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Comparable patency achieved with radial artery and saphenous vein graftsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Study findings indicate that radial artery vein grafts provide comparable patency to saphenous vein grafts at 1 year after coronary artery bypass graft surgery. (Source: MedWire News - Cardiology)
Source: MedWire News - Cardiology - March 19, 2010 Category: Cardiology Source Type: news

Editorial BoardEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: International Journal of Cardiology)
Source: International Journal of Cardiology - March 19, 2010 Category: Cardiology Source Type: journals

Effects of Chromium Picolinate on Glycemic Control and Kidney of the Obese Zucker RatEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Does chromium picolinate treatment of obese rats exacerbate renal abnormalities associated with dysglycemia? Nutrition and Metabolism (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - March 19, 2010 Category: Cardiology Tags: Pathology & Lab Medicine Source Type: info

To Continue or Discontinue Aspirin in the Perioperative Period: A Randomized, Controlled Clinical TrialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Learn more about the effects of perioperative aspirin for high-risk patients undergoing non-cardiac surgery. British Journal of Anaesthesia (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - March 19, 2010 Category: Cardiology Tags: Anesthesiology Source Type: info

Orthostatic Hypotension Predicts All-Cause Mortality and Coronary Events In Middle-Aged Individuals (The Malmö Preventive Project)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Links between orthostatic hypotension, cardiovascular disease, and mortality are clarified in this prospective analysis. European Heart Journal (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - March 19, 2010 Category: Cardiology Tags: Cardiology Source Type: info

Are Quality Improvements Associated With the Get With the Guidelines-Coronary Artery Disease (GWTG-CAD) Program Sustained Over Time?Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Guideline adherence can be associated with effects that are more than skin deep, as indicated through sustained clinical performance measures. American Heart Journal (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - March 19, 2010 Category: Cardiology Tags: Cardiology Source Type: info

Confusion persists over ICD/CRT-D recall, but hopes high for swift resolutionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Industry analysts have been rabidly trying to get to the bottom of the company's action since Monday, polling physicians and company reps to understand the reason for the "retrieval" notice and... For complete story visit theheart.org. (Source: theHeart.org)
Source: theHeart.org - March 19, 2010 Category: Cardiology Source Type: info

Inside This IssueEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
1169 Jeffrey S. Berger, Courtney O. Jordan, Donald Lloyd-Jones, Roger S. Blumenthal (Source: Journal of the American College of Cardiology)
Source: Journal of the American College of Cardiology - March 19, 2010 Category: Cardiology Tags: Frontmatter Source Type: journals

Statins in Acute Coronary Syndromes and Genetic InsightEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
This report is similar to the original PROVE IT–TIMI 22 (Pravastatin or Atorvastatin Evaluation and Infection Therapy–Thrombolysis In Myocardial Infarction 22) results and raises 3 additional questions of clinical importance. First, was the MACE benefit primarily in favor of carriers of the KIF6 polymorphism? Second, was the time to benefit shorter in carriers of the KIF6 polymorphism? And third, why were differences in LDL-C and hs-CRP levels not associated with clinical outcome? (Source: Journal of the American College of Cardiology)
Source: Journal of the American College of Cardiology - March 19, 2010 Category: Cardiology Authors: H. Robert Superko, Kathryn Momary, Spencer King Tags: Letters to the Editor Source Type: journals

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The letter from Drs. Amorim and Doenst regarding an interpretation of the data presented in our recent study () underscores the immense complexity of discerning the interplay between the metabolic syndrome, coronary artery disease (CAD), diabetes, and heart failure. (Source: Journal of the American College of Cardiology)
Source: Journal of the American College of Cardiology - March 19, 2010 Category: Cardiology Authors: Ethan J. Anderson, P. Darrell Neufer Tags: Letters to the Editor Source Type: journals

