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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 23.

Head And Neck Cancers: Common Genetic Alteration May Not Be Key To Effective Treatment
Although a large majority of head and neck cancers have a deregulation of the PI3K/AKT/mTOR pathway, data recently published in Cancer Research, a journal of the American Association for Cancer Research, indicated that deregulation of this pathway does not necessarily signify that the tumor is dependent on it for survival and progression. Cancer, particularly of the head and neck, is highly heterogeneous, with a large number of genetic alterations rendering it resistant to specific targeted treatments...
Source: Health News from Medical News Today - January 31, 2013 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news

Late Diagnosis Of Cancer Symptoms More Likely In UK Due To Worry And Embarrassment
Embarrassment and not wanting to waste their doctors' time are more frequently reported by British people than in other countries, according to new research led jointly by King's College London and UCL (University College London). This may be holding British people back from presenting early with symptoms of cancer...
Source: Health News from Medical News Today - January 31, 2013 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news

Women With BRCA Gene More Likely To Experience Early Menopause
Women with harmful mutations in the BRCA gene, which put them at higher risk of developing breast and ovarian cancer, tend to undergo menopause significantly sooner than other women, allowing them an even briefer reproductive window and possibly a higher risk of infertility, according to a study led by researchers at UC San Francisco. Moreover, the study showed that carriers of the mutation who are heavy smokers enter menopause at an even earlier age than non-smoking women with the mutation...
Source: Health News from Medical News Today - January 31, 2013 Category: Consumer Health News Tags: Menopause Source Type: news

Metabolism-Based Cancer Therapy May Be Useful For Non-Small Cell Lung Cancer
Ever since discovering a decade ago that a gene altered in lung cancer regulated an enzyme used in therapies against diabetes, Reuben Shaw has wondered if drugs originally designed to treat metabolic diseases could also work against cancer. The growing evidence that cancer and metabolism are connected, emerging from a number of laboratories around the world over the past 10 years, has further fueled these hopes, though scientists are still working to identify what tumors might be most responsive and which drugs most useful...
Source: Health News from Medical News Today - January 31, 2013 Category: Consumer Health News Tags: Lung Cancer Source Type: news

Morocco: HM King Mohammed VI Dedicates Cancer Treatment Center in Casablanca University Hospital
[MAP]Rabat, 30 -The dedication on Wednesday by HM King Mohammed VI, who was accompanied by HRH Princess Lalla Salma- chairwoman of « Lalla Salma Association for the struggle against cancer », of the Mohammed VI cancer treatment center at the Ibn Rochd University hospital in Casablanca showcases the interest granted by the sovereign to improving hospitalization conditions of cancer patients and His permanent will to alleviate their sufferings.
Source: AllAfrica News: Health and Medicine - January 31, 2013 Category: African Health Source Type: news

aldesleukin, Proleukin
Title: aldesleukin, ProleukinCategory: MedicationsCreated: 6/8/1999 10:15:00 PMLast Editorial Review: 1/31/2013 12:00:00 AM
Source: MedicineNet Cancer General - January 31, 2013 Category: Cancer & Oncology Source Type: news

Soy Intake and Lung Cancer Risk in Women
I was reminded by a salivating reader that I'd stopped writing her favorite weekly column. Lung Cancer Foodie Friday. Each Friday I would share a recipe that may either help with lung cancer prevention (or prevention of recurrence), or help ease the side effects of lung cancer treatments (such as those nasty chemotherapy induced mouth sores and taste changes.)...Read Full Post
Source: About.com Lung Cancer - January 31, 2013 Category: Cancer & Oncology Source Type: news

Consumer Reports Weighs In on Cancer Screening
Source: Physician's First Watch current issue - January 31, 2013 Category: Primary Care Tags: Medical News Source Type: news

Bridging the gap- improving outcomes for women with ovarian cancer: results from the Target Ovarian Cancer Pathfinder Study (2012)
This report tracks progress made since the 2009 Pathfinder Study on key measures, defines actions and priorities, and sets ...
Source: NeLM - News - January 31, 2013 Category: Drugs & Pharmacology Source Type: news

Grand round: What is the optimal endocrine therapy for postmenopausal women with hormone receptor-positive early breast cancer?
Source: J Clin Oncol Area: News The Grand Rounds series in the Journal of Clinical Oncology is designed to place original reports published in the journal into clinical context. A case presentation is followed by a description of diagnostic and management challenges, a review of the relevant literature, and a summary of the authors' suggested management approaches.   The subject of the latest grand round is endocrine therapy for postmenopausal women with hormone receptor-positive early breast cancer, which covers their efficacy, safety, treatment duration, and differences between aromatase inhibitors.
Source: NeLM - News - January 31, 2013 Category: Drugs & Pharmacology Source Type: news

