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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 9.

Defining human dendritic cell progenitors by multiparametric flow cytometry
Nature Protocols 10, 1407 (2015). doi:10.1038/nprot.2015.092 Authors: Gaëlle Breton, Jaeyop Lee, Kang Liu & Michel C Nussenzweig Human dendritic cells (DCs) develop from progressively restricted bone marrow (BM) progenitors: these progenitor cells include granulocyte, monocyte and DC progenitor (GMDP) cells; monocyte and DC progenitor (MDP) cells; and common DC progenitor (CDP) and DC precursor (pre-DC) cells. These four DC progenitors can be (Source: Nature Protocols)
Source: Nature Protocols - August 20, 2015 Category: Biomedical Science Authors: Gaëlle BretonJaeyop LeeKang LiuMichel C Nussenzweig Tags: Protocol Source Type: research

The Envelope of Motion of the Cervical Spine and its Influence on the maximum torque generating capability of the Neck Muscles
The posture of the head and neck is critical for predicting and assessing the risk of injury during high accelerations, such as those arising during motor accidents or in collision sports. Current knowledge suggests that the head’s range-of-motion (ROM) and the torque-generating capability of neck muscles are both dependent and affected by head posture. A deeper understanding of the relationship between head posture, ROM and maximum torque-generating capability of neck muscles may help assess the risk of injury and develop means to reduce such risks. (Source: Journal of Biomechanics)
Source: Journal of Biomechanics - August 20, 2015 Category: Biomedical Science Authors: Sorin Siegler, Paolo Caravaggi, James Tangorra, Mary Milone, Ramya Namani, Paul A. Marchetto Source Type: research

The natural immunity to evolutionary atavistic endotoxin for human cancer
We propose a new theory of the immunological control of cancer corresponding to the hypothesis that the specific natural immunity to evolutionary atavistic endotoxin has a potential role in human cancer prevention. The results of our studies have shown that IgMNAE, i.e. endogenous or spontaneous IgM class antibodies to enterobacterial lipopolysaccharide molecules (lipid A), control the immune mechanisms responsible for the internal medium stability not only against the damaging impact of the carcinogenic factors, but also against the malignant transformation of its own degenerated cells. (Source: Medical Hypotheses)
Source: Medical Hypotheses - August 20, 2015 Category: Biomedical Science Authors: Elena Moncevičiūtė-Eringienė, Kristina Rotkevič, Ruta Grikienyte Grikienis Tags: Correspondence Source Type: research

Decreased effectiveness of ischemic heart preconditioning in the state of chronic inflammation
There is growing evidence, that beneficial effects of ischemic heart preconditioning (IPC) may be lost or limited due to diabetes, hyperlipidemia, hypertension, atherosclerosis, heart failure and senility. It is plausible, that these conditions interfere with the biochemical pathways underlying the IPC response, but the detailed explanation is not clear.Pro-inflammatory cytokines (IL-1β, IL-6, TNF-α), monocyte chemotactic protein-1 (MCP-1), histamine and many others agents used in a single dose before prolonged ischemia mimic IPC. (Source: Medical Hypotheses)
Source: Medical Hypotheses - August 20, 2015 Category: Biomedical Science Authors: M. Wojciechowska, M. Zarębiński, P. Pawluczuk, D. Szukiewicz Source Type: research

Advanced Glycation End Products: A Link between Metabolic and Endothelial Dysfunction in Polycystic Ovary Syndrome?
Polycystic ovary syndrome (PCOS), a heterogeneous syndrome of reproductive and metabolic alterations, is associated with increased long-term risk of cardiovascular complications. This phenomenon has been linked to an increase in oxidative stress and inflammatory markers. Advanced glycation end products (AGEs) are pro-inflammatory molecules that trigger a state of intracellular oxidative stress and inflammation after binding to their cell membrane receptors RAGE. The activation of the AGE-RAGE axis has been well known to play a role in atherosclerosis in both men and women. (Source: Metabolism - Clinical and Experimental)
Source: Metabolism - Clinical and Experimental - August 20, 2015 Category: Biomedical Science Authors: Magdalena Pertynska-Marczewska, Evanthia Diamanti-Kandarakis, John Zhang, Zaher Merhi Source Type: research