Alternative Interpretation of Mitochondrial Metabolic Changes in Atrial Tissue of Type II Diabetic Human HeartEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Anderson et al. () presented an elegant study in which they assessed the rates of substrate oxidation and reactive oxygen species production of atrial tissue from diabetic patients with normal ejection fraction undergoing coronary artery bypass graft. The authors observed reduced mitochondrial respiratory capacity with palmitoyl-L-carnitine and glutamate as substrate, but not with pyruvate and succinate, as well as augmented reactive oxygen species production in the diabetic group when compared with nondiabetic patients. They then suggested that the existence of myocardial insulin resistance may explain the observed defect...
Source: Journal of the American College of Cardiology - March 19, 2010 Category: Cardiology Authors: Paulo A. Amorim, Torsten Doenst Tags: Letters to the Editor Source Type: journals

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We thank Drs. Cameron and Dart for their interest in our work (). The main finding of our study was that augmentation pressure (ΔPAUG) accounts for the majority of the variance in central pulse pressure (cPP) and is unrelated to pulse wave velocity (PWV). In line with most authorities (including those providing the editorial accompanying our paper), we attributed ΔPAUG to wave reflection (). Drs. Cameron and Dart's “alternate” explanation of our data is based on the assumption that the ratio of femoral artery to abdominal aortic diameter (DFA) is a measure of wave reflection. Given that wave reflection depends on dis...
Source: Journal of the American College of Cardiology - March 19, 2010 Category: Cardiology Authors: Marina Cecelja, Phil Chowienczyk Tags: Letters to the Editor Source Type: journals

Determinants of Raised Pulse Pressure in WomenEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Cecelja et al. () conclude that increased wave reflection, not arterial stiffness, determines pulse pressure, including central pulse pressure (cPP), in women. They base this conclusion on regression analysis showing that the ratio of femoral to aortic diameter (DFA [assumed an index of central-peripheral artery discontinuity and hence of wave reflection]) was a significant determinant of pressure augmentation (ΔPaug) whereas pulse wave velocity (PWV [a measure of arterial stiffness]) was not. However, from Table 3 in their article (), it appears that DFA accounts for only ≈2% of variation in ΔPaug. In contrast, PWV ac...
Source: Journal of the American College of Cardiology - March 19, 2010 Category: Cardiology Authors: James Cameron, Anthony M. Dart Tags: Letters to the Editor Source Type: journals

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We appreciate Dr. Heusch for calling attention to our paper () and for his generous praise. We do, however, disagree with some comments in his letter. His letter says that we do not acknowledge the distinction between α2-adrenergic receptors (ARs) (microvascular) and α1-ARs (epicardial coronaries), the fact that α-vasoconstriction is limited to arteries with coronary artery disease, and that α2-mediated coronary vasoconstriction is more important than α1-mediated. (Source: Journal of the American College of Cardiology)
Source: Journal of the American College of Cardiology - March 19, 2010 Category: Cardiology Authors: Paul C. Simpson, Brian C. Jensen, Teresa De Marco, Philip M. Swigart, Marie-Eve Laden Tags: Letters to the Editor Source Type: journals

Alpha-Adrenergic Coronary Vasoconstriction in HumansEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
I read with interest the study of Jensen et al. () and the accompanying editorial (). Jensen et al. demonstrated the abundance of the α1D-adrenoceptor subtype on the mRNA and by radioligand binding on the protein level in epicardial coronary arteries of explanted healthy and diseased human hearts. This information is novel and potentially important for the development of more specific α-adrenoceptor blockers to treat hypertension and/or prostate hyperplasia. The accompanying editorial correctly emphasizes the importance of studies in human rather than animal tissue. The original study and the editorial, however, do not a...
Source: Journal of the American College of Cardiology - March 19, 2010 Category: Cardiology Authors: Gerd Heusch Tags: Letters to the Editor Source Type: journals

Newly Elected Members of the CollegeEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The following individuals were elected to membership in the American College of Cardiology in the category indicated in February 2010. Those elected to Fellowship have been invited to participate in the 59th Annual Convocation of the College which will be held March 15, 2010, in Atlanta, Georgia. (Source: Journal of the American College of Cardiology)
Source: Journal of the American College of Cardiology - March 19, 2010 Category: Cardiology Tags: ACC NEWS Source Type: journals