How Have You Supported a Loved One During Cancer
When my husband was diagnosed with cancer last year, I wanted to give him the support he needed throughout treatment. I was there for every appointment, surgery, and therapy treatment. I ensured his diet contained foods that would promote healing and were healthy. I changed dressings after surgery and helped him dress when he was too weak. As I write this now, I see I did a lot to support my husband, but at the time, I felt like it wasn't enough. When someone you love has cancer, you do everything it takes to make them a little more comfortable and to increase their quality of life....Read Full Post
Source: About.com Cancer - January 31, 2013 Category: Cancer & Oncology Source Type: news

Mutant gene gives pigeons fancy hairdos
(University of Utah) University of Utah researchers decoded the genetic blueprint of the rock pigeon, unlocking secrets about pigeons' Middle East origins, feral pigeons' kinship with escaped racing birds, and how mutations give pigeons traits like a fancy feather hairdo known as a head crest.
Source: EurekAlert! - Cancer - January 31, 2013 Category: Cancer & Oncology Source Type: news

Engineered oncolytic herpes virus inhibits ovarian and breast cancer metastases
(Public Library of Science) A genetically reprogrammed Herpes simplex virus (HSV) can cure metastatic diffusion of human cancer cells in the abdomen of laboratory mice, according to a new study published January 31 in the Open Access journal PLOS Pathogens. The paper reports on the collaborative research from scientists at the at the University of Bologna and specifically describes that the HSV converted into a therapeutic anticancer agent attacks breast and ovarian cancer metastases.
Source: EurekAlert! - Cancer - January 31, 2013 Category: Cancer & Oncology Source Type: news

Understanding 'master regulator' genes could lead to better cancer treatments
(Oklahoma Medical Research Foundation) A pair of genes work together as "master regulators" in cell division to keep the correct number of chromosomes in each daughter cell. Ipl1 and Mps1 work to hook and unhook chromosomes for proper DNA separation. The discovery could lead to better anti-cancer therapies.
Source: EurekAlert! - Cancer - January 31, 2013 Category: Cancer & Oncology Source Type: news

Transition in cell type parallels treatment response, disease progression in breast cancer
(Massachusetts General Hospital) A process that normally occurs in developing embryos - the changing of one basic cell type into another - has also been suspected of playing a role in cancer metastasis. Now a study from Massachusetts General Hospital Cancer Center researchers has associated this process, called epithelial-mesenchymal transition or EMT, with disease progression and treatment response in breast cancer patients. The report also identifies underlying mechanisms that someday may become therapeutic targets.
Source: EurekAlert! - Cancer - January 31, 2013 Category: Cancer & Oncology Source Type: news

Blood vessel cells coax colorectal cancer cells into more dangerous state
(University of Texas M. D. Anderson Cancer Center) Blood vessels that supply oxygen and nutrients to tumors can also deliver something else - a signal that strengthens nearby cancer cells, making them more resistant to chemotherapy, more likely to spread to other organs and more lethal, scientists at the University of Texas MD Anderson Cancer Center report online in Cancer Cell.
Source: EurekAlert! - Cancer - January 31, 2013 Category: Cancer & Oncology Source Type: news

Glazer receives grant to study light-activated cancer drugs
(University of Kentucky) University of Kentucky assistant professor of chemistry Edith "Phoebe" Glazer has received an American Cancer Society Research Scholar Grant for $715,000 over four years to continue her research into ruthenium-based cancer drugs. These compounds are less toxic to healthy cells than a similar and widely used inorganic drug.
Source: EurekAlert! - Medicine and Health - January 31, 2013 Category: Global & Universal Source Type: news

2-step immunotherapy attacks advanced ovarian cancer
(University of Pennsylvania School of Medicine) Most ovarian cancer patients are diagnosed with late stage disease that is unresponsive to existing therapies. In a new study, researchers from the Perelman School of Medicine at the University of Pennsylvania School of Medicine show that a two-step personalized immunotherapy treatment -- a dendritic cell vaccine using patients' own tumor followed by adoptive T cell therapy -- triggers anti-tumor immune responses in these type of patients. The investigators report on initial results of the approach this month in OncoImmunology.
Source: EurekAlert! - Medicine and Health - January 31, 2013 Category: Global & Universal Source Type: news

