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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 14.

When Children With Kawasaki Disease Grow Up: Myocardial and Vascular Complications in Adulthoodemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Kawasaki disease (KD) is an acute, self-limited vasculitis that typically occurs in young children and was first described by Japanese pediatrician Tomisaku Kawasaki in 1967. Although originally thought to be a rare condition, KD has become the most common cause of acquired heart disease in the pediatric age group in developed countries. The majority of patients with KD appear to have a benign prognosis, but a subset of patients with coronary artery aneurysms are at risk for ischemic events and require lifelong treatment. In the 4 decades that have passed since the initial recognition of KD, the number of patients reaching...
Source: Journal of the American College of Cardiology - November 12, 2009 Category: Cardiology Authors: John B. Gordon, Andrew M. Kahn, Jane C. Burns Tags: STATE-OF-THE-ART PAPERS Source Type: journals

The Adult After Kawasaki Disease: The Risks for Late Coronary Eventsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Under what circumstances should a transient childhood illness be considered a lifelong potential cardiac risk factor? Do all patients who have had Kawasaki disease (KD) require special follow-up, intermittent cardiac testing, and preventive measures beyond the American Heart Association (AHA) recommendations for all Americans? If not, which patients are at significant risk for late coronary events to justify being placed in a high-risk category? These are the questions that must be answered to recommend a careful follow-up régime for those who are at risk and to reassure the others. The impact of carrying a lifetime diagn...
Source: Journal of the American College of Cardiology - November 12, 2009 Category: Cardiology Authors: Welton M. Gersony Tags: Commentary Source Type: journals

Incidence and Predictors of Drug-Eluting Stent Fracture in Human Coronary Artery: A Pathologic Analysisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: The incidence of stent fracture was 29% lesions at autopsy, which is much higher than clinically reported. A high rate of adverse pathologic findings was observed in lesions with grade V stent fracture, whereas fracture with grade I to IV did not have a significant impact on the pathological outcome.
Source: Journal of the American College of Cardiology - November 12, 2009 Category: Cardiology Authors: Gaku Nakazawa, Aloke V. Finn, Marc Vorpahl, Elena Ladich, Robert Kutys, Isidora Balazs, Frank D. Kolodgie, Renu Virmani Tags: Interventional Cardiology Source Type: journals

Drug-Eluting Stent Fracture: Promise and Performance⁎email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
All promise outruns performance.—Ralph Waldo Emerson () The saga of drug-eluting stents (DES) continues from their hyperbolic introduction into clinical practice in 2003 through a period of scrupulous clinical safety introspection, emerging as the principal device therapy for percutaneous coronary intervention with renewed enthusiasm in today's era of prolonged oral dual antiplatelet therapy. Clinicians, researchers, industry, and regulatory agencies have gained wisdom from the many lessons taught in the global introduction of DES into clinical practice. As clinicians and scientists, we benefit from an organized cogniti...
Source: Journal of the American College of Cardiology - November 12, 2009 Category: Cardiology Authors: Andrew J. Carter Tags: Interventional Cardiology: Editorial Comment Source Type: journals

Effects of Angiotensin-Converting Enzyme Inhibitor Therapy on Clinical Outcome in Patients Undergoing Coronary Artery Bypass Graftingemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Can this study settle the controversy over whether preoperative use of ACE inhibitors is safe for patients undergoing CABG? Journal of the American College of Cardiology
Source: Medscape Cardiology Headlines - November 12, 2009 Category: Cardiology Tags: Cardiology Source Type: info

Journal Scan: Simple Versus Complex Stenting Strategy for Coronary Artery Bifurcation Lesions in the Drug-Eluting Stent Era: A Meta-Analysis of Randomised Trials (Heart 2009;95:1676-1681.)email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The authors performed a meta-analysis of trials comparing two strategies for DES treatment of coronary bifurcation lesions: a strategy of main branch stenting with provisional stenting of the side arm versus a strategy of routine stenting of main and side branch.
Source: Cardiosource - November 12, 2009 Category: Cardiology Source Type: organizations