Coronary “Reverse” Steal Phenomenon: Secret Passageway Out of CastleEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 46-year-old man without significant previous medical history was admitted to our hospital with chest pain. His electrocardiogram revealed an anterior myocardial infarction, and he was immediately taken to the catheterization laboratory for emergent angiography. Angiography showed total occlusion of the left anterior descending artery immediately distal to first diagonal branch. Additionally, a coronary fistula stemming from the proximal circumflex artery and draining to pulmonary artery was noted (A, Online Video 1). We decided to treat the left anterior descending artery lesion, and balloon angioplasty with stenting was...
Source: Journal of the American College of Cardiology - March 19, 2010 Category: Cardiology Authors: Tolga Sinan Güvenç, Hatice Betül Erer, Zekeriya Nurkalem, Mehmet Eren Tags: IMAGES IN CARDIOLOGY Source Type: journals

Spontaneous Recanalization of a Coronary Artery After Thrombotic Occlusion: In Vivo Demonstration With Optical Coherence TomographyEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
A 50-year-old man with a recent embolic stroke was referred by a neurologist for abnormal electrocardiography results consistent with large anterior myocardial infarction. Echocardiogram results showed akinesis of the anteroapical left ventricular wall without obvious mural thrombus and an ejection fraction of 45%. There was no evidence of an intracardiac shunt. Coronary angiography revealed irregular linear filling defects in the mid left anterior descending artery (A) (line 1 and 2 indicate the length of optical coherence tomography pullback). Optical coherence tomography showed multiple channels surrounding a larger cen...
Source: Journal of the American College of Cardiology - March 19, 2010 Category: Cardiology Authors: Jin-Man Cho, Owen C. Raffel, James R. Stone, Chong-Jin Kim, Ik-Kyung Jang Tags: IMAGES IN CARDIOLOGY Source Type: journals

The National Heart, Lung, and Blood Institute Bench to Bassinet Program: A New Paradigm for Translational ResearchEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Congenital heart disease (CHD) is the most common birth defect and is a significant source of morbidity and mortality in children. Despite considerable recent progress in the clinical arena, we have a lot yet to learn about the causes of CHD and the genetic modifiers of clinical outcome. It is our hope that an improved understanding of the etiology of CHD will lead to improved care for the patient with this disease. To accelerate discovery in these areas, the National Heart, Lung, and Blood Institute (NHLBI) launched a novel translational research program in pediatric cardiovascular disease, the Bench to Bassinet program, ...
Source: Journal of the American College of Cardiology - March 19, 2010 Category: Cardiology Authors: Jonathan R. Kaltman, Charlene Schramm, Gail D. Pearson Tags: NEWS FROM THE NHLBI Source Type: journals

Improvement in Cardiac Function With Small Intestine Extracellular Matrix Is Associated With Recruitment of C-Kit Cells, Myofibroblasts, and Macrophages After Myocardial InfarctionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: We show for the first time that injection of EMU into the infarcted myocardium increases neovascularization and preserves cardiac function, potentially mediated by enhanced recruitment of c-kit–positive cells, myofibroblasts, and macrophages. (Source: Journal of the American College of Cardiology)
Source: Journal of the American College of Cardiology - March 19, 2010 Category: Cardiology Authors: Zhi-Qing Zhao, John D. Puskas, Di Xu, Ning-Ping Wang, Mario Mosunjac, Robert A. Guyton, Jakob Vinten-Johansen, Robert Matheny Tags: PRE-CLINICAL RESEARCH Source Type: journals

Effect of an Antimicrobial Agent on Atherosclerotic Plaques: Assessment of Metalloproteinase Activity by Molecular ImagingEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Molecular imaging of MMP activity in atherosclerotic plaque allows for the study of the efficacy of therapeutic interventions. MC administration resulted in substantial reduction in plaque MMP activity and histologically verified plaque stabilization. MC was found to be equally effective as FS. (Source: Journal of the American College of Cardiology)
Source: Journal of the American College of Cardiology - March 19, 2010 Category: Cardiology Authors: Satoru Ohshima, Shinichiro Fujimoto, Artiom Petrov, Hironori Nakagami, Nezam Haider, Jun Zhou, Nobuhiro Tahara, Mariana Kiomy Osako, Ai Fujimoto, Jie Zhu, Toyoaki Murohara, D. Scott Edwards, Navneet Narula, Nathan D. Wong, Y. Chandrashekhar, Ryuichi Moris Tags: PRE-CLINICAL RESEARCH Source Type: journals

