Corrigendum Source Type: research

Use of wearable technology for performance assessment: A validation study
Osteoarthritis (OA) represents one of the most common forms of musculoskeletal disorders affecting predominately load bearing joints [1]. It ranks as the second leading cause of disability and the fastest growing major health condition [2]. Estimates show that more than 250 million people worldwide are affected by OA of the knee [3] and this number is expected to increase in relation to expanding ageing population, increased obesity and lack of physical activity [2,4]. (Source: Medical Engineering and Physics)
Source: Medical Engineering and Physics - April 30, 2015 Category: Biomedical Engineering Authors: Enrica Papi, Denise Osei-Kuffour, Yen-Ming A Chen, Alison H McGregor Tags: Technical note Source Type: research

Multi-selective catheter for MR-guided endovascular interventions
Selective catheters have predefined distal shapes and need to be exchanged to change tip geometry to facilitate selective catheterization of vascular side branches. These repeated insertions increase the risk of endovascular injury and radiation dose in conventional catheterization laboratories.The aim of this study is to develop a multi-selective catheter that can replace three conventional selective catheters that are commonly used sequentially in a single procedure. By integrating the different shapes in one instrument, it is possible to avoid the required time-consuming exchange. (Source: Medical Engineering and Physics)
Source: Medical Engineering and Physics - April 30, 2015 Category: Biomedical Engineering Authors: Helene C.M. Clogenson, Joris Y. van Lith, Jenny Dankelman, Andreas Melzer, John J. van den Dobbelsteen Source Type: research

Friction characteristics of trocars in laparoscopic surgery
This article investigates the friction characteristics of the instrument–trocar interface in laparoscopic surgery for varying linear instrument velocities, trocar seal design and material, and trocar tilt. Furthermore, the effect of applying lubrication at the instrument–trocar seal interface on friction was studied. A friction testing apparatus was designed and built to characterise the resistance force at the instrument–trocar interface as a function of the instrument’s linear movement in the 12-mm trocar (at constant velocity) for different design, seal material, and angle of tilt. The resistance...
Source: Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine - April 30, 2015 Category: Biomedical Engineering Authors: Alazmani, A., Roshan, R., Jayne, D. G., Neville, A., Culmer, P. Tags: Original Articles Source Type: research

Subject-specific finite element model with an optical tracking system in total hip replacement surgery
This study combines subject-specific finite element analysis modeling with an optical tracking system to characterize the resultant strain in the bone and results of impaction during total hip replacement surgery. The use of ABG II femoral stem (Stryker Orthopaedics, Mahwah, NJ, USA) in the model yielded the following results. Hammer velocity was measured experimentally using a three-dimensional optical tracking system and these data were input into the finite element analysis model so that intra-operative loading scenario could be simulated. A quasi-static explicit simulation and a dynamic loading step using two implant&n...
Source: Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine - April 30, 2015 Category: Biomedical Engineering Authors: Miles, B., Kolos, E., Walter, W. L., Appleyard, R., Li, Q., Chen, Y., Ruys, A. J. Tags: Original Articles Source Type: research

Physiological outflow boundary conditions methodology for small arteries with multiple outlets: A patient-specific hepatic artery haemodynamics case study
This study derives physiological outflow boundary conditions for cases in which the physiological values at those outlets are not known (neither in vivo measurements nor literature-based values are available) and in which the tree exhibits symmetry to some extent. The inputs of the methodology are the three-dimensional domain and the flow rate waveform and the systolic and diastolic pressures at the inlet. The derived physiological outflow boundary conditions, which are a physiological pressure waveform for each outlet, are based on the results of a zero-dimensional model simulation. The methodology assumes symmetrical bra...
Source: Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine - April 30, 2015 Category: Biomedical Engineering Authors: Aramburu, J., Anton, R., Bernal, N., Rivas, A., Ramos, J. C., Sangro, B., Bilbao, J. I. Tags: Original Articles Source Type: research

Effect of SiC interlayer between Ti6Al4V alloy and hydroxyapatite films
Bioactive coatings are frequently used to improve the osseointegration of the metallic implants used in dentistry or orthopaedics. Among different types of bioactive coatings, hydroxyapatite (Ca10(PO4)6(OH)2) is one of the most extensively used due to its chemical similarities to the components of bones and teeth. In this article, production and characterization of hydroxyapatite films deposited on Ti6Al4V alloy prepared by magnetron sputtering were reported. Besides, SiC was deposited on substrate surface to study the interlayer effect. Obtained coatings were annealed at 600 °C for 30 and 120 min in a mixed atmosphere...
Source: Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine - April 30, 2015 Category: Biomedical Engineering Authors: Azem, F. A., Birlik, I., Braic, V., Toparli, M., Celik, E., Parau, A., Kiss, A., Titorencu, I., Vladescu, A. Tags: Original Articles Source Type: research

