Cancer & Oncology 
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This page shows you the most recent publications within this specialty of the MedWorm directory.
512987 records returned
Multiengine Speech Processing Using SNR Estimator in Variable Noisy Environments
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We introduce a multiengine speech processing system that can detect the location and the type of audio signal in variable noisy environments. This system detects the location of the audio source using a microphone array; the system examines the audio first, determines if it is speech/nonspeech, then estimates the value of the signal to noise (SNR) using a Discrete-Valued SNR Estimator. Using this SNR value, instead of trying to adapt the speech signal to the speech processing system, we adapt the speech processing system to the surrounding environment of the captured speech signal. In this paper, we introduced the Discrete...
Source: Journal of Oncology - February 8, 2012 Category: Cancer & Oncology Source Type: research
Visual Field Loss Morphology in High- and Normal-Tension GlaucomaEmail this article to a colleague.
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Conclusions. These data suggested that there was no relevant difference in the pointwise analysis between NTG and HTG; however, when visual field areas were compared, no difference in paracentral areas was found between NTG and HTG, but superior nasal step and inferior and superior scotomata showed to be deeper in HTG than in NTG. (Source: Journal of Oncology)
Source: Journal of Oncology - February 8, 2012 Category: Cancer & Oncology Source Type: research
Microarray Analyses of Genes Differentially Expressed by Diet (Black Beans and Soy Flour) during Azoxymethane-Induced Colon Carcinogenesis in RatsEmail this article to a colleague.
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The objective of this study was to identify genes altered by carcinogen treatment in normal-appearing colonic mucosa and those attenuated by bean feeding. Ninety-five male F344 rats were fed control (AIN) diets upon arrival. At 4 and 5 weeks, rats were injected with AOM (15 mg/kg) or saline and one week later administered an AIN, BB-, or SF-based diet. Rats were sacrificed after 31 weeks, and microarrays were conducted on RNA isolated from the distal colonic mucosa. AOM treatment induced a number of genes involved in immunity, including several MHC II-associated antigens and innate defense genes (RatNP-3, Lyz2, Pla2...
Source: Journal of Oncology - February 8, 2012 Category: Cancer & Oncology Source Type: research
Electrical Properties of Rapidly Annealed Ir and Ir/Au Schottky Contacts on n-Type InGaNEmail this article to a colleague.
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The effect of annealing temperature on electrical characteristics of iridium (Ir) and iridium/gold (Ir/Au) Schottky contacts to n-type InGaN have been investigated by means of current-voltage (I-V) and capacitance-voltage (C-V) techniques. It is observed that the barrier height of Ir/n-InGaN and Au/Ir/n-InGaN Schottky diodes increases after annealing at 300∘C for 1 min in N2 ambient compared to the as-deposited. However, the barrier heights are found to be decreased somewhat after annealing at 500∘C for the both Ir and Ir/Au Schottky contacts. From the above observations, it is clear that the optimum a...
Source: Journal of Oncology - February 8, 2012 Category: Cancer & Oncology Source Type: research
Effects of Brugmansia arborea Extract and Its Secondary Metabolites on Morphine Tolerance and Dependence in MiceEmail this article to a colleague.
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The aim of the present study was to investigate, in vivo, the effect of a Brugmansia arborea extract (BRU), chromatographic fractions (FA and FNA), and isolated alkaloids on the expression and the acquisition of morphine tolerance and dependence. Substances were acutely (for expression) or repeatedly (for acquisition) administered in mice treated with morphine twice daily for 5 or 6 days, in order to make them tolerant or dependent. Morphine tolerance was assessed using the tail-flick test at 1st and 5th days. Morphine dependence was evaluated through the manifestation of withdrawal symptoms induced by naloxone injection a...
Source: Journal of Oncology - February 8, 2012 Category: Cancer & Oncology Source Type: research
Design and Optimization of a Millimetre Wave Compact Folded Magic-TEmail this article to a colleague.
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A millimetre wave-folded magic-T junction compensated with metal cone is designed using a particle swarm optimization (PSO) algorithm. An off-centred metallic frustum was used to enhance the bandwidth and a metallic post is used to compensate the mismatched E-arm. The geometrical parameters of the frustum and the post are optimized by PSO. The optimized magic-T for W-band application is designed and tested. The design features are simple in structure and easy to fabricate. The 2% bandwidth with centre frequency of 94 GHz and return loss less than −20 dB is achieved. (Source: Journal of Oncology)
Source: Journal of Oncology - February 8, 2012 Category: Cancer & Oncology Source Type: research
Spectral Distortion in Lossy Compression of Hyperspectral DataEmail this article to a colleague.