Understanding Radiation-Induced Vascular Disease⁎Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Radiation injury of blood vessels was originally described more than a century ago and remains a contemporary clinical problem, despite dramatic advances in the field of radiation oncology (). Clinical studies indicate that patients who have previously undergone radiation therapy for various malignancies—such as lymphoma, breast cancer, and head and neck cancer—are at increased risk for developing vascular disease (). The consequences are significant; depending upon the study, the relative risk of suffering a clinical cardiovascular event (i.e., myocardial infarction, stroke) related to radiation therapy ranges from ap...
Source: Journal of the American College of Cardiology - March 19, 2010 Category: Cardiology Authors: Neal L. Weintraub, W. Keith Jones, David Manka Tags: Radiation Injury: Editorial Comment Source Type: journals

Sustained Inflammation Due to Nuclear Factor-Kappa B Activation in Irradiated Human ArteriesEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: In the present study, we found sustained inflammation due to NF-κB activation in human radiated arteries. The results are supported by previous in vitro findings suggesting that deoxyribonucleic acid injury, after radiation, activates NF-κB. We also suggest that HOXA9 might be involved in the regulation of NF-κB activation. The observed sustained inflammatory response can explain cardiovascular disease years after radiation. (Source: Journal of the American College of Cardiology)
Source: Journal of the American College of Cardiology - March 19, 2010 Category: Cardiology Authors: Martin Halle, Anders Gabrielsen, Gabrielle Paulsson-Berne, Caroline Gahm, Hanna E. Agardh, Filip Farnebo, Per Tornvall Tags: Radiation Injury Source Type: journals

Reverse Remodeling of the Atria After Treatment of Chronic Stretch in Humans: Implications for the Atrial Fibrillation SubstrateEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: The atrial electrophysiologic and electroanatomic abnormalities that result from chronic stretch due to MS reverses after MC. These observations suggest that the substrate predisposing to atrial arrhythmias might be reversed. (Source: Journal of the American College of Cardiology)
Source: Journal of the American College of Cardiology - March 19, 2010 Category: Cardiology Authors: Bobby John, Martin K. Stiles, Pawel Kuklik, Anthony G. Brooks, Sunil T. Chandy, Jonathan M. Kalman, Prashanthan Sanders Tags: Heart Rhythm Disorders Source Type: journals

Atorvastatin Causes Insulin Resistance and Increases Ambient Glycemia in Hypercholesterolemic PatientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Despite beneficial reductions in LDL cholesterol and apolipoprotein B, atorvastatin treatment resulted in significant increases in fasting insulin and glycated hemoglobin levels consistent with insulin resistance and increased ambient glycemia in hypercholesterolemic patients. (Effects of Atorvastatin on Adiponectin Levels and Insulin Sensitivity In Hypercholesterolemic Patients; NCT00745836) (Source: Journal of the American College of Cardiology)
Source: Journal of the American College of Cardiology - March 19, 2010 Category: Cardiology Authors: Kwang Kon Koh, Michael J. Quon, Seung Hwan Han, Yonghee Lee, Soo Jin Kim, Eak Kyun Shin Tags: Lipid Disorders Source Type: journals

Reperfusion Injury: Putting the Genie Back in the Bottle?⁎Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Genie: A supernatural creature which occupies a parallel world to that of mankind … Possessing free will, … can be either good or evil. —Wikipedia () In this issue of the Journal, Mewton et al. () describe a rare event: a negative study with potentially enormous impact. Their work, using cardiac magnetic resonance, demonstrates that administration of a single dose of cyclosporine at the time of percutaneous coronary intervention for ST-segment elevation myocardial infarction (STEMI), which prevents or reduces reperfusion injury, does not have adverse consequences for left ventricular (LV) remodeling in the post-infa...
Source: Journal of the American College of Cardiology - March 19, 2010 Category: Cardiology Authors: Nathaniel Reichek, Kambiz Parcham-Azad Tags: Myocardial Infarction: Editorial Comment Source Type: journals