For MRI Tracking Of Stem Cells, $1M In Stimulus Funds Awarded To Rice, Texas Heart Instituteemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The National Institutes of Health (NIH) has awarded researchers at Rice University and the Texas Heart® Institute (THI) a $1 million Challenge Grant to refine cell-tracking nanotube technology that could make magnetic resonance imaging (MRI) up to 40 times more sensitive than existing MRIs and help guide adult stem cells within the human body to repair damaged hearts.
Source: Cardiovascular / Cardiology News From Medical News Today - November 12, 2009 Category: Cardiology Tags: Cardiovascular / Cardiology Source Type: news

Federal Stimulus Grants Will Accelerate Health Research, Create Jobsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Academic Health Center scientists, physicians, and research centers have attracted 128 grants totaling nearly $35 million in federal stimulus money (as of Nov. 10) since the American Recovery and Reinvestment Act was approved in February 2009. This will result in a total economic impact of more than $105 million; according to the National Institutes of Health, $1 of research funding multiplies to more than $2 of goods and services in the economy.
Source: Cardiovascular / Cardiology News From Medical News Today - November 12, 2009 Category: Cardiology Tags: Alzheimer's / Dementia Source Type: news

NHLBI Publishes New Heart Healthy Cookbookemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The health of your heart has a lot to do with the foods you eat. To help busy people and families shop for, prepare, and serve healthy meals, the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health created and published Keep the Beat Recipes: Deliciously Healthy Dinners. The new cookbook features 75 simple and delicious recipes influenced by Asian, Latino, Mediterranean, and American cuisine that are good for your heart and taste great too.
Source: Cardiovascular / Cardiology News From Medical News Today - November 12, 2009 Category: Cardiology Tags: Nutrition / Diet Source Type: news

Gore Receives European CE Mark Approval For Next Generation Conformable GORE TAG(R) Thoracic Endoprosthesisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
W.L. Gore & Associates (Gore) announced that it has received European CE Mark approval for the next generation GORE TAG® Thoracic Endoprosthesis. The device is available in an expanded portfolio of sizes to meet a broad range of patient needs and was engineered to treat multiple etiologies including thoracic aortic aneurysms (TAAs), traumatic aortic transections and thoracic aortic dissections. Prof.
Source: Cardiovascular / Cardiology News From Medical News Today - November 12, 2009 Category: Cardiology Tags: Cardiovascular / Cardiology Source Type: news

Fasting on Alternate Days May Make Dieting Easieremail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Title: Fasting on Alternate Days May Make Dieting EasierCategory: Health NewsCreated: 11/11/2009 2:10:00 PMLast Editorial Review: 11/12/2009
Source: MedicineNet Cholesterol General - November 12, 2009 Category: Cardiology Source Type: consumer

Surgery Not Always Best for Narrowed Kidney Arteriesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Title: Surgery Not Always Best for Narrowed Kidney ArteriesCategory: Health NewsCreated: 11/11/2009 4:10:00 PMLast Editorial Review: 11/12/2009
Source: MedicineNet Heart General - November 12, 2009 Category: Cardiology Source Type: consumer

Cardiovascular risk factors in Assyrians/Syrians and native Swedes with type 2 diabetes: a population-based epidemiological studyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: Swedish-born subjects had higher prevalence of increased triglycerides and hypertension than Assyrians/Syrians. Total cholesterol and HbA1c did not differ between the two ethnic groups.
Source: Cardiovascular Diabetology - November 12, 2009 Category: Cardiology Authors: Marina TaloyanAlexandre WajngotSven-Erik JohanssonJonas ToviJan Sundquist Source Type: journals

