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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 20.

Society Awards 2014
(Source: Journal of Biomechanical Engineering)
Source: Journal of Biomechanical Engineering - January 24, 2015 Category: Biomedical Engineering Source Type: research

Acknowledgments for the 3rd Annual Special Issue of The Journal of Biomechanical Engineering
In the last year, Journal of Biomechanical Engineering (JBME) has continued to thrive, with increasing submissions and decreasing review times. The number of manuscripts submitted each year remains on the rise and our acceptance rate continues to become more selective, while our review times continue to improve. The continued selectivity and improved review speed is a credit to all of our Associate Editors and reviewers. In the last year, we have added three new Associate Editors which has helped to keep up with the increased submissions and reduced review time. We are grateful to all of them for their service and dedicati...
Source: Journal of Biomechanical Engineering - January 24, 2015 Category: Biomedical Engineering Source Type: research

Is aortic wall shear stress affected by aging? An image-based numerical study with two age groups
Blood vessels are continuously affected by the pulsating blood flow and are normally subjected to two types of forces: the blood pressure (BP) and the wall shear stress (WSS). The pressure is directed normal to the wall and the wall shear stress tangential to the wall, and in healthy humans the blood pressure is about 1000 times larger than the shear forces, but both have been found to affect the vessel wall in different ways. The stress in the wall is the result of the residual stresses (present even in a non-pressurized vessel) and the blood pressure, and the stress level determines the amount of stretching in radial, t...
Source: Medical Engineering and Physics - January 24, 2015 Category: Biomedical Engineering Authors: Jonas Lantz, Johan Renner, Toste Länne, Matts Karlsson Source Type: research

Colourimetric image analysis as a diagnostic tool in female genital schistosomiasis
Female genital schistosomiasis (FGS) is a poverty-related disease caused by the water-transmitted parasite Schistosoma haematobium. The disease may create lesions and inflammation in the genital tract [1]. It is highly prevalent in certain rural areas of Africa, which have limited access to health care and diagnostics. The disease may cause vaginal bleeding, discomfort, dyspareunia, infertility and it might increase the risk of acquiring HIV [1–3]. (Source: Medical Engineering and Physics)
Source: Medical Engineering and Physics - January 24, 2015 Category: Biomedical Engineering Authors: Sigve Dhondup Holmen, Eyrun Floerecke Kjetland, Myra Taylor, Elisabeth Kleppa, Kristine Lillebø, Svein Gunnar Gundersen, Mathias Onsrud, Fritz Albregtsen Tags: Technical note Source Type: research

Vascularization in Bone Tissue Engineering Constructs.
Abstract Vascularization of large bone grafts is one of the main challenges of bone tissue engineering (BTE), and has held back the clinical translation of engineered bone constructs for two decades so far. The ultimate goal of vascularized BTE constructs is to provide a bone environment rich in functional vascular networks to achieve efficient osseointegration and accelerate restoration of function after implantation. To attain both structural and vascular integration of the grafts, a large number of biomaterials, cells, and biological cues have been evaluated. This review will present biological considerations fo...
Source: Annals of Biomedical Engineering - January 24, 2015 Category: Biomedical Engineering Authors: Mercado-Pagán ÁE, Stahl AM, Shanjani Y, Yang Y Tags: Ann Biomed Eng Source Type: research

A State-Space Approach to Dynamic Nonnegative Matrix Factorization
Nonnegative matrix factorization (NMF) has been actively investigated and used in a wide range of problems in the past decade. A significant amount of attention has been given to develop NMF algorithms that are suitable to model time series with strong temporal dependencies. In this paper, we propose a novel state-space approach to perform dynamic NMF (D-NMF). In the proposed probabilistic framework, the NMF coefficients act as the state variables and their dynamics are modeled using a multi-lag nonnegative vector autoregressive (N-VAR) model within the process equation. We use expectation maximization and propose a maximu...
Source: IEEE Transactions on Signal Processing - January 23, 2015 Category: Biomedical Engineering Source Type: research