Utilization of biodiesel by-products for mosquito control
Publication date: Available online 18 August 2015 Source:Journal of Bioscience and Bioengineering Author(s): Megha Pant, Satyawati Sharma, Saurabh Dubey, Satya Narayan Naik, Phool Kumar Patanjali The current paper has elaborated the efficient utilization of non-edible oil seed cakes (NEOC), by-products of the bio-diesel extraction process to develop a herbal and novel mosquitocidal composition against the Aedes aegypti larvae. The composition consisted of botanical active ingredients, inerts, burning agents and preservatives; where the botanical active ingredients were karanja (Pongamia glabra) cake powder and jatro...
Source: Journal of Bioscience and Bioengineering - August 20, 2015 Category: Biomedical Science Source Type: research

Isolation and analysis of polysaccharide showing high hyaluronidase inhibitory activity in Nostochopsis lobatus MAC0804NAN
Publication date: Available online 18 August 2015 Source:Journal of Bioscience and Bioengineering Author(s): Yuji Yamaguchi, Mamoru Koketsu An active substance with high hyaluronidase inhibitory effect was isolated from the edible cyanobacterium Nostochopsis lobatus MAC0804NAN strain and characterized. The active component in the hot water extract was purified by anion exchange and gel filtration chromatography and was found to be a polysaccharide. The IC50 against hyaluronidase of the purified polysaccharide was 7.18 μg/ml whose inhibitory activity is 14.5 times stronger than that of disodium cromoglycate (DSCG), an...
Source: Journal of Bioscience and Bioengineering - August 20, 2015 Category: Biomedical Science Source Type: research

Plasma Homocysteine, Vitamin B12 and Folate Levels in Multiple System Atrophy: A Case-Control Study
Conclusion Our data suggest that higher levels of Hcy may be associated with an increased risk for MSA. (Source: PLoS One)
Source: PLoS One - August 20, 2015 Category: Biomedical Science Authors: Shuyu Zhang et al. Source Type: research

Epithelial–Mesenchymal Transition in Kidney Tubular Epithelial Cells Induced by Globotriaosylsphingosine and Globotriaosylceramide
This study suggested that increased plasma lyso-Gb3 has a crucial role in the development of renal fibrosis through the cell-specific induction of the EMT in Fabry disease, and that TRI treatment, alongside enzyme replacement therapy, could be a potential therapeutic option for patients with Fabry disease. (Source: PLoS One)
Source: PLoS One - August 20, 2015 Category: Biomedical Science Authors: Yeo Jin Jeon et al. Source Type: research

Sleep Quality and Emotional Correlates in Taiwanese Coronary Artery Bypass Graft Patients 1 Week and 1 Month after Hospital Discharge: A Repeated Descriptive Correlational Study
Conclusion Sleep quality, anxiety and depression all significantly improved 1 month after hospital discharge. However, more than half of the participants continued to have poor sleep quality and some level of depression. Health care personnel should be encouraged to assess sleep and emotional status in patients after coronary artery bypass surgery and offer them appropriate management strategies to improve sleep and reduce anxiety and depression. (Source: PLoS One)
Source: PLoS One - August 20, 2015 Category: Biomedical Science Authors: Pei-Lin Yang et al. Source Type: research

Neural Basis of Psychological Growth following Adverse Experiences: A Resting-State Functional MRI Study
by Takashi X. Fujisawa, Minyoung Jung, Masahiko Kojima, Daisuke N. Saito, Hirotaka Kosaka, Akemi Tomoda Over the past decade, research on the aftereffects of stressful or traumatic events has emphasized the negative outcomes from these experiences. However, the positive outcomes deriving from adversity are increasingly being examined, and such positive changes are described as posttraumatic growth (PTG). To investigate the relationship between basal whole-brain functional connectivity and PTG, we employed resting-state functional magnetic resonance imaging and analyzed the neural networks using independent component analy...
Source: PLoS One - August 20, 2015 Category: Biomedical Science Authors: Takashi X. Fujisawa et al. Source Type: research