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Distortion allocation varying with wavelength in lossy compression of hyperspectral imagery is investigated, with the aim of minimizing the spectral distortion between original and decompressed data. The absolute angular error, or spectral angle mapper (SAM), is used to quantify spectral distortion, while radiometric distortions are measured by maximum absolute deviation (MAD) for near-lossless methods, for example, differential pulse code modulation (DPCM), or mean-squared error (MSE) for lossy methods, for example, spectral decorrelation followed by JPEG 2000. Two strategies of interband distortion allocation are compare...
Source: Journal of Oncology - February 8, 2012 Category: Cancer & Oncology Source Type: research
Factors That Influence HIV Risk among Hispanic Female Immigrants and Their Implications for HIV Prevention InterventionsEmail this article to a colleague.
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Hispanics are the fastest growing minority group in North Carolina with increasing incidence of HIV infection. Gender roles, cultural expectations, and acculturation of women may explain some of Hispanic women’s risks. The perspectives of Hispanic female immigrants and community-based providers were sought to identify services they offer, understand HIV risk factors, and support the adaptation of a best-evidence HIV behavioural intervention for Hispanic women. Two sets of focus groups were conducted to explicate risks and the opportunities to reach women or couples and the feasibility to conduct HIV prevention in an acce...
Source: Journal of Oncology - February 8, 2012 Category: Cancer & Oncology Source Type: research
Seasonal Changes in Testes Vascularisation in the Domestic Cat (Felis domesticus): Evaluation of Microvasculature, Angiogenic Activity, and Endothelial Cell ExpressionEmail this article to a colleague.
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The objective of this study was to understand the effect of seasonality on: (i) microvasculature of cat testes; (ii) angiogenic activity in testicular tissue in vitro; and (iii) testicular endothelial cells expression throughout the year. Testicular vascular areas increased in March and April, June and July, being the highest in November and December. Testes tissue differently stimulated in vitro angiogenic activity, according to seasonality, being more evident in February, and November and December. Even though CD143 expression was higher in December, smaller peaks were present in April and July. As changes in angiogenesi...
Source: Journal of Oncology - February 8, 2012 Category: Cancer & Oncology Source Type: research
ContentsEmail this article to a colleague.
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(Source: Lung Cancer)
Source: Lung Cancer - February 8, 2012 Category: Cancer & Oncology Source Type: research
Editorial BoardEmail this article to a colleague.
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(Source: Lung Cancer)
Source: Lung Cancer - February 8, 2012 Category: Cancer & Oncology Source Type: research
Repeat flexible sigmoidoscopy increases colorectal cancer detection rateEmail this article to a colleague.
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Repeat screening by flexible sigmoidoscopy after 3 to 5 years increases the detection of colorectal cancer or advanced adenoma by a quarter in women and by a third in men, show results of the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - February 8, 2012 Category: Cancer & Oncology Source Type: news
Living with rotationplasty—Quality of life in rotationplasty patients from childhood to adulthoodEmail this article to a colleague.
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ConclusionsThe assessment of QoL by the SF‐36 questionnaire was effective, and a correspondence was found between what emerged from the quantitative study and the contents of the interview. Knowing the strengths and weaknesses that were highlighted is indispensable for parents and operators when choosing among the various surgical options and to facilitate coming to terms with the injury and the “scars”. J. Surg. Oncol. 2012;105:331–336. © 2012 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology)
Source: Journal of Surgical Oncology - February 8, 2012 Category: Cancer & Oncology Authors: Cristiana ForniNoemi GaudenziMarina ZoliMarco ManfriniMaria Grazia BenedettiElettra PignottiPaolo Chiari Tags: Research Article Source Type: research
Does preoperative therapy optimize outcomes in patients with resectable pancreatic cancer?Email this article to a colleague.
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The objective of this study was to compare survival between all patients with radiographically resectable adenocarcinoma of the proximal pancreas who underwent preoperative chemoradiation therapy (PRE‐OP CRT) or surgical exploration first (SURGERY) with “intention to resect.” Pancreatic cancer patients who undergo resection after PREOP CRT live longer than patients who undergo resection without PREOP CRT, a difference that may be attributable to patient selection. We retrospectively identified 236 patients with pancreatic head adenocarcinoma seen between 1999 and 2007 with sufficient data to be confirmed medically an...