Partial-Aliasing Correlation Filters
Correlation filters (CFs) are useful tools for detecting and locating signals or objects within a larger signal or scene of interest. Typically, these filters are designed during the training stage without worrying about how the cross-correlation between a test signal and the designed CF template will be carried out during the testing or use stage. Because of its computational benefits, the Fast Fourier Transform (FFT) algorithm is usually used for performing cross-correlations, leading to circular correlations and aliasing in the resulting correlation outputs. The aliasing effects can be suppressed by zero-padding, but at...
Source: IEEE Transactions on Signal Processing - January 23, 2015 Category: Biomedical Engineering Source Type: research

Bayesian Hypothesis Test Using Nonparametric Belief Propagation for Noisy Sparse Recovery
This paper proposes a low-computational Bayesian algorithm for noisy sparse recovery (NSR), called BHT-BP. In this framework, we consider an LDPC-like measurement matrices which has a tree-structured property, and additive white Gaussian noise. BHT-BP has a joint detection-and-estimation structure consisting of a sparse support detector and a nonzero estimator. The support detector is designed under the criterion of the minimum detection error probability using a nonparametric belief propagation (nBP) and composite binary hypothesis tests. The nonzeros are estimated in the sense of linear MMSE, where the support detection ...
Source: IEEE Transactions on Signal Processing - January 23, 2015 Category: Biomedical Engineering Source Type: research

Robust Optimization of Order Execution
Order execution for algorithmic trading has been studied in the literature to determine the optimal strategy by minimizing a trade-off between expected execution cost and risk. Usually, the variance of the execution cost is taken as a proxy of risk due to mathematical tractability. However, the variance has been recognized not to be practical since it is a symmetric measure of risk and, hence, penalizes the low-cost events. In this paper, we propose the use of the conditional value-at-risk (CVaR) of the execution cost as risk measure, which allows to take into consideration only the unfavorable part of the return distribut...
Source: IEEE Transactions on Signal Processing - January 23, 2015 Category: Biomedical Engineering Source Type: research

Lower-Order $H_{infty} $ Filter Design for Bilinear Systems With Bounded Inputs
We propose an optimization-based method for designing a lower order Luenberger-type state estimator, while providing $L_{2}$-gain guarantees on the error dynamics when the estimator is used with the higher order system. Suitable filter parameters can be computed by modelling the bilinear system as a linear differential inclusion and solving a set of bilinear matrix inequality constraints. Since these constraints are nonconvex, in general, we also show that one can solve a suitably defined semi-definite program to compute a bound on the level of suboptimality. The design method also allows one to explicitly take account of ...
Source: IEEE Transactions on Signal Processing - January 23, 2015 Category: Biomedical Engineering Source Type: research

New Robust Estimators of Correlation and Weighted Basis Pursuit
The autocorrelation function is a commonly used tool in statistical time series analysis. In this paper we examine the robustness of two estimators of correlation based on memoryless nonlinear functions of the observations, the Median-of-Ratios Estimator (MRE) and the Phase-Phase Correlator (PPC), which are applicable to complex-valued Gaussian random processes. We show that they are robust to impulsive noise from a bias perspective at the expense of statistical efficiency at the Gaussian distribution. Additionally, we develop iterative versions of these estimators named the IMRE and IPPC, realizing an improved bias perfor...
Source: IEEE Transactions on Signal Processing - January 23, 2015 Category: Biomedical Engineering Source Type: research

Compressive Parameter Estimation for Sparse Translation-Invariant Signals Using Polar Interpolation
We propose new compressive parameter estimation algorithms that make use of polar interpolation to improve the estimator precision. Our work extends previous approaches involving polar interpolation for compressive parameter estimation in two aspects: (i) we extend the formulation from real non-negative amplitude parameters to arbitrary complex ones, and (ii) we allow for mismatch between the manifold described by the parameters and its polar approximation. To quantify the improvements afforded by the proposed extensions, we evaluate six algorithms for estimation of parameters in sparse translation-invariant signals, exemp...
Source: IEEE Transactions on Signal Processing - January 23, 2015 Category: Biomedical Engineering Source Type: research