Elevated plasma levels of TNF-alpha and Interleukin-6 in patients with diastolic dysfunction and glucose metabolism disordersemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: This study reveals that increased plasma levels of IL-6 and TNF-alpha were associated with LVDD. These findings suggest a link between low-grade inflammation and the presence of LVDD. An active proinflammatory process may be of importance in the pathogenesis of diastolic dysfunction.
Source: Cardiovascular Diabetology - November 12, 2009 Category: Cardiology Authors: Wilfried DinhReiner FuthWerner NicklThomas KrahnPeter EllinghausThomas ScheffoldLars BansemirAlexander BufeM. Coll BarrosoMark Lankisch Source Type: journals

CVN: MADIT-CRTemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Multicenter Automatic Defibrillator Implantation Trial-Cardiac Resynchronization Therapy (MADIT-CRT)
Source: Cardiosource - November 12, 2009 Category: Cardiology Source Type: organizations

The impact of renal insufficiency and anaemia on survival in patients with cardiovascular disease: a cohort studyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: In patients with cardiovascular disease in the community, chronic kidney disease and anaemia occur commonly. The presence of chronic kidney disease carries an increased mortality risk which increases in an additive way with the addition of anaemia. These results suggest that early primary care diagnosis and management of this high risk group may be worthwhile.
Source: BMC Cardiovascular Disorders - November 12, 2009 Category: Cardiology Authors: Jocelyn AndersonLiam GlynnJohn NewellAlberto IglesiasDonal ReddanAndrew Murphy Source Type: journals

AF News: Editor: Shih-Ann Chen, M.D.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Source: Journal of Cardiovascular Electrophysiology - November 12, 2009 Category: Cardiology Source Type: journals

Adenosine Triphosphate Exposes Dormant Superior Vena Cava Conduction Responsible for Recurrent Atrial Fibrillationemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Source: Journal of Cardiovascular Electrophysiology - November 12, 2009 Category: Cardiology Authors: SHINSUKE MIYAZAKI, ATSUSHI KOBORI, TAISHI KUWAHARA, ATSUSHI TAKAHASHI Source Type: journals

Triggering Pulmonary Veins: A Paradoxical Predictor for Atrial Fibrillation Recurrence After PV Isolationemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Triggering Pulmonary Veins and Recurrence After Ablation. Purpose: To identify procedural parameters predicting recurrence of atrial fibrillation (AF) after a first circumferential pulmonary vein isolation (CPVI). Methods: One hundred seventy-one patients undergoing CARTO-guided CPVI for recurrent AF with a left atrial (LA) diameter
Source: Journal of Cardiovascular Electrophysiology - November 12, 2009 Category: Cardiology Authors: YVES DE GREEF, RENE TAVERNIER, YVES VANDEKERCKHOVE, MATTIAS DUYTSCHAEVER Source Type: journals

Percutaneous Access of the Epicardial Space for Mapping Ventricular and Supraventricular Arrhythmias in Patients With and Without Prior Cardiac Surgeryemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: In patients without prior cardiac surgery, percutaneous epicardial access can be obtained in the majority of patients. Prior cardiac surgery precludes access in the most patients and when possible adhesions may limit catheter movement. Repeat access is possible in the majority of patients without the installation of intrapericardial glucocorticoid at the first procedure. (J Cardiovasc Electrophysiol, Vol. pp. 1[ndash]6)
Source: Journal of Cardiovascular Electrophysiology - November 12, 2009 Category: Cardiology Authors: KURT C. ROBERTS-THOMSON, JENS SEILER, DANIEL STEVEN, KEIICHI INADA, GREGORY F. MICHAUD, ROY M. JOHN, BRUCE A. KOPLAN, LAURENCE M. EPSTEIN, WILLIAM G. STEVENSON, USHA B. TEDROW Source Type: journals