Generation of a Tph2 Conditional Knockout Mouse Line for Time- and Tissue-Specific Depletion of Brain Serotonin
by Barbara Pelosi, Marta Pratelli, Sara Migliarini, Giulia Pacini, Massimo Pasqualetti Serotonin has been gaining increasing attention during the last two decades due to the dual function of this monoamine as key regulator during critical developmental events and as neurotransmitter. Importantly, unbalanced serotonergic levels during critical temporal phases might contribute to the onset of neuropsychiatric disorders, such as schizophrenia and autism. Despite increasing evidences from both animal models and human genetic studies have underpinned the importance of serotonin homeostasis maintenance during central nervous sy...
Source: PLoS One - August 20, 2015 Category: Biomedical Science Authors: Barbara Pelosi et al. Source Type: research

Single Doses up to 800 mg of E-52862 Do Not Prolong the QTc Interval – A Retrospective Validation by Pharmacokinetic-Pharmacodynamic Modelling of Electrocardiography Data Utilising the Effects of a Meal on QTc to Demonstrate ECG Assay Sensitivity
Conclusion The sensitivity of this study to detect small changes in the QTc interval was confirmed by demonstrating a shortening of QTcF of -8.1 (90% CI: -10.4, -5.9) one hour and -7.2 (90% CI: -9.4, -5.0) three hours after a standardised meal. Trial Registration EU Clinical Trials Register EudraCT 2010 020343 13 (Source: PLoS One)
Source: PLoS One - August 20, 2015 Category: Biomedical Science Authors: Jörg Täubel et al. Source Type: research

Protection against the Metabolic Syndrome by Guar Gum-Derived Short-Chain Fatty Acids Depends on Peroxisome Proliferator-Activated Receptor γ and Glucagon-Like Peptide-1
In this study we investigated the molecular mechanism via which the dietary fiber guar gum protects against the metabolic syndrome. C57Bl/6J mice were fed a high-fat diet supplemented with 0% or 10% of the fiber guar gum for 12 weeks and effects on lipid and glucose metabolism were studied. We demonstrate that, like SCFAs, also guar gum protects against high-fat diet-induced metabolic abnormalities by PPARγ repression, subsequently increasing mitochondrial uncoupling protein 2 expression and AMP/ATP ratio, leading to the activation of AMPK and culminating in enhanced oxidative metabolism in both liver and adipose tissue. ...
Source: PLoS One - August 20, 2015 Category: Biomedical Science Authors: Gijs den Besten et al. Source Type: research

Serum HER2 Is a Potential Surrogate for Tissue HER2 Status in Gastric Cancer: A Systematic Review and Meta-Analysis
by Kecheng Zhang, Jianxin Cui, Hongqing Xi, Shibo Bian, Liangang Ma, Weisong Shen, Jiyang Li, Ning Wang, Bo Wei, Lin Chen Determining the expression level of human epidermal growth factor receptor 2 (HER2) in tumor tissue is of great importance for personalized therapy in gastric cancer. Although several studies have investigated whether serum HER2 can serve as a surrogate for tissue HER2 status, results have been inconsistent. We therefore performed a meta-analysis of published clinical studies in an attempt to address this problem. PubMed, Embase, Web of Science, the Cochrane Library and Science Direct were queried for ...
Source: PLoS One - August 20, 2015 Category: Biomedical Science Authors: Kecheng Zhang et al. Source Type: research