Analysis and Comparison of Biased Affine Estimators
Affine biased estimation is particularly useful when there is some a-priori knowledge on the parameters that can be exploited in adverse situations (when the number of samples is low, or the noise is high). Three different affine estimation strategies are discussed, namely the Deepest Minimum Criterion (DMC), the Min-Max (MM), and the Linear Matrix Inequality (LMI) strategies, and closed form expressions are obtained for all of them, for the case when the a priori knowledge is given in the form of ellipsoidal constraints on the parameter space, and when the covariance matrix of the unbiased estimator is constant. A relatio...
Source: IEEE Transactions on Signal Processing - January 23, 2015 Category: Biomedical Engineering Source Type: research

Asynchronous Adaptation and Learning Over Networks—Part II: Performance Analysis
In Part I of this paper, also in this issue, we introduced a fairly general model for asynchronous events over adaptive networks including random topologies, random link failures, random data arrival times, and agents turning on and off randomly. We performed a stability analysis and established the notable fact that the network is still able to converge in the mean-square-error sense to the desired solution. Once stable behavior is guaranteed, it becomes important to evaluate how fast the iterates converge and how close they get to the optimal solution. This is a demanding task due to the various asynchronous events and d...
Source: IEEE Transactions on Signal Processing - January 23, 2015 Category: Biomedical Engineering Source Type: research

Asynchronous Adaptation and Learning Over Networks—Part III: Comparison Analysis
In Part II of this paper, also in this issue, we carried out a detailed mean-square-error analysis of the performance of asynchronous adaptation and learning over networks under a fairly general model for asynchronous events including random topologies, random link failures, random data arrival times, and agents turning on and off randomly. In this Part III, we compare the performance of synchronous and asynchronous networks. We also compare the performance of decentralized adaptation against centralized stochastic-gradient (batch) solutions. Two interesting conclusions stand out. First, the results establish that the perf...
Source: IEEE Transactions on Signal Processing - January 23, 2015 Category: Biomedical Engineering Source Type: research

Asynchronous Adaptation and Learning Over Networks—Part I: Modeling and Stability Analysis
In this work and the supporting Parts II and III of this paper, also in the current issue, we provide a rather detailed analysis of the stability and performance of asynchronous strategies for solving distributed optimization and adaptation problems over networks. We examine asynchronous networks that are subject to fairly general sources of uncertainties, such as changing topologies, random link failures, random data arrival times, and agents turning on and off randomly. Under this model, agents in the network may stop updating their solutions or may stop sending or receiving information in a random manner and without coo...
Source: IEEE Transactions on Signal Processing - January 23, 2015 Category: Biomedical Engineering Source Type: research

Table of Contents
(Source: IEEE Transactions on Biomedical Circuits and Systems)
Source: IEEE Transactions on Biomedical Circuits and Systems - January 23, 2015 Category: Biomedical Engineering Source Type: research

Congrès AACC 2014
Publication date: Available online 22 January 2015 Source:IRBM News Author(s): S. Vesseron , A. Hyvert , J.-M. Margas , A. Massei (Source: IRBM News)
Source: IRBM News - January 23, 2015 Category: Biomedical Engineering Source Type: research

Maîtrise des risques fournisseurs et sécurité juridique : les précautions à prendre lors de l’analyse des candidatures
Publication date: Available online 20 January 2015 Source:IRBM News Author(s): P.-Y. Siramy , Y. Daumin (Source: IRBM News)
Source: IRBM News - January 23, 2015 Category: Biomedical Engineering Source Type: research