High-Density Mapping of the Sinus Node in Humans: Role of Preferential Pathways and the Effect of Remodelingemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion: The functional sinus node complex demonstrates dynamic changes in activation. There are preferential pathways of conduction from sinus node to atrial myocardium. The remodeled atria demonstrate longer conduction times along preferential pathways and a restricted functional sinus node complex. (J Cardiovasc Electrophysiol, Vol. pp. 1[ndash]8)
Source: Journal of Cardiovascular Electrophysiology - November 12, 2009 Category: Cardiology Authors: MARTIN K. STILES, ANTHONY G. BROOKS, KURT C. ROBERTS-THOMSON, PAWEL KUKLIK, BOBBY JOHN, GLENN D. YOUNG, JONATHAN M. KALMAN, PRASHANTHAN SANDERS Source Type: journals

Outcomes of medical therapy in renal artery stenosis similar to revascularisation with lower riskemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Source: NEJM Area: News A controlled trial found that patients with renal artery stenosis who were assigned to revascularisation in addition to medical therapy had no statistically significant benefits and were at risk of significant complications.   Renal artery stenosis due to atherosclerosis is fairly common and has significant morbidity and mortality. Traditional treatment has concentrated on revascularisation, initially using open surgery and now more often using endovascular techniques. There is, however, limited evidence on the benefits of revascularisation, and this non-blinded trial was intended to inves...
Source: NeLM - Cardiovascular Medicine - November 12, 2009 Category: Cardiology Source Type: organizations

Review: Cardioversion of atrial fibrillation and the use of antiarrhythmic drugsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Source: Heart Area: News This review on the treatment of atrial fibrillation (AF) looks at the following:   . Indications for cardioversion of AF . Anti-arrhythmic drugs used for cardioversion or prevention of AF recurrence (digoxin, beta-blockers, non-dihydropyridine calcium antagonists, quinidine, disopyramide, propafenone, procainamide, dofetilide, amiodarone, sotalol, flecainide, dronedarone) . Non-anti-arrhythmic agents . Optimal management of patients with AF requiring rhythm control   The authors note that large RCTs have shown that a rhythm control strategy (using antiarrhythm...
Source: NeLM - Cardiovascular Medicine - November 12, 2009 Category: Cardiology Source Type: organizations

Review: Advances in antiplatelet treatment for acute coronary syndromesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This article reviews the evidence for clopidogrel, prasugrel and ticagrelor in acute coronary syndromes, and provides recommendations on their optimal use in clinical practice.   The authors note that a lack of head to head trials of prasugrel and ticagrelor limits the comparison of these agents; nevertheless the data so far suggest that both are 'potent agents with improved ischemic benefits in comparison to clopidogrel.  The improved benefit comes with the price of increased bleeding. As such, careful patient selection and balancing of benefit-risk is warranted to optimise their use in clinical practice.'
Source: NeLM - Cardiovascular Medicine - November 12, 2009 Category: Cardiology Source Type: organizations

Change in US heparin potencyemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Source: JAMA Area: News The FDA has warned US health professionals of a change to the official (USP) standards for heparin manufacture that will result in a fall in the potency of US heparin by up to 10%. This will mainly be relevant to patients receiving IV heparin as SC bioavailability is more variable anyway.   Health professionals elsewhere are NOT affected by this change unless they are using heparin to USP standards: the new USP potency now matches the World Health Organisation's International Standard unit dose that is used in Europe.   UK practitioners are only likely to be affected if they take over...
Source: NeLM - Cardiovascular Medicine - November 12, 2009 Category: Cardiology Source Type: organizations

Blood transfusion linked to STEMI mortality, causality remains uncertainemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Red blood cell transfusion is associated with increased mortality in patients with ST-segment elevation myocardial infarction, researchers report.
Source: MedWire News - Cardiology - November 12, 2009 Category: Cardiology Source Type: news

S100B Interaction With the Receptor for Advanced Glycation End Products (RAGE). A Novel Receptor-Mediated Mechanism for Myocyte Apoptosis Postinfarction.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: These results suggest that interaction of RAGE and its ligand S100B after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53 signaling. This receptor-mediated mechanism is uniquely amenable to therapeutic intervention. PMID: 19910580 [PubMed - as supplied by publisher]
Source: Circulation Research - November 12, 2009 Category: Cardiology Authors: Tsoporis JN, Izhar S, Leong-Poi H, Desjardins JF, Huttunen HJ, Parker TG Tags: Circ Res Source Type: journals