Heart Rate and Heart Rate Variability in Dairy Cows with Different Temperament and Behavioural Reactivity to Humans
by Levente Kovács, Fruzsina Luca Kézér, János Tőzsér, Ottó Szenci, Péter Póti, Ferenc Pajor From the 1990s, extensive research was started on the physiological aspects of individual traits in animals. Previous research has established two extreme (proactive and reactive) coping styles in several animal species, but the means of reactivity with the autonomic nervous system (ANS) activity has not yet been investigated in cattle. The aim of this study was the characterization of cardiac autonomic activity under different conditions in cows with different individual characteristics. For this purpose, we investigated ...
Source: PLoS One - August 20, 2015 Category: Biomedical Science Authors: Levente Kovács et al. Source Type: research

Higher Frequency of NK and CD4+ T-Cells in Mucosa and Potent Cytotoxic Response in HIV Controllers
by Natalia Andrea Taborda, Sandra Milena González, Cristiam Mauricio Alvarez, Luis Alfonso Correa, Carlos Julio Montoya, María Teresa Rugeles HIV infection induces immune alterations, mainly in gut mucosa, where the main target cells reside. However, the evolution of the infection is variable among infected individuals, as evidenced by HIV controllers who exhibit low or undetectable viral load in the absence of treatment. The aim of this study was to evaluate the frequency, phenotype and activity of T and NK cells in peripheral blood and gut mucosa in a cohort of Colombian HIV controllers. Blood and gut biopsies were in...
Source: PLoS One - August 20, 2015 Category: Biomedical Science Authors: Natalia Andrea Taborda et al. Source Type: research

Sensitive determination of glucose in Dulbecco's Modified Eagle Medium by high-performance liquid chromatography with 1-phenyl-3-methyl-5-pyrazolone derivatization: application to gluconeogenesis studies.
In conclusion, this method has been showed to determine small amount of glucose in DMEM successfully, as well as lower limit of quantitation and better sensibility when comparing to common commercial glucose assay kits. This article is protected by copyright. All rights reserved. PMID: 26293694 [PubMed - as supplied by publisher] (Source: Biomedical Chromatography : BMC)
Source: Biomedical Chromatography : BMC - August 20, 2015 Category: Biomedical Science Authors: Ling Z, Xu P, Zhong Z, Wang F, Shu N, Zhang J, Tang X, Liu L, Liu X Tags: Biomed Chromatogr Source Type: research

Time-tuning cancer therapy.
PMID: 26298846 [PubMed - as supplied by publisher] (Source: Aging)
Source: Aging - August 20, 2015 Category: Biomedical Science Authors: Baldassarre G, Segatto I, Belletti B Tags: Aging (Albany NY) Source Type: research

Roles of CDKN1B in cancer?
PMID: 26298275 [PubMed - as supplied by publisher] (Source: Aging)
Source: Aging - August 20, 2015 Category: Biomedical Science Authors: Belletti B, Baldassarre G Tags: Aging (Albany NY) Source Type: research

Vaccines Licensed for Immunization and Distribution in the US with Supporting Documents
This list includes only vaccines for which supporting documents were provided and is arranged alphabetically by the proper name of the product. Information is provided for original product approvals, new indications, and the current package insert. For a complete list of approved vaccines, click the link under "Related Information" at the bottom of this page. (Source: What's New at CBER)
Source: What's New at CBER - August 19, 2015 Category: Biomedical Science Source Type: news

Expression of a single gene lets scientists easily grow hepatitis C virus in the lab
In devising a method to readily grow hepatitis C in the laboratory, scientists might have overcome a major hurdle for basic research into the virus and the disease it causes. More » (Source: The Rockefeller University Newswire)
Source: The Rockefeller University Newswire - August 19, 2015 Category: Biomedical Science Authors: pubaff Tags: Science News Charles Rice HCV hepatitis C immunology microbiology Mohsan Saeed SEC14L2 Virology Source Type: news