Carotene-degrading activities from Bjerkandera adusta possess an application in detergent industries.
Abstract Four extracellular enzymes, a versatile peroxidase, a manganese peroxidase, a dye-decolorizing peroxidase and a lignin peroxidase were discovered in liquid cultures of the basidiomycete Bjerkandera adusta. All of them cleaved β-carotene effectively. Expression was enhanced in the presence of β-carotene or Coomassie Brilliant Blue and peaked after 7-9 days. The monomeric proteins were purified by ion exchange and size exclusion chromatography and exhibited molecular masses of 41, 43, 51 and 43 kDa, respectively. The coding sequences showed homologies from 61 to 89 % to peroxidases from other basidiomyc...
Source: Bioprocess and Biosystems Engineering - January 23, 2015 Category: Biomedical Engineering Authors: Linke D, Leonhardt R, Eisele N, Petersen LM, Riemer S, Nimtz M, Berger RG Tags: Bioprocess Biosyst Eng Source Type: research

Bioflavour production from tomato and pepper pomaces by Kluyveromyces marxianus and Debaryomyces hansenii.
Abstract Bioflavours are called natural flavour and/or fragrance compounds which are produced using metabolic pathway of the microorganism and/or plant cells or their enzyme systems with bioengineering approaches. The aim of this study was to investigate bioflavour production from tomato and red pepper pomaces by Kluyveromyces marxianus and Debaryomyces hansenii. Obtained specific growth rates of K. marxianus and D. hansenii in tomato pomace were 0.081/h and 0.177/h, respectively. The bioflavour profile differed between the yeasts. Both yeasts can produce esters and alcohols such as phenyl ethyl alcohol, isoamyl al...
Source: Bioprocess and Biosystems Engineering - January 23, 2015 Category: Biomedical Engineering Authors: Güneşer O, Demirkol A, Karagül Yüceer Y, Özmen Toğay S, İşleten Hoşoğlu M, Elibol M Tags: Bioprocess Biosyst Eng Source Type: research

Differential Effects of Tumor Secreted Factors on Mechanosensitivity, Capillary Branching, and Drug Responsiveness in PEG Hydrogels.
Abstract Solid cancers induce the formation of new blood vessels to promote growth and metastasis. Unlike the normal vascular networks, the tumor induced vasculatures exhibit abnormal shape and function. Past efforts have been focused on characterizing the altered growth factor signaling pathway in tumor capillary endothelial cells; however, the mechanical microenvironment of tumor also plays a significant role in regulating the formation of vascular patterns. Here, we used synthetic hydrogel based cell culture platforms to probe how activation of human umbilical endothelial cells (HUVECs) by tumor secreted factors...
Source: Annals of Biomedical Engineering - January 23, 2015 Category: Biomedical Engineering Authors: Wu Y, Guo B, Ghosh G Tags: Ann Biomed Eng Source Type: research

The Application of NCaRBS to the Trendelenburg Test and Total Hip Arthroplasty Outcome.
Abstract This paper compares the frontal plane hip function of subject's known to have had hip arthroplasty via either the lateral (LA) or posterior (PA) surgical approaches and a group of subjects associated with no pathology (NP). This is investigated through the Trendelenburg test using 3D motion analysis and classification. Here, a recent development on the Classification and Ranking Belief Simplex (CaRBS) technique, able to undertake n-state classification, so termed NCaRBS is employed. The relationship between post-operative hip function measured during a Trendelenburg Test using three patient characteristics...
Source: Annals of Biomedical Engineering - January 23, 2015 Category: Biomedical Engineering Authors: Whatling GM, Holt CA, Beynon MJ Tags: Ann Biomed Eng Source Type: research

An advanced compliance monitor for patients undergoing brace treatment for idiopathic scoliosis
Adolescent idiopathic scoliosis is a spinal deformity affecting 2–3% of adolescents. Brace treatment, the most common non-surgical treatment, uses a hard plastic orthotic shell to prevent progression of the deformity. Previous studies have found association between treatment outcome and patients’ compliance with the prescribed brace-wear regimen. However, the exact relationship between compliance and treatment outcome has yet to be elucidated. Current compliance monitoring techniques may not be providing enough information about patients’ brace-wear habits. (Source: Medical Engineering and Physics)
Source: Medical Engineering and Physics - January 22, 2015 Category: Biomedical Engineering Authors: Eric Chalmers, Edmond Lou, Doug Hill, H. Vicky Zhao Source Type: research