Effect of Cyclosporine on Left Ventricular Remodeling After Reperfused Myocardial InfarctionEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Cyclosporine used at the moment of acute myocardial infarction reperfusion persistently reduces infarct size and does not have a detrimental effect on LV remodeling. These results are preliminary and must be supported by further studies. (Ciclosporin A and Acute Myocardial Infarction; NCT00403728) (Source: Journal of the American College of Cardiology)
Source: Journal of the American College of Cardiology - March 19, 2010 Category: Cardiology Authors: Nathan Mewton, Pierre Croisille, Gerald Gahide, Gilles Rioufol, Eric Bonnefoy, Ingrid Sanchez, Thien Tri Cung, Catherine Sportouch, Denis Angoulvant, Gérard Finet, Xavier André-Fouët, Geneviève Derumeaux, Christophe Piot, Hélène Vernhet, Didier Reve Tags: Myocardial Infarction Source Type: journals

Biomarker Bonanza?⁎Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In this issue of the Journal, Morrow et al. () from the TIMI Group, provide a provocative update of the MERLIN–TIMI 36 (Metabolic Efficiency With Ranolazine for Less Ischemia in Non-ST Elevation Acute Coronary–Thrombolysis In Myocardial Infarction 36) trial. Their report raises the possibility that a single measurement of plasma concentrations of B-type natriuretic peptide (BNP), taken early in the hospital course of patients with acute coronary syndrome (ACS), not only can identify a cohort at higher risk of poor clinical outcomes, but may also differentiate patients more likely to experience a reduction in recurrent ...
Source: Journal of the American College of Cardiology - March 19, 2010 Category: Cardiology Authors: Robert M. Califf, Svati H. Shah, L. Kristin Newby Tags: Myocardial Infarction: Editorial Comment Source Type: journals

B-Type Natriuretic Peptide and the Effect of Ranolazine in Patients With Non–ST-Segment Elevation Acute Coronary Syndromes: Observations From the MERLIN–TIMI 36 (Metabolic Efficiency With Ranolazine for Less Ischemia in Non-ST Elevation Acute Coronary–Thrombolysis In Myocardial Infarction 36) TrialEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: Our findings indicate that ranolazine may have enhanced efficacy in high-risk patients with ACS identified by increased BNP. The interaction of biomarkers of hemodynamic stress and the effects of ranolazine warrants additional investigation. (Metabolic Efficiency With Ranolazine for Less Ischemia in Non–ST Elevation Acute Coronary Syndromes; NCT00099788) (Source: Journal of the American College of Cardiology)
Source: Journal of the American College of Cardiology - March 19, 2010 Category: Cardiology Authors: David A. Morrow, Benjamin M. Scirica, Marc S. Sabatine, James A. de Lemos, Sabina A. Murphy, Petr Jarolim, Pierre Theroux, Christophe Bode, Eugene Braunwald Tags: Myocardial Infarction Source Type: journals

Impact of Stent Overlap on Angiographic and Long-Term Clinical Outcome in Patients Undergoing Drug-Eluting Stent ImplantationEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Conclusions: DES overlap occurs in >10% of patients undergoing percutaneous coronary intervention in routine clinical practice and is associated with impaired angiographic and long-term clinical outcome, including death or myocardial infarction. (Sirolimus-Eluting Versus Paclitaxel-Eluting Stents for Coronary Revascularization; NCT00297661). (Source: Journal of the American College of Cardiology)
Source: Journal of the American College of Cardiology - March 19, 2010 Category: Cardiology Authors: Lorenz Räber, Peter Jüni, Lukas Löffel, Simon Wandel, Stéphane Cook, Peter Wenaweser, Mario Togni, Rolf Vogel, Christian Seiler, Franz Eberli, Thomas Lüscher, Bernhard Meier, Stephan Windecker Tags: Interventional Cardiology Source Type: journals