Meet an Aid Worker Behind the Ebola Response in Liberia
Last August, the Ebola crisis, which had been simmering for months, erupted into headlines across the U.S. as the World Health Organization declared the Ebola outbreak in West Africa a humanitarian emergency. Now, more than a year into the epidemic, tremendous progress has been made to halt Ebola's spread, but the risk of resurgence remains until there are zero cases of Ebola. The progress in stopping Ebola is due to the courage of organizations and individuals who were willing to stretch their capacities to the limit and rise to the challenge of helping Liberia, Sierra Leone and Guinea end the disease. Above all, we mus...
Source: Healthy Living - The Huffington Post - August 19, 2015 Category: Consumer Health Advice Source Type: news

Erratum to: Advantages of new technologies in oral mucosal surgery: an intraoperative comparison among Nd:YAG laser, quantic molecular resonance scalpel, and cold blade
(Source: Lasers in Medical Science)
Source: Lasers in Medical Science - August 19, 2015 Category: Laser Surgery Source Type: research

Arsenic Trioxide Activate Transcription of Heme Oxygenase-1 by Promoting Nuclear Translocation of NFE2L2.
Authors: Yue Z, Zhong L, Mou Y, Wang X, Zhang H, Wang Y, Xia J, Li R, Wang Z Abstract In a previous study, we found that induced expression of Heme Oxygenase-1 (HO-1) is responsible for the resistance of human osteosarcoma MG63 cells to the chemotherapeutic agent arsenic trioxide (ATO). The present study was aimed at investigating the molecular mechanisms underlying the induction of HO-1 that occurs after exposure of MG63 cells to ATO. First, using RT-QPCT and Western-blot, we found that ATO strongly induced the expression of heme oxygenase-1 (HO-1) in these human osteosarcoma cells. Then by analyzing HO-1 mRNA of ...
Source: International Journal of Medical Sciences - August 19, 2015 Category: Biomedical Science Tags: Int J Med Sci Source Type: research

The Association of BCG Vaccination with Atopy and Asthma in Adults.
CONCLUSIONS: We found a significant association between BCG scar and asthmatic status in Korean adults, although there was no significant association between either the presence or size of BCG scar and atopy. PMID: 26283887 [PubMed - in process] (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - August 19, 2015 Category: Biomedical Science Tags: Int J Med Sci Source Type: research

The Role of Autophagy in Kidney Inflammatory Injury via the NF-κB Route Induced by LPS.
In conclusion, impairment of autophagy ameliorates LPS-induced inflammation and decreases kidney injury. The accumulation of ubiquitinated IκB may be responsible for this effect. PMID: 26283886 [PubMed - in process] (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - August 19, 2015 Category: Biomedical Science Tags: Int J Med Sci Source Type: research

Regulatory and Effector Helper T-Cell Profile after Nerve Xenografting in the Toll-Like Receptor-Deficient Mice.
CONCLUSIONS: TLR signaling is involved in T cell population regulation during tissue transplantation. Knock-out of TLR2 and NF-κB prevented Tregs elimination and inhibited Th1- and Th17-driven immune response after nerve xenografting. This study highlighted the potential of inhibiting TLR signaling to modulate T cell-mediated immune regulation to facilitate tolerance to nerve transplantation. PMID: 26283885 [PubMed - in process] (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - August 19, 2015 Category: Biomedical Science Tags: Int J Med Sci Source Type: research

A Randomized Clinical Trial of Nefopam versus Ketorolac Combined With Oxycodone in Patient-Controlled Analgesia after Gynecologic Surgery.
CONCLUSION: Nefopam showed a similar efficacy and lower incidence of nausea within 6 h after the operation to that of ketorolac in PCA. Nefopam may be a useful analgesic drug for the opioid-based PCA after gynecologic surgery. Further evaluation of accurate equivalent dose of nefopam as well as pharmacokinetics of bolus administration is required. PMID: 26283884 [PubMed - in process] (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - August 19, 2015 Category: Biomedical Science Tags: Int J Med Sci Source Type: research