Source: Journal of Surgical Oncology - February 8, 2012 Category: Cancer & Oncology Authors: Katia T. PapalezovaDouglas S. TylerDan G. BlazerBryan M. ClaryTheodore N. PappasRebekah R. WhiteBrian G. CzitoChristopher G. WillettHerbert I. HurwitzHope E. Uronis Tags: Review Article Source Type: research
FDA Grants Imatinib (Gleevec) Full Approval for Adjuvant Treatment of GISTEmail this article to a colleague.
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The FDA has granted imatinib full approval as an adjuvant treatment following surgical removal of CD117-positive gastrointestinal stromal tumors in adult patients. This comes after results from a phase III trial showed that patients taking imatinib for 36 months had a 5-year overall survival of 92%, compared to 82% for those patients who took the drug for the standard 12 months of treatment. (Source: Cancer Network)
Source: Cancer Network - February 8, 2012 Category: Cancer & Oncology Source Type: news
The results of treatment of children with metastatic Wilms tumours (WT) in an African setting: Do liver metastases have a negative impact on survival?Email this article to a colleague.
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ConclusionsIn Africa liver metastases do not appear to worsen the prognosis of children with Stage IV WT. Despite the poor socio‐economic circumstances survival is comparable to other countries. Pediatr Blood Cancer © 2012 Wiley Periodicals, Inc. (Source: Pediatric Blood and Cancer)
Source: Pediatric Blood and Cancer - February 8, 2012 Category: Cancer & Oncology Authors: Daniel C. AronsonAshwini MaharajMohamed H. Sheik‐GafoorG.P. Hadley Tags: Research Article Source Type: research
Antiparkinsonian Mechanism of Electroconvulsive Therapy in MPTP-Lesioned Non-Human PrimatesEmail this article to a colleague.
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Neurodegenerative Dis (DOI:10.1159/000334497) (Source: Karger Publishers)
Source: Karger Publishers - February 8, 2012 Category: Cancer & Oncology Source Type: research
Evaluation of Neurodegeneration in a Mouse Model of Infantile Batten Disease by Magnetic Resonance Imaging and Magnetic Resonance SpectroscopyEmail this article to a colleague.
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Neurodegenerative Dis (DOI:10.1159/000334838) (Source: Karger Publishers)
Source: Karger Publishers - February 8, 2012 Category: Cancer & Oncology Source Type: research
APOE-Mimetic Peptides Reduce Behavioral Deficits, Plaques and Tangles in Alzheimer's Disease TransgenicsEmail this article to a colleague.
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Neurodegenerative Dis (DOI:10.1159/000334914) (Source: Karger Publishers)
Source: Karger Publishers - February 8, 2012 Category: Cancer & Oncology Source Type: research
The Gastrin-Releasing Peptide Receptor as a Marker of Dysplastic Alterations in Cervical Epithelial CellsEmail this article to a colleague.
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Oncology 2012;82:90-97 (DOI:10.1159/000335955) (Source: Karger Publishers)
Source: Karger Publishers - February 8, 2012 Category: Cancer & Oncology Source Type: research
Expression of Epidermal Growth Factors, erbBs, in the Nasal Mucosa of Patients with Chronic Hypertrophic RhinitisEmail this article to a colleague.
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ORL 2012;74:57-63 (DOI:10.1159/000335583) (Source: Karger Publishers)
Source: Karger Publishers - February 8, 2012 Category: Cancer & Oncology Source Type: research
Planned Neck Dissection before Combined Chemoradiation in Organ Preservation Protocol for N2-N3 of Supraglottic or Hypopharyngeal CarcinomaEmail this article to a colleague.
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ORL 2012;74:64-69 (DOI:10.1159/000333111) (Source: Karger Publishers)
Source: Karger Publishers - February 8, 2012 Category: Cancer & Oncology Source Type: research
Leptin in Anorexia and Cachexia SyndromeEmail this article to a colleague.
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Leptin is a product of the obese (OB) gene secreted by adipocytes in proportion to fat mass. It decreases food intake and increases energy expenditure by affecting the balance between orexigenic and anorexigenic hypothalamic pathways. Low leptin levels are responsible for the compensatory increase in appetite and body weight and decreased energy expenditure (EE) following caloric deprivation. The anorexia-cachexia syndrome is a complication of many chronic conditions including cancer, chronic obstructive pulmonary disease, congestive heart failure, chronic kidney disease, and aging, where the decrease in body weight and fo...