Early Menopause May Occur In Women with BRCA Gene
Women with harmful mutations in the BRCA gene, which put them at higher risk of developing breast and ovarian cancer, tend to undergo menopause significantly sooner than other women, allowing them an even briefer reproductive window and possibly a higher risk of infertility, according to a study led by researchers at UC San Francisco.
Source: UCSF Medical Center - January 31, 2013 Category: Universities & Medical Training Authors: webservices at ucsfhealth.org Source Type: news

How cancer cells rewire their metabolism to survive
(Sanford-Burnham Medical Research Institute) Many scientists have tried killing tumors by taking away their favorite food, a sugar called glucose. Unfortunately, this treatment approach not only fails to work, it backfires--glucose-starved tumors get more aggressive. In a study published January 31 in Cell, researchers at Sanford-Burnham Medical Research Institute discovered that the protein PKCz is responsible for this paradox. The research suggests that glucose depletion therapies might work, as long as the cancer cells produce PKCz.
Source: EurekAlert! - Medicine and Health - January 31, 2013 Category: Global & Universal Source Type: news

Study finds hormones can change the breast's genetic material
(Walter and Eliza Hall Institute) Melbourne scientists have discovered how female steroid hormones can make dramatic changes to the genetic material in breast cells, changes that could potentially lead to breast cancer.Researchers from the Walter and Eliza Hall Institute of Medical Research in Melbourne, Australia, have identified how pregnancy hormones send signals to critical molecules on the DNA to make changes in the epigenome. The epigenome is a series of chemical tags that modify DNA, controlling which genes are switched on and off.
Source: EurekAlert! - Medicine and Health - January 31, 2013 Category: Global & Universal Source Type: news

How the tilt of a cell-surface receptor prevents cancer
(Ludwig Institute for Cancer Research) Clear communication between cells is essential to every aspect of the body's internal function. But since cells can't talk, or send emails, how do they communicate? The answer, in a nutshell, is by dispatching signaling molecules that selectively bind to protein receptors on the outer surface of other cells with which they must "talk."
Source: EurekAlert! - Medicine and Health - January 31, 2013 Category: Global & Universal Source Type: news

1 of the key circuits in regulating genes involved in producing blood stem cells is deciphered
(IMIM (Hospital del Mar Medical Research Institute)) Researchers from the group on stem cells and cancer at Hospital del Mar Medical Research Institute have deciphered one of the gene regulation circuits which would make it possible to generate hematopoietic blood cells, i.e. blood tissue stem cells. This could benefit patients with leukemia or other diseases requiring a transplant who do not have compatible donors.
Source: EurekAlert! - Medicine and Health - January 31, 2013 Category: Global & Universal Source Type: news

A new mechanism that contributes to the evolution of cancer
This study demonstrates the existence of new fragile genomic sites responsible for chromosomal alterations in tumors. This novel mechanism explains up to 50 percent of the abnormalities associated with some types of leukemia.
Source: EurekAlert! - Medicine and Health - January 31, 2013 Category: Global & Universal Source Type: news

Time spent watching television is not associated with death among breast cancer survivors
(Springer) Spending a lot of time watching television after breast cancer diagnosis is not linked to death in these breast cancer survivors. It appears that after accounting for self-reported physical activity levels after diagnosis, sedentary behavior was not an independent risk factor for death. These findings by Stephanie George, from the National Cancer Institute, and her colleagues, are published online in Springer's Journal of Cancer Survivorship.
Source: EurekAlert! - Social and Behavioral Science - January 31, 2013 Category: Global & Universal Source Type: news

The potential of psilocybin to alleviate psychological distress in cancer patients is revealed
(New York University) A recently published book chapter, "Use of the Classic Hallucinogen Psilocybin for Treatment of Existential Distress Associated with Cancer," reviews the potential of a novel psychoactive drug, psilocybin, in alleviating the psychological and spiritual distress that often accompanies a life threatening cancer diagnosis.
Source: EurekAlert! - Social and Behavioral Science - January 31, 2013 Category: Global & Universal Source Type: news

Side Effects of Prostate Cancer Treatments Similar in Long Run: Study
Researchers comparing surgery, radiation therapy did find short-term differences in men's sexual, urinary, bowel problems
Source: The Doctors Lounge - Oncology - January 31, 2013 Category: Cancer & Oncology Authors: webmaster at doctorslounge.com Tags: Oncology, Pharmacy, Reproductive Medicine, Surgery, Urology, News, Source Type: news