Screening for Cardiovascular Risk in Asymptomatic PatientsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We describe 6 risk algorithms (Framingham Risk Score for coronary heart disease events and for cardiovascular events, Adult Treatment Panel III, SCORE [Systematic Coronary Risk Evaluation] project, Reynolds Risk Score, ASSIGN [Assessing Cardiovascular Risk to Scottish Intercollegiate Guidelines Network/SIGN to Assign Preventative Treatment], and QRISK [QRESEARCH Cardiovascular Risk Algorithm]) for outcomes, population derived/validated, receiver-operating characteristic, variables included, and limitations. Areas of uncertainty include 10-year versus lifetime risk, prediction of CVD or coronary heart disease end points, no...
Source: Journal of the American College of Cardiology - March 19, 2010 Category: Cardiology Authors: Jeffrey S. Berger, Courtney O. Jordan, Donald Lloyd-Jones, Roger S. Blumenthal Tags: STATE-OF-THE-ART PAPER Source Type: journals

ACC: Intensive Statin Tx Cuts CVEs in Kidney Disease Patients (CME/CE)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
ATLANTA (MedPage Today) -- Intensive statin therapy was associated with a marked decrease in cardiovascular events and a modest improvement in renal function among heart patients with metabolic syndrome complicated by chronic kidney disease, industry researchers reported here. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - March 19, 2010 Category: Cardiology Source Type: news

Broaden CRT indications to include mild heart failure, recommends FDA advisory panelEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
The panel unanimously recommended that cardiac resynchronization therapy indications be extended to include patients in NYHA functional class 1 or 2, with a few added twists aimed at excluding... For complete story visit theheart.org. (Source: theHeart.org)
Source: theHeart.org - March 19, 2010 Category: Cardiology Source Type: info

RA: Lowering Cardiovascular Risk With StatinsEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
In patients with rheumatoid arthritis, managing cardiovascular risk is as important as RA-specific therapy. Nature Reviews Rheumatology (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - March 19, 2010 Category: Cardiology Tags: Rheumatology Source Type: info

Journal Scan: Thoracic Aortic Aneurysm: Clinically Pertinent Controversies and Uncertainties (J Am Coll Cardiol 2010;55:841-857.)Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Cardiosource)
Source: Cardiosource - March 19, 2010 Category: Cardiology Source Type: organizations

Clinical Trial Of Minimally Invasive Stenting System For Carotid Arteries Available At Cedars-Sinai Medical CenterEmail this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Patients who suffer from plaque-related narrowing of a carotid artery but are not good candidates for open surgery may be eligible to participate in a clinical trial at Cedars-Sinai Medical Center of a minimally invasive procedure designed to open carotid arteries the way angioplasty and stenting clear arteries of the heart. The carotid arteries of the neck supply oxygenated blood to the brain... (Source: Cardiovascular / Cardiology News From Medical News Today)
Source: Cardiovascular / Cardiology News From Medical News Today - March 19, 2010 Category: Cardiology Tags: Heart Disease Source Type: news

Partial Anomalous Pulmonary Venous Return [IMAGES IN CARDIOTHORACIC MEDICINE AND SURGERY]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Asian Cardiovascular and Thoracic Annals)
Source: Asian Cardiovascular and Thoracic Annals - March 19, 2010 Category: Cardiology Authors: Hisatomi, Eishi, Hashizume, Miura, Taniguchi, Hashimoto Tags: IMAGES IN CARDIOTHORACIC MEDICINE AND SURGERY Source Type: journals

Mitral Insufficiency 30 Years after Resection of Subvalvular Aortic Stenosis [IMAGES IN CARDIOTHORACIC MEDICINE AND SURGERY]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Asian Cardiovascular and Thoracic Annals)
Source: Asian Cardiovascular and Thoracic Annals - March 19, 2010 Category: Cardiology Authors: Bustamante, Florez, Garcia-Moran, Bustamante, Gomez-Martinez, Tamayo Tags: IMAGES IN CARDIOTHORACIC MEDICINE AND SURGERY Source Type: journals