Monoamine Oxidase A-Mediated Enhanced Catabolism of Norepinephrine Contributes to Adverse Remodeling and Pump Failure in Hearts With Pressure Overload.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: In addition to adrenergic receptor-dependent mechanisms, enhanced MAO-A activity coupled with increased intramyocardial norepinephrine availability results in increased reactive oxygen species generation, contributing to maladaptive remodeling and left ventricular dysfunction in hearts subjected to chronic stress. PMID: 19910579 [PubMed - as supplied by publisher]
Source: Circulation Research - November 12, 2009 Category: Cardiology Authors: Kaludercic N, Takimoto E, Nagayama T, Feng N, Lai EW, Bedja D, Chen K, Gabrielson KL, Blakely RD, Shih JC, Pacak K, Kass DA, Di Lisa F, Paolocci N Tags: Circ Res Source Type: journals

CXCL4 Downregulates the Atheroprotective Hemoglobin Receptor CD163 in Human Macrophages.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: CXCL4 may promote atherogenesis by suppressing CD163 in macrophages, which are then unable to upregulate the atheroprotective enzyme heme oxygenase-1 in response to hemoglobin. PMID: 19910578 [PubMed - as supplied by publisher]
Source: Circulation Research - November 12, 2009 Category: Cardiology Authors: Gleissner CA, Shaked I, Erbel C, Böckler D, Katus HA, Ley K Tags: Circ Res Source Type: journals

Angiotensin II Type 1 Receptor-Mediated Upregulation of Calcineurin Activity Underlies Impairment of Cardioprotective Signaling in Diabetic Hearts.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: These results suggest that the diabetic heart is refractory to protection by Jak2-activating ligands because of AT1 receptor-mediated upregulation of calcineurin activity. PMID: 19910577 [PubMed - as supplied by publisher]
Source: Circulation Research - November 12, 2009 Category: Cardiology Authors: Hotta H, Miura T, Miki T, Togashi N, Maeda T, Kim SJ, Tanno M, Yano T, Kuno A, Itoh T, Satoh T, Terashima Y, Ishikawa S, Shimamoto K Tags: Circ Res Source Type: journals

The Cellular Prion Protein Identifies Bipotential Cardiomyogenic Progenitors.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: PrP(+) cells from beating embryoid bodies (EBs) frequently included nascent Myhc(+) cardiomyocytes. Cultured PrP(+) cells further differentiated, giving rise to cardiac troponin I(+) definitive cardiomyocytes with either an atrial or a ventricular identity. These cells were electrophysiologically functional and able to survive in vivo after transplantation. Combining PrP with a second marker, platelet-derived growth factor receptor (PDGFR)alpha, enabled us to identify an earlier cardiomyogenic population from prebeating EBs, the PrP(+)PDGFRalpha(+) (PRa) cells. The Myhc(-) PRa cells expressed cardiac transcrip...
Source: Circulation Research - November 12, 2009 Category: Cardiology Authors: Hidaka K, Shirai M, Lee JK, Wakayama T, Kodama I, Schneider MD, Morisaki T Tags: Circ Res Source Type: journals

Cardioprotection by CaMKII-{delta}B Is Mediated by Phosphorylation of Heat Shock Factor 1 and Subsequent Expression of Inducible Heat Shock Protein 70.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusions: We conclude that cardiac CaMKII-deltaB and CaMKII-deltaC were inversely regulated in response to oxidative stress and IR injury, and that in contrast to CaMKII-deltaC, CaMKII-deltaB serves as a potent suppressor of cardiomyocyte apoptosis triggered by multiple death-inducing stimuli via phosphorylation of HSF1 and subsequent induction of iHSP70, marking both CaMKII-delta isoforms as promising therapeutic targets for the treatment of ischemic heart disease. PMID: 19910575 [PubMed - as supplied by publisher]
Source: Circulation Research - November 12, 2009 Category: Cardiology Authors: Peng W, Zhang Y, Zheng M, Cheng H, Zhu W, Cao CM, Xiao RP Tags: Circ Res Source Type: journals