Waterjet cutting of periprosthetic interface tissue in loosened hip prostheses: An feasibility study
The first results using waterjet cutting in the medical field were reported in 1982 for liver resection [1]. Since then, waterjet cutting has become an established technique in different surgical fields [2]. The technique is used clinically for cutting soft tissues like liver tissue [3–6] and experimentally for dissecting spleen tissue [7,8], kidney tissue [9–12] and brain tissue [2,13,14]. Waterjets have also been investigated for cutting hard materials such as bone and bone cement [15–18]. (Source: Medical Engineering and Physics)
Source: Medical Engineering and Physics - January 22, 2015 Category: Biomedical Engineering Authors: Gert Kraaij, Gabrielle J.M. Tuijthof, Jenny Dankelman, Rob G.H.H. Nelissen, Edward R. Valstar Tags: Technical Note Source Type: research

Principal component analysis of atrial fibrillation: Inclusion of posterior ECG leads does not improve correlation with left atrial activity
It is widely accepted that the atrial waveform seen on the surface ECG during AF reflects intracardiac electrical activity [1,2]. The majority of research studies investigating surface ECG analysis in AF employ QRST subtraction as the method of extracting the AF waveform from the surface ECG. The two principal methods of QRST subtraction are average beat subtraction (ABS) and spatiotemporal QRST cancellation. ABS was initially developed to help identify P waves in ventricular tachycardia [3] and involves creation of an average QRST complex from a single ECG lead, which is then subtracted to leave the residual atrial signal...
Source: Medical Engineering and Physics - January 22, 2015 Category: Biomedical Engineering Authors: Daniel Raine, Philip Langley, Ewen Shepherd, Stephen Lord, Stephen Murray, Alan Murray, John P. Bourke Tags: Technical Note Source Type: research

A robust real-time gait event detection using wireless gyroscope and its application on normal and altered gaits
Gait events detection allows clinicians and biomechanics researchers to determine timing of gait events, to estimate duration of stance phase and swing phase and to segment gait data. It also aids biomedical engineers to improve the design of orthoses and FES (functional electrical stimulation) systems. In recent years, researchers have resorted to using gyroscopes to determine heel-strike (HS) and toe-off (TO) events in gait cycles. However, these methods are subjected to significant delays when implemented in real-time gait monitoring devices, orthoses, and FES systems. (Source: Medical Engineering and Physics)
Source: Medical Engineering and Physics - January 22, 2015 Category: Biomedical Engineering Authors: Darwin Gouwanda, Alpha Agape Gopalai Tags: Technical Note Source Type: research

Measurement of Head Impact Due to Standing Fall in Adults Using Anthropomorphic Test Dummies.
Abstract The kinematics and kinetics of head impact due to a standing fall onto a hard surface are summarized. Head injury due to impact from falls represents a significant problem, especially for older individuals. When the head is left unprotected during a fall, the impact severity can be high enough to cause significant injury or even death. To ascertain the range of head impact parameters, the dynamic response was captured for the pedestrian version of the 5th percentile female and 50th percentile male Hybrid III anthropomorphic test dummies as they were dropped from a standing position with different initial p...
Source: Annals of Biomedical Engineering - January 22, 2015 Category: Biomedical Engineering Authors: Hajiaghamemar M, Seidi M, Ferguson JR, Caccese V Tags: Ann Biomed Eng Source Type: research

Data dependent random forest applied to screening for laryngeal disorders through analysis of sustained phonation: Acoustic versus contact microphone
Automated analysis of voice signals is used increasingly in screening for laryngeal disorders [1–6]. Several parameters computed from voice signals are a convenient way of documentation and quantification of dysphonia changes and outcomes of therapeutic and surgical treatment of laryngeal disorders [4,7–10]. Although voice recordings have been carried out for many years in clinical practice, the debate on microphone selection is still going on [11–13]. (Source: Medical Engineering and Physics)
Source: Medical Engineering and Physics - January 21, 2015 Category: Biomedical Engineering Authors: A. Verikas, A. Gelzinis, E. Vaiciukynas, M. Bacauskiene, J. Minelga, M. Hållander, V. Uloza, E. Padervinskis Source Type: research