"Hotshot" into the Heart [IMAGES IN CARDIOTHORACIC MEDICINE AND SURGERY]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Asian Cardiovascular and Thoracic Annals)
Source: Asian Cardiovascular and Thoracic Annals - March 19, 2010 Category: Cardiology Authors: Ng, Wan, Underwood, Graham Tags: IMAGES IN CARDIOTHORACIC MEDICINE AND SURGERY Source Type: journals

Unruptured Noncoronary Sinus of Valsalva Aneurysm [IMAGES IN CARDIOTHORACIC MEDICINE AND SURGERY]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
(Source: Asian Cardiovascular and Thoracic Annals)
Source: Asian Cardiovascular and Thoracic Annals - March 19, 2010 Category: Cardiology Authors: Singh, Singhal Tags: IMAGES IN CARDIOTHORACIC MEDICINE AND SURGERY Source Type: journals

3-Dimensional Structures to Enhance Cell Therapy and Engineer Contractile Tissue [INVITED REVIEW]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Experimental studies in animals and recent human clinical trials have revealed the current limitations of cellular transplantation, which include poor cell survival, lack of cell engraftment, and poor differentiation. Evidence in animals suggests that use of a 3-dimensional scaffold may enhance cell therapy and engineer myocardial tissue by improving initial cell retention, survival, differentiation, and integration. Several scaffolds of synthetic or natural origin are under development. Until now, contractility has been demonstrated in vitro only in biological scaffolds prepared from decellularized organs or tissue, or in...
Source: Asian Cardiovascular and Thoracic Annals - March 19, 2010 Category: Cardiology Authors: Schussler, Chachques, Mesana, Suuronen, Lecarpentier, Ruel Tags: INVITED REVIEW Source Type: journals

Repair of Ventricular Septal Perforation after Inferior Myocardial Infarction [HOW TO DO IT]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Various techniques have been used for repair of ventricular septal perforation complicating inferior myocardial infarction, but no standard method has been established. An effective technique for closing ventricular septal perforation using double patches via a right atrial approach is described. In our experience, no residual shunt was observed after repair using this procedure. (Source: Asian Cardiovascular and Thoracic Annals)
Source: Asian Cardiovascular and Thoracic Annals - March 19, 2010 Category: Cardiology Authors: Yamamoto, Ohara, Nie, Torii, Inoue, Miyaji Tags: HOW TO DO IT Source Type: journals

Repair of Type A Aortic Dissection in Nonagenarian [CASE STUDIES]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We describe successful repair of type A aortic dissection with ascending aortic graft replacement, aortic valve repair, hemiarch reconstruction, and ablation of atrial fibrillation in a 93-year-old man. (Source: Asian Cardiovascular and Thoracic Annals)
Source: Asian Cardiovascular and Thoracic Annals - March 19, 2010 Category: Cardiology Authors: Woo, Kozin Tags: CASE STUDIES Source Type: journals

Tender Inflammatory Infrarenal Aortic Aneurysm Simulating Acute Rupture [CASE STUDIES]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We describe successful open graft repair of a tender inflammatory infrarenal abdominal aortic aneurysm simulating acute rupture in a 63-year-old man. (Source: Asian Cardiovascular and Thoracic Annals)
Source: Asian Cardiovascular and Thoracic Annals - March 19, 2010 Category: Cardiology Authors: Pang, Chan, Ting, Cheng Tags: CASE STUDIES Source Type: journals

Coronary Artery Graft Dilatation Aided by Multidetector Computed Tomography [CASE STUDIES]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We describe a successful case of percutaneous coronary intervention for occluded coronary artery bypass grafts with the aid of multidetector computed tomography. (Source: Asian Cardiovascular and Thoracic Annals)
Source: Asian Cardiovascular and Thoracic Annals - March 19, 2010 Category: Cardiology Authors: Song, Choi, Choi, Park, Park, Choe Tags: CASE STUDIES Source Type: journals

Surgery for Papillary Fibroelastoma with Uncommon Location in Left Ventricle [CASE STUDIES]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Cardiac papillary fibroelastoma is a rare tumor. Its location in the left ventricular wall is uncommon. A 59-year-old woman with 2 previous strokes presented with a tumor in the left ventricular apex. The patient underwent tumor resection through a left ventriculotomy. The histopathologic diagnosis was papillary fibroelastoma. (Source: Asian Cardiovascular and Thoracic Annals)
Source: Asian Cardiovascular and Thoracic Annals - March 19, 2010 Category: Cardiology Authors: Domenech, Perez de Arenaza, Garcia Rivello, Patrucco, Bracco Tags: CASE STUDIES Source Type: journals