Kenya: Support Children Livivng With Cancer By Buying Their Paintings
[The Star]Help support a needy child with cancer access treatment by buying a piece of their art. The Kenya cancer association has partnered with several schools and the village market to have an art auction as we mark world childhood cancer day on the 15th of February. The auction will end on the 20th of February.
Source: AllAfrica News: Health and Medicine - January 30, 2013 Category: African Health Source Type: news

Internet Support to Assist Cancer Patients With SymptomsInternet Support to Assist Cancer Patients With Symptoms
WebChoice is an Internet-based, interactive health communication application that allows cancer patients to monitor their symptoms -- and much more. Cancer Nursing
Source: Medscape Today Headlines - January 30, 2013 Category: Consumer Health News Tags: Nursing Journal Article Source Type: news

Breast Cancer Diagnosed by Tomosynthesis in Dense BreastsBreast Cancer Diagnosed by Tomosynthesis in Dense Breasts
This case study demonstrates that three-dimensional breast tomosynthesis shows promise in successfully detecting small cancers which are not visible with traditional mammography. Applied Radiology
Source: Medscape Today Headlines - January 30, 2013 Category: Consumer Health News Tags: Radiology Journal Article Source Type: news

Ramucirumab increased survival among patients with advanced gastric cancer
Source: HemOncToday.com - January 30, 2013 Category: Cancer & Oncology Source Type: news

Family history linked to contralateral breast cancer risk
Reiner AS. J Clin Oncol. 2012;doi:10.1200/JCO.2012.43.2013.
Source: HemOncToday.com - January 30, 2013 Category: Cancer & Oncology Source Type: news

New tool predicts late recurrence in breast cancer
Read the full story on MD Consult: New tool predicts late recurrence in breast cancer
Source: MD Consult: News: Top Stories - January 30, 2013 Category: Journals (General) Source Type: news

Prostate cancer study tracks long-term urinary, sexual and bowel function side effects
A new study comparing outcomes among prostate cancer patients treated with surgery versus radiotherapy found differences in urinary, bowel and sexual function after short-term follow-up, but those differences were no longer significant 15 years after initial treatment.
Source: ScienceDaily Headlines - January 30, 2013 Category: Science Source Type: news

Prostate Cancer Tx Side-Effects Study: New 15-Year Data Prostate Cancer Tx Side-Effects Study: New 15-Year Data
Men with localized prostate cancer who decide to have surgery or radiation will eventually experience problems with urinary, bowel, and sexual function, regardless of the treatment they choose. Medscape Medical News
Source: Medscape Today Headlines - January 30, 2013 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Functional Issues Similar with Surgery, RT for Prostate Cancer (CME/CE)
(MedPage Today) -- Men with localized prostate cancer have declines in sexual, urinary, and bowel function over time, whether they choose surgery or radiation therapy, data from a large cohort study showed.
Source: MedPage Today State Required CME - January 30, 2013 Category: Consumer Health News Source Type: news

Menopause sooner if women have cancer gene
SAN FRANCISCO, Jan. 30 (UPI) -- Women with mutations in the BRCA gene, which put them at higher risk of breast and ovarian cancer, tend to undergo menopause sooner, U.S. researchers say.
Source: Health News - UPI.com - January 30, 2013 Category: Consumer Health News Source Type: news

Current Concepts and Novel Targets in Pancreatic CancerCurrent Concepts and Novel Targets in Pancreatic Cancer
What are some of the most advanced and cutting-edge therapies on the market for the treatment of advanced pancreatic cancer? This new study gives a detailed overview of some of the options. Gut
Source: Medscape Today Headlines - January 30, 2013 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Slight risk of QT-interval prolongation found with two antidepressants
The risk seen at high doses of citalopram and escitalopram, but not a number of other antidepressants, could put patients at risk for malignant ventricular arrhythmias.
Source: theHeart.org - January 30, 2013 Category: Cardiology Source Type: news

RNA Fragments May Yield Rapid, Accurate Cancer Diagnosis
Fragments of RNA that cells eject in fatty droplets may point the way to a new era of cancer diagnosis, potentially eliminating the need for invasive tests in certain cases. [More]
Source: Scientific American Topic - Medical Technology - January 30, 2013 Category: Consumer Health News Tags: Health,Health,Mind & Brain,Technology,Medical Technology,Neurological Disorders,Neuroscience,Biotechnology,Biotechnology,Biology,More Science Source Type: news