Development and validation of an accelerometer-based method for quantifying gait events
An original signal processing algorithm is presented to automatically extract, on a stride-by-stride basis, four consecutive fundamental events of walking, heel strike (HS), toe strike (TS), heel-off (HO), and toe-off (TO), from wireless accelerometers applied to the right and left foot. First, the signals recorded from heel and toe three-axis accelerometers are segmented providing heel and toe flat phases. Then, the four gait events are defined from these flat phases. The accelerometer-based event identification was validated in seven healthy volunteers and a total of 247 trials against reference data provided by a force ...
Source: Medical Engineering and Physics - January 21, 2015 Category: Biomedical Engineering Authors: Mohamed Boutaayamou, Cédric Schwartz, Julien Stamatakis, Vincent Denoël, Didier Maquet, Bénédicte Forthomme, Jean-Louis Croisier, Benoît Macq, Jacques G. Verly, Gaëtan Garraux, Olivier Brüls Tags: Technical Note Source Type: research

Investigation of Static and Dynamic Pull-in Instability in a FGP Micro-Beam
Abstract In this paper, static and dynamic behavior of a fully clamped functionally graded piezoelectric micro-beam, subjected to simultaneous electrostatic and piezoelectric actuations is investigated. The micro-beam is composed of silicon and PZ4 as a piezoelectric material. Applying DC piezoelectric voltage results in the generation of an axial force and as a result the equivalent bending stiffness of the micro-beam changes. The tunability of the bending stiffness due to piezoelectric actuation is used to stabilize the pull-in instability. The nonlinear governing equation of the motion is derived using Hamilto...
Source: Sensing and Imaging - January 21, 2015 Category: Biomedical Engineering Source Type: research

Acidic pH shock induced overproduction of ε-poly-L-lysine in fed-batch fermentation by Streptomyces sp. M-Z18 from agro-industrial by-products.
In this study, the effect of acidic pH shock on enhancing ε-PL production by Streptomyces sp. M-Z18 was investigated in a 5-L fermenter. Based on the evaluation of acidic pH shock on mycelia metabolic activity and shock parameters optimization, an integrated pH-shock strategy was developed as follows: pre-acid-shock adaption at pH 5.0 to alleviate the damage caused by the followed pH shock, and then acidic pH shock at 3.0 for 12 h (including pH decline from 4.0 to 3.0) to positively regulate mycelia metabolic activity, finally restoring pH to 4.0 to provide optimal condition for ε-PL production. After 192 h of fed-batc...
Source: Bioprocess and Biosystems Engineering - January 21, 2015 Category: Biomedical Engineering Authors: Ren XD, Chen XS, Zeng X, Wang L, Tang L, Mao ZG Tags: Bioprocess Biosyst Eng Source Type: research

Development of a more efficient process for production of fuel ethanol from bamboo.
Abstract A process for production of fuel ethanol from bamboo treated with concentrated sulfuric acid has been previously proposed. To improve efficiency of the process, we tested saccharification with 70 weight% (wt%) sulfuric acid, acid-sugar separation by ion exclusion, addition of nutrients to the ethanol fermentation, and bioconversion of xylose to xylitol. A high efficiency of both sugar recovery (82.5 %) and acid recovery (97.5 %) was achieved in the saccharification process and in the continuous acid-sugar separation using a modified anion exchange resin, respectively. Reduction of the amount of mineral ...
Source: Bioprocess and Biosystems Engineering - January 21, 2015 Category: Biomedical Engineering Authors: Sun ZY, Wang T, Tan L, Tang YQ, Kida K Tags: Bioprocess Biosyst Eng Source Type: research