Source: Clinical and Developmental Immunology - February 8, 2012 Category: Allergy & Immunology Source Type: research
MOfinder: A Novel Algorithm for Detecting Overlapping Modules from Protein-Protein Interaction NetworkEmail this article to a colleague.
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In this study, a new method, MOfinder, was developed to detect overlapping modules in a protein-protein interaction (PPI) network. We demonstrate that our method is more accurate than other 5 methods. Then, we applied MOfinder to yeast and human PPI network and explored the overlapping information. Using the overlapping modules of human PPI network, we constructed the module-module communication network. Functional annotation showed that the immune-related and cancer-related proteins were always together and present in the same modules, which offer some clues for immune therapy for cancer. Our study around overlapping modu...
Source: Clinical and Developmental Immunology - February 8, 2012 Category: Allergy & Immunology Source Type: research
Targeting HLA class I expression to increase tumor immunogenicityEmail this article to a colleague.
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The dynamic interaction between the host immune system and growing cancer has been of central interest to the field of tumor immunology over the past years. Recognition of tumor‐associated antigens (TAA) by self‐HLA (human leukocyte antigen) class I‐restricted CD8+ T cells is a main feature in the detection and destruction of malignant cells. The discovery and molecular characterization of TAA has changed the field of cancer treatment and introduced a new era of cancer immunotherapy aimed at increasing tumor immunogenicity and T‐cell‐mediated anti‐tumor immunity. Unfortunately, while these new protocols of canc...
Source: Tissue Antigens - February 8, 2012 Category: Allergy & Immunology Authors: A. B. del CampoJ. CarreteroN. AptsiauriF. Garrido Source Type: research
The impact of lung cancer on patients and carers.Email this article to a colleague.
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This article aims to provide a brief review of the literature with regard to the impact of lung cancer on patients and their informal carers. Compared to other types of cancer, the distress associated with lung cancer has been found to be the most intense. Rather than focusing on symptoms in isolation recent emphasis regarding the symptom experience has been on symptoms clusters, as understanding these clusters may improve the management of ongoing and unrelieved symptoms. However, the disparities in methodology are significant barriers to producing comparable results, although recent efforts have been made to address thes...
Source: Chronic Respiratory Disease - February 8, 2012 Category: Respiratory Medicine Authors: Ellis J Tags: Chron Respir Dis Source Type: research
For Personalizing Cancer Therapy, Metabolic Profiles Are EssentialEmail this article to a colleague.
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One way to tackle a tumor is to take aim at the metabolic reactions that fuel their growth. But a report in the February Cell Metabolism, a Cell Press Publication, shows that one metabolism-targeted cancer therapy will not fit all. That means that metabolic profiling will be essential for defining each cancer and choosing the best treatment accordingly, the researchers say. The evidence comes from studies in mice showing that tumors' metabolic profiles vary based on the genes underlying a particular cancer and on the tissue of origin... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 8, 2012 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news
Early Signs Of Disease Detected By Metabolic 'Breathalyzer'Email this article to a colleague.
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The future of disease diagnosis may lie in a "breathalyzer"-like technology currently under development at the University of Wisconsin-Madison. New research published online in February in the peer-reviewed journal Metabolism demonstrates a simple but sensitive method that can distinguish normal and disease-state glucose metabolism by a quick assay of blood or exhaled air. Many diseases, including diabetes, cancer, and infections, alter the body's metabolism in distinctive ways... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 8, 2012 Category: Consumer Health News Tags: Medical Devices / Diagnostics Source Type: news
Key Finding In Stem Cell Self-RenewalEmail this article to a colleague.
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A University of Minnesota-led research team has proposed a mechanism for the control of whether embryonic stem cells continue to proliferate and stay stem cells, or differentiate into adult cells like brain, liver or skin. The work has implications in two areas. In cancer treatment, it is desirable to inhibit cell proliferation. But to grow adult stem cells for transplantation to victims of injury or disease, it would be desirable to sustain proliferation until a sufficient number of cells have been produced to make a usable organ or tissue... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 8, 2012 Category: Consumer Health News Tags: Stem Cell Research Source Type: news
More Accurate Diagnosis, Prognosis In Challenging Breast Cancer Cases Provided By PET TechniquesEmail this article to a colleague.