Proton Therapy Overhyped for Prostate Cancer?Proton Therapy Overhyped for Prostate Cancer?
New studies find that costly proton radiation therapy has no benefit over standard IMRT, so why are some urologists still singing its praises? Dr. Gerald Chodak discusses the issues. Medscape Urology
Source: Medscape Today Headlines - January 30, 2013 Category: Consumer Health News Tags: Urology Commentary Source Type: news

Smokers Die About A Decade Earlier On Average
WebMD Medical News By Salynn Boyles Reviewed by Laura J. Martin, MD Jan. 23, 2013 — Women who smoke are now just as likely to die of lung cancer and other smoking-related diseases as men — and smokers of both sexes die, on average, about a decade earlier than non-smokers. These were among the findings from two major studies examining death rate trends among smokers published in The New England Journal of Medicine. “The studies highlight the fact that cigarette smoking remains a leading cause of death in the U.S.,” says Steven A. Schroeder, MD, who directs the Smoking Cessation Leadership Center at ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - January 30, 2013 Category: Consumer Health News Authors: mreal197 Tags: WebMD News Source Type: news

Hops, Key to Flavor in Beer, May Prove Useful in New Drugs
Substances obtained from the bitter compound might help treat diabetes, some cancers, researchers say
Source: The Doctors Lounge - Oncology - January 30, 2013 Category: Cancer & Oncology Authors: webmaster at doctorslounge.com Tags: Oncology, Pharmacy, Research, Diabetes, News, Source Type: news

Cancer Deaths Third Higher In Men Than Women In UK
A new report shows that men are more than one third (35%) more likely to die of cancer in the UK than women, and they are two-thirds (67%) more likely to die from the disease when sex-specific cancers such as prostate, testicular and ovarian cancers are excluded. The report, produced by Cancer Research UK, the Men's Health Forum and the National Cancer Intelligence Network, shows that in 2010, the rate per 100,000 deaths from cancer for men in the UK was 202; for women it was 147...
Source: Health News from Medical News Today - January 30, 2013 Category: Consumer Health News Tags: Men's Health Source Type: news

Silibinin, found in milk thistle, protects against UV-induced skin cancer
Milk thistle extract, silibinin, kills skin cells mutated by UVA radiation and protects against damage by UVB radiation -- thus protecting against UV-induced skin cancer and photo-aging, according to new research.
Source: ScienceDaily Headlines - January 30, 2013 Category: Science Source Type: news

UCLA findings buck conventional wisdom about how stress-response protein works
UCLA researchers, in a finding that runs counter to conventional wisdom, have discovered for the first time that a gene thought to express a stress-response protein in all cells that come under stress instead expresses the protein only in specific cell types.   The research team, from the Jules Stein Eye Institute at UCLA and the UCLA Division of Pulmonary and Critical Care Medicine, focused on αB-Crystallin, one of a class of molecules known as heat shock proteins, which are involved in the folding and unfolding of other proteins, helping them recover from stress so they can do their job.   The expression ...
Source: UCLA Newsroom: Health Sciences - January 30, 2013 Category: Universities & Medical Training Source Type: news

Gene Test IDs Riskiest Lung Cancers (CME/CE)
LOS ANGELES (MedPage Today) -- A genetic assay may pick out high-risk lung cancers among small tumors that are likely to be increasingly detected given new screening recommendations, a study found.
Source: MedPage Today Hematology/Oncology - January 30, 2013 Category: Hematology Source Type: news

Being a Stoic saved me from the curse of the British stiff upper lip | Jules Evans
Real Stoicism, as the ancients practised, is about understanding feelings, not repressing them – which can do real harmIs the British Stiff Upper Lip killing us? That theory was put forward this week in the British Journal of Cancer by researchers looking into why the British are less likely to report symptoms than other Europeans – and therefore less likely to survive cancer. The problem, the lead researcher Dr Lindsay Forbes suggests, may be that "we are more stoic and have a war-time mentality". This foray into the national psyche comes just weeks after Dr Phillip Lee, a GP and Tory MP, suggested that the NHS was bu...
Source: Guardian Unlimited Science - January 30, 2013 Category: Science Authors: Jules Evans Tags: Comment The Guardian Psychology Mental health Society UK news Science Comment is free Source Type: news

Uncertainty About Proton-Beam Radiotherapy LingersUncertainty About Proton-Beam Radiotherapy Lingers
For many indications, especially prostate cancer, the superiority of proton-beam radiotherapy over less costly therapies remains unproven. Medscape Medical News
Source: Medscape Medical News Headlines - January 30, 2013 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news