MouthLab: A Tricorder Concept Optimized for Rapid Medical Assessment.
Abstract The goal of rapid medical assessment (RMA) is to estimate the general health of a patient during an emergency room or a doctor's office visit, or even while the patient is at home. Currently the devices used during RMA are typically "all-in-one" vital signs monitors. They require time, effort and expertise to attach various sensors to the body. A device optimized for RMA should instead require little effort or expertise to operate and be able to rapidly obtain and consolidate as much information as possible. MouthLab is a battery powered hand-held device intended to acquire and evaluate many measurements s...
Source: Annals of Biomedical Engineering - January 21, 2015 Category: Biomedical Engineering Authors: Fridman GY, Tang H, Feller-Kopman D, Hong Y Tags: Ann Biomed Eng Source Type: research

IEEE Transactions on Biomedical Engineering Handling Editors
(Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - January 20, 2015 Category: Biomedical Engineering Source Type: research

Motion Estimation in Cardiac Fluorescence Imaging With Scale-Space Landmarks and Optical Flow: A Comparative Study
This study is focused on methods for identifying landmarks and tracking the motion of cardiac tissue for preparations in optical mapping recordings. This is a first step toward our long-term goal to implement a landmark-based image registration technique to correct for pixel misalignment in cardiac optical mapping fluorescence videos and, hence, for gross motion artifacts. Preliminary results for the registration step are presented as an initial proof of concept. The characteristics of the optical mapping images are challenging, since their lack of contrast and well-defined features impose a limitation on the techniques th...
Source: IEEE Transactions on Biomedical Engineering - January 20, 2015 Category: Biomedical Engineering Source Type: research

Computer-Aided Diagnosis of Mammographic Masses Using Scalable Image Retrieval
Computer-aided diagnosis of masses in mammograms is important to the prevention of breast cancer. Many approaches tackle this problem through content-based image retrieval techniques. However, most of them fall short of scalability in the retrieval stage, and their diagnostic accuracy is, therefore, restricted. To overcome this drawback, we propose a scalable method for retrieval and diagnosis of mammographic masses. Specifically, for a query mammographic region of interest (ROI), scale-invariant feature transform (SIFT) features are extracted and searched in a vocabulary tree, which stores all the quantized features of pr...
Source: IEEE Transactions on Biomedical Engineering - January 20, 2015 Category: Biomedical Engineering Source Type: research

IEEE Transactions on Biomedical Engineering information for authors
(Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - January 20, 2015 Category: Biomedical Engineering Source Type: research

Monitoring Cerebral Hemodynamics Following Optogenetic Stimulation via Optical Coherence Tomography
In this article, spectral domain optical coherence tomography is used to measure the hemodynamic response induced by optogenetic stimulation in the somatosensory cortex of transgenic mice. By analyzing the 3-D angiograms and Doppler measurements produced by coherence tomography, we observed significant increase in blood flow as a result of increased vessel diameter and blood velocity following optical stimulation of cortical neurons. Such distinct responses were not observed in control experiments where the brain of wild-type mice were exposed to the same light pulses. (Source: IEEE Transactions on Biomedical Engineering)
Source: IEEE Transactions on Biomedical Engineering - January 20, 2015 Category: Biomedical Engineering Source Type: research

An Anatomically Detailed Arterial Network Model for One-Dimensional Computational Hemodynamics
Simulation platforms are increasingly becoming complementary tools for cutting-edge cardiovascular research. The interplay among structural properties of the arterial wall, morphometry, anatomy, wave propagation phenomena, and ultimately, cardiovascular diseases continues to be poorly understood. Accurate models are powerful tools to shed light on these open problems. We developed an anatomically detailed computational model of the arterial vasculature to conduct 1-D blood flow simulations to serve as simulation infrastructure to aid cardiovascular research. An average arterial vasculature of a man was outlined in 3-D spac...
Source: IEEE Transactions on Biomedical Engineering - January 20, 2015 Category: Biomedical Engineering Source Type: research