Aprotinin Confers Neuroprotection by Reducing Apoptotic Cell Death [ORIGINAL ARTICLE]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Aprotinin has been used in pediatric cardiac surgery for its antiinflammatory and hemostatic benefits. We have reported that aprotinin has a direct cellular neuroprotective effect through reduction of excitotoxicity. The purpose of this study was to investigate whether aprotinin is neuroprotective against apoptotic cell death. Near-pure neuronal cultures containing <5% astrocytes were obtained from fetal mice. Serum deprivation was initiated at 7 days by transferring the cultures, which are dependent on serum for survival, into growth medium lacking serum for 24 h. Neuronal cell death was assessed by phase-contrast cell...
Source: Asian Cardiovascular and Thoracic Annals - March 19, 2010 Category: Cardiology Authors: Iwata, Nicole, Okamura, Zurakowski, Jonas Tags: ORIGINAL ARTICLE Source Type: journals

Lower Ministernotomy and Fast Tracking for Atrial Septal Defect [ORIGINAL ARTICLE]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
We report our experience with a 3–5-cm lower ministernotomy incision for closure of atrial septal defect in 53 patients. Fibrillatory arrest was used in 19 patients, and crossclamping with cardioplegia in 33. One patient had to be converted from fibrillatory arrest to crossclamping with cardioplegic arrest. The mean bypass time was 39.6 ± 13.1 min, arrest time was 9.9 ± 4.5 min, and crossclamp time was 20.7 ± 8.69 min. All patients recovered without adverse events. They were fast tracked to recovery and extubated after 63.4 ± 9.2 min. The mean intensive care unit stay was 1.07 ± 0.3...
Source: Asian Cardiovascular and Thoracic Annals - March 19, 2010 Category: Cardiology Authors: Karthekeyan, Vakamudi, Thangavelu, Sulaiman, Sundar, Kumar Tags: ORIGINAL ARTICLE Source Type: journals

Clamp-and-Sew Technique for Traumatic Injuries of the Aorta: 20-Year Experience [ORIGINAL ARTICLE]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Traumatic aortic injuries are associated with high morbidity and mortality, and the ideal operative approach for surgical management is unclear. We analyzed our results with the open clamp-and-sew technique over a 20-year period. Twenty patients with transected aorta were given interposition grafts; 19 of them had multisystem injuries. Mean aortic crossclamp time was 21.7 min (range, 12–30 min). Postoperative complications included pneumonia in 4 patients, acute renal failure in 1, recurrent laryngeal nerve injury in 2, chylothorax in 1, and sepsis of unknown etiology in one. There was no incidence of operation-relat...
Source: Asian Cardiovascular and Thoracic Annals - March 19, 2010 Category: Cardiology Authors: Bhaskar, Foo, Sharma Tags: ORIGINAL ARTICLE Source Type: journals

Mesothelial Cells vs. Skeletal Myoblasts for Myocardial Infarction [ORIGINAL ARTICLE]Email this article to a colleague. Save this article to My Clippings. Discuss or comment on this article.
Cell transplantation for the regeneration of ischemic myocardium is limited by poor graft viability and low cell retention. Omental flaps in association with growth factors and cell sheets have recently been used to increase the vascularization of ischemic hearts. This experimental study was undertaken to evaluate the hemodynamic evolution and histological modifications of infarcted myocardium treated with mesothelial cells, and to compare the results with those of hearts treated with skeletal myoblasts. Myocardial infarction was created by surgical ligature of 2 coronary branches in 34 sheep; 6 died immediately due to ven...
Source: Asian Cardiovascular and Thoracic Annals - March 19, 2010 Category: Cardiology Authors: Bourahla, Shafy, Meilhac, Elmadbouh, Michel, Chachques Tags: ORIGINAL ARTICLE Source Type: journals