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In two new studies featured in the February issue of The Journal of Nuclear Medicine, researchers are revealing how molecular imaging can be used to solve mysteries about difficult cases of breast cancer. One article focuses on an imaging agent that targets estrogen receptors in estrogen receptor-positive breast cancer patients with formerly inconclusive assessments, and the second highlights a different imaging agent's ability to help predict the prognosis for patients undergoing chemotherapy for a very aggressive type of breast cancer... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 8, 2012 Category: Consumer Health News Tags: Breast Cancer Source Type: news
Patient Sensitivity To Important Drug Target In Deadly Brain Cancer PredictedEmail this article to a colleague.
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A recent discovery by Van Andel Research Institute (VARI) scientists enables the prediction of patient sensitivity to proposed drug therapies for glioblastoma - the most common and most aggressive malignant brain tumor in humans. The study, published in the Proceedings of the National Academy of Science, investigated glioblastoma models characterized by cell signaling activation and gene amplification for their susceptibility to inhibitors of both the human MET oncogene and the epidermal growth factor receptor (EFGR). An oncogene is a gene with the potential to cause cancer... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 8, 2012 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news
Zinc Control Mechanisms Could Be Key To Aggressive Breast Cancer TreatmentsEmail this article to a colleague.
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The body's control mechanisms for delivering zinc to cells could be key to improving treatment for some types of aggressive breast cancer. New research by Cardiff University and King's College London has identified the switch which releases zinc into cells, with important implications for a number of diseases. Zinc has long been known to play a vital part in human health. Too much zinc, or too little, can cause cell death. A growing body of evidence links zinc to disease states including neurodegeneration, inflammation, diabetes and cancer... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 8, 2012 Category: Consumer Health News Tags: Breast Cancer Source Type: news
Women Born To Older Mothers Have A Higher Risk Of Developing Breast CancerEmail this article to a colleague.
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A new study analyses the influence that certain birth and infancy characteristics have on mammographic density - an important indicator of breast cancer risk. The results reveal that women born to mothers aged over 39 years and women who were taller and thinner than the average girl prior to puberty have a higher breast density. This brings with it an increased risk of developing breast cancer... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 8, 2012 Category: Consumer Health News Tags: Breast Cancer Source Type: news
Men with low-risk prostate cancer may benefit from dutasteride, active surveillanceEmail this article to a colleague.
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Fleshner NE. Lancet. 2012;doi:10.1016/S0140-6736(11)61619-X. (Source: HemOncToday.com)
Source: HemOncToday.com - February 8, 2012 Category: Cancer & Oncology Source Type: news
After Outcry, Karen Handel Resigns From KomenEmail this article to a colleague.
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Karen Handel’s resignation came just days after the cancer foundation reversed its decision to cut funds to Planned Parenthood. (Source: NYT)
Source: NYT - February 8, 2012 Category: American Health Authors: By JENNIFER PRESTON Tags: Handel, Karen C Komen, Susan G, for the Cure Planned Parenthood Federation of America Breast Cancer Abortion Suspensions, Dismissals and Resignations Brinker, Nancy Goodman Source Type: news
After Outcry, Karen Handel Resigns From KomenEmail this article to a colleague.
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Karen Handel’s resignation came just days after the cancer foundation reversed its decision to cut funds to Planned Parenthood. (Source: NYT Health)
Source: NYT Health - February 8, 2012 Category: Consumer Health News Authors: By JENNIFER PRESTON Tags: Handel, Karen C Komen, Susan G, for the Cure Planned Parenthood Federation of America Breast Cancer Abortion Suspensions, Dismissals and Resignations Brinker, Nancy Goodman Source Type: news
Top9ColCanRiskFactorsEmail this article to a colleague.
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Many of the top nine colon cancer risk factors are things you can change. Take the steps needed for better health and eliminate many of your colon cancer risk factors, too. (Source: About.com Colon Cancer)
Source: About.com Colon Cancer - February 8, 2012 Category: Cancer & Oncology Authors: coloncancer.guide at about.com Tags: health Source Type: news
basics of lymphedemaEmail this article to a colleague.
