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This page shows you the 20 most read items in the past 30 days within this specialty in the MedWorm directory.

Affinity maturation generates greatly improved xyloglucan-specific carbohydrate binding modulesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: We conclude that affinity maturation of CBM selected from molecular libraries based on the CBM4-2 scaffold is possible and has the potential to generate new analytical tools for detection of plant carbohydrates. (Source: BMC Biotechnology - Latest articles)
Source: BMC Biotechnology - Latest articles - October 31, 2009 Category: Biotechnology Authors: Laura von SchantzFredrika GullfotSebastian ScheerLada FilonovaLavinia Cicortas GunnarssonJames FlintGeoffrey DanielEva Nordberg-KarlssonHarry BrumerMats Ohlin Source Type: journals

Dermaseptins and Magainins: Antimicrobial Peptides from Frogs' Skin—New Sources for a Promising Spermicides Microbicides—A Mini Reviewemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Sexually transmitted infections (STIs) and human immunodeficiency virus (HIV), the causative agents of acquired immunodeficiency syndrome (AIDS), are two great concerns in the reproductive health of women. Thus, the challenge is to find products with a double activity, on the one hand having antimicrobial/antiviral properties with a role in the reduction of STI, and on the other hand having spermicidal action to be used as a contraceptive. In the absence of an effective microbicide along with the disadvantages of the most commonly used spermicidal contraceptive worldwide, nonoxynol-9, new emphasis has been focused on the d...
Source: Journal of Biomedicine and Biotechnology - November 4, 2009 Category: Biotechnology Source Type: journals

Medtronic receives FDA warning letteremail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Medtronic Inc. announced Wednesday that it received a warning letter from the U.S. Food and Drug Administration following an August inspection of the company’s Cardiac Rhythm Disease Management facility in Mounds View. (MDT) (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - November 18, 2009 Category: Biotechnology Source Type: journals

East Bay's Alta Bates Medical Group picks Brown & Toland for management servicesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Alta Bates Medical Group, a 600-physician IPA based in Berkeley, is replacing its current management services organization next spring with San Francisco’s Brown & Toland Physicians, the groups said late Wednesday afternoon. (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - November 12, 2009 Category: Biotechnology Source Type: journals

Tennessee health ranking improves, but obesity loomsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Left unchecked, Tennessee’s obesity epidemic will cost the state $7.08 billion in health care spending over the next decade. That’s $1,442 for every adult, whether obese or not. (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - November 18, 2009 Category: Biotechnology Source Type: journals

Genetic load and transgenic mitigating genes in transgenic Brassica rapa (field mustard) x Brassica napus (oilseed rape) hybrid populationsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: The effects of genetic load of crop and in some situations, weed alleles might be beneficial under certain environmental conditions. However, when genetic load was directly incorporated into transgenic events, e.g., using a TM construct, the number of transgenic hybrids and persistence in weedy genomic backgrounds was significantly decreased. (Source: BMC Biotechnology - Latest articles)
Source: BMC Biotechnology - Latest articles - October 31, 2009 Category: Biotechnology Authors: Christy RoseReginald MillwoodHong Seok MoonMurali RaoMatthew HalfillPaul RaymerSuzanne WarwickHani Al-AhmadJonathan GresselC Neal Stewart Source Type: journals

Tight Junctions: A Barrier to the Initiation and Progression of Breast Cancer?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Breast cancer is a complex and heterogeneous disease that arises from epithelial cells lining the breast ducts and lobules. Correct adhesion between adjacent epithelial cells is important in determining the normal structure and function of epithelial tissues, and there is accumulating evidence that dysregulated cell-cell adhesion is associated with many cancers. This review will focus on one cell-cell adhesion complex, the tight junction (TJ), and summarize recent evidence that TJs may participate in breast cancer development or progression. We will first outline the protein composition of TJs and discuss the functions of ...
Source: Journal of Biomedicine and Biotechnology - November 15, 2009 Category: Biotechnology Source Type: journals

Jennerex inks deal with Lee’s Pharmaceutical Holdings in Chinaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Cancer medicine company Jennerex Inc. signed a deal with Lee’s Pharmaceutical Holdings Ltd. for development and sales of its lead drug. (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - November 18, 2009 Category: Biotechnology Source Type: journals