Leptin Enhances the Potency of Circulating Angiogenic Cells Via Src Kinase and Integrin {alpha}v{beta}5. Implications for Angiogenesis in Human Obesity.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSIONS: Our results point to the ObR-Src kinase-alphavbeta5 cross talk as a distinct novel component of the network of specific interactions between integrins and cytokine receptors in angiogenesis. PMID: 19910644 [PubMed - as supplied by publisher]
Source: Arteriosclerosis, Thrombosis and Vascular Biology - November 12, 2009 Category: Cardiology Authors: Heida NM, Leifheit-Nestler M, Schroeter MR, Müller JP, Cheng IF, Henkel S, Limbourg A, Limbourg FP, Alves F, Quigley JP, Ruggeri ZM, Hasenfuss G, Konstantinides S, Schäfer K Tags: Arterioscler Thromb Vasc Biol Source Type: journals

Altered Plasma Fibrin Clot Properties Are Associated With In-Stent Thrombosis.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSIONS: IST patients tend to form dense fibrin clots resistant to lysis, and altered plasma fibrin clot features might contribute to the occurrence of IST. PMID: 19910643 [PubMed - as supplied by publisher]
Source: Arteriosclerosis, Thrombosis and Vascular Biology - November 12, 2009 Category: Cardiology Authors: Undas A, Zalewski J, Krochin M, Siudak Z, Sadowski M, Pregowski J, Dudek D, Janion M, Witkowski A, Zmudka K Tags: Arterioscler Thromb Vasc Biol Source Type: journals

Loss of Stearoyl-CoA Desaturase-1 Attenuates Adipocyte Inflammation. Effects of Adipocyte-Derived Oleate.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSIONS: Loss of SCD1 attenuates adipocyte inflammation and its paracrine regulation of inflammation in macrophages and endothelial cells. The reduced oleate level is linked to the inflammation-modulating effects of SCD1 deficiency. PMID: 19910642 [PubMed - as supplied by publisher]
Source: Arteriosclerosis, Thrombosis and Vascular Biology - November 12, 2009 Category: Cardiology Authors: Liu X, Miyazaki M, Flowers MT, Sampath H, Zhao M, Chu K, Paton CM, Joo DS, Ntambi JM Tags: Arterioscler Thromb Vasc Biol Source Type: journals

Obesity Genotype Score and Cardiovascular Risk in Women With Type 2 Diabetes Mellitus.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSIONS: Obesity-predisposing variants may jointly affect CVD risk among women with diabetes. PMID: 19910641 [PubMed - as supplied by publisher]
Source: Arteriosclerosis, Thrombosis and Vascular Biology - November 12, 2009 Category: Cardiology Authors: He M, Cornelis MC, Franks PW, Zhang C, Hu FB, Qi L Tags: Arterioscler Thromb Vasc Biol Source Type: journals

NADPH Oxidases: Functions and Pathologies in the Vasculature.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Reactive oxygen species are ubiquitous signaling molecules in biological systems. Four members of the NADPH oxidase (Nox) enzyme family are important sources of reactive oxygen species in the vasculature: Nox1, Nox2, Nox4, and Nox5. Signaling cascades triggered by stresses, hormones, vasoactive agents, and cytokines control the expression and activity of these enzymes and of their regulatory subunits, among which p22phox, p47phox, Noxa1, and p67phox are present in blood vessels. Vascular Nox enzymes are also regulated by Rac, ClC-3, Poldip2, and protein disulfide isomerase. Multiple Nox subtypes, simultaneously present...
Source: Arteriosclerosis, Thrombosis and Vascular Biology - November 12, 2009 Category: Cardiology Authors: Lassègue B, Griendling KK Tags: Arterioscler Thromb Vasc Biol Source Type: journals