Increased Expressions of Integrin Subunit β1, β2 and β3 in Patients with Acute Infection.
CONCLUSION: As the core proteins of venous thrombi, integrinβ1, β2 and β3 were markedly increased expression in patients with acute infection, which maybe explain the increased risk of VTE in acute infection patients. A weakened immune system could be the basic condition of VTE occurrence. PMID: 26283883 [PubMed - in process] (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - August 19, 2015 Category: Biomedical Science Tags: Int J Med Sci Source Type: research

Risk Factors of Myopic Shift among Primary School Children in Beijing, China: A Prospective Study.
CONCLUSION: Greater shift towards myopia was independently associated with modifiable factors (distance from near-work and longer time outdoors for leisure) might suggest that encouraging children to go outside for outdoor activities during class recess and after school may be a promising and feasible intervention against myopia development. PMID: 26283882 [PubMed - in process] (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - August 19, 2015 Category: Biomedical Science Tags: Int J Med Sci Source Type: research

Preventing and Treating Hypoxia: Using a Physiology Simulator to Demonstrate the Value of Pre-Oxygenation and the Futility of Hyperventilation.
CONCLUSIONS: HumMod accurately simulates the physiological responses compared to published human studies of pre-oxygenation and varying post intubation minute ventilations, and it can be used over wider ranges of parameters than available in human studies and therefore available in the literature. PMID: 26283881 [PubMed - in process] (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - August 19, 2015 Category: Biomedical Science Tags: Int J Med Sci Source Type: research

Anemia as an Independent Predictor of Adverse Cardiac Outcomes in Patients with Atrial Fibrillation.
CONCLUSIONS: Hemoglobin is a useful parameter for predicting adverse cardiac events, and including hemoglobin may improve the prognostic prediction of conventional clinical and echocardiographic parameters in patients with AF. PMID: 26283880 [PubMed - in process] (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - August 19, 2015 Category: Biomedical Science Tags: Int J Med Sci Source Type: research

Relationship between the hs-CRP as non-specific biomarker and Alzheimer's disease according to aging process.
CONCLUSION: We assumed that neuroinflammation play a role in the pathogenesis of AD, but found no clinical evidence that microglia senescence underlies the microglia switch from neuroprotective in young brains to neurotoxic in aged brains. To clarify the role of microglia and aging in the pathogenesis of AD, future longitudinal studies involving a large cohort are required. PMID: 26283879 [PubMed - in process] (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - August 19, 2015 Category: Biomedical Science Tags: Int J Med Sci Source Type: research

Lifestyle and Risk of Hypertension: Follow-Up of a Young Pre-Hypertensive Cohort.
CONCLUSION: Healthy BMI (18.5-24.9 kg/m(2)) and sleep duration (6-8 h/day) were associated with a lower risk of the occurrence of hypertension in pre-hypertension patients. PMID: 26283878 [PubMed - in process] (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - August 19, 2015 Category: Biomedical Science Tags: Int J Med Sci Source Type: research

Incidence and Risk Factors of Acute Kidney Injury after Radical Cystectomy: Importance of Preoperative Serum Uric Acid Level.
CONCLUSIONS: AKI after radical cystectomy was a relatively common complication. Its independent risk factors were high preoperative serum uric acid concentration and long operation time. These observations can help to prevent AKI after radical cystectomy. PMID: 26283877 [PubMed - in process] (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - August 19, 2015 Category: Biomedical Science Tags: Int J Med Sci Source Type: research

Dysregulated Serum MicroRNA Expression Profile and Potential Biomarkers in Hepatitis C Virus-infected Patients.
CONCLUSION: HCV patients have a broad 'fingerprint' profile with dysregulated serum miRNAs compared with that in healthy controls. Among these, serum hsa-miR-122, miR-134, miR-424-3p, and miR-629-5p are identified as promising indication factors of the serum miRNA profile of HCV infection. Particularly, miR-122 could be one of serum biomarkers for early pathological process of HCV. However, more miRNA biomarkers and biological functions of these miRNAs require further investigation. PMID: 26283876 [PubMed - in process] (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - August 19, 2015 Category: Biomedical Science Tags: Int J Med Sci Source Type: research