A Significant Increase of RNAi Efficiency in Human Cells by the CMV Enhancer with a tRNAlys Promoteremail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
RNA interference (RNAi) is the process of mRNA degradation induced by double-stranded RNA in a sequence-specific manner. Different types of promoters, such as U6, H1, tRNA, and CMV, have been used to control the inhibitory effect of RNAi expression vectors. In the present study, we constructed two shRNA expression vectors, respectively, controlled by tRNAlys and CMV enhancer-tRNAlys promoters. Compared to the vectors with tRNAlys or U6 promoter, the vector with a CMV enhancer-tRNAlys promoter silenced pokemon more efficiently on both the mRNA and the protein levels. Meanwhile, the silencing of pokemon inhibited the prolif...
Source: Journal of Biomedicine and Biotechnology - October 25, 2009 Category: Biotechnology Source Type: journals

Industry group launches AZBioLinkemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Just weeks into his new role as president and CEO of the Arizona BioIndustry Association, Robert Green already is making an impact on the state’s life sciences industry. (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - October 31, 2009 Category: Biotechnology Source Type: journals

Four-year sentence in Medicare fraudemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
A Miami man arrested in June on charges he laundered money in a scheme to defraud Medicare was sentenced on Friday to four years behind bars. (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - October 30, 2009 Category: Biotechnology Source Type: journals

HCA hires Joseph Sowell III as V.P. in charge of mergers and aquisitionsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
HCA Inc. announced today that Joseph Sowell III will become senior vice president and chief development officer, effective Dec. 1. (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - November 18, 2009 Category: Biotechnology Source Type: journals

Endo paying $23M to settle patent dispute with LecTecemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Endo Pharmaceuticals said late Wednesday that it will pay $23 million to intellectual property licensing and holding company LecTec Corp. to settle a patent dispute. (ENDP) (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - November 12, 2009 Category: Biotechnology Source Type: journals

GTx’s stock slides before conference callemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
GTx Inc. announced today that it will host a conference call and webcast at 10 a.m. (central) on Monday, Nov. 2, to provide an update regarding the New Drug Application for toremifene 80 mg to reduce fractures in men with prostate cancer on androgen deprivation therapy. (GTXI) (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - October 30, 2009 Category: Biotechnology Source Type: journals

Molecular Insight inks Onalta deals abroademail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Drug developer Molecular Insight Pharmaceuticals said Friday it has inked two, 10-year licensing and production deals for its cancer-therapy target Onalta. (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - October 23, 2009 Category: Biotechnology Source Type: journals

Potentia reaches deal to license drug to Alconemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Potentia Pharmaceuticals, a Louisville-based startup biotechnology company, has reached an agreement to license an age-related macular degeneration drug it is working on to Alcon Research Ltd., a Swiss pharmaceutical company that focuses on eye-care products. (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - October 23, 2009 Category: Biotechnology Source Type: journals

Meridian’s 4Q profits rise, beat outlookemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The H1N1 flu epidemic helped Meridian Bioscience to record sales and profits for its fourth quarter and fiscal year. (VIVO) (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - November 12, 2009 Category: Biotechnology Source Type: journals

Continucare buys two sleep disorder centersemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Continucare Corp. acquired two sleep diagnostic centers from Sleep Disorder Solutions. (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - October 23, 2009 Category: Biotechnology Source Type: journals

The Prominent Role of Neutrophils during the Initial Phase of Infection by Leishmania Parasitesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Neutrophils are rapidly and massively recruited to the site of Leishmania inoculation, where they phagocytose the parasites, some of which are able to survive within these first host cells. Neutrophils can thus provide a transient safe shelter for the parasites, prior to their entry into macrophages where they will replicate. In addition, neutrophils release and synthesize rapidly several factors including cytokines and chemokines. The mechanism involved in their rapid recruitment to the site of parasite inoculation, as well as the putative consequences of their massive presence on the microenvironment of the focus of infe...
Source: Journal of Biomedicine and Biotechnology - October 25, 2009 Category: Biotechnology Source Type: journals

Ignite Institute for Individualized Health to move to Fairfax Countyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Virginia leaders will announce Monday that the Ignite Institute for Individualized Health, a new personalized medicine research institute, plans to make Fairfax County its new home, according to sources close to the deal. (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - November 12, 2009 Category: Biotechnology Source Type: journals