Genetic Association and Interaction Analysis of USF1 and APOA5 on Lipid Levels and Atherosclerosis.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSIONS: Our findings in these unique samples reinforce the roles of APOA5 and USF1 variants on cardiovascular phenotypes and suggest that both genes contribute to lipid levels and aortic atherosclerosis individually and possibly through epistatic effects. PMID: 19910639 [PubMed - as supplied by publisher]
Source: Arteriosclerosis, Thrombosis and Vascular Biology - November 12, 2009 Category: Cardiology Authors: Laurila PP, Naukkarinen J, Kristiansson K, Ripatti S, Kauttu T, Silander K, Salomaa V, Perola M, Karhunen PJ, Barter PJ, Ehnholm C, Peltonen L Tags: Arterioscler Thromb Vasc Biol Source Type: journals

Loss of Endothelial Tie1 Receptor Impairs Lymphatic Vessel Development.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSIONS: Our data show that loss of Tie1 results in lymphatic vascular abnormalities that precede the blood vessel phenotype. These findings indicate that Tie1 is involved in lymphangiogenesis and suggest differential requirements for Tie1 signaling in the 2 vascular compartments. PMID: 19910638 [PubMed - as supplied by publisher]
Source: Arteriosclerosis, Thrombosis and Vascular Biology - November 12, 2009 Category: Cardiology Authors: D'Amico G, Korhonen E, Waltari M, Saharinen P, Laakkonen P, Alitalo K Tags: Arterioscler Thromb Vasc Biol Source Type: journals

Claudin-5 as a Novel Estrogen Target in Vascular Endothelium.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSIONS: We describe claudin-5 as a novel estrogen target in vascular endothelium and show in vivo (brain endothelium) and in vitro (brain and heart endothelium) effects of estrogen on claudin-5 levels. The estrogen-induced increase in junctional protein levels may lead to an improvement in vascular structural integrity and barrier function of vascular endothelium. PMID: 19910637 [PubMed - as supplied by publisher]
Source: Arteriosclerosis, Thrombosis and Vascular Biology - November 12, 2009 Category: Cardiology Authors: Burek M, Arias-Loza PA, Roewer N, Förster CY Tags: Arterioscler Thromb Vasc Biol Source Type: journals

Metabolism of Very-Low-Density Lipoprotein and Low-Density Lipoprotein Containing Apolipoprotein C-III and Not Other Small Apolipoproteins.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSIONS: The results suggest that apoCIII strongly inhibits hepatic uptake of VLDL and IDL overriding the opposite influence of apoE when both are present. The presence of apoCIII on dense VLDL is not associated with slow conversion to IDL, a lipoprotein lipase-dependent process; but when on light LDL, apoCIII is associated with enhanced conversion to dense LDL, a process involving hepatic lipase. PMID: 19910636 [PubMed - as supplied by publisher]
Source: Arteriosclerosis, Thrombosis and Vascular Biology - November 12, 2009 Category: Cardiology Authors: Mendivil CO, Zheng C, Furtado J, Lel J, Sacks FM Tags: Arterioscler Thromb Vasc Biol Source Type: journals

CD11c Expression in Adipose Tissue and Blood and Its Role in Diet-Induced Obesity.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSIONS: Diet-induced obesity increased CD11c in both AT and blood in mice and humans. CD11c plays an important role in T-cell accumulation and activation in AT, and contributes to insulin resistance associated with obesity. PMID: 19910635 [PubMed - as supplied by publisher]
Source: Arteriosclerosis, Thrombosis and Vascular Biology - November 12, 2009 Category: Cardiology Authors: Wu H, Perrard XD, Wang Q, Perrard JL, Polsani VR, Jones PH, Smith CW, Ballantyne CM Tags: Arterioscler Thromb Vasc Biol Source Type: journals