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Lymphedema is swelling that occurs due to the accumulation of lymphatic fluid (also called lymph) in an arm, or sometimes a leg. Many people who've undergone treatment for breast cancer worry about developing lymphedema. What are the symptoms of lymphedema to be on the lookout for? Arm yourself with knowledge about who gets lymphedema, how it is diagnosed, and how it is treated. (Source: About.com Breast Cancer)
Source: About.com Breast Cancer - February 8, 2012 Category: Cancer & Oncology Authors: breastcancer.guide at about.com Tags: health Source Type: news
Overexpression of DNA damage-induced 45 alpha gene contributes to esophageal squamous cell cancer by promoter hypomethylationEmail this article to a colleague.
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Conclusion:
Overexpression of GADD45alpha gene is due to DNA hypomethylation in ESCC. GADD45alpha may be a protective factor in DDP chemotherapy for esophageal squamous cell carcinoma. (Source: Journal of Experimental and Clinical Cancer Research)
Source: Journal of Experimental and Clinical Cancer Research - February 8, 2012 Category: Cancer & Oncology Authors: Bao xiang WangBang Liang YinBin HeChen ChenMing ZhaoWei xing ZhangZhen Kun XiaYi zhi PanJing qun TangXin min ZhouNi Yin Source Type: research
Improving adherence to surveillance and screening recommendations for people with colorectal cancer and their first degree relatives: A randomized controlled trialEmail this article to a colleague.
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DiscussionResults of this study will contribute to the evidence base about effective strategies to a) improve adherence to surveillance recommendation for people with CRC; and b) improve adherence to screening recommendation for FDRs of people with CRC. The use of a population-based cancer registry to access the target population may have significant advantages in increasing the reach of the intervention. (Source: BMC Cancer)
Source: BMC Cancer - February 8, 2012 Category: Cancer & Oncology Authors: Mariko CareyRobert Sanson-FisherFinlay MacraeDavid HillCatherine D'EsteChristine PaulChristopher Doran Source Type: research
The role and function of cadherins in the mammary glandEmail this article to a colleague.
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Cadherins are transmembrane receptors that function through calcium-dependent homophilic and heterophilic interactions that provide cell-cell contact and communication in many different organ systems. In the mammary gland only a few of the cadherins that make up this large superfamily of proteins have been characterized. Frequently in metastatic breast cancer, the genes for cadherins are epigenetically silenced, mutated, or regulated differently. During epithelial mesenchymal transition, cadherins that are expressed normally in the epithelial cells are down regulated, while cadherins expressed in the mesenchyme are up reg...
Source: Breast Cancer Research - February 8, 2012 Category: Cancer & Oncology Authors: Jennifer AndrewsAlvin KimJulie Hens Source Type: research
Key signaling nodes in mammary gland development and cancer: Smad signal integration in epithelial cell plasticityEmail this article to a colleague.
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Smad proteins are the key intermediates of TGF-beta-signaling during development and in tissue homeostasis. Pertubations in TGF-beta/Smad signaling have been implicated in cancer, and other diseases. In the cell nucleus Smad complexes trigger cell type- and context-specific transcriptional programs, thereby transmitting and integrating signals from a variety of ligands of the TGF-beta-superfamily and other stimuli in the cell micro-environment. The actual transcriptional and biological outcome of Smad activation critically depends on the genomic integrity and the modification state of genome and chromatin of the cell. The ...
Source: Breast Cancer Research - February 8, 2012 Category: Cancer & Oncology Authors: Anders SundqvistPeter ten DijkeHans van Dam Source Type: research
Research partnership to improve treatments for cancer patientsEmail this article to a colleague.
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(Walter and Eliza Hall Institute) The Australian Cancer Research Foundation has committed $2 million towards the fit-out of two new cancer research laboratories at the Walter and Eliza Hall Institute. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 8, 2012 Category: Global & Universal Source Type: news
Prognostic value of bcl-2 and bax tumor cell expression in patients with non muscle-invasive bladder cancer receiving bacillus calmette-guerin immunotherapy.Email this article to a colleague.
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In conclusion, the expression of Bcl-2 and Bax in NMIBC could have a prognostic value in assessing the risk of recurrence after BCG immunotherapy. These findings require further investigations on larger cohort in order to ascertain new molecular markers of the response to BCG immunotherapy.
PMID: 22292735 [PubMed - in process] (Source: Ultrastructural Pathology)
Source: Ultrastructural Pathology - February 7, 2012 Category: Pathology Authors: Ajili F, Kaabi B, Darouiche A, Tounsi H, Kourda N, Chebil M, Manai M, Boubaker S Tags: Ultrastruct Pathol Source Type: research
Pilot study on evaluation of any correlation between MR perfusion (K(trans)) and diffusion (apparent diffusion coefficient) parameters in brain tumors at 3 Tesla.Email this article to a colleague.