Effects of Remifentanil Preconditioning on Osteoblasts under Hypoxia-Reoxygenation Condition.
CONCLUSIONS: Under hypoxia-reoxygenation conditions, remifentanil preconditioning enhanced the cell viability and maturation of osteoblasts, and stimulated the expression of proteins associated with osteoblast proliferation and differentiation of the osteoblast. Our results suggest that remifentanil may help in the treatment of bone stress injuries. PMID: 26283875 [PubMed - in process] (Source: International Journal of Medical Sciences)
Source: International Journal of Medical Sciences - August 19, 2015 Category: Biomedical Science Tags: Int J Med Sci Source Type: research

Directed evolution of xylose specific transporters to facilitate glucose‐xylose co‐utilization
This article is protected by copyright. All rights reserved (Source: Biotechnology and Bioengineering)
Source: Biotechnology and Bioengineering - August 19, 2015 Category: Biomedical Science Authors: Meng Wang, Chenzhao Yu, Huimin Zhao Tags: Article Source Type: research

Cationic guar gum orchestrated environmental synthesis for silver nano-bio-composite films
Publication date: 10 December 2015 Source:Carbohydrate Polymers, Volume 134 Author(s): Md Farooque Abdullah, Sumanta Kumar Ghosh, Sreyasree Basu, Arup Mukherjee This work is meant for environmentally friendly synthesis and functional evaluation of silver nanoparticles in a newer cationic guar biopolymer (GGAA). Assembly of molecules in lower size range (∼10nm) was attained in a biopolymer entrapped bottom–up synthesis. Guar gum is a filming biopolymer. Nanoparticles encaged in cationic guar (GGAgnC) were preserved as films for months without any significant effect on particle size, distribution or plasmonic inten...
Source: Carbohydrate Polymers - August 19, 2015 Category: Biomedical Science Source Type: research

Quince seed mucilage magnetic nanocomposites as novel bioadsorbents for efficient removal of cationic dyes from aqueous solutions
This study investigated the potential use of quince seed mucilage (QSM) as alternative bioadsorbents for methylene blue (MB) dye from aqueous solutions. This novel magnetic nanocomposite adsorbent (MNCA) based on QSM was synthesized by in situ formation of magnetic iron oxide nanoparticles into QSM solution. The MNCAs were characterized using FTIR, SEM, TEM, XRD, and VSM. Removal of MB was investigated by batch adsorption technique. The thermodynamic parameters suggest that the dye adsorption process is spontaneous and exothermic in nature. Moreover, the adsorbents showed high selectivity for the adsorption of cationic dye...
Source: Carbohydrate Polymers - August 19, 2015 Category: Biomedical Science Source Type: research

Bark derived submicron-sized and nano-sized cellulose fibers: From industrial waste to high performance materials
In this study, the use of bark as a natural source for the production of cellulose nanofibers has been explored for the first time. The fibrillation using bleached and unbleached cellulose fibers from the bark yielded sub-micron scale (<1μm) and nanoscale fibers (<100nm). Previous attempts to break the cross-linked lignin barrier to produce fibrillated submicron sized or nano sized cellulose fibers with high lignin content (>20%) have never been possible from any other sources. The maximum elastic modulus value of 15.6GPa and tensile strength value of 76MPa were obtained for the films made from fibril...
Source: Carbohydrate Polymers - August 19, 2015 Category: Biomedical Science Source Type: research

Pharmaceutical grade chondroitin sulfate: Structural analysis and identification of contaminants in different commercial preparations
In conclusion, our findings indicate that the composition of CS preparations not always corresponds to the manufacturers’ descriptions, and indicate that further characterization should be required for the registry and license of pharmaceutical grade CS. (Source: Carbohydrate Polymers)
Source: Carbohydrate Polymers - August 19, 2015 Category: Biomedical Science Source Type: research