Human Apolipoprotein A-II Determines Plasma Triglycerides by Regulating Lipoprotein Lipase Activity and High-Density Lipoprotein Proteome.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSIONS: ApoA-II plays a crucial role in triglyceride catabolism by regulating LPL activity, at least in part, through HDL proteome modulation. PMID: 19910634 [PubMed - as supplied by publisher]
Source: Arteriosclerosis, Thrombosis and Vascular Biology - November 12, 2009 Category: Cardiology Authors: Julve J, Escolà-Gil JC, Rotllan N, Fiévet C, Vallez E, de la Torre C, Ribas V, Sloan JH, Blanco-Vaca F Tags: Arterioscler Thromb Vasc Biol Source Type: journals

Hemorphin 7 Reflects Hemoglobin Proteolysis in Abdominal Aortic Aneurysm.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSIONS: Our results suggest that circulating H7 peptides may reflect proteolysis of hemoglobin in the aneurysmal intraluminal thrombus and may be used as a biological marker of pathological vascular remodeling. PMID: 19910633 [PubMed - as supplied by publisher]
Source: Arteriosclerosis, Thrombosis and Vascular Biology - November 12, 2009 Category: Cardiology Authors: Dejouvencel T, Féron D, Rossignol P, Sapoval M, Kauffmann C, Piot JM, Michel JB, Fruitier-Arnaudin I, Meilhac O Tags: Arterioscler Thromb Vasc Biol Source Type: journals

Thiazolidinediones Reduce Pathological Neovascularization in Ischemic Retina Via an Adiponectin-Dependent Mechanism.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSIONS: These data show that TZDs attenuate pathological retinal microvessel formation through APN-mediated modulation of TNF-alpha production. PMID: 19910632 [PubMed - as supplied by publisher]
Source: Arteriosclerosis, Thrombosis and Vascular Biology - November 12, 2009 Category: Cardiology Authors: Higuchi A, Ohashi K, Shibata R, Sono-Romanelli S, Walsh K, Ouchi N Tags: Arterioscler Thromb Vasc Biol Source Type: journals

Natural Killer T Cells Are Involved in Adipose Tissues Inflammation and Glucose Intolerance in Diet-Induced Obese Mice.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSIONS: NKT cells play a crucial role in the development of adipose tissue inflammation and glucose intolerance in diet-induced obesity. PMID: 19910631 [PubMed - as supplied by publisher]
Source: Arteriosclerosis, Thrombosis and Vascular Biology - November 12, 2009 Category: Cardiology Authors: Ohmura K, Ishimori N, Ohmura Y, Tokuhara S, Nozawa A, Horii S, Andoh Y, Fujii S, Iwabuchi K, Onoé K, Tsutsui H Tags: Arterioscler Thromb Vasc Biol Source Type: journals

Hemoglobin Levels Predict Diabetic Retinopathy (CME/CE)email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
An already routine blood test may identify juvenile-onset diabetic patients at heightened risk for proliferative retinopathy, researchers said.
Source: MedPage Today Cardiovascular - November 11, 2009 Category: Cardiology Source Type: news

Failure of Ancrod and Desmoteplase in Acute Ischemic Strokeemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In this video blog, Dr. Mark Alberts discusses the results of 2 studies showing the failure of Ancrod and desmoteplase therapy for acute ischemic stroke. Medscape Neurology & Neurosurgery
Source: Medscape Cardiology Headlines - November 11, 2009 Category: Cardiology Tags: Neurology & Neurosurgery Source Type: info

ASTRAL finds no benefit of revascularization over medical therapy alone for renal-artery stenosisemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Percutaneous revascularization of atherosclerotic renal arteries improves patency, but its benefits on renal function have been evaluated only in small studies. The 806-patient ASTRAL trial found no evidence of benefit from revascularization.
Source: theHeart.org - November 11, 2009 Category: Cardiology Source Type: info