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Conclusion: We found that irrespective of brain tumor type, there is an inverse correlation between ADC and K(trans). Our findings highlight an intricate relationship between vascular permeability and the tumor microenvironment, probably modulating and/or interacting with changes such as increased cellularity, ischemic insult and varying extracellular matrix composition.
PMID: 22275724 [PubMed - in process] (Source: Cancer Imaging)
Source: Cancer Imaging - February 7, 2012 Category: Radiology Authors: Chu JP, Mak HK, Yau KK, Zhang L, Tsang J, Chan Q, Ka-Kit Leung G Tags: Cancer Imaging Source Type: research
Diffuse pulmonary uptake on FDG-PET with normal CT diagnosed as intravascular large B-cell lymphoma: a case report and a discussion of the causes of diffuse FDG uptake in the lungs.Email this article to a colleague.
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Abstract
A 71-year-old woman was admitted to our hospital with asthenia, weight loss, fever, cognitive impairment and shortness of breath. Physical examination showed hemiparesis and cerebellar ataxia. There was no superficial lymphadenopathy. Blood tests showed raised levels of C-reactive protein and lactate dehydrogenase. Bone marrow aspiration and biopsy were negative. [(18)F]fluorodeoxyglucose (FDG)-positron emission tomography (PET)/computed tomography (CT) showed intense uptake within a right apical nodule and intense and diffuse uptake of FDG in the lungs without corresponding structural CT abnormality. Lung...
Source: Cancer Imaging - February 7, 2012 Category: Radiology Authors: Wagner T, Brechemier D, Dugert E, Le Guellec S, Julian A, Hitzel A, Beyne-Rauzy O Tags: Cancer Imaging Source Type: research
The emergence of diagnostic imaging technologies in breast cancer: discovery, regulatory approval, reimbursement, and adoption in clinical guidelines.Email this article to a colleague.
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Abstract
In this article, we trace the chronology of developments in breast imaging technologies that are used for diagnosis and staging of breast cancer, including mammography, ultrasonography, magnetic resonance imaging, computed tomography, and positron emission tomography. We explore factors that affected clinical acceptance and utilization of these technologies from discovery to clinical use, including milestones in peer-reviewed publication, US Food and Drug Administration approval, reimbursement by payers, and adoption into clinical guidelines. The factors driving utilization of new imaging technologies are ...
Source: Cancer Imaging - February 7, 2012 Category: Radiology Authors: Gold LS, Klein G, Carr L, Kessler L, Sullivan SD Tags: Cancer Imaging Source Type: research
Atypical lipomatous tumor with unusual extensive metaplastic ossification.Email this article to a colleague.
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We report a case of ALT/WDLPS with unusual extensive metaplastic bone formation without an element of dedifferentiated liposarcoma.
PMID: 22294061 [PubMed - in process] (Source: Cancer Imaging)
Source: Cancer Imaging - February 7, 2012 Category: Radiology Authors: Javery O, Jagannathan JP, Saboo SS, O'Regan K, Hornick JL, Ramaiya N Tags: Cancer Imaging Source Type: research
CT-based quantitative SPECT for the radionuclide (201)Tl: experimental validation and a standardized uptake value for brain tumour patients.Email this article to a colleague.
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Abstract
We have previously reported on a method for reconstructing quantitative data from (99m)Tc single photon emission computed tomography (SPECT) images based on corrections derived from X-ray computed tomography, producing accurate results in both experimental and clinical studies. This has been extended for use with the radionuclide (201)Tl. Accuracy was evaluated with experimental phantom studies, including corrections for partial volume effects where necessary. The quantitative technique was used to derive standardized uptake values (SUVs) for (201)Tl evaluation of brain tumours. A preliminary study was per...
Source: Cancer Imaging - February 7, 2012 Category: Radiology Authors: Willowson K, Bailey D, Schembri G, Baldock C Tags: Cancer Imaging Source Type: research
Risk of Death From Certain Breast Cancers May Rise With AgeEmail this article to a colleague.
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Research focused on estrogen-sensitive tumors; undertreatment might play a role, expert says (Source: Cancercompass News: Breast Cancer)
Source: Cancercompass News: Breast Cancer - February 7, 2012 Category: Cancer & Oncology Source Type: news