Automated hand thermal image segmentation and feature extraction in the evaluation of rheumatoid arthritis
The aim of the study was (1) to perform an automated segmentation of hot spot regions of the hand from thermograph using the k-means algorithm and (2) to test the potential of features extracted from the hand thermograph and its measured skin temperature indices in the evaluation of rheumatoid arthritis. Thermal image analysis based on skin temperature measurement, heat distribution index and thermographic index was analyzed in rheumatoid arthritis patients and controls. The k-means algorithm was used for image segmentation, and features were extracted from the segmented output image using the gray-level co-occurrence matr...
Source: Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine - April 30, 2015 Category: Biomedical Engineering Authors: Snekhalatha, U., Anburajan, M., Sowmiya, V., Venkatraman, B., Menaka, M. Tags: Original Articles Source Type: research

Immobilization of β-galactosidase from Lactobacillus plantarum HF571129 on ZnO nanoparticles: characterization and lactose hydrolysis.
Abstract β-Galactosidase from Lactobacillus plantarum HF571129 was immobilized on zinc oxide nanoparticles (ZnO NPs) using adsorption and cross-linking technique. Immobilized β-galactosidase showed broad-spectrum pH optima at pH 5-7.5 and temperature 50-60 °C. Fourier transform infrared spectroscopy (FTIR) and field emission scanning electron microscopy (FESEM) showed that β-galactosidase successfully immobilized onto supports. Due to the limited diffusion of high molecular weight substrate, K m of immobilized enzyme slightly increased from 6.64 to 10.22 mM, while V max increased from 147.5 to 192.4 µmol m...
Source: Bioprocess and Biosystems Engineering - April 30, 2015 Category: Biomedical Engineering Authors: Selvarajan E, Mohanasrinivasan V, Subathra Devi C, George Priya Doss C Tags: Bioprocess Biosyst Eng Source Type: research

Saccharification of sunflower stalks using lignocellulases from a fungal consortium comprising Pholiota adiposa and Armillaria gemina.
Abstract Lignocellulases from Armillaria gemina and Pholiota adiposa are efficient in hydrolyzing aspen and poplar biomass, respectively. In the present study, lignocellulosic enzymes obtained from a fungal consortium comprising P. adiposa and A. gemina were used for the saccharification of sunflower stalks. Sunflower stalks were thermochemically pretreated using 2 % NaOH at 50 °C for 24 h. The saccharification process parameters including substrate concentration, enzyme loading, pH, and temperature were optimized using response surface methodology to improve the saccharification yield. The highest enzymatic hy...
Source: Bioprocess and Biosystems Engineering - April 30, 2015 Category: Biomedical Engineering Authors: Ramachandran P, Kim TS, Dhiman SS, Li J, Park JH, Choi JH, Kim JY, Kim D, Lee JK Tags: Bioprocess Biosyst Eng Source Type: research

Ethics policies and procedures in imaging and interventional radiology
(Source: Australasian Physical and Engineering Sciences in Medicine)
Source: Australasian Physical and Engineering Sciences in Medicine - April 30, 2015 Category: Biomedical Engineering Source Type: research

Effect of Intensified Decellularization of Equine Carotid Arteries on Scaffold Biomechanics and Cytotoxicity.
Abstract Decellularized equine carotid arteries (dEAC) are suggested to represent an alternative for alloplastic vascular grafts in haemodialysis patients to achieve vascular access. Recently it was shown that intensified detergent treatment completely removed cellular components from dEAC and thereby significantly reduced matrix immunogenicity. However, detergents may also affect matrix composition and stability and render scaffolds cytotoxic. Therefore, intensively decellularized carotids (int-dEAC) were now evaluated for their biomechanical characteristics (suture retention strength, burst pressure and circumfer...
Source: Annals of Biomedical Engineering - April 29, 2015 Category: Biomedical Engineering Authors: Böer U, Hurtado-Aguilar LG, Klingenberg M, Lau S, Jockenhoevel S, Haverich A, Wilhelmi M Tags: Ann Biomed Eng Source Type: research