A three-dimensionally chitin nanofiber/carbon nanotube hydrogel network for foldable conductive paper
We reported a highly conductive nanocomposite made with multiwalled carbon nanotubes (MWCNTs) and chitin nanofibers (ChNFs). The MWCNTs were dispersed into ChNFs by the simple process of vacuum-filtration, forming a three-dimensional network structure. In this approach, MWCNT acted as a filler to introduce electron channel paths throughout the ChNF skeleton. And then, a hybrid hydrogel system (20wt.% NaOH, −18°C) was applied to prepare the ChNF/MWCNT gel-film followed with drying process. It is found that the resultant ChNF/MWCNT gel-film exposed much more MWCNT areas forming denser structure due to the shrinking of ChN...
Source: Carbohydrate Polymers - August 19, 2015 Category: Biomedical Science Source Type: research

Modified hydroxyethyl starch protects cells from oxidative damage
This article describes the synthesis of novel starch-antioxidant conjugates, which show great potential for biomedical applications to protect cells from oxidative damage. These conjugates were synthesized by the modification of a hydroxyethyl starch (molecular weight=200,000g/mol) with various sterically hindered phenols that differ in radical scavenging activity. They possess substantial radical scavenging activity toward a model free radical. It was found that the polymer conjugate conformation depends on the antioxidant structure and degree of substitution. We constructed the complete conformational phase behavior for ...
Source: Carbohydrate Polymers - August 19, 2015 Category: Biomedical Science Source Type: research

Agro-industrial residue from starch extraction of Pachyrhizus ahipa as filler of thermoplastic corn starch films
Publication date: 10 December 2015 Source:Carbohydrate Polymers, Volume 134 Author(s): O.V. López, F. Versino, M.A. Villar, M.A. García Biocomposites films based on thermoplastic corn starch (TPS) containing 0.5% w/w fibrous residue from Pachyrhizus ahipa starch extraction (PASR) were obtained by melt-mixing and compression molding. PASR is mainly constituted by remaining cell walls and natural fibers, revealed by Scanning Electron Microscopy (SEM). Chemical composition of the residue indicated that fiber and starch were the principal components. Biocomposites thermo-stability was determined by Thermo-Gravimetric A...
Source: Carbohydrate Polymers - August 19, 2015 Category: Biomedical Science Source Type: research

Dental plaque as a biofilm and a microbial community – implications for treatment
Conclusion An appreciation of ecological principles can lead to new strategies for treatment by identifying and removing the factors that drive dysbiosis, while actively supporting the growth of the natural oral microbiota. Also, the beneficial activities of the resident oral microbiota are retained and the risk of dysbiosis is reduced. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - August 19, 2015 Category: Biomedical Science Source Type: research

Chemotherapeutic effect of a novel temozolomide analog on nasopharyngeal carcinoma in vitro and in vivo
Conclusion: Our results demonstrate anticancer activity of NEO212 in preclinical NPC models, suggesting that this novel compound should be evaluated further for the treatment of patients with NPC. (Source: Journal of Biomedical Science)
Source: Journal of Biomedical Science - August 19, 2015 Category: Biomedical Science Authors: Thomas ChenHee-Yeon ChoWeijun WangStephanie WetzelAnupam SinghJenny NguyenFlorence HofmanAxel Schönthal Source Type: research

Proximal caries lesion detection in primary teeth: does this justify the association of diagnostic methods?
Abstract The aim of this clinical study was to evaluate and compare the performance of visual exam with use of the Nyvad criteria (visual examination - (VE)), interproximal radiography (BW), laser fluorescence device (DIAGNOdent Pen-DDPen), and their association in the diagnosis of proximal lesions in primary teeth. For this purpose, 45 children (n = 59 surfaces) of both sexes, aged between 5 and 9 years were selected, who presented healthy primary molars or primary molars with signs suggestive of the presence of caries lesions. The surfaces were clinically evaluated and coded according to the Nyvad criteria ...
Source: Lasers in Medical Science - August 19, 2015 Category: Laser Surgery Source Type: research